Gene/Protein Characteristic Table for FXC10565

Species
human

Product ID
FXC10565

Corresponding
HaloTag Clone PID

ORF Sequence
DNA sequence (978 bp)
Protein sequence (326 aa)

Linker Type
Flexi type
The extra Val codon is attached to the 3'-end of the ORF, because a Pme I site ...

Cloning Site
SgfI-PmeI

GenBank Accession
ORF sequence is derived from [AB528631]

Gene
KIBB6475

Symbol
CDK6
Alias : PLSTIRE

Description
cyclin-dependent kinase 6

Original Clone ID
cs01075

Features of the cloned ORF sequence

Length: 978 bp
Restriction map A Restriction map B
Genomic Structure
Features of the protein sequence

Length: 326 aa
Result of homology search against nr database ( FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
NP_001250 1.7e-117 100.0 cyclin-dependen...
Homo sapiens
AAQ02556 1.7e-117 100.0 cyclin-dependen...
synthetic construct
XP_003252507 4.4e-117 99.4 cyclin-dependen...
Nomascus leucogenys
XP_003475150 8.3e-116 98.8 cyclin-dependen...
Cavia porcellus
XP_003782715 1.1e-115 99.4 cyclin-dependen...
Otolemur garnettii

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
[ zoom out (x2) ] PD000001 PF00069 SM00219 SM00220 PS50011 PS00107 PS00108

Result of InterProScan

Search method interpro_ID From To Entry Definition
BlastProDom IPR000719 19 291 PD000001 Protein kinase
HMMPfam IPR000719 13 300 PF00069 Protein kinase
HMMSmart IPR001245 13 300 SM00219 Tyrosine protein kinase
IPR002290 13 300 SM00220 Serine/threonine protein kinase
ProfileScan IPR000719 13 300 PS50011 Protein kinase
ScanRegExp IPR000719 19 43 PS00107 Protein kinase
IPR008271 141 153 PS00108 Serine/threonine protein kinase

Result of homology search against disease genes in OMIM database
(FASTA output, Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%)
NP_001250 326 603368,612223 100.0 100.0
NP_001138778 326 603368,612223 100.0 100.0
NP_000066 303 123829,609048 87.9 90.8
NP_001777 297 116940 76.3 90.2
NP_001124301 297 116940 76.3 90.2
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