Result of FASTA (omim) for pF1KB6475
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6475, 326 aa
  1>>>pF1KB6475 326 - 326 aa - 326 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 13.3598+/-0.000714; mu= -25.5571+/- 0.041
 mean_var=791.6466+/-184.224, 0's: 0 Z-trim(114.5): 1178  B-trim: 1813 in 2/55
 Lambda= 0.045584
 statistics sampled from 22716 (24456) to 22716 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.287), width:  16
 Scan time:  7.870

The best scores are:                                      opt bits E(85289)
NP_001250 (OMIM: 603368,616080) cyclin-dependent k ( 326) 2171 158.7 1.5e-38
NP_001138778 (OMIM: 603368,616080) cyclin-dependen ( 326) 2171 158.7 1.5e-38
XP_006715898 (OMIM: 603368,616080) PREDICTED: cycl ( 326) 2171 158.7 1.5e-38
NP_000066 (OMIM: 123829,609048) cyclin-dependent k ( 303) 1396 107.7 3.2e-23
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297)  879 73.7 5.4e-13
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297)  879 73.7 5.4e-13
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297)  879 73.7 5.4e-13
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305)  867 72.9 9.6e-13
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298)  851 71.8   2e-12
NP_277022 (OMIM: 176873) cyclin-dependent kinase 1 ( 526)  784 67.8 5.9e-11
NP_277025 (OMIM: 176873) cyclin-dependent kinase 1 ( 565)  784 67.8 6.1e-11
XP_011540798 (OMIM: 176873) PREDICTED: cyclin-depe ( 578)  784 67.8 6.2e-11
NP_277024 (OMIM: 176873) cyclin-dependent kinase 1 ( 748)  784 68.0 7.3e-11
XP_011540797 (OMIM: 176873) PREDICTED: cyclin-depe ( 760)  784 68.0 7.3e-11
XP_016858417 (OMIM: 176873) PREDICTED: cyclin-depe ( 761)  784 68.0 7.3e-11
XP_011540796 (OMIM: 176873) PREDICTED: cyclin-depe ( 770)  784 68.0 7.4e-11
XP_016858416 (OMIM: 176873) PREDICTED: cyclin-depe ( 770)  784 68.0 7.4e-11
NP_001278274 (OMIM: 176873) cyclin-dependent kinas ( 772)  784 68.0 7.4e-11
XP_016858415 (OMIM: 176873) PREDICTED: cyclin-depe ( 781)  784 68.0 7.5e-11
NP_277021 (OMIM: 176873) cyclin-dependent kinase 1 ( 782)  784 68.0 7.5e-11
XP_006711128 (OMIM: 176873) PREDICTED: cyclin-depe ( 785)  784 68.0 7.5e-11
XP_016858414 (OMIM: 176873) PREDICTED: cyclin-depe ( 791)  784 68.0 7.5e-11
XP_011540795 (OMIM: 176873) PREDICTED: cyclin-depe ( 794)  784 68.0 7.5e-11
NP_001778 (OMIM: 176873) cyclin-dependent kinase 1 ( 795)  784 68.0 7.5e-11
XP_011540794 (OMIM: 176873) PREDICTED: cyclin-depe ( 804)  784 68.0 7.6e-11
XP_011540793 (OMIM: 176873) PREDICTED: cyclin-depe ( 804)  784 68.0 7.6e-11
XP_011540792 (OMIM: 176873) PREDICTED: cyclin-depe ( 804)  784 68.0 7.6e-11
NP_277071 (OMIM: 116951) cyclin-dependent kinase 1 ( 770)  778 67.6 9.7e-11
NP_001300911 (OMIM: 116951) cyclin-dependent kinas ( 779)  778 67.6 9.8e-11
NP_076916 (OMIM: 116951) cyclin-dependent kinase 1 ( 780)  778 67.6 9.8e-11
NP_001300825 (OMIM: 116951) cyclin-dependent kinas ( 783)  778 67.6 9.8e-11
NP_443714 (OMIM: 603464) cyclin-dependent kinase 1 ( 360)  719 63.3   9e-10
XP_006721373 (OMIM: 603464) PREDICTED: cyclin-depe ( 343)  711 62.7 1.3e-09
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523)  684 61.2 5.6e-09
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523)  684 61.2 5.6e-09
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523)  684 61.2 5.6e-09
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523)  684 61.2 5.6e-09
XP_006721371 (OMIM: 603464) PREDICTED: cyclin-depe ( 354)  677 60.5   6e-09
XP_016879296 (OMIM: 603464) PREDICTED: cyclin-depe ( 337)  671 60.1 7.7e-09
NP_001790 (OMIM: 601955) cyclin-dependent kinase 7 ( 346)  668 59.9   9e-09
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292)  665 59.6 9.3e-09
XP_005257515 (OMIM: 615514) PREDICTED: cyclin-depe (1256)  673 60.9 1.6e-08
XP_016880242 (OMIM: 615514) PREDICTED: cyclin-depe (1261)  673 61.0 1.6e-08
XP_016880241 (OMIM: 615514) PREDICTED: cyclin-depe (1262)  673 61.0 1.6e-08
XP_016880239 (OMIM: 615514) PREDICTED: cyclin-depe (1262)  673 61.0 1.6e-08
XP_011523209 (OMIM: 615514) PREDICTED: cyclin-depe (1262)  673 61.0 1.6e-08
XP_016880240 (OMIM: 615514) PREDICTED: cyclin-depe (1262)  673 61.0 1.6e-08
XP_016880234 (OMIM: 615514) PREDICTED: cyclin-depe (1393)  673 61.0 1.7e-08
XP_011523200 (OMIM: 615514) PREDICTED: cyclin-depe (1393)  673 61.0 1.7e-08
XP_011523199 (OMIM: 615514) PREDICTED: cyclin-depe (1393)  673 61.0 1.7e-08


>>NP_001250 (OMIM: 603368,616080) cyclin-dependent kinas  (326 aa)
 initn: 2171 init1: 2171 opt: 2171  Z-score: 812.9  bits: 158.7 E(85289): 1.5e-38
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
              250       260       270       280       290       300

              310       320      
pF1KB6 QDLERCKENLDSHLPPSQNTSELNTA
       ::::::::::::::::::::::::::
NP_001 QDLERCKENLDSHLPPSQNTSELNTA
              310       320      

>>NP_001138778 (OMIM: 603368,616080) cyclin-dependent ki  (326 aa)
 initn: 2171 init1: 2171 opt: 2171  Z-score: 812.9  bits: 158.7 E(85289): 1.5e-38
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
              250       260       270       280       290       300

              310       320      
pF1KB6 QDLERCKENLDSHLPPSQNTSELNTA
       ::::::::::::::::::::::::::
NP_001 QDLERCKENLDSHLPPSQNTSELNTA
              310       320      

>>XP_006715898 (OMIM: 603368,616080) PREDICTED: cyclin-d  (326 aa)
 initn: 2171 init1: 2171 opt: 2171  Z-score: 812.9  bits: 158.7 E(85289): 1.5e-38
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
              250       260       270       280       290       300

              310       320      
pF1KB6 QDLERCKENLDSHLPPSQNTSELNTA
       ::::::::::::::::::::::::::
XP_006 QDLERCKENLDSHLPPSQNTSELNTA
              310       320      

>>NP_000066 (OMIM: 123829,609048) cyclin-dependent kinas  (303 aa)
 initn: 1370 init1: 1242 opt: 1396  Z-score: 537.9  bits: 107.7 E(85289): 3.2e-23
Smith-Waterman score: 1396; 70.2% identity (88.0% similar) in 299 aa overlap (9-304:2-299)

               10        20        30        40        50          
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEG---MPLS
               : ..:: ::::: :::: :.::::  ..:.::::: ::: .:  :   .:.:
NP_000        MATSRYEPVAEIGVGAYGTVYKARD-PHSGHFVALKSVRVPNGGGGGGGLPIS
                      10        20         30        40        50  

        60        70        80        90       100       110       
pF1KB6 TIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGV
       :.::::.::.::.:::::::::.:::..:::::: :.::::::::::: :::::.: ::.
NP_000 TVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGL
             60        70        80        90       100       110  

       120       130       140       150       160       170       
pF1KB6 PTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALT
       :.:::::.: :.::::::::.. .:::::::.::::::.: .::::::::::::.:::::
NP_000 PAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALT
            120       130       140       150       160       170  

       180       190       200       210       220       230       
pF1KB6 SVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGL
        ::::::::::::::::.::::::.::::::::::::::::: :.:..::::::.:.:::
NP_000 PVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGL
            180       190       200       210       220       230  

       240       250       260       270       280       290       
pF1KB6 PGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSH
       : :.::::::.::: ::  .. .:... : ...: : .:::. ::::: :::::. ::.:
NP_000 PPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQH
            240       250       260       270       280       290  

       300       310       320      
pF1KB6 PYFQDLERCKENLDSHLPPSQNTSELNTA
        :..  :                      
NP_000 SYLHKDEGNPE                  
            300                     

>>XP_005270360 (OMIM: 116940) PREDICTED: cyclin-dependen  (297 aa)
 initn: 682 init1: 217 opt: 879  Z-score: 354.2  bits: 73.7 E(85289): 5.4e-13
Smith-Waterman score: 879; 46.3% identity (76.3% similar) in 300 aa overlap (11-304:2-291)

               10        20        30        40        50        60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
                 ..:  . .::::.:: :.:.:  :. :. ::.:..:... :::.: ..::
XP_005          MEDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIR
                        10        20         30        40        50

               70        80        90       100       110          
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VP
       :...:..:.   :::.: : ::       ....: :.:: ...::  :::..: ::  . 
XP_005 EISLLKELR---HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMD
                  60        70             80        90        100 

      120       130       140       150       160       170        
pF1KB6 TETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-T
       .  .:....:.:.:. : ::.::.::::::::.:. ..: :::::::::: ... . . :
XP_005 SSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT
             110       120       130       140       150       160 

       180       190        200       210       220       230      
pF1KB6 SVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG
         :::::::.::::: :. :.::::.::.: ::::.  .::::.:.:..::: .:. ..:
XP_005 HEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG
             170       180       190       200       210       220 

        240       250         260       270       280       290    
pF1KB6 LPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSA
        :..: ::.  .:   ...: . .   . . : ..:: : ::: : : ..::::::.  :
XP_005 TPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMA
             230       240       250       260       270       280 

          300       310       320      
pF1KB6 LSHPYFQDLERCKENLDSHLPPSQNTSELNTA
       :.::::.::.                      
XP_005 LNHPYFNDLDNQIKKM                
             290                       

>>NP_001307847 (OMIM: 116940) cyclin-dependent kinase 1   (297 aa)
 initn: 682 init1: 217 opt: 879  Z-score: 354.2  bits: 73.7 E(85289): 5.4e-13
Smith-Waterman score: 879; 46.3% identity (76.3% similar) in 300 aa overlap (11-304:2-291)

               10        20        30        40        50        60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
                 ..:  . .::::.:: :.:.:  :. :. ::.:..:... :::.: ..::
NP_001          MEDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIR
                        10        20         30        40        50

               70        80        90       100       110          
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VP
       :...:..:.   :::.: : ::       ....: :.:: ...::  :::..: ::  . 
NP_001 EISLLKELR---HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMD
                  60        70             80        90        100 

      120       130       140       150       160       170        
pF1KB6 TETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-T
       .  .:....:.:.:. : ::.::.::::::::.:. ..: :::::::::: ... . . :
NP_001 SSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT
             110       120       130       140       150       160 

       180       190        200       210       220       230      
pF1KB6 SVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG
         :::::::.::::: :. :.::::.::.: ::::.  .::::.:.:..::: .:. ..:
NP_001 HEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG
             170       180       190       200       210       220 

        240       250         260       270       280       290    
pF1KB6 LPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSA
        :..: ::.  .:   ...: . .   . . : ..:: : ::: : : ..::::::.  :
NP_001 TPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMA
             230       240       250       260       270       280 

          300       310       320      
pF1KB6 LSHPYFQDLERCKENLDSHLPPSQNTSELNTA
       :.::::.::.                      
NP_001 LNHPYFNDLDNQIKKM                
             290                       

>>NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 iso  (297 aa)
 initn: 682 init1: 217 opt: 879  Z-score: 354.2  bits: 73.7 E(85289): 5.4e-13
Smith-Waterman score: 879; 46.3% identity (76.3% similar) in 300 aa overlap (11-304:2-291)

               10        20        30        40        50        60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
                 ..:  . .::::.:: :.:.:  :. :. ::.:..:... :::.: ..::
NP_001          MEDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIR
                        10        20         30        40        50

               70        80        90       100       110          
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VP
       :...:..:.   :::.: : ::       ....: :.:: ...::  :::..: ::  . 
NP_001 EISLLKELR---HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMD
                  60        70             80        90        100 

      120       130       140       150       160       170        
pF1KB6 TETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-T
       .  .:....:.:.:. : ::.::.::::::::.:. ..: :::::::::: ... . . :
NP_001 SSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT
             110       120       130       140       150       160 

       180       190        200       210       220       230      
pF1KB6 SVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG
         :::::::.::::: :. :.::::.::.: ::::.  .::::.:.:..::: .:. ..:
NP_001 HEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG
             170       180       190       200       210       220 

        240       250         260       270       280       290    
pF1KB6 LPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSA
        :..: ::.  .:   ...: . .   . . : ..:: : ::: : : ..::::::.  :
NP_001 TPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMA
             230       240       250       260       270       280 

          300       310       320      
pF1KB6 LSHPYFQDLERCKENLDSHLPPSQNTSELNTA
       :.::::.::.                      
NP_001 LNHPYFNDLDNQIKKM                
             290                       

>>NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 [Ho  (305 aa)
 initn: 761 init1: 318 opt: 867  Z-score: 349.8  bits: 72.9 E(85289): 9.6e-13
Smith-Waterman score: 928; 48.0% identity (77.0% similar) in 296 aa overlap (13-304:4-290)

               10        20        30        40        50        60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
                   .. : .::::.:: :.::.. .. :..::::..:..   ::.: ..::
NP_001          MDMFQKVEKIGEGTYGVVYKAKN-RETGQLVALKKIRLDLEMEGVPSTAIR
                        10        20         30        40        50

               70        80        90       100       110       120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
       :...:..:.   :::.:::.::     .  : :: :::: ..:::  :.:..:   .: .
NP_001 EISLLKELK---HPNIVRLLDV-----VHNERKLYLVFEFLSQDLKKYMDSTPGSELPLH
                  60             70        80        90       100  

              130       140       150       160       170          
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSV
        ::...::::.:..: :::::.::::::::.:..  : :::::::::: ..  . . :  
NP_001 LIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHE
            110       120       130       140       150       160  

     180       190        200       210       220       230        
pF1KB6 VVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLP
       ::::::::::.:: :. :.: ::.::.:::::::  :: :: :.:..::: .:. ..: :
NP_001 VVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTP
            170       180       190       200       210       220  

      240       250         260       270       280       290      
pF1KB6 GEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALS
       .:. ::  . ::  . .: . . . .:..: ...  :.:::.. : ..:..::.: .::.
NP_001 SEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALA
            230       240       250       260       270       280  

        300       310       320      
pF1KB6 HPYFQDLERCKENLDSHLPPSQNTSELNTA
       ::::.. :                      
NP_001 HPYFSSPEPSPAARQYVLQRFRH       
            290       300            

>>NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 iso  (298 aa)
 initn: 780 init1: 321 opt: 851  Z-score: 344.2  bits: 71.8 E(85289): 2e-12
Smith-Waterman score: 918; 48.5% identity (73.6% similar) in 299 aa overlap (11-305:2-291)

               10        20        30        40        50        60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
                 .... : .::::.:: :.:::. :  :. ::::..:..:  ::.: ..::
NP_001          MENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIR
                        10        20         30        40        50

               70        80        90       100       110       120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
       :...:..:.   :::.:.:.::        :.:: :::: . :::  ..:     :.:  
NP_001 EISLLKELN---HPNIVKLLDV-----IHTENKLYLVFEFLHQDLKKFMDASALTGIPLP
                  60             70        80        90       100  

              130       140       150       160       170          
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSV
        ::...::::.:: : :::::.::::::::.:... : :::::::::: ..  . . :  
NP_001 LIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE
            110       120       130       140       150       160  

     180       190        200       210       220       230        
pF1KB6 VVTLWYRAPEVLLQSSY-ATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLP
       ::::::::::.::  .: .: ::.::.:::::::  :. :: :.:..::: .:. ..: :
NP_001 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTP
            170       180       190       200       210       220  

      240       250         260       270       280       290      
pF1KB6 GEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALS
        :  ::  ...:  . .: . . : . : :  .:: :..:: . : ..: ::::: .::.
NP_001 DEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALA
            230       240       250       260       270       280  

        300       310       320      
pF1KB6 HPYFQDLERCKENLDSHLPPSQNTSELNTA
       ::.:::. .                     
NP_001 HPFFQDVTKPVPHLRL              
            290                      

>>NP_277022 (OMIM: 176873) cyclin-dependent kinase 11B i  (526 aa)
 initn: 496 init1: 220 opt: 784  Z-score: 317.7  bits: 67.8 E(85289): 5.9e-11
Smith-Waterman score: 784; 40.7% identity (74.5% similar) in 302 aa overlap (7-302:163-456)

                                       10        20        30      
pF1KB6                         MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNG
                                     ::. ....:. .: ::.:: :..:.: :. 
NP_277 TEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKD-KKT
            140       150       160       170       180        190 

         40        50        60        70        80        90      
pF1KB6 GRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTL
        ..:::::....  .::.:....::. ..  :.. .:::.: . .. . :  :   :. .
NP_277 DEIVALKRLKMEKEKEGFPITSLREINTI--LKA-QHPNIVTVREIVVGSNMD---KIYI
             200       210       220          230       240        

        100       110       120       130       140       150      
pF1KB6 VFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSS
       :...:..:: . .. . .: .: : .: .:.:::::.  ::.. ..::::: .:.:.. .
NP_277 VMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA
         250       260        270       280       290       300    

        160       170        180       190        200       210    
pF1KB6 GQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFR
       : .:..:::::: :.  . : : :::::::::::.:: .. :.: ::.:::::::.:.. 
NP_277 GILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT
          310       320       330       340       350       360    

          220       230       240       250       260           270
pF1KB6 RKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPI----EKFVTDID
       .:::: :.:..::..:..  .: :.:. ::    ::     . : .:     ..: . ..
NP_277 QKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLS
          370       380       390       400       410       420    

              280       290       300       310       320          
pF1KB6 ELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA    
       . : ::. : ::. :..:::: ..:.: ::..                            
NP_277 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSP
          430       440       450       460       470       480    

NP_277 RPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
          490       500       510       520      




326 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 17:19:49 2016 done: Fri Nov  4 17:19:51 2016
 Total Scan time:  7.870 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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