Result of FASTA (omim) for
pF1KB6475
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6475, 326 aa
1>>>pF1KB6475 326 - 326 aa - 326 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.3598+/-0.000714; mu= -25.5571+/- 0.041
mean_var=791.6466+/-184.224, 0's: 0 Z-trim(114.5): 1178 B-trim: 1813 in 2/55
Lambda= 0.045584
statistics sampled from 22716 (24456) to 22716 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.287), width: 16
Scan time: 7.870
The best scores are: opt bits E(85289)
NP_001250 (OMIM: 603368,616080) cyclin-dependent k ( 326) 2171 158.7 1.5e-38
NP_001138778 (OMIM: 603368,616080) cyclin-dependen ( 326) 2171 158.7 1.5e-38
XP_006715898 (OMIM: 603368,616080) PREDICTED: cycl ( 326) 2171 158.7 1.5e-38
NP_000066 (OMIM: 123829,609048) cyclin-dependent k ( 303) 1396 107.7 3.2e-23
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 879 73.7 5.4e-13
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 879 73.7 5.4e-13
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 879 73.7 5.4e-13
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 867 72.9 9.6e-13
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 851 71.8 2e-12
NP_277022 (OMIM: 176873) cyclin-dependent kinase 1 ( 526) 784 67.8 5.9e-11
NP_277025 (OMIM: 176873) cyclin-dependent kinase 1 ( 565) 784 67.8 6.1e-11
XP_011540798 (OMIM: 176873) PREDICTED: cyclin-depe ( 578) 784 67.8 6.2e-11
NP_277024 (OMIM: 176873) cyclin-dependent kinase 1 ( 748) 784 68.0 7.3e-11
XP_011540797 (OMIM: 176873) PREDICTED: cyclin-depe ( 760) 784 68.0 7.3e-11
XP_016858417 (OMIM: 176873) PREDICTED: cyclin-depe ( 761) 784 68.0 7.3e-11
XP_011540796 (OMIM: 176873) PREDICTED: cyclin-depe ( 770) 784 68.0 7.4e-11
XP_016858416 (OMIM: 176873) PREDICTED: cyclin-depe ( 770) 784 68.0 7.4e-11
NP_001278274 (OMIM: 176873) cyclin-dependent kinas ( 772) 784 68.0 7.4e-11
XP_016858415 (OMIM: 176873) PREDICTED: cyclin-depe ( 781) 784 68.0 7.5e-11
NP_277021 (OMIM: 176873) cyclin-dependent kinase 1 ( 782) 784 68.0 7.5e-11
XP_006711128 (OMIM: 176873) PREDICTED: cyclin-depe ( 785) 784 68.0 7.5e-11
XP_016858414 (OMIM: 176873) PREDICTED: cyclin-depe ( 791) 784 68.0 7.5e-11
XP_011540795 (OMIM: 176873) PREDICTED: cyclin-depe ( 794) 784 68.0 7.5e-11
NP_001778 (OMIM: 176873) cyclin-dependent kinase 1 ( 795) 784 68.0 7.5e-11
XP_011540794 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 784 68.0 7.6e-11
XP_011540793 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 784 68.0 7.6e-11
XP_011540792 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 784 68.0 7.6e-11
NP_277071 (OMIM: 116951) cyclin-dependent kinase 1 ( 770) 778 67.6 9.7e-11
NP_001300911 (OMIM: 116951) cyclin-dependent kinas ( 779) 778 67.6 9.8e-11
NP_076916 (OMIM: 116951) cyclin-dependent kinase 1 ( 780) 778 67.6 9.8e-11
NP_001300825 (OMIM: 116951) cyclin-dependent kinas ( 783) 778 67.6 9.8e-11
NP_443714 (OMIM: 603464) cyclin-dependent kinase 1 ( 360) 719 63.3 9e-10
XP_006721373 (OMIM: 603464) PREDICTED: cyclin-depe ( 343) 711 62.7 1.3e-09
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 684 61.2 5.6e-09
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 684 61.2 5.6e-09
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 684 61.2 5.6e-09
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 684 61.2 5.6e-09
XP_006721371 (OMIM: 603464) PREDICTED: cyclin-depe ( 354) 677 60.5 6e-09
XP_016879296 (OMIM: 603464) PREDICTED: cyclin-depe ( 337) 671 60.1 7.7e-09
NP_001790 (OMIM: 601955) cyclin-dependent kinase 7 ( 346) 668 59.9 9e-09
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 665 59.6 9.3e-09
XP_005257515 (OMIM: 615514) PREDICTED: cyclin-depe (1256) 673 60.9 1.6e-08
XP_016880242 (OMIM: 615514) PREDICTED: cyclin-depe (1261) 673 61.0 1.6e-08
XP_016880241 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 673 61.0 1.6e-08
XP_016880239 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 673 61.0 1.6e-08
XP_011523209 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 673 61.0 1.6e-08
XP_016880240 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 673 61.0 1.6e-08
XP_016880234 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 673 61.0 1.7e-08
XP_011523200 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 673 61.0 1.7e-08
XP_011523199 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 673 61.0 1.7e-08
>>NP_001250 (OMIM: 603368,616080) cyclin-dependent kinas (326 aa)
initn: 2171 init1: 2171 opt: 2171 Z-score: 812.9 bits: 158.7 E(85289): 1.5e-38
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)
10 20 30 40 50 60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
250 260 270 280 290 300
310 320
pF1KB6 QDLERCKENLDSHLPPSQNTSELNTA
::::::::::::::::::::::::::
NP_001 QDLERCKENLDSHLPPSQNTSELNTA
310 320
>>NP_001138778 (OMIM: 603368,616080) cyclin-dependent ki (326 aa)
initn: 2171 init1: 2171 opt: 2171 Z-score: 812.9 bits: 158.7 E(85289): 1.5e-38
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)
10 20 30 40 50 60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
250 260 270 280 290 300
310 320
pF1KB6 QDLERCKENLDSHLPPSQNTSELNTA
::::::::::::::::::::::::::
NP_001 QDLERCKENLDSHLPPSQNTSELNTA
310 320
>>XP_006715898 (OMIM: 603368,616080) PREDICTED: cyclin-d (326 aa)
initn: 2171 init1: 2171 opt: 2171 Z-score: 812.9 bits: 158.7 E(85289): 1.5e-38
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)
10 20 30 40 50 60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
250 260 270 280 290 300
310 320
pF1KB6 QDLERCKENLDSHLPPSQNTSELNTA
::::::::::::::::::::::::::
XP_006 QDLERCKENLDSHLPPSQNTSELNTA
310 320
>>NP_000066 (OMIM: 123829,609048) cyclin-dependent kinas (303 aa)
initn: 1370 init1: 1242 opt: 1396 Z-score: 537.9 bits: 107.7 E(85289): 3.2e-23
Smith-Waterman score: 1396; 70.2% identity (88.0% similar) in 299 aa overlap (9-304:2-299)
10 20 30 40 50
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEG---MPLS
: ..:: ::::: :::: :.:::: ..:.::::: ::: .: : .:.:
NP_000 MATSRYEPVAEIGVGAYGTVYKARD-PHSGHFVALKSVRVPNGGGGGGGLPIS
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 TIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGV
:.::::.::.::.:::::::::.:::..:::::: :.::::::::::: :::::.: ::.
NP_000 TVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 PTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALT
:.:::::.: :.::::::::.. .:::::::.::::::.: .::::::::::::.:::::
NP_000 PAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 SVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGL
::::::::::::::::.::::::.::::::::::::::::: :.:..::::::.:.:::
NP_000 PVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 PGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSH
: :.::::::.::: :: .. .:... : ...: : .:::. ::::: :::::. ::.:
NP_000 PPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQH
240 250 260 270 280 290
300 310 320
pF1KB6 PYFQDLERCKENLDSHLPPSQNTSELNTA
:.. :
NP_000 SYLHKDEGNPE
300
>>XP_005270360 (OMIM: 116940) PREDICTED: cyclin-dependen (297 aa)
initn: 682 init1: 217 opt: 879 Z-score: 354.2 bits: 73.7 E(85289): 5.4e-13
Smith-Waterman score: 879; 46.3% identity (76.3% similar) in 300 aa overlap (11-304:2-291)
10 20 30 40 50 60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
..: . .::::.:: :.:.: :. :. ::.:..:... :::.: ..::
XP_005 MEDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIR
10 20 30 40 50
70 80 90 100 110
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VP
:...:..:. :::.: : :: ....: :.:: ...:: :::..: :: .
XP_005 EISLLKELR---HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMD
60 70 80 90 100
120 130 140 150 160 170
pF1KB6 TETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-T
. .:....:.:.:. : ::.::.::::::::.:. ..: :::::::::: ... . . :
XP_005 SSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 SVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG
:::::::.::::: :. :.::::.::.: ::::. .::::.:.:..::: .:. ..:
XP_005 HEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 LPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSA
:..: ::. .: ...: . . . . : ..:: : ::: : : ..::::::. :
XP_005 TPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMA
230 240 250 260 270 280
300 310 320
pF1KB6 LSHPYFQDLERCKENLDSHLPPSQNTSELNTA
:.::::.::.
XP_005 LNHPYFNDLDNQIKKM
290
>>NP_001307847 (OMIM: 116940) cyclin-dependent kinase 1 (297 aa)
initn: 682 init1: 217 opt: 879 Z-score: 354.2 bits: 73.7 E(85289): 5.4e-13
Smith-Waterman score: 879; 46.3% identity (76.3% similar) in 300 aa overlap (11-304:2-291)
10 20 30 40 50 60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
..: . .::::.:: :.:.: :. :. ::.:..:... :::.: ..::
NP_001 MEDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIR
10 20 30 40 50
70 80 90 100 110
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VP
:...:..:. :::.: : :: ....: :.:: ...:: :::..: :: .
NP_001 EISLLKELR---HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMD
60 70 80 90 100
120 130 140 150 160 170
pF1KB6 TETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-T
. .:....:.:.:. : ::.::.::::::::.:. ..: :::::::::: ... . . :
NP_001 SSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 SVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG
:::::::.::::: :. :.::::.::.: ::::. .::::.:.:..::: .:. ..:
NP_001 HEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 LPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSA
:..: ::. .: ...: . . . . : ..:: : ::: : : ..::::::. :
NP_001 TPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMA
230 240 250 260 270 280
300 310 320
pF1KB6 LSHPYFQDLERCKENLDSHLPPSQNTSELNTA
:.::::.::.
NP_001 LNHPYFNDLDNQIKKM
290
>>NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 iso (297 aa)
initn: 682 init1: 217 opt: 879 Z-score: 354.2 bits: 73.7 E(85289): 5.4e-13
Smith-Waterman score: 879; 46.3% identity (76.3% similar) in 300 aa overlap (11-304:2-291)
10 20 30 40 50 60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
..: . .::::.:: :.:.: :. :. ::.:..:... :::.: ..::
NP_001 MEDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIR
10 20 30 40 50
70 80 90 100 110
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VP
:...:..:. :::.: : :: ....: :.:: ...:: :::..: :: .
NP_001 EISLLKELR---HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMD
60 70 80 90 100
120 130 140 150 160 170
pF1KB6 TETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-T
. .:....:.:.:. : ::.::.::::::::.:. ..: :::::::::: ... . . :
NP_001 SSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 SVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG
:::::::.::::: :. :.::::.::.: ::::. .::::.:.:..::: .:. ..:
NP_001 HEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 LPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSA
:..: ::. .: ...: . . . . : ..:: : ::: : : ..::::::. :
NP_001 TPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMA
230 240 250 260 270 280
300 310 320
pF1KB6 LSHPYFQDLERCKENLDSHLPPSQNTSELNTA
:.::::.::.
NP_001 LNHPYFNDLDNQIKKM
290
>>NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 [Ho (305 aa)
initn: 761 init1: 318 opt: 867 Z-score: 349.8 bits: 72.9 E(85289): 9.6e-13
Smith-Waterman score: 928; 48.0% identity (77.0% similar) in 296 aa overlap (13-304:4-290)
10 20 30 40 50 60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
.. : .::::.:: :.::.. .. :..::::..:.. ::.: ..::
NP_001 MDMFQKVEKIGEGTYGVVYKAKN-RETGQLVALKKIRLDLEMEGVPSTAIR
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
:...:..:. :::.:::.:: . : :: :::: ..::: :.:..: .: .
NP_001 EISLLKELK---HPNIVRLLDV-----VHNERKLYLVFEFLSQDLKKYMDSTPGSELPLH
60 70 80 90 100
130 140 150 160 170
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSV
::...::::.:..: :::::.::::::::.:.. : :::::::::: .. . . :
NP_001 LIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 VVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLP
::::::::::.:: :. :.: ::.::.::::::: :: :: :.:..::: .:. ..: :
NP_001 VVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 GEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALS
.:. :: . :: . .: . . . .:..: ... :.:::.. : ..:..::.: .::.
NP_001 SEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALA
230 240 250 260 270 280
300 310 320
pF1KB6 HPYFQDLERCKENLDSHLPPSQNTSELNTA
::::.. :
NP_001 HPYFSSPEPSPAARQYVLQRFRH
290 300
>>NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 iso (298 aa)
initn: 780 init1: 321 opt: 851 Z-score: 344.2 bits: 71.8 E(85289): 2e-12
Smith-Waterman score: 918; 48.5% identity (73.6% similar) in 299 aa overlap (11-305:2-291)
10 20 30 40 50 60
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
.... : .::::.:: :.:::. : :. ::::..:..: ::.: ..::
NP_001 MENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIR
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
:...:..:. :::.:.:.:: :.:: :::: . ::: ..: :.:
NP_001 EISLLKELN---HPNIVKLLDV-----IHTENKLYLVFEFLHQDLKKFMDASALTGIPLP
60 70 80 90 100
130 140 150 160 170
pF1KB6 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSV
::...::::.:: : :::::.::::::::.:... : :::::::::: .. . . :
NP_001 LIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 VVTLWYRAPEVLLQSSY-ATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLP
::::::::::.:: .: .: ::.::.::::::: :. :: :.:..::: .:. ..: :
NP_001 VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 GEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALS
: :: ...: . .: . . : . : : .:: :..:: . : ..: ::::: .::.
NP_001 DEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALA
230 240 250 260 270 280
300 310 320
pF1KB6 HPYFQDLERCKENLDSHLPPSQNTSELNTA
::.:::. .
NP_001 HPFFQDVTKPVPHLRL
290
>>NP_277022 (OMIM: 176873) cyclin-dependent kinase 11B i (526 aa)
initn: 496 init1: 220 opt: 784 Z-score: 317.7 bits: 67.8 E(85289): 5.9e-11
Smith-Waterman score: 784; 40.7% identity (74.5% similar) in 302 aa overlap (7-302:163-456)
10 20 30
pF1KB6 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNG
::. ....:. .: ::.:: :..:.: :.
NP_277 TEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKD-KKT
140 150 160 170 180 190
40 50 60 70 80 90
pF1KB6 GRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTL
..:::::.... .::.:....::. .. :.. .:::.: . .. . : : :. .
NP_277 DEIVALKRLKMEKEKEGFPITSLREINTI--LKA-QHPNIVTVREIVVGSNMD---KIYI
200 210 220 230 240
100 110 120 130 140 150
pF1KB6 VFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSS
:...:..:: . .. . .: .: : .: .:.:::::. ::.. ..::::: .:.:.. .
NP_277 VMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHA
250 260 270 280 290 300
160 170 180 190 200 210
pF1KB6 GQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFR
: .:..:::::: :. . : : :::::::::::.:: .. :.: ::.:::::::.:..
NP_277 GILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT
310 320 330 340 350 360
220 230 240 250 260 270
pF1KB6 RKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPI----EKFVTDID
.:::: :.:..::..:.. .: :.:. :: :: . : .: ..: . ..
NP_277 QKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLS
370 380 390 400 410 420
280 290 300 310 320
pF1KB6 ELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA
. : ::. : ::. :..:::: ..:.: ::..
NP_277 DQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSP
430 440 450 460 470 480
NP_277 RPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
490 500 510 520
326 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:19:49 2016 done: Fri Nov 4 17:19:51 2016
Total Scan time: 7.870 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]