HUGE

Gene/Protein Characteristic Table for KIAA1605

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00875
Accession No. :	AB046825
Description :	Non-lysosomal glucosylceramidase.
HUGO Gene Name :	glucosidase, beta (bile acid) 2 (GBA2)
Clone Name :	fj10791 [Vector Info]
Flexi ORF Clone :	pF1KSDA1605
Source :	Human fetal brain

Features of the cloned DNA sequence	Description

Length: 3757 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 609 bp

Genome contig ID gi89161216r_35626864
PolyA signal sequence
(AATAAA,-20)
+----*----+----*----+----*----+----
AGACACATGGGTACAAATAAAAGACCCAGAAAGCC
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
ATTAAGTGTGGTGTGTTTGAGCCCTCAGTCGTCCTGACAGGGCACAGGAG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 9 r 35726864 35739215 17 100.0 Perfect prediction

Features of the protein sequence	Description

Length: 922 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
CAI10983	100.0	glucosidase, be...	Homo sapiens
XP_001167830	99.5	bile acid beta-...	Pan troglodytes
Q9HCG7	99.5	Non-lysosomal g...	Homo sapiens
XP_001167862	97.2	bile acid beta-...	Pan troglodytes
XP_520565	99.0	bile acid beta-...	Pan troglodytes

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output)
No significant homologues
Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR006775 566 915 PF04685 Protein of unknown function DUF608

ScanRegExp IPR002202 199 206 PS00318 Hydroxymethylglutaryl-coenzyme A reductase

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR006775	566	915	PF04685	Protein of unknown function DUF608
ScanRegExp	IPR002202	199	206	PS00318	Hydroxymethylglutaryl-coenzyme A reductase

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 831 FELNVQAFAGGAMGAVNGMQPH 852 SECONDARY 22

2 871 YGLAATMIQELLPSGFCLWVIVI 893 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	831	FELNVQAFAGGAMGAVNGMQPH	852	SECONDARY	22
2	871	YGLAATMIQELLPSGFCLWVIVI	893	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: TTACAACTATGACAGCAGCTC

Primer_r
: GATAGTTTGGAGAGCACGGAC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 9

Experimental conditions

Panel name	: unigene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	609 bp
Genome contig ID	gi89161216r_35626864
PolyA signal sequence (AATAAA,-20)	+--------+--------+----*----+---- AGACACATGGGTACAAATAAAAGACCCAGAAAGCC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* ATTAAGTGTGGTGTGTTTGAGCCCTCAGTCGTCCTGACAGGGCACAGGAG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	9	r	35726864	35739215	17	100.0	Perfect prediction

Primer_f	: TTACAACTATGACAGCAGCTC
Primer_r	: GATAGTTTGGAGAGCACGGAC
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA1605

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information