HUGE

Gene/Protein Characteristic Table for KIAA1356

Link to : GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK06738
Accession No. :	AB037777
Description :	Sodium channel protein type 3 subunit alpha.
HUGO Gene Name :
Clone Name :	fj01605 [Vector Info]
Source :	Human fetal brain

Features of the cloned DNA sequence	Description

Length: 4183 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 2623 bp

Genome contig ID gi89161199r_165552284
PolyA signal sequence
(AATAAA,-21)
+----*----+----*----+----*----+----
CATAATTCTCCCATAATAAATTATATAAGGTGGCT
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AATTGGAATTCATTGGCTTCTTTCTGCTCAAGTCAATTTACACATCTACA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 2 r 165652284 165659222 3 99.1 Perfect prediction

Features of the protein sequence	Description

Length: 519 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
EAX11332	2.6e-203	100.0	sodium channel,...	Homo sapiens
XP_001152236	3.4e-203	100.0	similar to rat ...	Pan troglodytes
XP_001152176	3.4e-203	100.0	sodium channel,...	Pan troglodytes
EAX11335	3.5e-203	100.0	sodium channel,...	Homo sapiens
XP_001152817	3.6e-203	100.0	sodium channel,...	Pan troglodytes

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB032946	1.5e-24	31.9	KIAA1120
AB032949	2.7e-24	30.6	KIAA1123
AB032995	2.4e-08	25.3	KIAA1169

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR001696 272 291 PR00170 Na+ channel

IPR001696 307 320 PR00170 Na+ channel

HMMPfam IPR005821 79 289 PF00520 Ion transport

IPR000048 420 440 PF00612 IQ calmodulin-binding region

ProfileScan IPR000048 419 448 PS50096 IQ calmodulin-binding region

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR001696	272	291	PR00170	Na+ channel
IPR001696	307	320	PR00170	Na+ channel
HMMPfam	IPR005821	79	289	PF00520	Ion transport
IPR000048	420	440	PF00612	IQ calmodulin-binding region
ProfileScan	IPR000048	419	448	PS50096	IQ calmodulin-binding region

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 46 VFDISIMILICLNMVTMMVETD 67 SECONDARY 22

2 74 TLVLSRINLVFIVLFTGEFVLKL 96 PRIMARY 23

3 105 TIGWNIFDFVVVILSIVGMFLAE 127 PRIMARY 23

4 140 RVIRLARIGRILRLIKGAKGIRT 162 SECONDARY 23

5 167 LMMSLPALFNIGLLLFLVMFIYA 189 PRIMARY 23

6 268 FFFVSYIIISFLVVVNMYIAVIL 290 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	46	VFDISIMILICLNMVTMMVETD	67	SECONDARY	22
2	74	TLVLSRINLVFIVLFTGEFVLKL	96	PRIMARY	23
3	105	TIGWNIFDFVVVILSIVGMFLAE	127	PRIMARY	23
4	140	RVIRLARIGRILRLIKGAKGIRT	162	SECONDARY	23
5	167	LMMSLPALFNIGLLLFLVMFIYA	189	PRIMARY	23
6	268	FFFVSYIIISFLVVVNMYIAVIL	290	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: CATTTCACTTATTGGCCTCTG

Primer_r
: GTACTGCTTGGTGAATCATGC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 2

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: CATTTCACTTATTGGCCTCTG
Primer_r	: GTACTGCTTGGTGAATCATGC
PCR product length	: 161 bp
PCR conditions	: 95 °C15 sec62 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	2623 bp
Genome contig ID	gi89161199r_165552284
PolyA signal sequence (AATAAA,-21)	+--------+--------+----*----+---- CATAATTCTCCCATAATAAATTATATAAGGTGGCT
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AATTGGAATTCATTGGCTTCTTTCTGCTCAAGTCAATTTACACATCTACA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	2	r	165652284	165659222	3	99.1	Perfect prediction

Gene/Protein Characteristic Table for KIAA1356

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information