HUGE

Gene/Protein Characteristic Table for KIAA1215

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00769
Accession No. :	AB033041
Description :	Vang-like protein 2.
HUGO Gene Name :	vang-like 2 (van gogh, Drosophila) (VANGL2)
Clone Name :	fh01854 [Vector Info]
Flexi ORF Clone :	pF1KSDA1215
Source :	Human fetal brain

Features of the cloned DNA sequence	Description

Length: 5021 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 3293 bp

Genome contig ID gi89161185f_158552090
PolyA signal sequence
(AATAAA,-21)
+----*----+----*----+----*----+----
TTTTTTTTATATAAAATAAAGACATTTGACTTTTG
Flanking genome sequence
(112996 - 113045)
----+----*----+----*----+----*----+----*----+----*
TGGGGGCATTCTGTTGCTTTTCTTTCTTTACAGGAATGGGAGCAAATGAG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 1 f 158652090 158665084 7 99.3 Perfect prediction

Features of the protein sequence	Description

Length: 575 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
XP_001115459	0	99.8	vang-like 2 (va...	Macaca mulatta
Q9ULK5	5.8e-207	100.0	Vang-like prote...	Homo sapiens
XP_598791	1.9e-206	99.8	similar to Ltap...	Bos taurus
Q91ZD4	5.2e-206	99.4	Vang-like prote...	Mus musculus
BAF83670	6.9e-206	99.6	unnamed protein...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output)
No significant homologues
Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR009539 77 575 PF06638 Strabismus

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR009539	77	575	PF06638	Strabismus

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 164 AAGATLALLSFLTPLAFLLLPPL 186 PRIMARY 23

2 196 GTACEGLFISVAFKLLILLLGSW 218 PRIMARY 23

3 233 FVLRALLMVLVFLLVVSYWLFYG 255 PRIMARY 23

4 272 FAVSLVDALLFVHYLAVVLLELR 294 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	164	AAGATLALLSFLTPLAFLLLPPL	186	PRIMARY	23
2	196	GTACEGLFISVAFKLLILLLGSW	218	PRIMARY	23
3	233	FVLRALLMVLVFLLVVSYWLFYG	255	PRIMARY	23
4	272	FAVSLVDALLFVHYLAVVLLELR	294	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: CGTACTTCTCCTCCATTGGTC

Primer_r
: AATCTCACTTGGAAGGGACTC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 1

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: CGTACTTCTCCTCCATTGGTC
Primer_r	: AATCTCACTTGGAAGGGACTC
PCR product length	: 198 bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	3293 bp
Genome contig ID	gi89161185f_158552090
PolyA signal sequence (AATAAA,-21)	+--------+--------+----*----+---- TTTTTTTTATATAAAATAAAGACATTTGACTTTTG
Flanking genome sequence (112996 - 113045)	----+--------+--------+--------+--------+----* TGGGGGCATTCTGTTGCTTTTCTTTCTTTACAGGAATGGGAGCAAATGAG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	1	f	158652090	158665084	7	99.3	Perfect prediction

Gene/Protein Characteristic Table for KIAA1215

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information