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SpecieshumanProduct IDFHC01686Cloning SiteSgfI-PmeISymbolCASP8AP2
Alias : CED-4, FLASH, RIP25Descriptioncaspase 8 associated protein 2
Characterization of the cloned ORF
N-terminal HaloTag-fusions expressed in HEK293 visualized by HaloTag TMR ligand
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Length: 5943 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 1981 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
no hit
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) NP_036247 1982 606880 99.9 100.0 NP_001131139 1982 606880 99.9 100.0 NP_001131140 1982 606880 99.9 100.0 Inquiries or Suggestions ?
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Cloned ORF Nucleotide sequence for pFN21AA1315 Download>KIAA1315 5943 bp ATGGCAGCAGATGATGACAATGGTGATGGAACAAGTTTATTTGATGTCTTTTCTGCTTCT CCTCTTAAGAACAATGATGAAGGCTCACTGGACATATACGCTGGGTTGGACAGTGCTGTT TCTGACAGCGCTTCCAAATCCTGTGTACCATCAAGAAATTGTTTGGACTTATATGAAGAG ATCCTGACTGAAGAAGGAACTGCAAAGGAGGCAACATATAATGATTTGCAAGTAGAATAT GGAAAATGTCAACTACAAATGAAAGAGCTGATGAAAAAGTTTAAAGAAATACAGACACAG AATTTCAGCTTAATAAACGAAAACCAGTCTCTTAAGAAGAATATTTCAGCACTTATCAAA ACTGCCAGAGTGGAAATAAACCGCAAGGATGAAGAAATAAGTAATCTTCACCAAAGATTG TCTGAGTTTCCACATTTTCGAAATAATCATAAAACTGCAAGGACATTTGATACAGTTAAA ACAAAAGATCTTAAATCTAGATCTCCACATTTGGATGATTGTTCAAAGACTGATCACAGA GCTAAAAGTGATGTTTCTAAAGATGTACATCATAGCACTTCACTGCCAAATCTGGAAAAG GAAGGAAAACCACATTCTGATAAAAGGAGTACTTCACATTTACCTACATCTGTTGAGAAA CACTGCACTAATGGTGTTTGGTCACGTTCTCATTATCAGGTTGGCGAGGGTAGCTCAAAT GAGGATAGTAGAAGAGGAAGAAAAGATATTAGACATAGCCAGTTTAACAGAGGAACTGAA AGAGTACGAAAAGACTTAAGTACTGGCTGTGGTGATGGTGAACCAAGGATATTGGAGGCT AGTCAAAGGCTACAAGGACATCCTGAGAAATATGGTAAAGGTGAACCAAAGACTGAAAGC AAAAGTTCGAAGTTTAAAAGTAACTCAGATTCTGACTATAAAGGTGAACGCATTAACTCT TCTTGGGAGAAAGAGACCCCTGGAGAAAGGTCACACAGTCGAGTAGACTCTCAAAGTGAC AAAAAACTAGAAAGACAAAGTGAAAGATCACAAAATATAAATAGGAAAGAAGTTAAATCA CAAGACAAAGAAGAAAGAAAAGTTGATCAAAAACCTAAATCAGTAGTAAAGGACCAAGAC CACTGGAGAAGATCTGAACGAGCATCACTTCCTCATTCCAAGAATGAAATAACATTTTCT CATAATTCAAGTAAATACCATCTAGAAGAGAGAAGAGGATGGGAAGATTGTAAAAGAGAC AAGAGTGTAAACAGTCATAGTTTTCAAGATGGAAGATGTCCATCTTCTCTTTCAAACAGT AGAACTCACAAAAACATTGACTCTAAGGAAGTTGATGCCATGCATCAGTGGGAAAATACA CCTTTAAAAGCAGAAAGACATAGAACTGAAGATAAGAGGAAAAGAGAACAAGAAAGCAAA GAAGAAAATAGGCATATTAGAAATGAAAAAAGAGTACCTACAGAACATTTGCAGAAGACT AATAAGGAAACTAAGAAAACCACTACTGATTTAAAGAAACAGAATGAACCAAAGACTGAT AAGGGAGAAGTCCTTGATAATGGTGTTTCTGAAGGAGCAGATAATAAAGAGCTTGCAATG AAAGCTGAGAGTGGTCCAAATGAAACAAAAAACAAGGACCTAAAATTGAGTTTTATGAAA AAATTGAACTTAACTCTTTCTCCTGCTAAAAAGCAACCTGTTTCCCAGGATAATCAGCAT AAAATAACTGATATTCCCAAGTCCAGTGGTGTATGTGATTCAGAGTCTTCAATGCAAGTT AAAACAGTGGCATATGTTCCCTCCATAAGTGAACATATCTTGGGGGAAGCAGCTGTCAGT GAACATACCATGGGGGAAACCAAGTCAACGTTATTGGAACCAAAGGTTGCTCTTCTAGCA GTGACTGAACCCAGGATCGGTATCTCAGAAACCAACAAGGAAGACGAAAATAGTTTGTTA GTTAGGTCTGTTGACAATACTATGCATTGTGAAGAGCCCATTTGTGGTACAGAGACTTCC TTCCCATCTCCTATGGAAATACAACAGACAGAATCCTTGTTTCCATCAACAGGAATGAAA CAAACCATTAATAATGGAAGGGCAGCAGCTCCTGTGGTAATGGATGTATTACAAACAGAT GTGTCTCAAAACTTTGGCTTGGAATTGGATACCAAAAGAAATGATAATTCAGATTATTGT GGTATTTCTGAAGGTATGGAGATGAAGGTGGCACTTTCAACAACAGTGAGTGAAACCACT GAAAGCATTTTGCAGCCTTCAATTGAGGAAGCTGATATTTTGCCAATAATGCTTTCAGAA GATAATAACCCAAAATTTGAGCCTTCTGTTATAGTTACACCACTGGTTGAGAGTAAGTCG TGTCATCTGGAGCCTTGCTTACCTAAAGAGACTCTAGATTCTTCACTTCAGCAGACTGAG TTAATGGACCACAGAATGGCAACTGGTGAAACAAACTCAGTATATCATGATGATGATAAC TCGGTTTTGAGCATTGACCTTAATCACCTGAGACCTATTCCAGAAGCCATCAGTCCTCTG AATAGTCCAGTGAGACCTGTAGCAAAAGTTCTTAGAAATGAAAGCCCACCTCAAGTTCCA GTGTATAATAACAGTCATAAAGATGTGTTTTTACCAAATTCAGCTCATTCTACCTCTAAG AGTCAGTCTGATCTCAATAAGGAAAATCAAAAGCCAATTTACAAATCTGACAAATGTACA GAAGCAGACACATGTAAGAATTCACCATTAGATGAATTAGAAGAAGGAGAAATTAGAAGT GATAGTGAAACATCTAAACCACAAGAAAGTTTTGAAAAAAATTCCAAACGTAGAGTGTCA GCTGATGTGCGGAAGTCAAAGACTATCCCACGACGTGGGAAAAGTACTGTGTGTTTAGAT AAAGACAGTAGGAAAACACATGTAAGAATCCATCAGACCAATAACAAATGGAATAAAAGA CCTGATAAATCTAGCAGATCTTCAAAAACAGAGAAGAAAGATAAAGTGATGAGCACTTCC AGCTTGGAAAAAATAGTTCCAATTATTGCTGTACCCTCTTCTGAACAAGAGATCATGCAC ATGTTACGAATGATAAGAAAACATGTAAGAAAAAATTATATGAAATTCAAGGCAAAATTT TCATTAATACAATTTCACAGAATTATTGAGTCAGCAATTTTGAGTTTTACATCTTTAATT AAACATCTCAACTTACACAAAATCTCTAAGTCAGTGACTACCTTACAGAAGAATCTCTGT GATATTATAGAGTCTAAACTTAAGCAAGTTAAAAAGAATGGCATAGTTGATCGTTTATTT GAACAGCAACTACCAGATATGAAAAAAAAATTGTGGAAGTTTGTAGATGACCAACTTGAT TATTTGTTTGCAAAGCTTAAGAAAATCTTAGTATGTGATTCCAAAAGCTTTGGAAGAGAT AGTGATGAAGGCAAACTTGAAAAAACAAGTAAACAGAATGCACAGTATTCAAATAGTCAG AAAAGGAGTGTGGACAACTCCAACAGAGAATTGCTGAAAGAAAAATTATCAAAATCAGAA GACCCTGTTCATTATAAGTCTTTAGTGGGATGTAAAAAATCTGAGGAAAATTATCAAGAC CAAAATAACTCCAGTATTAACACTGTAAAGCATGACATTAAAAAAAATTTTAACATCTGC TTTGATAATATAAAGAACTCTCAATCCGAAGAGCGCTCCTTGGAAGTACACTGTCCAAGC ACCCCAAAGTCAGAAAAAAACGAAGGAAGCAGCATAGAGGATGCACAGACATCCCAGCAT GCAACTTTGAAGCCAGAACGAAGTTTCGAGATTCTTACCGAACAGCAAGCATCGAGCCTT ACTTTTAATTTAGTGAGTGATGCACAAATGGGTGAAATATTTAAAAGTTTGTTGCAAGGT TCTGATCTTTTAGACAGCAGTGTTAACTGTACTGAAAAAAGTGAGTGGGAGTTAAAGACT CCAGAGAAGCAGCTGCTAGAGACTCTTAAGTGCGAGTCTATACCAGCTTGTACAACAGAA GAGCTAGTTTCAGGGGTGGCTTCTCCATGTCCTAAAATGATTAGTGATGATAATTGGTCA TTATTATCATCTGAAAAAGGTCCATCTCTGTCTTCAGGGCTTTCATTGCCGGTTCATCCT GATGTGTTGGATGAAAGTTGTATGTTTGAAGTGTCTACTAACCTACCTTTAAGTAAAGAT AATGTGTGTAGTGTAGAAAAGAGCAAGCCCTGCGTTTCTTCCATACTTCTTGAAGATCTA GCAGTCTCTTTAACAGTACCATCGCCTCTGAAGTCAGATGGTCATCTCAGTTTTTTAAAG CCTGATATGTCGTCCAGTTCAACTCCTGAAGAAGTCATTAGTGCTCATTTTAGTGAAGAT GCCTTACTTGAGGAAGAGGATGCATCTGAGCAAGATATTCATTTAGCTCTGGAGTCTGAT AATTCAAGCAGTAAATCAAGTTGTTCTTCTTCCTGGACAAGCCGATCTGTTGCTCCAGGC TTTCAGTACCACCCTAATCTACCTATGCATGCTGTCATAATGGAAAAGTCCAATGATCAT TTCATTGTGAAAATACGACGTGCAACACCATCTACCTCTTCTGGCCTTAAACAGAGTATG ATGCCTGATGAATTATTGACATCTTTGCCCAGACATGGAAAGGAAGCTGATGAAGGACCA GAGAAAGAATATATTTCATGTCAGAACACAGTTTTTAAATCTGTGGAGGAATTGGAAAAC TCCAACAAAAATGTTGATGGCAGCAAGTCAACTCATGAAGAACAGAGCTCTATGATACAA ACACAGGTTCCTGATATATATGAATTTCTTAAAGATGCTTCAGATAAGATGGGTCATAGT GATGAAGTGGCTGATGAATGTTTCAAATTGCATCAAGTATGGGAAACAAAAGTGCCTGAA AGCATTGAAGAATTGCCTTCAATGGAAGAAATCTCACACTCTGTTGGGGAACATCTTCCA AACACATACGTAGATCTAACGAAAGATCCAGTCACTGAAACCAAAAACTTGGGGGAATTC ATAGAAGTAACAGTTTTACATATTGATCAGTTGGGATGTTCTGGAGGCAATTTAAATCAG AGTGCTCAAATATTAGACAATTCTTTGCAGGCTGATACTGTAGGTGCTTTTATTGATTTG ACACAAGATGCTTCAAGTGAGGCTAAAAGTGAAGGTAATCCTGCATTAGCTGTGGAAGAC TTGGGATGTGGGGTGATACAGGTAGATGAAGATAATTGTAAGGAAGAAAAGGCACAAGTG GCAAACAGGCCTTTAAAATGCATTGTTGAGGAAACCTATATCGACTTGACCACAGAATCT CCCAGTTCATGTGAAGTAAAAAAAGATGAGTTAAAATCAGAGCCAGGATCAAATTGTGAT AACTCGGAGTTGCCTGGGACTTTGCATAATTCTCACAAAAAGAGAAGAAACATTTCTGAT CTAAATCATCCTCATAAAAAACAAAGAAAGGAAACAGACTTAACTAATAAGGAAAAGACC AAGAAACCTACCCAAGATTCTTGTGAGAATACTGAAGCTCACCAAAAGAAAGCCAGTAAG AAGAAGGCCCCTCCTGTGACTAAAGATCCCTCATCATTAAAGGCAACCCCAGGGATTAAG GATTCATCAGCAGCACTTGCCACTTCTACAAGTCTTTCTGCAAAAAATGTTATTAAAAAG AAGGGAGAAATTATCATTTTATGGACAAGAAATGATGACCGGGAAATTTTATTGGAGTGT CAGAAAAGAGGGCCATCATTTAAAACATTTGCATATTTAGCCGCCAAGTTGGATAAAAAT CCAAATCAGGTCTCAGAAAGATTCCAGCAGCTAATGAAGCTCTTTGAAAAGTCAAAATGC AGG
Cloned ORF protein sequence for pFN21AA1315 Download>KIAA1315 1981 aa MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEE ILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIK TARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHR AKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSN EDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTES KSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKS QDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRD KSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESK EENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAM KAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQV KTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLL VRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTD VSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSE DNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDN SVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSK SQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVS ADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTS SLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLI KHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLD YLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSE DPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPS TPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQG SDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWS LLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDL AVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESD NSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSM MPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQ TQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLP NTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDL TQDASSEAKSEGNPALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTES PSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEKT KKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIKK KGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSKC R
Nucleotide Sequence (with vector) for pFN21AA1315 Download>pFN21AA1315 10648 bp TCAATATTGGCCATTAGCCATATTATTCATTGGTTATATAGCATAAATCAATATTGGCTA TTGGCCATTGCATACGTTGTATCTATATCATAATATGTACATTTATATTGGCTCATGTCC AATATGACCGCCATGTTGGCATTGATTATTGACTAGTTATTAATAGTAATCAATTACGGG GTCATTAGTTCATAGCCCATATATGGAGTTCCGCGTTACATAACTTACGGTAAATGGCCC GCCTGGCTGACCGCCCAACGACCCCCGCCCATTGACGTCAATAATGACGTATGTTCCCAT AGTAACGCCAATAGGGACTTTCCATTGACGTCAATGGGTGGAGTATTTACGGTAAACTGC CCACTTGGCAGTACATCAAGTGTATCATATGCCAAGTCCGCCCCCTATTGACGTCAATGA CGGTAAATGGCCCGCCTGGCATTATGCCCAGTACATGACCTTACGGGACTTTCCTACTTG GCAGTACATCTACGTATTAGTCATCGCTATTACCATGGTGATGCGGTTTTGGCAGTACAC CAATGGGCGTGGATAGCGGTTTGACTCACGGGGATTTCCAAGTCTCCACCCCATTGACGT CAATGGGAGTTTGTTTTGGCACCAAAATCAACGGGACTTTCCAAAATGTCGTAATAACCC CGCCCCGTTGACGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGC TGGTTTAGTGAACCGTCAGATCACTAGAAGCTTTATTGCGGTAGTTTATCACAGTTAAAT TGCTAACGCAGTCAGTGCTTCTGACACAACAGTCTCGAACTTAAGCTGCAGAAGTTGGTC GTGAGGCACTGGGCAGGTAAGTATCAAGGTTACAAGACAGGTTTAAGGAGACCAATAGAA ACTGGGCTTGTCGAGACAGAGAAGACTCTTGCGTTTCTGATAGGCACCTATTGGTCTTAC TGACATCCACTTTGCCTTTCTCTCCACAGGTGTCCACTCCCAGTTCAATTACAGCTCTTA AGGCTAGAGTATTAATACGACTCACTATAGGGCTAGCAAAGCCACCATGGCAGAAATCGG TACTGGCTTTCCATTCGACCCCCATTATGTGGAAGTCCTGGGCGAGCGCATGCACTACGT CGATGTTGGTCCGCGCGATGGCACCCCTGTGCTGTTCCTGCACGGTAACCCGACCTCCTC CTACGTGTGGCGCAACATCATCCCGCATGTTGCACCGACCCATCGCTGCATTGCTCCAGA CCTGATCGGTATGGGCAAATCCGACAAACCAGACCTGGGTTATTTCTTCGACGACCACGT CCGCTTCATGGATGCCTTCATCGAAGCCCTGGGTCTGGAAGAGGTCGTCCTGGTCATTCA CGACTGGGGCTCCGCTCTGGGTTTCCACTGGGCCAAGCGCAATCCAGAGCGCGTCAAAGG TATTGCATTTATGGAGTTCATCCGCCCTATCCCGACCTGGGACGAATGGCCAGAATTTGC CCGCGAGACCTTCCAGGCCTTCCGCACCACCGACGTCGGCCGCAAGCTGATCATCGATCA GAACGTTTTTATCGAGGGTACGCTGCCGATGGGTGTCGTCCGCCCGCTGACTGAAGTCGA GATGGACCATTACCGCGAGCCGTTCCTGAATCCTGTTGACCGCGAGCCACTGTGGCGCTT CCCAAACGAGCTGCCAATCGCCGGTGAGCCAGCGAACATCGTCGCGCTGGTCGAAGAATA CATGGACTGGCTGCACCAGTCCCCTGTCCCGAAGCTGCTGTTCTGGGGCACCCCAGGCGT TCTGATCCCACCGGCCGAAGCCGCTCGCCTGGCCAAAAGCCTGCCTAACTGCAAGGCTGT GGACATCGGCCCGGGTCTGAATCTGCTGCAAGAAGACAACCCGGACCTGATCGGCAGCGA GATCGCGCGCTGGCTGTCGACGCTCGAGATTTCCGGCGAGCCAACCACTGAGGATCTGTA CTTTCAGAGCGATAACGCGATCGCCATGGCAGCAGATGATGACAATGGTGATGGAACAAG TTTATTTGATGTCTTTTCTGCTTCTCCTCTTAAGAACAATGATGAAGGCTCACTGGACAT ATACGCTGGGTTGGACAGTGCTGTTTCTGACAGCGCTTCCAAATCCTGTGTACCATCAAG AAATTGTTTGGACTTATATGAAGAGATCCTGACTGAAGAAGGAACTGCAAAGGAGGCAAC ATATAATGATTTGCAAGTAGAATATGGAAAATGTCAACTACAAATGAAAGAGCTGATGAA AAAGTTTAAAGAAATACAGACACAGAATTTCAGCTTAATAAACGAAAACCAGTCTCTTAA GAAGAATATTTCAGCACTTATCAAAACTGCCAGAGTGGAAATAAACCGCAAGGATGAAGA AATAAGTAATCTTCACCAAAGATTGTCTGAGTTTCCACATTTTCGAAATAATCATAAAAC TGCAAGGACATTTGATACAGTTAAAACAAAAGATCTTAAATCTAGATCTCCACATTTGGA TGATTGTTCAAAGACTGATCACAGAGCTAAAAGTGATGTTTCTAAAGATGTACATCATAG CACTTCACTGCCAAATCTGGAAAAGGAAGGAAAACCACATTCTGATAAAAGGAGTACTTC ACATTTACCTACATCTGTTGAGAAACACTGCACTAATGGTGTTTGGTCACGTTCTCATTA TCAGGTTGGCGAGGGTAGCTCAAATGAGGATAGTAGAAGAGGAAGAAAAGATATTAGACA TAGCCAGTTTAACAGAGGAACTGAAAGAGTACGAAAAGACTTAAGTACTGGCTGTGGTGA TGGTGAACCAAGGATATTGGAGGCTAGTCAAAGGCTACAAGGACATCCTGAGAAATATGG TAAAGGTGAACCAAAGACTGAAAGCAAAAGTTCGAAGTTTAAAAGTAACTCAGATTCTGA CTATAAAGGTGAACGCATTAACTCTTCTTGGGAGAAAGAGACCCCTGGAGAAAGGTCACA CAGTCGAGTAGACTCTCAAAGTGACAAAAAACTAGAAAGACAAAGTGAAAGATCACAAAA TATAAATAGGAAAGAAGTTAAATCACAAGACAAAGAAGAAAGAAAAGTTGATCAAAAACC TAAATCAGTAGTAAAGGACCAAGACCACTGGAGAAGATCTGAACGAGCATCACTTCCTCA TTCCAAGAATGAAATAACATTTTCTCATAATTCAAGTAAATACCATCTAGAAGAGAGAAG AGGATGGGAAGATTGTAAAAGAGACAAGAGTGTAAACAGTCATAGTTTTCAAGATGGAAG ATGTCCATCTTCTCTTTCAAACAGTAGAACTCACAAAAACATTGACTCTAAGGAAGTTGA TGCCATGCATCAGTGGGAAAATACACCTTTAAAAGCAGAAAGACATAGAACTGAAGATAA GAGGAAAAGAGAACAAGAAAGCAAAGAAGAAAATAGGCATATTAGAAATGAAAAAAGAGT ACCTACAGAACATTTGCAGAAGACTAATAAGGAAACTAAGAAAACCACTACTGATTTAAA GAAACAGAATGAACCAAAGACTGATAAGGGAGAAGTCCTTGATAATGGTGTTTCTGAAGG AGCAGATAATAAAGAGCTTGCAATGAAAGCTGAGAGTGGTCCAAATGAAACAAAAAACAA GGACCTAAAATTGAGTTTTATGAAAAAATTGAACTTAACTCTTTCTCCTGCTAAAAAGCA ACCTGTTTCCCAGGATAATCAGCATAAAATAACTGATATTCCCAAGTCCAGTGGTGTATG TGATTCAGAGTCTTCAATGCAAGTTAAAACAGTGGCATATGTTCCCTCCATAAGTGAACA TATCTTGGGGGAAGCAGCTGTCAGTGAACATACCATGGGGGAAACCAAGTCAACGTTATT GGAACCAAAGGTTGCTCTTCTAGCAGTGACTGAACCCAGGATCGGTATCTCAGAAACCAA CAAGGAAGACGAAAATAGTTTGTTAGTTAGGTCTGTTGACAATACTATGCATTGTGAAGA GCCCATTTGTGGTACAGAGACTTCCTTCCCATCTCCTATGGAAATACAACAGACAGAATC CTTGTTTCCATCAACAGGAATGAAACAAACCATTAATAATGGAAGGGCAGCAGCTCCTGT GGTAATGGATGTATTACAAACAGATGTGTCTCAAAACTTTGGCTTGGAATTGGATACCAA AAGAAATGATAATTCAGATTATTGTGGTATTTCTGAAGGTATGGAGATGAAGGTGGCACT TTCAACAACAGTGAGTGAAACCACTGAAAGCATTTTGCAGCCTTCAATTGAGGAAGCTGA TATTTTGCCAATAATGCTTTCAGAAGATAATAACCCAAAATTTGAGCCTTCTGTTATAGT TACACCACTGGTTGAGAGTAAGTCGTGTCATCTGGAGCCTTGCTTACCTAAAGAGACTCT AGATTCTTCACTTCAGCAGACTGAGTTAATGGACCACAGAATGGCAACTGGTGAAACAAA CTCAGTATATCATGATGATGATAACTCGGTTTTGAGCATTGACCTTAATCACCTGAGACC TATTCCAGAAGCCATCAGTCCTCTGAATAGTCCAGTGAGACCTGTAGCAAAAGTTCTTAG AAATGAAAGCCCACCTCAAGTTCCAGTGTATAATAACAGTCATAAAGATGTGTTTTTACC AAATTCAGCTCATTCTACCTCTAAGAGTCAGTCTGATCTCAATAAGGAAAATCAAAAGCC AATTTACAAATCTGACAAATGTACAGAAGCAGACACATGTAAGAATTCACCATTAGATGA ATTAGAAGAAGGAGAAATTAGAAGTGATAGTGAAACATCTAAACCACAAGAAAGTTTTGA AAAAAATTCCAAACGTAGAGTGTCAGCTGATGTGCGGAAGTCAAAGACTATCCCACGACG TGGGAAAAGTACTGTGTGTTTAGATAAAGACAGTAGGAAAACACATGTAAGAATCCATCA GACCAATAACAAATGGAATAAAAGACCTGATAAATCTAGCAGATCTTCAAAAACAGAGAA GAAAGATAAAGTGATGAGCACTTCCAGCTTGGAAAAAATAGTTCCAATTATTGCTGTACC CTCTTCTGAACAAGAGATCATGCACATGTTACGAATGATAAGAAAACATGTAAGAAAAAA TTATATGAAATTCAAGGCAAAATTTTCATTAATACAATTTCACAGAATTATTGAGTCAGC AATTTTGAGTTTTACATCTTTAATTAAACATCTCAACTTACACAAAATCTCTAAGTCAGT GACTACCTTACAGAAGAATCTCTGTGATATTATAGAGTCTAAACTTAAGCAAGTTAAAAA GAATGGCATAGTTGATCGTTTATTTGAACAGCAACTACCAGATATGAAAAAAAAATTGTG GAAGTTTGTAGATGACCAACTTGATTATTTGTTTGCAAAGCTTAAGAAAATCTTAGTATG TGATTCCAAAAGCTTTGGAAGAGATAGTGATGAAGGCAAACTTGAAAAAACAAGTAAACA GAATGCACAGTATTCAAATAGTCAGAAAAGGAGTGTGGACAACTCCAACAGAGAATTGCT GAAAGAAAAATTATCAAAATCAGAAGACCCTGTTCATTATAAGTCTTTAGTGGGATGTAA AAAATCTGAGGAAAATTATCAAGACCAAAATAACTCCAGTATTAACACTGTAAAGCATGA CATTAAAAAAAATTTTAACATCTGCTTTGATAATATAAAGAACTCTCAATCCGAAGAGCG CTCCTTGGAAGTACACTGTCCAAGCACCCCAAAGTCAGAAAAAAACGAAGGAAGCAGCAT AGAGGATGCACAGACATCCCAGCATGCAACTTTGAAGCCAGAACGAAGTTTCGAGATTCT TACCGAACAGCAAGCATCGAGCCTTACTTTTAATTTAGTGAGTGATGCACAAATGGGTGA AATATTTAAAAGTTTGTTGCAAGGTTCTGATCTTTTAGACAGCAGTGTTAACTGTACTGA AAAAAGTGAGTGGGAGTTAAAGACTCCAGAGAAGCAGCTGCTAGAGACTCTTAAGTGCGA GTCTATACCAGCTTGTACAACAGAAGAGCTAGTTTCAGGGGTGGCTTCTCCATGTCCTAA AATGATTAGTGATGATAATTGGTCATTATTATCATCTGAAAAAGGTCCATCTCTGTCTTC AGGGCTTTCATTGCCGGTTCATCCTGATGTGTTGGATGAAAGTTGTATGTTTGAAGTGTC TACTAACCTACCTTTAAGTAAAGATAATGTGTGTAGTGTAGAAAAGAGCAAGCCCTGCGT TTCTTCCATACTTCTTGAAGATCTAGCAGTCTCTTTAACAGTACCATCGCCTCTGAAGTC AGATGGTCATCTCAGTTTTTTAAAGCCTGATATGTCGTCCAGTTCAACTCCTGAAGAAGT CATTAGTGCTCATTTTAGTGAAGATGCCTTACTTGAGGAAGAGGATGCATCTGAGCAAGA TATTCATTTAGCTCTGGAGTCTGATAATTCAAGCAGTAAATCAAGTTGTTCTTCTTCCTG GACAAGCCGATCTGTTGCTCCAGGCTTTCAGTACCACCCTAATCTACCTATGCATGCTGT CATAATGGAAAAGTCCAATGATCATTTCATTGTGAAAATACGACGTGCAACACCATCTAC CTCTTCTGGCCTTAAACAGAGTATGATGCCTGATGAATTATTGACATCTTTGCCCAGACA TGGAAAGGAAGCTGATGAAGGACCAGAGAAAGAATATATTTCATGTCAGAACACAGTTTT TAAATCTGTGGAGGAATTGGAAAACTCCAACAAAAATGTTGATGGCAGCAAGTCAACTCA TGAAGAACAGAGCTCTATGATACAAACACAGGTTCCTGATATATATGAATTTCTTAAAGA TGCTTCAGATAAGATGGGTCATAGTGATGAAGTGGCTGATGAATGTTTCAAATTGCATCA AGTATGGGAAACAAAAGTGCCTGAAAGCATTGAAGAATTGCCTTCAATGGAAGAAATCTC ACACTCTGTTGGGGAACATCTTCCAAACACATACGTAGATCTAACGAAAGATCCAGTCAC TGAAACCAAAAACTTGGGGGAATTCATAGAAGTAACAGTTTTACATATTGATCAGTTGGG ATGTTCTGGAGGCAATTTAAATCAGAGTGCTCAAATATTAGACAATTCTTTGCAGGCTGA TACTGTAGGTGCTTTTATTGATTTGACACAAGATGCTTCAAGTGAGGCTAAAAGTGAAGG TAATCCTGCATTAGCTGTGGAAGACTTGGGATGTGGGGTGATACAGGTAGATGAAGATAA TTGTAAGGAAGAAAAGGCACAAGTGGCAAACAGGCCTTTAAAATGCATTGTTGAGGAAAC CTATATCGACTTGACCACAGAATCTCCCAGTTCATGTGAAGTAAAAAAAGATGAGTTAAA ATCAGAGCCAGGATCAAATTGTGATAACTCGGAGTTGCCTGGGACTTTGCATAATTCTCA CAAAAAGAGAAGAAACATTTCTGATCTAAATCATCCTCATAAAAAACAAAGAAAGGAAAC AGACTTAACTAATAAGGAAAAGACCAAGAAACCTACCCAAGATTCTTGTGAGAATACTGA AGCTCACCAAAAGAAAGCCAGTAAGAAGAAGGCCCCTCCTGTGACTAAAGATCCCTCATC ATTAAAGGCAACCCCAGGGATTAAGGATTCATCAGCAGCACTTGCCACTTCTACAAGTCT TTCTGCAAAAAATGTTATTAAAAAGAAGGGAGAAATTATCATTTTATGGACAAGAAATGA TGACCGGGAAATTTTATTGGAGTGTCAGAAAAGAGGGCCATCATTTAAAACATTTGCATA TTTAGCCGCCAAGTTGGATAAAAATCCAAATCAGGTCTCAGAAAGATTCCAGCAGCTAAT GAAGCTCTTTGAAAAGTCAAAATGCAGGGTTTAAACGAATTCGGGCTCGGTACCCGGGGA TCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGATCCGGCTGCTAACAAAGCCCGAAAGG AAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATAACCCCTTGGGGCGGCCG CTTCGAGCAGACATGATAAGATACATTGATGAGTTTGGACAAACCACAACTAGAATGCAG TGAAAAAAATGCTTTATTTGTGAAATTTGTGATGCTATTGCTTTATTTGTAACCATTATA AGCTGCAATAAACAAGTTAACAACAACAATTGCATTCATTTTATGTTTCAGGTTCAGGGG GAGATGTGGGAGGTTTTTTTAAGCAAGTAAAACCTCTACAAATGTGGTAAAATCGAATTC TAATGGATCCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCAGTAGCTGACATTC ATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTAATGGTTTCTTAGACGTCA GGTGGCACTTTTCGGGGAAATGTGCGCGGAACCCCTATTTGTTTATTTTTCTAAATACAT TCAAATATGTATCCGCTCATGAGACAATAACCCTGATAAATGCTTCAATAATATTGAAAA AGGAAGAGTATGAGTATTCAACATTTCCGTGTCGCCCTTATTCCCTTTTTTGCGGCATTT TGCCTTCCTGTTTTTGCTCACCCAGAAACGCTGGTGAAAGTAAAAGATGCTGAAGATCAG TTGGGTGCACGAGTGGGTTACATCGAACTGGATCTCAACAGCGGTAAGATCCTTGAGAGT TTTCGCCCCGAAGAACGTTTTCCAATGATGAGCACTTTCAAAGTTCTGCTATGTGGCGCG GTATTATCCCGTATTGACGCCGGGCAAGAGCAACTCGGTCGCCGCATACACTATTCTCAG AATGACTTGGTTGAGTACTCACCAGTCACAGAAAAGCATCTTACGGATGGCATGACAGTA AGAGAATTATGCAGTGCTGCCATAACCATGAGTGATAACACTGCGGCCAACTTACTTCTG ACAACTATCGGAGGACCGAAGGAGCTAACCGCTTTTTTGCACAACATGGGGGATCATGTA ACTCGCCTTGATCGTTGGGAACCGGAGCTGAATGAAGCCATACCAAACGACGAGCGTGAC ACCACGATGCCTGTAGCAATGGCAACAACGTTGCGCAAACTATTAACTGGCGAACTACTT ACTCTAGCTTCCCGGCAACAATTAATAGACTGGATGGAGGCGGATAAAGTTGCAGGACCA CTTCTGCGCTCGGCCCTTCCGGCTGGCTGGTTTATTGCTGATAAATCTGGAGCCGGTGAG CGTGGGTCTCGCGGTATCATTGCAGCACTGGGGCCAGATGGTAAGCCCTCCCGTATCGTA GTTATCTACACGACGGGGAGTCAGGCAACTATGGATGAACGAAATAGACAGATCGCTGAG ATAGGTGCCTCACTGATTAAGCATTGGTAATTCGAAATGACCGACCAAGCGACGCCCAAC CGGTATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATCAGGGGATAACGCAG GAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGC TGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTC AGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCC TCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTT CGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCG TTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTAT CCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGCAG CCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTTCTTGAAGT GGTGGCCTAACTACGGCTACACTAGAAGGACAGTATTTGGTATCTGCGCTCTGCTGAAGC CAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTA GCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGATTTCAAGAAG ATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGGGA TTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTATAGTCCGGAAATA CAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAATGGCAGCTT CAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTATTCATACGG TTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCATTTTTACCT GTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGGGATTATGG TAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTCCGGCCACG ATGCGTCCGGCGTAGAGGATCGAGATCT
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