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SpecieshumanProduct IDFXC01017Cloning SiteSgfI-PmeIGeneKIBB1467SymbolPIK3C2B
Alias : C2-PI3KDescriptionphosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 betaOriginal Clone IDfg04853
Length: 4902 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 1634 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS1446.1 0 100.0 PIK3C2B CCDS7824.1 6.7e-148 47.2 PIK3C2A CCDS44839.1 2.3e-79 37.4 PIK3C2G CCDS73452.1 2.4e-79 38.5 PIK3C2G CCDS43171.1 3.7e-43 34.7 PIK3CA
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition HMMPfam IPR000341 365 465 PF00794 Phosphoinositide 3-kinase IPR002420 649 787 PF00792 Phosphoinositide 3-kinase IPR001263 812 988 PF00613 Phosphoinositide 3-kinase IPR000403 1078 1290 PF00454 Phosphatidylinositol 3-/4-kinase IPR001683 1367 1476 PF00787 Phox homologous domain IPR000008 1520 1607 PF00168 C2 calcium-dependent membrane targeting HMMSmart IPR000341 364 466 SM00144 Phosphoinositide 3-kinase IPR002420 619 728 SM00142 Phosphoinositide 3-kinase IPR001263 805 991 SM00145 Phosphoinositide 3-kinase IPR000403 1079 1341 SM00146 Phosphatidylinositol 3-/4-kinase IPR001683 1365 1477 SM00312 Phox homologous domain IPR000008 1518 1623 SM00239 C2 calcium-dependent membrane targeting ProfileScan IPR000403 1078 1342 PS50290 Phosphatidylinositol 3-/4-kinase IPR001683 1365 1481 PS50195 Phox homologous domain IPR018029 1517 1608 PS50004 C2 membrane targeting protein
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) XP_016856963 1634 602838 100.0 100.0 XP_011507933 1634 602838 100.0 100.0 XP_011507932 1634 602838 100.0 100.0 XP_016856962 1634 602838 100.0 100.0 XP_005245314 1634 602838 100.0 100.0 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KSDB1467 Download>KIBB1467 4902 bp ATGTCTTCGACTCAGGGCAATGGGGAACACTGGAAGTCCCTGGAGTCAGTGGGCATCAGC CGCAAAGAGCTAGCGATGGCCGAAGCCCTGCAGATGGAGTATGATGCCCTGTCCCGGCTC CGGCATGACAAGGAGGAGAACAGAGCCAAGCAGAACGCAGACCCCTCTCTCATCAGCTGG GATGAGCCTGGGGTAGACTTTTACAGCAAGCCAGCAGGAAGGCGGACCGACCTCAAGCTG TTACGCGGTCTCTCTGGCTCTGATCCTACCCTTAACTACAACTCACTATCCCCACAGGAA GGGCCGCCCAACCACTCTACCTCCCAAGGGCCACAGCCTGGCTCAGATCCCTGGCCCAAA GGCTCCCTGTCTGGAGACTATCTCTACATTTTTGATGGTTCAGATGGGGGAGTCTCTTCG TCCCCAGGACCAGGGGACATAGAGGGCTCTTGCAAGAAACTATCCCCACCTCCTCTGCCT CCCCGAGCTTCTATCTGGGATACCCCTCCCCTGCCTCCCAGAAAGGGGTCCCCCTCATCC TCCAAGATCTCCCAGCCCAGTGACATCAACACTTTCTCTTTGGTCGAACAATTGCCAGGC AAACTGCTAGAGCATCGGATCCTAGAAGAGGAAGAGGTGCTGGGAGGTGGGGGTCAGGGG CGCCTACTGGGGTCTGTGGACTATGATGGTATCAATGATGCAATTACTAGGCTCAACTTG AAATCGACCTATGATGCGGAGATGTTGCGGGATGCCACCAGGGGCTGGAAGGAGGGCCGA GGGCCGCTGGACTTCAGCAAAGACACCTCTGGAAAACCCGTGGCCAGGAGCAAGACTATG CCCCCTCAGGTGCCCCCCCGCACCTATGCCTCCCGCTATGGCAACCGAAAGAATGCGACG CCTGGCAAGAACCGCCGGATTTCTGCAGCCCCGGTGGGCTCCCGGCCCCACACTGTTGCC AATGGCCATGAGTTGTTTGAGGTCTCAGAAGAGAGAGATGAGGAGGTTGCTGCATTTTGC CACATGCTGGATATCCTTCGATCTGGCTCTGACATCCAAGACTACTTCCTCACTGGCTAT GTCTGGAGTGCTGTCACCCCTAGCCCAGAGCACCTCGGGGATGAGGTCAACCTGAAGGTG ACTGTGTTGTGTGACAGGCTTCAAGAGGCACTCACTTTCACCTGCAACTGTTCCTCCACT GTAGACTTGCTTATCTACCAGACCCTGTGCTACACCCATGATGACCTGAGGAATGTGGAC GTGGGTGACTTTGTGCTAAAGCCCTGCGGGCTGGAGGAGTTCCTGCAGAACAAGCATGCC TTGGGCAGTCATGAGTACATCCAATACTGCCGCAAGTTTGACATTGACATTCGGCTACAG CTGATGGAGCAGAAGGTTGTGCGCAGTGACCTGGCCCGGACGGTGAATGATGACCAGAGC CCCTCCACCTTGAACTACCTCGTCCATCTCCAAGAGAGGCCTGTCAAGCAGACCATCAGC AGGCAGGCCCTGAGTCTTCTGTTCGACACTTACCACAATGAGGTGGATGCCTTCCTGCTG GCTGATGGAGACTTCCCACTGAAGGCTGACAGGGTGGTCCAGTCCGTCAAGGCCATCTGC AACGCCCTGGCCGCCGTGGAAACCCCTGAGATCACCAGTGCTCTCAACCAGCTGCCCCCC TGCCCCTCCCGCATGCAGCCTAAAATTCAGAAGGATCCCAGTGTCTTGGCTGTGAGGGAA AACCGAGAGAAGGTCGTGGAAGCCCTGACCGCTGCCATCTTGGACCTGGTGGAGCTGTAC TGCAACACATTCAACGCAGACTTCCAGACGGCAGTGCCCGGGAGCCGCAAGCATGACCTG GTCCAGGAGGCCTGCCATTTCGCCAGGTCCCTGGCCTTCACTGTCTATGCCACCCACCGC ATCCCCATCATCTGGGCTACCAGCTATGAAGATTTCTACCTCTCCTGCTCCCTCAGCCAT GGCGGCAAGGAGCTGTGCAGCCCCCTGCAGACCCGAAGAGCTCACTTCTCCAAGTACCTC TTCCACCTCATCGTCTGGGACCAGCAGATCTGCTTCCCAGTGCAGGTGAACCGGCTGCCT CGGGAGACACTGCTGTGTGCCACTCTCTATGCTCTGCCCATCCCCCCACCGGGGAGCTCC TCAGAGGCCAATAAGCAGCGGCGGGTGCCTGAAGCCCTGGGCTGGGTCACTACCCCACTC TTCAACTTCAGGCAGGTCCTGACCTGTGGCCGGAAGCTTCTGGGTTTGTGGCCAGCAACA CAGGAAAATCCCAGCGCCCGTTGGAGTGCACCTAATTTCCACCAGCCAGACAGTGTCATC CTGCAGATTGACTTCCCCACCTCGGCCTTTGACATCAAGTTCACCAGCCCCCCTGGAGAC AAGTTCAGCCCCCGCTATGAGTTTGGCAGCCTCCGGGAAGAAGACCAGCGCAAGCTTAAA GACATCATGCAGAAAGAGTCCTTGTACTGGCTCACTGATGCTGACAAGAAGCGCCTGTGG GAGAAGCGATATTACTGCCACTCGGAGGTGAGCTCGCTCCCCCTGGTGCTCGCCAGCGCC CCCAGCTGGGAGTGGGCTTGCCTGCCTGACATCTATGTTCTCCTGAAGCAGTGGACCCAC ATGAACCACCAGGATGCCCTGGGGCTCCTGCATGCCACCTTCCCGGACCAGGAGGTGCGT CGTATGGCTGTGCAGTGGATTGGCTCACTCTCAGATGCTGAGCTGCTAGACTACCTGCCC CAGCTGGTACAGGCCCTGAAGTATGAATGCTACCTGGACAGCCCGTTGGTGCGCTTCCTC CTGAAACGAGCTGTGTCTGACTTGAGAGTGACTCACTACTTCTTCTGGTTACTGAAGGAC GGCCTCAAGGACTCTCAGTTCAGCATCCGCTACCAGTATCTGCTGGCAGCCTTACTGTGC TGCTGTGGCAAGGGGCTGAGAGAAGAGTTTAACCGCCAGTGCTGGCTTGTCAATGCCCTG GCCAAACTGGCCCAGCAGGTCCGGGAGGCAGCCCCATCTGCAAGGCAGGGAATCCTCCGC ACGGGCCTGGAGGAGGTGAAGCAGTTCTTTGCCCTCAATGGCTCGTGCCGCTTGCCACTC AGCCCCAGTCTGCTGGTTAAGGGAATTGTGCCCAGGGACTGTTCCTACTTCAACTCCAAT GCTGTCCCCCTCAAACTCTCCTTCCAAAATGTGGATCCCCTGGGTGAGAACATCCGTGTC ATCTTCAAGTGTGGGGACGACCTTCGCCAGGACATGCTAACGCTGCAGATGATTCGCATC ATGAGCAAGATCTGGGTCCAGGAGGGGCTGGACATGCGCATGGTCATCTTCCGCTGCTTC TCCACCGGCCGGGGCAGAGGGATGGTGGAGATGATCCCTAATGCTGAGACCCTGCGTAAG ATCCAGGTGGAGCATGGGGTGACCGGCTCGTTCAAGGACCGGCCCCTGGCAGACTGGCTG CAGAAACACAACCCTGGGGAGGACGAGTATGAGAAGGCTGTGGAGAACTTTATCTACTCC TGCGCTGGCTGCTGCGTGGCCACGTACGTCTTGGGCATCTGTGACCGACATAATGACAAC ATCATGCTGAAGACCACTGGTCACATGTTCCACATTGATTTTGGCCGCTTCCTGGGCCAT GCCCAGATGTTTGGCAACATCAAGCGGGACCGTGCCCCCTTTGTCTTCACCTCGGACATG GCGTATGTCATCAACGGGGGTGACAAGCCTTCCAGCCGCTTCCATGATTTTGTTGACCTT TGCTGCCAAGCCTACAACCTCATTCGCAAGCACACCCACCTCTTCCTCAACCTTCTGGGC CTGATGTTGTCCTGTGGGATCCCTGAACTCTCAGACCTGGAGGACCTCAAGTATGTGTAC GATGCCCTGAGGCCTCAGGATACAGAGGCCAATGCCACTACCTACTTCACTAGGTTGATT GAGTCCAGCCTGGGCAGTGTAGCCACAAAGCTCAATTTTTTCATCCATAATCTGGCTCAG ATGAAGTTCACGGGCTCAGATGACCGGCTGACCCTCTCCTTTGCCTCCCGAACACACACT CTCAAGAGCTCTGGCCGAATCAGTGATGTTTTCCTCTGCCGCCATGAGAAGATCTTCCAC CCCAACAAAGGCTATATATATGTGGTAAAGGTGATGCGAGAGAACACTCACGAGGCCACC TACATCCAGCGGACCTTTGAGGAGTTCCAGGAATTACACAATAAGTTGCGGCTGCTCTTC CCTTCTTCCCACTTGCCCAGCTTCCCTAGTCGCTTCGTGATCGGCCGCTCCCGGGGAGAG GCGGTGGCCGAGCGGCGGAGGGAGGAGCTAAACGGTTACATCTGGCACTTGATCCACGCA CCCCCTGAGGTGGCCGAGTGTGATTTGGTGTACACCTTCTTCCACCCACTGCCCCGGGAT GAGAAGGCTATGGGCACCAGCCCAGCTCCTAAGTCCTCAGATGGCACATGGGCCCGGCCC GTCGGAAAGGTGGGAGGGGAGGTGAAGCTGTCCATCTCCTACAAAAACAATAAACTCTTC ATCATGGTGATGCATATTCGGGGCTTGCAACTGCTCCAGGATGGAAATGACCCTGACCCC TATGTGAAAATTTACCTCCTTCCTGACCCTCAGAAAACCACTAAGAGGAAAACCAAAGTG GCCCGGAAAACCTGCAATCCTACCTACAATGAGATGTTGGTATATGATGGGATCCCCAAG GGTGACCTGCAGCAGCGGGAGCTCCAGCTGAGCGTGCTGAGTGAGCAGGGATTCTGGGAG AACGTCCTCCTCGGTGAGGTGAACATCCGCCTGCGAGAGCTGGACCTGGCTCAGGAGAAG ACCGGCTGGTTCGCCCTGGGATCTCGAAGTCATGGCACCTTG
Cloned ORF protein sequence for pF1KSDB1467 Download>KIBB1467 1634 aa MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHDKEENRAKQNADPSLISW DEPGVDFYSKPAGRRTDLKLLRGLSGSDPTLNYNSLSPQEGPPNHSTSQGPQPGSDPWPK GSLSGDYLYIFDGSDGGVSSSPGPGDIEGSCKKLSPPPLPPRASIWDTPPLPPRKGSPSS SKISQPSDINTFSLVEQLPGKLLEHRILEEEEVLGGGGQGRLLGSVDYDGINDAITRLNL KSTYDAEMLRDATRGWKEGRGPLDFSKDTSGKPVARSKTMPPQVPPRTYASRYGNRKNAT PGKNRRISAAPVGSRPHTVANGHELFEVSEERDEEVAAFCHMLDILRSGSDIQDYFLTGY VWSAVTPSPEHLGDEVNLKVTVLCDRLQEALTFTCNCSSTVDLLIYQTLCYTHDDLRNVD VGDFVLKPCGLEEFLQNKHALGSHEYIQYCRKFDIDIRLQLMEQKVVRSDLARTVNDDQS PSTLNYLVHLQERPVKQTISRQALSLLFDTYHNEVDAFLLADGDFPLKADRVVQSVKAIC NALAAVETPEITSALNQLPPCPSRMQPKIQKDPSVLAVRENREKVVEALTAAILDLVELY CNTFNADFQTAVPGSRKHDLVQEACHFARSLAFTVYATHRIPIIWATSYEDFYLSCSLSH GGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLYALPIPPPGSS SEANKQRRVPEALGWVTTPLFNFRQVLTCGRKLLGLWPATQENPSARWSAPNFHQPDSVI LQIDFPTSAFDIKFTSPPGDKFSPRYEFGSLREEDQRKLKDIMQKESLYWLTDADKKRLW EKRYYCHSEVSSLPLVLASAPSWEWACLPDIYVLLKQWTHMNHQDALGLLHATFPDQEVR RMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHYFFWLLKD GLKDSQFSIRYQYLLAALLCCCGKGLREEFNRQCWLVNALAKLAQQVREAAPSARQGILR TGLEEVKQFFALNGSCRLPLSPSLLVKGIVPRDCSYFNSNAVPLKLSFQNVDPLGENIRV IFKCGDDLRQDMLTLQMIRIMSKIWVQEGLDMRMVIFRCFSTGRGRGMVEMIPNAETLRK IQVEHGVTGSFKDRPLADWLQKHNPGEDEYEKAVENFIYSCAGCCVATYVLGICDRHNDN IMLKTTGHMFHIDFGRFLGHAQMFGNIKRDRAPFVFTSDMAYVINGGDKPSSRFHDFVDL CCQAYNLIRKHTHLFLNLLGLMLSCGIPELSDLEDLKYVYDALRPQDTEANATTYFTRLI ESSLGSVATKLNFFIHNLAQMKFTGSDDRLTLSFASRTHTLKSSGRISDVFLCRHEKIFH PNKGYIYVVKVMRENTHEATYIQRTFEEFQELHNKLRLLFPSSHLPSFPSRFVIGRSRGE AVAERRREELNGYIWHLIHAPPEVAECDLVYTFFHPLPRDEKAMGTSPAPKSSDGTWARP VGKVGGEVKLSISYKNNKLFIMVMHIRGLQLLQDGNDPDPYVKIYLLPDPQKTTKRKTKV ARKTCNPTYNEMLVYDGIPKGDLQQRELQLSVLSEQGFWENVLLGEVNIRLRELDLAQEK TGWFALGSRSHGTL
Nucleotide Sequence (with vector) for pF1KSDB1467 Download>pF1KSDB1467 8039 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCTTTCGAAGGAGAT AGAACCATGTCTTCGACTCAGGGCAATGGGGAACACTGGAAGTCCCTGGAGTCAGTGGGC ATCAGCCGCAAAGAGCTAGCGATGGCCGAAGCCCTGCAGATGGAGTATGATGCCCTGTCC CGGCTCCGGCATGACAAGGAGGAGAACAGAGCCAAGCAGAACGCAGACCCCTCTCTCATC AGCTGGGATGAGCCTGGGGTAGACTTTTACAGCAAGCCAGCAGGAAGGCGGACCGACCTC AAGCTGTTACGCGGTCTCTCTGGCTCTGATCCTACCCTTAACTACAACTCACTATCCCCA CAGGAAGGGCCGCCCAACCACTCTACCTCCCAAGGGCCACAGCCTGGCTCAGATCCCTGG CCCAAAGGCTCCCTGTCTGGAGACTATCTCTACATTTTTGATGGTTCAGATGGGGGAGTC TCTTCGTCCCCAGGACCAGGGGACATAGAGGGCTCTTGCAAGAAACTATCCCCACCTCCT CTGCCTCCCCGAGCTTCTATCTGGGATACCCCTCCCCTGCCTCCCAGAAAGGGGTCCCCC TCATCCTCCAAGATCTCCCAGCCCAGTGACATCAACACTTTCTCTTTGGTCGAACAATTG CCAGGCAAACTGCTAGAGCATCGGATCCTAGAAGAGGAAGAGGTGCTGGGAGGTGGGGGT CAGGGGCGCCTACTGGGGTCTGTGGACTATGATGGTATCAATGATGCAATTACTAGGCTC AACTTGAAATCGACCTATGATGCGGAGATGTTGCGGGATGCCACCAGGGGCTGGAAGGAG GGCCGAGGGCCGCTGGACTTCAGCAAAGACACCTCTGGAAAACCCGTGGCCAGGAGCAAG ACTATGCCCCCTCAGGTGCCCCCCCGCACCTATGCCTCCCGCTATGGCAACCGAAAGAAT GCGACGCCTGGCAAGAACCGCCGGATTTCTGCAGCCCCGGTGGGCTCCCGGCCCCACACT GTTGCCAATGGCCATGAGTTGTTTGAGGTCTCAGAAGAGAGAGATGAGGAGGTTGCTGCA TTTTGCCACATGCTGGATATCCTTCGATCTGGCTCTGACATCCAAGACTACTTCCTCACT GGCTATGTCTGGAGTGCTGTCACCCCTAGCCCAGAGCACCTCGGGGATGAGGTCAACCTG AAGGTGACTGTGTTGTGTGACAGGCTTCAAGAGGCACTCACTTTCACCTGCAACTGTTCC TCCACTGTAGACTTGCTTATCTACCAGACCCTGTGCTACACCCATGATGACCTGAGGAAT GTGGACGTGGGTGACTTTGTGCTAAAGCCCTGCGGGCTGGAGGAGTTCCTGCAGAACAAG CATGCCTTGGGCAGTCATGAGTACATCCAATACTGCCGCAAGTTTGACATTGACATTCGG CTACAGCTGATGGAGCAGAAGGTTGTGCGCAGTGACCTGGCCCGGACGGTGAATGATGAC CAGAGCCCCTCCACCTTGAACTACCTCGTCCATCTCCAAGAGAGGCCTGTCAAGCAGACC ATCAGCAGGCAGGCCCTGAGTCTTCTGTTCGACACTTACCACAATGAGGTGGATGCCTTC CTGCTGGCTGATGGAGACTTCCCACTGAAGGCTGACAGGGTGGTCCAGTCCGTCAAGGCC ATCTGCAACGCCCTGGCCGCCGTGGAAACCCCTGAGATCACCAGTGCTCTCAACCAGCTG CCCCCCTGCCCCTCCCGCATGCAGCCTAAAATTCAGAAGGATCCCAGTGTCTTGGCTGTG AGGGAAAACCGAGAGAAGGTCGTGGAAGCCCTGACCGCTGCCATCTTGGACCTGGTGGAG CTGTACTGCAACACATTCAACGCAGACTTCCAGACGGCAGTGCCCGGGAGCCGCAAGCAT GACCTGGTCCAGGAGGCCTGCCATTTCGCCAGGTCCCTGGCCTTCACTGTCTATGCCACC CACCGCATCCCCATCATCTGGGCTACCAGCTATGAAGATTTCTACCTCTCCTGCTCCCTC AGCCATGGCGGCAAGGAGCTGTGCAGCCCCCTGCAGACCCGAAGAGCTCACTTCTCCAAG TACCTCTTCCACCTCATCGTCTGGGACCAGCAGATCTGCTTCCCAGTGCAGGTGAACCGG CTGCCTCGGGAGACACTGCTGTGTGCCACTCTCTATGCTCTGCCCATCCCCCCACCGGGG AGCTCCTCAGAGGCCAATAAGCAGCGGCGGGTGCCTGAAGCCCTGGGCTGGGTCACTACC CCACTCTTCAACTTCAGGCAGGTCCTGACCTGTGGCCGGAAGCTTCTGGGTTTGTGGCCA GCAACACAGGAAAATCCCAGCGCCCGTTGGAGTGCACCTAATTTCCACCAGCCAGACAGT GTCATCCTGCAGATTGACTTCCCCACCTCGGCCTTTGACATCAAGTTCACCAGCCCCCCT GGAGACAAGTTCAGCCCCCGCTATGAGTTTGGCAGCCTCCGGGAAGAAGACCAGCGCAAG CTTAAAGACATCATGCAGAAAGAGTCCTTGTACTGGCTCACTGATGCTGACAAGAAGCGC CTGTGGGAGAAGCGATATTACTGCCACTCGGAGGTGAGCTCGCTCCCCCTGGTGCTCGCC AGCGCCCCCAGCTGGGAGTGGGCTTGCCTGCCTGACATCTATGTTCTCCTGAAGCAGTGG ACCCACATGAACCACCAGGATGCCCTGGGGCTCCTGCATGCCACCTTCCCGGACCAGGAG GTGCGTCGTATGGCTGTGCAGTGGATTGGCTCACTCTCAGATGCTGAGCTGCTAGACTAC CTGCCCCAGCTGGTACAGGCCCTGAAGTATGAATGCTACCTGGACAGCCCGTTGGTGCGC TTCCTCCTGAAACGAGCTGTGTCTGACTTGAGAGTGACTCACTACTTCTTCTGGTTACTG AAGGACGGCCTCAAGGACTCTCAGTTCAGCATCCGCTACCAGTATCTGCTGGCAGCCTTA CTGTGCTGCTGTGGCAAGGGGCTGAGAGAAGAGTTTAACCGCCAGTGCTGGCTTGTCAAT GCCCTGGCCAAACTGGCCCAGCAGGTCCGGGAGGCAGCCCCATCTGCAAGGCAGGGAATC CTCCGCACGGGCCTGGAGGAGGTGAAGCAGTTCTTTGCCCTCAATGGCTCGTGCCGCTTG CCACTCAGCCCCAGTCTGCTGGTTAAGGGAATTGTGCCCAGGGACTGTTCCTACTTCAAC TCCAATGCTGTCCCCCTCAAACTCTCCTTCCAAAATGTGGATCCCCTGGGTGAGAACATC CGTGTCATCTTCAAGTGTGGGGACGACCTTCGCCAGGACATGCTAACGCTGCAGATGATT CGCATCATGAGCAAGATCTGGGTCCAGGAGGGGCTGGACATGCGCATGGTCATCTTCCGC TGCTTCTCCACCGGCCGGGGCAGAGGGATGGTGGAGATGATCCCTAATGCTGAGACCCTG CGTAAGATCCAGGTGGAGCATGGGGTGACCGGCTCGTTCAAGGACCGGCCCCTGGCAGAC TGGCTGCAGAAACACAACCCTGGGGAGGACGAGTATGAGAAGGCTGTGGAGAACTTTATC TACTCCTGCGCTGGCTGCTGCGTGGCCACGTACGTCTTGGGCATCTGTGACCGACATAAT GACAACATCATGCTGAAGACCACTGGTCACATGTTCCACATTGATTTTGGCCGCTTCCTG GGCCATGCCCAGATGTTTGGCAACATCAAGCGGGACCGTGCCCCCTTTGTCTTCACCTCG GACATGGCGTATGTCATCAACGGGGGTGACAAGCCTTCCAGCCGCTTCCATGATTTTGTT GACCTTTGCTGCCAAGCCTACAACCTCATTCGCAAGCACACCCACCTCTTCCTCAACCTT CTGGGCCTGATGTTGTCCTGTGGGATCCCTGAACTCTCAGACCTGGAGGACCTCAAGTAT GTGTACGATGCCCTGAGGCCTCAGGATACAGAGGCCAATGCCACTACCTACTTCACTAGG TTGATTGAGTCCAGCCTGGGCAGTGTAGCCACAAAGCTCAATTTTTTCATCCATAATCTG GCTCAGATGAAGTTCACGGGCTCAGATGACCGGCTGACCCTCTCCTTTGCCTCCCGAACA CACACTCTCAAGAGCTCTGGCCGAATCAGTGATGTTTTCCTCTGCCGCCATGAGAAGATC TTCCACCCCAACAAAGGCTATATATATGTGGTAAAGGTGATGCGAGAGAACACTCACGAG GCCACCTACATCCAGCGGACCTTTGAGGAGTTCCAGGAATTACACAATAAGTTGCGGCTG CTCTTCCCTTCTTCCCACTTGCCCAGCTTCCCTAGTCGCTTCGTGATCGGCCGCTCCCGG GGAGAGGCGGTGGCCGAGCGGCGGAGGGAGGAGCTAAACGGTTACATCTGGCACTTGATC CACGCACCCCCTGAGGTGGCCGAGTGTGATTTGGTGTACACCTTCTTCCACCCACTGCCC CGGGATGAGAAGGCTATGGGCACCAGCCCAGCTCCTAAGTCCTCAGATGGCACATGGGCC CGGCCCGTCGGAAAGGTGGGAGGGGAGGTGAAGCTGTCCATCTCCTACAAAAACAATAAA CTCTTCATCATGGTGATGCATATTCGGGGCTTGCAACTGCTCCAGGATGGAAATGACCCT GACCCCTATGTGAAAATTTACCTCCTTCCTGACCCTCAGAAAACCACTAAGAGGAAAACC AAAGTGGCCCGGAAAACCTGCAATCCTACCTACAATGAGATGTTGGTATATGATGGGATC CCCAAGGGTGACCTGCAGCAGCGGGAGCTCCAGCTGAGCGTGCTGAGTGAGCAGGGATTC TGGGAGAACGTCCTCCTCGGTGAGGTGAACATCCGCCTGCGAGAGCTGGACCTGGCTCAG GAGAAGACCGGCTGGTTCGCCCTGGGATCTCGAAGTCATGGCACCTTGTACGTAGTTTAA ACGAATTCGAGCTCGGTACCCGGGGATCCTCTAGAGTCGACCTGCAGGCATGCAAGCTGA TCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGAGTTGGCTGCTGCCACCGCTGAGCAATA ACTAGCATAACCCCTTGGGGCCTCTAAACGGGTCTTGAGGGGTTTTTTGCTGAAAGGAGG AACTATATCCGGTTCGCTTGCTGTCCATAAAACCGCCCAGTCTAGCTATCGCCATGTAAG CCCACTGCAAGCTACCTGCTTTCTCTTTGCGCTTGCGTTTTCCCTTGTCCAGATAGCCCA GTAGCTGACATTCATCCGGGGTCAGCACCGTTTCTGCGGACTGGCTTTCTACGTGTTCCG CTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTTGCGGCAGCGTGAGCTTCAAAAGAATTG CCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAGCCCTGCAAAGTAAACTGGATGGCTTTC TTGCCGCCAAGGATCTGATGGCGCAGGGGATCAAGATCTGATCAAGAGACAGGATGACGG TCGTTTCGCATGCTTGAACAAGATGGATTGCACGCAGGTTCTCCGGCCGCTTGGGTGGAG AGGCTATTCGGCTATGACTGGGCACAACAGACAATCGGCTGCTCTGATGCCGCCGTGTTC CGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTTGTCAAGACCGACCTGTCCGGTGCCCTG AATGAACTGCAGGACGAGGCAGCGCGGCTATCGTGGCTGGCCACGACGGGCGTTCCTTGC GCAGCTGTGCTCGACGTTGTCACTGAAGCGGGAAGGGACTGGCTGCTATTGGGCGAAGTG CCGGGGCAGGATCTCCTGTCATCTCACCTTGCTCCTGCCGAGAAAGTATCCATCATGGCT GATGCAATGCGGCGGCTGCATACGCTTGATCCGGCTACCTGCCCATTCGACCACCAAGCG AAACATCGCATCGAGCGAGCACGCACTCGGATGGAAGCCGGTCTTGTCGATCAGGATGAT CTGGACGAAGAGCATCAGGGGCTCGCGCCAGCCGAACTGTTCGCCAGGCTCAAGGCGCGT ATGCCGGATGGTGAGGATCTCGTCGTGACTCATGGCGATGCCTGCTTGCCGAATATCATG GTGGAAAATGGCCGCTTTTCTGGATTCATCGACTGTGGCCGGCTGGGTGTGGCGGACCGC TATCAGGACATAGCGTTGGCTACCCGTGATATTGCTGAAGAGCTTGGCGGCGAATGGGCT GACCGCTTCCTCGTGCTTTACGGTATCGCCGCTCCCGATTCGCAGCGCATCGCCTTCTAT CGCCTTCTTGACGAGTTCTTCTGAGCGGGACTCTGGGGTTCGAAATGACCGACCAAGCGA CGCCCAACCGGTATCAGCTCACTCAAAGGCGGTAATACGGTTATCCACAGAATCAGGGGA TAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGC CGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACG CTCAAGTCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGG AAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTT TCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGT GTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTG CGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACT GGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTT CTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGGACAGTATTTGGTATCTGCGCTCT GCTGAAGCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCAC CGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGATT TCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACG TTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTATAGTC CGGAAATACAGGAACGCACGCTGGATGGCCCTTCGCTGGGATGGTGAAACCATGAAAAAT GGCAGCTTCAGTGGATTAAGTGGGGGTAATGTGGCCTGTACCCTCTGGTTGCATAGGTAT TCATACGGTTAAAATTTATCAGGCGCGATTGCGGCAGTTTTTCGGGTGGTTTGTTGCCAT TTTTACCTGTCTGCTGCCGTGATCGCGCTGAACGCGTTTTAGCGGTGCGTACAATTAAGG GATTATGGTAAATCCACTTACTGTCTGCCCTCGTAGCCATCGAGATAAACCGCAGTACTC CGGCCACGATGCGTCCGGCGTAGAGGATCGAGATCTTTTCAGCCTGATACAGATTAAATC AGAACGCAGAAGCGGTCTGATAAAACAGAATTTGCCTGGCGGCAGTAGCGCGGTGGTCCC ACCTGACCCCATGCCGAACTCAGAAGTGAAACGCCGTAGCGCCGATGGTAGTGTGGGGTC TCCCCATGCGAGAGTAGGGAACTGCCAGGCATCAAATAAAACGAAAGGCTCAGTCGAAAG ACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGGTGAACGCTCTCCTGAGTAGGACAAATC CGCCGGGAGCGGATTTGAACGTTGCGAAGCAACGGCCCGGAGGGTGGCGGGCAGGACGCC CGCCATAAACTGCCAGGCATCAAATTAAGCAGAAGGCCATCCTGACGGATGGCCTTTTTG CGTTTCTACAAACTCTTTTGTTTATTTTTCTAAATACATTCAAATATGTATCCGCTCAT
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