ROUGE

Gene/Protein Characteristic Table for mFLJ00002

Link to : NEDO \| SWISS-PROT/TrEMBL
Features : DNA sequence \| Protein sequence

Accession No. :	AK131108
Description :	ATP-binding cassette, sub-family C, member 10 isoform mrp7A. multidrug resistance-associated protein 7.
Clone Name :	mbg13511 [Vector Info]
Source :	Mouse brain

Features of the cloned DNA sequence	Description

Length: 5652 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 1886 bp

Genome contig ID gi65550231r_43712913
PolyA signal sequence
(GATAAA,-19)
+----*----+----*----+----*----+----
TTTCATAATTTTATTTGATAAAATTCCTATCTTAC
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
ATTCTGTGTTTTAAAAAAATACTATTTCTGGTGTGAGGCAGAAATCCCCT

Genomic structure deduced by Blast search against draft genome sequences
Comparison with the corresponding KIAA cDNA.

KIAA Alignment based on:

FLJ00002 DNA sequence, AA sequence, Physical map

KIAA	Alignment based on:
FLJ00002	DNA sequence, AA sequence, Physical map

Features of the protein sequence	Description

Coding region: 2..1384, 1498..2241, 2297..3733, 4497..5393
Length: 1486 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
BAD21358	100.0	mFLJ00002 prote...	Mus musculus
EDM18817	90.7	ATP-binding cas...	Rattus norvegicus
XP_518494	82.7	ATP-binding cas...	Pan troglodytes
Q5T3U5	82.5	Multidrug resis...	Homo sapiens
BAA92227	82.5	FLJ00002 protei...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other ROUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	ROUGE_ID
AB093298	7.5e-19	25.9	mKIAA1520
AK173034	7.7e-08	28.0	mKIAA0822
AK129463	3.5e-07	24.0	mKIAA1888

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR001140 285 551 PF00664 ABC transporter

IPR003439 626 800 PF00005 ABC transporter related

IPR001140 934 1202 PF00664 ABC transporter

IPR003439 1267 1449 PF00005 ABC transporter related

HMMSmart IPR003593 625 808 SM00382 AAA ATPase

IPR003593 1266 1450 SM00382 AAA ATPase

ProfileScan IPR001687 628 650 PS50101 ATP/GTP-binding site motif A (P-loop)

IPR003439 726 797 PS50100 ABC transporter related

IPR001687 1269 1294 PS50101 ATP/GTP-binding site motif A (P-loop)

IPR003439 1376 1446 PS50100 ABC transporter related

ScanRegExp IPR003439 726 740 PS00211 ABC transporter related

IPR003439 1376 1390 PS00211 ABC transporter related

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR001140	285	551	PF00664	ABC transporter
IPR003439	626	800	PF00005	ABC transporter related
IPR001140	934	1202	PF00664	ABC transporter
IPR003439	1267	1449	PF00005	ABC transporter related
HMMSmart	IPR003593	625	808	SM00382	AAA ATPase
IPR003593	1266	1450	SM00382	AAA ATPase
ProfileScan	IPR001687	628	650	PS50101	ATP/GTP-binding site motif A (P-loop)
IPR003439	726	797	PS50100	ABC transporter related
IPR001687	1269	1294	PS50101	ATP/GTP-binding site motif A (P-loop)
IPR003439	1376	1446	PS50100	ABC transporter related
ScanRegExp	IPR003439	726	740	PS00211	ABC transporter related
IPR003439	1376	1390	PS00211	ABC transporter related

Prediction of transmembrane (TM) segments

Method From To amino acid sequence

SOSUI 27 49 CFTQLVLSALPHALLAVLSACHL

69 91 LAASFLLSIFPLLDLLPVVLPPG

99 121 LEVLAGCVTAVAWFTHSLALWAL

134 156 ALALAAFLPTPALVLTLLWHCQR

169 191 GRVCLLILQLAAVLAYGLGWAAP

286 308 LALGLLKMVGTMLGFSGPLLLSL

320 342 LSHGLLYVLGLAGGTVISAVLQN

416 438 YQQVGMAFLAGLVLALLLVPVNK

504 526 AACVYLWAALPVVICITIFITYV

537 559 VFTALALVRMLILPLNNFPWVIN

879 901 RAMGSGLAAAILVSLLLMQATRN

970 992 FYLIVYATIAGVNSLCTLLRAVL

1054 1076 SVGLLGLLAVLGSGLPWLLLLLP

1161 1183 LMGAAVVSAIAGIALVQHQQGLA

Method	From	To	amino acid sequence
SOSUI	27	49	CFTQLVLSALPHALLAVLSACHL
69	91	LAASFLLSIFPLLDLLPVVLPPG
99	121	LEVLAGCVTAVAWFTHSLALWAL
134	156	ALALAAFLPTPALVLTLLWHCQR
169	191	GRVCLLILQLAAVLAYGLGWAAP
286	308	LALGLLKMVGTMLGFSGPLLLSL
320	342	LSHGLLYVLGLAGGTVISAVLQN
416	438	YQQVGMAFLAGLVLALLLVPVNK
504	526	AACVYLWAALPVVICITIFITYV
537	559	VFTALALVRMLILPLNNFPWVIN
879	901	RAMGSGLAAAILVSLLLMQATRN
970	992	FYLIVYATIAGVNSLCTLLRAVL
1054	1076	SVGLLGLLAVLGSGLPWLLLLLP
1161	1183	LMGAAVVSAIAGIALVQHQQGLA

How to obtain mKIAA clone(s) Back to the ROUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	YES

Length of 3'UTR	1886 bp
Genome contig ID	gi65550231r_43712913
PolyA signal sequence (GATAAA,-19)	+--------+--------+----*----+---- TTTCATAATTTTATTTGATAAAATTCCTATCTTAC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* ATTCTGTGTTTTAAAAAAATACTATTTCTGGTGTGAGGCAGAAATCCCCT

Gene/Protein Characteristic Table for mFLJ00002

Features of the cloned DNA sequence

Features of the protein sequence