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SpecieshumanProduct IDFXC01373Cloning SiteSgfI-PmeIGeneKIBB4176SymbolGABRA2
Alias : DEE78, EIEE78Descriptiongamma-aminobutyric acid (GABA) A receptor, alpha 2, transcript variant 1Original Clone IDfk07282
Length: 1353 bp
Restriction map A
Restriction map B
Genomic Structure
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Length: 451 aa
Result of homology search against CCDS protein database (
FASTA output,
Multiple alignment)
Entry Exp ID% symbol CCDS3471.1 9.4e-196 100.0 GABRA2 CCDS82921.1 2.5e-153 87.6 GABRA2 CCDS4357.1 6.5e-147 81.3 GABRA1 CCDS45194.1 3.5e-140 76.5 GABRA5 CCDS14706.1 1e-123 75.1 GABRA3
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)
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Result of InterProScan
Search method interpro_ID From To Entry Definition FPrintScan IPR005432 9 27 PR01615 Gamma-aminobutyric-acid A receptor IPR001390 40 51 PR01079 Gamma-aminobutyric-acid A receptor IPR001390 60 77 PR01079 Gamma-aminobutyric-acid A receptor IPR006201 88 104 PR00252 Neurotransmitter-gated ion-channel IPR001390 104 116 PR01079 Gamma-aminobutyric-acid A receptor IPR006201 120 131 PR00252 Neurotransmitter-gated ion-channel IPR006201 166 180 PR00252 Neurotransmitter-gated ion-channel IPR001390 196 208 PR01079 Gamma-aminobutyric-acid A receptor IPR001390 213 235 PR01079 Gamma-aminobutyric-acid A receptor IPR006201 244 256 PR00252 Neurotransmitter-gated ion-channel IPR006028 253 273 PR00253 Gamma-aminobutyric acid A receptor IPR006028 279 300 PR00253 Gamma-aminobutyric acid A receptor IPR001390 306 319 PR01079 Gamma-aminobutyric-acid A receptor IPR006028 313 334 PR00253 Gamma-aminobutyric acid A receptor IPR005432 347 362 PR01615 Gamma-aminobutyric-acid A receptor IPR005432 366 380 PR01615 Gamma-aminobutyric-acid A receptor IPR005432 384 408 PR01615 Gamma-aminobutyric-acid A receptor IPR001390 410 422 PR01079 Gamma-aminobutyric-acid A receptor IPR006028 420 440 PR00253 Gamma-aminobutyric acid A receptor IPR001390 435 446 PR01079 Gamma-aminobutyric-acid A receptor HMMPfam IPR006202 43 250 PF02931 Neurotransmitter-gated ion-channel ligand-binding IPR006029 257 340 PF02932 Neurotransmitter-gated ion-channel transmembrane domain IPR006029 358 437 PF02932 Neurotransmitter-gated ion-channel transmembrane domain HMMTigr IPR006201 23 440 TIGR00860 Neurotransmitter-gated ion-channel
Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length SOSUI2 1 8 YNMQFLLFVFLVWDPARLVLANI 30 SECONDARY 23 2 253 FVIQTYLPCIMTVILSQVSFWL 274 PRIMARY 22 3 314 DWFIAVCYAFVFSALIEFATVNY 336 PRIMARY 23
Result of homology search against disease genes in OMIM database(FASTA output,
Multiple alignment)
H_id H_len (aa) OMIM_No. ID (%) Q_ali/Q_len (%) XP_016863472 451 103780,137140 100.0 100.0 NP_000798 451 103780,137140 100.0 100.0 NP_001107647 451 103780,137140 100.0 100.0 XP_016863471 451 103780,137140 100.0 100.0 XP_005248137 396 103780,137140 93.9 87.8 Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.comCloned ORF Nucleotide sequence for pF1KB4176 Download>KIBB4176 1353 bp ATGAAGACAAAATTGAACATCTACAACATGCAGTTCCTGCTTTTTGTTTTCTTGGTGTGG GACCCTGCCAGGTTGGTGCTGGCTAACATCCAAGAAGATGAGGCTAAAAATAACATTACC ATCTTTACGAGAATTCTTGACAGACTTCTGGATGGTTACGATAATCGGCTTAGACCAGGA CTGGGAGACAGTATTACTGAAGTCTTCACTAACATCTACGTGACCAGTTTTGGCCCTGTC TCAGATACAGATATGGAATATACAATTGATGTTTTCTTTCGACAAAAATGGAAAGATGAA CGTTTAAAATTTAAAGGTCCTATGAATATCCTTCGACTAAACAATTTAATGGCTAGCAAA ATCTGGACTCCAGATACCTTTTTTCACAATGGGAAAAAATCAGTAGCTCATAATATGACA ATGCCAAATAAGTTGCTTCGAATTCAGGATGATGGGACTCTGCTGTATACCATGAGGCTT ACAGTTCAAGCTGAATGCCCAATGCACTTGGAGGATTTCCCAATGGATGCTCATTCATGT CCTCTGAAATTTGGCAGCTATGCATATACAACTTCAGAGGTCACTTATATTTGGACTTAC AATGCATCTGATTCAGTACAGGTTGCTCCTGATGGCTCTAGGTTAAATCAATATGACCTG CTGGGCCAATCAATCGGAAAGGAGACAATTAAATCCAGTACAGGTGAATATACTGTAATG ACAGCTCATTTCCACCTGAAAAGAAAAATTGGGTATTTTGTGATTCAAACCTATCTGCCT TGCATCATGACTGTCATTCTCTCCCAAGTTTCATTCTGGCTTAACAGAGAATCTGTGCCT GCAAGAACTGTGTTTGGAGTAACAACTGTCCTAACAATGACAACTCTAAGCATCAGTGCT CGGAATTCTCTCCCCAAAGTGGCTTATGCAACTGCCATGGACTGGTTTATTGCTGTTTGT TATGCATTTGTGTTCTCTGCCCTAATTGAATTTGCAACTGTTAATTACTTCACCAAAAGA GGATGGGCTTGGGATGGGAAGAGTGTAGTAAATGACAAGAAAAAAGAAAAGGCTTCCGTT ATGATACAGAACAACGCTTATGCAGTGGCTGTTGCCAATTATGCCCCGAATCTTTCAAAA GATCCAGTTCTCTCCACCATCTCCAAGAGTGCAACCACGCCAGAACCCAACAAGAAGCCA GAAAACAAGCCAGCTGAAGCAAAGAAAACTTTCAACAGTGTTAGCAAAATTGACAGAATG TCCAGAATAGTTTTTCCAGTTTTGTTTGGTACCTTTAATTTAGTTTACTGGGCTACATAT TTAAACAGAGAACCTGTATTAGGGGTCAGTCCT
Cloned ORF protein sequence for pF1KB4176 Download>KIBB4176 451 aa MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
Nucleotide Sequence (with vector) for pF1KB4176 Download>pF1KB4176 4466 bp GGATCTCGATCCCGCGAAATTAATACGACTCACTATAGGGGAATTGTGAGCGGATAACAA TTCCCCACTAGTAATAATTTTCTTTAACTTTAGTAAGGAGCGATCGCCATGAAGACAAAA TTGAACATCTACAACATGCAGTTCCTGCTTTTTGTTTTCTTGGTGTGGGACCCTGCCAGG TTGGTGCTGGCTAACATCCAAGAAGATGAGGCTAAAAATAACATTACCATCTTTACGAGA ATTCTTGACAGACTTCTGGATGGTTACGATAATCGGCTTAGACCAGGACTGGGAGACAGT ATTACTGAAGTCTTCACTAACATCTACGTGACCAGTTTTGGCCCTGTCTCAGATACAGAT ATGGAATATACAATTGATGTTTTCTTTCGACAAAAATGGAAAGATGAACGTTTAAAATTT AAAGGTCCTATGAATATCCTTCGACTAAACAATTTAATGGCTAGCAAAATCTGGACTCCA GATACCTTTTTTCACAATGGGAAAAAATCAGTAGCTCATAATATGACAATGCCAAATAAG TTGCTTCGAATTCAGGATGATGGGACTCTGCTGTATACCATGAGGCTTACAGTTCAAGCT GAATGCCCAATGCACTTGGAGGATTTCCCAATGGATGCTCATTCATGTCCTCTGAAATTT GGCAGCTATGCATATACAACTTCAGAGGTCACTTATATTTGGACTTACAATGCATCTGAT TCAGTACAGGTTGCTCCTGATGGCTCTAGGTTAAATCAATATGACCTGCTGGGCCAATCA ATCGGAAAGGAGACAATTAAATCCAGTACAGGTGAATATACTGTAATGACAGCTCATTTC CACCTGAAAAGAAAAATTGGGTATTTTGTGATTCAAACCTATCTGCCTTGCATCATGACT GTCATTCTCTCCCAAGTTTCATTCTGGCTTAACAGAGAATCTGTGCCTGCAAGAACTGTG TTTGGAGTAACAACTGTCCTAACAATGACAACTCTAAGCATCAGTGCTCGGAATTCTCTC CCCAAAGTGGCTTATGCAACTGCCATGGACTGGTTTATTGCTGTTTGTTATGCATTTGTG TTCTCTGCCCTAATTGAATTTGCAACTGTTAATTACTTCACCAAAAGAGGATGGGCTTGG GATGGGAAGAGTGTAGTAAATGACAAGAAAAAAGAAAAGGCTTCCGTTATGATACAGAAC AACGCTTATGCAGTGGCTGTTGCCAATTATGCCCCGAATCTTTCAAAAGATCCAGTTCTC TCCACCATCTCCAAGAGTGCAACCACGCCAGAACCCAACAAGAAGCCAGAAAACAAGCCA GCTGAAGCAAAGAAAACTTTCAACAGTGTTAGCAAAATTGACAGAATGTCCAGAATAGTT TTTCCAGTTTTGTTTGGTACCTTTAATTTAGTTTACTGGGCTACATATTTAAACAGAGAA CCTGTATTAGGGGTCAGTCCTGTTTAAACGAATTCGAGCTCGGTACCCGGGGATCCTCTA GAGTCGACCTGCAGGCATGCAAGCTGATCCGGCTGCTAACAAAGCCCGAAAGGAAGCTGA GTTGGCTGCTGCCACCGCTGAGCAATAACTAGCATAACCCCTTGGGGCCTCTAAACGGGT CTTGAGGGGTTTTTTGCTGAAAGGAGGAACTATATCCGGTTCGCTTGCTGTCCATAAAAC CGCCCAGTCTAGCTATCGCCATGTAAGCCCACTGCAAGCTACCTGCTTTCTCTTTGCGCT TGCGTTTTCCCTTGTCCAGATAGCCCAGTAGCTGACATTCATCCGGGGTCAGCACCGTTT CTGCGGACTGGCTTTCTACGTGTTCCGCTTCCTTTAGCAGCCCTTGCGCCCTGAGTGCTT GCGGCAGCGTGAGCTTCAAAAGAATTGCCAGCTGGGGCGCCCTCTGGTAAGGTTGGGAAG CCCTGCAAAGTAAACTGGATGGCTTTCTTGCCGCCAAGGATCTGATGGCGCAGGGGATCA AGATCTGATCAAGAGACAGGATGACGGTCGTTTCGCATGCTTGAACAAGATGGATTGCAC GCAGGTTCTCCGGCCGCTTGGGTGGAGAGGCTATTCGGCTATGACTGGGCACAACAGACA ATCGGCTGCTCTGATGCCGCCGTGTTCCGGCTGTCAGCGCAGGGGCGCCCGGTTCTTTTT GTCAAGACCGACCTGTCCGGTGCCCTGAATGAACTGCAGGACGAGGCAGCGCGGCTATCG TGGCTGGCCACGACGGGCGTTCCTTGCGCAGCTGTGCTCGACGTTGTCACTGAAGCGGGA AGGGACTGGCTGCTATTGGGCGAAGTGCCGGGGCAGGATCTCCTGTCATCTCACCTTGCT CCTGCCGAGAAAGTATCCATCATGGCTGATGCAATGCGGCGGCTGCATACGCTTGATCCG GCTACCTGCCCATTCGACCACCAAGCGAAACATCGCATCGAGCGAGCACGCACTCGGATG GAAGCCGGTCTTGTCGATCAGGATGATCTGGACGAAGAGCATCAGGGGCTCGCGCCAGCC GAACTGTTCGCCAGGCTCAAGGCGCGTATGCCGGATGGTGAGGATCTCGTCGTGACTCAT GGCGATGCCTGCTTGCCGAATATCATGGTGGAAAATGGCCGCTTTTCTGGATTCATCGAC TGTGGCCGGCTGGGTGTGGCGGACCGCTATCAGGACATAGCGTTGGCTACCCGTGATATT GCTGAAGAGCTTGGCGGCGAATGGGCTGACCGCTTCCTCGTGCTTTACGGTATCGCCGCT CCCGATTCGCAGCGCATCGCCTTCTATCGCCTTCTTGACGAGTTCTTCTGAGCGGGACTC TGGGGTTCGAAATGACCGACCAAGCGACGCCCAACCGGACTATAAAAGGATCTAGGTGAA GATCCTTTTTGATAATCTCATGACCAAAATCCCTTAACGTGAGTTTTCGTTCCACTGAGC GTCAGACCCCGTAGAAAAGATCAAAGGATCTTCTTGAAATCCTTTTTTTCTGCGCGTAAT CTGCTGCTTGCAAACAAAAAAACCACCGCTACCAGCGGTGGTTTGTTTGCCGGATCAAGA GCTACCAACTCTTTTTCCGAAGGTAACTGGCTTCAGCAGAGCGCAGATACCAAATACTGT CCTTCTAGTGTAGCCGTAGTTAGGCCACCACTTCAAGAACTCTGTAGCACCGCCTACATA CCTCGCTCTGCTAATCCTGTTACCAGTGGCTGCTGCCAGTGGCGATAAGTCGTGTCTTAC CGGGTTGGACTCAAGACGATAGTTACCGGATAAGGCGCAGCGGTCGGGCTGAACGGGGGG TTCGTGCACACAGCCCAGCTTGGAGCGAACGACCTACACCGAACTGAGATACCTACAGCG TGAGCTATGAGAAAGCGCCACGCTTCCCGAAGGGAGAAAGGCGGACAGGTATCCGGTAAG CGGCAGGGTCGGAACAGGAGAGCGCACGAGGGAGCTTCCAGGGGGAAACGCCTGGTATCT TTATAGTCCTGTCGGGTTTCGCCACCTCTGACTTGAGCGTCGATTTTTGTGATGCTCGTC AGGGGGGCGGAGCCTATGGAAAAACGCCAGCAACGCGGCCTTTTTACGGTTCCTGGCCTT TTGCTGGCCTTTTGCTCACATGTTCTTTCCTGCGTTATCCCCTGATTCTGTGGATAACCG TATTACCGCCTTTGAGTGAGCTGATACCGGAAATACAGGAACGCACGCTGGATGGCCCTT CGCTGGGATGGTGAAACCATGAAAAATGGCAGCTTCAGTGGATTAAGTGGGGGTAATGTG GCCTGTACCCTCTGGTTGCATAGGTATTCATACGGTTAAAATTTATCAGGCGCGATTGCG GCAGTTTTTCGGGTGGTTTGTTGCCATTTTTACCTGTCTGCTGCCGTGATCGCGCTGAAC GCGTTTTAGCGGTGCGTACAATTAAGGGATTATGGTAAATCCACTTACTGTCTGCCCTCG TAGCCATCGAGATAAACCGCAGTACTCCGGCCACGATGCGTCCGGCGTAGAGGATCGAGA TCTTTTCAGCCTGATACAGATTAAATCAGAACGCAGAAGCGGTCTGATAAAACAGAATTT GCCTGGCGGCAGTAGCGCGGTGGTCCCACCTGACCCCATGCCGAACTCAGAAGTGAAACG CCGTAGCGCCGATGGTAGTGTGGGGTCTCCCCATGCGAGAGTAGGGAACTGCCAGGCATC AAATAAAACGAAAGGCTCAGTCGAAAGACTGGGCCTTTCGTTTTATCTGTTGTTTGTCGG TGAACGCTCTCCTGAGTAGGACAAATCCGCCGGGAGCGGATTTGAACGTTGCGAAGCAAC GGCCCGGAGGGTGGCGGGCAGGACGCCCGCCATAAACTGCCAGGCATCAAATTAAGCAGA AGGCCATCCTGACGGATGGCCTTTTTGCGTTTCTACAAACTCTTTTGTTTATTTTTCTAA ATACATTCAAATATGTATCCGCTCAT
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