Result of FASTA (omim) for pF1KE2582
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2582, 956 aa
  1>>>pF1KE2582     956 - 956 aa - 956 aa
Library: /omim/omim.rfq.tfa
  65951994 residues in 93482 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.7056+/-0.000409; mu= -12.6949+/- 0.025
 mean_var=385.4133+/-79.635, 0's: 0 Z-trim(122.5): 29  B-trim: 2475 in 2/55
 Lambda= 0.065330
 statistics sampled from 42602 (42637) to 42602 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.456), width:  16
 Scan time:  7.750

The best scores are:                                      opt bits E(93482)
NP_570899 (OMIM: 614657) angiomotin-like protein 1 ( 956) 6310 609.5 2.9e-173
XP_005273855 (OMIM: 614657) angiomotin-like protei ( 985) 6195 598.6 5.5e-170
XP_011540928 (OMIM: 614657) angiomotin-like protei ( 935) 5879 568.8 4.8e-161
NP_001287936 (OMIM: 614657) angiomotin-like protei ( 906) 5870 568.0 8.5e-161
XP_005273858 (OMIM: 614657) angiomotin-like protei ( 870) 5729 554.7 8.2e-157
XP_006718835 (OMIM: 614657) angiomotin-like protei ( 677) 4199 410.4 1.7e-113
XP_011540930 (OMIM: 614657) angiomotin-like protei ( 604) 3783 371.2 9.9e-102
XP_005262144 (OMIM: 300410) angiomotin isoform X1  (1084) 1884 192.3 1.2e-47
NP_001106962 (OMIM: 300410) angiomotin isoform 1 [ (1084) 1884 192.3 1.2e-47
XP_011529177 (OMIM: 300410) angiomotin isoform X1  (1084) 1884 192.3 1.2e-47
XP_005262147 (OMIM: 300410) angiomotin isoform X2  ( 675) 1847 188.7 9.2e-47
XP_016884778 (OMIM: 300410) angiomotin isoform X2  ( 675) 1847 188.7 9.2e-47
NP_573572 (OMIM: 300410) angiomotin isoform 2 [Hom ( 675) 1847 188.7 9.2e-47
NP_001350872 (OMIM: 614658) angiomotin-like protei ( 779) 1306 137.8 2.3e-31
XP_006713717 (OMIM: 614658) angiomotin-like protei ( 779) 1306 137.8 2.3e-31
XP_016862069 (OMIM: 614658) angiomotin-like protei ( 780) 1306 137.8 2.3e-31
XP_016862070 (OMIM: 614658) angiomotin-like protei ( 780) 1306 137.8 2.3e-31
XP_016862071 (OMIM: 614658) angiomotin-like protei ( 780) 1306 137.8 2.3e-31
NP_057285 (OMIM: 614658) angiomotin-like protein 2 ( 780) 1306 137.8 2.3e-31
NP_001265612 (OMIM: 614658) angiomotin-like protei ( 837) 1306 137.8 2.5e-31
NP_001265614 (OMIM: 614658) angiomotin-like protei ( 777) 1303 137.5 2.8e-31


>>NP_570899 (OMIM: 614657) angiomotin-like protein 1 iso  (956 aa)
 initn: 6310 init1: 6310 opt: 6310  Z-score: 3232.3  bits: 609.5 E(93482): 2.9e-173
Smith-Waterman score: 6310; 100.0% identity (100.0% similar) in 956 aa overlap (1-956:1-956)

               10        20        30        40        50        60
pF1KE2 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
              850       860       870       880       890       900

              910       920       930       940       950      
pF1KE2 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
              910       920       930       940       950      

>>XP_005273855 (OMIM: 614657) angiomotin-like protein 1   (985 aa)
 initn: 6193 init1: 6193 opt: 6195  Z-score: 3173.6  bits: 598.6 E(93482): 5.5e-170
Smith-Waterman score: 6195; 99.7% identity (99.7% similar) in 944 aa overlap (13-956:42-985)

                                 10        20        30        40  
pF1KE2                   MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDF
                                     :   ::::::::::::::::::::::::::
XP_005 GAWLSHAGIHHFASTRADSEFVEASPASYSPDELGSPSACYSPSSPVQVLEDSTYFSPDF
              20        30        40        50        60        70 

             50        60        70        80        90       100  
pF1KE2 QLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRL
              80        90       100       110       120       130 

            110       120       130       140       150       160  
pF1KE2 IQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQG
             140       150       160       170       180       190 

            170       180       190       200       210       220  
pF1KE2 QEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAG
             200       210       220       230       240       250 

            230       240       250       260       270       280  
pF1KE2 GTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGS
             260       270       280       290       300       310 

            290       300       310       320       330       340  
pF1KE2 GNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGML
             320       330       340       350       360       370 

            350       360       370       380       390       400  
pF1KE2 HEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPL
             380       390       400       410       420       430 

            410       420       430       440       450       460  
pF1KE2 HSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGY
             440       450       460       470       480       490 

            470       480       490       500       510       520  
pF1KE2 YDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL
             500       510       520       530       540       550 

            530       540       550       560       570       580  
pF1KE2 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD
             560       570       580       590       600       610 

            590       600       610       620       630       640  
pF1KE2 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD
             620       630       640       650       660       670 

            650       660       670       680       690       700  
pF1KE2 ALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAM
             680       690       700       710       720       730 

            710       720       730       740       750       760  
pF1KE2 NAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKI
             740       750       760       770       780       790 

            770       780       790       800       810       820  
pF1KE2 IEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEE
             800       810       820       830       840       850 

            830       840       850       860       870       880  
pF1KE2 KTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKS
             860       870       880       890       900       910 

            890       900       910       920       930       940  
pF1KE2 AELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLH
             920       930       940       950       960       970 

            950      
pF1KE2 KPEFPDGEMMEVLI
       ::::::::::::::
XP_005 KPEFPDGEMMEVLI
             980     

>>XP_011540928 (OMIM: 614657) angiomotin-like protein 1   (935 aa)
 initn: 5874 init1: 5874 opt: 5879  Z-score: 3012.9  bits: 568.8 E(93482): 4.8e-161
Smith-Waterman score: 5879; 96.7% identity (98.3% similar) in 927 aa overlap (32-956:9-935)

              10        20        30        40          50         
pF1KE2 WRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPD--FQLYSGRHETSALTVEAT
                                     ::.....:     .. : : ..  . .  .
XP_011                       MDLSEKWTLEEGAWLSHAGIHHFASTRADSEFVEASPA
                                     10        20        30        

      60        70        80        90       100       110         
pF1KE2 SSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLL
       :   ...:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYSPDELVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLL
       40        50        60        70        80        90        

     120       130       140       150       160       170         
pF1KE2 AIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRST
      100       110       120       130       140       150        

     180       190       200       210       220       230         
pF1KE2 QPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRA
      160       170       180       190       200       210        

     240       250       260       270       280       290         
pF1KE2 NSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQP
      220       230       240       250       260       270        

     300       310       320       330       340       350         
pF1KE2 AGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDV
      280       290       300       310       320       330        

     360       370       380       390       400       410         
pF1KE2 AVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQ
      340       350       360       370       380       390        

     420       430       440       450       460       470         
pF1KE2 PPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRI
      400       410       420       430       440       450        

     480       490       500       510       520       530         
pF1KE2 SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED
      460       470       480       490       500       510        

     540       550       560       570       580       590         
pF1KE2 KAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEEL
      520       530       540       550       560       570        

     600       610       620       630       640       650         
pF1KE2 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMP
      580       590       600       610       620       630        

     660       670       680       690       700       710         
pF1KE2 EYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINH
      640       650       660       670       680       690        

     720       730       740       750       760       770         
pF1KE2 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKD
      700       710       720       730       740       750        

     780       790       800       810       820       830         
pF1KE2 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHE
      760       770       780       790       800       810        

     840       850       860       870       880       890         
pF1KE2 HASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRL
      820       830       840       850       860       870        

     900       910       920       930       940       950      
pF1KE2 STTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
      880       890       900       910       920       930     

>>NP_001287936 (OMIM: 614657) angiomotin-like protein 1   (906 aa)
 initn: 5870 init1: 5870 opt: 5870  Z-score: 3008.5  bits: 568.0 E(93482): 8.5e-161
Smith-Waterman score: 5877; 94.8% identity (94.8% similar) in 956 aa overlap (1-956:1-906)

               10        20        30        40        50        60
pF1KE2 MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATS
       ::::::::::::::::                                            
NP_001 MWRAKLRRGTCEPAVK--------------------------------------------
               10                                                  

               70        80        90       100       110       120
pF1KE2 SIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------VEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLA
               20        30        40        50        60        70

              130       140       150       160       170       180
pF1KE2 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQ
               80        90       100       110       120       130

              190       200       210       220       230       240
pF1KE2 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRAN
              140       150       160       170       180       190

              250       260       270       280       290       300
pF1KE2 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPA
              200       210       220       230       240       250

              310       320       330       340       350       360
pF1KE2 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVA
              260       270       280       290       300       310

              370       380       390       400       410       420
pF1KE2 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQP
              320       330       340       350       360       370

              430       440       450       460       470       480
pF1KE2 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRIS
              380       390       400       410       420       430

              490       500       510       520       530       540
pF1KE2 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDK
              440       450       460       470       480       490

              550       560       570       580       590       600
pF1KE2 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELR
              500       510       520       530       540       550

              610       620       630       640       650       660
pF1KE2 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPE
              560       570       580       590       600       610

              670       680       690       700       710       720
pF1KE2 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHS
              620       630       640       650       660       670

              730       740       750       760       770       780
pF1KE2 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDA
              680       690       700       710       720       730

              790       800       810       820       830       840
pF1KE2 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEH
              740       750       760       770       780       790

              850       860       870       880       890       900
pF1KE2 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS
              800       810       820       830       840       850

              910       920       930       940       950      
pF1KE2 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
              860       870       880       890       900      

>>XP_005273858 (OMIM: 614657) angiomotin-like protein 1   (870 aa)
 initn: 5729 init1: 5729 opt: 5729  Z-score: 2937.0  bits: 554.7 E(93482): 8.2e-157
Smith-Waterman score: 5729; 100.0% identity (100.0% similar) in 870 aa overlap (87-956:1-870)

         60        70        80        90       100       110      
pF1KE2 EATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENM
                                     ::::::::::::::::::::::::::::::
XP_005                               MRGSEDAAAGTVLQRLIQEQLRYGTPTENM
                                             10        20        30

        120       130       140       150       160       170      
pF1KE2 NLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQV
               40        50        60        70        80        90

        180       190       200       210       220       230      
pF1KE2 RSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTV
              100       110       120       130       140       150

        240       250       260       270       280       290      
pF1KE2 NRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSP
              160       170       180       190       200       210

        300       310       320       330       340       350      
pF1KE2 AQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVR
              220       230       240       250       260       270

        360       370       380       390       400       410      
pF1KE2 TDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALG
              280       290       300       310       320       330

        420       430       440       450       460       470      
pF1KE2 APQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKEL
              340       350       360       370       380       390

        480       490       500       510       520       530      
pF1KE2 QRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEG
              400       410       420       430       440       450

        540       550       560       570       580       590      
pF1KE2 HEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLE
              460       470       480       490       500       510

        600       610       620       630       640       650      
pF1KE2 EELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPA
              520       530       540       550       560       570

        660       670       680       690       700       710      
pF1KE2 NMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTI
              580       590       600       610       620       630

        720       730       740       750       760       770      
pF1KE2 INHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRS
              640       650       660       670       680       690

        780       790       800       810       820       830      
pF1KE2 RKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKE
              700       710       720       730       740       750

        840       850       860       870       880       890      
pF1KE2 HHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSR
              760       770       780       790       800       810

        900       910       920       930       940       950      
pF1KE2 GRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
              820       830       840       850       860       870

>>XP_006718835 (OMIM: 614657) angiomotin-like protein 1   (677 aa)
 initn: 4197 init1: 4197 opt: 4199  Z-score: 2159.3  bits: 410.4 E(93482): 1.7e-113
Smith-Waterman score: 4199; 99.5% identity (99.5% similar) in 636 aa overlap (13-648:42-677)

                                 10        20        30        40  
pF1KE2                   MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDF
                                     :   ::::::::::::::::::::::::::
XP_006 GAWLSHAGIHHFASTRADSEFVEASPASYSPDELGSPSACYSPSSPVQVLEDSTYFSPDF
              20        30        40        50        60        70 

             50        60        70        80        90       100  
pF1KE2 QLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRL
              80        90       100       110       120       130 

            110       120       130       140       150       160  
pF1KE2 IQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQG
             140       150       160       170       180       190 

            170       180       190       200       210       220  
pF1KE2 QEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAG
             200       210       220       230       240       250 

            230       240       250       260       270       280  
pF1KE2 GTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGS
             260       270       280       290       300       310 

            290       300       310       320       330       340  
pF1KE2 GNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGML
             320       330       340       350       360       370 

            350       360       370       380       390       400  
pF1KE2 HEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPL
             380       390       400       410       420       430 

            410       420       430       440       450       460  
pF1KE2 HSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGY
             440       450       460       470       480       490 

            470       480       490       500       510       520  
pF1KE2 YDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRL
             500       510       520       530       540       550 

            530       540       550       560       570       580  
pF1KE2 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILD
             560       570       580       590       600       610 

            590       600       610       620       630       640  
pF1KE2 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELD
             620       630       640       650       660       670 

            650       660       670       680       690       700  
pF1KE2 ALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAM
       ::::::                                                      
XP_006 ALRTQQ                                                      
                                                                   

>>XP_011540930 (OMIM: 614657) angiomotin-like protein 1   (604 aa)
 initn: 3775 init1: 3775 opt: 3783  Z-score: 1948.1  bits: 371.2 E(93482): 9.9e-102
Smith-Waterman score: 3783; 99.2% identity (99.3% similar) in 591 aa overlap (366-956:15-604)

         340       350       360       370       380       390     
pF1KE2 DQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQT
                                     : : : . ::::::::::::::::::::::
XP_011                 MHCILCTPQERQLLPWPLY-TPSRPCQLPFPSTMQQHSPMSSQT
                               10         20        30        40   

         400       410       420       430       440       450     
pF1KE2 SSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVL
            50        60        70        80        90       100   

         460       470       480       490       500       510     
pF1KE2 HQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFN
           110       120       130       140       150       160   

         520       530       540       550       560       570     
pF1KE2 RDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHR
           170       180       190       200       210       220   

         580       590       600       610       620       630     
pF1KE2 RHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRT
           230       240       250       260       270       280   

         640       650       660       670       680       690     
pF1KE2 WLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEES
           290       300       310       320       330       340   

         700       710       720       730       740       750     
pF1KE2 TIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTI
           350       360       370       380       390       400   

         760       770       780       790       800       810     
pF1KE2 KNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQL
           410       420       430       440       450       460   

         820       830       840       850       860       870     
pF1KE2 AEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDS
           470       480       490       500       510       520   

         880       890       900       910       920       930     
pF1KE2 STQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRG
           530       540       550       560       570       580   

         940       950      
pF1KE2 RVSSLLHKPEFPDGEMMEVLI
       :::::::::::::::::::::
XP_011 RVSSLLHKPEFPDGEMMEVLI
           590       600    

>>XP_005262144 (OMIM: 300410) angiomotin isoform X1 [Hom  (1084 aa)
 initn: 2374 init1: 862 opt: 1884  Z-score: 977.0  bits: 192.3 E(93482): 1.2e-47
Smith-Waterman score: 2643; 52.5% identity (72.6% similar) in 901 aa overlap (87-884:1-871)

         60        70        80        90         100       110    
pF1KE2 EATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAG--TVLQRLIQEQLRYGTPTE
                                     ::.::.  .:  ::::::.:::::::.:.:
XP_005                               MRNSEEQPSGGTTVLQRLLQEQLRYGNPSE
                                             10        20        30

          120       130          140         150       160         
pF1KE2 NMNLLAIQHQATGSAGPAHPT---NNFSSTENLTQED--PQMVYQSARQEPQGQEHQVDN
       : .::::..::::. ::  :.   :   ... :. .:   :.: ..::::::::: : .:
XP_005 NRSLLAIHQQATGN-GPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSEN
               40         50        60        70        80         

     170       180       190       200       210       220         
pF1KE2 TVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSR
        .::::.  .  .:::::::::::::.:::.:::::     ...:: ..:..: :.:: :
XP_005 LIMEKQL--SPRMQNNEELPTYEEAKVQSQYFRGQQ-----HASVGAAFYVTGVTNQKMR
      90         100       110       120            130       140  

     230       240       250       260       270       280         
pF1KE2 TEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSG------
       :::::.:.: : :. :.::.:..::::::::::::.::.::  .:.: : : ..      
XP_005 TEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPP
            150       160       170       180       190       200  

                     290       300       310       320       330   
pF1KE2 ----------NGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLF
                 ... :  . :: : : . : .. ::::::::::    .: : : :: : :
XP_005 QPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHF
            210       220       230       240       250       260  

           340       350       360       370          380          
pF1KE2 YGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQ---LPFPSTMQQ-HS
       :..      :..       :: ::.  ..::: :::::. .:: :   ::. .  .: ::
XP_005 YSE------HRL------NQPGRTEGQLMRYQHPPEYGA-ARPAQDISLPLSARNSQPHS
                        270       280        290       300         

     390       400                             410                 
pF1KE2 PMSSQTSSASGPL----------------------HSVSLPLP----LP--------MAL
       : :: ::..: ::                      ::. :: :    ::        . :
XP_005 PTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRL
     310       320       330       340       350       360         

                                  420                     430      
pF1KE2 GAP-------------------------QP---P-------PAASPS----QQLGPDAFA
       . :                         ::   :       : :.::    : .  : ::
XP_005 SQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFA
     370       380       390       400       410       420         

        440       450       460       470       480       490      
pF1KE2 IVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESL
       :: :::::::::..::: :.:::.: :... .:.: : :.::.:::::.::::..:::.:
XP_005 IVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREAL
     430       440       450       460       470       480         

        500       510       520       530        540       550     
pF1KE2 DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED-KAAEGHYASQNKEFLK
       .:::::::::::::.::::::::.::::::.::. .:::: :: . . ..  ..:::  .
XP_005 EKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQR
     490       500       510       520       530       540         

         560       570       580       590       600       610     
pF1KE2 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA
       :::::: :::..:...::.:::::: :::::::::.:.::::::..::.::.::::.:::
XP_005 EKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQA
     550       560       570       580       590       600         

         620       630       640       650       660       670     
pF1KE2 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEE
       :.:::.:::::::.:.:::: :::::..:: ::..:: ::.:. :::: ::.::.:::::
XP_005 LVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEE
     610       620       630       640       650       660         

         680       690       700       710       720       730     
pF1KE2 RILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIW
       :::::::::::::::::::...::::..::::.::.::::.:.:: : :: ...:::.: 
XP_005 RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSY-DTALEARIQ
     670       680       690       700       710        720        

         740       750       760       770       780        790    
pF1KE2 QEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDS-SSLRPARSV
       .::::...::.:: :::  ::.:::.:::::::::::::::::. .::.. : .:::.:.
XP_005 KEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSL
      730       740       750       760       770       780        

           800       810       820       830       840       850   
pF1KE2 PSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSA
        ::. :..:  :....::.: . :::...:.::::.:.::: ...    :  .:  :   
XP_005 MSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYR----AEYVPSTP---
      790       800       810       820       830           840    

           860       870       880       890       900       910   
pF1KE2 LSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPA
        : .  .:   :::.::::.: ::::....:                             
XP_005 -SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA
              850       860       870       880       890       900

           920       930       940       950                       
pF1KE2 AKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI                 
                                                                   
XP_005 ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA
              910       920       930       940       950       960

>>NP_001106962 (OMIM: 300410) angiomotin isoform 1 [Homo  (1084 aa)
 initn: 2374 init1: 862 opt: 1884  Z-score: 977.0  bits: 192.3 E(93482): 1.2e-47
Smith-Waterman score: 2643; 52.5% identity (72.6% similar) in 901 aa overlap (87-884:1-871)

         60        70        80        90         100       110    
pF1KE2 EATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAG--TVLQRLIQEQLRYGTPTE
                                     ::.::.  .:  ::::::.:::::::.:.:
NP_001                               MRNSEEQPSGGTTVLQRLLQEQLRYGNPSE
                                             10        20        30

          120       130          140         150       160         
pF1KE2 NMNLLAIQHQATGSAGPAHPT---NNFSSTENLTQED--PQMVYQSARQEPQGQEHQVDN
       : .::::..::::. ::  :.   :   ... :. .:   :.: ..::::::::: : .:
NP_001 NRSLLAIHQQATGN-GPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSEN
               40         50        60        70        80         

     170       180       190       200       210       220         
pF1KE2 TVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSR
        .::::.  .  .:::::::::::::.:::.:::::     ...:: ..:..: :.:: :
NP_001 LIMEKQL--SPRMQNNEELPTYEEAKVQSQYFRGQQ-----HASVGAAFYVTGVTNQKMR
      90         100       110       120            130       140  

     230       240       250       260       270       280         
pF1KE2 TEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSG------
       :::::.:.: : :. :.::.:..::::::::::::.::.::  .:.: : : ..      
NP_001 TEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPP
            150       160       170       180       190       200  

                     290       300       310       320       330   
pF1KE2 ----------NGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLF
                 ... :  . :: : : . : .. ::::::::::    .: : : :: : :
NP_001 QPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHF
            210       220       230       240       250       260  

           340       350       360       370          380          
pF1KE2 YGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQ---LPFPSTMQQ-HS
       :..      :..       :: ::.  ..::: :::::. .:: :   ::. .  .: ::
NP_001 YSE------HRL------NQPGRTEGQLMRYQHPPEYGA-ARPAQDISLPLSARNSQPHS
                        270       280        290       300         

     390       400                             410                 
pF1KE2 PMSSQTSSASGPL----------------------HSVSLPLP----LP--------MAL
       : :: ::..: ::                      ::. :: :    ::        . :
NP_001 PTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRL
     310       320       330       340       350       360         

                                  420                     430      
pF1KE2 GAP-------------------------QP---P-------PAASPS----QQLGPDAFA
       . :                         ::   :       : :.::    : .  : ::
NP_001 SQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFA
     370       380       390       400       410       420         

        440       450       460       470       480       490      
pF1KE2 IVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESL
       :: :::::::::..::: :.:::.: :... .:.: : :.::.:::::.::::..:::.:
NP_001 IVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREAL
     430       440       450       460       470       480         

        500       510       520       530        540       550     
pF1KE2 DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED-KAAEGHYASQNKEFLK
       .:::::::::::::.::::::::.::::::.::. .:::: :: . . ..  ..:::  .
NP_001 EKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQR
     490       500       510       520       530       540         

         560       570       580       590       600       610     
pF1KE2 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA
       :::::: :::..:...::.:::::: :::::::::.:.::::::..::.::.::::.:::
NP_001 EKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQA
     550       560       570       580       590       600         

         620       630       640       650       660       670     
pF1KE2 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEE
       :.:::.:::::::.:.:::: :::::..:: ::..:: ::.:. :::: ::.::.:::::
NP_001 LVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEE
     610       620       630       640       650       660         

         680       690       700       710       720       730     
pF1KE2 RILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIW
       :::::::::::::::::::...::::..::::.::.::::.:.:: : :: ...:::.: 
NP_001 RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSY-DTALEARIQ
     670       680       690       700       710        720        

         740       750       760       770       780        790    
pF1KE2 QEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDS-SSLRPARSV
       .::::...::.:: :::  ::.:::.:::::::::::::::::. .::.. : .:::.:.
NP_001 KEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSL
      730       740       750       760       770       780        

           800       810       820       830       840       850   
pF1KE2 PSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSA
        ::. :..:  :....::.: . :::...:.::::.:.::: ...    :  .:  :   
NP_001 MSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYR----AEYVPSTP---
      790       800       810       820       830           840    

           860       870       880       890       900       910   
pF1KE2 LSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPA
        : .  .:   :::.::::.: ::::....:                             
NP_001 -SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA
              850       860       870       880       890       900

           920       930       940       950                       
pF1KE2 AKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI                 
                                                                   
NP_001 ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA
              910       920       930       940       950       960

>>XP_011529177 (OMIM: 300410) angiomotin isoform X1 [Hom  (1084 aa)
 initn: 2374 init1: 862 opt: 1884  Z-score: 977.0  bits: 192.3 E(93482): 1.2e-47
Smith-Waterman score: 2643; 52.5% identity (72.6% similar) in 901 aa overlap (87-884:1-871)

         60        70        80        90         100       110    
pF1KE2 EATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAG--TVLQRLIQEQLRYGTPTE
                                     ::.::.  .:  ::::::.:::::::.:.:
XP_011                               MRNSEEQPSGGTTVLQRLLQEQLRYGNPSE
                                             10        20        30

          120       130          140         150       160         
pF1KE2 NMNLLAIQHQATGSAGPAHPT---NNFSSTENLTQED--PQMVYQSARQEPQGQEHQVDN
       : .::::..::::. ::  :.   :   ... :. .:   :.: ..::::::::: : .:
XP_011 NRSLLAIHQQATGN-GPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSEN
               40         50        60        70        80         

     170       180       190       200       210       220         
pF1KE2 TVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSR
        .::::.  .  .:::::::::::::.:::.:::::     ...:: ..:..: :.:: :
XP_011 LIMEKQL--SPRMQNNEELPTYEEAKVQSQYFRGQQ-----HASVGAAFYVTGVTNQKMR
      90         100       110       120            130       140  

     230       240       250       260       270       280         
pF1KE2 TEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSG------
       :::::.:.: : :. :.::.:..::::::::::::.::.::  .:.: : : ..      
XP_011 TEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPP
            150       160       170       180       190       200  

                     290       300       310       320       330   
pF1KE2 ----------NGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLF
                 ... :  . :: : : . : .. ::::::::::    .: : : :: : :
XP_011 QPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHF
            210       220       230       240       250       260  

           340       350       360       370          380          
pF1KE2 YGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQ---LPFPSTMQQ-HS
       :..      :..       :: ::.  ..::: :::::. .:: :   ::. .  .: ::
XP_011 YSE------HRL------NQPGRTEGQLMRYQHPPEYGA-ARPAQDISLPLSARNSQPHS
                        270       280        290       300         

     390       400                             410                 
pF1KE2 PMSSQTSSASGPL----------------------HSVSLPLP----LP--------MAL
       : :: ::..: ::                      ::. :: :    ::        . :
XP_011 PTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRL
     310       320       330       340       350       360         

                                  420                     430      
pF1KE2 GAP-------------------------QP---P-------PAASPS----QQLGPDAFA
       . :                         ::   :       : :.::    : .  : ::
XP_011 SQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFA
     370       380       390       400       410       420         

        440       450       460       470       480       490      
pF1KE2 IVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESL
       :: :::::::::..::: :.:::.: :... .:.: : :.::.:::::.::::..:::.:
XP_011 IVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREAL
     430       440       450       460       470       480         

        500       510       520       530        540       550     
pF1KE2 DKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHED-KAAEGHYASQNKEFLK
       .:::::::::::::.::::::::.::::::.::. .:::: :: . . ..  ..:::  .
XP_011 EKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQR
     490       500       510       520       530       540         

         560       570       580       590       600       610     
pF1KE2 EKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQA
       :::::: :::..:...::.:::::: :::::::::.:.::::::..::.::.::::.:::
XP_011 EKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQA
     550       560       570       580       590       600         

         620       630       640       650       660       670     
pF1KE2 LTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEE
       :.:::.:::::::.:.:::: :::::..:: ::..:: ::.:. :::: ::.::.:::::
XP_011 LVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEE
     610       620       630       640       650       660         

         680       690       700       710       720       730     
pF1KE2 RILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIW
       :::::::::::::::::::...::::..::::.::.::::.:.:: : :: ...:::.: 
XP_011 RILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSY-DTALEARIQ
     670       680       690       700       710        720        

         740       750       760       770       780        790    
pF1KE2 QEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDS-SSLRPARSV
       .::::...::.:: :::  ::.:::.:::::::::::::::::. .::.. : .:::.:.
XP_011 KEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSL
      730       740       750       760       770       780        

           800       810       820       830       840       850   
pF1KE2 PSIA-AATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSA
        ::. :..:  :....::.: . :::...:.::::.:.::: ...    :  .:  :   
XP_011 MSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYR----AEYVPSTP---
      790       800       810       820       830           840    

           860       870       880       890       900       910   
pF1KE2 LSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPA
        : .  .:   :::.::::.: ::::....:                             
XP_011 -SPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATA
              850       860       870       880       890       900

           920       930       940       950                       
pF1KE2 AKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI                 
                                                                   
XP_011 ATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVA
              910       920       930       940       950       960




956 residues in 1 query   sequences
65951994 residues in 93482 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Jun 20 10:39:42 2019 done: Thu Jun 20 10:39:44 2019
 Total Scan time:  7.750 Total Display time:  0.220

Function used was FASTA [36.3.4 Apr, 2011]
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