Result of FASTA (omim) for pF1KE2491
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2491, 2353 aa
  1>>>pF1KE2491 2353 - 2353 aa - 2353 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.6361+/-0.000415; mu= 1.4285+/- 0.026
 mean_var=317.1077+/-66.692, 0's: 0 Z-trim(121.4): 275  B-trim: 590 in 1/57
 Lambda= 0.072023
 statistics sampled from 37561 (37844) to 37561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.444), width:  16
 Scan time: 20.700

The best scores are:                                      opt bits E(85289)
NP_066921 (OMIM: 607904,611942,617027) voltage-dep (2353) 16075 1686.0       0
XP_006721026 (OMIM: 607904,611942,617027) PREDICTE (2358) 16015 1679.8       0
NP_001005407 (OMIM: 607904,611942,617027) voltage- (2347) 16005 1678.7       0
XP_005255709 (OMIM: 607904,611942,617027) PREDICTE (2347) 15910 1668.8       0
XP_016879308 (OMIM: 607904,611942,617027) PREDICTE (2345) 14988 1573.0       0
XP_011521026 (OMIM: 607904,611942,617027) PREDICTE (2176) 14751 1548.4       0
XP_006721027 (OMIM: 607904,611942,617027) PREDICTE (2342) 13397 1407.7       0
XP_006721028 (OMIM: 607904,611942,617027) PREDICTE (2336) 13325 1400.2       0
XP_016879310 (OMIM: 607904,611942,617027) PREDICTE (1691) 10944 1152.7       0
XP_016879309 (OMIM: 607904,611942,617027) PREDICTE (1691) 10944 1152.7       0
XP_006721031 (OMIM: 607904,611942,617027) PREDICTE (1612) 10453 1101.7       0
XP_006721030 (OMIM: 607904,611942,617027) PREDICTE (1618) 10453 1101.7       0
XP_011521029 (OMIM: 607904,611942,617027) PREDICTE (1283) 6722 713.9 3.1e-204
NP_938194 (OMIM: 604065,616795) voltage-dependent  (2321) 5751 613.2 1.2e-173
NP_938191 (OMIM: 604065,616795) voltage-dependent  (2366) 5726 610.7 7.1e-173
NP_938192 (OMIM: 604065,616795) voltage-dependent  (2273) 5684 606.3 1.4e-171
NP_001243263 (OMIM: 604065,616795) voltage-depende (2194) 5634 601.1 5.1e-170
NP_001243253 (OMIM: 604065,616795) voltage-depende (2314) 5492 586.3 1.5e-165
NP_938200 (OMIM: 604065,616795) voltage-dependent  (2266) 5411 577.9 4.9e-163
NP_001243256 (OMIM: 604065,616795) voltage-depende (2277) 4867 521.4 5.1e-146
NP_001243257 (OMIM: 604065,616795) voltage-depende (2259) 4863 521.0 6.8e-146
NP_938198 (OMIM: 604065,616795) voltage-dependent  (2284) 4140 445.8 2.8e-123
NP_001243262 (OMIM: 604065,616795) voltage-depende (2205) 4137 445.5 3.4e-123
NP_061496 (OMIM: 604065,616795) voltage-dependent  (2377) 4117 443.5 1.5e-122
NP_001243254 (OMIM: 604065,616795) voltage-depende (2291) 4111 442.8 2.3e-122
NP_938199 (OMIM: 604065,616795) voltage-dependent  (2332) 4106 442.3 3.3e-122
NP_001243290 (OMIM: 604065,616795) voltage-depende (2246) 3906 421.5 5.8e-116
NP_001243259 (OMIM: 604065,616795) voltage-depende (2239) 3847 415.4  4e-114
NP_001243289 (OMIM: 604065,616795) voltage-depende (2248) 3811 411.7 5.4e-113
NP_001243258 (OMIM: 604065,616795) voltage-depende (2250) 3751 405.4 4.1e-111
NP_001243260 (OMIM: 604065,616795) voltage-depende (2232) 3723 402.5 3.1e-110
NP_001243288 (OMIM: 604065,616795) voltage-depende (2257) 3694 399.5 2.5e-109
NP_001243255 (OMIM: 604065,616795) voltage-depende (2287) 3693 399.4 2.7e-109
XP_016884525 (OMIM: 608230) PREDICTED: voltage-dep (1605) 3617 391.4 4.9e-107
NP_001003406 (OMIM: 608230) voltage-dependent T-ty (2188) 3617 391.5 6.2e-107
NP_066919 (OMIM: 608230) voltage-dependent T-type  (2223) 3617 391.5 6.3e-107
XP_016884526 (OMIM: 608230) PREDICTED: voltage-dep (1593) 3595 389.1 2.4e-106
XP_016884524 (OMIM: 608230) PREDICTED: voltage-dep (1606) 3595 389.1 2.4e-106
NP_938193 (OMIM: 604065,616795) voltage-dependent  (2298) 3577 387.3 1.2e-105
NP_938406 (OMIM: 604065,616795) voltage-dependent  (2343) 3552 384.8 7.1e-105
NP_938201 (OMIM: 604065,616795) voltage-dependent  (2250) 3510 380.4 1.4e-103
NP_938190 (OMIM: 604065,616795) voltage-dependent  (2171) 3460 375.2  5e-102
NP_938202 (OMIM: 604065,616795) voltage-dependent  (2243) 3237 352.0 4.9e-95
XP_006722224 (OMIM: 604065,616795) PREDICTED: volt (2244) 1966 219.9 2.8e-55
NP_938196 (OMIM: 604065,616795) voltage-dependent  (2261) 1966 219.9 2.8e-55
NP_938197 (OMIM: 604065,616795) voltage-dependent  (2306) 1956 218.9 5.8e-55
XP_006722223 (OMIM: 604065,616795) PREDICTED: volt (2268) 1937 216.9 2.3e-54
NP_001243261 (OMIM: 604065,616795) voltage-depende (2227) 1577 179.5 4.1e-43
XP_016861142 (OMIM: 604385,615548,615552) PREDICTE (1259)  957 114.9 6.5e-24
XP_011531623 (OMIM: 604385,615548,615552) PREDICTE (1570)  957 115.0 7.7e-24


>>NP_066921 (OMIM: 607904,611942,617027) voltage-depende  (2353 aa)
 initn: 16075 init1: 16075 opt: 16075  Z-score: 9036.2  bits: 1686.0 E(85289):    0
Smith-Waterman score: 16075; 99.9% identity (100.0% similar) in 2353 aa overlap (1-2353:1-2353)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KE2 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KE2 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KE2 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KE2 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KE2 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KE2 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KE2 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KE2 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASDPADEE
       ::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_066 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEE
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KE2 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KE2 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KE2 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KE2 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS
             2290      2300      2310      2320      2330      2340

             2350   
pF1KE2 ATPAPGGGADDPV
       :::::::::::::
NP_066 ATPAPGGGADDPV
             2350   

>>XP_006721026 (OMIM: 607904,611942,617027) PREDICTED: v  (2358 aa)
 initn: 16023 init1: 10894 opt: 16015  Z-score: 9002.5  bits: 1679.8 E(85289):    0
Smith-Waterman score: 16015; 99.5% identity (99.7% similar) in 2358 aa overlap (1-2353:1-2358)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
             1510      1520      1530      1540      1550      1560

             1570      1580       1590          1600      1610     
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRS-TFPSP----EAQRRPYYADYSPTRRSIHSLCT
       ::::::::::::::::::::::::::: ..:      :::::::::::::::::::::::
XP_006 CRQHQEAEEARRREEKRLRRLERRRRSKALPVAVAVAEAQRRPYYADYSPTRRSIHSLCT
             1570      1580      1590      1600      1610      1620

        1620      1630      1640      1650      1660      1670     
pF1KE2 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR
             1630      1640      1650      1660      1670      1680

        1680      1690      1700      1710      1720      1730     
pF1KE2 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM
             1690      1700      1710      1720      1730      1740

        1740      1750      1760      1770      1780      1790     
pF1KE2 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG
             1750      1760      1770      1780      1790      1800

        1800      1810      1820      1830      1840      1850     
pF1KE2 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV
             1810      1820      1830      1840      1850      1860

        1860      1870      1880      1890      1900      1910     
pF1KE2 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV
             1870      1880      1890      1900      1910      1920

        1920      1930      1940      1950      1960      1970     
pF1KE2 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES
             1930      1940      1950      1960      1970      1980

        1980      1990      2000      2010      2020      2030     
pF1KE2 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL
             1990      2000      2010      2020      2030      2040

        2040      2050      2060      2070      2080      2090     
pF1KE2 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASD
       :::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_006 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASD
             2050      2060      2070      2080      2090      2100

        2100      2110      2120      2130      2140      2150     
pF1KE2 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR
             2110      2120      2130      2140      2150      2160

        2160      2170      2180      2190      2200      2210     
pF1KE2 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT
             2170      2180      2190      2200      2210      2220

        2220      2230      2240      2250      2260      2270     
pF1KE2 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV
             2230      2240      2250      2260      2270      2280

        2280      2290      2300      2310      2320      2330     
pF1KE2 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK
             2290      2300      2310      2320      2330      2340

        2340      2350   
pF1KE2 PGSPSATPAPGGGADDPV
       ::::::::::::::::::
XP_006 PGSPSATPAPGGGADDPV
             2350        

>>NP_001005407 (OMIM: 607904,611942,617027) voltage-depe  (2347 aa)
 initn: 10891 init1: 10891 opt: 16005  Z-score: 8997.0  bits: 1678.7 E(85289):    0
Smith-Waterman score: 16005; 99.6% identity (99.7% similar) in 2353 aa overlap (1-2353:1-2347)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD
       ::::::::::::::::::::::::::      .:::::::::::::::::::::::::::
NP_001 CRQHQEAEEARRREEKRLRRLERRRR------KAQRRPYYADYSPTRRSIHSLCTSHYLD
             1570      1580            1590      1600      1610    

             1630      1640      1650      1660      1670      1680
pF1KE2 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR
         1620      1630      1640      1650      1660      1670    

             1690      1700      1710      1720      1730      1740
pF1KE2 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
         1680      1690      1700      1710      1720      1730    

             1750      1760      1770      1780      1790      1800
pF1KE2 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT
         1740      1750      1760      1770      1780      1790    

             1810      1820      1830      1840      1850      1860
pF1KE2 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM
         1800      1810      1820      1830      1840      1850    

             1870      1880      1890      1900      1910      1920
pF1KE2 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS
         1860      1870      1880      1890      1900      1910    

             1930      1940      1950      1960      1970      1980
pF1KE2 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ
         1920      1930      1940      1950      1960      1970    

             1990      2000      2010      2020      2030      2040
pF1KE2 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP
         1980      1990      2000      2010      2020      2030    

             2050      2060      2070      2080      2090      2100
pF1KE2 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASDPADEE
       ::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_001 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEE
         2040      2050      2060      2070      2080      2090    

             2110      2120      2130      2140      2150      2160
pF1KE2 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL
         2100      2110      2120      2130      2140      2150    

             2170      2180      2190      2200      2210      2220
pF1KE2 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT
         2160      2170      2180      2190      2200      2210    

             2230      2240      2250      2260      2270      2280
pF1KE2 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP
         2220      2230      2240      2250      2260      2270    

             2290      2300      2310      2320      2330      2340
pF1KE2 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS
         2280      2290      2300      2310      2320      2330    

             2350   
pF1KE2 ATPAPGGGADDPV
       :::::::::::::
NP_001 ATPAPGGGADDPV
         2340       

>>XP_005255709 (OMIM: 607904,611942,617027) PREDICTED: v  (2347 aa)
 initn: 13528 init1: 10894 opt: 15910  Z-score: 8943.6  bits: 1668.8 E(85289):    0
Smith-Waterman score: 15910; 99.1% identity (99.2% similar) in 2358 aa overlap (1-2353:1-2347)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
             1510      1520      1530      1540      1550      1560

             1570      1580       1590          1600      1610     
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRS-TFPSP----EAQRRPYYADYSPTRRSIHSLCT
       ::::::::::::::::::::::::::: ..:      :::::::::::::::::::::::
XP_005 CRQHQEAEEARRREEKRLRRLERRRRSKALPVAVAVAEAQRRPYYADYSPTRRSIHSLCT
             1570      1580      1590      1600      1610      1620

        1620      1630      1640      1650      1660      1670     
pF1KE2 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR
             1630      1640      1650      1660      1670      1680

        1680      1690      1700      1710      1720      1730     
pF1KE2 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM
             1690      1700      1710      1720      1730      1740

        1740      1750      1760      1770      1780      1790     
pF1KE2 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG
             1750      1760      1770      1780      1790      1800

        1800      1810      1820      1830      1840      1850     
pF1KE2 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV
             1810      1820      1830      1840      1850      1860

        1860      1870      1880      1890      1900      1910     
pF1KE2 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV
             1870      1880      1890      1900      1910      1920

        1920      1930      1940      1950      1960      1970     
pF1KE2 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES
       :::::::::::::::::::::::::::::::::::::::::::::::           ::
XP_005 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPL-----------ES
             1930      1940      1950      1960                    

        1980      1990      2000      2010      2020      2030     
pF1KE2 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL
    1970      1980      1990      2000      2010      2020         

        2040      2050      2060      2070      2080      2090     
pF1KE2 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASD
       :::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_005 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASD
    2030      2040      2050      2060      2070      2080         

        2100      2110      2120      2130      2140      2150     
pF1KE2 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR
    2090      2100      2110      2120      2130      2140         

        2160      2170      2180      2190      2200      2210     
pF1KE2 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT
    2150      2160      2170      2180      2190      2200         

        2220      2230      2240      2250      2260      2270     
pF1KE2 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV
    2210      2220      2230      2240      2250      2260         

        2280      2290      2300      2310      2320      2330     
pF1KE2 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK
    2270      2280      2290      2300      2310      2320         

        2340      2350   
pF1KE2 PGSPSATPAPGGGADDPV
       ::::::::::::::::::
XP_005 PGSPSATPAPGGGADDPV
    2330      2340       

>>XP_016879308 (OMIM: 607904,611942,617027) PREDICTED: v  (2345 aa)
 initn: 14986 init1: 9857 opt: 14988  Z-score: 8425.9  bits: 1573.0 E(85289):    0
Smith-Waterman score: 15895; 99.0% identity (99.2% similar) in 2358 aa overlap (1-2353:1-2345)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       :::::::::::::::::             ::::::::::::::::::::::::::::::
XP_016 RPCEDVECGSERCNILE-------------MVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130                    140       150       160       

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       170       180       190       200       210       220       

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       230       240       250       260       270       280       

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       290       300       310       320       330       340       

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       350       360       370       380       390       400       

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       410       420       430       440       450       460       

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       470       480       490       500       510       520       

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       530       540       550       560       570       580       

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       590       600       610       620       630       640       

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       650       660       670       680       690       700       

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       710       720       730       740       750       760       

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       770       780       790       800       810       820       

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       830       840       850       860       870       880       

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       890       900       910       920       930       940       

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       950       960       970       980       990      1000       

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
      1010      1020      1030      1040      1050      1060       

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
      1070      1080      1090      1100      1110      1120       

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
      1130      1140      1150      1160      1170      1180       

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
      1190      1200      1210      1220      1230      1240       

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
      1250      1260      1270      1280      1290      1300       

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
      1310      1320      1330      1340      1350      1360       

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
      1370      1380      1390      1400      1410      1420       

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
      1430      1440      1450      1460      1470      1480       

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
      1490      1500      1510      1520      1530      1540       

             1570      1580       1590          1600      1610     
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRS-TFPSP----EAQRRPYYADYSPTRRSIHSLCT
       ::::::::::::::::::::::::::: ..:      :::::::::::::::::::::::
XP_016 CRQHQEAEEARRREEKRLRRLERRRRSKALPVAVAVAEAQRRPYYADYSPTRRSIHSLCT
      1550      1560      1570      1580      1590      1600       

        1620      1630      1640      1650      1660      1670     
pF1KE2 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR
      1610      1620      1630      1640      1650      1660       

        1680      1690      1700      1710      1720      1730     
pF1KE2 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM
      1670      1680      1690      1700      1710      1720       

        1740      1750      1760      1770      1780      1790     
pF1KE2 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG
      1730      1740      1750      1760      1770      1780       

        1800      1810      1820      1830      1840      1850     
pF1KE2 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV
      1790      1800      1810      1820      1830      1840       

        1860      1870      1880      1890      1900      1910     
pF1KE2 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV
      1850      1860      1870      1880      1890      1900       

        1920      1930      1940      1950      1960      1970     
pF1KE2 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES
      1910      1920      1930      1940      1950      1960       

        1980      1990      2000      2010      2020      2030     
pF1KE2 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL
      1970      1980      1990      2000      2010      2020       

        2040      2050      2060      2070      2080      2090     
pF1KE2 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASD
       :::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASD
      2030      2040      2050      2060      2070      2080       

        2100      2110      2120      2130      2140      2150     
pF1KE2 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR
      2090      2100      2110      2120      2130      2140       

        2160      2170      2180      2190      2200      2210     
pF1KE2 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT
      2150      2160      2170      2180      2190      2200       

        2220      2230      2240      2250      2260      2270     
pF1KE2 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV
      2210      2220      2230      2240      2250      2260       

        2280      2290      2300      2310      2320      2330     
pF1KE2 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK
      2270      2280      2290      2300      2310      2320       

        2340      2350   
pF1KE2 PGSPSATPAPGGGADDPV
       ::::::::::::::::::
XP_016 PGSPSATPAPGGGADDPV
      2330      2340     

>>XP_011521026 (OMIM: 607904,611942,617027) PREDICTED: v  (2176 aa)
 initn: 14759 init1: 9630 opt: 14751  Z-score: 8293.2  bits: 1548.4 E(85289):    0
Smith-Waterman score: 14751; 99.5% identity (99.7% similar) in 2176 aa overlap (183-2353:1-2176)

            160       170       180       190       200       210  
pF1KE2 IKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINR
                                     ::::::::::::::::::::::::::::::
XP_011                               MMEYSLDGHNVSLSAIRTVRVLRPLRAINR
                                             10        20        30

            220       230       240       250       260       270  
pF1KE2 VPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNL
               40        50        60        70        80        90

            280       290       300       310       320       330  
pF1KE2 TFLRPYYQTEEGEENPFICSSRRDNGMQKCSHIPGRRELRMPCTLGWEAYTQPQAEGVGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFLRPYYQTEEGEENPFICSSRRDNGMQKCSHIPGRRELRMPCTLGWEAYTQPQAEGVGA
              100       110       120       130       140       150

            340       350       360       370       380       390  
pF1KE2 ARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHS
              160       170       180       190       200       210

            400       410       420       430       440       450  
pF1KE2 FYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRARHLSNDSTLASFSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRARHLSNDSTLASFSE
              220       230       240       250       260       270

            460       470       480       490       500       510  
pF1KE2 PGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTA
              280       290       300       310       320       330

            520       530       540       550       560       570  
pF1KE2 SVHHLVYHHHHHHHHHYHFSHGSPRRPGPEPGACDTRLVRAGAPPSPPSPGRGPPDAESV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVHHLVYHHHHHHHHHYHFSHGSPRRPGPEPGACDTRLVRAGAPPSPPSPGRGPPDAESV
              340       350       360       370       380       390

            580       590       600       610       620       630  
pF1KE2 HSIYHADCHIEGPQERARVAHAAATAAASLRLATGLGTMNYPTILPSGVGSGKGSTSPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSIYHADCHIEGPQERARVAHAAATAAASLRLATGLGTMNYPTILPSGVGSGKGSTSPGP
              400       410       420       430       440       450

            640       650       660       670       680       690  
pF1KE2 KGKWAGGPPGTGGHGPLSLNSPDPYEKIPHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGT
       :::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_011 KGKWAGGPPGTGGHGPLSLNSPDPYEKIPHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGT
              460       470       480       490       500       510

            700       710       720       730       740       750  
pF1KE2 LTCELKSCPYCTRALEDPEGELSGSESGDSDGRGVYEFTQDVRHGDRWDPTRPPRATDTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTCELKSCPYCTRALEDPEGELSGSESGDSDGRGVYEFTQDVRHGDRWDPTRPPRATDTP
              520       530       540       550       560       570

            760       770       780       790       800       810  
pF1KE2 GPGPGSPQRRAQQRAAPGEPGWMGRLWVTFSGKLRRIVDSKYFSRGIMMAILVNTLSMGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPGPGSPQRRAQQRAAPGEPGWMGRLWVTFSGKLRRIVDSKYFSRGIMMAILVNTLSMGV
              580       590       600       610       620       630

            820       830       840       850       860       870  
pF1KE2 EYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEI
              640       650       660       670       680       690

            880       890       900       910       920       930  
pF1KE2 VGQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSIL
              700       710       720       730       740       750

            940       950       960       970       980       990  
pF1KE2 GMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAA
              760       770       780       790       800       810

           1000      1010      1020      1030      1040      1050  
pF1KE2 LYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSVHFEEDFHKLRELQTTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSVHFEEDFHKLRELQTTE
              820       830       840       850       860       870

           1060      1070      1080      1090      1100      1110  
pF1KE2 LKMCSLAVTPNGHLEGRGSLSPPLIMCTAATPMPTPKSSPFLDAAPSLPDSRRGSSSSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKMCSLAVTPNGHLEGRGSLSPPLIMCTAATPMPTPKSSPFLDAAPSLPDSRRGSSSSGD
              880       890       900       910       920       930

           1120      1130      1140      1150      1160      1170  
pF1KE2 PPLGDQKPPASLRSSPCAPWGPSGAWSSRRSSWSSLGRAPSLKRRGQCGERESLLSGEGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLGDQKPPASLRSSPCAPWGPSGAWSSRRSSWSSLGRAPSLKRRGQCGERESLLSGEGK
              940       950       960       970       980       990

           1180      1190      1200      1210      1220      1230  
pF1KE2 GSTDDEAEDGRAAPGPRATPLRRAESLDPRPLRPAALPPTKCRDRDGQVVALPSDFFLRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSTDDEAEDGRAAPGPRATPLRRAESLDPRPLRPAALPPTKCRDRDGQVVALPSDFFLRI
             1000      1010      1020      1030      1040      1050

           1240      1250      1260      1270      1280      1290  
pF1KE2 DSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQNRFRVSCQKVIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQNRFRVSCQKVIT
             1060      1070      1080      1090      1100      1110

           1300      1310      1320      1330      1340      1350  
pF1KE2 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGL
             1120      1130      1140      1150      1160      1170

           1360      1370      1380      1390      1400      1410  
pF1KE2 LSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISR
             1180      1190      1200      1210      1220      1230

           1420      1430      1440      1450      1460      1470  
pF1KE2 APGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQ
             1240      1250      1260      1270      1280      1290

           1480      1490      1500      1510      1520      1530  
pF1KE2 CRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWML
             1300      1310      1320      1330      1340      1350

           1540      1550      1560      1570      1580       1590 
pF1KE2 LYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRS-TFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ..: 
XP_011 LYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRSKALPV
             1360      1370      1380      1390      1400      1410

                1600      1610      1620      1630      1640       
pF1KE2 P----EAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDE
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVAVAEAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDE
             1420      1430      1440      1450      1460      1470

      1650      1660      1670      1680      1690      1700       
pF1KE2 ALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAAL
             1480      1490      1500      1510      1520      1530

      1710      1720      1730      1740      1750      1760       
pF1KE2 PINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALG
             1540      1550      1560      1570      1580      1590

      1770      1780      1790      1800      1810      1820       
pF1KE2 VELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSREDKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSREDKH
             1600      1610      1620      1630      1640      1650

      1830      1840      1850      1860      1870      1880       
pF1KE2 CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQG
             1660      1670      1680      1690      1700      1710

      1890      1900      1910      1920      1930      1940       
pF1KE2 PGSARRVDADRPPLPQESPGARDAPNLVARKVSVSRMLSLPNDSYMFRPVVPASAPHPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSARRVDADRPPLPQESPGARDAPNLVARKVSVSRMLSLPNDSYMFRPVVPASAPHPRP
             1720      1730      1740      1750      1760      1770

      1950      1960      1970      1980      1990      2000       
pF1KE2 LQEVEMETYGAGTPLGSVASVHSPPAESCASLQIPLAVSSPARSGEPLHALSPRGTARSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEVEMETYGAGTPLGSVASVHSPPAESCASLQIPLAVSSPARSGEPLHALSPRGTARSP
             1780      1790      1800      1810      1820      1830

      2010      2020      2030      2040      2050      2060       
pF1KE2 SLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKTPVRPVTQGGSLQSPPRSPRPASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKTPVRPVTQGGSLQSPPRSPRPASV
             1840      1850      1860      1870      1880      1890

      2070      2080      2090      2100      2110      2120       
pF1KE2 RTRKHTFGQHCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAG
       :::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRKHTFGQRCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAG
             1900      1910      1920      1930      1940      1950

      2130      2140      2150      2160      2170      2180       
pF1KE2 GERDLRRLYSVDAQGFLDKPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGARRKKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERDLRRLYSVDAQGFLDKPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGARRKKKM
             1960      1970      1980      1990      2000      2010

      2190      2200      2210      2220      2230      2240       
pF1KE2 SPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAGGDPAAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAGGDPAAK
             2020      2030      2040      2050      2060      2070

      2250      2260      2270      2280      2290      2300       
pF1KE2 GERWGQASCRAEHLTVPSFAFEPLDLGVPSGDPFLDGSHSVTPESRASSSGAIVPLEPPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERWGQASCRAEHLTVPSFAFEPLDLGVPSGDPFLDGSHSVTPESRASSSGAIVPLEPPE
             2080      2090      2100      2110      2120      2130

      2310      2320      2330      2340      2350   
pF1KE2 SEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPSATPAPGGGADDPV
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPSATPAPGGGADDPV
             2140      2150      2160      2170      

>>XP_006721027 (OMIM: 607904,611942,617027) PREDICTED: v  (2342 aa)
 initn: 13385 init1: 13385 opt: 13397  Z-score: 7532.4  bits: 1407.7 E(85289):    0
Smith-Waterman score: 15970; 99.4% identity (99.5% similar) in 2353 aa overlap (1-2353:1-2342)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KE2 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KE2 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KE2 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KE2 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KE2 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KE2 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_006 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPL-----------ESCASLQ
             1930      1940      1950      1960                    

             1990      2000      2010      2020      2030      2040
pF1KE2 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP
    1970      1980      1990      2000      2010      2020         

             2050      2060      2070      2080      2090      2100
pF1KE2 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASDPADEE
       ::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_006 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEE
    2030      2040      2050      2060      2070      2080         

             2110      2120      2130      2140      2150      2160
pF1KE2 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL
    2090      2100      2110      2120      2130      2140         

             2170      2180      2190      2200      2210      2220
pF1KE2 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT
    2150      2160      2170      2180      2190      2200         

             2230      2240      2250      2260      2270      2280
pF1KE2 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP
    2210      2220      2230      2240      2250      2260         

             2290      2300      2310      2320      2330      2340
pF1KE2 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS
    2270      2280      2290      2300      2310      2320         

             2350   
pF1KE2 ATPAPGGGADDPV
       :::::::::::::
XP_006 ATPAPGGGADDPV
    2330      2340  

>>XP_006721028 (OMIM: 607904,611942,617027) PREDICTED: v  (2336 aa)
 initn: 13525 init1: 10891 opt: 13325  Z-score: 7492.0  bits: 1400.2 E(85289):    0
Smith-Waterman score: 15900; 99.2% identity (99.3% similar) in 2353 aa overlap (1-2353:1-2336)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD
       ::::::::::::::::::::::::::      .:::::::::::::::::::::::::::
XP_006 CRQHQEAEEARRREEKRLRRLERRRR------KAQRRPYYADYSPTRRSIHSLCTSHYLD
             1570      1580            1590      1600      1610    

             1630      1640      1650      1660      1670      1680
pF1KE2 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR
         1620      1630      1640      1650      1660      1670    

             1690      1700      1710      1720      1730      1740
pF1KE2 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
         1680      1690      1700      1710      1720      1730    

             1750      1760      1770      1780      1790      1800
pF1KE2 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT
         1740      1750      1760      1770      1780      1790    

             1810      1820      1830      1840      1850      1860
pF1KE2 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM
         1800      1810      1820      1830      1840      1850    

             1870      1880      1890      1900      1910      1920
pF1KE2 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS
         1860      1870      1880      1890      1900      1910    

             1930      1940      1950      1960      1970      1980
pF1KE2 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_006 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPL-----------ESCASLQ
         1920      1930      1940      1950                 1960   

             1990      2000      2010      2020      2030      2040
pF1KE2 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP
          1970      1980      1990      2000      2010      2020   

             2050      2060      2070      2080      2090      2100
pF1KE2 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASDPADEE
       ::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_006 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEE
          2030      2040      2050      2060      2070      2080   

             2110      2120      2130      2140      2150      2160
pF1KE2 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL
          2090      2100      2110      2120      2130      2140   

             2170      2180      2190      2200      2210      2220
pF1KE2 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT
          2150      2160      2170      2180      2190      2200   

             2230      2240      2250      2260      2270      2280
pF1KE2 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP
          2210      2220      2230      2240      2250      2260   

             2290      2300      2310      2320      2330      2340
pF1KE2 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS
          2270      2280      2290      2300      2310      2320   

             2350   
pF1KE2 ATPAPGGGADDPV
       :::::::::::::
XP_006 ATPAPGGGADDPV
          2330      

>>XP_016879310 (OMIM: 607904,611942,617027) PREDICTED: v  (1691 aa)
 initn: 10932 init1: 10932 opt: 10944  Z-score: 6156.9  bits: 1152.7 E(85289):    0
Smith-Waterman score: 10944; 99.0% identity (99.4% similar) in 1612 aa overlap (1-1609:1-1612)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590         1600      1610       
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQ---RRPYYADYSPTRRSIHSLCTSH
       :::::::::::::::::::::::::::::::: ..   ..:      :.:::        
XP_016 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPGGEWSLQEPGAPGGPPARRSWPPSPQRP
             1570      1580      1590      1600      1610      1620

      1620      1630      1640      1650      1660      1670       
pF1KE2 YLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFF
                                                                   
XP_016 SAGPTMPTTRPRAAPFTRCAPATISTSSSPSSSVSTSSPCPWSTITNPSRWTRPSSTATT
             1630      1640      1650      1660      1670      1680

>>XP_016879309 (OMIM: 607904,611942,617027) PREDICTED: v  (1691 aa)
 initn: 10932 init1: 10932 opt: 10944  Z-score: 6156.9  bits: 1152.7 E(85289):    0
Smith-Waterman score: 10944; 99.0% identity (99.4% similar) in 1612 aa overlap (1-1609:1-1612)

               10        20        30        40        50        60
pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
       :::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590         1600      1610       
pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQ---RRPYYADYSPTRRSIHSLCTSH
       :::::::::::::::::::::::::::::::: ..   ..:      :.:::        
XP_016 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPGGEWSLQEPGAPGGPPARRSWPPSPQRP
             1570      1580      1590      1600      1610      1620

      1620      1630      1640      1650      1660      1670       
pF1KE2 YLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFF
                                                                   
XP_016 SAGPTMPTTRPRAAPFTRCAPATISTSSSPSSSVSTSSPCPWSTITNPSRWTRPSSTATT
             1630      1640      1650      1660      1670      1680




2353 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 21:00:09 2016 done: Mon Nov  7 21:00:12 2016
 Total Scan time: 20.700 Total Display time:  1.550

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com