Result of FASTA (omim) for pF1KB4546
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4546, 3460 aa
  1>>>pF1KB4546     3460 - 3460 aa - 3460 aa
Library: /omim/omim.rfq.tfa
  61265892 residues in 86068 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2231+/-0.000673; mu= 16.7871+/- 0.041
 mean_var=114.6172+/-22.824, 0's: 0 Z-trim(106.8): 121  B-trim: 59 in 2/48
 Lambda= 0.119798
 statistics sampled from 14898 (14992) to 14898 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.486), E-opt: 0.2 (0.174), width:  16
 Scan time: 19.150

The best scores are:                                      opt bits E(86068)
NP_005036 (OMIM: 257320,600512,600514,616436) reel (3460) 24293 4212.4       0
NP_774959 (OMIM: 257320,600512,600514,616436) reel (3458) 24269 4208.2       0
NP_006099 (OMIM: 604989) spondin-1 precursor [Homo ( 807)  264 59.1 3.8e-07


>>NP_005036 (OMIM: 257320,600512,600514,616436) reelin i  (3460 aa)
 initn: 24293 init1: 24293 opt: 24293  Z-score: 22684.1  bits: 4212.4 E(86068):    0
Smith-Waterman score: 24293; 100.0% identity (100.0% similar) in 3460 aa overlap (1-3460:1-3460)

               10        20        30        40        50        60
pF1KB4 MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB4 GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB4 RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB4 WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB4 NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB4 SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB4 VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB4 WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB4 CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB4 HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB4 EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB4 SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB4 ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB4 QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB4 EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB4 LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB4 SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB4 VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB4 RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB4 SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB4 YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB4 SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB4 TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB4 PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB4 YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KB4 ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KB4 YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KB4 LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KB4 GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KB4 ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KB4 SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KB4 PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KB4 GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440      2450      2460
pF1KB4 VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
             2410      2420      2430      2440      2450      2460

             2470      2480      2490      2500      2510      2520
pF1KB4 PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
             2470      2480      2490      2500      2510      2520

             2530      2540      2550      2560      2570      2580
pF1KB4 NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
             2530      2540      2550      2560      2570      2580

             2590      2600      2610      2620      2630      2640
pF1KB4 YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
             2590      2600      2610      2620      2630      2640

             2650      2660      2670      2680      2690      2700
pF1KB4 WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
             2650      2660      2670      2680      2690      2700

             2710      2720      2730      2740      2750      2760
pF1KB4 MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
             2710      2720      2730      2740      2750      2760

             2770      2780      2790      2800      2810      2820
pF1KB4 VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
             2770      2780      2790      2800      2810      2820

             2830      2840      2850      2860      2870      2880
pF1KB4 YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
             2830      2840      2850      2860      2870      2880

             2890      2900      2910      2920      2930      2940
pF1KB4 NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
             2890      2900      2910      2920      2930      2940

             2950      2960      2970      2980      2990      3000
pF1KB4 DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
             2950      2960      2970      2980      2990      3000

             3010      3020      3030      3040      3050      3060
pF1KB4 VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
             3010      3020      3030      3040      3050      3060

             3070      3080      3090      3100      3110      3120
pF1KB4 TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
             3070      3080      3090      3100      3110      3120

             3130      3140      3150      3160      3170      3180
pF1KB4 QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
             3130      3140      3150      3160      3170      3180

             3190      3200      3210      3220      3230      3240
pF1KB4 NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
             3190      3200      3210      3220      3230      3240

             3250      3260      3270      3280      3290      3300
pF1KB4 CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
             3250      3260      3270      3280      3290      3300

             3310      3320      3330      3340      3350      3360
pF1KB4 YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
             3310      3320      3330      3340      3350      3360

             3370      3380      3390      3400      3410      3420
pF1KB4 LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
             3370      3380      3390      3400      3410      3420

             3430      3440      3450      3460
pF1KB4 DHVEVVLVSTRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
       ::::::::::::::::::::::::::::::::::::::::
NP_005 DHVEVVLVSTRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
             3430      3440      3450      3460

>>NP_774959 (OMIM: 257320,600512,600514,616436) reelin i  (3458 aa)
 initn: 24062 init1: 24062 opt: 24269  Z-score: 22661.7  bits: 4208.2 E(86068):    0
Smith-Waterman score: 24269; 99.9% identity (99.9% similar) in 3460 aa overlap (1-3460:1-3458)

               10        20        30        40        50        60
pF1KB4 MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB4 GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB4 RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB4 WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB4 NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB4 SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB4 VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB4 WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB4 CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB4 HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB4 EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB4 SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB4 ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB4 QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB4 EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB4 LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB4 SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB4 VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB4 RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB4 SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB4 YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB4 SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB4 TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB4 PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB4 YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KB4 ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KB4 YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KB4 LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KB4 GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KB4 ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KB4 SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KB4 PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KB4 GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440      2450      2460
pF1KB4 VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
             2410      2420      2430      2440      2450      2460

             2470      2480      2490      2500      2510      2520
pF1KB4 PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
             2470      2480      2490      2500      2510      2520

             2530      2540      2550      2560      2570      2580
pF1KB4 NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
             2530      2540      2550      2560      2570      2580

             2590      2600      2610      2620      2630      2640
pF1KB4 YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
             2590      2600      2610      2620      2630      2640

             2650      2660      2670      2680      2690      2700
pF1KB4 WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
             2650      2660      2670      2680      2690      2700

             2710      2720      2730      2740      2750      2760
pF1KB4 MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
             2710      2720      2730      2740      2750      2760

             2770      2780      2790      2800      2810      2820
pF1KB4 VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
             2770      2780      2790      2800      2810      2820

             2830      2840      2850      2860      2870      2880
pF1KB4 YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
             2830      2840      2850      2860      2870      2880

             2890      2900      2910      2920      2930      2940
pF1KB4 NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
             2890      2900      2910      2920      2930      2940

             2950      2960      2970      2980      2990      3000
pF1KB4 DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
             2950      2960      2970      2980      2990      3000

             3010      3020      3030      3040      3050      3060
pF1KB4 VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
             3010      3020      3030      3040      3050      3060

             3070      3080      3090      3100      3110      3120
pF1KB4 TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
             3070      3080      3090      3100      3110      3120

             3130      3140      3150      3160      3170      3180
pF1KB4 QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
             3130      3140      3150      3160      3170      3180

             3190      3200      3210      3220      3230      3240
pF1KB4 NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
             3190      3200      3210      3220      3230      3240

             3250      3260      3270      3280      3290      3300
pF1KB4 CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
             3250      3260      3270      3280      3290      3300

             3310      3320      3330      3340      3350      3360
pF1KB4 YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
             3310      3320      3330      3340      3350      3360

             3370      3380      3390      3400      3410      3420
pF1KB4 LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
             3370      3380      3390      3400      3410      3420

             3430      3440      3450      3460
pF1KB4 DHVEVVLVSTRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
       :::::::  :::::::::::::::::::::::::::::::
NP_774 DHVEVVL--TRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
               3430      3440      3450        

>>NP_006099 (OMIM: 604989) spondin-1 precursor [Homo sap  (807 aa)
 initn: 151 init1: 115 opt: 264  Z-score: 249.4  bits: 59.1 E(86068): 3.8e-07
Smith-Waterman score: 264; 31.2% identity (65.0% similar) in 160 aa overlap (40-192:44-197)

      10        20        30        40        50        60         
pF1KB4 TFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLHIAGNPTYYV
                                     :..  . .:  ..: . .::.. :.: .: 
NP_006 PALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYK
            20        30        40        50        60        70   

      70        80          90       100       110       120       
pF1KB4 PGQEYHVTISTS--TFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQFGNQFM--
       ::  :.::.:..  ..: :. . .:  .   .  .. .:.    : :.....  .:::  
NP_006 PGTSYRVTLSAAPPSYFRGFTLIALRENREGDKEEDHAGT----FQIIDEEE--TQFMSN
            80        90       100       110           120         

         130       140       150       160       170         180   
pF1KB4 CSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKD--ALAQQLCEQGAP
       : :.... .    : .. .::::::::::: . :. ...  . :.:  .:...:::: . 
NP_006 CPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDST
       130       140       150       160       170       180       

            190       200       210       220       230       240  
pF1KB4 TD-VTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAVTF
        : :: .: :                                                  
NP_006 FDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWE
       190       200       210       220       230       240       




3460 residues in 1 query   sequences
61265892 residues in 86068 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Feb  2 14:38:50 2017 done: Thu Feb  2 14:38:53 2017
 Total Scan time: 19.150 Total Display time:  0.620

Function used was FASTA [36.3.4 Apr, 2011]
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