Result of FASTA (omim) for pF1KE3275
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3275, 688 aa
  1>>>pF1KE3275     688 - 688 aa - 688 aa
Library: /omim/omim.rfq.tfa
  62246620 residues in 87639 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2145+/-0.000643; mu= 7.4369+/- 0.039
 mean_var=673.6523+/-156.248, 0's: 0 Z-trim(115.1): 1460  B-trim: 33 in 1/54
 Lambda= 0.049415
 statistics sampled from 23788 (25692) to 23788 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.293), width:  16
 Scan time: 10.470

The best scores are:                                      opt bits E(87639)
NP_005151 (OMIM: 109636) beta-adrenergic receptor  ( 688) 4673 350.2 1.5e-95
NP_001610 (OMIM: 109635) beta-adrenergic receptor  ( 689) 4042 305.3 5.3e-82
XP_011543075 (OMIM: 109635) PREDICTED: beta-adrene ( 659) 3825 289.7 2.4e-77
XP_011528277 (OMIM: 109636) PREDICTED: beta-adrene ( 523) 3603 273.7 1.3e-72
NP_001004105 (OMIM: 600869) G protein-coupled rece ( 560) 1128 97.3 1.7e-19
NP_001004106 (OMIM: 600869) G protein-coupled rece ( 576) 1128 97.4 1.7e-19
NP_002073 (OMIM: 600869) G protein-coupled recepto ( 589) 1128 97.4 1.7e-19
XP_006714922 (OMIM: 600869) PREDICTED: G protein-c ( 557) 1103 95.6 5.8e-19
XP_006714921 (OMIM: 600869) PREDICTED: G protein-c ( 559) 1103 95.6 5.8e-19
NP_005299 (OMIM: 600870) G protein-coupled recepto ( 590) 1081 94.0 1.8e-18
NP_892027 (OMIM: 137026) G protein-coupled recepto ( 578) 1077 93.7 2.1e-18
NP_001004057 (OMIM: 137026) G protein-coupled rece ( 532) 1068 93.0 3.2e-18
XP_005269765 (OMIM: 600870) PREDICTED: G protein-c ( 558) 1065 92.8 3.8e-18
NP_001004056 (OMIM: 137026) G protein-coupled rece ( 546) 1061 92.5 4.6e-18
NP_005298 (OMIM: 137026) G protein-coupled recepto ( 500) 1052 91.8 6.9e-18
XP_011532839 (OMIM: 600869) PREDICTED: G protein-c ( 550) 1050 91.8 7.9e-18
NP_002920 (OMIM: 180381,613411) rhodopsin kinase [ ( 563)  969 86.0 4.4e-16
NP_631948 (OMIM: 606987) rhodopsin kinase [Homo sa ( 553)  963 85.6 5.8e-16
XP_016861206 (OMIM: 606987) PREDICTED: rhodopsin k ( 553)  963 85.6 5.8e-16
XP_016863545 (OMIM: 137026) PREDICTED: G protein-c ( 440)  882 79.6 2.9e-14
XP_016863543 (OMIM: 137026) PREDICTED: G protein-c ( 486)  882 79.7   3e-14
XP_016863544 (OMIM: 137026) PREDICTED: G protein-c ( 454)  866 78.5 6.5e-14
NP_001337102 (OMIM: 137026) G protein-coupled rece ( 384)  845 76.8 1.7e-13
XP_016863546 (OMIM: 137026) PREDICTED: G protein-c ( 384)  845 76.8 1.7e-13
XP_016863547 (OMIM: 137026) PREDICTED: G protein-c ( 384)  845 76.8 1.7e-13
XP_016863549 (OMIM: 137026) PREDICTED: G protein-c ( 384)  845 76.8 1.7e-13
XP_016863548 (OMIM: 137026) PREDICTED: G protein-c ( 384)  845 76.8 1.7e-13
XP_016863552 (OMIM: 137026) PREDICTED: G protein-c ( 338)  836 76.1 2.5e-13
XP_011511751 (OMIM: 137026) PREDICTED: G protein-c ( 585)  836 76.6 3.2e-13
XP_016863541 (OMIM: 137026) PREDICTED: G protein-c ( 591)  836 76.6 3.2e-13
XP_011511750 (OMIM: 137026) PREDICTED: G protein-c ( 611)  836 76.6 3.2e-13
XP_011511749 (OMIM: 137026) PREDICTED: G protein-c ( 617)  836 76.6 3.2e-13
XP_011511752 (OMIM: 137026) PREDICTED: G protein-c ( 571)  827 75.9 4.9e-13
XP_016863551 (OMIM: 137026) PREDICTED: G protein-c ( 367)  808 74.2   1e-12
XP_016863550 (OMIM: 137026) PREDICTED: G protein-c ( 367)  808 74.2   1e-12
XP_006713943 (OMIM: 137026) PREDICTED: G protein-c ( 367)  808 74.2   1e-12
XP_005248019 (OMIM: 137026) PREDICTED: G protein-c ( 367)  808 74.2   1e-12
XP_011511755 (OMIM: 137026) PREDICTED: G protein-c ( 525)  765 71.4   1e-11
XP_005274634 (OMIM: 300075,300844,303600) PREDICTE ( 710)  763 71.5 1.3e-11
XP_006724570 (OMIM: 300075,300844,303600) PREDICTE ( 711)  763 71.5 1.3e-11
XP_016885208 (OMIM: 300075,300844,303600) PREDICTE ( 711)  763 71.5 1.3e-11
XP_005274630 (OMIM: 300075,300844,303600) PREDICTE ( 739)  763 71.6 1.3e-11
XP_016885207 (OMIM: 300075,300844,303600) PREDICTE ( 711)  755 71.0 1.9e-11
XP_016885202 (OMIM: 300075,300844,303600) PREDICTE ( 712)  755 71.0 1.9e-11
XP_016885206 (OMIM: 300075,300844,303600) PREDICTE ( 712)  755 71.0 1.9e-11
XP_016885203 (OMIM: 300075,300844,303600) PREDICTE ( 712)  755 71.0 1.9e-11
XP_011543865 (OMIM: 300075,300844,303600) PREDICTE ( 712)  755 71.0 1.9e-11
XP_016885205 (OMIM: 300075,300844,303600) PREDICTE ( 712)  755 71.0 1.9e-11
XP_016885204 (OMIM: 300075,300844,303600) PREDICTE ( 712)  755 71.0 1.9e-11
NP_004577 (OMIM: 300075,300844,303600) ribosomal p ( 740)  755 71.0 1.9e-11


>>NP_005151 (OMIM: 109636) beta-adrenergic receptor kina  (688 aa)
 initn: 4673 init1: 4673 opt: 4673  Z-score: 1836.5  bits: 350.2 E(87639): 1.5e-95
Smith-Waterman score: 4673; 100.0% identity (100.0% similar) in 688 aa overlap (1-688:1-688)

               10        20        30        40        50        60
pF1KE3 MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE3 DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE3 RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE3 LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR
              610       620       630       640       650       660

              670       680        
pF1KE3 APKFLNKPRSGTVELPKPSLCHRNSNGL
       ::::::::::::::::::::::::::::
NP_005 APKFLNKPRSGTVELPKPSLCHRNSNGL
              670       680        

>>NP_001610 (OMIM: 109635) beta-adrenergic receptor kina  (689 aa)
 initn: 4034 init1: 4034 opt: 4042  Z-score: 1593.3  bits: 305.3 E(87639): 5.3e-82
Smith-Waterman score: 4042; 84.0% identity (96.1% similar) in 689 aa overlap (1-688:1-689)

               10        20        30        40        50        60
pF1KE3 MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
       ::::::::::::::::::::::::::::::.:.:::::::::::::: .:.:.::.:::.
NP_001 MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
       ::.:.:::.:::::...:: : :.::::::.::::..::.:. :::.:.:.:::::::.:
NP_001 QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
       ::::::.:.::::.::.::::   ::::::::::..::::.::::.::::::::::::::
NP_001 SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
       :::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
       :::::::::::::::::.::::::::: ::::::::::::::::::::::: .:::::.:
NP_001 IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE
       ::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE
       :::::.::::::::::::::::::::::::::::::::::::::::::. :::::.::::
NP_001 VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA
       :.:::::::::::..:::: : :.:::::  ::...::: :.::::::::::::::::::
NP_001 LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE3 DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK
       :::::::::::::::::::: :::::.::::.:::::::::.:::....::.::..::::
NP_001 DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE3 RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL
       .:::::::::::::::::::::::: :.:::::::::::::::::::::::::::. :.:
NP_001 KAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE3 LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR
       ::::.: ::::::::..::.:..:.:::::.:::.::::.::::::: ....:::.:..:
NP_001 LTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQR
              610       620       630       640       650       660

              670       680         
pF1KE3 APKFLNKPRSGTVELPKPSLCHRNS-NGL
       .::. ::::: .::: :  : .:.: :::
NP_001 VPKMKNKPRSPVVELSKVPLVQRGSANGL
              670       680         

>>XP_011543075 (OMIM: 109635) PREDICTED: beta-adrenergic  (659 aa)
 initn: 3817 init1: 3817 opt: 3825  Z-score: 1509.9  bits: 289.7 E(87639): 2.4e-77
Smith-Waterman score: 3825; 83.4% identity (95.9% similar) in 652 aa overlap (38-688:8-659)

        10        20        30        40        50        60       
pF1KE3 LADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFNQKIGFLL
                                     :::::::::: .:.:.::.:::.::.:.::
XP_011                        MGKLKLQSIRSVMQKYLEDRGEVTFEKIFSQKLGYLL
                                      10        20        30       

        70        80        90       100       110       120       
pF1KE3 FKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSCSHPFSKQ
       :.:::::...:: : :.::::::.::::..::.:. :::.:.:.:::::::.:::::::.
XP_011 FRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKS
        40        50        60        70        80        90       

       130       140       150       160       170       180       
pF1KE3 AVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLT
       :.::::.::.::::   ::::::::::..::::.::::.:::::::::::::::::::::
XP_011 ATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLT
       100       110       120       130       140       150       

       190       200       210       220       230       240       
pF1KE3 MNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVS
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVS
       160       170       180       190       200       210       

       250       260       270       280       290       300       
pF1KE3 TGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEH
       ::::::::::.::::::::: ::::::::::::::::::::::: .:::::.::::::::
XP_011 TGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEH
       220       230       240       250       260       270       

       310       320       330       340       350       360       
pF1KE3 MHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTA
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::.:
XP_011 MHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVA
       280       290       300       310       320       330       

       370       380       390       400       410       420       
pF1KE3 YDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLLEG
       :::::::::::::::::::::::::::::::::::::::::. :::::.:::::.:::::
XP_011 YDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEG
       340       350       360       370       380       390       

       430       440       450       460       470       480       
pF1KE3 LLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGS
       ::::::..:::: : :.:::::  ::...::: :.:::::::::::::::::::::::::
XP_011 LLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGS
       400       410       420       430       440       450       

       490       500       510       520       530       540       
pF1KE3 FDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARKRAKNKQL
       ::::::::::::: :::::.::::.:::::::::.:::....::.::..::::.::::::
XP_011 FDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQL
       460       470       480       490       500       510       

       550       560       570       580       590       600       
pF1KE3 GHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQIL
       :::::::::::::::::: :.:::::::::::::::::::::::::::. :.:::::.: 
XP_011 GHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQ
       520       530       540       550       560       570       

       610       620       630       640       650       660       
pF1KE3 SVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRRAPKFLNK
       ::::::::..::.:..:.:::::.:::.::::.::::::: ....:::.:..:.::. ::
XP_011 SVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNK
       580       590       600       610       620       630       

       670       680         
pF1KE3 PRSGTVELPKPSLCHRNS-NGL
       ::: .::: :  : .:.: :::
XP_011 PRSPVVELSKVPLVQRGSANGL
       640       650         

>>XP_011528277 (OMIM: 109636) PREDICTED: beta-adrenergic  (523 aa)
 initn: 3603 init1: 3603 opt: 3603  Z-score: 1425.1  bits: 273.7 E(87639): 1.3e-72
Smith-Waterman score: 3603; 100.0% identity (100.0% similar) in 523 aa overlap (166-688:1-523)

         140       150       160       170       180       190     
pF1KE3 LSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLTMNEFSVHR
                                     ::::::::::::::::::::::::::::::
XP_011                               MESDKFTRFCQWKNVELNIHLTMNEFSVHR
                                             10        20        30

         200       210       220       230       240       250     
pF1KE3 IIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIV
               40        50        60        70        80        90

         260       270       280       290       300       310     
pF1KE3 CMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVY
              100       110       120       130       140       150

         320       330       340       350       360       370     
pF1KE3 RDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWF
              160       170       180       190       200       210

         380       390       400       410       420       430     
pF1KE3 SLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSK
              220       230       240       250       260       270

         440       450       460       470       480       490     
pF1KE3 RLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKG
              280       290       300       310       320       330

         500       510       520       530       540       550     
pF1KE3 IKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARKRAKNKQLGHEEDYAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARKRAKNKQLGHEEDYAL
              340       350       360       370       380       390

         560       570       580       590       600       610     
pF1KE3 GKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIK
              400       410       420       430       440       450

         620       630       640       650       660       670     
pF1KE3 DKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRRAPKFLNKPRSGTVEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRRAPKFLNKPRSGTVEL
              460       470       480       490       500       510

         680        
pF1KE3 PKPSLCHRNSNGL
       :::::::::::::
XP_011 PKPSLCHRNSNGL
              520   

>>NP_001004105 (OMIM: 600869) G protein-coupled receptor  (560 aa)
 initn: 861 init1: 341 opt: 1128  Z-score: 471.3  bits: 97.3 E(87639): 1.7e-19
Smith-Waterman score: 1128; 38.9% identity (64.7% similar) in 530 aa overlap (3-524:2-518)

               10        20        30         40         50        
pF1KE3 MADLEAVLADVSYLMAMEKSKATPAARASK-RIVLPEPSIRSVMQKYLA-ERNEITFDKI
         .:: ..:..  : : : . ..  ....: : .:  : : .  .  :. ::.  .. . 
NP_001  MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCE-
                10        20        30        40        50         

       60        70        80        90       100       110        
pF1KE3 FNQKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELL
         : :: :::..:: ..  :    : : . . :::   ... . : .::. . .. .   
NP_001 -RQPIGRLLFREFCATR-PELSRCVAFLDGVAEYEVTPDDKRKAC-GRQLTQNFLSHTGP
        60        70         80        90       100        110     

      120       130       140       150       160       170        
pF1KE3 SCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWK
       .      .: : .  ..: .    . :::   .   : :    :  ...:  :.:: :::
NP_001 DLIPEVPRQLVTNCTQRLEQGPC-KDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWK
         120       130        140       150       160       170    

      180       190       200       210       220       230        
pF1KE3 NVELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN
        .: .  .: : :  .:..:.:::::: .:.   :::::: : :.::::: ..::..:::
NP_001 WLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN
           180       190       200       210       220       230   

      240       250       260       270       280          290     
pF1KE3 ERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLH---YHLSQHGVFSEKEMR
       :. .:  :..    :.: ..::..: : ::..: :::::::.   ::..: : : : .  
NP_001 EKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG-FPEARAV
           240          250       260       270       280          

         300       310       320       330       340        350    
pF1KE3 FYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKP-HASVGTH
       :::.::  ::: .: . .::::::: :::::.::: ::::::::    . .  .. ::: 
NP_001 FYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTV
     290       300       310       320       330       340         

          360       370       380       390       400        410   
pF1KE3 GYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHE-IDRMTLTVNVEL
       :::::::. :.  :  : ::..:::.:.... :.:::.:.: : :.: ..:..  :  : 
NP_001 GYMAPEVV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEY
     350        360       370       380       390       400        

           420       430       440       450       460       470   
pF1KE3 PDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPP
        . :::. .::   :: .: ..::::.::...::::: .:: ......      ::. : 
NP_001 SERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPD
      410       420       430       440       450       460        

           480       490       500       510        520       530  
pF1KE3 RGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPL-VISERWQQEVTETVYEAVNAD
          .   :..:: .:.   .::..:   ::..:..:    .   ::.:..::        
NP_001 PQAIYCKDVLDIEQFS--TVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNV
      470       480         490       500       510       520      

            540       550       560       570       580       590  
pF1KE3 TDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRG
                                                                   
NP_001 FGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQR                          
        530       540       550       560                          

>>NP_001004106 (OMIM: 600869) G protein-coupled receptor  (576 aa)
 initn: 861 init1: 341 opt: 1128  Z-score: 471.2  bits: 97.4 E(87639): 1.7e-19
Smith-Waterman score: 1128; 38.9% identity (64.7% similar) in 530 aa overlap (3-524:2-518)

               10        20        30         40         50        
pF1KE3 MADLEAVLADVSYLMAMEKSKATPAARASK-RIVLPEPSIRSVMQKYLA-ERNEITFDKI
         .:: ..:..  : : : . ..  ....: : .:  : : .  .  :. ::.  .. . 
NP_001  MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCE-
                10        20        30        40        50         

       60        70        80        90       100       110        
pF1KE3 FNQKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELL
         : :: :::..:: ..  :    : : . . :::   ... . : .::. . .. .   
NP_001 -RQPIGRLLFREFCATR-PELSRCVAFLDGVAEYEVTPDDKRKAC-GRQLTQNFLSHTGP
        60        70         80        90       100        110     

      120       130       140       150       160       170        
pF1KE3 SCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWK
       .      .: : .  ..: .    . :::   .   : :    :  ...:  :.:: :::
NP_001 DLIPEVPRQLVTNCTQRLEQGPC-KDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWK
         120       130        140       150       160       170    

      180       190       200       210       220       230        
pF1KE3 NVELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN
        .: .  .: : :  .:..:.:::::: .:.   :::::: : :.::::: ..::..:::
NP_001 WLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN
           180       190       200       210       220       230   

      240       250       260       270       280          290     
pF1KE3 ERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLH---YHLSQHGVFSEKEMR
       :. .:  :..    :.: ..::..: : ::..: :::::::.   ::..: : : : .  
NP_001 EKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG-FPEARAV
           240          250       260       270       280          

         300       310       320       330       340        350    
pF1KE3 FYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKP-HASVGTH
       :::.::  ::: .: . .::::::: :::::.::: ::::::::    . .  .. ::: 
NP_001 FYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTV
     290       300       310       320       330       340         

          360       370       380       390       400        410   
pF1KE3 GYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHE-IDRMTLTVNVEL
       :::::::. :.  :  : ::..:::.:.... :.:::.:.: : :.: ..:..  :  : 
NP_001 GYMAPEVV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEY
     350        360       370       380       390       400        

           420       430       440       450       460       470   
pF1KE3 PDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPP
        . :::. .::   :: .: ..::::.::...::::: .:: ......      ::. : 
NP_001 SERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPD
      410       420       430       440       450       460        

           480       490       500       510        520       530  
pF1KE3 RGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPL-VISERWQQEVTETVYEAVNAD
          .   :..:: .:.   .::..:   ::..:..:    .   ::.:..::        
NP_001 PQAIYCKDVLDIEQFS--TVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNV
      470       480         490       500       510       520      

            540       550       560       570       580       590  
pF1KE3 TDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRG
                                                                   
NP_001 FGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL          
        530       540       550       560       570                

>>NP_002073 (OMIM: 600869) G protein-coupled receptor ki  (589 aa)
 initn: 861 init1: 341 opt: 1128  Z-score: 471.1  bits: 97.4 E(87639): 1.7e-19
Smith-Waterman score: 1128; 38.9% identity (64.7% similar) in 530 aa overlap (3-524:2-518)

               10        20        30         40         50        
pF1KE3 MADLEAVLADVSYLMAMEKSKATPAARASK-RIVLPEPSIRSVMQKYLA-ERNEITFDKI
         .:: ..:..  : : : . ..  ....: : .:  : : .  .  :. ::.  .. . 
NP_002  MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCE-
                10        20        30        40        50         

       60        70        80        90       100       110        
pF1KE3 FNQKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELL
         : :: :::..:: ..  :    : : . . :::   ... . : .::. . .. .   
NP_002 -RQPIGRLLFREFCATR-PELSRCVAFLDGVAEYEVTPDDKRKAC-GRQLTQNFLSHTGP
        60        70         80        90       100        110     

      120       130       140       150       160       170        
pF1KE3 SCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWK
       .      .: : .  ..: .    . :::   .   : :    :  ...:  :.:: :::
NP_002 DLIPEVPRQLVTNCTQRLEQGPC-KDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWK
         120       130        140       150       160       170    

      180       190       200       210       220       230        
pF1KE3 NVELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN
        .: .  .: : :  .:..:.:::::: .:.   :::::: : :.::::: ..::..:::
NP_002 WLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN
           180       190       200       210       220       230   

      240       250       260       270       280          290     
pF1KE3 ERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLH---YHLSQHGVFSEKEMR
       :. .:  :..    :.: ..::..: : ::..: :::::::.   ::..: : : : .  
NP_002 EKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAG-FPEARAV
           240          250       260       270       280          

         300       310       320       330       340        350    
pF1KE3 FYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKP-HASVGTH
       :::.::  ::: .: . .::::::: :::::.::: ::::::::    . .  .. ::: 
NP_002 FYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTV
     290       300       310       320       330       340         

          360       370       380       390       400        410   
pF1KE3 GYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHE-IDRMTLTVNVEL
       :::::::. :.  :  : ::..:::.:.... :.:::.:.: : :.: ..:..  :  : 
NP_002 GYMAPEVV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEY
     350        360       370       380       390       400        

           420       430       440       450       460       470   
pF1KE3 PDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPP
        . :::. .::   :: .: ..::::.::...::::: .:: ......      ::. : 
NP_002 SERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPD
      410       420       430       440       450       460        

           480       490       500       510        520       530  
pF1KE3 RGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPL-VISERWQQEVTETVYEAVNAD
          .   :..:: .:.   .::..:   ::..:..:    .   ::.:..::        
NP_002 PQAIYCKDVLDIEQFS--TVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNV
      470       480         490       500       510       520      

            540       550       560       570       580       590  
pF1KE3 TDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRG
                                                                   
NP_002 FGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTS
        530       540       550       560       570       580      

>>XP_006714922 (OMIM: 600869) PREDICTED: G protein-coupl  (557 aa)
 initn: 861 init1: 341 opt: 1103  Z-score: 461.7  bits: 95.6 E(87639): 5.8e-19
Smith-Waterman score: 1103; 40.9% identity (66.0% similar) in 470 aa overlap (61-524:28-486)

               40        50        60        70        80        90
pF1KE3 RIVLPEPSIRSVMQKYLAERNEITFDKIFNQKIGFLLFKDFCLNEINEAVPQVKFYEEIK
                                     : :: :::..:: ..  :    : : . . 
XP_006    MLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATR-PELSRCVAFLDGVA
                  10        20        30        40         50      

              100       110       120       130       140       150
pF1KE3 EYEKLDNEEDRLCRSRQIYDAYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYI
       :::   ... . : .::. . .. .   .      .: : .  ..: ..   . :::   
XP_006 EYEVTPDDKRKAC-GRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRL-EQGPCKDLFQELT
         60         70        80        90       100        110    

              160       170       180       190       200       210
pF1KE3 EEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLTMNEFSVHRIIGRGGFGEVYGCRK
       .   : :    :  ...:  :.:: ::: .: .  .: : :  .:..:.:::::: .:. 
XP_006 RLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV
          120       130       140        150       160       170   

              220       230       240       250       260       270
pF1KE3 ADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFI
         :::::: : :.::::: ..::..::::. .:  :..    :.: ..::..: : ::..
XP_006 RATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNS---RFVVSLAYAYETKDALCLV
           180       190       200       210          220       230

              280          290       300       310       320       
pF1KE3 LDLMNGGDLH---YHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDE
       : :::::::.   ::..: : : : .  :::.::  ::: .: . .::::::: :::::.
XP_006 LTLMNGGDLKFHIYHMGQAG-FPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDD
              240       250        260       270       280         

       330       340        350       360       370       380      
pF1KE3 HGHARISDLGLACDFSKKKP-HASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLR
       ::: ::::::::    . .  .. ::: :::::::. :.  :  : ::..:::.:.... 
XP_006 HGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVV-KNERYTFSPDWWALGCLLYEMIA
     290       300       310       320        330       340        

        390       400        410       420       430       440     
pF1KE3 GHSPFRQHKTKDKHE-IDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQ
       :.:::.:.: : :.: ..:..  :  :  . :::. .::   :: .: ..::::.::...
XP_006 GQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAR
      350       360       370       380       390       400        

         450       460       470       480       490       500     
pF1KE3 EVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQEL
       ::::: .:: ......      ::. :    .   :..:: .:.   .::..:   ::..
XP_006 EVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFS--TVKGVELEPTDQDF
      410       420       430       440       450         460      

         510        520       530       540       550       560    
pF1KE3 YKNFPL-VISERWQQEVTETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGKDCIMHGY
       :..:    .   ::.:..::                                        
XP_006 YQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSR
        470       480       490       500       510       520      

>>XP_006714921 (OMIM: 600869) PREDICTED: G protein-coupl  (559 aa)
 initn: 861 init1: 341 opt: 1103  Z-score: 461.6  bits: 95.6 E(87639): 5.8e-19
Smith-Waterman score: 1103; 40.9% identity (66.0% similar) in 470 aa overlap (61-524:30-488)

               40        50        60        70        80        90
pF1KE3 RIVLPEPSIRSVMQKYLAERNEITFDKIFNQKIGFLLFKDFCLNEINEAVPQVKFYEEIK
                                     : :: :::..:: ..  :    : : . . 
XP_006  MPHPCALGLWTQQLPSLPTERDYHSLCERQPIGRLLFREFCATR-PELSRCVAFLDGVA
                10        20        30        40         50        

              100       110       120       130       140       150
pF1KE3 EYEKLDNEEDRLCRSRQIYDAYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYI
       :::   ... . : .::. . .. .   .      .: : .  ..: ..   . :::   
XP_006 EYEVTPDDKRKAC-GRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRL-EQGPCKDLFQELT
       60        70         80        90       100        110      

              160       170       180       190       200       210
pF1KE3 EEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLTMNEFSVHRIIGRGGFGEVYGCRK
       .   : :    :  ...:  :.:: ::: .: .  .: : :  .:..:.:::::: .:. 
XP_006 RLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV
        120       130       140        150       160       170     

              220       230       240       250       260       270
pF1KE3 ADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFI
         :::::: : :.::::: ..::..::::. .:  :..    :.: ..::..: : ::..
XP_006 RATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNS---RFVVSLAYAYETKDALCLV
         180       190       200       210          220       230  

              280          290       300       310       320       
pF1KE3 LDLMNGGDLH---YHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDE
       : :::::::.   ::..: : : : .  :::.::  ::: .: . .::::::: :::::.
XP_006 LTLMNGGDLKFHIYHMGQAG-FPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDD
            240       250        260       270       280       290 

       330       340        350       360       370       380      
pF1KE3 HGHARISDLGLACDFSKKKP-HASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLR
       ::: ::::::::    . .  .. ::: :::::::. :.  :  : ::..:::.:.... 
XP_006 HGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVV-KNERYTFSPDWWALGCLLYEMIA
             300       310       320        330       340       350

        390       400        410       420       430       440     
pF1KE3 GHSPFRQHKTKDKHE-IDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQ
       :.:::.:.: : :.: ..:..  :  :  . :::. .::   :: .: ..::::.::...
XP_006 GQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAR
              360       370       380       390       400       410

         450       460       470       480       490       500     
pF1KE3 EVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQEL
       ::::: .:: ......      ::. :    .   :..:: .:.   .::..:   ::..
XP_006 EVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFS--TVKGVELEPTDQDF
              420       430       440       450         460        

         510        520       530       540       550       560    
pF1KE3 YKNFPL-VISERWQQEVTETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGKDCIMHGY
       :..:    .   ::.:..::                                        
XP_006 YQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSR
      470       480       490       500       510       520        

>>NP_005299 (OMIM: 600870) G protein-coupled receptor ki  (590 aa)
 initn: 817 init1: 306 opt: 1081  Z-score: 453.0  bits: 94.0 E(87639): 1.8e-18
Smith-Waterman score: 1081; 37.6% identity (66.2% similar) in 532 aa overlap (3-524:2-518)

               10        20        30         40         50        
pF1KE3 MADLEAVLADVSYLMAMEKSKATPAARASK-RIVLPEPSIRSVMQ-KYLAERNEITF-DK
         .:: ..:..  : : : . .   ....: . .:  : : .  . .   .:.  .. ::
NP_005  MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDK
                10        20        30        40        50         

        60        70        80         90       100       110      
pF1KE3 IFNQKIGFLLFKDFCLNEINEAVP-QVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKE
          : :: :::..::  :   ..   ..: . . ::: .  .:    ....:.  :.  .
NP_005 ---QPIGRLLFRQFC--ETRPGLECYIQFLDSVAEYE-VTPDEKLGEKGKEIMTKYLTPK
         60        70          80        90        100       110   

        120       130       140       150       160       170      
pF1KE3 LLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQ
               ... : ... .: .:   . ::.   . . : :::. :.....:  : :: :
NP_005 SPVFIAQVGQDLVSQTEEKLLQKPC-KELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQ
           120       130        140       150       160       170  

        180       190       200       210       220       230      
pF1KE3 WKNVELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLA
       :: .: .  .: : :  .:..:.:::::: .:.   :::::: : :.::::: ..::..:
NP_005 WKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMA
             180       190       200       210       220       230 

        240       250       260       270       280         290    
pF1KE3 LNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGV--FSEKEM
       :::. .:  :..    :.: ..::..: : ::..: .::::::..:. . :   : :.. 
NP_005 LNEKQILEKVNS---QFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERA
             240          250       260       270       280        

          300       310       320       330       340        350   
pF1KE3 RFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKK-PHASVGT
        :::.::. ::: .: . .::::::: :::::..:: ::::::::  . .    .. :::
NP_005 LFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGT
      290       300       310       320       330       340        

           360       370       380       390       400        410  
pF1KE3 HGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHE-IDRMTLTVNVE
        ::::::::..   :  : :...:::.......:.:::: .: : :.: .:: .: ..  
NP_005 VGYMAPEVLNNQR-YGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEV
      350       360        370       380       390       400       

            420       430       440       450       460       470  
pF1KE3 LPDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIP
           :: : ::. . :: .:...::::.  :. :::.: ::........      ::..:
NP_005 YSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVP
       410       420       430       440       450       460       

             480       490       500       510        520       530
pF1KE3 -PRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPL-VISERWQQEVTETVYEAVN
        ::. :   :..:: .:.   .::..:   :...:..:    .:  ::.:. ::      
NP_005 DPRA-VYCKDVLDIEQFS--TVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKEL
       470        480         490       500       510       520    

              540       550       560       570       580       590
pF1KE3 ADTDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEW
                                                                   
NP_005 NVFGPNGTLPPDLNRNHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSS
          530       540       550       560       570       580    




688 residues in 1 query   sequences
62246620 residues in 87639 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Jul 27 10:33:17 2017 done: Thu Jul 27 10:33:19 2017
 Total Scan time: 10.470 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
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