Result of FASTA (omim) for pF1KE2370
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2370, 173 aa
  1>>>pF1KE2370 173 - 173 aa - 173 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9557+/-0.000314; mu= 14.6546+/- 0.020
 mean_var=60.9296+/-12.386, 0's: 0 Z-trim(115.6): 16  B-trim: 0 in 0/49
 Lambda= 0.164309
 statistics sampled from 26114 (26130) to 26114 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.306), width:  16
 Scan time:  5.560

The best scores are:                                      opt bits E(85289)
NP_000385 (OMIM: 123580,604219) alpha-crystallin A ( 173) 1178 287.1 9.4e-78
XP_005261150 (OMIM: 123580,604219) PREDICTED: alph ( 136)  745 184.4 6.1e-47
NP_001276736 (OMIM: 123590,608810,613763,613869,61 ( 175)  657 163.6 1.4e-40
XP_011540910 (OMIM: 123590,608810,613763,613869,61 ( 175)  657 163.6 1.4e-40
NP_001876 (OMIM: 123590,608810,613763,613869,61518 ( 175)  657 163.6 1.4e-40
NP_001276737 (OMIM: 123590,608810,613763,613869,61 ( 175)  657 163.6 1.4e-40
NP_653218 (OMIM: 610695) heat shock protein beta-6 ( 160)  437 111.4 6.7e-25
NP_001317308 (OMIM: 123590,608810,613763,613869,61 ( 108)  431 109.9 1.3e-24
NP_001531 (OMIM: 602195,606595,608634) heat shock  ( 205)  360 93.3 2.5e-19
NP_001532 (OMIM: 602179) heat shock protein beta-2 ( 182)  324 84.7 8.6e-17
NP_006299 (OMIM: 604624,613376) heat shock protein ( 150)  216 59.0 3.7e-09
NP_055180 (OMIM: 158590,608014,608673) heat shock  ( 196)  215 58.9 5.5e-09
XP_011539551 (OMIM: 610692) PREDICTED: heat shock  ( 263)  162 46.4 4.2e-05
NP_149971 (OMIM: 608344) heat shock protein beta-9 ( 159)  156 44.8 7.5e-05
XP_011539552 (OMIM: 610692) PREDICTED: heat shock  ( 262)  152 44.0 0.00022
NP_055239 (OMIM: 610692) heat shock protein beta-7 ( 170)  149 43.2 0.00025


>>NP_000385 (OMIM: 123580,604219) alpha-crystallin A cha  (173 aa)
 initn: 1178 init1: 1178 opt: 1178  Z-score: 1516.9  bits: 287.1 E(85289): 9.4e-78
Smith-Waterman score: 1178; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)

               10        20        30        40        50        60
pF1KE2 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
               70        80        90       100       110       120

              130       140       150       160       170   
pF1KE2 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
              130       140       150       160       170   

>>XP_005261150 (OMIM: 123580,604219) PREDICTED: alpha-cr  (136 aa)
 initn: 745 init1: 745 opt: 745  Z-score: 963.7  bits: 184.4 E(85289): 6.1e-47
Smith-Waterman score: 745; 99.1% identity (100.0% similar) in 111 aa overlap (63-173:26-136)

             40        50        60        70        80        90  
pF1KE2 EYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDD
                                     .:::::::::::::::::::::::::::::
XP_005      MPVCPGDSHRPPKALPHLVCGRRGRQVRSDRDKFVIFLDVKHFSPEDLTVKVQDD
                    10        20        30        40        50     

            100       110       120       130       140       150  
pF1KE2 FVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDA
          60        70        80        90       100       110     

            160       170   
pF1KE2 THAERAIPVSREEKPTSAPSS
       :::::::::::::::::::::
XP_005 THAERAIPVSREEKPTSAPSS
         120       130      

>>NP_001276736 (OMIM: 123590,608810,613763,613869,615184  (175 aa)
 initn: 504 init1: 406 opt: 657  Z-score: 849.3  bits: 163.6 E(85289): 1.4e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)

               10         20        30        40        50         
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
       ::..:.:::..: . ::. ::::::::::: :.: ::.:  :...::.: .  :..:  .
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
               10        20        30         40        50         

          60        70        80        90       100       110     
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
        .:.:.::.: ..:.: . :::::::::.: :::  : .:.::::.::::.::.::::::
NP_001 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
      60        70        80        90       100       110         

         120       130       140       150       160         170   
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
       :.::.:..::  ... :::.::.::  ::. :.    .  ::.::..:::::  :.::  
NP_001 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
     120       130       140       150           160       170     

>>XP_011540910 (OMIM: 123590,608810,613763,613869,615184  (175 aa)
 initn: 504 init1: 406 opt: 657  Z-score: 849.3  bits: 163.6 E(85289): 1.4e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)

               10         20        30        40        50         
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
       ::..:.:::..: . ::. ::::::::::: :.: ::.:  :...::.: .  :..:  .
XP_011 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
               10        20        30         40        50         

          60        70        80        90       100       110     
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
        .:.:.::.: ..:.: . :::::::::.: :::  : .:.::::.::::.::.::::::
XP_011 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
      60        70        80        90       100       110         

         120       130       140       150       160         170   
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
       :.::.:..::  ... :::.::.::  ::. :.    .  ::.::..:::::  :.::  
XP_011 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
     120       130       140       150           160       170     

>>NP_001876 (OMIM: 123590,608810,613763,613869,615184) a  (175 aa)
 initn: 504 init1: 406 opt: 657  Z-score: 849.3  bits: 163.6 E(85289): 1.4e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)

               10         20        30        40        50         
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
       ::..:.:::..: . ::. ::::::::::: :.: ::.:  :...::.: .  :..:  .
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
               10        20        30         40        50         

          60        70        80        90       100       110     
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
        .:.:.::.: ..:.: . :::::::::.: :::  : .:.::::.::::.::.::::::
NP_001 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
      60        70        80        90       100       110         

         120       130       140       150       160         170   
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
       :.::.:..::  ... :::.::.::  ::. :.    .  ::.::..:::::  :.::  
NP_001 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
     120       130       140       150           160       170     

>>NP_001276737 (OMIM: 123590,608810,613763,613869,615184  (175 aa)
 initn: 504 init1: 406 opt: 657  Z-score: 849.3  bits: 163.6 E(85289): 1.4e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)

               10         20        30        40        50         
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
       ::..:.:::..: . ::. ::::::::::: :.: ::.:  :...::.: .  :..:  .
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
               10        20        30         40        50         

          60        70        80        90       100       110     
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
        .:.:.::.: ..:.: . :::::::::.: :::  : .:.::::.::::.::.::::::
NP_001 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
      60        70        80        90       100       110         

         120       130       140       150       160         170   
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
       :.::.:..::  ... :::.::.::  ::. :.    .  ::.::..:::::  :.::  
NP_001 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
     120       130       140       150           160       170     

>>NP_653218 (OMIM: 610695) heat shock protein beta-6 [Ho  (160 aa)
 initn: 395 init1: 289 opt: 437  Z-score: 568.1  bits: 111.4 E(85289): 6.7e-25
Smith-Waterman score: 437; 44.4% identity (73.6% similar) in 144 aa overlap (1-140:3-143)

                 10            20        30        40        50    
pF1KE2   MDVTIQHPWFKRTLGPF----YPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFR
         . : .:  :..:. .:.     :.::::: :::::.: .:  .  .:..:::   :  
NP_653 MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYY---LRA
               10        20        30        40        50          

           60        70        80        90       100       110    
pF1KE2 TVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREF
         .   ...: .:  .: ..:::::::::...:::  . ::.:..:.:: :.::...:::
NP_653 PSVALPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREF
        60        70        80        90       100       110       

          120       130       140       150       160       170   
pF1KE2 HRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
       ::::::: .:: .:.. .:: .:.:.                                 
NP_653 HRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK                
       120       130       140       150       160                

>>NP_001317308 (OMIM: 123590,608810,613763,613869,615184  (108 aa)
 initn: 402 init1: 347 opt: 431  Z-score: 562.9  bits: 109.9 E(85289): 1.3e-24
Smith-Waterman score: 431; 56.4% identity (80.9% similar) in 110 aa overlap (64-171:1-106)

            40        50        60        70        80        90   
pF1KE2 YDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDF
                                     .: ..:.: . :::::::::.: :::  : 
NP_001                               MRLEKDRFSVNLDVKHFSPEELKVKVLGDV
                                             10        20        30

           100       110       120       130       140       150   
pF1KE2 VEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDAT
       .:.::::.::::.::.:::::::.::.:..::  ... :::.::.::  ::. :.    .
NP_001 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----S
               40        50        60        70        80          

           160         170   
pF1KE2 HAERAIPVSREEKP--TSAPSS
         ::.::..:::::  :.::  
NP_001 GPERTIPITREEKPAVTAAPKK
         90       100        

>>NP_001531 (OMIM: 602195,606595,608634) heat shock prot  (205 aa)
 initn: 382 init1: 327 opt: 360  Z-score: 467.9  bits: 93.3 E(85289): 2.5e-19
Smith-Waterman score: 364; 41.4% identity (60.9% similar) in 174 aa overlap (16-166:18-188)

                 10            20        30        40              
pF1KE2   MDVTIQHPWFKRTLGPF---YP-SRLFDQFFGEGLFEYDLLPFLSST-----------
                        ::   :: :::::: ::   .  .   .:...           
NP_001 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
               10        20        30        40        50        60

                    50        60        70        80        90     
pF1KE2 --------ISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVE
                .: : ..: :  :.::.::.:   :.. . :::.::.:..::::..:  ::
NP_001 AAIESPAVAAPAYSRALSRQ-LSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVE
               70        80         90       100       110         

         100       110       120       130       140       150     
pF1KE2 IHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHA
       : :::.::::.:::::: : :.: :: .:: . .: ::: .: ::  .:  .  : .   
NP_001 ITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK--LATQSN
     120       130       140       150       160       170         

         160       170             
pF1KE2 ERAIPVSREEKPTSAPSS          
       : .:::. : .                 
NP_001 EITIPVTFESRAQLGGPEAAKSDETAAK
       180       190       200     

>>NP_001532 (OMIM: 602179) heat shock protein beta-2 [Ho  (182 aa)
 initn: 336 init1: 279 opt: 324  Z-score: 422.5  bits: 84.7 E(85289): 8.6e-17
Smith-Waterman score: 324; 38.0% identity (62.0% similar) in 158 aa overlap (19-170:21-178)

                 10        20        30         40        50       
pF1KE2   MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLL-PFLSSTISPYYRQSLFRTVL
                           :::: .: :::::.  ..: : :        : .      
NP_001 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGS
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KE2 DSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRR
        .: ::.: .. ::  ::::.::.:...::.. :...:. ..: .: : ::..:::: : 
NP_001 RAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRT
               70        80        90       100       110       120

       120       130       140       150            160       170  
pF1KE2 YRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAI-----PVSREEKPTSAPS
       : ::..::   .  .:: ::.:.. .:.    ::.   :  :     : . ::.  .:  
NP_001 YVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIV
              130       140       150       160       170       180

         
pF1KE2 S 
         
NP_001 EP
         




173 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 12:58:05 2016 done: Sun Nov  6 12:58:06 2016
 Total Scan time:  5.560 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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