Result of FASTA (omim) for pF1KE2534
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2534, 344 aa
  1>>>pF1KE2534 344 - 344 aa - 344 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1639+/-0.000449; mu= 7.4224+/- 0.028
 mean_var=232.0490+/-48.822, 0's: 0 Z-trim(116.4): 298  B-trim: 706 in 1/55
 Lambda= 0.084195
 statistics sampled from 27077 (27529) to 27077 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.323), width:  16
 Scan time:  7.000

The best scores are:                                      opt bits E(85289)
NP_002474 (OMIM: 163980) carcinoembryonic antigen- ( 344) 2288 291.2 2.1e-78
XP_011525292 (OMIM: 163980) PREDICTED: carcinoembr ( 324) 2147 274.1 2.9e-73
NP_001171745 (OMIM: 109770) carcinoembryonic antig ( 368) 1867 240.2 5.5e-63
NP_001171742 (OMIM: 109770) carcinoembryonic antig ( 430) 1867 240.2   6e-63
XP_005258470 (OMIM: 114890) PREDICTED: carcinoembr ( 524) 1833 236.2 1.2e-61
NP_001020083 (OMIM: 109770) carcinoembryonic antig ( 464) 1832 236.0 1.2e-61
XP_011525508 (OMIM: 109770) PREDICTED: carcinoembr ( 351) 1830 235.6 1.2e-61
NP_001192273 (OMIM: 109770) carcinoembryonic antig ( 468) 1832 236.0 1.2e-61
NP_001703 (OMIM: 109770) carcinoembryonic antigen- ( 526) 1832 236.1 1.3e-61
NP_004354 (OMIM: 114890) carcinoembryonic antigen- ( 702) 1833 236.4 1.4e-61
NP_001278413 (OMIM: 114890) carcinoembryonic antig ( 702) 1833 236.4 1.4e-61
NP_001295327 (OMIM: 114890) carcinoembryonic antig ( 701) 1827 235.7 2.4e-61
XP_016881634 (OMIM: 114890) PREDICTED: carcinoembr ( 701) 1827 235.7 2.4e-61
NP_001171744 (OMIM: 109770) carcinoembryonic antig ( 461) 1820 234.6 3.3e-61
NP_001807 (OMIM: 615747) carcinoembryonic antigen- ( 349) 1792 231.0 2.9e-60
XP_016881684 (OMIM: 615747) PREDICTED: carcinoembr ( 349) 1792 231.0 2.9e-60
XP_011524624 (OMIM: 114890) PREDICTED: carcinoembr ( 524) 1745 225.5   2e-58
XP_016881685 (OMIM: 615747) PREDICTED: carcinoembr ( 331) 1707 220.7 3.7e-57
XP_016881683 (OMIM: 615747) PREDICTED: carcinoembr ( 368) 1707 220.7 3.9e-57
XP_011524642 (OMIM: 615747) PREDICTED: carcinoembr ( 415) 1707 220.8 4.2e-57
XP_016881635 (OMIM: 114890) PREDICTED: carcinoembr ( 617) 1371 180.2   1e-44
XP_011524644 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 1278 168.4 1.5e-41
XP_016881687 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 1278 168.4 1.5e-41
XP_011524643 (OMIM: 615747) PREDICTED: carcinoembr ( 255) 1278 168.4 1.5e-41
NP_112536 (OMIM: 176391) pregnancy-specific beta-1 ( 335) 1257 166.0   1e-40
NP_001288637 (OMIM: 176398) pregnancy-specific bet ( 333) 1253 165.5 1.5e-40
XP_005259132 (OMIM: 176398) PREDICTED: pregnancy-s ( 402) 1254 165.7 1.5e-40
XP_011525288 (OMIM: 176397) PREDICTED: pregnancy-s ( 326) 1246 164.7 2.6e-40
XP_016882492 (OMIM: 176394) PREDICTED: pregnancy-s ( 335) 1237 163.6 5.7e-40
NP_002772 (OMIM: 176394) pregnancy-specific beta-1 ( 335) 1237 163.6 5.7e-40
NP_001123486 (OMIM: 176394) pregnancy-specific bet ( 335) 1237 163.6 5.7e-40
XP_011525428 (OMIM: 176392) PREDICTED: pregnancy-s ( 357) 1226 162.3 1.5e-39
XP_016882490 (OMIM: 176393) PREDICTED: pregnancy-s ( 333) 1224 162.0 1.7e-39
XP_016882491 (OMIM: 176393) PREDICTED: pregnancy-s ( 333) 1223 161.9 1.8e-39
NP_001288636 (OMIM: 176398) pregnancy-specific bet ( 333) 1222 161.7   2e-39
XP_016882494 (OMIM: 176398) PREDICTED: pregnancy-s ( 402) 1223 162.0 2.1e-39
NP_002776 (OMIM: 176401) pregnancy-specific beta-1 ( 335) 1221 161.6 2.2e-39
NP_001263424 (OMIM: 176393) pregnancy-specific bet ( 326) 1214 160.8 3.9e-39
NP_998798 (OMIM: 176393) pregnancy-specific beta-1 ( 326) 1213 160.6 4.2e-39
XP_011525427 (OMIM: 176390) PREDICTED: pregnancy-s ( 333) 1202 159.3 1.1e-38
XP_005259122 (OMIM: 176390) PREDICTED: pregnancy-s ( 333) 1200 159.1 1.3e-38
NP_001317453 (OMIM: 176390) pregnancy-specific bet ( 326) 1192 158.1 2.5e-38
XP_016882487 (OMIM: 176393) PREDICTED: pregnancy-s ( 349) 1131 150.7 4.4e-36
XP_016882488 (OMIM: 176393) PREDICTED: pregnancy-s ( 349) 1130 150.6 4.7e-36
XP_016882489 (OMIM: 176393) PREDICTED: pregnancy-s ( 342) 1120 149.4 1.1e-35
XP_016881686 (OMIM: 615747) PREDICTED: carcinoembr ( 295) 1004 135.2 1.7e-31
XP_011525429 (OMIM: 176392) PREDICTED: pregnancy-s ( 272)  906 123.2 6.3e-28
NP_001264092 (OMIM: 609142) carcinoembryonic antig ( 212)  809 111.3 1.9e-24
NP_001806 (OMIM: 609142) carcinoembryonic antigen- ( 252)  809 111.4 2.1e-24
NP_001027020 (OMIM: 176395) pregnancy-specific bet ( 424)  730 102.1 2.3e-21


>>NP_002474 (OMIM: 163980) carcinoembryonic antigen-rela  (344 aa)
 initn: 2288 init1: 2288 opt: 2288  Z-score: 1528.5  bits: 291.2 E(85289): 2.1e-78
Smith-Waterman score: 2288; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
              250       260       270       280       290       300

              310       320       330       340    
pF1KE2 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI
       ::::::::::::::::::::::::::::::::::::::::::::
NP_002 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI
              310       320       330       340    

>>XP_011525292 (OMIM: 163980) PREDICTED: carcinoembryoni  (324 aa)
 initn: 2147 init1: 2147 opt: 2147  Z-score: 1436.2  bits: 274.1 E(85289): 2.9e-73
Smith-Waterman score: 2147; 100.0% identity (100.0% similar) in 319 aa overlap (1-319:1-319)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
              250       260       270       280       290       300

              310       320       330       340    
pF1KE2 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI
       :::::::::::::::::::                         
XP_011 AHNSATGLNRTTVTMITVSDWTRP                    
              310       320                        

>>NP_001171745 (OMIM: 109770) carcinoembryonic antigen-r  (368 aa)
 initn: 1929 init1: 1825 opt: 1867  Z-score: 1251.8  bits: 240.2 E(85289): 5.5e-63
Smith-Waterman score: 1867; 82.5% identity (90.5% similar) in 348 aa overlap (1-344:1-348)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       ::  :::  :..:::. .::::::::::::::::.:: :: :::::::::::::.:::::
NP_001 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       . .:::::::::::::  ::::.::::::::::: :::::::::::::::::::::::::
NP_001 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:.::::::.
NP_001 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       :.::::::::::::::: ::::::: :::.: ::::::::.:::::::::::: ::::.:
NP_001 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       ::::: . :::: ::.:::.:::::::::::.::::::::::::::::::::::::: :.
NP_001 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH
              250       260       270       280       290       300

              310       320           330       340                
pF1KE2 AHNSATGLNRTTVTMITVSGSA-PV---LSAVATVGITIGVLARVALI            
       :.::.:: :::::  : :. .: :    ::  : .::.:::.: ::::            
NP_001 ANNSVTGCNRTTVKTIIVTDNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGK
              310       320       330       340       350       360

NP_001 TGSSGPLQ
               

>>NP_001171742 (OMIM: 109770) carcinoembryonic antigen-r  (430 aa)
 initn: 1929 init1: 1825 opt: 1867  Z-score: 1251.0  bits: 240.2 E(85289): 6e-63
Smith-Waterman score: 1867; 82.5% identity (90.5% similar) in 348 aa overlap (1-344:1-348)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       ::  :::  :..:::. .::::::::::::::::.:: :: :::::::::::::.:::::
NP_001 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       . .:::::::::::::  ::::.::::::::::: :::::::::::::::::::::::::
NP_001 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:.::::::.
NP_001 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       :.::::::::::::::: ::::::: :::.: ::::::::.:::::::::::: ::::.:
NP_001 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       ::::: . :::: ::.:::.:::::::::::.::::::::::::::::::::::::: :.
NP_001 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH
              250       260       270       280       290       300

              310       320           330       340                
pF1KE2 AHNSATGLNRTTVTMITVSGSA-PV---LSAVATVGITIGVLARVALI            
       :.::.:: :::::  : :. .: :    ::  : .::.:::.: ::::            
NP_001 ANNSVTGCNRTTVKTIIVTDNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGK
              310       320       330       340       350       360

NP_001 TGRASDQRDLTEHKPSVSNHTQDHSNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTAT
              370       380       390       400       410       420

>>XP_005258470 (OMIM: 114890) PREDICTED: carcinoembryoni  (524 aa)
 initn: 1833 init1: 1833 opt: 1833  Z-score: 1227.8  bits: 236.2 E(85289): 1.2e-61
Smith-Waterman score: 1833; 83.9% identity (92.6% similar) in 323 aa overlap (1-323:1-323)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       :  ::::: :  .::...::::::::::::::::::::::::::::::::::::.:::::
XP_005 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       . .:::::::::::::  :.::::::::::::::::::: :::::::::::. :::::::
XP_005 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::.:::::::::::::::.:::::::::::::::.:::::::::::::::.:..::::::
XP_005 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       :.::::::::::::::: ::::..: :::..::.:: :::.:: ::: : ::::::::.:
XP_005 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       :::: ...:: :::::::::::::::::::::.:::::::::::::::::::::::: ::
XP_005 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ
              250       260       270       280       290       300

              310       320       330       340                    
pF1KE2 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI                
       :::: ::::::::: ::: .  :                                     
XP_005 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN
              310       320       330       340       350       360

>--
 initn: 931 init1: 896 opt: 972  Z-score: 662.6  bits: 131.6 E(85289): 3.6e-30
Smith-Waterman score: 972; 75.6% identity (86.6% similar) in 201 aa overlap (146-344:324-524)

         120       130       140       150       160       170     
pF1KE2 DTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTT
                                     :: :.:::::::::.::::.:::::.::::
XP_005 SGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTT
           300       310       320       330       340       350   

         180       190       200       210       220       230     
pF1KE2 YLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLY
       ::::::.::::::::::::: : ::::::: :::.: ::: :::  :...:::: :::::
XP_005 YLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLY
           360       370       380       390       400       410   

         240       250       260       270       280       290     
pF1KE2 GPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSG
       ::: :::::: . :::: ::.:::::::::::::::.:.:..:: :::::: ::: .:::
XP_005 GPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSG
           420       430       440       450       460       470   

         300       310         320       330       340    
pF1KE2 SYMCQAHNSATGLNRTTVTMITVS--GSAPVLSAVATVGITIGVLARVALI
        : :::.:::.: .::::  ::::  :..: ::: ::::: ::::. ::::
XP_005 LYTCQANNSASGHSRTTVKTITVSASGTSPGLSAGATVGIMIGVLVGVALI
           480       490       500       510       520    

>>NP_001020083 (OMIM: 109770) carcinoembryonic antigen-r  (464 aa)
 initn: 1936 init1: 1832 opt: 1832  Z-score: 1227.7  bits: 236.0 E(85289): 1.2e-61
Smith-Waterman score: 1832; 84.0% identity (92.3% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       ::  :::  :..:::. .::::::::::::::::.:: :: :::::::::::::.:::::
NP_001 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       . .:::::::::::::  ::::.::::::::::: :::::::::::::::::::::::::
NP_001 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:.::::::.
NP_001 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       :.::::::::::::::: ::::::: :::.: ::::::::.:::::::::::: ::::.:
NP_001 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       ::::: . :::: ::.:::.:::::::::::.::::::::::::::::::::::::: :.
NP_001 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH
              250       260       270       280       290       300

              310       320       330       340                    
pF1KE2 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI                
       :.::.:: :::::  : :.  .::..                                  
NP_001 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF
              310       320       330       340       350       360

>--
 initn: 385 init1: 284 opt: 290  Z-score: 215.4  bits: 48.7 E(85289): 2.9e-05
Smith-Waterman score: 290; 44.6% identity (73.3% similar) in 101 aa overlap (146-244:327-427)

         120       130       140       150       160       170     
pF1KE2 DTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTT
                                     ::.:...... . :::.: .::  .  . .
NP_001 YTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGIS
        300       310       320       330       340       350      

         180       190       200       210       220       230     
pF1KE2 YLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLY
         :. ..:::: : :..::.:: ::..  :::.:::.: ::. :: : :.:::. ::: :
NP_001 IRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY
        360       370       380       390       400       410      

           240       250       260       270       280       290   
pF1KE2 G--PDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNN
       .  :.   .::                                                 
NP_001 NALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGSSGPLQ            
        420       430       440       450       460                

>>XP_011525508 (OMIM: 109770) PREDICTED: carcinoembryoni  (351 aa)
 initn: 1877 init1: 1822 opt: 1830  Z-score: 1227.7  bits: 235.6 E(85289): 1.2e-61
Smith-Waterman score: 1830; 84.9% identity (92.3% similar) in 325 aa overlap (1-325:1-324)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       ::  :::  :..:::. .::::::::::::::::.:: :: :::::::::::::.:::::
XP_011 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       . .:::::::::::::  ::::.::::::::::: :::::::::::::::::::::::::
XP_011 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:.::::::.
XP_011 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       :.::::::::::::::: ::::::: :::.: ::::::::.:::::::::::: ::::.:
XP_011 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       ::::: . :::: ::.:::.:::::::::::.::::::::::::::::::::::::: :.
XP_011 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH
              250       260       270       280       290       300

              310       320       330       340            
pF1KE2 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI        
       :.::.:: :::::  : :. : :::                           
XP_011 ANNSVTGCNRTTVKTIIVTES-PVLGEDEAVPGQHHPQHKPCQEGGCWDVLV
              310       320        330       340       350 

>>NP_001192273 (OMIM: 109770) carcinoembryonic antigen-r  (468 aa)
 initn: 1936 init1: 1832 opt: 1832  Z-score: 1227.7  bits: 236.0 E(85289): 1.2e-61
Smith-Waterman score: 1832; 84.0% identity (92.3% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       ::  :::  :..:::. .::::::::::::::::.:: :: :::::::::::::.:::::
NP_001 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       . .:::::::::::::  ::::.::::::::::: :::::::::::::::::::::::::
NP_001 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:.::::::.
NP_001 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       :.::::::::::::::: ::::::: :::.: ::::::::.:::::::::::: ::::.:
NP_001 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       ::::: . :::: ::.:::.:::::::::::.::::::::::::::::::::::::: :.
NP_001 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH
              250       260       270       280       290       300

              310       320       330       340                    
pF1KE2 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI                
       :.::.:: :::::  : :.  .::..                                  
NP_001 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF
              310       320       330       340       350       360

>--
 initn: 385 init1: 284 opt: 290  Z-score: 215.4  bits: 48.7 E(85289): 2.9e-05
Smith-Waterman score: 290; 44.6% identity (73.3% similar) in 101 aa overlap (146-244:327-427)

         120       130       140       150       160       170     
pF1KE2 DTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTT
                                     ::.:...... . :::.: .::  .  . .
NP_001 YTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGIS
        300       310       320       330       340       350      

         180       190       200       210       220       230     
pF1KE2 YLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLY
         :. ..:::: : :..::.:: ::..  :::.:::.: ::. :: : :.:::. ::: :
NP_001 IRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY
        360       370       380       390       400       410      

           240       250       260       270       280       290   
pF1KE2 G--PDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNN
       .  :.   .::                                                 
NP_001 NALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRTTPMTHLTR        
        420       430       440       450       460                

>>NP_001703 (OMIM: 109770) carcinoembryonic antigen-rela  (526 aa)
 initn: 1936 init1: 1832 opt: 1832  Z-score: 1227.1  bits: 236.1 E(85289): 1.3e-61
Smith-Waterman score: 1832; 84.0% identity (92.3% similar) in 326 aa overlap (1-326:1-326)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       ::  :::  :..:::. .::::::::::::::::.:: :: :::::::::::::.:::::
NP_001 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       . .:::::::::::::  ::::.::::::::::: :::::::::::::::::::::::::
NP_001 QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::.:.::::::.
NP_001 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       :.::::::::::::::: ::::::: :::.: ::::::::.:::::::::::: ::::.:
NP_001 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       ::::: . :::: ::.:::.:::::::::::.::::::::::::::::::::::::: :.
NP_001 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH
              250       260       270       280       290       300

              310       320       330       340                    
pF1KE2 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI                
       :.::.:: :::::  : :.  .::..                                  
NP_001 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF
              310       320       330       340       350       360

>--
 initn: 385 init1: 284 opt: 290  Z-score: 214.9  bits: 48.8 E(85289): 3.1e-05
Smith-Waterman score: 290; 44.6% identity (73.3% similar) in 101 aa overlap (146-244:327-427)

         120       130       140       150       160       170     
pF1KE2 DTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTT
                                     ::.:...... . :::.: .::  .  . .
NP_001 YTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGIS
        300       310       320       330       340       350      

         180       190       200       210       220       230     
pF1KE2 YLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLY
         :. ..:::: : :..::.:: ::..  :::.:::.: ::. :: : :.:::. ::: :
NP_001 IRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNY
        360       370       380       390       400       410      

           240       250       260       270       280       290   
pF1KE2 G--PDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNN
       .  :.   .::                                                 
NP_001 NALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNH
        420       430       440       450       460       470      

>>NP_004354 (OMIM: 114890) carcinoembryonic antigen-rela  (702 aa)
 initn: 1833 init1: 1833 opt: 1833  Z-score: 1226.4  bits: 236.4 E(85289): 1.4e-61
Smith-Waterman score: 1833; 83.9% identity (92.6% similar) in 323 aa overlap (1-323:1-323)

               10        20        30        40        50        60
pF1KE2 MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ
       :  ::::: :  .::...::::::::::::::::::::::::::::::::::::.:::::
NP_004 MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY
       . .:::::::::::::  :.::::::::::::::::::: :::::::::::. :::::::
NP_004 HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV
       ::.:::::::::::::::.:::::::::::::::.:::::::::::::::.:..::::::
NP_004 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVP
       :.::::::::::::::: ::::..: :::..::.:: :::.:: ::: : ::::::::.:
NP_004 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ
       :::: ...:: :::::::::::::::::::::.:::::::::::::::::::::::: ::
NP_004 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ
              250       260       270       280       290       300

              310       320       330       340                    
pF1KE2 AHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI                
       :::: ::::::::: ::: .  :                                     
NP_004 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN
              310       320       330       340       350       360

>--
 initn: 904 init1: 840 opt: 916  Z-score: 624.4  bits: 125.0 E(85289): 4.8e-28
Smith-Waterman score: 916; 72.6% identity (82.1% similar) in 201 aa overlap (146-344:502-702)

         120       130       140       150       160       170     
pF1KE2 DTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTT
                                     :::::::::.:::::::::::::::.::::
NP_004 SGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTT
             480       490       500       510       520       530 

         180       190       200       210       220       230     
pF1KE2 YLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLY
       :::::::::::::::::::::: ::::..: :::: .: : ::: .::::::::::.:::
NP_004 YLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLY
             540       550       560       570       580       590 

         240       250       260       270       280       290     
pF1KE2 GPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSG
       :::.: :::  ..:  : :::::::.::::  :::: :::  :: :: ::: .:: ::.:
NP_004 GPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNG
             600       610       620       630       640       650 

         300       310         320       330       340    
pF1KE2 SYMCQAHNSATGLNRTTVTMITVS--GSAPVLSAVATVGITIGVLARVALI
       .: : . : ::: : . :  ::::  :..: ::: ::::: ::::. ::::
NP_004 TYACFVSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI
             660       670       680       690       700  

>--
 initn: 914 init1: 898 opt: 898  Z-score: 612.6  bits: 122.8 E(85289): 2.2e-27
Smith-Waterman score: 898; 75.8% identity (87.1% similar) in 178 aa overlap (146-323:324-501)

         120       130       140       150       160       170     
pF1KE2 DTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTT
                                     :: :.:::::::::.::::.:::::.::::
NP_004 SGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTT
           300       310       320       330       340       350   

         180       190       200       210       220       230     
pF1KE2 YLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLY
       ::::::.::::::::::::: : ::::::: :::.: ::: :::  :...:::: :::::
NP_004 YLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLY
           360       370       380       390       400       410   

         240       250       260       270       280       290     
pF1KE2 GPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSG
       ::: :::::: . :::: ::.:::::::::::::::.:.:..:: :::::: ::: .:::
NP_004 GPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSG
           420       430       440       450       460       470   

         300       310       320       330       340               
pF1KE2 SYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI           
        : :::.:::.: .::::  ::::.  :                                
NP_004 LYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYL
           480       490       500       510       520       530   




344 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 03:33:21 2016 done: Tue Nov  8 03:33:22 2016
 Total Scan time:  7.000 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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