Result of FASTA (omim) for
pF1KE2025
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2025, 608 aa
1>>>pF1KE2025 608 - 608 aa - 608 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2026+/-0.000348; mu= 16.4833+/- 0.022
mean_var=103.9305+/-21.229, 0's: 0 Z-trim(116.2): 65 B-trim: 27 in 1/51
Lambda= 0.125806
statistics sampled from 28150 (28223) to 28150 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.308), width: 16
Scan time: 4.810
The best scores are: opt bits E(91774)
NP_954592 (OMIM: 603934) histone-arginine methyltr ( 608) 4039 743.9 3.9e-214
NP_001357017 (OMIM: 603934) histone-arginine methy ( 585) 3592 662.8 1e-189
NP_001357018 (OMIM: 603934) histone-arginine methy ( 550) 3116 576.3 9.8e-164
XP_011525940 (OMIM: 603934) histone-arginine methy ( 447) 2965 548.9 1.5e-155
NP_001243465 (OMIM: 610086) protein arginine N-met ( 385) 648 128.3 5.2e-29
NP_062828 (OMIM: 610086) protein arginine N-methyl ( 394) 648 128.3 5.3e-29
NP_060607 (OMIM: 608274) protein arginine N-methyl ( 375) 647 128.1 5.7e-29
XP_024304080 (OMIM: 603190) protein arginine N-met ( 367) 642 127.2 1.1e-28
XP_016882225 (OMIM: 602950) protein arginine N-met ( 342) 641 127.0 1.1e-28
XP_005258899 (OMIM: 602950) protein arginine N-met ( 342) 641 127.0 1.1e-28
XP_016882223 (OMIM: 602950) protein arginine N-met ( 347) 641 127.0 1.1e-28
XP_016882224 (OMIM: 602950) protein arginine N-met ( 347) 641 127.0 1.1e-28
NP_938074 (OMIM: 602950) protein arginine N-methyl ( 353) 641 127.0 1.2e-28
XP_011518138 (OMIM: 603190) protein arginine N-met ( 426) 642 127.2 1.2e-28
NP_001527 (OMIM: 602950) protein arginine N-methyl ( 371) 641 127.0 1.2e-28
NP_001138639 (OMIM: 603190) protein arginine N-met ( 454) 642 127.3 1.3e-28
NP_001138638 (OMIM: 603190) protein arginine N-met ( 469) 642 127.3 1.3e-28
XP_016872570 (OMIM: 603190) protein arginine N-met ( 498) 642 127.3 1.3e-28
NP_005779 (OMIM: 603190) protein arginine N-methyl ( 531) 642 127.3 1.4e-28
NP_996845 (OMIM: 601961) protein arginine N-methyl ( 433) 625 124.2 1e-27
NP_001526 (OMIM: 601961) protein arginine N-methyl ( 433) 625 124.2 1e-27
XP_005261168 (OMIM: 601961) protein arginine N-met ( 433) 625 124.2 1e-27
XP_024304827 (OMIM: 610086) protein arginine N-met ( 309) 524 105.7 2.6e-22
NP_001229795 (OMIM: 601961) protein arginine N-met ( 277) 461 94.2 6.6e-19
NP_001273606 (OMIM: 601961) protein arginine N-met ( 289) 461 94.3 6.8e-19
NP_001193971 (OMIM: 602950) protein arginine N-met ( 285) 419 86.6 1.3e-16
XP_016883829 (OMIM: 601961) protein arginine N-met ( 247) 367 77.1 8.2e-14
XP_016883828 (OMIM: 601961) protein arginine N-met ( 247) 367 77.1 8.2e-14
NP_001229793 (OMIM: 601961) protein arginine N-met ( 331) 368 77.4 9.1e-14
NP_001273605 (OMIM: 601961) protein arginine N-met ( 301) 367 77.2 9.6e-14
XP_006724061 (OMIM: 601961) protein arginine N-met ( 301) 367 77.2 9.6e-14
NP_001273607 (OMIM: 601961) protein arginine N-met ( 228) 361 76.0 1.6e-13
XP_006724063 (OMIM: 601961) protein arginine N-met ( 228) 361 76.0 1.6e-13
NP_001229794 (OMIM: 601961) protein arginine N-met ( 284) 362 76.3 1.7e-13
XP_006724062 (OMIM: 601961) protein arginine N-met ( 287) 359 75.7 2.5e-13
XP_016875134 (OMIM: 610086) protein arginine N-met ( 321) 352 74.5 6.7e-13
XP_016875133 (OMIM: 610086) protein arginine N-met ( 369) 352 74.6 7.4e-13
NP_001337071 (OMIM: 616125) protein arginine N-met ( 732) 224 51.5 1.3e-05
NP_001291387 (OMIM: 616125) protein arginine N-met ( 732) 224 51.5 1.3e-05
NP_612373 (OMIM: 616125) protein arginine N-methyl ( 845) 224 51.6 1.4e-05
XP_016878801 (OMIM: 610087,617157) protein arginin ( 479) 217 50.1 2.2e-05
XP_016878793 (OMIM: 610087,617157) protein arginin ( 627) 217 50.2 2.7e-05
XP_016878790 (OMIM: 610087,617157) protein arginin ( 639) 217 50.2 2.7e-05
XP_016878789 (OMIM: 610087,617157) protein arginin ( 640) 217 50.2 2.7e-05
XP_016878788 (OMIM: 610087,617157) protein arginin ( 648) 217 50.2 2.7e-05
XP_016878787 (OMIM: 610087,617157) protein arginin ( 670) 217 50.2 2.8e-05
XP_016878786 (OMIM: 610087,617157) protein arginin ( 686) 217 50.2 2.9e-05
XP_016878785 (OMIM: 610087,617157) protein arginin ( 687) 217 50.2 2.9e-05
NP_061896 (OMIM: 610087,617157) protein arginine N ( 692) 217 50.2 2.9e-05
XP_016878784 (OMIM: 610087,617157) protein arginin ( 692) 217 50.2 2.9e-05
>>NP_954592 (OMIM: 603934) histone-arginine methyltransf (608 aa)
initn: 4039 init1: 4039 opt: 4039 Z-score: 3965.9 bits: 743.9 E(91774): 3.9e-214
Smith-Waterman score: 4039; 100.0% identity (100.0% similar) in 608 aa overlap (1-608:1-608)
10 20 30 40 50 60
pF1KE2 MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP
550 560 570 580 590 600
pF1KE2 TNTMHYGS
::::::::
NP_954 TNTMHYGS
>>NP_001357017 (OMIM: 603934) histone-arginine methyltra (585 aa)
initn: 3619 init1: 3592 opt: 3592 Z-score: 3527.7 bits: 662.8 E(91774): 1e-189
Smith-Waterman score: 3837; 96.2% identity (96.2% similar) in 608 aa overlap (1-608:1-585)
10 20 30 40 50 60
pF1KE2 MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPL--
490 500 510 520 530
550 560 570 580 590 600
pF1KE2 TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP
:::::::::::::::::::::::::::::::::::::::
NP_001 ---------------------GSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP
540 550 560 570
pF1KE2 TNTMHYGS
::::::::
NP_001 TNTMHYGS
580
>>NP_001357018 (OMIM: 603934) histone-arginine methyltra (550 aa)
initn: 3134 init1: 3107 opt: 3116 Z-score: 3061.1 bits: 576.3 E(91774): 9.8e-164
Smith-Waterman score: 3361; 94.0% identity (94.5% similar) in 549 aa overlap (61-608:28-550)
40 50 60 70 80
pF1KE2 VFPGARLLTIGDANGEIQRHAEQQALRLEVRAGP-DSAGIALYSHEDVCVFKCSVSRETE
: :: .::. .:::::::::::::::
NP_001 MGNFRIWGEGPCGDGGSRRVSSSWKRGRDGPLPDAGL---RNEDVCVFKCSVSRETE
10 20 30 40 50
90 100 110 120 130 140
pF1KE2 CSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQY
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE2 FQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARK
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE2 IYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERML
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE2 ESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGA
240 250 260 270 280 290
330 340 350 360 370 380
pF1KE2 AVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAF
300 310 320 330 340 350
390 400 410 420 430 440
pF1KE2 WFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYD
360 370 380 390 400 410
450 460 470 480 490 500
pF1KE2 ISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGM
420 430 440 450 460 470
510 520 530 540 550 560
pF1KE2 AVAGMPTAYDLSSVIASGSSVGHNNLIPLANTGIVNHTHSRMGSIMSTGIVQGSSGAQGS
::::::::::::::::::::::::::::: ::::::::
NP_001 AVAGMPTAYDLSSVIASGSSVGHNNLIPL-----------------------GSSGAQGS
480 490 500 510
570 580 590 600
pF1KE2 GGGSTSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS
:::::::::::::::::::::::::::::::::::::::
NP_001 GGGSTSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS
520 530 540 550
>>XP_011525940 (OMIM: 603934) histone-arginine methyltra (447 aa)
initn: 2965 init1: 2965 opt: 2965 Z-score: 2914.3 bits: 548.9 E(91774): 1.5e-155
Smith-Waterman score: 2965; 100.0% identity (100.0% similar) in 447 aa overlap (162-608:1-447)
140 150 160 170 180 190
pF1KE2 LERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDV
::::::::::::::::::::::::::::::
XP_011 MMQDYVRTGTYQRAILQNHTDFKDKIVLDV
10 20 30
200 210 220 230 240 250
pF1KE2 GCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQV
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 DIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKAN
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 FWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIE
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE2 IPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAG
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE2 DTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTS
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE2 PSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLANTGIVNHTHSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLANTGIVNHTHSRM
340 350 360 370 380 390
560 570 580 590 600
pF1KE2 GSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIPTNTMHYGS
400 410 420 430 440
>>NP_001243465 (OMIM: 610086) protein arginine N-methylt (385 aa)
initn: 570 init1: 328 opt: 648 Z-score: 642.4 bits: 128.3 E(91774): 5.2e-29
Smith-Waterman score: 648; 33.5% identity (65.9% similar) in 352 aa overlap (112-460:31-371)
90 100 110 120 130 140
pF1KE2 CSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERT
: : . . .: :. .... .
NP_001 MESLASDGFKLKEVSSVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPE-
10 20 30 40 50
150 160 170 180 190 200
pF1KE2 EESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFF
: .: ::. :.... ...:..: ::: ::. .. .:. ::::.::::: :.::::.:
NP_001 EMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMF
60 70 80 90 100 110
210 220 230 240 250 260
pF1KE2 AAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMG
::.:::.:....: :......: ..:.:.: . :... :::::: :: :.::::::: ::
NP_001 AAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMG
120 130 140 150 160 170
270 280 290 300 310
pF1KE2 YMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH
: :: : ::.. . :. :.:::.: ::: . .... . :.: ...: : ..: . .
NP_001 YCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQ--YKDF-KIHWW--ENVY
180 190 200 210 220 230
320 330 340 350 360 370
pF1KE2 GVDLSALRGAAVDEYFRQPVVDTFDIR-ILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHM
: :.. .: .:. : :.:: : . .. . :.. .: .: . : ...
NP_001 GFDMTCIRDVAMKE----PLVDIVDPKQVVTNACLIKEVDIYTVKTEELS-FTSAFCLQI
240 250 260 270 280
380 390 400 410 420 430
pF1KE2 LHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTC
.. ::.:. .:.. : . .:::: : ::: :. ... : .. :. . ::
NP_001 QRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTI
290 300 310 320 330 340
440 450 460 470 480 490
pF1KE2 LLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWN
. : .. :.......: :
NP_001 SMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR
350 360 370 380
>>NP_062828 (OMIM: 610086) protein arginine N-methyltran (394 aa)
initn: 570 init1: 328 opt: 648 Z-score: 642.3 bits: 128.3 E(91774): 5.3e-29
Smith-Waterman score: 648; 33.5% identity (65.9% similar) in 352 aa overlap (112-460:40-380)
90 100 110 120 130 140
pF1KE2 CSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERT
: : . . .: :. .... .
NP_062 LLLRRKMAENAAESTEVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPE-
10 20 30 40 50 60
150 160 170 180 190 200
pF1KE2 EESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFF
: .: ::. :.... ...:..: ::: ::. .. .:. ::::.::::: :.::::.:
NP_062 EMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMF
70 80 90 100 110 120
210 220 230 240 250 260
pF1KE2 AAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMG
::.:::.:....: :......: ..:.:.: . :... :::::: :: :.::::::: ::
NP_062 AAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMG
130 140 150 160 170 180
270 280 290 300 310
pF1KE2 YMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH
: :: : ::.. . :. :.:::.: ::: . .... . :.: ...: : ..: . .
NP_062 YCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQ--YKDF-KIHWW--ENVY
190 200 210 220 230 240
320 330 340 350 360 370
pF1KE2 GVDLSALRGAAVDEYFRQPVVDTFDIR-ILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHM
: :.. .: .:. : :.:: : . .. . :.. .: .: . : ...
NP_062 GFDMTCIRDVAMKE----PLVDIVDPKQVVTNACLIKEVDIYTVKTEELS-FTSAFCLQI
250 260 270 280 290
380 390 400 410 420 430
pF1KE2 LHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTC
.. ::.:. .:.. : . .:::: : ::: :. ... : .. :. . ::
NP_062 QRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTI
300 310 320 330 340 350
440 450 460 470 480 490
pF1KE2 LLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWN
. : .. :.......: :
NP_062 SMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR
360 370 380 390
>>NP_060607 (OMIM: 608274) protein arginine N-methyltran (375 aa)
initn: 558 init1: 436 opt: 647 Z-score: 641.6 bits: 128.1 E(91774): 5.7e-29
Smith-Waterman score: 647; 35.8% identity (65.6% similar) in 352 aa overlap (128-469:29-371)
100 110 120 130 140 150
pF1KE2 FIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLS
: .::: .::.. :.. :. .:
NP_060 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALER---PRRTKRERDQLYYECYSDVS
10 20 30 40 50
160 170 180 190 200 210
pF1KE2 QQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEAST
...:. : ::: .:. .::.: . .. : ::::: :.::::.: ::::::..::::::.
NP_060 VHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA
60 70 80 90 100 110
220 230 240 250 260 270
pF1KE2 MAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAK-
. :.:. .:. :.: ::. :.:: :: : :::::: :.:: ::: :..: :: : :::.
NP_060 IWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHART
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE2 KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH-GVDLSALRGAAVDEYF
:.:: .: ..:. ... .::..:..: . .:: : . : :::.: :.: :. .
NP_060 KWLKEGGLLLPASAELFIAPISDQMLEW----RLGFWSQVKQHYGVDMSCLEGFATRCLM
180 190 200 210 220 230
340 350 360 370 380
pF1KE2 --RQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIP----FKFHMLHSGLVHGLAF
. ::. .. . ..:. ... .. .. : ...: :. :. .::.:.
NP_060 GHSEIVVQGLSGEDVLARPQRFA-QLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAI
240 250 260 270 280 290
390 400 410 420 430 440
pF1KE2 WFDVAFIG--SIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQS
::.:.: : : . :::.: .: ::: :. .. :. .. .:: :. .. .
NP_060 WFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNP
300 310 320 330 340 350
450 460 470 480 490 500
pF1KE2 YDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSS
. .. . ..:.. . :.
NP_060 RRLRVLLRY-KVGDQEEKTKDFAMED
360 370
>>XP_024304080 (OMIM: 603190) protein arginine N-methylt (367 aa)
initn: 595 init1: 328 opt: 642 Z-score: 636.8 bits: 127.2 E(91774): 1.1e-28
Smith-Waterman score: 642; 34.4% identity (67.0% similar) in 355 aa overlap (110-459:24-360)
80 90 100 110 120 130
pF1KE2 FKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSE
::: .:: .. .:: . : ::...
XP_024 MEARALSAEAALARAREDLQKMKQFA--QDFVMHTDV-RTCSSST---SVIAD
10 20 30 40
140 150 160 170 180 190
pF1KE2 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS
:. ..: ::. ::. . ...:..: .:: .:. : :: ::::.:::::::.::::
XP_024 LQEDEDGV-YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS
50 60 70 80 90 100
200 210 220 230 240 250
pF1KE2 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEP
.:::.:::.:. .:. : . .: ... :.: : :..: ::.::: :: :.::.::::
XP_024 MFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEW
110 120 130 140 150 160
260 270 280 290 300 310
pF1KE2 MGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPS
:::.:. : ::.: :.:: ::: .:...: : . :. .: . . . . :: .
XP_024 MGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHAD---RIAFW--DD
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE2 FHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK--SVKYTVNFLEAKEGDLHRIEIPFK
.: .: .. :.. : ::...: . :... ..:. .. .. .::. . :
XP_024 VYGFKMSCMKKAVIPE----AVVEVLDPKTLISEPCGIKH-IDCHTTSISDLE-FSSDFT
230 240 250 260 270
380 390 400 410 420 430
pF1KE2 FHMLHSGLVHGLAFWFDVAFIGSIMT-VWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTL
... .... ..: .::. : . . : .::.: ::: :. :...:. .:::..:
XP_024 LKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEAL
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 SGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSE
.: . ::.. ..... ....
XP_024 KGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ
340 350 360
>>XP_016882225 (OMIM: 602950) protein arginine N-methylt (342 aa)
initn: 518 init1: 320 opt: 641 Z-score: 636.3 bits: 127.0 E(91774): 1.1e-28
Smith-Waterman score: 641; 35.9% identity (68.8% similar) in 320 aa overlap (144-460:19-328)
120 130 140 150 160 170
pF1KE2 PNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQ
.: ::. :.... ...:..: ::: ::.
XP_016 MVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYR
10 20 30 40
180 190 200 210 220 230
pF1KE2 RAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTD
....:. ::::.::::: :.::: .:::.:::::. ..: :.....: .::.:.:
XP_016 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDH
50 60 70 80 90 100
240 250 260 270 280 290
pF1KE2 RIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGD
...: :::::: :: :.::::::: ::: :: : ::.. :.:. :.: :.: .:: .
XP_016 VVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRAT
110 120 130 140 150 160
300 310 320 330 340 350
pF1KE2 VHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK
.... . :.: : . : ..: . .: :.: .. .:. ..:.::. : . :...
XP_016 LYVTAIEDRQ-YKDY--KIHWW--ENVYGFDMSCIKDVAI----KEPLVDVVDPKQLVTN
170 180 190 200 210
360 370 380 390 400 410
pF1KE2 S-VKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTE
. . :.. .: :: . :: ... .. ::.:. .:.. : . .::.:
XP_016 ACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPES
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE2 PLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLK
: ::: :. ... : .:.:. . :: . : ... :.... ..: :
XP_016 PYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTD
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE2 NPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSV
XP_016 YRMR
340
>>XP_005258899 (OMIM: 602950) protein arginine N-methylt (342 aa)
initn: 518 init1: 320 opt: 641 Z-score: 636.3 bits: 127.0 E(91774): 1.1e-28
Smith-Waterman score: 641; 35.9% identity (68.8% similar) in 320 aa overlap (144-460:19-328)
120 130 140 150 160 170
pF1KE2 PNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQ
.: ::. :.... ...:..: ::: ::.
XP_005 MVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYR
10 20 30 40
180 190 200 210 220 230
pF1KE2 RAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTD
....:. ::::.::::: :.::: .:::.:::::. ..: :.....: .::.:.:
XP_005 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDH
50 60 70 80 90 100
240 250 260 270 280 290
pF1KE2 RIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGD
...: :::::: :: :.::::::: ::: :: : ::.. :.:. :.: :.: .:: .
XP_005 VVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRAT
110 120 130 140 150 160
300 310 320 330 340 350
pF1KE2 VHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK
.... . :.: : . : ..: . .: :.: .. .:. ..:.::. : . :...
XP_005 LYVTAIEDRQ-YKDY--KIHWW--ENVYGFDMSCIKDVAI----KEPLVDVVDPKQLVTN
170 180 190 200 210
360 370 380 390 400 410
pF1KE2 S-VKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTE
. . :.. .: :: . :: ... .. ::.:. .:.. : . .::.:
XP_005 ACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPES
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE2 PLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLK
: ::: :. ... : .:.:. . :: . : ... :.... ..: :
XP_005 PYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTD
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE2 NPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSV
XP_005 YRMR
340
608 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 16:06:48 2019 done: Tue Jul 16 16:06:49 2019
Total Scan time: 4.810 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]