Result of FASTA (omim) for pF1KB7819
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7819, 535 aa
  1>>>pF1KB7819     535 - 535 aa - 535 aa
Library: /omim/omim.rfq.tfa
  64369986 residues in 92320 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.2359+/-0.000373; mu= 2.7439+/- 0.023
 mean_var=280.9192+/-57.408, 0's: 0 Z-trim(122.9): 72  B-trim: 760 in 1/53
 Lambda= 0.076522
 statistics sampled from 43470 (43544) to 43470 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.472), width:  16
 Scan time:  5.510

The best scores are:                                      opt bits E(92320)
NP_037483 (OMIM: 208550,604895) T-box transcriptio ( 535) 3821 435.2 2.7e-121
NP_001265111 (OMIM: 604615) eomesodermin homolog i ( 705) 1145 139.9 2.8e-32
NP_006584 (OMIM: 604616,606053) T-box brain protei ( 682) 1127 137.9 1.1e-31
XP_005265567 (OMIM: 604615) eomesodermin homolog i ( 515) 1096 134.3 9.4e-31
NP_005433 (OMIM: 604615) eomesodermin homolog isof ( 686) 1083 133.0 3.1e-30
NP_001265112 (OMIM: 604615) eomesodermin homolog i ( 410)  935 116.4 1.8e-25
XP_011523797 (OMIM: 147891,601719) T-box transcrip ( 417)  716 92.3 3.4e-18
XP_016884414 (OMIM: 187500,188400,192430,217095,60 ( 545)  717 92.5 3.8e-18
NP_542378 (OMIM: 187500,188400,192430,217095,60205 ( 495)  716 92.3 3.9e-18
XP_016884415 (OMIM: 187500,188400,192430,217095,60 ( 495)  716 92.3 3.9e-18
XP_006724375 (OMIM: 187500,188400,192430,217095,60 ( 495)  716 92.3 3.9e-18
XP_011523793 (OMIM: 147891,601719) T-box transcrip ( 608)  716 92.4 4.5e-18
XP_011523792 (OMIM: 147891,601719) T-box transcrip ( 609)  716 92.4 4.5e-18
NP_060958 (OMIM: 147891,601719) T-box transcriptio ( 545)  713 92.1 5.2e-18
NP_001308049 (OMIM: 147891,601719) T-box transcrip ( 546)  713 92.1 5.2e-18
NP_005983 (OMIM: 187500,188400,192430,217095,60205 ( 372)  697 90.1 1.4e-17
NP_542377 (OMIM: 187500,188400,192430,217095,60205 ( 398)  697 90.2 1.4e-17
XP_016884417 (OMIM: 187500,188400,192430,217095,60 ( 448)  698 90.3 1.4e-17
XP_016875401 (OMIM: 142900,601620) T-box transcrip ( 534)  692 89.7 2.6e-17
NP_000183 (OMIM: 142900,601620) T-box transcriptio ( 518)  685 88.9 4.3e-17
NP_852259 (OMIM: 142900,601620) T-box transcriptio ( 518)  685 88.9 4.3e-17
NP_542448 (OMIM: 142900,601620) T-box transcriptio ( 468)  682 88.6   5e-17
NP_005985 (OMIM: 600747,618223) T-box transcriptio ( 712)  679 88.4 8.5e-17
NP_004599 (OMIM: 122600,602427) T-box transcriptio ( 436)  663 86.4   2e-16
XP_005255580 (OMIM: 122600,602427) T-box transcrip ( 436)  663 86.4   2e-16
XP_016879103 (OMIM: 122600,602427) T-box transcrip ( 436)  663 86.4   2e-16
XP_011544228 (OMIM: 122600,602427) T-box transcrip ( 436)  663 86.4   2e-16
XP_011543294 (OMIM: 604648) T-box transcription fa ( 430)  640 83.9 1.2e-15
XP_006715665 (OMIM: 143400,604613) T-box transcrip ( 364)  636 83.4 1.4e-15
XP_011534551 (OMIM: 143400,604613) T-box transcrip ( 372)  636 83.4 1.4e-15
XP_016866962 (OMIM: 143400,604613) T-box transcrip ( 376)  636 83.4 1.5e-15
XP_011534550 (OMIM: 143400,604613) T-box transcrip ( 377)  636 83.4 1.5e-15
NP_005987 (OMIM: 181450,601621) T-box transcriptio ( 723)  642 84.3 1.5e-15
XP_011534549 (OMIM: 143400,604613) T-box transcrip ( 379)  636 83.4 1.5e-15
NP_005986 (OMIM: 604648) T-box transcription facto ( 385)  634 83.2 1.7e-15
NP_001073977 (OMIM: 143400,604613) T-box transcrip ( 607)  636 83.6   2e-15
XP_016877519 (OMIM: 616061) MAX gene-associated pr (2207)  624 82.8 1.3e-14
NP_001074010 (OMIM: 616061) MAX gene-associated pr (2856)  624 82.9 1.5e-14
XP_005254310 (OMIM: 616061) MAX gene-associated pr (2906)  624 82.9 1.5e-14
XP_005254309 (OMIM: 616061) MAX gene-associated pr (2956)  624 82.9 1.6e-14
XP_011519700 (OMIM: 616061) MAX gene-associated pr (3004)  624 83.0 1.6e-14
XP_011519699 (OMIM: 616061) MAX gene-associated pr (3005)  624 83.0 1.6e-14
NP_001157745 (OMIM: 616061) MAX gene-associated pr (3065)  624 83.0 1.6e-14
XP_005254306 (OMIM: 616061) MAX gene-associated pr (3066)  624 83.0 1.6e-14
XP_005254305 (OMIM: 616061) MAX gene-associated pr (3114)  624 83.0 1.6e-14
XP_005254302 (OMIM: 616061) MAX gene-associated pr (3115)  624 83.0 1.6e-14
XP_005254301 (OMIM: 616061) MAX gene-associated pr (3115)  624 83.0 1.6e-14
XP_006720506 (OMIM: 616061) MAX gene-associated pr (3115)  624 83.0 1.6e-14
XP_005254303 (OMIM: 616061) MAX gene-associated pr (3115)  624 83.0 1.6e-14
XP_005254300 (OMIM: 616061) MAX gene-associated pr (3115)  624 83.0 1.6e-14


>>NP_037483 (OMIM: 208550,604895) T-box transcription fa  (535 aa)
 initn: 3821 init1: 3821 opt: 3821  Z-score: 2299.3  bits: 435.2 E(92320): 2.7e-121
Smith-Waterman score: 3821; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535)

               10        20        30        40        50        60
pF1KB7 MGIVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MGIVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 SHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 KLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 AVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 AVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 NQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 NQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 RGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEI
              430       440       450       460       470       480

              490       500       510       520       530     
pF1KB7 APIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 APIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
              490       500       510       520       530     

>>NP_001265111 (OMIM: 604615) eomesodermin homolog isofo  (705 aa)
 initn: 1143 init1: 1006 opt: 1145  Z-score: 701.2  bits: 139.9 E(92320): 2.8e-32
Smith-Waterman score: 1225; 44.5% identity (63.1% similar) in 539 aa overlap (34-512:143-674)

            10        20        30        40                  50   
pF1KB7 VEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDAD----------ERRGGGS
                                     ::.   :: : ..          .  .:. 
NP_001 ELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAP
            120       130       140       150       160       170  

              60            70        80        90        100      
pF1KB7 LGS--PYPGGALVPA----PPSRFLGAYAYPPRPQAAGFPGAGE-SFPPPADAEGYQPGE
        :   : :.::  :     ::. : .:   : : : .  ::::  :    ... :  :: 
NP_001 HGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFG--PGAGAGSGAGGSSGGGGGPGT
            180       190       200         210       220       230

         110       120         130          140       150       160
pF1KB7 -GYAAPDPRAGLYPGPREDYALPA--GLEVSG---KLRVALNNHLLWSKFNQHQTEMIIT
         :.   :  : :::     .  .  :: : :   . .: : :. :: ::..::::::::
NP_001 YQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT
              240       250       260       270       280       290

              170       180       190       200       210       220
pF1KB7 KQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLY
       ::::::::::::.. ::.::.:: .::.:::.: .:::.:.:::: ::::...: ::..:
NP_001 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMY
              300       310       320       330       340       350

              230       240       250       260       270       280
pF1KB7 VHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEP
       :::.:::::.::::::.:::::::::::::.:: :::::::::::::::::::::..   
NP_001 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV
              360       370       380       390       400       410

              290       300       310       320       330          
pF1KB7 EAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSV--DTS
       :   . :.:. :::.::::::::::::..:::::::.::::::::.:..::::.   :  
NP_001 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRL
              420       430       440       450       460       470

      340         350         360          370                  380
pF1KB7 IPSPP-GPNC-QFLGGDHYS--PLLPNQY--PVP-SRFY------PDL-----PGQAKDV
        :::  .:   :.. : .:.   ..:. .   .: .:.:      :.      : :...:
NP_001 TPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEV
              480       490       500       510       520       530

               390                400       410          420       
pF1KB7 V-PQAYWLGAPRDH---------SYEAEFRAVSMKPAFLPSAPGPT---MSYYRGQEVLA
       . :   :: .: ..         :::.:. . .. :  . : :  :   ..::  . .. 
NP_001 ANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYY-PDPTFP
              540       550       560       570       580          

       430       440        450       460        470       480     
pF1KB7 PGAGWPVAPQYPPKMGPA-SWFRPMRTLPMEPGPGG-SEGRGPEDQGPPLVWTEIAP-IR
         :::    .:  ::. .  :    :: :   .    :. .  :. :    : :  : :.
NP_001 AMAGWGGRGSYQRKMAAGLPWTS--RTSPTVFSEDQLSKEKVKEEIGSS--WIETPPSIK
     590       600       610         620       630         640     

           490       500       510       520       530             
pF1KB7 P-ESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN        
         .:.:::.  .  ::::.::  ::...:                               
NP_001 SLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
         650       660       670       680       690       700     

>>NP_006584 (OMIM: 604616,606053) T-box brain protein 1   (682 aa)
 initn: 1077 init1: 1025 opt: 1127  Z-score: 690.7  bits: 137.9 E(92320): 1.1e-31
Smith-Waterman score: 1142; 42.8% identity (64.6% similar) in 495 aa overlap (57-527:125-588)

         30        40        50        60        70        80      
pF1KB7 PGADPQHRYFYPEPGAQDADERRGGGSLGSPYPGGALVPAPPSRFLGAYAYPPRPQAAGF
                                     ::::    :: :.  .:.   : :   :  
NP_006 HSFDGSAADRYLLSQSSQPQSAATAPSAMFPYPGQHG-PAHPAFSIGS---PSR-YMAHH
          100       110       120       130        140             

             90       100       110       120        130       140 
pF1KB7 P----GAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG-PREDYALPAGLEVSGKLRVAL
       :    :: .:.   .. .:: :  ::  :.  .  : : :  ...      : :: .: :
NP_006 PVITNGAYNSLLSNSSPQGY-PTAGYPYPQQYGHSYQGAPFYQFSSTQPGLVPGKAQVYL
     150       160        170       180       190       200        

             150       160       170       180       190       200 
pF1KB7 NNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQS
        :. :: ::..::::::::::::::::::::...::.::.:: .::::.:.: .:::.:.
NP_006 CNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWRFQG
      210       220       230       240       250       260        

             210       220       230       240       250       260 
pF1KB7 GKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQ
       :::: ::::. .. :::.:.:::::::::::::::.::::::::::::::::  ::.:::
NP_006 GKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGASNNNGQMVVLQ
      270       280       290       300       310       320        

             270       280       290       300       310       320 
pF1KB7 SLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFA
       ::::::::::.::::.   : . . . .. ::: ::::::::::::..:::::::.::::
NP_006 SLHKYQPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFA
      330       340       350       360       370       380        

             330         340        350          360          370  
pF1KB7 KGFRENFESMYTSVDTS--IPSP-PGPNCQFLGGDHYS---PLLPNQYP---VPSRFYPD
       ::::.:....::. : .   :::  .:  :.. : .:.    .: .:.    . .::.: 
NP_006 KGFRDNYDTIYTGCDMDRLTPSPNDSPRSQIVPGARYAMAGSFLQDQFVSNYAKARFHPG
      390       400       410       420       430       440        

                380       390       400       410       420        
pF1KB7 L---PGQAKD-VVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYYR--GQEVL
           :: . :  ::..  : .:.    .::           :.::.:   .    .... 
NP_006 AGAGPGPGTDRSVPHTNGLLSPQ----QAE----------DPGAPSPQRWFVTPANNRLD
      450       460       470                     480       490    

        430       440       450         460       470       480    
pF1KB7 APGAGWPVAPQYPPKMGPASWFRP--MRTLPMEPGPGGSEGRGPEDQGPPLVWTEIAPIR
         .... .: ..  . .    .    ...::..   .:  ::     . :  :   .: .
NP_006 FAASAYDTATDFAGNAATLLSYAAAGVKALPLQA--AGCTGRPLGYYADPSGWGARSPPQ
          500       510       520         530       540       550  

          490       500        510       520        530            
pF1KB7 PESSDSGLGEGDSKRRRVSP-YPSSGDSSSPAGAPSPF-DKEAEGQFYNYFPN       
         .. ::          : : .:.:. ...  .. .:.  .::::               
NP_006 YCGTKSG---------SVLPCWPNSAAAAARMAGANPYLGEEAEGLAAERSPLPPGAAED
                     560       570       580       590       600   

NP_006 AKPKDLSDSSWIETPSSIKSIDSSDSGIYEQAKRRRISPADTPVSESSSPLKSEVLAQRD
           610       620       630       640       650       660   

>>XP_005265567 (OMIM: 604615) eomesodermin homolog isofo  (515 aa)
 initn: 1082 init1: 992 opt: 1096  Z-score: 673.7  bits: 134.3 E(92320): 9.4e-31
Smith-Waterman score: 1100; 55.1% identity (71.0% similar) in 334 aa overlap (34-342:143-474)

            10        20        30        40                  50   
pF1KB7 VEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDAD----------ERRGGGS
                                     ::.   :: : ..          .  .:. 
XP_005 ELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAP
            120       130       140       150       160       170  

              60            70        80        90        100      
pF1KB7 LGS--PYPGGALVPA----PPSRFLGAYAYPPRPQAAGFPGAGE-SFPPPADAEGYQPGE
        :   : :.::  :     ::. : .:   : : : .  ::::  :    ... :  :: 
XP_005 HGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFG--PGAGAGSGAGGSSGGGGGPGT
            180       190       200         210       220       230

         110       120         130          140       150       160
pF1KB7 -GYAAPDPRAGLYPGPREDYALPA--GLEVSG---KLRVALNNHLLWSKFNQHQTEMIIT
         :.   :  : :::     .  .  :: : :   . .: : :. :: ::..::::::::
XP_005 YQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT
              240       250       260       270       280       290

              170       180       190       200       210       220
pF1KB7 KQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLY
       ::::::::::::.. ::.::.:: .::.:::.: .:::.:.:::: ::::...: ::..:
XP_005 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMY
              300       310       320       330       340       350

              230       240       250       260       270       280
pF1KB7 VHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEP
       :::.:::::.::::::.:::::::::::::.:: :::::::::::::::::::::..   
XP_005 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV
              360       370       380       390       400       410

              290       300       310       320       330          
pF1KB7 EAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSV--DTS
       :   . :.:. :::.::::::::::::..:::::::.::::::::.:..::::.   :  
XP_005 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRL
              420       430       440       450       460       470

      340       350       360       370       380       390        
pF1KB7 IPSPPGPNCQFLGGDHYSPLLPNQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAE
        :::                                                        
XP_005 TPSPTDSPRSHQIVPGERRGGQPSPAVACHACPATWDQQTRHQFL               
              480       490       500       510                    

>>NP_005433 (OMIM: 604615) eomesodermin homolog isoform   (686 aa)
 initn: 1137 init1: 972 opt: 1083  Z-score: 664.4  bits: 133.0 E(92320): 3.1e-30
Smith-Waterman score: 1190; 44.3% identity (62.2% similar) in 526 aa overlap (34-512:143-655)

            10        20        30        40                  50   
pF1KB7 VEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDAD----------ERRGGGS
                                     ::.   :: : ..          .  .:. 
NP_005 ELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAP
            120       130       140       150       160       170  

              60            70        80        90        100      
pF1KB7 LGS--PYPGGALVPA----PPSRFLGAYAYPPRPQAAGFPGAGE-SFPPPADAEGYQPGE
        :   : :.::  :     ::. : .:   : : : .  ::::  :    ... :  :: 
NP_005 HGPVYPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFG--PGAGAGSGAGGSSGGGGGPGT
            180       190       200         210       220       230

         110       120         130          140       150       160
pF1KB7 -GYAAPDPRAGLYPGPREDYALPA--GLEVSG---KLRVALNNHLLWSKFNQHQTEMIIT
         :.   :  : :::     .  .  :: : :   . .: : :. :: ::..::::::::
NP_005 YQYSQGAPLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT
              240       250       260       270       280       290

              170       180       190       200       210       220
pF1KB7 KQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLY
       ::::::::::::.. ::.::.:: .::.:::.: .:::.:.:::: ::::...: ::..:
NP_005 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNKMY
              300       310       320       330       340       350

              230       240       250       260       270       280
pF1KB7 VHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEP
       :::.:::::.::::::.:::::::::::::.:: :::::::::::::::::::::..   
NP_005 VHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGV
              360       370       380       390       400       410

              290       300       310       320       330       340
pF1KB7 EAACNASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIP
       :   . :.:. :::.::::::::::::..:::::::.::::::::.:..: .  :     
NP_005 EDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSSHQIV-----
              420       430       440       450       460          

               350       360        370            380        390  
pF1KB7 SPPGP-NCQFLGGDHYSPLLPN-QYPVPSRFYPDL-----PGQAKDVV-PQAYWLGAPRD
        : :  . : .  . .   ::. .:    :  :.      : :...:. :   :: .: .
NP_005 -PGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQ
          470       480       490       500       510       520    

                     400       410          420       430       440
pF1KB7 H---------SYEAEFRAVSMKPAFLPSAPGPT---MSYYRGQEVLAPGAGWPVAPQYPP
       .         :::.:. . .. :  . : :  :   ..::  . ..   :::    .:  
NP_005 QPGTNKLDISSYESEYTSSTLLPYGIKSLPLQTSHALGYY-PDPTFPAMAGWGGRGSYQR
          530       540       550       560        570       580   

               450       460        470       480         490      
pF1KB7 KMGPA-SWFRPMRTLPMEPGPGG-SEGRGPEDQGPPLVWTEIAP-IRP-ESSDSGLGEGD
       ::. .  :    :: :   .    :. .  :. :    : :  : :.  .:.:::.  . 
NP_005 KMAAGLPWTS--RTSPTVFSEDQLSKEKVKEEIGSS--WIETPPSIKSLDSNDSGVYTSA
           590         600       610         620       630         

        500       510       520       530             
pF1KB7 SKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN        
        ::::.::  ::...:                               
NP_005 CKRRRLSPSNSSNENSPSIKCEDINAEEYSKDTSKGMGGYYAFYTTP
     640       650       660       670       680      

>>NP_001265112 (OMIM: 604615) eomesodermin homolog isofo  (410 aa)
 initn: 953 init1: 878 opt: 935  Z-score: 578.9  bits: 116.4 E(92320): 1.8e-25
Smith-Waterman score: 1011; 47.7% identity (68.2% similar) in 384 aa overlap (166-512:1-379)

         140       150       160       170       180       190     
pF1KB7 KLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQH
                                     :::::::.. ::.::.:: .::.:::.: .
NP_001                               MFPFLSFNINGLNPTAHYNVFVEVVLADPN
                                             10        20        30

         200       210       220       230       240       250     
pF1KB7 HWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVT
       :::.:.:::: ::::...: ::..::::.:::::.::::::.:::::::::::::.:: :
NP_001 HWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNNT
               40        50        60        70        80        90

         260       270       280       290       300       310     
pF1KB7 QMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAEITQLKI
       ::::::::::::::::::::..   :   . :.:. :::.::::::::::::..::::::
NP_001 QMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFIAVTAYQNTDITQLKI
              100       110       120       130       140       150

         320       330         340         350         360         
pF1KB7 DNNPFAKGFRENFESMYTSV--DTSIPSPP-GPNC-QFLGGDHYS--PLLPNQY--PVP-
       :.::::::::.:..::::.   :   :::  .:   :.. : .:.   ..:. .   .: 
NP_001 DHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYGVQSFFPEPFVNTLPQ
              160       170       180       190       200       210

        370                  380        390                400     
pF1KB7 SRFY------PDL-----PGQAKDVV-PQAYWLGAPRDH---------SYEAEFRAVSMK
       .:.:      :.      : :...:. :   :: .: ..         :::.:. . .. 
NP_001 ARYYNGERTVPQTNGLLSPQQSEEVANPPQRWLVTPVQQPGTNKLDISSYESEYTSSTLL
              220       230       240       250       260       270

         410          420       430       440        450       460 
pF1KB7 PAFLPSAPGPT---MSYYRGQEVLAPGAGWPVAPQYPPKMGPA-SWFRPMRTLPMEPGPG
       :  . : :  :   ..::  . ..   :::    .:  ::. .  :    :: :   .  
NP_001 PYGIKSLPLQTSHALGYY-PDPTFPAMAGWGGRGSYQRKMAAGLPWTS--RTSPTVFSED
              280        290       300       310         320       

              470       480         490       500       510        
pF1KB7 G-SEGRGPEDQGPPLVWTEIAP-IRP-ESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAP
         :. .  :. :    : :  : :.  .:.:::.  .  ::::.::  ::...:      
NP_001 QLSKEKVKEEIGSS--WIETPPSIKSLDSNDSGVYTSACKRRRLSPSNSSNENSPSIKCE
       330       340         350       360       370       380     

      520       530             
pF1KB7 SPFDKEAEGQFYNYFPN        
                                
NP_001 DINAEEYSKDTSKGMGGYYAFYTTP
         390       400       410

>>XP_011523797 (OMIM: 147891,601719) T-box transcription  (417 aa)
 initn: 692 init1: 268 opt: 716  Z-score: 448.2  bits: 92.3 E(92320): 3.4e-18
Smith-Waterman score: 731; 46.0% identity (67.8% similar) in 289 aa overlap (48-325:37-313)

        20        30        40        50         60        70      
pF1KB7 MPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGS-PYPGGALVPAPPSRFLGAYA
                                     ::  ...:  : :: :  :. :    :  .
XP_011 RLAPAPFYLLGCTWLVYFARSWESKSKPGMRRPLNKMGERPEPGDA--PGGP----GESG
         10        20        30        40        50              60

         80        90       100            110          120        
pF1KB7 YPPRPQAAGFPGAGESFPPPADAEGYQ-----PGEGYAAPDPRA---GLYPGPREDYALP
            :  :.  . :.:  :. : :       :  . :::   .   :  :::  : .  
XP_011 KKEMLQDKGLSESEEAFRAPGPALGEASAANAPEPALAAPGLSGAALGSPPGPGADVVAA
               70        80        90       100       110       120

      130        140       150       160       170       180       
pF1KB7 AGLEVSGK-LRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFV
       :. : . . ..:.:... ::.::..  ::::::: ::::::  .  :.:..: ..: ...
XP_011 AAAEQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLI
              130       140       150       160       170       180

       190       200       210       220       230       240       
pF1KB7 DVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNN
       :.: .:.:.... ..::.  :::: .::: ::::::::: :::::::: ::: :::::::
XP_011 DIVPADDHRYKFCDNKWMVAGKAEPAMPG-RLYVHPDSPATGAHWMRQLVSFQKLKLTNN
              190       200        210       220       230         

       250       260       270       280        290       300      
pF1KB7 KGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACN-ASNTHIFTFQETQFIAVTAYQ
       .    .    :.:.:.::::::::::......  .. : :  ::.:   ::.::.::.::
XP_011 HL---DPFGHIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVF--PETSFISVTSYQ
     240          250       260       270       280         290    

        310       320       330       340       350       360      
pF1KB7 NAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVP
       : .::::::.:::::::::                                         
XP_011 NHKITQLKIENNPFAKGFRGSDDSDLRVARLQSKEYPVISKSIMRQRLISPQLSATPDVG
          300       310       320       330       340       350    

>>XP_016884414 (OMIM: 187500,188400,192430,217095,602054  (545 aa)
 initn: 643 init1: 253 opt: 717  Z-score: 447.3  bits: 92.5 E(92320): 3.8e-18
Smith-Waterman score: 726; 33.1% identity (55.0% similar) in 522 aa overlap (27-517:45-539)

                   10        20        30        40        50      
pF1KB7     MGIVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGS
                                     ::. :   .:      ..:    . .:::.
XP_016 SIASLVAAEAAERTAHQGSGSSDRVKLRWLPGS-PAGMHFSTVTRDMEAFTASSLSSLGA
           20        30        40         50        60        70   

           60        70        80          90       100       110  
pF1KB7 P--YPGGALVPAPPSRFLGAYAYPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPD
          .::.:   : :         :::  : ::. :::  . :::  :  . :. : :.  
XP_016 AGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSA
            80        90       100       110        120       130  

            120       130          140       150       160         
pF1KB7 PRAGLYPGPREDYALPAGLEVSGKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPF
             ::     :  : .. ..:.    : :. . ::..:::  ::::.:: :::::: 
XP_016 AAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPT
            140       150       160       170       180       190  

     170       180       190         200       210       220       
pF1KB7 LSFTVAGLEPTSHYRMFVDVVLVDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPN
       ..  . :..: . : ...: : ::....::  .:..:.  :::. . :: :.. ::::: 
XP_016 FQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPA
            200       210       220       230       240        250 

       230       240       250       260       270       280       
pF1KB7 TGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNAS
        ::.::.: ::: :::::::   .:.    :.:.:.:.::::.:.: :.  .        
XP_016 KGAQWMKQIVSFDKLKLTNNLLDDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEE
             260       270          280       290       300        

       290       300       310       320       330       340       
pF1KB7 NTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNC
       : . :.:.::.: ::::::: .:::::: .::::::::.           . :    :. 
XP_016 NFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD-------CDPEDWPRNHRPGA
      310       320       330       340              350       360 

       350       360       370       380           390          400
pF1KB7 QFLGGDHYSPLLPNQYPVPSRFYPDLPGQAKDVVPQAYWL----GAPR---DHSYEAEFR
         :    .: .  .. :: :   :.  :  ::..     .    :.:    : ..  .. 
XP_016 LPL----MSAFARSRNPVASPTQPS--GTEKDAAEARREFQRDAGGPAVLGDPAHPPQLL
                 370       380         390       400       410     

                         410       420        430       440        
pF1KB7 AVSMKPAF-----------LPSAPGPTMSYYRGQEVL-APGAGWPVAPQYPPKMGPASWF
       :  ..:..           ::.:::   :    .  : ::::. :.  .. :   ::. .
XP_016 ARVLSPSLPGAGGAGGLVPLPGAPGGRPSPPNPELRLEAPGASEPL--HHHPYKYPAAAY
         420       430       440       450       460         470   

      450       460          470       480       490       500     
pF1KB7 RPMRTLPMEPGP---GGSEGRGPEDQGPPLVWTEIAPIRPESSDSGLGEGDSKRRRVSPY
         .     .:.:    : .:.: . .. :    .  :. : .. .. . . .    .. :
XP_016 DHYLGAKSRPAPYPLPGLRGHGYHPHAHP--HHHHHPVSPAAAAAAAAAAAAAA--ANMY
           480       490       500         510       520           

         510       520       530     
pF1KB7 PSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
        :.:  ..: :.                  
XP_016 SSAG--AAPPGSYDYCPR            
     530         540                 

>>NP_542378 (OMIM: 187500,188400,192430,217095,602054) T  (495 aa)
 initn: 643 init1: 253 opt: 716  Z-score: 447.2  bits: 92.3 E(92320): 3.9e-18
Smith-Waterman score: 725; 33.8% identity (54.8% similar) in 500 aa overlap (51-517:25-489)

               30        40        50        60            70      
pF1KB7 SDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG----GALVPAPPSRFLGAYA
                                     ::  :.  ::    :   : ::        
NP_542       MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP--------
                     10        20        30        40              

         80          90       100       110       120       130    
pF1KB7 YPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVS
        :::  : ::. :::  . :::  :  . :. : :.        ::     :  : .. .
NP_542 -PPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN
          50        60         70        80        90       100    

             140       150       160       170       180       190 
pF1KB7 GKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVL
       .:.    : :. . ::..:::  ::::.:: :::::: ..  . :..: . : ...: : 
NP_542 AKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVP
          110       120       130       140       150       160    

               200       210       220       230       240         
pF1KB7 VDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKG
       ::....::  .:..:.  :::. . :: :.. :::::  ::.::.: ::: :::::::  
NP_542 VDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLL
          170       180       190        200       210       220   

     250       260       270       280       290       300         
pF1KB7 ASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAE
        .:.    :.:.:.:.::::.:.: :.  .        : . :.:.::.: ::::::: .
NP_542 DDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
              230       240       250       260       270       280

     310       320       330       340       350       360         
pF1KB7 ITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRF
       :::::: .::::::::.           . :    :.   :    .: .  .. :: :  
NP_542 ITQLKIASNPFAKGFRD-------CDPEDWPRNHRPGALPL----MSAFARSRNPVASPT
              290              300       310           320         

     370       380           390          400                  410 
pF1KB7 YPDLPGQAKDVVPQAYWL----GAPR---DHSYEAEFRAVSMKPAF-----------LPS
        :.  :  ::..     .    :.:    : ..  .. :  ..:..           ::.
NP_542 QPS--GTEKDAAEARREFQRDAGGPAVLGDPAHPPQLLARVLSPSLPGAGGAGGLVPLPG
     330         340       350       360       370       380       

             420        430       440       450       460          
pF1KB7 APGPTMSYYRGQEVL-APGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGP---GGSEGRG
       :::   :    .  : ::::. :.  .. :   ::. .  .     .:.:    : .:.:
NP_542 APGGRPSPPNPELRLEAPGASEPL--HHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHG
       390       400       410         420       430       440     

       470       480       490       500       510       520       
pF1KB7 PEDQGPPLVWTEIAPIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEG
        . .. :    .  :. : .. .. . . .    .  : :.:  ..: :.          
NP_542 YHPHAHPH--HHHHPVSPAAAAAAAAAAAAAAANM--YSSAG--AAPPGSYDYCPR    
         450         460       470         480         490         

       530     
pF1KB7 QFYNYFPN

>>XP_016884415 (OMIM: 187500,188400,192430,217095,602054  (495 aa)
 initn: 643 init1: 253 opt: 716  Z-score: 447.2  bits: 92.3 E(92320): 3.9e-18
Smith-Waterman score: 725; 33.8% identity (54.8% similar) in 500 aa overlap (51-517:25-489)

               30        40        50        60            70      
pF1KB7 SDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG----GALVPAPPSRFLGAYA
                                     ::  :.  ::    :   : ::        
XP_016       MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPP--------
                     10        20        30        40              

         80          90       100       110       120       130    
pF1KB7 YPPR--PQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVS
        :::  : ::. :::  . :::  :  . :. : :.        ::     :  : .. .
XP_016 -PPRYDPCAAAAPGA-PGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKN
          50        60         70        80        90       100    

             140       150       160       170       180       190 
pF1KB7 GKL---RVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVL
       .:.    : :. . ::..:::  ::::.:: :::::: ..  . :..: . : ...: : 
XP_016 AKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVP
          110       120       130       140       150       160    

               200       210       220       230       240         
pF1KB7 VDQHHWRY--QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKG
       ::....::  .:..:.  :::. . :: :.. :::::  ::.::.: ::: :::::::  
XP_016 VDDKRYRYAFHSSSWLVAGKADPATPG-RVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLL
          170       180       190        200       210       220   

     250       260       270       280       290       300         
pF1KB7 ASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFIAVTAYQNAE
        .:.    :.:.:.:.::::.:.: :.  .        : . :.:.::.: ::::::: .
XP_016 DDNG---HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHR
              230       240       250       260       270       280

     310       320       330       340       350       360         
pF1KB7 ITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRF
       :::::: .::::::::.           . :    :.   :    .: .  .. :: :  
XP_016 ITQLKIASNPFAKGFRD-------CDPEDWPRNHRPGALPL----MSAFARSRNPVASPT
              290              300       310           320         

     370       380           390          400                  410 
pF1KB7 YPDLPGQAKDVVPQAYWL----GAPR---DHSYEAEFRAVSMKPAF-----------LPS
        :.  :  ::..     .    :.:    : ..  .. :  ..:..           ::.
XP_016 QPS--GTEKDAAEARREFQRDAGGPAVLGDPAHPPQLLARVLSPSLPGAGGAGGLVPLPG
     330         340       350       360       370       380       

             420        430       440       450       460          
pF1KB7 APGPTMSYYRGQEVL-APGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGP---GGSEGRG
       :::   :    .  : ::::. :.  .. :   ::. .  .     .:.:    : .:.:
XP_016 APGGRPSPPNPELRLEAPGASEPL--HHHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHG
       390       400       410         420       430       440     

       470       480       490       500       510       520       
pF1KB7 PEDQGPPLVWTEIAPIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEG
        . .. :    .  :. : .. .. . . .    .  : :.:  ..: :.          
XP_016 YHPHAHPH--HHHHPVSPAAAAAAAAAAAAAAANM--YSSAG--AAPPGSYDYCPR    
         450         460       470         480         490         

       530     
pF1KB7 QFYNYFPN




535 residues in 1 query   sequences
64369986 residues in 92320 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:47:18 2019 done: Thu Oct 24 21:47:19 2019
 Total Scan time:  5.510 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
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