Result of FASTA (omim) for pF1KB6562
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6562, 399 aa
  1>>>pF1KB6562     399 - 399 aa - 399 aa
Library: /omim/omim.rfq.tfa
  64369986 residues in 92320 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.1703+/-0.000491; mu= -8.9896+/- 0.030
 mean_var=644.0176+/-142.783, 0's: 0 Z-trim(121.3): 1289  B-trim: 0 in 0/54
 Lambda= 0.050539
 statistics sampled from 37138 (39180) to 37138 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.424), width:  16
 Scan time:  4.560

The best scores are:                                      opt bits E(92320)
NP_003001 (OMIM: 601335) dual specificity mitogen- ( 399) 2710 212.7 1.4e-54
NP_001268364 (OMIM: 601335) dual specificity mitog ( 410) 2479 195.9 1.6e-49
XP_005256810 (OMIM: 601335) dual specificity mitog ( 281) 1899 153.4   7e-37
XP_011522278 (OMIM: 601335) dual specificity mitog ( 319) 1776 144.5 3.8e-34
XP_005256812 (OMIM: 601335) dual specificity mitog ( 253) 1723 140.5 4.8e-33
XP_011522279 (OMIM: 601335) dual specificity mitog ( 253) 1723 140.5 4.8e-33
NP_002749 (OMIM: 601254) dual specificity mitogen- ( 334) 1200 102.5 1.7e-21
XP_011523328 (OMIM: 601254) dual specificity mitog ( 337) 1200 102.5 1.7e-21
XP_006722038 (OMIM: 601254) dual specificity mitog ( 278) 1166 99.9 8.6e-21
NP_001317379 (OMIM: 601254) dual specificity mitog ( 278) 1166 99.9 8.6e-21
XP_005257573 (OMIM: 601254) dual specificity mitog ( 278) 1166 99.9 8.6e-21
XP_011523329 (OMIM: 601254) dual specificity mitog ( 278) 1166 99.9 8.6e-21
XP_016880348 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
NP_002747 (OMIM: 602315) dual specificity mitogen- ( 318) 1147 98.6 2.4e-20
XP_011522261 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
NP_001303261 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
XP_005256780 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
XP_016880347 (OMIM: 602315) dual specificity mitog ( 318) 1147 98.6 2.4e-20
XP_016880346 (OMIM: 602315) dual specificity mitog ( 343) 1147 98.7 2.5e-20
NP_659731 (OMIM: 602315) dual specificity mitogen- ( 347) 1147 98.7 2.5e-20
NP_001284484 (OMIM: 603014) dual specificity mitog ( 435) 1000 88.1 4.9e-17
NP_660186 (OMIM: 603014) dual specificity mitogen- ( 419)  995 87.7 6.1e-17
XP_006722863 (OMIM: 603014) dual specificity mitog ( 442)  976 86.4 1.6e-16
NP_001284485 (OMIM: 603014) dual specificity mitog ( 426)  971 86.0 2.1e-16
XP_011522260 (OMIM: 602315) dual specificity mitog ( 298)  907 81.1 4.3e-15
XP_011520085 (OMIM: 163950,176872,615279) dual spe ( 371)  612 59.7 1.5e-08
NP_002746 (OMIM: 163950,176872,615279) dual specif ( 393)  612 59.7 1.5e-08
NP_109587 (OMIM: 601263,615280) dual specificity m ( 400)  612 59.8 1.5e-08
XP_016882478 (OMIM: 601263,615280) dual specificit ( 512)  612 59.9 1.7e-08
XP_024305756 (OMIM: 602520) dual specificity mitog ( 371)  553 55.4 2.9e-07
NP_001193733 (OMIM: 602520) dual specificity mitog ( 412)  553 55.5   3e-07
NP_660143 (OMIM: 602520) dual specificity mitogen- ( 448)  553 55.5 3.2e-07
XP_016869247 (OMIM: 605030) serine/threonine-prote ( 456)  552 55.5 3.4e-07
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519)  553 55.6 3.5e-07
XP_016869246 (OMIM: 605030) serine/threonine-prote ( 524)  553 55.6 3.5e-07
NP_006272 (OMIM: 605030) serine/threonine-protein  ( 491)  552 55.5 3.5e-07
XP_011515553 (OMIM: 605030) serine/threonine-prote ( 522)  552 55.5 3.7e-07
XP_011515550 (OMIM: 605030) serine/threonine-prote ( 576)  553 55.7 3.7e-07
XP_016869245 (OMIM: 605030) serine/threonine-prote ( 580)  553 55.7 3.7e-07
XP_016883522 (OMIM: 604965,614868) serine/threonin ( 388)  545 54.8 4.4e-07
XP_011527322 (OMIM: 604965,614868) serine/threonin ( 404)  545 54.9 4.5e-07
NP_001339314 (OMIM: 604965,614868) serine/threonin ( 462)  545 55.0 4.9e-07
XP_005260588 (OMIM: 604965,614868) serine/threonin ( 478)  545 55.0   5e-07
NP_006273 (OMIM: 604965,614868) serine/threonine-p ( 487)  545 55.0   5e-07
XP_005260587 (OMIM: 604965,614868) serine/threonin ( 503)  545 55.0 5.1e-07
XP_016883521 (OMIM: 604965,614868) serine/threonin ( 458)  521 53.2 1.6e-06
XP_016883518 (OMIM: 604965,614868) serine/threonin ( 474)  521 53.2 1.7e-06
XP_016883519 (OMIM: 604965,614868) serine/threonin ( 474)  521 53.2 1.7e-06
XP_005260589 (OMIM: 604965,614868) serine/threonin ( 474)  521 53.2 1.7e-06
XP_016883520 (OMIM: 604965,614868) serine/threonin ( 474)  521 53.2 1.7e-06


>>NP_003001 (OMIM: 601335) dual specificity mitogen-acti  (399 aa)
 initn: 2710 init1: 2710 opt: 2710  Z-score: 1101.7  bits: 212.7 E(92320): 1.4e-54
Smith-Waterman score: 2710; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399)

               10        20        30        40        50        60
pF1KB6 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 HKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMEL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 MSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 ATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKE
              310       320       330       340       350       360

              370       380       390         
pF1KB6 LLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
       :::::::::::::::::::::::::::::::::::::::
NP_003 LLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
              370       380       390         

>>NP_001268364 (OMIM: 601335) dual specificity mitogen-a  (410 aa)
 initn: 2437 init1: 2437 opt: 2479  Z-score: 1010.6  bits: 195.9 E(92320): 1.6e-49
Smith-Waterman score: 2678; 97.3% identity (97.3% similar) in 410 aa overlap (1-399:1-410)

               10        20        30                   40         
pF1KB6 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQG-----------KRKALKLNFA
       :::::::::::::::::::::::::::::::::::::::           ::::::::::
NP_001 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KB6 NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
               70        80        90       100       110       120

     110       120       130       140       150       160         
pF1KB6 RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
              130       140       150       160       170       180

     170       180       190       200       210       220         
pF1KB6 REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
              190       200       210       220       230       240

     230       240       250       260       270       280         
pF1KB6 IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KB6 VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
              310       320       330       340       350       360

     350       360       370       380       390         
pF1KB6 KDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
              370       380       390       400       410

>>XP_005256810 (OMIM: 601335) dual specificity mitogen-a  (281 aa)
 initn: 1899 init1: 1899 opt: 1899  Z-score: 783.7  bits: 153.4 E(92320): 7e-37
Smith-Waterman score: 1899; 100.0% identity (100.0% similar) in 281 aa overlap (119-399:1-281)

       90       100       110       120       130       140        
pF1KB6 ISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMD
                                     ::::::::::::::::::::::::::::::
XP_005                               MVHKPSGQIMAVKRIRSTVDEKEQKQLLMD
                                             10        20        30

      150       160       170       180       190       200        
pF1KB6 LDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKI
               40        50        60        70        80        90

      210       220       230       240       250       260        
pF1KB6 TLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRP
              100       110       120       130       140       150

      270       280       290       300       310       320        
pF1KB6 YMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQL
              160       170       180       190       200       210

      330       340       350       360       370       380        
pF1KB6 SNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQM
              220       230       240       250       260       270

      390         
pF1KB6 PATPSSPMYVD
       :::::::::::
XP_005 PATPSSPMYVD
              280 

>>XP_011522278 (OMIM: 601335) dual specificity mitogen-a  (319 aa)
 initn: 1734 init1: 1734 opt: 1776  Z-score: 734.7  bits: 144.5 E(92320): 3.8e-34
Smith-Waterman score: 1975; 96.4% identity (96.4% similar) in 308 aa overlap (1-297:1-308)

               10        20        30                   40         
pF1KB6 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQG-----------KRKALKLNFA
       :::::::::::::::::::::::::::::::::::::::           ::::::::::
XP_011 MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KB6 NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
               70        80        90       100       110       120

     110       120       130       140       150       160         
pF1KB6 RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
              130       140       150       160       170       180

     170       180       190       200       210       220         
pF1KB6 REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
              190       200       210       220       230       240

     230       240       250       260       270       280         
pF1KB6 IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KB6 VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
       ::::::::                                                    
XP_011 VWSLGITLIIGVNYYLQLH                                         
              310                                                  

>>XP_005256812 (OMIM: 601335) dual specificity mitogen-a  (253 aa)
 initn: 1723 init1: 1723 opt: 1723  Z-score: 714.8  bits: 140.5 E(92320): 4.8e-33
Smith-Waterman score: 1723; 100.0% identity (100.0% similar) in 253 aa overlap (147-399:1-253)

        120       130       140       150       160       170      
pF1KB6 NKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWI
                                     ::::::::::::::::::::::::::::::
XP_005                               MDLDVVMRSSDCPYIVQFYGALFREGDCWI
                                             10        20        30

        180       190       200       210       220       230      
pF1KB6 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
               40        50        60        70        80        90

        240       250       260       270       280       290      
pF1KB6 LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
              100       110       120       130       140       150

        300       310       320       330       340       350      
pF1KB6 LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
              160       170       180       190       200       210

        360       370       380       390         
pF1KB6 KYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
       :::::::::::::::::::::::::::::::::::::::::::
XP_005 KYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
              220       230       240       250   

>>XP_011522279 (OMIM: 601335) dual specificity mitogen-a  (253 aa)
 initn: 1723 init1: 1723 opt: 1723  Z-score: 714.8  bits: 140.5 E(92320): 4.8e-33
Smith-Waterman score: 1723; 100.0% identity (100.0% similar) in 253 aa overlap (147-399:1-253)

        120       130       140       150       160       170      
pF1KB6 NKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWI
                                     ::::::::::::::::::::::::::::::
XP_011                               MDLDVVMRSSDCPYIVQFYGALFREGDCWI
                                             10        20        30

        180       190       200       210       220       230      
pF1KB6 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNIL
               40        50        60        70        80        90

        240       250       260       270       280       290      
pF1KB6 LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGIT
              100       110       120       130       140       150

        300       310       320       330       340       350      
pF1KB6 LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRP
              160       170       180       190       200       210

        360       370       380       390         
pF1KB6 KYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
       :::::::::::::::::::::::::::::::::::::::::::
XP_011 KYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
              220       230       240       250   

>>NP_002749 (OMIM: 601254) dual specificity mitogen-acti  (334 aa)
 initn: 1201 init1: 586 opt: 1200  Z-score: 507.5  bits: 102.5 E(92320): 1.7e-21
Smith-Waterman score: 1200; 54.9% identity (81.1% similar) in 317 aa overlap (69-385:21-332)

       40        50        60        70        80        90        
pF1KB6 GKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFT
                                     ..:.      ....:.. ..:. .:...  
NP_002           MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIG-NQNFEVK
                         10        20        30        40          

      100       110       120       130       140       150        
pF1KB6 AEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDC
       :.::. . :.:::::: :.:: : ::::::::::::.::. .:::.::::::. ::. ::
NP_002 ADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDC
      50        60        70        80        90       100         

      160       170       180       190       200       210        
pF1KB6 PYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNH
       :. : :::::::::: :::::::.::.::::: : .   ..:::.:::::... ::::.:
NP_002 PFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-GQTIPEDILGKIAVSIVKALEH
     110       120       130       140        150       160        

      220       230       240       250       260       270        
pF1KB6 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPS
       :. .:..::::.::::.:..  :..:.::::::: ::::.::: ::::.::::::::.: 
NP_002 LHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPE
      170       180       190       200       210       220        

      280       290       300       310       320       330        
pF1KB6 ASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSP
        ...::.:.::.::::::. :::  :::: .:.. :.:: :::.   :::  ..   :: 
NP_002 LNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADK---FSA
      230       240       250       260       270       280        

      340       350       360       370       380       390        
pF1KB6 SFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYV
        :..:.. :: :. ..:: : ::..:::. ..: ....:: .:  ::             
NP_002 EFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD           
         290       300       310       320       330               

        
pF1KB6 D

>>XP_011523328 (OMIM: 601254) dual specificity mitogen-a  (337 aa)
 initn: 1201 init1: 586 opt: 1200  Z-score: 507.5  bits: 102.5 E(92320): 1.7e-21
Smith-Waterman score: 1200; 54.9% identity (81.1% similar) in 317 aa overlap (69-385:24-335)

       40        50        60        70        80        90        
pF1KB6 GKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFT
                                     ..:.      ....:.. ..:. .:...  
XP_011        MSHRAWAEGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIG-NQNFEVK
                      10        20        30        40         50  

      100       110       120       130       140       150        
pF1KB6 AEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDC
       :.::. . :.:::::: :.:: : ::::::::::::.::. .:::.::::::. ::. ::
XP_011 ADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDC
             60        70        80        90       100       110  

      160       170       180       190       200       210        
pF1KB6 PYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNH
       :. : :::::::::: :::::::.::.::::: : .   ..:::.:::::... ::::.:
XP_011 PFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-GQTIPEDILGKIAVSIVKALEH
            120       130       140        150       160       170 

      220       230       240       250       260       270        
pF1KB6 LKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPS
       :. .:..::::.::::.:..  :..:.::::::: ::::.::: ::::.::::::::.: 
XP_011 LHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPE
             180       190       200       210       220       230 

      280       290       300       310       320       330        
pF1KB6 ASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSP
        ...::.:.::.::::::. :::  :::: .:.. :.:: :::.   :::  ..   :: 
XP_011 LNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADK---FSA
             240       250       260       270       280           

      340       350       360       370       380       390        
pF1KB6 SFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYV
        :..:.. :: :. ..:: : ::..:::. ..: ....:: .:  ::             
XP_011 EFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD           
      290       300       310       320       330                  

        
pF1KB6 D

>>XP_006722038 (OMIM: 601254) dual specificity mitogen-a  (278 aa)
 initn: 1173 init1: 586 opt: 1166  Z-score: 494.9  bits: 99.9 E(92320): 8.6e-21
Smith-Waterman score: 1166; 59.9% identity (82.8% similar) in 279 aa overlap (107-385:2-276)

         80        90       100       110       120       130      
pF1KB6 RTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRST
                                     :.:::::: :.:: : ::::::::::::.:
XP_006                              MELGRGAYGVVEKMRHVPSGQIMAVKRIRAT
                                            10        20        30 

        140       150       160       170       180       190      
pF1KB6 VDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVL
       :. .:::.::::::. ::. :::. : :::::::::: :::::::.::.::::: : .  
XP_006 VNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-
              40        50        60        70        80        90 

        200       210       220       230       240       250      
pF1KB6 DDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVD
        ..:::.:::::... ::::.::. .:..::::.::::.:..  :..:.::::::: :::
XP_006 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
              100       110       120       130       140       150

        260       270       280       290       300       310      
pF1KB6 SIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQ
       :.::: ::::.::::::::.:  ...::.:.::.::::::. :::  :::: .:.. :.:
XP_006 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
              160       170       180       190       200       210

        320       330       340       350       360       370      
pF1KB6 LTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVE
       : :::.   :::  ..   ::  :..:.. :: :. ..:: : ::..:::. ..: ....
XP_006 LKQVVEEPSPQLPADK---FSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTD
              220          230       240       250       260       

        380       390         
pF1KB6 VACYVCKILDQMPATPSSPMYVD
       :: .:  ::              
XP_006 VASFVKLILGD            
       270                    

>>NP_001317379 (OMIM: 601254) dual specificity mitogen-a  (278 aa)
 initn: 1173 init1: 586 opt: 1166  Z-score: 494.9  bits: 99.9 E(92320): 8.6e-21
Smith-Waterman score: 1166; 59.9% identity (82.8% similar) in 279 aa overlap (107-385:2-276)

         80        90       100       110       120       130      
pF1KB6 RTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRST
                                     :.:::::: :.:: : ::::::::::::.:
NP_001                              MELGRGAYGVVEKMRHVPSGQIMAVKRIRAT
                                            10        20        30 

        140       150       160       170       180       190      
pF1KB6 VDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVL
       :. .:::.::::::. ::. :::. : :::::::::: :::::::.::.::::: : .  
NP_001 VNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK-
              40        50        60        70        80        90 

        200       210       220       230       240       250      
pF1KB6 DDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVD
        ..:::.:::::... ::::.::. .:..::::.::::.:..  :..:.::::::: :::
NP_001 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
              100       110       120       130       140       150

        260       270       280       290       300       310      
pF1KB6 SIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQ
       :.::: ::::.::::::::.:  ...::.:.::.::::::. :::  :::: .:.. :.:
NP_001 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
              160       170       180       190       200       210

        320       330       340       350       360       370      
pF1KB6 LTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVE
       : :::.   :::  ..   ::  :..:.. :: :. ..:: : ::..:::. ..: ....
NP_001 LKQVVEEPSPQLPADK---FSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTD
              220          230       240       250       260       

        380       390         
pF1KB6 VACYVCKILDQMPATPSSPMYVD
       :: .:  ::              
NP_001 VASFVKLILGD            
       270                    




399 residues in 1 query   sequences
64369986 residues in 92320 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:46:21 2019 done: Thu Oct 24 21:46:22 2019
 Total Scan time:  4.560 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com