Result of FASTA (ccds) for pF1KB5924
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5924, 520 aa
  1>>>pF1KB5924 520 - 520 aa - 520 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9969+/-0.000941; mu= 14.1488+/- 0.056
 mean_var=64.3924+/-12.828, 0's: 0 Z-trim(104.2): 20  B-trim: 5 in 1/49
 Lambda= 0.159829
 statistics sampled from 7767 (7772) to 7767 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.239), width:  16
 Scan time:  3.350

The best scores are:                                      opt bits E(32554)
CCDS9109.2 RIC8B gene_id:55188|Hs108|chr12         ( 520) 3369 785.9       0
CCDS81733.1 RIC8B gene_id:55188|Hs108|chr12        ( 536) 3145 734.2 8.6e-212
CCDS81734.1 RIC8B gene_id:55188|Hs108|chr12        ( 560) 3145 734.2  9e-212
CCDS65982.1 RIC8A gene_id:60626|Hs108|chr11        ( 531)  671 163.8 4.5e-40
CCDS7690.1 RIC8A gene_id:60626|Hs108|chr11         ( 537)  650 158.9 1.3e-38


>>CCDS9109.2 RIC8B gene_id:55188|Hs108|chr12              (520 aa)
 initn: 3369 init1: 3369 opt: 3369  Z-score: 4195.2  bits: 785.9 E(32554):    0
Smith-Waterman score: 3369; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)

               10        20        30        40        50        60
pF1KB5 MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 TCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 TCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 LCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 QLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 QLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 SWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 SWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 THEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 THEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 EGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 EGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 KQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 KQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKN
              430       440       450       460       470       480

              490       500       510       520
pF1KB5 AKPKEELLKPMGLKPDGTITPLEEALNQYSVIEETSSDTD
       ::::::::::::::::::::::::::::::::::::::::
CCDS91 AKPKEELLKPMGLKPDGTITPLEEALNQYSVIEETSSDTD
              490       500       510       520

>>CCDS81733.1 RIC8B gene_id:55188|Hs108|chr12             (536 aa)
 initn: 3165 init1: 3139 opt: 3145  Z-score: 3915.8  bits: 734.2 E(32554): 8.6e-212
Smith-Waterman score: 3145; 94.9% identity (97.1% similar) in 514 aa overlap (1-513:1-514)

               10        20        30        40        50        60
pF1KB5 MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 TCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 QLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 SWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 THEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 THEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 EGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 EGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 KQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKN
              430       440       450       460       470       480

              490        500       510       520               
pF1KB5 AKPKEELLKPMGLKP-DGTITPLEEALNQYSVIEETSSDTD               
       :::. .:.     .:  . :  . :  ..: ...                      
CCDS81 AKPNINLITGHLEEPMPNPIDEMTEEQKEYEAMKLVNMLDKLSRRADVKDLHQDGG
              490       500       510       520       530      

>>CCDS81734.1 RIC8B gene_id:55188|Hs108|chr12             (560 aa)
 initn: 3381 init1: 3139 opt: 3145  Z-score: 3915.5  bits: 734.2 E(32554): 9e-212
Smith-Waterman score: 3228; 92.6% identity (92.8% similar) in 552 aa overlap (1-512:1-552)

               10        20        30        40        50        60
pF1KB5 MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MDEERALYIVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 TCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLKC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 QLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 QLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 SWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 THEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 THEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 EGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 EGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 KQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKN
              430       440       450       460       470       480

                                                      490       500
pF1KB5 AKP----------------------------------------KEELLKPMGLKPDGTIT
       :::                                        .::::::::::::::::
CCDS81 AKPNINLITGHLEEPMPNPIDEMTEEQKEYEAMKLVNMLDKLSREELLKPMGLKPDGTIT
              490       500       510       520       530       540

              510       520
pF1KB5 PLEEALNQYSVIEETSSDTD
       ::::::::::::        
CCDS81 PLEEALNQYSVIEETSSDTD
              550       560

>>CCDS65982.1 RIC8A gene_id:60626|Hs108|chr11             (531 aa)
 initn: 1338 init1: 671 opt: 671  Z-score: 832.8  bits: 163.8 E(32554): 4.5e-40
Smith-Waterman score: 1316; 47.3% identity (73.3% similar) in 484 aa overlap (3-482:2-450)

                10        20        30        40        50         
pF1KB5 MDEERALY-IVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIP
         : ::.   :..::  .: ..::.:...:  .: :...... ::.: : . .:: . .:
CCDS65  MEPRAVAEAVETGEEDVIMEALRSYNQEHSQSFTFDDAQQEDRKRLAELLVSVLEQGLP
                10        20        30        40        50         

      60        70        80        90       100       110         
pF1KB5 TTCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLK
        . .:  :. .::::::.. : : :.....: :   : ..  . :. . ... :..::::
CCDS65 PSHRVIWLQSVRILSRDRNCLDPFTSRQSLQALACYADISVSEGSVPESADMDVVLESLK
      60        70        80        90       100       110         

     120       130       140       150       160       170         
pF1KB5 CLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIR
       ::::.:..: .::.:. :  :..:: . .   ..:.: .:.. :::::::::. :.::.:
CCDS65 CLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLLTALRTDVR
     120       130       140       150       160       170         

     180       190       200       210         220       230       
pF1KB5 SQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPP--LSPQETDCAIEALKALFNV
       .::  ::.:. :::. :: ....  : :       : ::  :  :::. :.: ::.:::.
CCDS65 QQLFQELKGVRLLTDTLELTLGV--TPE------GNPPPTLLPSQETERAMEILKVLFNI
     180       190       200               210       220       230 

       240        250       260       270       280       290      
pF1KB5 TVDSWKVH-KESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVL
       :.:: : .  : :.  .: ....::::..:.  . :.:::.:..:::::.:.:..:::::
CCDS65 TLDSIKGEVDEEDAALYRHLGTLLRHCVMIA-TAGDRTEEFHGHAVNLLGNLPLKCLDVL
             240       250       260        270       280       290

        300       310       320       330       340       350      
pF1KB5 ICPLTHEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKG
       .             ::.  : . ..:           . :.::..:..:: :.:::. : 
CCDS65 L-------------TLE--PHGDSTE-----------FMGVNMDVIRALLIFLEKRLHKT
                             300                  310       320    

        360       370       380       390       400       410      
pF1KB5 SSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHV
          .:...::::.::::.: ::  ::::: ::::::::: .:::::  .::::::::::.
CCDS65 HRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHL
          330       340       350       360       370       380    

        420       430       440       450       460       470      
pF1KB5 DLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTE
       :  ::..:::::::::.: :  ..:::::::::::::::::.:::: .. :::::::::.
CCDS65 DTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTD
          390       400       410       420       430       440    

        480       490       500       510       520                
pF1KB5 EYKNAKPKEELLKPMGLKPDGTITPLEEALNQYSVIEETSSDTD                
       :::.::                                                      
CCDS65 EYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPR
          450       460       470       480       490       500    

>>CCDS7690.1 RIC8A gene_id:60626|Hs108|chr11              (537 aa)
 initn: 1128 init1: 484 opt: 650  Z-score: 806.6  bits: 158.9 E(32554): 1.3e-38
Smith-Waterman score: 1295; 46.7% identity (72.4% similar) in 490 aa overlap (3-482:2-456)

                10        20        30        40        50         
pF1KB5 MDEERALY-IVRAGEAGAIERVLRDYSDKHRATFKFESTDEDKRKKLCEGIFKVLIKDIP
         : ::.   :..::  .: ..::.:...:  .: :...... ::.: : . .:: . .:
CCDS76  MEPRAVAEAVETGEEDVIMEALRSYNQEHSQSFTFDDAQQEDRKRLAELLVSVLEQGLP
                10        20        30        40        50         

      60        70        80        90       100       110         
pF1KB5 TTCQVSCLEVLRILSRDKKVLVPVTTKENMQILLRLAKLNELDDSLEKVSEFPVIVESLK
        . .:  :. .::::::.. : : :.....: :   : ..  . :. . ... :..::::
CCDS76 PSHRVIWLQSVRILSRDRNCLDPFTSRQSLQALACYADISVSEGSVPESADMDVVLESLK
      60        70        80        90       100       110         

     120       130       140       150       160       170         
pF1KB5 CLCNIVFNSQMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIR
       ::::.:..: .::.:. :  :..:: . .   ..:.: .:.. :::::::::. :.::.:
CCDS76 CLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLLTALRTDVR
     120       130       140       150       160       170         

     180       190       200       210         220       230       
pF1KB5 SQLRYELQGLPLLTQILESAFSIKWTDEYESAIDHNGPP--LSPQETDCAIEALKALFNV
       .::  ::.:. :::. :: ....  : :       : ::  :  :::. :.: ::.:::.
CCDS76 QQLFQELKGVRLLTDTLELTLGV--TPE------GNPPPTLLPSQETERAMEILKVLFNI
     180       190       200               210       220       230 

       240        250       260       270       280       290      
pF1KB5 TVDSWKVH-KESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVL
       :.:: : .  : :.  .: ....::::..:.  . :.:::.:..:::::.:.:..:::::
CCDS76 TLDSIKGEVDEEDAALYRHLGTLLRHCVMIA-TAGDRTEEFHGHAVNLLGNLPLKCLDVL
             240       250       260        270       280       290

        300       310       320       330       340       350      
pF1KB5 ICPLTHEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKG
       .             ::.  : . ..:           . :.::..:..:: :.:::. : 
CCDS76 L-------------TLE--PHGDSTE-----------FMGVNMDVIRALLIFLEKRLHKT
                             300                  310       320    

        360       370       380             390       400       410
pF1KB5 SSYREGLTPVLSLLTECSRAHRNIRKFLK------DQVLPPLRDVTNRPEVGSTVRNKLV
          .:...::::.::::.: ::  :::::       ::::::::: .:::::  .:::::
CCDS76 HRLKESVAPVLSVLTECARMHRPARKFLKAQGWPPPQVLPPLRDVRTRPEVGEMLRNKLV
          330       340       350       360       370       380    

              420       430       440       450       460       470
pF1KB5 RLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSED
       :::::.:  ::..:::::::::.: :  ..:::::::::::::::::.:::: .. ::::
CCDS76 RLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSED
          390       400       410       420       430       440    

              480       490       500       510       520          
pF1KB5 EDTDTEEYKNAKPKEELLKPMGLKPDGTITPLEEALNQYSVIEETSSDTD          
       :::::.:::.::                                                
CCDS76 EDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQP
          450       460       470       480       490       500    




520 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 04:48:23 2016 done: Mon Nov  7 04:48:23 2016
 Total Scan time:  3.350 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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