Result of FASTA (omim) for
pF1KE2406
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2406, 1497 aa
1>>>pF1KE2406 1497 - 1497 aa - 1497 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.1036+/-0.000567; mu= -29.6993+/- 0.036
mean_var=885.2775+/-182.864, 0's: 0 Z-trim(123.0): 627 B-trim: 0 in 0/62
Lambda= 0.043106
statistics sampled from 41284 (42009) to 41284 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.493), width: 16
Scan time: 23.790
The best scores are: opt bits E(85289)
NP_000485 (OMIM: 113811,122400,226650) collagen al (1497) 10430 665.6 8e-190
NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418) 1708 123.2 1.5e-26
XP_016874319 (OMIM: 108300,120140,132450,150600,15 (1465) 1708 123.2 1.5e-26
NP_001835 (OMIM: 108300,120140,132450,150600,15121 (1487) 1708 123.2 1.5e-26
XP_016874318 (OMIM: 108300,120140,132450,150600,15 (1534) 1708 123.2 1.6e-26
XP_016874317 (OMIM: 108300,120140,132450,150600,15 (1535) 1708 123.2 1.6e-26
XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 1681 121.5 4.4e-26
NP_690848 (OMIM: 610026) collagen alpha-1(XXII) ch (1626) 1603 116.7 1.5e-24
XP_011515189 (OMIM: 610026) PREDICTED: collagen al (1264) 1543 112.9 1.7e-23
XP_016868641 (OMIM: 610026) PREDICTED: collagen al (1264) 1543 112.9 1.7e-23
XP_016868639 (OMIM: 610026) PREDICTED: collagen al (1564) 1543 113.0 1.9e-23
XP_011515188 (OMIM: 610026) PREDICTED: collagen al (1577) 1543 113.0 1.9e-23
XP_011515185 (OMIM: 610026) PREDICTED: collagen al (1606) 1543 113.0 2e-23
XP_011515187 (OMIM: 610026) PREDICTED: collagen al (1588) 1538 112.7 2.4e-23
XP_011515186 (OMIM: 610026) PREDICTED: collagen al (1593) 1537 112.6 2.5e-23
NP_000081 (OMIM: 120180,130020,130050) collagen al (1466) 1533 112.3 2.8e-23
XP_011515191 (OMIM: 610026) PREDICTED: collagen al (1058) 1523 111.6 3.4e-23
XP_005246337 (OMIM: 104200,120070,141200,203780) P (1051) 1489 109.5 1.5e-22
XP_016858784 (OMIM: 104200,120070,141200,203780) P (1119) 1489 109.5 1.5e-22
XP_006712308 (OMIM: 104200,120070,141200,203780) P (1189) 1489 109.5 1.6e-22
XP_011508857 (OMIM: 104200,120070,141200,203780) P (1609) 1489 109.6 2e-22
NP_000082 (OMIM: 104200,120070,141200,203780) coll (1670) 1489 109.7 2.1e-22
XP_016865740 (OMIM: 120290,184840,215150,277610,60 (1342) 1461 107.8 5.9e-22
XP_011512604 (OMIM: 120290,184840,215150,277610,60 (1365) 1461 107.8 6e-22
XP_011512602 (OMIM: 120290,184840,215150,277610,60 (1438) 1461 107.9 6.2e-22
XP_011512601 (OMIM: 120290,184840,215150,277610,60 (1498) 1461 107.9 6.4e-22
NP_542410 (OMIM: 120290,184840,215150,277610,60186 (1629) 1461 107.9 6.8e-22
NP_542412 (OMIM: 120290,184840,215150,277610,60186 (1650) 1461 107.9 6.9e-22
NP_542411 (OMIM: 120290,184840,215150,277610,60186 (1736) 1461 107.9 7.2e-22
XP_016865739 (OMIM: 120290,184840,215150,277610,60 (1736) 1461 107.9 7.2e-22
XP_016884751 (OMIM: 301050,303630) PREDICTED: coll (1289) 1441 106.6 1.4e-21
XP_016884750 (OMIM: 301050,303630) PREDICTED: coll (1330) 1441 106.6 1.4e-21
XP_011508859 (OMIM: 120131,203780) PREDICTED: coll (1663) 1425 105.7 3.3e-21
XP_011508875 (OMIM: 120190,130000) PREDICTED: coll (1453) 1410 104.7 5.7e-21
NP_000384 (OMIM: 120190,130000) collagen alpha-2(V (1499) 1410 104.7 5.8e-21
XP_005246334 (OMIM: 104200,120070,141200,203780) P (1635) 1408 104.6 6.7e-21
XP_005257115 (OMIM: 114000,120150,130000,130060,16 (1374) 1405 104.4 6.7e-21
NP_378667 (OMIM: 300914,303631) collagen alpha-6(I (1690) 1402 104.3 8.9e-21
NP_001838 (OMIM: 300914,303631) collagen alpha-6(I (1691) 1402 104.3 8.9e-21
XP_011529155 (OMIM: 300914,303631) PREDICTED: coll (1680) 1398 104.0 1.1e-20
NP_001274687 (OMIM: 300914,303631) collagen alpha- (1707) 1398 104.0 1.1e-20
XP_006724680 (OMIM: 300914,303631) PREDICTED: coll (1708) 1398 104.0 1.1e-20
NP_000080 (OMIM: 120160,130060,166210,166220,16671 (1366) 1378 102.7 2.1e-20
XP_016858786 (OMIM: 120131,203780) PREDICTED: coll (1651) 1371 102.3 3.3e-20
XP_011508874 (OMIM: 120131,203780) PREDICTED: coll (1132) 1362 101.6 3.7e-20
XP_005246339 (OMIM: 120131,203780) PREDICTED: coll (1505) 1362 101.7 4.6e-20
XP_016858788 (OMIM: 120131,203780) PREDICTED: coll (1518) 1362 101.7 4.6e-20
XP_011508863 (OMIM: 120131,203780) PREDICTED: coll (1608) 1362 101.7 4.8e-20
XP_011508864 (OMIM: 120131,203780) PREDICTED: coll (1608) 1362 101.7 4.8e-20
XP_016858787 (OMIM: 120131,203780) PREDICTED: coll (1608) 1362 101.7 4.8e-20
>>NP_000485 (OMIM: 113811,122400,226650) collagen alpha- (1497 aa)
initn: 10430 init1: 10430 opt: 10430 Z-score: 3528.9 bits: 665.6 E(85289): 8e-190
Smith-Waterman score: 10430; 99.8% identity (99.9% similar) in 1497 aa overlap (1-1497:1-1497)
10 20 30 40 50 60
pF1KE2 MDVTKKNKRDGTEVTERIVTETVTTRLTSLPPKGGTSNGYAKTASLGGGSRLEKQSLTHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDVTKKNKRDGTEVTERIVTETVTTRLTSLPPKGGTSNGYAKTASLGGGSRLEKQSLTHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SSGYINSTGSTRGHASTSSYRRAHSPASTLPNSPGSTFERKTHVTRHAYEGSSSGNSSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSGYINSTGSTRGHASTSSYRRAHSPASTLPNSPGSTFERKTHVTRHAYEGSSSGNSSPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YPRKEFASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YPRKEFASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 NTLPIPKKGTVETKIVTASSQSVSGTYDAMILDANLPSHVWSSTLPAGSSMGTYHNNMTT
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_000 NTLPIPKKGTVETKIVTASSQSVSGTYDATILDANLPSHVWSSTLPAGSSMGTYHNNMTT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QSSSLLNTNAYSAGSVFGVPNNMASCSPTLHPGLSTSSSVFGMQNNLAPSLTTLSHGTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QSSSLLNTNAYSAGSVFGVPNNMASCSPTLHPGLSTSSSVFGMQNNLAPSLTTLSHGTTT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TSTAYGVKKNMPQSPAAVNTGVSTSAACTTSVQSDDLLHKDCKFLILEKDNTPAKKEMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TSTAYGVKKNMPQSPAAVNTGVSTSAACTTSVQSDDLLHKDCKFLILEKDNTPAKKEMEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LIMTKDSGKVFTASPASIAATSFSEDTLKKEKQAAYNADSGLKAEANGDLKTVSTKGKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LIMTKDSGKVFTASPASIAATSFSEDTLKKEKQAAYNADSGLKAEANGDLKTVSTKGKTT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TADIHSYSSSGGGGSGGGGGVGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLLTWLLLLG
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TADIHSYGSSGGGGSGGGGGVGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLLTWLLLLG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 HSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 PGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPVGPPGPKGDQGEKGPRGL
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_000 PGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 TGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 AGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 ETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 SGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490
pF1KE2 GQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP
1450 1460 1470 1480 1490
>>NP_149162 (OMIM: 108300,120140,132450,150600,151210,15 (1418 aa)
initn: 2077 init1: 715 opt: 1708 Z-score: 597.8 bits: 123.2 E(85289): 1.5e-26
Smith-Waterman score: 1842; 37.6% identity (50.8% similar) in 991 aa overlap (567-1488:189-1064)
540 550 560 570 580 590
pF1KE2 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL
:.:: :. : :::.: ::::::::.::
NP_149 GEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK
160 170 180 190 200 210
600 610 620 630 640
pF1KE2 GHPGPQGPKGQKGSVGDPGMEGPMG---QRGREGPMGPRG------EAGPPGS----GEK
:: : : : :: .: ::..: : . : ::::::: ..:: :. :.
NP_149 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND
220 230 240 250 260 270
650 660 670 680 690 700
pF1KE2 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPV
:. : :: ::: :: : :: : :..: :: : :: : :: ::: : :: : :
NP_149 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS
280 290 300 310 320 330
710 720 730 740 750
pF1KE2 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG-P-----RGEQ
: :: : : :: : : : :.:: : :: .:: :: :: :. : : .:::
NP_149 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ
340 350 360 370 380 390
760 770 780 790 800
pF1KE2 GLTGMPGIRGP---PGPSGDPGK------PGLTGPQGP---QGLPGT---PGRPGIKGEP
: : :: :: :::.:. :: :: .:: :: .: ::. ::. :. :
NP_149 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK
400 410 420 430 440 450
810 820 830 840 850
pF1KE2 GAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNL
::::. .: : :. : : : :: : :: ::: :: ::: : : . . .
NP_149 GAPGE----RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE
460 470 480 490 500 510
860 870 880 890 900
pF1KE2 QGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGP
.: ::::::.: : :.. : :::.: :: :::: :: : ...:: .::
NP_149 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP
520 530 540 550 560 570
910 920 930 940 950 960
pF1KE2 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD
::: :: : .:.:: ::: : :: : :: :.. .. : : :: ::.:..:
NP_149 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF
580 590 600 610 620 630
970 980 990 1000 1010 1020
pF1KE2 PG---VPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY
:: ::: :. : : :. :... .::: :::: :::: . :.. :.
NP_149 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP
640 650 660 670 680 690
1030 1040 1050 1060 1070
pF1KE2 MQSDSIRSYLSGVQGPPG---------PPGPPGPVTTITGETFDYSELASHVVSYLRTSG
..: .: .: :: : :::::. : . . .:.. :
NP_149 -KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA----GANGEKGEVG--------PPG
700 710 720 730 740
1080 1090 1100 1110 1120 1130
pF1KE2 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS
. : . . .: : .. :: : :::::.:. . . . .: ..
NP_149 PAGSAGARGAPGE-------RGETGPP------GPAGFAGPPGADGQPGAKG-EQGEAGQ
750 760 770 780
1140 1150 1160 1170 1180 1190
pF1KE2 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNV
. : . : ::: :: : :: . .. .:. :: :::: : :: : :
NP_149 K--------G-DAGAPGPQGPSGAPGPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRV
790 800 810 820 830
1200 1210 1220 1230 1240 1250
pF1KE2 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS
: . ::::::::: : :: :. : ... :.
NP_149 -------------GPPGSNGNPGPPGPPGPSGKDGPKGARG-------DSGPPGRA----
840 850 860 870
1260 1270 1280 1290 1300
pF1KE2 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV-----RRGSSY
: .. :: :::: .: :::. . : : .. . . .. .::
NP_149 --GEPGLQ----GPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERG
880 890 900 910 920
1310 1320 1330 1340 1350 1360
pF1KE2 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF
.. .: :. :: :: .::::: : .:: : : :.: : : :::
NP_149 FPGLPGPSGEPGKQGAPGA----SGDRGPPGP-VGPPGLTGPAGE----PGREGSPGADG
930 940 950 960 970
1370 1380 1390 1400 1410 1420
pF1KE2 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM
: :. :. . . : . : . ::::.::: :: :
NP_149 PPGRDG---AAGVKGDRGETGAVG--APGAPGPPGSPGPAGPTG----------------
980 990 1000 1010
1430 1440 1450 1460 1470 1480
pF1KE2 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR
:..:: :. :: : :::: : :: :::: ::: :. :.. :.
NP_149 -----------KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH
1020 1030 1040 1050 1060
1490
pF1KE2 RRRRSIAVKP
:
NP_149 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR
1070 1080 1090 1100 1110 1120
>--
initn: 783 init1: 458 opt: 517 Z-score: 197.5 bits: 49.2 E(85289): 0.00029
Smith-Waterman score: 526; 48.2% identity (60.0% similar) in 170 aa overlap (838-1005:31-183)
810 820 830 840 850 860
pF1KE2 IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGP
::: : : :: .. .. :: :::::.::
NP_149 MIRLGAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPG--DIKDIVGPKGPPGPQGP
10 20 30 40 50
870 880 890 900 910 920
pF1KE2 PGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPR
: . :: : :: :: : ::: : : : :: :::::: : ::::
NP_149 AGEQ--GPRGDRGDKGEKGAPGPRGRDGE---------PGTPGNPGPPGPPGPPGPPGLG
60 70 80 90 100
930 940 950 960 970 980
pF1KE2 GHQGEQGLPGFST-SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGS
:. . : ::. .:....:. .::: :: ::.:: : : :: : : :. :.: :
NP_149 GNFAAQMAGGFDEKAGGAQLGV-MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV
110 120 130 140 150 160
990 1000 1010 1020 1030 1040
pF1KE2 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG
:. : :: ::::::: ::
NP_149 SGPM---GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY
170 180 190 200 210 220
>>XP_016874319 (OMIM: 108300,120140,132450,150600,151210 (1465 aa)
initn: 2077 init1: 715 opt: 1708 Z-score: 597.6 bits: 123.2 E(85289): 1.5e-26
Smith-Waterman score: 1842; 37.6% identity (50.8% similar) in 991 aa overlap (567-1488:236-1111)
540 550 560 570 580 590
pF1KE2 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL
:.:: :. : :::.: ::::::::.::
XP_016 GEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK
210 220 230 240 250 260
600 610 620 630 640
pF1KE2 GHPGPQGPKGQKGSVGDPGMEGPMG---QRGREGPMGPRG------EAGPPGS----GEK
:: : : : :: .: ::..: : . : ::::::: ..:: :. :.
XP_016 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND
270 280 290 300 310 320
650 660 670 680 690 700
pF1KE2 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPV
:. : :: ::: :: : :: : :..: :: : :: : :: ::: : :: : :
XP_016 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS
330 340 350 360 370 380
710 720 730 740 750
pF1KE2 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG-P-----RGEQ
: :: : : :: : : : :.:: : :: .:: :: :: :. : : .:::
XP_016 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ
390 400 410 420 430 440
760 770 780 790 800
pF1KE2 GLTGMPGIRGP---PGPSGDPGK------PGLTGPQGP---QGLPGT---PGRPGIKGEP
: : :: :: :::.:. :: :: .:: :: .: ::. ::. :. :
XP_016 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK
450 460 470 480 490 500
810 820 830 840 850
pF1KE2 GAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNL
::::. .: : :. : : : :: : :: ::: :: ::: : : . . .
XP_016 GAPGE----RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE
510 520 530 540 550 560
860 870 880 890 900
pF1KE2 QGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGP
.: ::::::.: : :.. : :::.: :: :::: :: : ...:: .::
XP_016 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP
570 580 590 600 610 620
910 920 930 940 950 960
pF1KE2 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD
::: :: : .:.:: ::: : :: : :: :.. .. : : :: ::.:..:
XP_016 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF
630 640 650 660 670 680
970 980 990 1000 1010 1020
pF1KE2 PG---VPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY
:: ::: :. : : :. :... .::: :::: :::: . :.. :.
XP_016 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP
690 700 710 720 730 740
1030 1040 1050 1060 1070
pF1KE2 MQSDSIRSYLSGVQGPPG---------PPGPPGPVTTITGETFDYSELASHVVSYLRTSG
..: .: .: :: : :::::. : . . .:.. :
XP_016 -KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA----GANGEKGEVG--------PPG
750 760 770 780
1080 1090 1100 1110 1120 1130
pF1KE2 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS
. : . . .: : .. :: : :::::.:. . . . .: ..
XP_016 PAGSAGARGAPGE-------RGETGPP------GPAGFAGPPGADGQPGAKG-EQGEAGQ
790 800 810 820 830
1140 1150 1160 1170 1180 1190
pF1KE2 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNV
. : . : ::: :: : :: . .. .:. :: :::: : :: : :
XP_016 K--------G-DAGAPGPQGPSGAPGPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRV
840 850 860 870 880
1200 1210 1220 1230 1240 1250
pF1KE2 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS
: . ::::::::: : :: :. : ... :.
XP_016 -------------GPPGSNGNPGPPGPPGPSGKDGPKGARG-------DSGPPGRA----
890 900 910
1260 1270 1280 1290 1300
pF1KE2 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV-----RRGSSY
: .. :: :::: .: :::. . : : .. . . .. .::
XP_016 --GEPGLQ----GPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERG
920 930 940 950 960 970
1310 1320 1330 1340 1350 1360
pF1KE2 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF
.. .: :. :: :: .::::: : .:: : : :.: : : :::
XP_016 FPGLPGPSGEPGKQGAPGA----SGDRGPPGP-VGPPGLTGPAGE----PGREGSPGADG
980 990 1000 1010 1020
1370 1380 1390 1400 1410 1420
pF1KE2 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM
: :. :. . . : . : . ::::.::: :: :
XP_016 PPGRDG---AAGVKGDRGETGAVG--APGAPGPPGSPGPAGPTG----------------
1030 1040 1050 1060
1430 1440 1450 1460 1470 1480
pF1KE2 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR
:..:: :. :: : :::: : :: :::: ::: :. :.. :.
XP_016 -----------KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH
1070 1080 1090 1100 1110
1490
pF1KE2 RRRRSIAVKP
:
XP_016 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR
1120 1130 1140 1150 1160 1170
>--
initn: 783 init1: 458 opt: 517 Z-score: 197.4 bits: 49.2 E(85289): 0.0003
Smith-Waterman score: 528; 40.4% identity (53.5% similar) in 230 aa overlap (778-1005:31-230)
750 760 770 780 790 800
pF1KE2 DGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGK
::. : : : :..: .: .
XP_016 MGAWRLRQGPWKFFGGPYRSKGRSVWGRFLPGMKGGTGDQ--EKRPAKPWEEGSLAKTLV
10 20 30 40 50
810 820 830 840 850 860
pF1KE2 IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGP
..: ...: : ::: : : :: .. .. :: :::::.::
XP_016 LLTLLVAAVLRCQGQD-----------VRQPGPKGQKGEPG--DIKDIVGPKGPPGPQGP
60 70 80 90 100
870 880 890 900 910 920
pF1KE2 PGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPR
: . :: : :: :: : ::: : : : :: :::::: : ::::
XP_016 AGEQ--GPRGDRGDKGEKGAPGPRGRDGE---------PGTPGNPGPPGPPGPPGPPGLG
110 120 130 140 150
930 940 950 960 970 980
pF1KE2 GHQGEQGLPGFST-SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGS
:. . : ::. .:....:. .::: :: ::.:: : : :: : : :. :.: :
XP_016 GNFAAQMAGGFDEKAGGAQLGV-MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV
160 170 180 190 200 210
990 1000 1010 1020 1030 1040
pF1KE2 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG
:. : :: ::::::: ::
XP_016 SGPM---GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY
220 230 240 250 260 270
>>NP_001835 (OMIM: 108300,120140,132450,150600,151210,15 (1487 aa)
initn: 2077 init1: 715 opt: 1708 Z-score: 597.6 bits: 123.2 E(85289): 1.5e-26
Smith-Waterman score: 1842; 37.6% identity (50.8% similar) in 991 aa overlap (567-1488:258-1133)
540 550 560 570 580 590
pF1KE2 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL
:.:: :. : :::.: ::::::::.::
NP_001 GEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK
230 240 250 260 270 280
600 610 620 630 640
pF1KE2 GHPGPQGPKGQKGSVGDPGMEGPMG---QRGREGPMGPRG------EAGPPGS----GEK
:: : : : :: .: ::..: : . : ::::::: ..:: :. :.
NP_001 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND
290 300 310 320 330 340
650 660 670 680 690 700
pF1KE2 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPV
:. : :: ::: :: : :: : :..: :: : :: : :: ::: : :: : :
NP_001 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS
350 360 370 380 390 400
710 720 730 740 750
pF1KE2 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG-P-----RGEQ
: :: : : :: : : : :.:: : :: .:: :: :: :. : : .:::
NP_001 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ
410 420 430 440 450 460
760 770 780 790 800
pF1KE2 GLTGMPGIRGP---PGPSGDPGK------PGLTGPQGP---QGLPGT---PGRPGIKGEP
: : :: :: :::.:. :: :: .:: :: .: ::. ::. :. :
NP_001 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK
470 480 490 500 510 520
810 820 830 840 850
pF1KE2 GAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNL
::::. .: : :. : : : :: : :: ::: :: ::: : : . . .
NP_001 GAPGE----RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE
530 540 550 560 570 580
860 870 880 890 900
pF1KE2 QGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGP
.: ::::::.: : :.. : :::.: :: :::: :: : ...:: .::
NP_001 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP
590 600 610 620 630 640
910 920 930 940 950 960
pF1KE2 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD
::: :: : .:.:: ::: : :: : :: :.. .. : : :: ::.:..:
NP_001 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF
650 660 670 680 690 700
970 980 990 1000 1010 1020
pF1KE2 PG---VPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY
:: ::: :. : : :. :... .::: :::: :::: . :.. :.
NP_001 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP
710 720 730 740 750 760
1030 1040 1050 1060 1070
pF1KE2 MQSDSIRSYLSGVQGPPG---------PPGPPGPVTTITGETFDYSELASHVVSYLRTSG
..: .: .: :: : :::::. : . . .:.. :
NP_001 -KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA----GANGEKGEVG--------PPG
770 780 790 800 810
1080 1090 1100 1110 1120 1130
pF1KE2 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS
. : . . .: : .. :: : :::::.:. . . . .: ..
NP_001 PAGSAGARGAPGE-------RGETGPP------GPAGFAGPPGADGQPGAKG-EQGEAGQ
820 830 840 850
1140 1150 1160 1170 1180 1190
pF1KE2 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNV
. : . : ::: :: : :: . .. .:. :: :::: : :: : :
NP_001 K--------G-DAGAPGPQGPSGAPGPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRV
860 870 880 890 900
1200 1210 1220 1230 1240 1250
pF1KE2 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS
: . ::::::::: : :: :. : ... :.
NP_001 -------------GPPGSNGNPGPPGPPGPSGKDGPKGARG-------DSGPPGRA----
910 920 930 940
1260 1270 1280 1290 1300
pF1KE2 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV-----RRGSSY
: .. :: :::: .: :::. . : : .. . . .. .::
NP_001 --GEPGLQ----GPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERG
950 960 970 980 990
1310 1320 1330 1340 1350 1360
pF1KE2 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF
.. .: :. :: :: .::::: : .:: : : :.: : : :::
NP_001 FPGLPGPSGEPGKQGAPGA----SGDRGPPGP-VGPPGLTGPAGE----PGREGSPGADG
1000 1010 1020 1030 1040
1370 1380 1390 1400 1410 1420
pF1KE2 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM
: :. :. . . : . : . ::::.::: :: :
NP_001 PPGRDG---AAGVKGDRGETGAVG--APGAPGPPGSPGPAGPTG----------------
1050 1060 1070 1080
1430 1440 1450 1460 1470 1480
pF1KE2 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR
:..:: :. :: : :::: : :: :::: ::: :. :.. :.
NP_001 -----------KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH
1090 1100 1110 1120 1130
1490
pF1KE2 RRRRSIAVKP
:
NP_001 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR
1140 1150 1160 1170 1180 1190
>--
initn: 783 init1: 458 opt: 537 Z-score: 204.0 bits: 50.4 E(85289): 0.00013
Smith-Waterman score: 537; 45.8% identity (56.2% similar) in 192 aa overlap (822-1005:78-252)
800 810 820 830 840
pF1KE2 TPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPP------GAPGPAGPAG
: : : : : : ::: : :
NP_001 KPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKG
50 60 70 80 90 100
850 860 870 880 890 900
pF1KE2 LPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFL
:: .. .. :: :::::.:: : . :: : :: :: : ::: : :
NP_001 EPG--DIKDIVGPKGPPGPQGPAGEQ--GPRGDRGDKGEKGAPGPRGRDGE---------
110 120 130 140 150
910 920 930 940 950 960
pF1KE2 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFST-SGSSSFGLNLQGPPGPPGPQGPKG
: :: :::::: : :::: :. . : ::. .:....:. .::: :: ::.:: :
NP_001 PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV-MQGPMGPMGPRGPPG
160 170 180 190 200 210
970 980 990 1000 1010 1020
pF1KE2 DKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQ
: :: : : :. :.: : :. : :: ::::::: ::
NP_001 PAGAPGPQGFQGNPGEPGEPGVSGPM---GPRGPPGPPGKPGDDGEAGKPGKAGERGPPG
220 230 240 250 260 270
1030 1040 1050 1060 1070 1080
pF1KE2 SDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSIS
NP_001 PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG
280 290 300 310 320 330
>>XP_016874318 (OMIM: 108300,120140,132450,150600,151210 (1534 aa)
initn: 2077 init1: 715 opt: 1708 Z-score: 597.4 bits: 123.2 E(85289): 1.6e-26
Smith-Waterman score: 1842; 37.6% identity (50.8% similar) in 991 aa overlap (567-1488:305-1180)
540 550 560 570 580 590
pF1KE2 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL
:.:: :. : :::.: ::::::::.::
XP_016 GEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK
280 290 300 310 320 330
600 610 620 630 640
pF1KE2 GHPGPQGPKGQKGSVGDPGMEGPMG---QRGREGPMGPRG------EAGPPGS----GEK
:: : : : :: .: ::..: : . : ::::::: ..:: :. :.
XP_016 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND
340 350 360 370 380 390
650 660 670 680 690 700
pF1KE2 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPV
:. : :: ::: :: : :: : :..: :: : :: : :: ::: : :: : :
XP_016 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS
400 410 420 430 440 450
710 720 730 740 750
pF1KE2 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG-P-----RGEQ
: :: : : :: : : : :.:: : :: .:: :: :: :. : : .:::
XP_016 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ
460 470 480 490 500 510
760 770 780 790 800
pF1KE2 GLTGMPGIRGP---PGPSGDPGK------PGLTGPQGP---QGLPGT---PGRPGIKGEP
: : :: :: :::.:. :: :: .:: :: .: ::. ::. :. :
XP_016 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK
520 530 540 550 560 570
810 820 830 840 850
pF1KE2 GAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNL
::::. .: : :. : : : :: : :: ::: :: ::: : : . . .
XP_016 GAPGE----RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE
580 590 600 610 620 630
860 870 880 890 900
pF1KE2 QGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGP
.: ::::::.: : :.. : :::.: :: :::: :: : ...:: .::
XP_016 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP
640 650 660 670 680 690
910 920 930 940 950 960
pF1KE2 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD
::: :: : .:.:: ::: : :: : :: :.. .. : : :: ::.:..:
XP_016 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF
700 710 720 730 740 750
970 980 990 1000 1010 1020
pF1KE2 PG---VPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY
:: ::: :. : : :. :... .::: :::: :::: . :.. :.
XP_016 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP
760 770 780 790 800 810
1030 1040 1050 1060 1070
pF1KE2 MQSDSIRSYLSGVQGPPG---------PPGPPGPVTTITGETFDYSELASHVVSYLRTSG
..: .: .: :: : :::::. : . . .:.. :
XP_016 -KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA----GANGEKGEVG--------PPG
820 830 840 850
1080 1090 1100 1110 1120 1130
pF1KE2 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS
. : . . .: : .. :: : :::::.:. . . . .: ..
XP_016 PAGSAGARGAPGE-------RGETGPP------GPAGFAGPPGADGQPGAKG-EQGEAGQ
860 870 880 890 900
1140 1150 1160 1170 1180 1190
pF1KE2 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNV
. : . : ::: :: : :: . .. .:. :: :::: : :: : :
XP_016 K--------G-DAGAPGPQGPSGAPGPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRV
910 920 930 940 950
1200 1210 1220 1230 1240 1250
pF1KE2 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS
: . ::::::::: : :: :. : ... :.
XP_016 -------------GPPGSNGNPGPPGPPGPSGKDGPKGARG-------DSGPPGRA----
960 970 980
1260 1270 1280 1290 1300
pF1KE2 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV-----RRGSSY
: .. :: :::: .: :::. . : : .. . . .. .::
XP_016 --GEPGLQ----GPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERG
990 1000 1010 1020 1030 1040
1310 1320 1330 1340 1350 1360
pF1KE2 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF
.. .: :. :: :: .::::: : .:: : : :.: : : :::
XP_016 FPGLPGPSGEPGKQGAPGA----SGDRGPPGP-VGPPGLTGPAGE----PGREGSPGADG
1050 1060 1070 1080 1090
1370 1380 1390 1400 1410 1420
pF1KE2 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM
: :. :. . . : . : . ::::.::: :: :
XP_016 PPGRDG---AAGVKGDRGETGAVG--APGAPGPPGSPGPAGPTG----------------
1100 1110 1120 1130
1430 1440 1450 1460 1470 1480
pF1KE2 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR
:..:: :. :: : :::: : :: :::: ::: :. :.. :.
XP_016 -----------KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH
1140 1150 1160 1170
1490
pF1KE2 RRRRSIAVKP
:
XP_016 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR
1180 1190 1200 1210 1220 1230
>--
initn: 783 init1: 458 opt: 537 Z-score: 203.8 bits: 50.4 E(85289): 0.00013
Smith-Waterman score: 537; 45.8% identity (56.2% similar) in 192 aa overlap (822-1005:125-299)
800 810 820 830 840
pF1KE2 TPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPP------GAPGPAGPAG
: : : : : : ::: : :
XP_016 KPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKG
100 110 120 130 140 150
850 860 870 880 890 900
pF1KE2 LPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFL
:: .. .. :: :::::.:: : . :: : :: :: : ::: : :
XP_016 EPG--DIKDIVGPKGPPGPQGPAGEQ--GPRGDRGDKGEKGAPGPRGRDGE---------
160 170 180 190 200
910 920 930 940 950 960
pF1KE2 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFST-SGSSSFGLNLQGPPGPPGPQGPKG
: :: :::::: : :::: :. . : ::. .:....:. .::: :: ::.:: :
XP_016 PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV-MQGPMGPMGPRGPPG
210 220 230 240 250 260
970 980 990 1000 1010 1020
pF1KE2 DKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQ
: :: : : :. :.: : :. : :: ::::::: ::
XP_016 PAGAPGPQGFQGNPGEPGEPGVSGPM---GPRGPPGPPGKPGDDGEAGKPGKAGERGPPG
270 280 290 300 310
1030 1040 1050 1060 1070 1080
pF1KE2 SDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSIS
XP_016 PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG
320 330 340 350 360 370
>>XP_016874317 (OMIM: 108300,120140,132450,150600,151210 (1535 aa)
initn: 2077 init1: 715 opt: 1708 Z-score: 597.4 bits: 123.2 E(85289): 1.6e-26
Smith-Waterman score: 1842; 37.6% identity (50.8% similar) in 991 aa overlap (567-1488:306-1181)
540 550 560 570 580 590
pF1KE2 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL
:.:: :. : :::.: ::::::::.::
XP_016 GEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK
280 290 300 310 320 330
600 610 620 630 640
pF1KE2 GHPGPQGPKGQKGSVGDPGMEGPMG---QRGREGPMGPRG------EAGPPGS----GEK
:: : : : :: .: ::..: : . : ::::::: ..:: :. :.
XP_016 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND
340 350 360 370 380 390
650 660 670 680 690 700
pF1KE2 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPV
:. : :: ::: :: : :: : :..: :: : :: : :: ::: : :: : :
XP_016 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS
400 410 420 430 440 450
710 720 730 740 750
pF1KE2 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG-P-----RGEQ
: :: : : :: : : : :.:: : :: .:: :: :: :. : : .:::
XP_016 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ
460 470 480 490 500 510
760 770 780 790 800
pF1KE2 GLTGMPGIRGP---PGPSGDPGK------PGLTGPQGP---QGLPGT---PGRPGIKGEP
: : :: :: :::.:. :: :: .:: :: .: ::. ::. :. :
XP_016 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK
520 530 540 550 560 570
810 820 830 840 850
pF1KE2 GAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNL
::::. .: : :. : : : :: : :: ::: :: ::: : : . . .
XP_016 GAPGE----RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE
580 590 600 610 620 630
860 870 880 890 900
pF1KE2 QGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGP
.: ::::::.: : :.. : :::.: :: :::: :: : ...:: .::
XP_016 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP
640 650 660 670 680 690
910 920 930 940 950 960
pF1KE2 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD
::: :: : .:.:: ::: : :: : :: :.. .. : : :: ::.:..:
XP_016 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF
700 710 720 730 740 750
970 980 990 1000 1010 1020
pF1KE2 PG---VPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY
:: ::: :. : : :. :... .::: :::: :::: . :.. :.
XP_016 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP
760 770 780 790 800 810
1030 1040 1050 1060 1070
pF1KE2 MQSDSIRSYLSGVQGPPG---------PPGPPGPVTTITGETFDYSELASHVVSYLRTSG
..: .: .: :: : :::::. : . . .:.. :
XP_016 -KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA----GANGEKGEVG--------PPG
820 830 840 850
1080 1090 1100 1110 1120 1130
pF1KE2 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS
. : . . .: : .. :: : :::::.:. . . . .: ..
XP_016 PAGSAGARGAPGE-------RGETGPP------GPAGFAGPPGADGQPGAKG-EQGEAGQ
860 870 880 890 900
1140 1150 1160 1170 1180 1190
pF1KE2 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNV
. : . : ::: :: : :: . .. .:. :: :::: : :: : :
XP_016 K--------G-DAGAPGPQGPSGAPGPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRV
910 920 930 940 950
1200 1210 1220 1230 1240 1250
pF1KE2 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS
: . ::::::::: : :: :. : ... :.
XP_016 -------------GPPGSNGNPGPPGPPGPSGKDGPKGARG-------DSGPPGRA----
960 970 980
1260 1270 1280 1290 1300
pF1KE2 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV-----RRGSSY
: .. :: :::: .: :::. . : : .. . . .. .::
XP_016 --GEPGLQ----GPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERG
990 1000 1010 1020 1030 1040
1310 1320 1330 1340 1350 1360
pF1KE2 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF
.. .: :. :: :: .::::: : .:: : : :.: : : :::
XP_016 FPGLPGPSGEPGKQGAPGA----SGDRGPPGP-VGPPGLTGPAGE----PGREGSPGADG
1050 1060 1070 1080 1090
1370 1380 1390 1400 1410 1420
pF1KE2 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM
: :. :. . . : . : . ::::.::: :: :
XP_016 PPGRDG---AAGVKGDRGETGAVG--APGAPGPPGSPGPAGPTG----------------
1100 1110 1120 1130
1430 1440 1450 1460 1470 1480
pF1KE2 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR
:..:: :. :: : :::: : :: :::: ::: :. :.. :.
XP_016 -----------KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH
1140 1150 1160 1170 1180
1490
pF1KE2 RRRRSIAVKP
:
XP_016 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR
1190 1200 1210 1220 1230 1240
>--
initn: 783 init1: 458 opt: 525 Z-score: 199.8 bits: 49.7 E(85289): 0.00022
Smith-Waterman score: 526; 48.2% identity (60.0% similar) in 170 aa overlap (838-1005:148-300)
810 820 830 840 850 860
pF1KE2 IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGP
::: : : :: .. .. :: :::::.::
XP_016 DVKDCLSPEIPFGECCPICPTDLATASGWQPGPKGQKGEPG--DIKDIVGPKGPPGPQGP
120 130 140 150 160 170
870 880 890 900 910 920
pF1KE2 PGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPR
: . :: : :: :: : ::: : : : :: :::::: : ::::
XP_016 AGEQ--GPRGDRGDKGEKGAPGPRGRDGE---------PGTPGNPGPPGPPGPPGPPGLG
180 190 200 210 220
930 940 950 960 970 980
pF1KE2 GHQGEQGLPGFST-SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGS
:. . : ::. .:....:. .::: :: ::.:: : : :: : : :. :.: :
XP_016 GNFAAQMAGGFDEKAGGAQLGV-MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGV
230 240 250 260 270 280
990 1000 1010 1020 1030 1040
pF1KE2 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG
:. : :: ::::::: ::
XP_016 SGPM---GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY
290 300 310 320 330 340
>>XP_016874320 (OMIM: 108300,120140,132450,150600,151210 (1305 aa)
initn: 2077 init1: 715 opt: 1681 Z-score: 589.2 bits: 121.5 E(85289): 4.4e-26
Smith-Waterman score: 1842; 37.6% identity (50.8% similar) in 991 aa overlap (567-1488:76-951)
540 550 560 570 580 590
pF1KE2 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL
:.:: :. : :::.: ::::::::.::
XP_016 GEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK
50 60 70 80 90 100
600 610 620 630 640
pF1KE2 GHPGPQGPKGQKGSVGDPGMEGPMG---QRGREGPMGPRG------EAGPPGS----GEK
:: : : : :: .: ::..: : . : ::::::: ..:: :. :.
XP_016 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND
110 120 130 140 150 160
650 660 670 680 690 700
pF1KE2 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPV
:. : :: ::: :: : :: : :..: :: : :: : :: ::: : :: : :
XP_016 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS
170 180 190 200 210 220
710 720 730 740 750
pF1KE2 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG-P-----RGEQ
: :: : : :: : : : :.:: : :: .:: :: :: :. : : .:::
XP_016 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ
230 240 250 260 270 280
760 770 780 790 800
pF1KE2 GLTGMPGIRGP---PGPSGDPGK------PGLTGPQGP---QGLPGT---PGRPGIKGEP
: : :: :: :::.:. :: :: .:: :: .: ::. ::. :. :
XP_016 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK
290 300 310 320 330 340
810 820 830 840 850
pF1KE2 GAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNL
::::. .: : :. : : : :: : :: ::: :: ::: : : . . .
XP_016 GAPGE----RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE
350 360 370 380 390 400
860 870 880 890 900
pF1KE2 QGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGP
.: ::::::.: : :.. : :::.: :: :::: :: : ...:: .::
XP_016 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP
410 420 430 440 450 460
910 920 930 940 950 960
pF1KE2 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD
::: :: : .:.:: ::: : :: : :: :.. .. : : :: ::.:..:
XP_016 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF
470 480 490 500 510 520
970 980 990 1000 1010 1020
pF1KE2 PG---VPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY
:: ::: :. : : :. :... .::: :::: :::: . :.. :.
XP_016 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP
530 540 550 560 570 580
1030 1040 1050 1060 1070
pF1KE2 MQSDSIRSYLSGVQGPPG---------PPGPPGPVTTITGETFDYSELASHVVSYLRTSG
..: .: .: :: : :::::. : . . .:.. :
XP_016 -KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA----GANGEKGEVG--------PPG
590 600 610 620
1080 1090 1100 1110 1120 1130
pF1KE2 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS
. : . . .: : .. :: : :::::.:. . . . .: ..
XP_016 PAGSAGARGAPGE-------RGETGPP------GPAGFAGPPGADGQPGAKG-EQGEAGQ
630 640 650 660 670
1140 1150 1160 1170 1180 1190
pF1KE2 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNV
. : . : ::: :: : :: . .. .:. :: :::: : :: : :
XP_016 K--------G-DAGAPGPQGPSGAPGPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRV
680 690 700 710 720
1200 1210 1220 1230 1240 1250
pF1KE2 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS
: . ::::::::: : :: :. : ... :.
XP_016 -------------GPPGSNGNPGPPGPPGPSGKDGPKGARG-------DSGPPGRA----
730 740 750
1260 1270 1280 1290 1300
pF1KE2 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV-----RRGSSY
: .. :: :::: .: :::. . : : .. . . .. .::
XP_016 --GEPGLQ----GPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERG
760 770 780 790 800 810
1310 1320 1330 1340 1350 1360
pF1KE2 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF
.. .: :. :: :: .::::: : .:: : : :.: : : :::
XP_016 FPGLPGPSGEPGKQGAPGA----SGDRGPPGP-VGPPGLTGPAGE----PGREGSPGADG
820 830 840 850 860
1370 1380 1390 1400 1410 1420
pF1KE2 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM
: :. :. . . : . : . ::::.::: :: :
XP_016 PPGRDG---AAGVKGDRGETGAVG--APGAPGPPGSPGPAGPTG----------------
870 880 890 900
1430 1440 1450 1460 1470 1480
pF1KE2 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR
:..:: :. :: : :::: : :: :::: ::: :. :.. :.
XP_016 -----------KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH
910 920 930 940 950
1490
pF1KE2 RRRRSIAVKP
:
XP_016 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR
960 970 980 990 1000 1010
>>NP_690848 (OMIM: 610026) collagen alpha-1(XXII) chain (1626 aa)
initn: 824 init1: 824 opt: 1603 Z-score: 561.8 bits: 116.7 E(85289): 1.5e-24
Smith-Waterman score: 1742; 36.8% identity (50.6% similar) in 995 aa overlap (561-1486:531-1435)
540 550 560 570 580 590
pF1KE2 AGADLDKIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTP
:.:.: : ::: : :: : .:. : : :
NP_690 IGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSL-GLPGPPGRDGSKGMRGEPGELGEP
510 520 530 540 550
600 610 620 630
pF1KE2 GIPGPLGHPGPQGPKG---QKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPG--------
:.:: .: ::::: : : :: ::..: :..: .: : :: : ::
NP_690 GLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQ
560 570 580 590 600 610
640 650 660 670 680
pF1KE2 -----SGEKGERGAAGEPGPHGPPGVPGSV-------------GPKGSSGSPGPQGPPGP
:: : .: :. :: ::::::::: ::.: .:.::: : ::
NP_690 GRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGP
620 630 640 650 660 670
690 700 710 720 730
pF1KE2 VGLQGLRGEVGLPGVKGDKGPVGPPG-PK--GDQGEKGPRGLTGEPG---MRGLPGAVGE
.: .: : :: :..: :: .:::: : : :: :: :. : :: :::: .:
NP_690 IGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGF
680 690 700 710 720 730
740 750 760 770 780 790
pF1KE2 PGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGD---PGKPGLTGPQGPQGLPGT
:: : ::.:: :..:: : : :: .: :: :. :::::: : : ::: :
NP_690 PGKPGPPGPTGPPGKDGPNGPPG---PPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGR
740 750 760 770 780 790
800 810 820 830 840 850
pF1KE2 PGRPGIKGEPGAPG-KIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQE
::. : : ::::: : .: ... : : :: : : : ::::: ::::
NP_690 PGEKGEAGLPGAPGFPGVRGEKGDQGE-KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTS
800 810 820 830 840 850
860 870 880 890 900
pF1KE2 VLNLQGP--PGPPGPRGPPG-PSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGP
... . : :: ::.: : :..:: :: .: ::: : :: ::::. ... :
NP_690 LFTPH-PRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA---KGQEGAHGA
860 870 880 890 900 910
910 920 930 940 950 960
pF1KE2 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGF-STSGSSSF-GLN-LQGPPGPPGPQGPKGD
:: : :: : : ::: : : : ::. .: :... : . : : ::: ::.::
NP_690 PGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGD
920 930 940 950 960 970
970 980 990 1000 1010 1020
pF1KE2 KGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISS-SGQEIQQYISEYMQ
: ::.:: : : .. : . . : :: ::: : .. .. :.: .. ..
NP_690 PGAPGLPG----PPGKGKDGEPG---LRGSPGLPGPLGTKAACGKVRGSENCALGGQCVK
980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KE2 SDSIRSYLSGVQGPPGPPG-----PPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLF
.: . : : : :: :::: .: : . .:. :. :
NP_690 GDRGAPGIPGSPGSRGDPGIGVAGPPGP----SGPPGDKGSPGSR----------GLPGF
1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KE2 SSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSL-DYAELSSRILSY
. . :: . : ::::: :: : :::: : :.. . .
NP_690 PGPQGPAG------RDGAPGN-----PGERGPPGKPGLS---SLLSPGDINLLAKDVCND
1080 1090 1100 1110
1140 1150 1160 1170 1180 1190
pF1KE2 MSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF----RGIVGPPGPPGPPGIPGNVW
::::: ::::: . .. . : : .: .:::: :::::: :
NP_690 CP--------PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG
1120 1130 1140 1150 1160
1200 1210 1220 1230 1240 1250
pF1KE2 SSI--SVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELI
:. ... . : .:: :::: ::: : :..:: . . ..: . ..
NP_690 SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG
1170 1180 1190 1200 1210 1220
1260 1270 1280 1290 1300
pF1KE2 SYLTS--PDV-----RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRG
: : . . : ::::: : :. : . ... :: . .:
NP_690 PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA--RGPPGF-------KG
1230 1240 1250 1260 1270
1310 1320 1330 1340 1350 1360
pF1KE2 SSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGL
. .:. : .:..: : : . :: :: : . :: : : ...: :. :
NP_690 HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQ-GPQGPRGPPGKNGS-PGSPGE
1280 1290 1300 1310 1320 1330
1370 1380 1390 1400 1410 1420
pF1KE2 LG-ADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSN
: . :. . :.. . . : :. .::::.:: .: :: : .
NP_690 PGPSGTPGQ--------KGSKGENGSPGLPGF-LGPRGPPGEPGEKGVPGKEGVPGK---
1340 1350 1360 1370 1380
1430 1440 1450 1460 1470 1480
pF1KE2 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD
: :: ::: : :: :::.:: : :.:: :: ::::. : :
NP_690 ---------------PGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGP
1390 1400 1410 1420 1430
1490
pF1KE2 QVYAGRRRRRSIAVKP
: :
NP_690 QGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPA
1440 1450 1460 1470 1480 1490
>>XP_011515189 (OMIM: 610026) PREDICTED: collagen alpha- (1264 aa)
initn: 824 init1: 824 opt: 1543 Z-score: 543.0 bits: 112.9 E(85289): 1.7e-23
Smith-Waterman score: 1808; 35.3% identity (51.7% similar) in 1042 aa overlap (509-1475:179-1163)
480 490 500 510 520 530
pF1KE2 LGLLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKI
: :.:.. .. :: : :. : : .:
XP_011 PMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQG-EKGEKGSL-GLPGPPGRDGSK-
150 160 170 180 190 200
540 550 560 570 580
pF1KE2 GLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRG-------------
:.... : . .. :. .: : ::: : .:.:: .:.::
XP_011 GMRGEPGELGEPGLPGEVGMRGPQGP-PGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL
210 220 230 240 250 260
590 600 610 620 630
pF1KE2 --FPGTPGIPGPLGHPGPQG---PKGQKGSVGD---PGM-------EGPMGQRGREGPMG
::: :: : :.:::.: :.:.::.:: ::. :: :..: :: :
XP_011 DGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRG
270 280 290 300 310 320
640 650 660 670 680
pF1KE2 PRGEAGPPGS----------GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPG
.: ::::. : : .: :. : ::::.:: .: .: : :: ::::
XP_011 HQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG
330 340 350 360 370 380
690 700 710 720 730 740
pF1KE2 PVGLQGLRGEVGLPGVKGDKGPVGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKG
: : :: ::.:.:: : ::.:::: : .: :: : :::: :: : :.:: .:
XP_011 PGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG
390 400 410 420 430 440
750 760 770 780 790 800
pF1KE2 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG
.: : :. : .:: :: : ::. : : .:: :. : : : .: : :. : :
XP_011 EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG
450 460 470 480 490 500
810 820 830 840 850 860
pF1KE2 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG
:: :: .:: . .:: :: : : :: :: :: : ::. :. ::: :
XP_011 PPGLPG--TTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR---PGE---LGPQGPTG
510 520 530 540 550
870 880 890 900 910
pF1KE2 PPGPRGPPGP-SIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKG
::: .: : . :: : : ::. : ::: ::::: . . : : :: : : ::
XP_011 PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG---LRGTPGKDGERGEKG
560 570 580 590 600 610
920 930 940 950 960 970
pF1KE2 ------DQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG
. :: :::: : :::: .:... .:.: :: ::: : :::.: ::.::
XP_011 AAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP-GLRGSPGLPGPLGTKGDRGAPGIPG
620 630 640 650 660 670
980 990 1000 1010 1020 1030
pF1KE2 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS
. : . :. : :.::::: :::: :: .: : . . . :. . :.
XP_011 SPGSRGDPGIG-------VAGPPGPSGPPGDKGSPGSRG--LPGFPGP--QGPAGRDGAP
680 690 700 710 720
1040 1050 1060 1070 1080 1090
pF1KE2 GVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQ
: : :::: :: . .. : . ::. : . . :. . . ... . .
XP_011 GNPGERGPPGKPGLSSLLS--PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG
730 740 750 760 770
1100 1110 1120 1130 1140 1150
pF1KE2 RDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS--IGLPGP
:. .. .. :: : ::::: .: . . :. . .. :. .: ::
XP_011 REGTEG--KKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN
780 790 800 810 820 830
1160 1170 1180 1190 1200 1210
pF1KE2 PGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGL
::::: : . ..:: : ::::: :: :.:: . . . : .. :
XP_011 PGPPGADGIAGAAGPPGIQGSP--GKEGPPGPQGPSGLPG-IPGEEGKEGRDGKPGPPGE
840 850 860 870 880 890
1220 1230 1240 1250 1260
pF1KE2 SFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSEL----ISYLTSPDVRSFIVGP
: :: ::: : ::::: .: . .: . . . . : . : . .::
XP_011 PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP
900 910 920 930 940 950
1270 1280 1290 1300 1310
pF1KE2 PGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGS----SYSSSMSTGG-----GG
:: ::.:::: . .. . . ... ....:. . :: .. . . : :
XP_011 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV
960 970 980 990 1000 1010
1320 1330 1340 1350 1360 1370
pF1KE2 AGSLGAGGAFGEAA--GDRGPYGT--DIGPGGGYGAAAEGGM--YAGNGGLLGADFAGDL
:. :. : :: . :.:: : : :: :: : .. :. . :. ::.:
XP_011 PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGP------
1020 1030 1040 1050 1060
1380 1390 1400 1410 1420
pF1KE2 DYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGIS----KVFSAYSNVTADLM
::: : : :::: :: : ::. .. . . .:
XP_011 ---------------QGL-PGENGPV-GPPGPPGQPGFPGLRGESPSMETLRRLIQEELG
1070 1080 1090 1100 1110
1430 1440 1450 1460 1470 1480
pF1KE2 DFFQT---YGAIQGPPG-QKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQV
..: : : ::. .:. .: ::: : : : ::. :: : :. :.
XP_011 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG
1120 1130 1140 1150 1160 1170
1490
pF1KE2 YAGRRRRRSIAVKP
XP_011 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHP
1180 1190 1200 1210 1220 1230
>>XP_016868641 (OMIM: 610026) PREDICTED: collagen alpha- (1264 aa)
initn: 824 init1: 824 opt: 1543 Z-score: 543.0 bits: 112.9 E(85289): 1.7e-23
Smith-Waterman score: 1808; 35.3% identity (51.7% similar) in 1042 aa overlap (509-1475:179-1163)
480 490 500 510 520 530
pF1KE2 LGLLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKI
: :.:.. .. :: : :. : : .:
XP_016 PMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQG-EKGEKGSL-GLPGPPGRDGSK-
150 160 170 180 190 200
540 550 560 570 580
pF1KE2 GLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRG-------------
:.... : . .. :. .: : ::: : .:.:: .:.::
XP_016 GMRGEPGELGEPGLPGEVGMRGPQGP-PGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL
210 220 230 240 250 260
590 600 610 620 630
pF1KE2 --FPGTPGIPGPLGHPGPQG---PKGQKGSVGD---PGM-------EGPMGQRGREGPMG
::: :: : :.:::.: :.:.::.:: ::. :: :..: :: :
XP_016 DGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRG
270 280 290 300 310 320
640 650 660 670 680
pF1KE2 PRGEAGPPGS----------GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPG
.: ::::. : : .: :. : ::::.:: .: .: : :: ::::
XP_016 HQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG
330 340 350 360 370 380
690 700 710 720 730 740
pF1KE2 PVGLQGLRGEVGLPGVKGDKGPVGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKG
: : :: ::.:.:: : ::.:::: : .: :: : :::: :: : :.:: .:
XP_016 PGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG
390 400 410 420 430 440
750 760 770 780 790 800
pF1KE2 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG
.: : :. : .:: :: : ::. : : .:: :. : : : .: : :. : :
XP_016 EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG
450 460 470 480 490 500
810 820 830 840 850 860
pF1KE2 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG
:: :: .:: . .:: :: : : :: :: :: : ::. :. ::: :
XP_016 PPGLPG--TTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR---PGE---LGPQGPTG
510 520 530 540 550
870 880 890 900 910
pF1KE2 PPGPRGPPGP-SIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKG
::: .: : . :: : : ::. : ::: ::::: . . : : :: : : ::
XP_016 PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG---LRGTPGKDGERGEKG
560 570 580 590 600 610
920 930 940 950 960 970
pF1KE2 ------DQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG
. :: :::: : :::: .:... .:.: :: ::: : :::.: ::.::
XP_016 AAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP-GLRGSPGLPGPLGTKGDRGAPGIPG
620 630 640 650 660 670
980 990 1000 1010 1020 1030
pF1KE2 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS
. : . :. : :.::::: :::: :: .: : . . . :. . :.
XP_016 SPGSRGDPGIG-------VAGPPGPSGPPGDKGSPGSRG--LPGFPGP--QGPAGRDGAP
680 690 700 710 720
1040 1050 1060 1070 1080 1090
pF1KE2 GVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQ
: : :::: :: . .. : . ::. : . . :. . . ... . .
XP_016 GNPGERGPPGKPGLSSLLS--PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG
730 740 750 760 770
1100 1110 1120 1130 1140 1150
pF1KE2 RDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS--IGLPGP
:. .. .. :: : ::::: .: . . :. . .. :. .: ::
XP_016 REGTEG--KKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN
780 790 800 810 820 830
1160 1170 1180 1190 1200 1210
pF1KE2 PGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGL
::::: : . ..:: : ::::: :: :.:: . . . : .. :
XP_016 PGPPGADGIAGAAGPPGIQGSP--GKEGPPGPQGPSGLPG-IPGEEGKEGRDGKPGPPGE
840 850 860 870 880 890
1220 1230 1240 1250 1260
pF1KE2 SFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSEL----ISYLTSPDVRSFIVGP
: :: ::: : ::::: .: . .: . . . . : . : . .::
XP_016 PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP
900 910 920 930 940 950
1270 1280 1290 1300 1310
pF1KE2 PGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGS----SYSSSMSTGG-----GG
:: ::.:::: . .. . . ... ....:. . :: .. . . : :
XP_016 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV
960 970 980 990 1000 1010
1320 1330 1340 1350 1360 1370
pF1KE2 AGSLGAGGAFGEAA--GDRGPYGT--DIGPGGGYGAAAEGGM--YAGNGGLLGADFAGDL
:. :. : :: . :.:: : : :: :: : .. :. . :. ::.:
XP_016 PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGP------
1020 1030 1040 1050 1060
1380 1390 1400 1410 1420
pF1KE2 DYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGIS----KVFSAYSNVTADLM
::: : : :::: :: : ::. .. . . .:
XP_016 ---------------QGL-PGENGPV-GPPGPPGQPGFPGLRGESPSMETLRRLIQEELG
1070 1080 1090 1100 1110
1430 1440 1450 1460 1470 1480
pF1KE2 DFFQT---YGAIQGPPG-QKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQV
..: : : ::. .:. .: ::: : : : ::. :: : :. :.
XP_016 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG
1120 1130 1140 1150 1160 1170
1490
pF1KE2 YAGRRRRRSIAVKP
XP_016 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHP
1180 1190 1200 1210 1220 1230
1497 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:21:26 2016 done: Sat Nov 5 22:21:29 2016
Total Scan time: 23.790 Total Display time: 0.550
Function used was FASTA [36.3.4 Apr, 2011]