Result of FASTA (ccds) for pF1KE4367
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4367, 386 aa
  1>>>pF1KE4367     386 - 386 aa - 386 aa
Library: human.CCDS.faa
  18921897 residues in 33420 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6811+/-0.00084; mu= 17.0173+/- 0.051
 mean_var=117.1051+/-22.797, 0's: 0 Z-trim(111.1): 36  B-trim: 53 in 1/51
 Lambda= 0.118519
 statistics sampled from 12213 (12242) to 12213 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.366), width:  16
 Scan time:  1.570

The best scores are:                                      opt bits E(33420)
CCDS6038.1 TNFRSF10D gene_id:8793|Hs109|chr8       ( 386) 2571 450.4 1.3e-126
CCDS6035.1 TNFRSF10B gene_id:8795|Hs109|chr8       ( 440) 1090 197.2 2.4e-50
CCDS6037.1 TNFRSF10C gene_id:8794|Hs109|chr8       ( 259)  819 150.6 1.5e-36
CCDS6036.1 TNFRSF10B gene_id:8795|Hs109|chr8       ( 411)  664 124.3   2e-28
CCDS6039.1 TNFRSF10A gene_id:8797|Hs109|chr8       ( 468)  632 118.9 9.6e-27


>>CCDS6038.1 TNFRSF10D gene_id:8793|Hs109|chr8            (386 aa)
 initn: 2571 init1: 2571 opt: 2571  Z-score: 2386.7  bits: 450.4 E(33420): 1.3e-126
Smith-Waterman score: 2571; 99.7% identity (99.7% similar) in 386 aa overlap (1-386:1-386)

               10        20        30        40        50        60
pF1KE4 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 QDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 QDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 KNESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 KNESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISYL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 KGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 KGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 AELTGVTVESPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLEEGHAKE
       ::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 AELTGVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLEEGHAKE
              310       320       330       340       350       360

              370       380      
pF1KE4 TIQDQLVGSEKLFYEEDEAGSATSCL
       ::::::::::::::::::::::::::
CCDS60 TIQDQLVGSEKLFYEEDEAGSATSCL
              370       380      

>>CCDS6035.1 TNFRSF10B gene_id:8795|Hs109|chr8            (440 aa)
 initn: 1035 init1: 582 opt: 1090  Z-score: 1017.4  bits: 197.2 E(33420): 2.4e-50
Smith-Waterman score: 1090; 53.0% identity (71.6% similar) in 345 aa overlap (5-342:5-336)

               10        20        30        40         50         
pF1KE4 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVA-VLLPVRVDSATIP
           ::..:.::.::  . :: : : :.::    :.. : .:..:: ::: : ..:: : 
CCDS60 MEQRGQNAPAASGARKRHGPGPREARGARP---GPRVPKTLVLVVAAVLLLVSAESALIT
               10        20        30           40        50       

      60        70        80        90       100       110         
pF1KE4 RQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCT
       .:: .::: .::::.: : .:  :: : : ::    :  :  : ::.   :.:  :: ::
CCDS60 QQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCT
        60        70        80        90       100       110       

     120       130       140       150       160       170         
pF1KE4 VCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIK
        : ::... : :::::.::::::.:.:....:::::: ::::::::::::..::: :::.
CCDS60 RCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIE
       120       130       140       150       160       170       

     180        190       200       210        220       230       
pF1KE4 C-KNESAASSTGKTPAAEETVTTILGMLASPYHYL-IIIVVLVIILAVVVVGFSCR----
       : ..::... .:..::.:::::.  :  :::     ::: : :  ....:. : :.    
CCDS60 CVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLW
       180       190       200       210       220       230       

           240       250       260       270       280       290   
pF1KE4 KKFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQ
       :: . ::::::::::: :::: :         :. ::::::. :: .:   :::::: ::
CCDS60 KKVLPYLKGICSGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQ
       240       250       260               270         280       

           300       310       320       330       340       350   
pF1KE4 EIQGQELAELTGVTVESPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATL
       :.. :: :: :::.. :: : ..::: ::::  ::::::::.:..: ..           
CCDS60 EMEVQEPAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFAD
       290       300       310       320       330       340       

           360       370       380                                 
pF1KE4 EEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL                           
                                                                   
CCDS60 LVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALE
       350       360       370       380       390       400       

>>CCDS6037.1 TNFRSF10C gene_id:8794|Hs109|chr8            (259 aa)
 initn: 907 init1: 680 opt: 819  Z-score: 769.8  bits: 150.6 E(33420): 1.5e-36
Smith-Waterman score: 819; 71.2% identity (85.3% similar) in 170 aa overlap (35-204:5-173)

           10        20        30        40        50        60    
pF1KE4 GQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPRQDEV
                                     :: ::::: :::::::: . :::  ::.::
CCDS60                           MARIPKTLKFVVVIVAVLLPVLAYSATTARQEEV
                                         10        20        30    

           70        80        90       100       110       120    
pF1KE4 PQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTVCKSG
       :::::::::::.:.: :::::::::::.:::::::::::::: :::: :::. :::::: 
CCDS60 PQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSD
           40        50        60        70        80        90    

          130       140       150       160       170       180    
pF1KE4 QTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKNES
       : .::::: ::::::::..:.:...::::::: : . :: : :.:::::  .::.: .: 
CCDS60 QKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKC-SRCPSGEVQVSNCTSWDDIQCVEEF
          100       110       120        130       140       150   

          190       200       210       220       230       240    
pF1KE4 AASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISYLKGIC
       .:..: .:::::::..:  :                                        
CCDS60 GANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETM
           160       170       180       190       200       210   

>>CCDS6036.1 TNFRSF10B gene_id:8795|Hs109|chr8            (411 aa)
 initn: 1028 init1: 575 opt: 664  Z-score: 624.1  bits: 124.3 E(33420): 2e-28
Smith-Waterman score: 980; 49.6% identity (67.3% similar) in 339 aa overlap (5-342:5-307)

               10        20        30        40         50         
pF1KE4 MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVA-VLLPVRVDSATIP
           ::..:.::.::  . :: : : :.::    :.. : .:..:: ::: : ..:: : 
CCDS60 MEQRGQNAPAASGARKRHGPGPREARGARP---GPRVPKTLVLVVAAVLLLVSAESALIT
               10        20        30           40        50       

      60        70        80        90       100       110         
pF1KE4 RQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCT
       .:: .::: .::::.: : .:  :: : : ::    :  :  : ::.   :.:  :: ::
CCDS60 QQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCT
        60        70        80        90       100       110       

     120       130       140       150       160       170         
pF1KE4 VCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIK
        : ::... : :::::.::::::.:.:....:::::: ::::::::::::..::: :::.
CCDS60 RCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIE
       120       130       140       150       160       170       

     180       190       200       210       220       230         
pF1KE4 CKNESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISY
       : .. ..               :.:         . ....:.:.:: :      :: . :
CCDS60 CVHKESG--------------IIIG---------VTVAAVVLIVAVFVCKSLLWKKVLPY
       180                              190       200       210    

     240       250       260       270       280       290         
pF1KE4 LKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQE
       :::::::::: :::: :         :. ::::::. :: .:   :::::: :::.. ::
CCDS60 LKGICSGGGGDPERVDR--------SSQRPGAEDNVLNEIVS--ILQPTQVPEQEMEVQE
          220       230               240         250       260    

     300       310       320       330       340       350         
pF1KE4 LAELTGVTVESPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLEEGHAK
        :: :::.. :: : ..::: ::::  ::::::::.:..: ..                 
CCDS60 PAEPTGVNMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDS
          270       280       290       300       310       320    

     360       370       380                                       
pF1KE4 ETIQDQLVGSEKLFYEEDEAGSATSCL                                 
                                                                   
CCDS60 WEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERL
          330       340       350       360       370       380    

>>CCDS6039.1 TNFRSF10A gene_id:8797|Hs109|chr8            (468 aa)
 initn: 1043 init1: 517 opt: 632  Z-score: 593.8  bits: 118.9 E(33420): 9.6e-27
Smith-Waterman score: 918; 44.2% identity (57.8% similar) in 443 aa overlap (5-384:60-466)

                                         10        20        30    
pF1KE4                           MGLWGQSVPTASSARAGRYPGARTASGTRPWLLD
                                     ::  :.:  ::::: :: : :  . : :  
CCDS60 AAATPSKVWGSSAGRIEPRGGGRGALPTSMGQHGPSAR-ARAGRAPGPRPAREASPRLRV
      30        40        50        60         70        80        

           40        50         60        70        80        90   
pF1KE4 PKILKFVVFIVAVLLPVRVDSA-TIPRQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYT
        : .::::  :.::: :  .:: ::  .:    :... :: ..:   : :: ::::::. 
CCDS60 HKTFKFVV--VGVLLQVVPSSAATIKLHD----QSIGTQQWEHSPLGELCPPGSHRSEHP
       90         100       110           120       130       140  

           100       110       120       130       140       150   
pF1KE4 GACNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPE
       :::: ::::: :: ::::: .:: ::.::: . ..: :::::.:.:::. :.:.. :: :
CCDS60 GACNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNSAE
            150       160       170       180       190       200  

           160       170       180       190       200       210   
pF1KE4 MCRTCRTGCPRGMVKVSNCTPRSDIKCKNESAASSTGKTPAAEETVTTILGMLASPYHYL
       ::: :  :::::::::..::: :::.: ..   :..:..                   ..
CCDS60 MCRKCSRGCPRGMVKVKDCTPWSDIECVHKE--SGNGHNI------------------WV
            210       220       230         240                    

           220       230       240       250       260       270   
pF1KE4 IIIVVLVIILAVVVVGFSCRKKFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAED
       :..:.::. : .:.: . :          : :: :: :. . :: : : .   : :::::
CCDS60 ILVVTLVVPLLLVAVLIVC--------CCIGSGCGGDPKCMDRVCFWRLGL-LRGPGAED
            250       260               270       280        290   

           280       290       300       310       320       330   
pF1KE4 NARNETLSNRYLQPTQVSEQEIQGQELAELTGVTVESPEEPQRLLEQAEAEGCQRRRLLV
       ::.:: :::     : ::::....:: :.::::::.:: : : ::  ::::: :::::::
CCDS60 NAHNEILSNADSLSTFVSEQQMESQEPADLTGVTVQSPGEAQCLLGPAEAEGSQRRRLLV
           300       310       320       330       340       350   

                                                                   
pF1KE4 PVNDAD------------------------------------------------------
       :.: ::                                                      
CCDS60 PANGADPTETLMLFFDKFANIVPFDSWDQLMRQLDLTKNEIDVVRAGTAGPGDALYAMLM
           360       370       380       390       400       410   

             340       350       360       370       380      
pF1KE4 --------SADISTLLDASATLEEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL
               .:.: :::::   .:: ::.: ::: :: : :..: :: .:::.:  
CCDS60 KWVNKTGRNASIHTLLDALERMEERHAREKIQDLLVDSGKFIYLEDGTGSAVSLE
           420       430       440       450       460        




386 residues in 1 query   sequences
18921897 residues in 33420 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:41:35 2019 done: Thu Oct 24 21:41:36 2019
 Total Scan time:  1.570 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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