FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6821, 379 aa
  1>>>pF1KE6821     379 - 379 aa - 379 aa
Library: /omim/omim.rfq.tfa
  65951994 residues in 93482 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4011+/-0.000346; mu= 16.0384+/- 0.021
 mean_var=70.6477+/-14.570, 0's: 0 Z-trim(115.4): 9  B-trim: 1785 in 2/52
 Lambda= 0.152590
 statistics sampled from 27007 (27012) to 27007 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.289), width:  16
 Scan time:  4.410

The best scores are:                                      opt bits E(93482)
NP_938023 (OMIM: 612374,615934) stimulator of inte ( 379) 2530 566.1 5.1e-161
XP_011535941 (OMIM: 612374,615934) stimulator of i ( 276) 1722 388.2 1.4e-107
NP_001288667 (OMIM: 612374,615934) stimulator of i ( 283) 1722 388.2 1.4e-107
NP_001354187 (OMIM: 612374,615934) stimulator of i ( 260) 1693 381.8 1.1e-105


>>NP_938023 (OMIM: 612374,615934) stimulator of interfer  (379 aa)
 initn: 2530 init1: 2530 opt: 2530  Z-score: 3012.5  bits: 566.1 E(93482): 5.1e-161
Smith-Waterman score: 2530; 100.0% identity (100.0% similar) in 379 aa overlap (1-379:1-379)

               10        20        30        40        50        60
pF1KE6 MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 NGVCSLAEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 NGVCSLAEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 LALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 TYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE6 SNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE6 DAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQE
              310       320       330       340       350       360

              370         
pF1KE6 PELLISGMEKPLPLRTDFS
       :::::::::::::::::::
NP_938 PELLISGMEKPLPLRTDFS
              370         

>>XP_011535941 (OMIM: 612374,615934) stimulator of inter  (276 aa)
 initn: 1722 init1: 1722 opt: 1722  Z-score: 2053.2  bits: 388.2 E(93482): 1.4e-107
Smith-Waterman score: 1722; 100.0% identity (100.0% similar) in 253 aa overlap (1-253:1-253)

               10        20        30        40        50        60
pF1KE6 MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 NGVCSLAEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGVCSLAEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 LALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 TYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE6 SNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILA
       :::::::::::::                                               
XP_011 SNSIYELLENGQRLPQTKAVRTSEGFMWVQGNPDQS                        
              250       260       270                              

>>NP_001288667 (OMIM: 612374,615934) stimulator of inter  (283 aa)
 initn: 1722 init1: 1722 opt: 1722  Z-score: 2053.0  bits: 388.2 E(93482): 1.4e-107
Smith-Waterman score: 1722; 100.0% identity (100.0% similar) in 253 aa overlap (1-253:1-253)

               10        20        30        40        50        60
pF1KE6 MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 NGVCSLAEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGVCSLAEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 LALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 TYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE6 SNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILA
       :::::::::::::                                               
NP_001 SNSIYELLENGQRNLQMTAASRCPRRFSGTCGRRKRKRLLWAA                 
              250       260       270       280                    

>>NP_001354187 (OMIM: 612374,615934) stimulator of inter  (260 aa)
 initn: 1693 init1: 1693 opt: 1693  Z-score: 2019.1  bits: 381.8 E(93482): 1.1e-105
Smith-Waterman score: 1693; 100.0% identity (100.0% similar) in 260 aa overlap (120-379:1-260)

      90       100       110       120       130       140         
pF1KE6 GCPLRRGALLLLSIYFYYSLPNAVGPPFTWMLALLGLSQALNILLGLKGLAPAEISAVCE
                                     ::::::::::::::::::::::::::::::
NP_001                               MLALLGLSQALNILLGLKGLAPAEISAVCE
                                             10        20        30

     150       160       170       180       190       200         
pF1KE6 KGNFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVP
               40        50        60        70        80        90

     210       220       230       240       250       260         
pF1KE6 DNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLF
              100       110       120       130       140       150

     270       280       290       300       310       320         
pF1KE6 AMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEV
              160       170       180       190       200       210

     330       340       350       360       370         
pF1KE6 LRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDFS
              220       230       240       250       260




379 residues in 1 query   sequences
65951994 residues in 93482 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Jun 19 14:31:58 2019 done: Wed Jun 19 14:31:59 2019
 Total Scan time:  4.410 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]