Result of FASTA (omim) for pF1KE2508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2508, 454 aa
  1>>>pF1KE2508     454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
  64369986 residues in 92320 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.5193+/-0.000374; mu= 9.7640+/- 0.024
 mean_var=217.1857+/-46.625, 0's: 0 Z-trim(119.0): 140  B-trim: 942 in 1/54
 Lambda= 0.087028
 statistics sampled from 33786 (33941) to 33786 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.368), width:  16
 Scan time:  4.560

The best scores are:                                      opt bits E(92320)
NP_852556 (OMIM: 171833,269880,615214,616005) phos ( 454) 3027 393.0 9.6e-109
XP_011541795 (OMIM: 171833,269880,615214,616005) p ( 615) 2788 363.1 1.3e-99
XP_016865075 (OMIM: 171833,269880,615214,616005) p ( 633) 2788 363.1 1.3e-99
XP_005248599 (OMIM: 171833,269880,615214,616005) p ( 724) 2788 363.2 1.4e-99
NP_852664 (OMIM: 171833,269880,615214,616005) phos ( 724) 2788 363.2 1.4e-99
XP_016865074 (OMIM: 171833,269880,615214,616005) p ( 724) 2788 363.2 1.4e-99
NP_852665 (OMIM: 171833,269880,615214,616005) phos ( 424) 2771 360.8 4.3e-99
NP_001229395 (OMIM: 171833,269880,615214,616005) p ( 361) 2379 311.5 2.6e-84
NP_001107644 (OMIM: 606076) phosphatidylinositol 3 ( 461) 2374 311.0 4.6e-84
NP_003620 (OMIM: 606076) phosphatidylinositol 3-ki ( 461) 2374 311.0 4.6e-84
NP_001290357 (OMIM: 606076) phosphatidylinositol 3 ( 478) 2374 311.0 4.7e-84
NP_001315577 (OMIM: 606076) phosphatidylinositol 3 ( 417) 2185 287.2   6e-77
NP_001315579 (OMIM: 606076) phosphatidylinositol 3 ( 417) 2185 287.2   6e-77
NP_001315580 (OMIM: 606076) phosphatidylinositol 3 ( 417) 2185 287.2   6e-77
NP_001315578 (OMIM: 606076) phosphatidylinositol 3 ( 417) 2185 287.2   6e-77
NP_005018 (OMIM: 603157,603387) phosphatidylinosit ( 728) 2187 287.8 7.3e-77
NP_001315582 (OMIM: 606076) phosphatidylinositol 3 ( 380) 2008 265.0 2.8e-70
NP_001315581 (OMIM: 606076) phosphatidylinositol 3 ( 404) 1773 235.5 2.2e-61
NP_001315583 (OMIM: 606076) phosphatidylinositol 3 ( 305) 1557 208.2 2.7e-53
NP_001290358 (OMIM: 606076) phosphatidylinositol 3 ( 402) 1388 187.1 7.8e-47


>>NP_852556 (OMIM: 171833,269880,615214,616005) phosphat  (454 aa)
 initn: 3027 init1: 3027 opt: 3027  Z-score: 2073.9  bits: 393.0 E(92320): 9.6e-109
Smith-Waterman score: 3027; 99.8% identity (100.0% similar) in 454 aa overlap (1-454:1-454)

               10        20        30        40        50        60
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 KYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
              370       380       390       400       410       420

              430       440       450    
pF1KE2 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       ::::::::::::::::::::::::::::::::::
NP_852 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
              430       440       450    

>>XP_011541795 (OMIM: 171833,269880,615214,616005) phosp  (615 aa)
 initn: 2786 init1: 2786 opt: 2788  Z-score: 1910.2  bits: 363.1 E(92320): 1.3e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:191-615)

               10        20        30         40        50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
                                     : .: :::::::::::::::::::::::::
XP_011 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
              170       180       190       200       210       220

      60        70        80        90       100       110         
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
              230       240       250       260       270       280

     120       130       140       150       160       170         
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
              290       300       310       320       330       340

     180       190       200       210       220       230         
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
              350       360       370       380       390       400

     240       250       260       270       280       290         
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
              410       420       430       440       450       460

     300       310       320       330       340       350         
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
              470       480       490       500       510       520

     360       370       380       390       400       410         
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
              530       540       550       560       570       580

     420       430       440       450    
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       :::::::::::::::::::::::::::::::::::
XP_011 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
              590       600       610     

>>XP_016865075 (OMIM: 171833,269880,615214,616005) phosp  (633 aa)
 initn: 2786 init1: 2786 opt: 2788  Z-score: 1910.1  bits: 363.1 E(92320): 1.3e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:209-633)

               10        20        30         40        50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
                                     : .: :::::::::::::::::::::::::
XP_016 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
      180       190       200       210       220       230        

      60        70        80        90       100       110         
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
      240       250       260       270       280       290        

     120       130       140       150       160       170         
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
      300       310       320       330       340       350        

     180       190       200       210       220       230         
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
      360       370       380       390       400       410        

     240       250       260       270       280       290         
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
      420       430       440       450       460       470        

     300       310       320       330       340       350         
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
      480       490       500       510       520       530        

     360       370       380       390       400       410         
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
      540       550       560       570       580       590        

     420       430       440       450    
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       :::::::::::::::::::::::::::::::::::
XP_016 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
      600       610       620       630   

>>XP_005248599 (OMIM: 171833,269880,615214,616005) phosp  (724 aa)
 initn: 2786 init1: 2786 opt: 2788  Z-score: 1909.4  bits: 363.2 E(92320): 1.4e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:300-724)

               10        20        30         40        50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
                                     : .: :::::::::::::::::::::::::
XP_005 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
     270       280       290       300       310       320         

      60        70        80        90       100       110         
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
     330       340       350       360       370       380         

     120       130       140       150       160       170         
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
     390       400       410       420       430       440         

     180       190       200       210       220       230         
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
     450       460       470       480       490       500         

     240       250       260       270       280       290         
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
     510       520       530       540       550       560         

     300       310       320       330       340       350         
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
     570       580       590       600       610       620         

     360       370       380       390       400       410         
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
     630       640       650       660       670       680         

     420       430       440       450    
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       :::::::::::::::::::::::::::::::::::
XP_005 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
     690       700       710       720    

>>NP_852664 (OMIM: 171833,269880,615214,616005) phosphat  (724 aa)
 initn: 2786 init1: 2786 opt: 2788  Z-score: 1909.4  bits: 363.2 E(92320): 1.4e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:300-724)

               10        20        30         40        50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
                                     : .: :::::::::::::::::::::::::
NP_852 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
     270       280       290       300       310       320         

      60        70        80        90       100       110         
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
     330       340       350       360       370       380         

     120       130       140       150       160       170         
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
     390       400       410       420       430       440         

     180       190       200       210       220       230         
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
     450       460       470       480       490       500         

     240       250       260       270       280       290         
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
     510       520       530       540       550       560         

     300       310       320       330       340       350         
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
     570       580       590       600       610       620         

     360       370       380       390       400       410         
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
     630       640       650       660       670       680         

     420       430       440       450    
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       :::::::::::::::::::::::::::::::::::
NP_852 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
     690       700       710       720    

>>XP_016865074 (OMIM: 171833,269880,615214,616005) phosp  (724 aa)
 initn: 2786 init1: 2786 opt: 2788  Z-score: 1909.4  bits: 363.2 E(92320): 1.4e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:300-724)

               10        20        30         40        50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
                                     : .: :::::::::::::::::::::::::
XP_016 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
     270       280       290       300       310       320         

      60        70        80        90       100       110         
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
     330       340       350       360       370       380         

     120       130       140       150       160       170         
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
     390       400       410       420       430       440         

     180       190       200       210       220       230         
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
     450       460       470       480       490       500         

     240       250       260       270       280       290         
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
     510       520       530       540       550       560         

     300       310       320       330       340       350         
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
     570       580       590       600       610       620         

     360       370       380       390       400       410         
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
     630       640       650       660       670       680         

     420       430       440       450    
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       :::::::::::::::::::::::::::::::::::
XP_016 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
     690       700       710       720    

>>NP_852665 (OMIM: 171833,269880,615214,616005) phosphat  (424 aa)
 initn: 2771 init1: 2771 opt: 2771  Z-score: 1900.6  bits: 360.8 E(92320): 4.3e-99
Smith-Waterman score: 2771; 99.8% identity (100.0% similar) in 418 aa overlap (37-454:7-424)

         10        20        30        40        50        60      
pF1KE2 NMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQDAEWYWG
                                     ::::::::::::::::::::::::::::::
NP_852                         MHNLQTLPPKPPKPTTVANNGMNNNMSLQDAEWYWG
                                       10        20        30      

         70        80        90       100       110       120      
pF1KE2 DISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 DISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPL
         40        50        60        70        80        90      

        130       140       150       160       170       180      
pF1KE2 TFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYNTQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_852 TFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQF
        100       110       120       130       140       150      

        190       200       210       220       230       240      
pF1KE2 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG
        160       170       180       190       200       210      

        250       260       270       280       290       300      
pF1KE2 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKT
        220       230       240       250       260       270      

        310       320       330       340       350       360      
pF1KE2 RDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 RDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAEN
        280       290       300       310       320       330      

        370       380       390       400       410       420      
pF1KE2 LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVL
        340       350       360       370       380       390      

        430       440       450    
pF1KE2 HYQHTSLVQHNDSLNVTLAYPVYAQQRR
       ::::::::::::::::::::::::::::
NP_852 HYQHTSLVQHNDSLNVTLAYPVYAQQRR
        400       410       420    

>>NP_001229395 (OMIM: 171833,269880,615214,616005) phosp  (361 aa)
 initn: 2379 init1: 2379 opt: 2379  Z-score: 1635.4  bits: 311.5 E(92320): 2.6e-84
Smith-Waterman score: 2379; 99.7% identity (100.0% similar) in 361 aa overlap (94-454:1-361)

            70        80        90       100       110       120   
pF1KE2 YWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
                                     ::::::::::::::::::::::::::::::
NP_001                               MHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
                                             10        20        30

           130       140       150       160       170       180   
pF1KE2 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYN
               40        50        60        70        80        90

           190       200       210       220       230       240   
pF1KE2 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
              100       110       120       130       140       150

           250       260       270       280       290       300   
pF1KE2 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
              160       170       180       190       200       210

           310       320       330       340       350       360   
pF1KE2 RKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNK
              220       230       240       250       260       270

           370       380       390       400       410       420   
pF1KE2 AENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKE
              280       290       300       310       320       330

           430       440       450    
pF1KE2 LVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
       :::::::::::::::::::::::::::::::
NP_001 LVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
              340       350       360 

>>NP_001107644 (OMIM: 606076) phosphatidylinositol 3-kin  (461 aa)
 initn: 1576 init1: 1576 opt: 2374  Z-score: 1630.8  bits: 311.0 E(92320): 4.6e-84
Smith-Waterman score: 2374; 77.8% identity (92.5% similar) in 455 aa overlap (1-451:1-455)

               10        20        30        40         50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL
       ::::::.:.  : .. .. .  .:.:.::::::::::::::::: : :  ::: ....::
NP_001 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KE2 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
       ::::::::::::::::.::::  :::::::::::::.::::::::::::::::::.::::
NP_001 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KE2 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
       ::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
NP_001 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KE2 LHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
       :..:..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
NP_001 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KE2 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
       ::.:.::::::::.::: ::::::::..:: ::. :::.:::.:: . :::::.::::::
NP_001 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP
              250       260       270       280       290       300

      300       310       320         330       340       350      
pF1KE2 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
       ::::::: :::.:.::..::::::.:: :::  ::.....: . :.::.:::.::::: :
NP_001 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
        . :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
NP_001 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
              370       380       390       400       410       420

        420       430       440       450       
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR   
       :::::::::::::.:::::::::::: :::::.::      
NP_001 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
              430       440       450       460 

>>NP_003620 (OMIM: 606076) phosphatidylinositol 3-kinase  (461 aa)
 initn: 1576 init1: 1576 opt: 2374  Z-score: 1630.8  bits: 311.0 E(92320): 4.6e-84
Smith-Waterman score: 2374; 77.8% identity (92.5% similar) in 455 aa overlap (1-451:1-455)

               10        20        30        40         50         
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL
       ::::::.:.  : .. .. .  .:.:.::::::::::::::::: : :  ::: ....::
NP_003 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KE2 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
       ::::::::::::::::.::::  :::::::::::::.::::::::::::::::::.::::
NP_003 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KE2 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
       ::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
NP_003 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KE2 LHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
       :..:..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
NP_003 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KE2 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
       ::.:.::::::::.::: ::::::::..:: ::. :::.:::.:: . :::::.::::::
NP_003 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP
              250       260       270       280       290       300

      300       310       320         330       340       350      
pF1KE2 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
       ::::::: :::.:.::..::::::.:: :::  ::.....: . :.::.:::.::::: :
NP_003 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
              310       320       330       340       350       360

        360       370       380       390       400       410      
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
        . :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
NP_003 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
              370       380       390       400       410       420

        420       430       440       450       
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR   
       :::::::::::::.:::::::::::: :::::.::      
NP_003 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
              430       440       450       460 




454 residues in 1 query   sequences
64369986 residues in 92320 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:39:44 2019 done: Thu Oct 24 21:39:45 2019
 Total Scan time:  4.560 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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