Result of FASTA (omim) for
pF1KE3718
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3718, 2471 aa
1>>>pF1KE3718 2471 - 2471 aa - 2471 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.2879+/-0.000689; mu= -5.6560+/- 0.043
mean_var=663.6531+/-141.290, 0's: 0 Z-trim(117.9): 706 B-trim: 309 in 1/57
Lambda= 0.049786
statistics sampled from 29523 (30281) to 29523 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.355), width: 16
Scan time: 18.800
The best scores are: opt bits E(85289)
NP_077719 (OMIM: 102500,600275,610205) neurogenic (2471) 18249 1329.1 0
XP_016856861 (OMIM: 102500,600275,610205) PREDICTE (2455) 18075 1316.6 0
XP_011539821 (OMIM: 102500,600275,610205) PREDICTE (2467) 18069 1316.2 0
XP_005270958 (OMIM: 102500,600275,610205) PREDICTE (2432) 17953 1307.9 0
XP_011539822 (OMIM: 102500,600275,610205) PREDICTE (2432) 17953 1307.9 0
XP_016856862 (OMIM: 102500,600275,610205) PREDICTE (2432) 17953 1307.9 0
NP_001186930 (OMIM: 102500,600275,610205) neurogen (1235) 9522 701.9 1.3e-200
NP_060087 (OMIM: 109730,190198,616028) neurogenic (2555) 6850 510.4 1.2e-142
XP_011517019 (OMIM: 109730,190198,616028) PREDICTE (2314) 6009 449.9 1.7e-124
NP_000426 (OMIM: 125310,130720,600276,615293) neur (2321) 5232 394.1 1.1e-107
XP_005259981 (OMIM: 125310,130720,600276,615293) P (2269) 4395 334.0 1.4e-89
NP_004548 (OMIM: 164951) neurogenic locus notch ho (2003) 3253 251.9 6.2e-65
NP_001136272 (OMIM: 602772,612424) protein eyes sh (3144) 1714 141.6 1.5e-31
NP_001278938 (OMIM: 602772,612424) protein eyes sh (3165) 1714 141.6 1.5e-31
XP_016883196 (OMIM: 118450,187500,601920) PREDICTE (1059) 1395 118.1 6.3e-25
NP_000205 (OMIM: 118450,187500,601920) protein jag (1218) 1395 118.2 6.8e-25
XP_016882862 (OMIM: 608529) PREDICTED: fibrillin-3 (2789) 1248 108.1 1.7e-21
XP_011509239 (OMIM: 616634) PREDICTED: sushi, nido ( 905) 1229 106.1 2.2e-21
XP_016859265 (OMIM: 616634) PREDICTED: sushi, nido (1420) 1227 106.2 3.2e-21
NP_002217 (OMIM: 602570) protein jagged-2 isoform (1238) 1209 104.8 7.2e-21
NP_660142 (OMIM: 602570) protein jagged-2 isoform (1200) 1179 102.7 3.2e-20
XP_016882864 (OMIM: 608529) PREDICTED: fibrillin-3 (2768) 1178 103.1 5.5e-20
XP_016882867 (OMIM: 608529) PREDICTED: fibrillin-3 (1595) 1168 102.0 6.5e-20
XP_016882866 (OMIM: 608529) PREDICTED: fibrillin-3 (1948) 1168 102.1 7.4e-20
XP_016882863 (OMIM: 608529) PREDICTED: fibrillin-3 (2777) 1168 102.3 9.1e-20
NP_001308360 (OMIM: 608529) fibrillin-3 precursor (2809) 1168 102.3 9.2e-20
XP_016882861 (OMIM: 608529) PREDICTED: fibrillin-3 (2809) 1168 102.3 9.2e-20
NP_115823 (OMIM: 608529) fibrillin-3 precursor [Ho (2809) 1168 102.3 9.2e-20
XP_016882868 (OMIM: 608529) PREDICTED: fibrillin-3 (2851) 1168 102.4 9.3e-20
NP_001244895 (OMIM: 172870,600105,604210,613835) p ( 870) 1114 97.8 6.6e-19
XP_011507669 (OMIM: 172870,600105,604210,613835) P (1297) 1100 97.0 1.7e-18
XP_011507667 (OMIM: 172870,600105,604210,613835) P (1349) 1100 97.0 1.7e-18
NP_957705 (OMIM: 172870,600105,604210,613835) prot (1406) 1100 97.1 1.8e-18
XP_016856341 (OMIM: 172870,600105,604210,613835) P (1451) 1100 97.1 1.8e-18
XP_011539189 (OMIM: 604266) PREDICTED: multiple ep (1395) 1081 95.7 4.6e-18
NP_620711 (OMIM: 607299) delta and Notch-like epid ( 737) 1069 94.5 5.6e-18
XP_016882865 (OMIM: 608529) PREDICTED: fibrillin-3 (2766) 1076 95.7 8.9e-18
NP_699197 (OMIM: 611691) sushi, von Willebrand fac (3571) 1027 92.4 1.2e-16
NP_001244894 (OMIM: 172870,600105,604210,613835) p (1382) 1013 90.8 1.3e-16
XP_011516858 (OMIM: 219730,609720,616220) PREDICTE (1276) 966 87.4 1.3e-15
NP_775960 (OMIM: 219730,609720,616220) protein cru (1285) 966 87.4 1.3e-15
NP_005609 (OMIM: 606582) delta-like protein 1 prec ( 723) 954 86.2 1.7e-15
NP_061947 (OMIM: 605185,616589) delta-like protein ( 685) 933 84.7 4.7e-15
XP_011516859 (OMIM: 219730,609720,616220) PREDICTE (1220) 936 85.2 5.7e-15
XP_011516860 (OMIM: 219730,609720,616220) PREDICTE (1220) 936 85.2 5.7e-15
XP_016878162 (OMIM: 612454) PREDICTED: multiple ep (1021) 895 82.2 4e-14
NP_115821 (OMIM: 612454) multiple epidermal growth (1044) 895 82.2 4e-14
XP_016878161 (OMIM: 612454) PREDICTED: multiple ep (1044) 895 82.2 4e-14
XP_016878160 (OMIM: 612454) PREDICTED: multiple ep (1092) 895 82.2 4.1e-14
XP_016864717 (OMIM: 121050,612570,616118) PREDICTE (2861) 899 83.0 6.1e-14
>>NP_077719 (OMIM: 102500,600275,610205) neurogenic locu (2471 aa)
initn: 18249 init1: 18249 opt: 18249 Z-score: 7106.8 bits: 1329.1 E(85289): 0
Smith-Waterman score: 18249; 100.0% identity (100.0% similar) in 2471 aa overlap (1-2471:1-2471)
10 20 30 40 50 60
pF1KE3 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 CTCKKGFKGYNCQVNIDECASNPCLNQGTCSDDISGYTCHCVLPYTGKNCQTVLAPCSPN
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_077 CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE3 DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE3 LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE3 HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE3 KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE3 VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE3 VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE3 GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE3 QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE3 TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
2410 2420 2430 2440 2450 2460
2470
pF1KE3 EPPHNNMQVYA
:::::::::::
NP_077 EPPHNNMQVYA
2470
>>XP_016856861 (OMIM: 102500,600275,610205) PREDICTED: n (2455 aa)
initn: 18069 init1: 18069 opt: 18075 Z-score: 7039.3 bits: 1316.6 E(85289): 0
Smith-Waterman score: 18075; 99.7% identity (99.8% similar) in 2455 aa overlap (17-2471:1-2455)
10 20 30 40 50 60
pF1KE3 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
.: . .::::::::::::::::::::::::::::::::::::
XP_016 MCFTLLHKALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
10 20 30 40
70 80 90 100 110 120
pF1KE3 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE3 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE3 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE3 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE3 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE3 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE3 CTCKKGFKGYNCQVNIDECASNPCLNQGTCSDDISGYTCHCVLPYTGKNCQTVLAPCSPN
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_016 CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE3 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE3 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE3 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE3 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE3 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE3 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE3 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE3 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE3 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KE3 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KE3 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KE3 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KE3 DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE3 SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KE3 LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KE3 SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KE3 RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KE3 DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KE3 DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KE3 LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KE3 HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KE3 KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY
2090 2100 2110 2120 2130 2140
2170 2180 2190 2200 2210 2220
pF1KE3 VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS
2150 2160 2170 2180 2190 2200
2230 2240 2250 2260 2270 2280
pF1KE3 VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP
2210 2220 2230 2240 2250 2260
2290 2300 2310 2320 2330 2340
pF1KE3 GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY
2270 2280 2290 2300 2310 2320
2350 2360 2370 2380 2390 2400
pF1KE3 QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
2330 2340 2350 2360 2370 2380
2410 2420 2430 2440 2450 2460
pF1KE3 TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
2390 2400 2410 2420 2430 2440
2470
pF1KE3 EPPHNNMQVYA
:::::::::::
XP_016 EPPHNNMQVYA
2450
>>XP_011539821 (OMIM: 102500,600275,610205) PREDICTED: n (2467 aa)
initn: 18069 init1: 18069 opt: 18069 Z-score: 7037.0 bits: 1316.2 E(85289): 0
Smith-Waterman score: 18069; 100.0% identity (100.0% similar) in 2447 aa overlap (25-2471:21-2467)
10 20 30 40 50 60
pF1KE3 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
::::::::::::::::::::::::::::::::::::
XP_011 MNTYLVSAVSLRCVSVERYKALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE3 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE3 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE3 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE3 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE3 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE3 CTCKKGFKGYNCQVNIDECASNPCLNQGTCSDDISGYTCHCVLPYTGKNCQTVLAPCSPN
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_011 CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE3 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE3 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE3 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE3 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE3 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE3 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE3 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE3 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE3 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE3 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE3 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNS
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE3 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQ
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE3 DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAG
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE3 SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLY
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE3 LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNL
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE3 SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIR
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE3 RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIIT
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KE3 DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAA
1860 1870 1880 1890 1900 1910
1930 1940 1950 1960 1970 1980
pF1KE3 DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSA
1920 1930 1940 1950 1960 1970
1990 2000 2010 2020 2030 2040
pF1KE3 LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITD
1980 1990 2000 2010 2020 2030
2050 2060 2070 2080 2090 2100
pF1KE3 HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG
2040 2050 2060 2070 2080 2090
2110 2120 2130 2140 2150 2160
pF1KE3 KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTY
2100 2110 2120 2130 2140 2150
2170 2180 2190 2200 2210 2220
pF1KE3 VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPS
2160 2170 2180 2190 2200 2210
2230 2240 2250 2260 2270 2280
pF1KE3 VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHP
2220 2230 2240 2250 2260 2270
2290 2300 2310 2320 2330 2340
pF1KE3 GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMY
2280 2290 2300 2310 2320 2330
2350 2360 2370 2380 2390 2400
pF1KE3 QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAER
2340 2350 2360 2370 2380 2390
2410 2420 2430 2440 2450 2460
pF1KE3 TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMS
2400 2410 2420 2430 2440 2450
2470
pF1KE3 EPPHNNMQVYA
:::::::::::
XP_011 EPPHNNMQVYA
2460
>>XP_005270958 (OMIM: 102500,600275,610205) PREDICTED: n (2432 aa)
initn: 17953 init1: 17953 opt: 17953 Z-score: 6992.0 bits: 1307.9 E(85289): 0
Smith-Waterman score: 17953; 100.0% identity (100.0% similar) in 2432 aa overlap (40-2471:1-2432)
10 20 30 40 50 60
pF1KE3 WALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCE
::::::::::::::::::::::::::::::
XP_005 MCVTYHNGTGYCKCPEGFLGEYCQHRDPCE
10 20 30
70 80 90 100 110 120
pF1KE3 KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 ECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 PGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE3 GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEH
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE3 AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE3 HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE3 HPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQID
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE3 ECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCV
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE3 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPC
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE3 IHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKG
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE3 YNCQVNIDECASNPCLNQGTCSDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_005 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE3 ESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE3 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE3 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE3 SSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLC
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE3 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE3 LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE3 KCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE3 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE3 ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSC
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE3 HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQ
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KE3 WDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYC
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE3 ADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRAL
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE3 GTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAGSKVFLEIDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAGSKVFLEIDN
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE3 RQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLYLLAVAVVII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLYLLAVAVVII
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE3 LFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNLSVQVSEANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNLSVQVSEANL
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE3 IGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTP
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KE3 PQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIITDLVYQGASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIITDLVYQGASL
1780 1790 1800 1810 1820 1830
1870 1880 1890 1900 1910 1920
pF1KE3 QAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQIL
1840 1850 1860 1870 1880 1890
1930 1940 1950 1960 1970 1980
pF1KE3 IRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNN
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KE3 VEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDV
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090 2100
pF1KE3 ARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMGKKSRRPSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMGKKSRRPSAK
2020 2030 2040 2050 2060 2070
2110 2120 2130 2140 2150 2160
pF1KE3 STMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPM
2080 2090 2100 2110 2120 2130
2170 2180 2190 2200 2210 2220
pF1KE3 ITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHH
2140 2150 2160 2170 2180 2190
2230 2240 2250 2260 2270 2280
pF1KE3 IVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHPGIAPQSRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHPGIAPQSRPP
2200 2210 2220 2230 2240 2250
2290 2300 2310 2320 2330 2340
pF1KE3 EGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMARLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMARLP
2260 2270 2280 2290 2300 2310
2350 2360 2370 2380 2390 2400
pF1KE3 SVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQ
2320 2330 2340 2350 2360 2370
2410 2420 2430 2440 2450 2460
pF1KE3 GEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPHNNMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPHNNMQV
2380 2390 2400 2410 2420 2430
2470
pF1KE3 YA
::
XP_005 YA
>>XP_011539822 (OMIM: 102500,600275,610205) PREDICTED: n (2432 aa)
initn: 17953 init1: 17953 opt: 17953 Z-score: 6992.0 bits: 1307.9 E(85289): 0
Smith-Waterman score: 17953; 100.0% identity (100.0% similar) in 2432 aa overlap (40-2471:1-2432)
10 20 30 40 50 60
pF1KE3 WALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCE
::::::::::::::::::::::::::::::
XP_011 MCVTYHNGTGYCKCPEGFLGEYCQHRDPCE
10 20 30
70 80 90 100 110 120
pF1KE3 KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 ECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 PGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE3 GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEH
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE3 AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE3 HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE3 HPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQID
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE3 ECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCV
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE3 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPC
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE3 IHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKG
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE3 YNCQVNIDECASNPCLNQGTCSDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE3 ESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE3 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE3 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE3 SSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLC
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE3 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE3 LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE3 KCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE3 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE3 ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSC
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE3 HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQ
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KE3 WDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYC
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE3 ADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRAL
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE3 GTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAGSKVFLEIDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAGSKVFLEIDN
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE3 RQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLYLLAVAVVII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLYLLAVAVVII
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE3 LFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNLSVQVSEANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNLSVQVSEANL
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE3 IGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTP
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KE3 PQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIITDLVYQGASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIITDLVYQGASL
1780 1790 1800 1810 1820 1830
1870 1880 1890 1900 1910 1920
pF1KE3 QAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQIL
1840 1850 1860 1870 1880 1890
1930 1940 1950 1960 1970 1980
pF1KE3 IRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNN
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KE3 VEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDV
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090 2100
pF1KE3 ARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMGKKSRRPSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMGKKSRRPSAK
2020 2030 2040 2050 2060 2070
2110 2120 2130 2140 2150 2160
pF1KE3 STMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPM
2080 2090 2100 2110 2120 2130
2170 2180 2190 2200 2210 2220
pF1KE3 ITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHH
2140 2150 2160 2170 2180 2190
2230 2240 2250 2260 2270 2280
pF1KE3 IVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHPGIAPQSRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHPGIAPQSRPP
2200 2210 2220 2230 2240 2250
2290 2300 2310 2320 2330 2340
pF1KE3 EGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMARLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMARLP
2260 2270 2280 2290 2300 2310
2350 2360 2370 2380 2390 2400
pF1KE3 SVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQ
2320 2330 2340 2350 2360 2370
2410 2420 2430 2440 2450 2460
pF1KE3 GEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPHNNMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPHNNMQV
2380 2390 2400 2410 2420 2430
2470
pF1KE3 YA
::
XP_011 YA
>>XP_016856862 (OMIM: 102500,600275,610205) PREDICTED: n (2432 aa)
initn: 17953 init1: 17953 opt: 17953 Z-score: 6992.0 bits: 1307.9 E(85289): 0
Smith-Waterman score: 17953; 100.0% identity (100.0% similar) in 2432 aa overlap (40-2471:1-2432)
10 20 30 40 50 60
pF1KE3 WALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCE
::::::::::::::::::::::::::::::
XP_016 MCVTYHNGTGYCKCPEGFLGEYCQHRDPCE
10 20 30
70 80 90 100 110 120
pF1KE3 KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTY
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 ECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 PGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNAC
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE3 GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEH
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE3 AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE3 HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE3 HPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQID
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE3 ECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCV
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE3 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPC
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE3 IHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKG
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE3 YNCQVNIDECASNPCLNQGTCSDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 YNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCK
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE3 ESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE3 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVN
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE3 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINEC
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE3 SSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLC
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE3 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQ
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE3 LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHF
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE3 KCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECL
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE3 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGF
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE3 ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSC
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE3 HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQ
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KE3 WDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYC
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE3 ADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRAL
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE3 GTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAGSKVFLEIDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAGSKVFLEIDN
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE3 RQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLYLLAVAVVII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQCVQDSDHCFKNTDAAAALLASHAIQGTLSYPLVSVVSESLTPERTQLLYLLAVAVVII
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE3 LFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNLSVQVSEANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFIILLGVIMAKRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDAVGLKNLSVQVSEANL
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE3 IGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTP
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KE3 PQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIITDLVYQGASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDSSANIITDLVYQGASL
1780 1790 1800 1810 1820 1830
1870 1880 1890 1900 1910 1920
pF1KE3 QAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQIL
1840 1850 1860 1870 1880 1890
1930 1940 1950 1960 1970 1980
pF1KE3 IRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNN
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KE3 VEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDV
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090 2100
pF1KE3 ARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMGKKSRRPSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMGKKSRRPSAK
2020 2030 2040 2050 2060 2070
2110 2120 2130 2140 2150 2160
pF1KE3 STMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPM
2080 2090 2100 2110 2120 2130
2170 2180 2190 2200 2210 2220
pF1KE3 ITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITSPGILQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHH
2140 2150 2160 2170 2180 2190
2230 2240 2250 2260 2270 2280
pF1KE3 IVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHPGIAPQSRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHPGIAPQSRPP
2200 2210 2220 2230 2240 2250
2290 2300 2310 2320 2330 2340
pF1KE3 EGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMARLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMARLP
2260 2270 2280 2290 2300 2310
2350 2360 2370 2380 2390 2400
pF1KE3 SVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQ
2320 2330 2340 2350 2360 2370
2410 2420 2430 2440 2450 2460
pF1KE3 GEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPHNNMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPGTHMSEPPHNNMQV
2380 2390 2400 2410 2420 2430
2470
pF1KE3 YA
::
XP_016 YA
>>NP_001186930 (OMIM: 102500,600275,610205) neurogenic l (1235 aa)
initn: 10447 init1: 9519 opt: 9522 Z-score: 3722.5 bits: 701.9 E(85289): 1.3e-200
Smith-Waterman score: 9522; 98.9% identity (99.1% similar) in 1236 aa overlap (1-1236:1-1233)
10 20 30 40 50 60
pF1KE3 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 CTCKKGFKGYNCQVNIDECASNPCLNQGTCSDDISGYTCHCVLPYTGKNCQTVLAPCSPN
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_001 CTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER
:::::::::::::::::::. .: . :::
NP_001 TCIDLVNHFKCSCPPGTRGMKSSLSI---FHPGHCLKL
1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE3 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA
>>NP_060087 (OMIM: 109730,190198,616028) neurogenic locu (2555 aa)
initn: 7355 init1: 4381 opt: 6850 Z-score: 2681.9 bits: 510.4 E(85289): 1.2e-142
Smith-Waterman score: 9945; 53.7% identity (74.2% similar) in 2522 aa overlap (6-2403:2-2499)
10 20 30 40 50 60
pF1KE3 MPALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGE
: :: :: : : : :.. .: . : :.: : : ::: : : .:.:
NP_060 MPPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKC-EAANGTEACVCGGAFVGP
10 20 30 40 50
70 80 90 100 110
pF1KE3 YCQHRDPCEKNRCQNGGTC--VAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNG
:: .:: .. :.:.::: : . .. .: :: ::.: : .. :. . :: ::
NP_060 RCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACL-TNPCRNG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQK
::: .:. :.: : :..:: :: .: : :.:::::. : .. :.: .: :
NP_060 GTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 CETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCR
:. ::::: . :: :.::::: : :::.: : :: :. ::::.:::: ::::::
NP_060 CRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 QTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTE
::: : :: ::::: :..::.::::::.. :.:::.::::::::::::::.::::.:::
NP_060 PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 DVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV
::::: :.:::::::::: : .:::.:::::::.:.:::::::::: :.: :.:: :::
NP_060 DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 ASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVD
::: : ::.:..::::::.::::::::..:. :::::.::. :::::.:: : :..:::
NP_060 ASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE3 ECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGG
::... .:::::::::.:: :.:.:.::.::.:::::.:.::: :.::::::::::.::
NP_060 ECSLG-ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGE
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE3 FTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCS
: :.::::..:::::.. .:: :.::..::.:.::.:.::: :: :::: .:: :.:.:.
NP_060 FQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECA
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE3 STPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNP
:::: :::::.: :: : : :. :.::. :: .::.:::::::.:.:.::. ..::.: :
NP_060 STPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRP
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE3 GYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG
:: : : .:.:: :.:: . : : : :.: : : ::.: :::::.:::::.:: :
NP_060 GYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE3 ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSC
:.: :. : :.: ::.::. :::.:::::.:::..:.:: .:.::: : :::: : :.:
NP_060 TCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE3 YSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVN
:.:::: ::::.:: : .:.:::: :: :: : ::....::: :::: ::::: ....
NP_060 LSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTS
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE3 GYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCSDDISGYTCHCVLPYTGKNCQTVLAPC
:: :::..::.: :::.::.::::::::::::: ::..:: :.:.::::: .:..:::::
NP_060 GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPC
780 790 800 810 820 830
840 850 860 870 880 890
pF1KE3 SPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMC
.:.::.:.. :..: ..::..:.: ::::: : .::.::. .:: . . :.::.:.: :
NP_060 APSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRC
840 850 860 870 880 890
900 910 920 930 940 950
pF1KE3 ECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP
.: :.:: .:: ::::: :::.::::: ::.:: : ::::: : :. :.::: :.:
NP_060 HCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDP
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KE3 CKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF
:.::..:.: :.:::: : :::.:.::::: .:::::::::::::::::::.:::: ::
NP_060 CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KE3 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGT
:::.: :..:::.:.:::. ::: :: :.:::.:: :::: :::.::. :. ::::: :
NP_060 TGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGK
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KE3 CVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQC
: : ... .: :::::.: :::::.:::..::.:.:: : .::::.:.:..:::::.:.:
NP_060 CWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRC
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KE3 PLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ
::::::::. .:::. .:::.::::.:..::: :.:: ::.:::: :.::: ..:::
NP_060 QAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQ
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KE3 NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDC-------ARGPHCLNGGQCMDRIGGYSC
:::::.:: : .::::: ::.:. :: :.::: .:.:.:.:.: :.:..:::::
NP_060 NGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSC
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KE3 RCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQ
: :::.:::::::.::::::::...:. .:.: .::. : ::.. :::.::. .. :
NP_060 TCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKG
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360
pF1KE3 MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQS---SCGQVKCRKGEQCVHTASGPRCF
:: :::::::::: ::::.:: :: :: :.. .::...: .: :. .: :.
NP_060 KPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCL
1320 1330 1340 1350 1360 1370
1370 1380 1390 1400 1410
pF1KE3 CPSPR---DCE----SGC-ASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL--YT--
: .: .:. : : ...:: . :.:.: . :.: : : :.: :.. :.
NP_060 CLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFG
1380 1390 1400 1410 1420 1430
1420 1430 1440 1450 1460
pF1KE3 ------APPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSP
:: .: : . : . ::. ::.::: ::::::::....:: ::..
NP_060 GGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQS
1440 1450 1460 1470 1480 1490
1470 1480 1490 1500 1510 1520
pF1KE3 LPCWDYINN-QCDELCNTVECLFDNFECQGNSKTCK--YDKYCADHFKDNHCDQGCNSEE
: :: :... .:: ::.. ::::.:.:: :. ::.:: :::.:.:::::::: :
NP_060 LQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAE
1500 1510 1520 1530 1540 1550
1530 1540 1550 1560 1570 1580
pF1KE3 CGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLRIKRDSQGE
: ::::::: :: :: ::::.::::::::: ... ::: :. .::::. .:::..:.
NP_060 CEWDGLDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQ
1560 1570 1580 1590 1600 1610
1590 1600 1610
pF1KE3 LMVYPYYGEKSAAMKKQRMTRRS-----------------LPGEQE----------QEVA
:..:::: . ..:. . : . ::: .: ..:
NP_060 QMIFPYYG-REEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVR
1620 1630 1640 1650 1660 1670
1620 1630 1640 1650 1660 1670
pF1KE3 GSKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYP--LVSVVSESLTPERTQ
:: :.:::::::::: :..::... .::.:.. : :.:. : . .: ::.. :
NP_060 GSIVYLEIDNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPA
1680 1690 1700 1710 1720 1730
1680 1690 1700 1710 1720 1730
pF1KE3 LLYLL--AVAVVIILFIILLGVIMA-KRKRKHGSLWLPEGFTLRRDASNHKRREPVGQDA
:... :.:. ..::.. ::... ::.:.::.::.:::: . .::..:::::.:.:.
NP_060 QLHFMYVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVS-EASKKKRREPLGEDS
1740 1750 1760 1770 1780 1790
1740 1750 1760 1770 1780 1790
pF1KE3 VGLKNLSVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHL
:::: :. ..:.. :. . .: : :: . :: . :. ..: . :: :.: ::::::
NP_060 VGLKPLK-NASDGALMDDNQNE-W-GDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHL
1800 1810 1820 1830 1840
1800 1810 1820 1830 1840 1850
pF1KE3 EAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSDLSDEDEDAEDS
.:::.: . ..: ::::.: ..: .::::::::: ::::.:: ::. . .. .:. ::.
NP_060 DAADLRMS-AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEE-EDA
1850 1860 1870 1880 1890 1900
1860 1870 1880 1890 1900 1910
pF1KE3 SANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPL
: .:.:..::::::. ::::::: ::::::::::.:::::::.:.:::: :::::: ::
NP_060 PA-VISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPL
1910 1920 1930 1940 1950 1960
1920 1930 1940 1950 1960 1970
pF1KE3 HAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVD
::::.::::::::::::::.:::::::.:::::::::::::::::. .::: .:::::::
NP_060 HAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVD
1970 1980 1990 2000 2010 2020
1980 1990 2000 2010 2020 2030
pF1KE3 DHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFA
: ::::::::::::::.:...:::::::.:::.:.:::::::::::::::.::.::::::
NP_060 DLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFA
2030 2040 2050 2060 2070 2080
2040 2050 2060 2070 2080 2090
pF1KE3 NRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPP--GTVL--TSALSPVICGPNRS
::::::::::::::.:..::::::::::::::.. :: :. : : .::: .:.::
NP_060 NRDITDHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGY
2090 2100 2110 2120 2130 2140
2100 2110 2120 2130 2140 2150
pF1KE3 FLSLKHTPMGKKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSP
. ::: .::: :.::.:. : .::::: : .::::: . : : .:: :::
NP_060 LGSLKPGVQGKKVRKPSSKG-----LACGSKEAKDLK-ARRKKSQDGKGCLLDSSGMLSP
2150 2160 2170 2180 2190
2160 2170 2180 2190 2200
pF1KE3 VDSLESPHTYVSDTTSSPMITSPGILQASPN-PMLATAAPPAPVHAQHALSFSNLHEMQP
:::::::: :.::..: :.. :: .: ::. :. . : . :. . ::
NP_060 VDSLESPHGYLSDVASPPLLPSP--FQQSPSVPLNHLPGMPDTHLGIGHLNVAAKPEMAA
2200 2210 2220 2230 2240 2250
2210 2220 2230 2240 2250 2260
pF1KE3 LAHGASTVLPSVSQLLSHHHIVSP-----GSGSAGSLSRL----HPVPVPADWMNRMEVN
:. :. .. . ::: ..: ::.:.:.:. . .:..:.. .
NP_060 LGGGGRLAFETGPPRLSHLPVASGTSTVLGSSSGGALNFTVGGSTSLNGQCEWLSRLQSG
2260 2270 2280 2290 2300 2310
2270 2280 2290
pF1KE3 --ETQYNEMFGMVL-------APA--EGT----HPGIA-------------PQSRPPEGK
.::: . : : ::. .: : ..: :..:
NP_060 MVPNQYNPLRGSVAPGPLSTQAPSLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQP
2320 2330 2340 2350 2360 2370
2300 2310 2320 2330
pF1KE3 HITTPREPLPPIVTFQ---LIP-----KGSIAQPAGAPQPQSTCPPAVAGPL--------
:.. .. : . .: : : . :. : :::. :..: :
NP_060 HLVQTQQVQPQNLQMQQQNLQPANIQQQQSLQPPPPPPQPHLGVSSAASGHLGRSFLSGE
2380 2390 2400 2410 2420 2430
2340 2350 2360 2370 2380 2390
pF1KE3 PTMYQIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSN
:.. .. .. :: ...::.. . : ::. :...... ::::::::.:
NP_060 PSQADVQPLG--PSSLAVHTILPQESPALP-TSLPSSLVPPVTAAQFLTPPSQHSYSSP-
2440 2450 2460 2470 2480 2490
2400 2410 2420 2430 2440 2450
pF1KE3 AAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPTPGGAGGGQRGPG
.. :::
NP_060 -VDNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNVSDWSEGVSSPPTSMQSQIARIPE
2500 2510 2520 2530 2540 2550
>>XP_011517019 (OMIM: 109730,190198,616028) PREDICTED: n (2314 aa)
initn: 7029 init1: 4381 opt: 6009 Z-score: 2355.9 bits: 449.9 E(85289): 1.7e-124
Smith-Waterman score: 9104; 54.6% identity (75.5% similar) in 2272 aa overlap (252-2403:8-2258)
230 240 250 260 270 280
pF1KE3 YVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNT
: :..::.::::::.. :.:::.:::::::
XP_011 MARRPACFTGQNCEENIDDCPGNNCKNGGACVDGVNT
10 20 30
290 300 310 320 330 340
pF1KE3 YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD
:::::::.::::.:::::::: :.:::::::::: : .:::.:::::::.:.::::::::
XP_011 YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDD
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE3 CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYIC
:: :.: :.:: :::::: : ::.:..::::::.::::::::..:. :::::.::. ::
XP_011 CASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAIC
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE3 TCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECH
:::.:: : :..:::::... .:::::::::.:: :.:.:.::.::.:::::.:.:::
XP_011 TCPSGYTGPACSQDVDECSLG-ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECV
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE3 SDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCP
:.::::::::::.:: : :.::::..:::::.. .:: :.::..::.:.::.:.::: ::
XP_011 SNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECP
220 230 240 250 260 270
530 540 550 560 570 580
pF1KE3 PGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHH
:::: .:: :.:.:.:::: :::::.: :: : : :. :.::. :: .::.:::::::.
XP_011 TGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHY
280 290 300 310 320 330
590 600 610 620 630 640
pF1KE3 GQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVN
:.:.::. ..::.: ::: : : .:.:: :.:: . : : : :.: : : ::.: :
XP_011 GSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPN
340 350 360 370 380 390
650 660 670 680 690 700
pF1KE3 CEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGV
::::.:::::.:: : :.: :. : :.: ::.::. :::.:::::.:::..:.:: .:.
XP_011 CEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGI
400 410 420 430 440 450
710 720 730 740 750 760
pF1KE3 NGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNEC
::: : :::: : :.: :.:::: ::::.:: : .:.:::: :: :: : ::....:::
XP_011 NGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNEC
460 470 480 490 500 510
770 780 790 800 810 820
pF1KE3 LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCSDDISGYTCHC
:::: ::::: ....:: :::..::.: :::.::.::::::::::::: ::..:: :.:
XP_011 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNC
520 530 540 550 560 570
830 840 850 860 870 880
pF1KE3 VLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP
.::::: .:..:::::.:.::.:.. :..: ..::..:.: ::::: : .::.::. .:
XP_011 LLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSP
580 590 600 610 620 630
890 900 910 920 930 940
pF1KE3 CMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGF
: . . :.::.:.: :.: :.:: .:: ::::: :::.::::: ::.:: : :::::
XP_011 CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGF
640 650 660 670 680 690
950 960 970 980 990 1000
pF1KE3 TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGT
: :. :.::: :.::.::..:.: :.:::: : :::.:.::::: .:::::::::::
XP_011 RGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGT
700 710 720 730 740 750
1010 1020 1030 1040 1050 1060
pF1KE3 CVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQ
::::::::.:::: :::::.: :..:::.:.:::. ::: :: :.:::.:: :::: :::
XP_011 CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQ
760 770 780 790 800 810
1070 1080 1090 1100 1110 1120
pF1KE3 TLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQ
.::. :. ::::: : : : ... .: :::::.: :::::.:::..::.:.:: : .:::
XP_011 NLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ
820 830 840 850 860 870
1130 1140 1150 1160 1170 1180
pF1KE3 HSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQG
:.:.:..:::::.:.: ::::::::. .:::. .:::.::::.:..::: :.:: ::.:
XP_011 HGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHG
880 890 900 910 920 930
1190 1200 1210 1220 1230
pF1KE3 VNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDC-------ARGPH
::: :.::: ..::::::::.:: : .::::: ::.:. :: :.::: .:.:.
XP_011 VNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPK
940 950 960 970 980 990
1240 1250 1260 1270 1280 1290
pF1KE3 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRS
:.:.: :.:..::::: : :::.:::::::.::::::::...:. .:.: .::. : ::.
XP_011 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA
1000 1010 1020 1030 1040 1050
1300 1310 1320 1330 1340 1350
pF1KE3 AFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQS---SCGQVKC
. :::.::. .. : :: :::::::::: ::::.:: :: :: :.. .::...:
XP_011 GHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRC
1060 1070 1080 1090 1100 1110
1360 1370 1380 1390 1400
pF1KE3 RKGEQCVHTASGPRCFCPSPR---DCE----SGC-ASSPCQHGGSCHPQRQPPYYSCQCA
.: :. .: :.: .: .:. : : ...:: . :.:.: . :.: : :
XP_011 LNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCP
1120 1130 1140 1150 1160 1170
1410 1420 1430 1440 1450
pF1KE3 PPFSGSRCEL--YT--------APPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGG
:.: :.. :. :: .: : . : . ::. ::.::: ::::
XP_011 AKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGG
1180 1190 1200 1210 1220 1230
1460 1470 1480 1490 1500 1510
pF1KE3 DCSLTMENPWANCSSPLPCWDYINN-QCDELCNTVECLFDNFECQGNSKTCK--YDKYCA
::::....:: ::.. : :: :... .:: ::.. ::::.:.:: :. ::.::
XP_011 DCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCK
1240 1250 1260 1270 1280 1290
1520 1530 1540 1550 1560 1570
pF1KE3 DHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRALG
:::.:.:::::::: :: ::::::: :: :: ::::.::::::::: ... ::: :.
XP_011 DHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELS
1300 1310 1320 1330 1340 1350
1580 1590 1600 1610
pF1KE3 TLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRS-----------------LPGE
.::::. .:::..:. :..:::: . ..:. . : . :::
XP_011 RVLHTNVVFKRDAHGQQMIFPYYG-REEELRKHPIKRAAEGWAAPDALLGQVKASLLPGG
1360 1370 1380 1390 1400 1410
1620 1630 1640 1650 1660
pF1KE3 QE----------QEVAGSKVFLEIDNRQCVQDSDHCFKNTDAAAALLASHAIQGTLSYP-
.: ..: :: :.:::::::::: :..::... .::.:.. : :.:. :
XP_011 SEGGRRRRELDPMDVRGSIVYLEIDNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPY
1420 1430 1440 1450 1460 1470
1670 1680 1690 1700 1710
pF1KE3 -LVSVVSESLTPERTQLLYLL--AVAVVIILFIILLGVIMA-KRKRKHGSLWLPEGFTLR
. .: ::.. : :... :.:. ..::.. ::... ::.:.::.::.:::: .
XP_011 KIEAVQSETVEPPPPAQLHFMYVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVS
1480 1490 1500 1510 1520 1530
1720 1730 1740 1750 1760 1770
pF1KE3 RDASNHKRREPVGQDAVGLKNLSVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLS
.::..:::::.:.:.:::: :. ..:.. :. . .: : :: . :: . :. ..:
XP_011 -EASKKKRREPLGEDSVGLKPLK-NASDGALMDDNQNE-W-GDEDLETKKFRFEEPVVLP
1540 1550 1560 1570 1580 1590
1780 1790 1800 1810 1820 1830
pF1KE3 EEDDPIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLR
. :: :.: ::::::.:::.: . ..: ::::.: ..: .::::::::: ::::.::
XP_011 DLDDQTDHRQWTQQHLDAADLRMS-AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCS
1600 1610 1620 1630 1640 1650
1840 1850 1860 1870 1880 1890
pF1KE3 GGSSDLSDEDEDAEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLD
::. . .. .:. ::. : .:.:..::::::. ::::::: ::::::::::.:::::::.
XP_011 GGGLETGNSEEE-EDAPA-VISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLE
1660 1670 1680 1690 1700
1900 1910 1920 1930 1940 1950
pF1KE3 AGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEG
:.:::: :::::: ::::::.::::::::::::::.:::::::.::::::::::::::::
XP_011 ASADANIQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEG
1710 1720 1730 1740 1750 1760
1960 1970 1980 1990 2000 2010
pF1KE3 MVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAA
:. .::: .:::::::: ::::::::::::::.:...:::::::.:::.:.:::::::::
XP_011 MLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAA
1770 1780 1790 1800 1810 1820
2020 2030 2040 2050 2060 2070
pF1KE3 REGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPP--GTVL
::::::.::.::::::::::::::::::::.:..::::::::::::::.. :: :. :
XP_011 REGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGAPL
1830 1840 1850 1860 1870 1880
2080 2090 2100 2110 2120 2130
pF1KE3 --TSALSPVICGPNRSFLSLKHTPMGKKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKS
: .::: .:.:: . ::: .::: :.::.:. : .::::: : .:::::
XP_011 GGTPTLSPPLCSPNGYLGSLKPGVQGKKVRKPSSKG-----LACGSKEAKDLK-ARRKKS
1890 1900 1910 1920 1930 1940
2140 2150 2160 2170 2180 2190
pF1KE3 LSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPMITSPGILQASPNPMLA--TAAPPAP
. : : .:: ::::::::::: :.::..: :.. :: .: ::. : . : .
XP_011 QDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLPSP--FQQSPSVPLNHLPGMPDTH
1950 1960 1970 1980 1990 2000
2200 2210 2220 2230 2240
pF1KE3 VHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHHIVSP-----GSGSAGSLSRL---
. : :. . :: :. :. .. . ::: ..: ::.:.:.:.
XP_011 LGIGH-LNVAAKPEMAALGGGGRLAFETGPPRLSHLPVASGTSTVLGSSSGGALNFTVGG
2010 2020 2030 2040 2050
2250 2260 2270 2280
pF1KE3 -HPVPVPADWMNRMEVN--ETQYNEMFGMVL-------APA--EGT----HPGIA-----
. .:..:.. . .::: . : : ::. .: : ..:
XP_011 STSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAPSLQHGMVGPLHSSLAASALS
2060 2070 2080 2090 2100 2110
2290 2300 2310 2320
pF1KE3 --------PQSRPPEGKHITTPREPLPPIVTFQ---LIP-----KGSIAQPAGAPQPQST
:..: :.. .. : . .: : : . :. : :::.
XP_011 QMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPANIQQQQSLQPPPPPPQPHLG
2120 2130 2140 2150 2160 2170
2330 2340 2350 2360 2370 2380
pF1KE3 CPPAVAGPLPTMYQI--PEMARL----PSVAFPTAMMPQQDGQVAQTILPAYHPFPASVG
:..: : . : .: . :: ...::.. . : ::. :....
XP_011 VSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQESPALP-TSLPSSLVPPVTAA
2180 2190 2200 2210 2220 2230
2390 2400 2410 2420 2430 2440
pF1KE3 KYPTPPSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTT
.. ::::::::.: .. :::
XP_011 QFLTPPSQHSYSS--PVDNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNVSDWSEGVS
2240 2250 2260 2270 2280 2290
>>NP_000426 (OMIM: 125310,130720,600276,615293) neurogen (2321 aa)
initn: 5367 init1: 2004 opt: 5232 Z-score: 2054.2 bits: 394.1 E(85289): 1.1e-107
Smith-Waterman score: 8769; 50.6% identity (70.7% similar) in 2436 aa overlap (67-2450:42-2278)
40 50 60 70 80 90
pF1KE3 NEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPC-EKNRCQNGGTCVAQAMLGKATCRCASG
:: . . : ::: :. : .:.: : :
NP_000 RRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCT-QLPSREAACLCPPG
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE3 FTGEDCQYSTSHPCFVSRPCLNGGTCH---MLSRDTYECTCQVGFTGKECQWTDACLSHP
..:: :: :: : :: . :.:. . . . : : :: : .:. : ::: :
NP_000 WVGERCQLED--PCH-SGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSP
80 90 100 110 120
160 170 180 190 200 210
pF1KE3 CANGSTCTTVAN-QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQ
::.:. :.. . .: :.: :. :..:..::.:: . :.::::::: :::..::::
NP_000 CAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPA
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE3 GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN
:.:: :.. :::::::: :::::::.::.:..: :::::::..:: :.::::.::: :
NP_000 GYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLN
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE3 GGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWS
::.::::::::::.:::.::::::::::::: ::::::.::::: : ::..:::::::.
NP_000 GGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT
250 260 270 280 290 300
340 350 360 370 380 390
pF1KE3 GDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCD
:..::.:::::: : : :.:: :::::: : :: ::.::::::::::.:::::. :.::
NP_000 GESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICD
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE3 TNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGP
:::.::. ::::: :. :. : .:::::... .::::: :.::::.:.: :.: .::.::
NP_000 TNPVNGRAICTCPPGFTGGACDQDVDECSIG-ANPCEHLGRCVNTQGSFLCQCGRGYTGP
370 380 390 400 410 420
460 470 480 490 500 510
pF1KE3 RCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVD
::: :.::: : ::.:.:::::.:: :::.:: :: :..::..:.::::.::::.: : :
NP_000 RCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKD
430 440 450 460 470 480
520 530 540 550 560 570
pF1KE3 KVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI
.:: :.: :: ::.: .::.:.:.:.:::: :::::.:.:.::::.:: :: :.::..:.
NP_000 RVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNV
490 500 510 520 530 540
580 590 600 610 620 630
pF1KE3 DNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQC
:.:.:::::::.: ::: :..: : ::: :. : .:.::: :.:: . :.:.:::. : :
NP_000 DDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLC
550 560 570 580 590 600
640 650 660 670 680 690
pF1KE3 NCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPC
: ::.:::::.:.:::::::: :.: ::::::.:::.::::: ::..:.::::.::
NP_000 RCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPC
610 620 630 640 650 660
700 710 720 730 740 750
pF1KE3 RKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVG
.:..:..: :::::.:: : : : . : .:: :: : . .:..:.:. :: :
NP_000 GEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSG
670 680 690 700 710 720
760 770 780 790 800
pF1KE3 INCE--VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGT
: . .. : :.::. ::::.. :..::: : .: .:..
NP_000 PRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL---------------
730 740 750 760 770
810 820 830 840 850 860
pF1KE3 CSDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQR
:.::.:::::... :. .:. . .: : :::: :
NP_000 ------------------------LSPCTPNPCEHGGRCESAPG-QLPVCSCPQGWQGPR
780 790 800
870 880 890 900 910 920
pF1KE3 CTIDIDECISK-PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMD
: :.::: . :: ::.: : ::. : : :..: .:..::.:: ::: :::::.:
NP_000 CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQD
810 820 830 840 850 860
930 940 950 960 970 980
pF1KE3 GVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI
::..::: :::::.: .: :..::::.:: . :::.:.: :.:: : :. : :::...
NP_000 GVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDL
870 880 890 900 910 920
990 1000 1010 1020 1030 1040
pF1KE3 NECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYR
.:. ::::::::::::.::::::: :.::. : :: . : :.:::. :.: . .:
NP_000 PDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFR
930 940 950 960 970 980
1050 1060 1070 1080 1090 1100
pF1KE3 CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIA
:.: ..:: .:::::. :::.::.: : ::: : :::: ::.: ::. .. : :
NP_000 CTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA--YCLCPPGWSGRLCDIRSLPCREA
990 1000 1010 1020 1030 1040
1110 1120 1130 1140 1150 1160
pF1KE3 ASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFI
:.. :: .:.::: .: :.. ..::: :: : :::.::...: : ..:::::.:: ..
NP_000 AAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYM
1050 1060 1070 1080 1090 1100
1170 1180 1190 1200 1210 1220
pF1KE3 GGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDD
::: :::.:::.: ::: .:::: .::::.::.::::: .. ::::::: :.::: : ::
NP_000 GGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDD
1110 1120 1130 1140 1150 1160
1230 1240 1250 1260 1270 1280
pF1KE3 CA------RGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCI
:. ::.::..: :.: .::. : : ::..: :::.::::: :. : . . ::.
NP_000 CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCL
1170 1180 1190 1200 1210 1220
1290 1300 1310 1320 1330
pF1KE3 QLTND-YLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDG---FICRCPPGFS
: . . :.:...:.: .:.: .. : ..:: .:: : : : : : :.: :
NP_000 QDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCR-PSPGPGGGLTFTCHCAQPFW
1230 1240 1250 1260 1270 1280
1340 1350 1360 1370 1380
pF1KE3 GARCQS---SCGQVKCRKGEQCVHTASGPRCFCP---SPRDCES-----------GCASS
: ::. :: ...: : : .: :::: :: : .:.: .::..
NP_000 GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAA
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430
pF1KE3 PCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPP--STPPATCLSQYCADKARDGVC
:: :::::.: :.. : :: ..: ::: .: : : : : : : : :
NP_000 PCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEP-RCPRAACQAKRGDQRC
1350 1360 1370 1380 1390 1400
1440 1450 1460 1470 1480 1490
pF1KE3 DEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINN-QCDELCNTVECLFDNFECQ-
:. ::: .: ::::::::.. .:: .: . : :: .:: .:: :.. ::.:::.:.
NP_000 DRECNSPGCGWDGGDCSLSVGDPWRQCEA-LQCWRLFNNSRCDPACSSPACLYDNFDCHA
1410 1420 1430 1440 1450 1460
1500 1510 1520 1530 1540 1550
pF1KE3 -GNSKTCK--YDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMP
: .::. :.::::::: :..::::::.:::::::::::.. : ::.:.::..::.:
NP_000 GGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVPALLARGVLVLTVLLP
1470 1480 1490 1500 1510 1520
1560 1570 1580 1590 1600 1610
pF1KE3 PEQLLQDARSFLRALGTLLHTNLRIKRDSQGELMVYPYYGEKSAAMKKQRMTRRSLPGEQ
::.::... .::. :...:.:.::.. :..:. ::.::. . . .. : :. :
NP_000 PEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYH--RPSPGSEPRARRELAP---
1530 1540 1550 1560 1570
1620 1630 1640 1650 1660 1670
pF1KE3 EQEVAGSKVFLEIDNRQCVQ--DSDHCFKNTDAAAALL-ASHAIQGT-LSYPLVSVVSES
:: :: :.:::::: :.: ..:::: ....:: : : :.. . ::: .: .:
NP_000 --EVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEP
1580 1590 1600 1610 1620 1630
1680 1690 1700 1710 1720
pF1KE3 LTPERTQ--LLYLLAVAVVIILFIILLGVIMAKRKRKHGSLWLPEGFTLRRD-ASNHK-R
: : . . :: ::....:..: :..:::..:.:::.:..::.::::.:..: ::.:: :
NP_000 LEPPEPSVPLLPLLVAGAVLLLVILVLGVMVARRKREHSTLWFPEGFSLHKDVASGHKGR
1640 1650 1660 1670 1680 1690
1730 1740 1750 1760 1770 1780
pF1KE3 REPVGQDAVGLKNLSVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEALLSEEDDPIDR
::::::::.:.::.. : :.: ... :.: : :. :..:.:. .. .:: .:
NP_000 REPVGQDALGMKNMAKGES---LMGEVATD-WMDTECPEAKRLKVEEPGMGAEE--AVDC
1700 1710 1720 1730 1740
1790 1800 1810 1820 1830 1840
pF1KE3 RPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLASLRGGSSD-LS
: :::.:: ::::: .:..::::::.. ..: .::::::::: :::::::. ::. . .
NP_000 RQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCGGALEPMP
1750 1760 1770 1780 1790 1800
1850 1860 1870 1880 1890 1900
pF1KE3 DEDEDAEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANA
:...:.:.::.::.::. :::.: :.:::::: ::::::::.::::::::::::::.::
NP_000 TEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNA
1810 1820 1830 1840 1850 1860
1910 1920 1930 1940 1950 1960
pF1KE3 QDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELIN
::. :: :::.::.:::::::::::::: ::::::: ::.: ::::::::::::: :::
NP_000 QDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIA
1870 1880 1890 1900 1910 1920
1970 1980 1990 2000 2010 2020
pF1KE3 CQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEA
.:::::::. :::::::::::::::::: :::::::.::::.:::::::::::::::::
NP_000 SHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEA
1930 1940 1950 1960 1970 1980
2030 2040 2050 2060 2070 2080
pF1KE3 AKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPGTVLTSALSPVIC
::.::::::::.::::.::::::::..:.:.:::::::. . :::: .:.:..:
NP_000 AKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPPGP---HGLGPLLC
1990 2000 2010 2020 2030 2040
2090 2100 2110 2120 2130 2140
pF1KE3 GPNRSFLSLKHTPMG-KKSRRPSAKSTMPTSLPNLAKEAKDAKGSRRKKSLSEKVQLSES
:. . .:: . : :::::: .:. . . : .: .: .:. :..:
NP_000 PPGAFLPGLKAAQSGSKKSRRPPGKAGLGPQGP---------RGRGKKLTLACPGPLADS
2050 2060 2070 2080 2090
2150 2160 2170 2180 2190 2200
pF1KE3 SVTLSPVDSLESPHTYVSDTTSSPMITSPGILQASPNPMLATAAPPAPVHAQHALSFSNL
::::::::::.::. . ..: .::: . :. .: : . : :.:...:
NP_000 SVTLSPVDSLDSPRPF-----GGPP-ASPGGF-----PL---EGPYAAATAT-AVSLAQL
2100 2110 2120 2130 2140
2210 2220 2230 2240 2250 2260
pF1KE3 HEMQPLAHGASTVLPSVSQLLSHHHIVSPGSGSAGSLSRLHPVPVPADWMNRMEVNETQY
:. :. . : . : .: . ::. :.:: :: :: :.
NP_000 --------GG----PGRAGLGRQ-----PPGGCVLSLGLLNPVAVPLDWA-RL-------
2150 2160 2170
2270 2280 2290 2300 2310 2320
pF1KE3 NEMFGMVLAPAEGTHPGIAPQSRPPEGKHITTPREPLPPIVTFQLIPKGSIAQPAGAPQP
:: : :: .: :.: :: :
NP_000 -----------------------PP----------PAPPGPSF-LLPL--------APGP
2180 2190
2330 2340 2350 2360 2370 2380
pF1KE3 QSTCPPAVAGPLPTMYQIPEMARLPSVAFPTAMMPQQDGQVAQTILPAYHPFPASVGKYP
: : . :. . . : : .: : :. .::. : .
NP_000 QLLNP---GTPVSPQERPP-----PYLAVPG------HGE----------EYPAA-GAHS
2200 2210 2220
2390 2400 2410 2420 2430 2440
pF1KE3 TPPSQHSYASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSSPHSASDWSDVTTSPT
.::. . :.:: ::::::::::::..:.: :: : ::::. ..:.
NP_000 SPPKARFL-------RVPS-------EHPYLTPSPESPEHWASPSPPSLSDWSE--STPS
2230 2240 2250 2260 2270
2450 2460 2470
pF1KE3 PGGAGGGQRGPGTHMSEPPHNNMQVYA
:. : :
NP_000 PATATGAMATTTGALPAQPLPLSVPSSLAQAQTQLGPQPEVTPKRQVLA
2280 2290 2300 2310 2320
2471 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:30:19 2016 done: Tue Nov 8 03:30:22 2016
Total Scan time: 18.800 Total Display time: 1.660
Function used was FASTA [36.3.4 Apr, 2011]