Result of FASTA (omim) for pF1KE3023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3023, 138 aa
  1>>>pF1KE3023     138 - 138 aa - 138 aa
Library: /omim/omim.rfq.tfa
  65951994 residues in 93482 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0008+/-0.000331; mu= 13.1890+/- 0.020
 mean_var=67.1228+/-13.769, 0's: 0 Z-trim(115.5): 33  B-trim: 199 in 1/49
 Lambda= 0.156545
 statistics sampled from 27183 (27210) to 27183 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.291), width:  16
 Scan time:  2.630

The best scores are:                                      opt bits E(93482)
NP_000540 (OMIM: 188540,275100) thyrotropin subuni ( 138)  977 228.9 2.2e-60
XP_011540367 (OMIM: 188540,275100) thyrotropin sub ( 138)  977 228.9 2.2e-60
NP_001264920 (OMIM: 188540,275100) thyrotropin sub (  93)  603 144.3 4.2e-35
NP_000501 (OMIM: 136530,229070) follitropin subuni ( 129)  378 93.6 1.1e-19
NP_001018090 (OMIM: 136530,229070) follitropin sub ( 129)  378 93.6 1.1e-19
NP_000885 (OMIM: 152780,228300) lutropin subunit b ( 141)  355 88.5 4.2e-18
XP_011525277 (OMIM: 152780,228300) lutropin subuni ( 157)  355 88.5 4.6e-18
NP_203695 (OMIM: 608823) choriogonadotropin subuni ( 155)  337 84.4 7.7e-17
NP_203696 (OMIM: 608824) choriogonadotropin subuni ( 163)  337 84.4   8e-17
NP_000728 (OMIM: 118860) choriogonadotropin subuni ( 165)  337 84.5   8e-17
NP_149439 (OMIM: 608827) chorionic gonadotropin, b ( 165)  337 84.5   8e-17
NP_149032 (OMIM: 608825) chorionic gonadotropin, b ( 165)  337 84.5   8e-17
XP_005258536 (OMIM: 608824) choriogonadotropin sub ( 181)  337 84.5 8.6e-17
NP_149133 (OMIM: 608826) choriogonadotropin subuni ( 165)  336 84.2 9.4e-17
XP_024307552 (OMIM: 608826) choriogonadotropin sub ( 165)  336 84.2 9.4e-17
NP_001305994 (OMIM: 608824) choriogonadotropin sub ( 151)  333 83.5 1.4e-16
NP_660154 (OMIM: 609652) glycoprotein hormone beta ( 130)  221 58.2 5.1e-09


>>NP_000540 (OMIM: 188540,275100) thyrotropin subunit be  (138 aa)
 initn: 977 init1: 977 opt: 977  Z-score: 1206.0  bits: 228.9 E(93482): 2.2e-60
Smith-Waterman score: 977; 99.3% identity (100.0% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KE3 MTALFLMSMLFGLACGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
       :::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
               70        80        90       100       110       120

              130        
pF1KE3 KTNYCTKPQKSYLVGFSV
       ::::::::::::::::::
NP_000 KTNYCTKPQKSYLVGFSV
              130        

>>XP_011540367 (OMIM: 188540,275100) thyrotropin subunit  (138 aa)
 initn: 977 init1: 977 opt: 977  Z-score: 1206.0  bits: 228.9 E(93482): 2.2e-60
Smith-Waterman score: 977; 99.3% identity (100.0% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KE3 MTALFLMSMLFGLACGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
       :::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
               70        80        90       100       110       120

              130        
pF1KE3 KTNYCTKPQKSYLVGFSV
       ::::::::::::::::::
XP_011 KTNYCTKPQKSYLVGFSV
              130        

>>NP_001264920 (OMIM: 188540,275100) thyrotropin subunit  (93 aa)
 initn: 603 init1: 603 opt: 603  Z-score: 751.9  bits: 144.3 E(93482): 4.2e-35
Smith-Waterman score: 603; 98.8% identity (100.0% similar) in 85 aa overlap (54-138:9-93)

            30        40        50        60        70        80   
pF1KE3 PTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVE
                                     .:::::::::::::::::::::::::::::
NP_001                       MLSFLFFPQDINGKLFLPKYALSQDVCTYRDFIYRTVE
                                     10        20        30        

            90       100       110       120       130        
pF1KE3 IPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV
       40        50        60        70        80        90   

>>NP_000501 (OMIM: 136530,229070) follitropin subunit be  (129 aa)
 initn: 402 init1: 224 opt: 378  Z-score: 475.2  bits: 93.6 E(93482): 1.1e-19
Smith-Waterman score: 378; 40.2% identity (72.1% similar) in 122 aa overlap (7-126:4-123)

               10          20        30        40        50        
pF1KE3 MTALFLMSMLFGLACGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDING
             ....: . : .:.  . :  :. :. ::..:: .:..:::: :::::.:::.  
NP_000    MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVY
                  10        20        30        40        50       

       60        70        80        90       100       110        
pF1KE3 KLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHE
       :   :     : .::.....:.::..:::  :.   ..:::: .:.::::..: .::  .
NP_000 KD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVR
          60        70        80        90       100       110     

      120       130        
pF1KE3 AIKTNYCTKPQKSYLVGFSV
       ..  .::.            
NP_000 GLGPSYCSFGEMKE      
         120               

>>NP_001018090 (OMIM: 136530,229070) follitropin subunit  (129 aa)
 initn: 402 init1: 224 opt: 378  Z-score: 475.2  bits: 93.6 E(93482): 1.1e-19
Smith-Waterman score: 378; 40.2% identity (72.1% similar) in 122 aa overlap (7-126:4-123)

               10          20        30        40        50        
pF1KE3 MTALFLMSMLFGLACGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDING
             ....: . : .:.  . :  :. :. ::..:: .:..:::: :::::.:::.  
NP_001    MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVY
                  10        20        30        40        50       

       60        70        80        90       100       110        
pF1KE3 KLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHE
       :   :     : .::.....:.::..:::  :.   ..:::: .:.::::..: .::  .
NP_001 KD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVR
          60        70        80        90       100       110     

      120       130        
pF1KE3 AIKTNYCTKPQKSYLVGFSV
       ..  .::.            
NP_001 GLGPSYCSFGEMKE      
         120               

>>NP_000885 (OMIM: 152780,228300) lutropin subunit beta   (141 aa)
 initn: 369 init1: 225 opt: 355  Z-score: 446.6  bits: 88.5 E(93482): 4.2e-18
Smith-Waterman score: 355; 41.7% identity (61.4% similar) in 132 aa overlap (4-134:10-139)

                     10        20         30        40        50   
pF1KE3       MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYCMT
                :.:.::  . :  . .  .: : .  . .:.. :  :.:.::::::::: :
NP_000 MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPT
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS
            .  ::   : : ::::::  ......::::  : :  :.::::::.:: :  . :
NP_000 MMRVLQAVLP--PLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTS
               70          80        90       100       110        

           120       130        
pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV
       ::     .   : .:: : :.    
NP_000 DCGGPKDHPLTCDHPQLSGLLFL  
      120       130       140   

>>XP_011525277 (OMIM: 152780,228300) lutropin subunit be  (157 aa)
 initn: 356 init1: 225 opt: 355  Z-score: 446.0  bits: 88.5 E(93482): 4.6e-18
Smith-Waterman score: 355; 41.7% identity (61.4% similar) in 132 aa overlap (4-134:26-155)

                                     10        20         30       
pF1KE3                       MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECA
                                :.:.::  . :  . .  .: : .  . .:.. : 
XP_011 MGRPGLGAAVSDLGEAVSLSQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCP
               10        20        30        40        50        60

        40        50        60        70        80        90       
pF1KE3 YCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSY
        :.:.::::::::: :     .  ::   : : ::::::  ......::::  : :  :.
XP_011 VCITVNTTICAGYCPTMMRVLQAVLP--PLPQVVCTYRDVRFESIRLPGCPRGVDPVVSF
               70        80          90       100       110        

       100       110       120       130        
pF1KE3 PVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV
       ::::::.:: :  . :::     .   : .:: : :.    
XP_011 PVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL  
      120       130       140       150         

>>NP_203695 (OMIM: 608823) choriogonadotropin subunit be  (155 aa)
 initn: 321 init1: 197 opt: 337  Z-score: 424.1  bits: 84.4 E(93482): 7.7e-17
Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:8-132)

                   10        20         30        40        50     
pF1KE3     MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC--MT
              :.:.::    :  . .   : : . :. .:.. :  :.:.:::::::::  ::
NP_203 MSKRLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMT
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS
       : ..:   ::  :: : ::.:::  ......::::  : :  :: :::::.:. :  . .
NP_203 RVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTT
                   70        80        90       100       110      

           120       130                      
pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV              
       ::     .   :  :.                       
NP_203 DCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGP
        120       130       140       150     

>>NP_203696 (OMIM: 608824) choriogonadotropin subunit be  (163 aa)
 initn: 321 init1: 197 opt: 337  Z-score: 423.8  bits: 84.4 E(93482): 8e-17
Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:8-132)

                   10        20         30        40        50     
pF1KE3     MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC--MT
              :.:.::    :  . .   : : . :. .:.. :  :.:.:::::::::  ::
NP_203 MSKGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMT
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS
       : ..:   ::  :: : ::.:::  ......::::  : :  :: :::::.:. :  . .
NP_203 RVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTT
                   70        80        90       100       110      

           120       130                              
pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV                      
       ::     .   :  :.                               
NP_203 DCGGPKDHPLTCDDPRFQASSSSKAPPPSLPSPSRLPGPSDTPILPQ
        120       130       140       150       160   

>>NP_000728 (OMIM: 118860) choriogonadotropin subunit be  (165 aa)
 initn: 321 init1: 197 opt: 337  Z-score: 423.7  bits: 84.5 E(93482): 8e-17
Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:10-134)

                     10        20         30        40        50   
pF1KE3       MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC--
                :.:.::    :  . .   : : . :. .:.. :  :.:.:::::::::  
NP_000 MEMFQGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPT
               10        20        30        40        50        60

              60        70        80        90       100       110 
pF1KE3 MTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTD
       ::: ..:   ::  :: : ::.:::  ......::::  : :  :: :::::.:. :  .
NP_000 MTRVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRS
                 70          80        90       100       110      

             120       130                              
pF1KE3 YSDCIHEAIKTNYCTKPQKSYLVGFSV                      
        .::     .   :  :.                               
NP_000 TTDCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ
        120       130       140       150       160     




138 residues in 1 query   sequences
65951994 residues in 93482 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Jun 20 10:38:24 2019 done: Thu Jun 20 10:38:24 2019
 Total Scan time:  2.630 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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