Result of FASTA (omim) for
pF1KE3328
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3328, 936 aa
1>>>pF1KE3328 936 - 936 aa - 936 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.6561+/-0.00104; mu= -23.1529+/- 0.063
mean_var=1210.8333+/-264.288, 0's: 0 Z-trim(113.7): 1164 B-trim: 0 in 0/51
Lambda= 0.036858
statistics sampled from 21916 (23124) to 21916 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.271), width: 16
Scan time: 10.890
The best scores are: opt bits E(85289)
NP_057062 (OMIM: 613932,616117) serine/threonine-p ( 835) 5507 311.1 1.5e-83
NP_001186258 (OMIM: 603609) fucose-1-phosphate gua ( 182) 750 57.2 9.1e-08
NP_001186257 (OMIM: 603609) fucose-1-phosphate gua ( 353) 754 57.8 1.1e-07
NP_003829 (OMIM: 603609) fucose-1-phosphate guanyl ( 607) 754 58.2 1.5e-07
NP_002437 (OMIM: 600137) mitogen-activated protein ( 954) 545 47.3 0.00042
NP_663306 (OMIM: 157800,602614,617137) mitogen-act ( 491) 530 46.1 0.00052
NP_663305 (OMIM: 157800,602614,617137) mitogen-act ( 518) 530 46.1 0.00053
NP_003179 (OMIM: 157800,602614,617137) mitogen-act ( 579) 530 46.2 0.00056
NP_663304 (OMIM: 157800,602614,617137) mitogen-act ( 606) 530 46.2 0.00058
XP_011525284 (OMIM: 600137) PREDICTED: mitogen-act ( 860) 520 46.0 0.001
NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform (1719) 530 46.9 0.001
XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751) 530 47.0 0.001
XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752) 530 47.0 0.001
XP_016868818 (OMIM: 182900,612641) PREDICTED: anky (1759) 530 47.0 0.001
XP_011542805 (OMIM: 182900,612641) PREDICTED: anky (1791) 530 47.0 0.001
XP_016868817 (OMIM: 182900,612641) PREDICTED: anky (1792) 530 47.0 0.001
XP_016868816 (OMIM: 182900,612641) PREDICTED: anky (1807) 530 47.0 0.001
NP_065208 (OMIM: 182900,612641) ankyrin-1 isoform (1856) 530 47.0 0.0011
NP_000028 (OMIM: 182900,612641) ankyrin-1 isoform (1880) 530 47.0 0.0011
NP_065209 (OMIM: 182900,612641) ankyrin-1 isoform (1881) 530 47.0 0.0011
XP_011542804 (OMIM: 182900,612641) PREDICTED: anky (1889) 530 47.0 0.0011
XP_016868815 (OMIM: 182900,612641) PREDICTED: anky (1892) 530 47.0 0.0011
NP_001135918 (OMIM: 182900,612641) ankyrin-1 isofo (1897) 530 47.0 0.0011
XP_011525283 (OMIM: 600137) PREDICTED: mitogen-act ( 962) 520 46.0 0.0011
XP_016868814 (OMIM: 182900,612641) PREDICTED: anky (1908) 530 47.0 0.0011
XP_011542803 (OMIM: 182900,612641) PREDICTED: anky (1913) 530 47.0 0.0011
XP_011542802 (OMIM: 182900,612641) PREDICTED: anky (1914) 530 47.0 0.0011
XP_005273533 (OMIM: 182900,612641) PREDICTED: anky (1921) 530 47.0 0.0011
XP_016868813 (OMIM: 182900,612641) PREDICTED: anky (1922) 530 47.0 0.0011
XP_016868812 (OMIM: 182900,612641) PREDICTED: anky (1936) 530 47.0 0.0011
XP_016868811 (OMIM: 182900,612641) PREDICTED: anky (1937) 530 47.0 0.0011
XP_016868810 (OMIM: 182900,612641) PREDICTED: anky (1940) 530 47.0 0.0011
XP_011542798 (OMIM: 182900,612641) PREDICTED: anky (1944) 530 47.0 0.0011
XP_016868809 (OMIM: 182900,612641) PREDICTED: anky (1946) 530 47.0 0.0011
XP_011542797 (OMIM: 182900,612641) PREDICTED: anky (1953) 530 47.0 0.0011
XP_011542796 (OMIM: 182900,612641) PREDICTED: anky (1954) 530 47.0 0.0011
XP_016868808 (OMIM: 182900,612641) PREDICTED: anky (1961) 530 47.0 0.0011
XP_011542793 (OMIM: 182900,612641) PREDICTED: anky (1968) 530 47.0 0.0011
XP_011542792 (OMIM: 182900,612641) PREDICTED: anky (1969) 530 47.0 0.0011
NP_002410 (OMIM: 600050) mitogen-activated protein ( 847) 492 44.5 0.0028
XP_016871638 (OMIM: 600465,615493) PREDICTED: anky (1720) 491 44.9 0.0043
XP_016871637 (OMIM: 600465,615493) PREDICTED: anky (1725) 491 44.9 0.0043
XP_016871636 (OMIM: 600465,615493) PREDICTED: anky (1735) 491 44.9 0.0043
XP_016871635 (OMIM: 600465,615493) PREDICTED: anky (1737) 491 44.9 0.0043
XP_016871634 (OMIM: 600465,615493) PREDICTED: anky (1738) 491 44.9 0.0043
XP_016871633 (OMIM: 600465,615493) PREDICTED: anky (1741) 491 44.9 0.0043
XP_016871632 (OMIM: 600465,615493) PREDICTED: anky (1742) 491 44.9 0.0043
XP_016871631 (OMIM: 600465,615493) PREDICTED: anky (1747) 491 44.9 0.0043
XP_016871630 (OMIM: 600465,615493) PREDICTED: anky (1751) 491 44.9 0.0043
XP_016871629 (OMIM: 600465,615493) PREDICTED: anky (1763) 491 44.9 0.0043
>>NP_057062 (OMIM: 613932,616117) serine/threonine-prote (835 aa)
initn: 5507 init1: 5507 opt: 5507 Z-score: 1621.1 bits: 311.1 E(85289): 1.5e-83
Smith-Waterman score: 5507; 99.9% identity (100.0% similar) in 823 aa overlap (114-936:13-835)
90 100 110 120 130 140
pF1KE3 GNGGSTLCALQCLEKLYGDKWNSFTILLIHSDEWKKKVSESYVITIERLEDDLQIKEKEL
.:::::::::::::::::::::::::::::
NP_057 MGNYKSRPTQTCTDEWKKKVSESYVITIERLEDDLQIKEKEL
10 20 30 40
150 160 170 180 190 200
pF1KE3 TELRNIFGSDEAFSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TELRNIFGSDEAFSKVNLNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGF
50 60 70 80 90 100
210 220 230 240 250 260
pF1KE3 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE3 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE
170 180 190 200 210 220
330 340 350 360 370 380
pF1KE3 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGK
230 240 250 260 270 280
390 400 410 420 430 440
pF1KE3 FEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHT
290 300 310 320 330 340
450 460 470 480 490 500
pF1KE3 GLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLK
350 360 370 380 390 400
510 520 530 540 550 560
pF1KE3 HYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 HYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSE
410 420 430 440 450 460
570 580 590 600 610 620
pF1KE3 IEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVI
470 480 490 500 510 520
630 640 650 660 670 680
pF1KE3 QFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQ
530 540 550 560 570 580
690 700 710 720 730 740
pF1KE3 PIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRY
590 600 610 620 630 640
750 760 770 780 790 800
pF1KE3 TIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGW
650 660 670 680 690 700
810 820 830 840 850 860
pF1KE3 NACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAA
710 720 730 740 750 760
870 880 890 900 910 920
pF1KE3 LRSRFELEYALNARSYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LRSRFELEYALNARSYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHF
770 780 790 800 810 820
930
pF1KE3 HSCRNSSSFEDSS
:::::::::::::
NP_057 HSCRNSSSFEDSS
830
>>NP_001186258 (OMIM: 603609) fucose-1-phosphate guanyly (182 aa)
initn: 750 init1: 750 opt: 750 Z-score: 260.4 bits: 57.2 E(85289): 9.1e-08
Smith-Waterman score: 750; 100.0% identity (100.0% similar) in 114 aa overlap (1-114:14-127)
10 20 30 40
pF1KE3 MAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAVRRGLREGGAMAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 TILLIHSDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVNLNYRTEN
:::::::
NP_001 TILLIHSVSFQIYQNALAKHPVSFKAYWIQDVLWHLAQLWSIPDWGLMFQLGKTALLVVL
130 140 150 160 170 180
>>NP_001186257 (OMIM: 603609) fucose-1-phosphate guanyly (353 aa)
initn: 754 init1: 754 opt: 754 Z-score: 258.8 bits: 57.8 E(85289): 1.1e-07
Smith-Waterman score: 754; 94.2% identity (98.3% similar) in 121 aa overlap (1-121:14-134)
10 20 30 40
pF1KE3 MAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAVRRGLREGGAMAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 TILLIHSDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVNLNYRTEN
::::::: .....
NP_001 TILLIHSGGYSQRLPNASALGKIFTALPLDIPECSGKTSCIIQSILDSRCSVAPGSVVEY
130 140 150 160 170 180
>>NP_003829 (OMIM: 603609) fucose-1-phosphate guanylyltr (607 aa)
initn: 754 init1: 754 opt: 754 Z-score: 256.5 bits: 58.2 E(85289): 1.5e-07
Smith-Waterman score: 754; 94.2% identity (98.3% similar) in 121 aa overlap (1-121:14-134)
10 20 30 40
pF1KE3 MAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE
:::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRAVRRGLREGGAMAAARDPPEVSLREATQRKLRRFSELRGKLVARGEFWDIVAITAADE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KQELAYNQQLSEKLKRKELPLGVQYHVFVDPAGAKIGNGGSTLCALQCLEKLYGDKWNSF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 TILLIHSDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVNLNYRTEN
::::::: .....
NP_003 TILLIHSGGYSQRLPNASALGKIFTALPLGNPIYQMLELKLAMYIDFPLNMNPGILVTCA
130 140 150 160 170 180
>>NP_002437 (OMIM: 600137) mitogen-activated protein kin (954 aa)
initn: 539 init1: 211 opt: 545 Z-score: 194.6 bits: 47.3 E(85289): 0.00042
Smith-Waterman score: 545; 35.7% identity (67.1% similar) in 283 aa overlap (551-821:85-358)
530 540 550 560 570 580
pF1KE3 GGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYK
::: .. . :....:::: :.:::::.
NP_002 DEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYR
60 70 80 90 100 110
590 600 610 620 630
pF1KE3 GRCRNKIVAIKRYRANTYCSKS-DVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIV
. :.. ::.: : . . . ... :.:. .. :.:: .: . ::::: : .. .:
NP_002 ALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLN-PPHLCLV
120 130 140 150 160 170
640 650 660 670 680 690
pF1KE3 TQYISGGSLFSLLHEQKRILDLQSKLII--AVDVAKGMEYLHNLTQ-PIIHRDLNSHNIL
.: ::.: .: .:. .... ::.::.::.:::: . :::::::.: :::
NP_002 MEYARGGALSRVL-AGRRV---PPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINIL
180 190 200 210 220
700 710 720 730 740
pF1KE3 LYE--DGHAV------VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKAD
. : ..: . ..::: .: .. . :. :. ::::::. . . .. ..:
NP_002 ILEAIENHNLADTVLKITDFGLAREWHKTTK--MSAA-GTYAWMAPEVI-RLSLFSKSSD
230 240 250 260 270 280
750 760 770 780 790 800
pF1KE3 VFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPE
:.:... :::.::::.:. .. :.: .:.... :: . :.:.. :: . :. :.
NP_002 VWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPH
290 300 310 320 330 340
810 820 830 840 850 860
pF1KE3 GRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRF
:::.:. .. .::
NP_002 GRPDFGSILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEEL
350 360 370 380 390 400
>>NP_663306 (OMIM: 157800,602614,617137) mitogen-activat (491 aa)
initn: 361 init1: 134 opt: 530 Z-score: 193.0 bits: 46.1 E(85289): 0.00052
Smith-Waterman score: 530; 33.8% identity (60.3% similar) in 305 aa overlap (559-852:31-321)
530 540 550 560 570 580
pF1KE3 VPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIV
.. .::: .:..: :.:: : :.. : : :
NP_663 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
10 20 30 40 50 60
590 600 610 620 630 640
pF1KE3 AIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSL
:::. . :.:. : :. : ..::: .... ::::: : .: .: ::::
NP_663 AIKQIE-----SESERKAFIVELRQLSRVNHPNIVKLYGACLN-P--VCLVMEYAEGGSL
70 80 90 100 110
650 660 670 680 690 700
pF1KE3 FSLLH--EQKRILDLQSKLIIAVDVAKGMEYLHNLTQP--IIHRDLNSHNILLYEDGHAV
...:: : . .. ..:. :::.. :: .:::::. :.:: : ..
NP_663 YNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSM-QPKALIHRDLKPPNLLLVAGGTVL
120 130 140 150 160 170
710 720 730 740 750 760
pF1KE3 -VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGE
. ::: . .:. .::.. :. ::::::: . . :. : ::::... :::..: .
NP_663 KICDFGTACDIQT----HMTNNKGSAAWMAPEVF-EGSNYSEKCDVFSWGIILWEVITRR
180 190 200 210 220
770 780 790 800 810 820
pF1KE3 IPFAHLKPAAAAADMAYHH-IRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEE
:: .. : : :. :::. ..:::: ::. : :. : :: . :.: . .
NP_663 KPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTH
230 240 250 260 270 280
830 840 850 860 870
pF1KE3 CL-----CNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR
. . :. : . .. :. . ..:. ...
NP_663 LMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIK
290 300 310 320 330 340
880 890 900 910 920 930
pF1KE3 SYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHFHSCRNSSSFEDSS
NP_663 RLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTGNG
350 360 370 380 390 400
>>NP_663305 (OMIM: 157800,602614,617137) mitogen-activat (518 aa)
initn: 361 init1: 134 opt: 530 Z-score: 192.8 bits: 46.1 E(85289): 0.00053
Smith-Waterman score: 530; 33.8% identity (60.3% similar) in 305 aa overlap (559-852:31-321)
530 540 550 560 570 580
pF1KE3 VPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIV
.. .::: .:..: :.:: : :.. : : :
NP_663 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
10 20 30 40 50 60
590 600 610 620 630 640
pF1KE3 AIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSL
:::. . :.:. : :. : ..::: .... ::::: : .: .: ::::
NP_663 AIKQIE-----SESERKAFIVELRQLSRVNHPNIVKLYGACLN-P--VCLVMEYAEGGSL
70 80 90 100 110
650 660 670 680 690 700
pF1KE3 FSLLH--EQKRILDLQSKLIIAVDVAKGMEYLHNLTQP--IIHRDLNSHNILLYEDGHAV
...:: : . .. ..:. :::.. :: .:::::. :.:: : ..
NP_663 YNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSM-QPKALIHRDLKPPNLLLVAGGTVL
120 130 140 150 160 170
710 720 730 740 750 760
pF1KE3 -VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGE
. ::: . .:. .::.. :. ::::::: . . :. : ::::... :::..: .
NP_663 KICDFGTACDIQT----HMTNNKGSAAWMAPEVF-EGSNYSEKCDVFSWGIILWEVITRR
180 190 200 210 220
770 780 790 800 810 820
pF1KE3 IPFAHLKPAAAAADMAYHH-IRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEE
:: .. : : :. :::. ..:::: ::. : :. : :: . :.: . .
NP_663 KPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTH
230 240 250 260 270 280
830 840 850 860 870
pF1KE3 CL-----CNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR
. . :. : . .. :. . ..:. ...
NP_663 LMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIK
290 300 310 320 330 340
880 890 900 910 920 930
pF1KE3 SYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHFHSCRNSSSFEDSS
NP_663 RLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTAYS
350 360 370 380 390 400
>>NP_003179 (OMIM: 157800,602614,617137) mitogen-activat (579 aa)
initn: 361 init1: 134 opt: 530 Z-score: 192.3 bits: 46.2 E(85289): 0.00056
Smith-Waterman score: 530; 33.8% identity (60.3% similar) in 305 aa overlap (559-852:31-321)
530 540 550 560 570 580
pF1KE3 VPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIV
.. .::: .:..: :.:: : :.. : : :
NP_003 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
10 20 30 40 50 60
590 600 610 620 630 640
pF1KE3 AIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSL
:::. . :.:. : :. : ..::: .... ::::: : .: .: ::::
NP_003 AIKQIE-----SESERKAFIVELRQLSRVNHPNIVKLYGACLN-P--VCLVMEYAEGGSL
70 80 90 100 110
650 660 670 680 690 700
pF1KE3 FSLLH--EQKRILDLQSKLIIAVDVAKGMEYLHNLTQP--IIHRDLNSHNILLYEDGHAV
...:: : . .. ..:. :::.. :: .:::::. :.:: : ..
NP_003 YNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSM-QPKALIHRDLKPPNLLLVAGGTVL
120 130 140 150 160 170
710 720 730 740 750 760
pF1KE3 -VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGE
. ::: . .:. .::.. :. ::::::: . . :. : ::::... :::..: .
NP_003 KICDFGTACDIQT----HMTNNKGSAAWMAPEVF-EGSNYSEKCDVFSWGIILWEVITRR
180 190 200 210 220
770 780 790 800 810 820
pF1KE3 IPFAHLKPAAAAADMAYHH-IRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEE
:: .. : : :. :::. ..:::: ::. : :. : :: . :.: . .
NP_003 KPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTH
230 240 250 260 270 280
830 840 850 860 870
pF1KE3 CL-----CNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR
. . :. : . .. :. . ..:. ...
NP_003 LMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIK
290 300 310 320 330 340
880 890 900 910 920 930
pF1KE3 SYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHFHSCRNSSSFEDSS
NP_003 RLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTGNG
350 360 370 380 390 400
>>NP_663304 (OMIM: 157800,602614,617137) mitogen-activat (606 aa)
initn: 361 init1: 134 opt: 530 Z-score: 192.2 bits: 46.2 E(85289): 0.00058
Smith-Waterman score: 530; 33.8% identity (60.3% similar) in 305 aa overlap (559-852:31-321)
530 540 550 560 570 580
pF1KE3 VPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIV
.. .::: .:..: :.:: : :.. : : :
NP_663 MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDV
10 20 30 40 50 60
590 600 610 620 630 640
pF1KE3 AIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSL
:::. . :.:. : :. : ..::: .... ::::: : .: .: ::::
NP_663 AIKQIE-----SESERKAFIVELRQLSRVNHPNIVKLYGACLN-P--VCLVMEYAEGGSL
70 80 90 100 110
650 660 670 680 690 700
pF1KE3 FSLLH--EQKRILDLQSKLIIAVDVAKGMEYLHNLTQP--IIHRDLNSHNILLYEDGHAV
...:: : . .. ..:. :::.. :: .:::::. :.:: : ..
NP_663 YNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSM-QPKALIHRDLKPPNLLLVAGGTVL
120 130 140 150 160 170
710 720 730 740 750 760
pF1KE3 -VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGE
. ::: . .:. .::.. :. ::::::: . . :. : ::::... :::..: .
NP_663 KICDFGTACDIQT----HMTNNKGSAAWMAPEVF-EGSNYSEKCDVFSWGIILWEVITRR
180 190 200 210 220
770 780 790 800 810 820
pF1KE3 IPFAHLKPAAAAADMAYHH-IRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEE
:: .. : : :. :::. ..:::: ::. : :. : :: . :.: . .
NP_663 KPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTH
230 240 250 260 270 280
830 840 850 860 870
pF1KE3 CL-----CNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR
. . :. : . .. :. . ..:. ...
NP_663 LMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIK
290 300 310 320 330 340
880 890 900 910 920 930
pF1KE3 SYAALSQSAGQYSSQGLSLEEMKRSLQYTPIDKYGYVSDPMSSMHFHSCRNSSSFEDSS
NP_663 RLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTAYS
350 360 370 380 390 400
>>XP_011525284 (OMIM: 600137) PREDICTED: mitogen-activat (860 aa)
initn: 473 init1: 145 opt: 520 Z-score: 187.8 bits: 46.0 E(85289): 0.001
Smith-Waterman score: 520; 34.9% identity (65.4% similar) in 292 aa overlap (551-821:85-366)
530 540 550 560 570 580
pF1KE3 GGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYK
::: .. . :....:::: :.:::::.
XP_011 DEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYR
60 70 80 90 100 110
590 600 610 620 630
pF1KE3 GRCRNKIVAIKRYRANTYCSKS-DVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIV
. :.. ::.: : . . . ... :.:. .. :.:: .: . ::::: : .. .:
XP_011 ALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLN-PPHLCLV
120 130 140 150 160 170
640 650 660 670 680 690
pF1KE3 TQYISGGSLFSLLHEQKRILDLQSKLII--AVDVAKGMEYLHNLTQ-PIIHRDLNSHNIL
.: ::.: .: .:. .... ::.::.::.:::: . :::::::.: :::
XP_011 MEYARGGALSRVL-AGRRV---PPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINIL
180 190 200 210 220
700 710 720 730 740
pF1KE3 LYE--DGHAV------VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKAD
. : ..: . ..::: .: .. . :. :. ::::::. . . .. ..:
XP_011 ILEAIENHNLADTVLKITDFGLAREWHKTTK--MSAA-GTYAWMAPEVI-RLSLFSKSSD
230 240 250 260 270 280
750 760 770 780 790 800
pF1KE3 VFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRG------
:.:... :::.::::.:. .. :.: .:.... :: . :.:.. :: .:
XP_011 VWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLL-EGEPGPRD
290 300 310 320 330 340
810 820 830 840 850
pF1KE3 ---WNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRS
:. :.:::.:. .. .::
XP_011 EECWDPDPHGRPDFGSILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEK
350 360 370 380 390 400
936 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:16:17 2016 done: Sun Nov 6 19:16:19 2016
Total Scan time: 10.890 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]