Result of FASTA (omim) for pF1KE3815
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3815, 485 aa
  1>>>pF1KE3815     485 - 485 aa - 485 aa
Library: /omim/omim.rfq.tfa
  64704883 residues in 91410 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.3942+/-0.000424; mu= -5.9047+/- 0.026
 mean_var=559.4730+/-113.338, 0's: 0 Z-trim(125.4): 44  B-trim: 862 in 1/60
 Lambda= 0.054223
 statistics sampled from 50730 (50802) to 50730 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.824), E-opt: 0.2 (0.556), width:  16
 Scan time:  5.570

The best scores are:                                      opt bits E(91410)
NP_001292997 (OMIM: 606009) double homeobox protei ( 424) 3014 250.2 9.2e-66
NP_001280727 (OMIM: 606009) double homeobox protei ( 424) 3014 250.2 9.2e-66
XP_024308351 (OMIM: 606009) double homeobox protei ( 424) 3001 249.2 1.9e-65
XP_024308352 (OMIM: 606009) double homeobox protei ( 424) 3001 249.2 1.9e-65
NP_001350749 (OMIM: 606009) double homeobox protei ( 160) 1103 100.1 5.1e-21
NP_036281 (OMIM: 611444) double homeobox protein 5 ( 197) 1080 98.5   2e-20
NP_036278 (OMIM: 611441) double homeobox protein 1 ( 170)  926 86.3 7.7e-17


>>NP_001292997 (OMIM: 606009) double homeobox protein 4   (424 aa)
 initn: 3014 init1: 3014 opt: 3014  Z-score: 1302.2  bits: 250.2 E(91410): 9.2e-66
Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 424 aa overlap (62-485:1-424)

              40        50        60        70        80        90 
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                             10        20        30

             100       110       120       130       140       150 
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
              160       170       180       190       200       210

             280       290       300       310       320       330 
pF1KE3 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
              220       230       240       250       260       270

             340       350       360       370       380       390 
pF1KE3 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
              280       290       300       310       320       330

             400       410       420       430       440       450 
pF1KE3 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
              340       350       360       370       380       390

             460       470       480     
pF1KE3 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
       ::::::::::::::::::::::::::::::::::
NP_001 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
              400       410       420    

>>NP_001280727 (OMIM: 606009) double homeobox protein 4   (424 aa)
 initn: 3014 init1: 3014 opt: 3014  Z-score: 1302.2  bits: 250.2 E(91410): 9.2e-66
Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 424 aa overlap (62-485:1-424)

              40        50        60        70        80        90 
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                             10        20        30

             100       110       120       130       140       150 
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
              160       170       180       190       200       210

             280       290       300       310       320       330 
pF1KE3 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
              220       230       240       250       260       270

             340       350       360       370       380       390 
pF1KE3 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
              280       290       300       310       320       330

             400       410       420       430       440       450 
pF1KE3 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
              340       350       360       370       380       390

             460       470       480     
pF1KE3 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
       ::::::::::::::::::::::::::::::::::
NP_001 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
              400       410       420    

>>XP_024308351 (OMIM: 606009) double homeobox protein 4-  (424 aa)
 initn: 3001 init1: 3001 opt: 3001  Z-score: 1296.7  bits: 249.2 E(91410): 1.9e-65
Smith-Waterman score: 3001; 99.5% identity (99.5% similar) in 424 aa overlap (62-485:1-424)

              40        50        60        70        80        90 
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                     ::::::::::::::::::::::::::::::
XP_024                               MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                             10        20        30

             100       110       120       130       140       150 
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
              160       170       180       190       200       210

             280       290       300       310       320       330 
pF1KE3 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
              220       230       240       250       260       270

             340       350       360       370       380       390 
pF1KE3 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
              280       290       300       310       320       330

             400       410       420       430       440       450 
pF1KE3 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
       :::::::::::::::::::::::::::::: :::::: ::::::::::::::::::::::
XP_024 PPPQPAPPDASASARQGQMQGIPAPSQALQXPAPWSAXPCGLLLDELLASPEFLQQAQPL
              340       350       360       370       380       390

             460       470       480     
pF1KE3 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
       ::::::::::::::::::::::::::::::::::
XP_024 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
              400       410       420    

>>XP_024308352 (OMIM: 606009) double homeobox protein 4-  (424 aa)
 initn: 3001 init1: 3001 opt: 3001  Z-score: 1296.7  bits: 249.2 E(91410): 1.9e-65
Smith-Waterman score: 3001; 99.5% identity (99.5% similar) in 424 aa overlap (62-485:1-424)

              40        50        60        70        80        90 
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                     ::::::::::::::::::::::::::::::
XP_024                               MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                             10        20        30

             100       110       120       130       140       150 
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
              160       170       180       190       200       210

             280       290       300       310       320       330 
pF1KE3 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
              220       230       240       250       260       270

             340       350       360       370       380       390 
pF1KE3 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
              280       290       300       310       320       330

             400       410       420       430       440       450 
pF1KE3 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
       :::::::::::::::::::::::::::::: :::::: ::::::::::::::::::::::
XP_024 PPPQPAPPDASASARQGQMQGIPAPSQALQXPAPWSAXPCGLLLDELLASPEFLQQAQPL
              340       350       360       370       380       390

             460       470       480     
pF1KE3 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
       ::::::::::::::::::::::::::::::::::
XP_024 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
              400       410       420    

>>NP_001350749 (OMIM: 606009) double homeobox protein 4   (160 aa)
 initn: 1128 init1: 1103 opt: 1103  Z-score: 499.0  bits: 100.1 E(91410): 5.1e-21
Smith-Waterman score: 1103; 100.0% identity (100.0% similar) in 159 aa overlap (62-220:1-159)

              40        50        60        70        80        90 
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                             10        20        30

             100       110       120       130       140       150 
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
       :::::::::                                                   
NP_001 GQGGRAPAQV                                                  
              160                                                  

>>NP_036281 (OMIM: 611444) double homeobox protein 5 [Ho  (197 aa)
 initn: 1341 init1: 1080 opt: 1080  Z-score: 488.2  bits: 98.5 E(91410): 2e-20
Smith-Waterman score: 1080; 82.1% identity (89.3% similar) in 196 aa overlap (36-231:2-197)

          10        20        30        40        50        60     
pF1KE3 LPACGPLQGRLAGWLAVRAGLLAAPAAVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALP
                                     ::::::::::::::  ::::::::  ::: 
NP_036                              MPAEVHGSPPASLCPCQSVKFRPGLPEMALL
                                            10        20        30 

          70        80        90       100       110       120     
pF1KE3 TPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQ
       :  :.::: ::.: :::  :. :::::.::::::::: ::::::.:.:::.: :::::::
NP_036 TALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPEPRVQ
              40        50        60        70        80        90 

         130       140       150       160       170       180     
pF1KE3 IWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAR
       :::::::: :::::::.:::::::: : .:::::::.:::::::::::::::::::::::
NP_036 IWFQNERSCQLRQHRRQSRPWPGRRDPQKGRRKRTAITGSQTALLLRAFEKDRFPGIAAR
             100       110       120       130       140       150 

         190       200       210       220       230       240     
pF1KE3 EELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTG
       ::::::::::::::::::::::::: ::.::::.::.  :.::: :              
NP_036 EELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG              
             160       170       180       190                     

         250       260       270       280       290       300     
pF1KE3 AWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGISQPAPARGDFAYAAP

>>NP_036278 (OMIM: 611441) double homeobox protein 1 [Ho  (170 aa)
 initn: 1152 init1: 926 opt: 926  Z-score: 423.8  bits: 86.3 E(91410): 7.7e-17
Smith-Waterman score: 926; 81.8% identity (90.0% similar) in 170 aa overlap (62-231:1-170)

              40        50        60        70        80        90 
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
                                     ::: :  :.::: ::.: :::  :. ::::
NP_036                               MALLTALDDTLPEEAQGPGRRMILLSTPSQ
                                             10        20        30

             100       110       120       130       140       150 
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
       :.::::::::: ::::::.:.:::.: ::::::::::::::: :::::::.:::::::: 
NP_036 SDALRACFERNLYPGIATKEELAQGIDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRD
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
       : .:::::::.:::::::::::::::::::::::::::::::::::::::::::::::: 
NP_036 PQKGRRKRTAITGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHR
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
       ::.::::.::.  :.::: :                                        
NP_036 GQSGRAPTQASIRCNAAPIG                                        
              160       170                                        




485 residues in 1 query   sequences
64704883 residues in 91410 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Jul 24 16:39:25 2018 done: Tue Jul 24 16:39:26 2018
 Total Scan time:  5.570 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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