Result of FASTA (omim) for pF1KE3355
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3355, 1047 aa
  1>>>pF1KE3355     1047 - 1047 aa - 1047 aa
Library: /omim/omim.rfq.tfa
  64848753 residues in 91609 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9673+/-0.000623; mu= 3.4614+/- 0.037
 mean_var=512.7882+/-125.399, 0's: 0 Z-trim(112.6): 420  B-trim: 1013 in 1/52
 Lambda= 0.056638
 statistics sampled from 21967 (22391) to 21967 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.59), E-opt: 0.2 (0.244), width:  16
 Scan time:  6.810

The best scores are:                                      opt bits E(91609)
NP_003986 (OMIM: 108961,602875,615923,616255) atri (1047) 7020 591.2 1.1e-167
XP_005251535 (OMIM: 108961,602875,615923,616255) a (1050) 7004 589.9 2.7e-167
XP_024303325 (OMIM: 108961,602875,615923,616255) a (1100) 4608 394.1 2.4e-108
XP_024303324 (OMIM: 108961,602875,615923,616255) a (1103) 4592 392.8  6e-108
NP_000897 (OMIM: 108960) atrial natriuretic peptid (1061) 4181 359.2 7.6e-98
XP_024303329 (OMIM: 108961,602875,615923,616255) a ( 579) 3838 330.7 1.5e-89
XP_005245275 (OMIM: 108960) atrial natriuretic pep (1035) 2520 223.5 5.4e-57
XP_024303328 (OMIM: 108961,602875,615923,616255) a ( 632) 2427 215.5 8.1e-55
XP_024303327 (OMIM: 108961,602875,615923,616255) a ( 635) 2427 215.5 8.1e-55
XP_024303326 (OMIM: 108961,602875,615923,616255) a ( 774) 2427 215.6   9e-55
XP_016856863 (OMIM: 108960) atrial natriuretic pep ( 704) 2269 202.7 6.6e-51
NP_001513 (OMIM: 300041) retinal guanylyl cyclase  (1108) 1712 157.5 4.2e-37
XP_011522118 (OMIM: 204000,215500,600179,601777) r (1103) 1677 154.6   3e-36
NP_000171 (OMIM: 204000,215500,600179,601777) reti (1103) 1677 154.6   3e-36
XP_011518933 (OMIM: 601330,614616,614665) heat-sta ( 991) 1411 132.8   1e-29
NP_004954 (OMIM: 601330,614616,614665) heat-stable (1073) 1411 132.9   1e-29
NP_000846 (OMIM: 601244) guanylate cyclase soluble ( 732)  604 66.7 6.1e-10
XP_005263013 (OMIM: 139396,615750) guanylate cycla ( 455)  582 64.5 1.7e-09
NP_001124157 (OMIM: 139396,615750) guanylate cycla ( 455)  582 64.5 1.7e-09
XP_005263014 (OMIM: 139396,615750) guanylate cycla ( 455)  582 64.5 1.7e-09
XP_011530202 (OMIM: 139396,615750) guanylate cycla ( 455)  582 64.5 1.7e-09
NP_001243378 (OMIM: 139396,615750) guanylate cycla ( 690)  582 64.8   2e-09
XP_006714259 (OMIM: 139396,615750) guanylate cycla ( 690)  582 64.8   2e-09
NP_001124156 (OMIM: 139396,615750) guanylate cycla ( 690)  582 64.8   2e-09
XP_005263012 (OMIM: 139396,615750) guanylate cycla ( 690)  582 64.8   2e-09
XP_006714260 (OMIM: 139396,615750) guanylate cycla ( 690)  582 64.8   2e-09
NP_000847 (OMIM: 139396,615750) guanylate cyclase  ( 690)  582 64.8   2e-09
NP_001124154 (OMIM: 139396,615750) guanylate cycla ( 690)  582 64.8   2e-09
NP_001124155 (OMIM: 139396,615750) guanylate cycla ( 690)  582 64.8   2e-09
NP_001124159 (OMIM: 139396,615750) guanylate cycla ( 624)  577 64.3 2.6e-09
XP_016863622 (OMIM: 139397) guanylate cyclase solu ( 551)  569 63.6 3.8e-09
NP_001278884 (OMIM: 139397) guanylate cyclase solu ( 551)  569 63.6 3.8e-09
XP_016863621 (OMIM: 139397) guanylate cyclase solu ( 551)  569 63.6 3.8e-09
NP_001278881 (OMIM: 139397) guanylate cyclase solu ( 599)  569 63.6   4e-09
NP_000848 (OMIM: 139397) guanylate cyclase soluble ( 619)  569 63.7   4e-09
NP_001278880 (OMIM: 139397) guanylate cyclase solu ( 641)  569 63.7 4.1e-09
NP_001278882 (OMIM: 139397) guanylate cyclase solu ( 594)  539 61.2 2.2e-08
XP_016863620 (OMIM: 139397) guanylate cyclase solu ( 594)  539 61.2 2.2e-08
XP_016863619 (OMIM: 139397) guanylate cyclase solu ( 594)  539 61.2 2.2e-08
XP_011530203 (OMIM: 139397) guanylate cyclase solu ( 662)  539 61.3 2.3e-08
NP_000899 (OMIM: 108962) atrial natriuretic peptid ( 540)  509 58.7 1.1e-07
NP_001191304 (OMIM: 108962) atrial natriuretic pep ( 541)  509 58.7 1.1e-07
NP_001278883 (OMIM: 139397) guanylate cyclase solu ( 586)  436 52.8 7.3e-06
NP_001243353 (OMIM: 601244) guanylate cyclase solu ( 763)  415 51.2 2.8e-05
XP_011512352 (OMIM: 108962) atrial natriuretic pep ( 272)  399 49.2   4e-05
XP_016864981 (OMIM: 108962) atrial natriuretic pep ( 500)  397 49.5 6.2e-05
NP_003812 (OMIM: 603455) receptor-interacting seri ( 540)  364 46.8 0.00042
NP_848605 (OMIM: 608774) ankyrin repeat and protei ( 765)  357 46.5 0.00074
XP_011541039 (OMIM: 608774) ankyrin repeat and pro ( 766)  357 46.5 0.00074
XP_016858682 (OMIM: 600291,617885) adenylate cycla ( 903)  355 46.5  0.0009


>>NP_003986 (OMIM: 108961,602875,615923,616255) atrial n  (1047 aa)
 initn: 7020 init1: 7020 opt: 7020  Z-score: 3132.0  bits: 591.2 E(91609): 1.1e-167
Smith-Waterman score: 7020; 100.0% identity (100.0% similar) in 1047 aa overlap (1-1047:1-1047)

               10        20        30        40        50        60
pF1KE3 MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 PVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 TAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 YFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 QRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRED
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 GLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE3 LMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE3 GHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE3 RGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE3 TDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE3 SGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE3 QIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPH
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE3 SVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE3 DVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE3 HTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELR
              970       980       990      1000      1010      1020

             1030      1040       
pF1KE3 GDVEMKGKGKMRTYWLLGERKGPPGLL
       :::::::::::::::::::::::::::
NP_003 GDVEMKGKGKMRTYWLLGERKGPPGLL
             1030      1040       

>>XP_005251535 (OMIM: 108961,602875,615923,616255) atria  (1050 aa)
 initn: 3778 init1: 3778 opt: 7004  Z-score: 3124.9  bits: 589.9 E(91609): 2.7e-167
Smith-Waterman score: 7004; 99.7% identity (99.7% similar) in 1050 aa overlap (1-1047:1-1050)

               10        20        30        40        50        60
pF1KE3 MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 PVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 TAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 YFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 QRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRED
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 GLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWW
              370       380       390       400       410       420

              430       440       450       460       470          
pF1KE3 TGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFR-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_005 TGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRP
              430       440       450       460       470       480

       480       490       500       510       520       530       
pF1KE3 --KLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIF
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRKLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIF
              490       500       510       520       530       540

       540       550       560       570       580       590       
pF1KE3 ANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTE
              550       560       570       580       590       600

       600       610       620       630       640       650       
pF1KE3 YCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFV
              610       620       630       640       650       660

       660       670       680       690       700       710       
pF1KE3 LKITDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKITDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEI
              670       680       690       700       710       720

       720       730       740       750       760       770       
pF1KE3 ALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERP
              730       740       750       760       770       780

       780       790       800       810       820       830       
pF1KE3 DFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQI
              790       800       810       820       830       840

       840       850       860       870       880       890       
pF1KE3 LPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAII
              850       860       870       880       890       900

       900       910       920       930       940       950       
pF1KE3 DNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLR
              910       920       930       940       950       960

       960       970       980       990      1000      1010       
pF1KE3 IGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQL
              970       980       990      1000      1010      1020

      1020      1030      1040       
pF1KE3 ELRGDVEMKGKGKMRTYWLLGERKGPPGLL
       ::::::::::::::::::::::::::::::
XP_005 ELRGDVEMKGKGKMRTYWLLGERKGPPGLL
             1030      1040      1050

>>XP_024303325 (OMIM: 108961,602875,615923,616255) atria  (1100 aa)
 initn: 4608 init1: 4608 opt: 4608  Z-score: 2066.6  bits: 394.1 E(91609): 2.4e-108
Smith-Waterman score: 6746; 95.0% identity (95.1% similar) in 1079 aa overlap (1-1026:1-1079)

               10        20        30        40        50        60
pF1KE3 MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 PVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 TAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 YFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 YFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 QRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRED
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 GLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE3 LMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE3 GHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE3 RGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKI
              610       620       630       640       650       660

              670       680                                        
pF1KE3 TDYGLASFRSTAEPDDSHALYA--------------------------------------
       ::::::::::::::::::::::                                      
XP_024 TDYGLASFRSTAEPDDSHALYASEAHPHNPLFILLLFPPRDGGRGRWSDSNIGMSPGGLG
              670       680       690       700       710       720

                           690       700       710       720       
pF1KE3 ---------------KKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLE
                      .::::::::::::::::::::::::::::::::::::::::::::
XP_024 GAPFRGTWPAGFLFSEKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLE
              730       740       750       760       770       780

       730       740       750       760       770       780       
pF1KE3 GLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIR
              790       800       810       820       830       840

       790       800       810       820       830       840       
pF1KE3 RFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLK
              850       860       870       880       890       900

       850       860       870       880       890       900       
pF1KE3 RGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVET
              910       920       930       940       950       960

       910       920       930       940       950       960       
pF1KE3 IGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 IGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCA
              970       980       990      1000      1010      1020

       970       980       990      1000      1010      1020       
pF1KE3 GVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_024 GVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKG
             1030      1040      1050      1060      1070      1080

      1030      1040       
pF1KE3 KGKMRTYWLLGERKGPPGLL
                           
XP_024 KGKMRTYWLLGERKGPPGLL
             1090      1100

>>XP_024303324 (OMIM: 108961,602875,615923,616255) atria  (1103 aa)
 initn: 5657 init1: 3253 opt: 4592  Z-score: 2059.5  bits: 392.8 E(91609): 6e-108
Smith-Waterman score: 6711; 94.7% identity (94.8% similar) in 1079 aa overlap (1-1023:1-1079)

               10        20        30        40        50        60
pF1KE3 MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 PVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 TAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 YFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 YFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 QRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYRE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRED
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 GLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWW
              370       380       390       400       410       420

              430       440       450       460       470          
pF1KE3 TGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFR-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_024 TGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRP
              430       440       450       460       470       480

       480       490       500       510       520       530       
pF1KE3 --KLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIF
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 YRKLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIF
              490       500       510       520       530       540

       540       550       560       570       580       590       
pF1KE3 ANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTE
              550       560       570       580       590       600

       600       610       620       630       640       650       
pF1KE3 YCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 YCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFV
              610       620       630       640       650       660

       660       670       680                                     
pF1KE3 LKITDYGLASFRSTAEPDDSHALYA-----------------------------------
       :::::::::::::::::::::::::                                   
XP_024 LKITDYGLASFRSTAEPDDSHALYASEAHPHNPLFILLLFPPRDGGRGRWSDSNIGMSPG
              670       680       690       700       710       720

                              690       700       710       720    
pF1KE3 ------------------KKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPF
                         .:::::::::::::::::::::::::::::::::::::::::
XP_024 GLGGAPFRGTWPAGFLFSEKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPF
              730       740       750       760       770       780

          730       740       750       760       770       780    
pF1KE3 YLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 YLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKG
              790       800       810       820       830       840

          790       800       810       820       830       840    
pF1KE3 FIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAE
              850       860       870       880       890       900

          850       860       870       880       890       900    
pF1KE3 QLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYK
              910       920       930       940       950       960

          910       920       930       940       950       960    
pF1KE3 VETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGP
              970       980       990      1000      1010      1020

          970       980       990      1000      1010      1020    
pF1KE3 VCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_024 VCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVE
             1030      1040      1050      1060      1070      1080

         1030      1040       
pF1KE3 MKGKGKMRTYWLLGERKGPPGLL
                              
XP_024 MKGKGKMRTYWLLGERKGPPGLL
             1090      1100   

>>NP_000897 (OMIM: 108960) atrial natriuretic peptide re  (1061 aa)
 initn: 3605 init1: 1950 opt: 4181  Z-score: 1878.2  bits: 359.2 E(91609): 7.6e-98
Smith-Waterman score: 4181; 62.0% identity (81.6% similar) in 1048 aa overlap (6-1040:16-1055)

                         10        20        30        40        50
pF1KE3           MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVA
                      ::::.  :   .:   : :::.:::::  : :: :.: :::::: 
NP_000 MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVE
               10        20        30        40        50        60

                  60           70         80        90       100   
pF1KE3 LA---VEALGRALP-VDLRFV--SSELE-GACSEYLAPLSAVDLKLYHDPDLLLGPGCVY
       ::   :.:    ::   .: :  :::   :.::.  :::.:::::  :.: ..:::::::
NP_000 LALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVY
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KE3 PAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWT
        :: :.::..:::.::::::: : ::..: :.:   .:.:::  :::.::..:: ...: 
NP_000 AAAPVGRFTAHWRVPLLTAGAPALGFGVK-DEYALTTRAGPSYAKLGDFVAALHRRLGWE
              130       140        150       160       170         

           170       180        190        200       210           
pF1KE3 ARAALLYLDARTDDRPH-YFTIEGVFEALQGS-NLSVQHQVYAREPGGPEQATHFIRA--
        .: .::   :  :. : .: .::.:  ..   :..:.:  .:..  .  . :...:.  
NP_000 RQALMLYA-YRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLS--HYTRLLRTMP
     180        190       200       210       220         230      

      220       230       240       250       260       270        
pF1KE3 -NGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNR
        .::..:::.  . .. ..: : . .: . :::::.::.::.::..:   :  :::.  :
NP_000 RKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWE--R
        240       250       260       270       280       290      

      280       290       300       310       320       330        
pF1KE3 TREQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFY
          :  . :.:::.. .:::..: :::: :: ..:   : :.:.  .  .:.: : . :.
NP_000 GDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFH
          300       310       320       330       340       350    

      340       350       360       370       380       390        
pF1KE3 DGILLYAEVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMG
       ::.::: ....::. .:::  ::  :...: .: ..:::: . .:...:::::: :: : 
NP_000 DGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDM-
          360       370       380       390       400       410    

      400       410        420       430       440       450       
pF1KE3 DLDSGDFQPAAHYSGAEKQ-IWWTGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLA
       : ..: :. . .:.:. .. .  .:: . :  : :: : : :.:: .::.:..  :::: 
NP_000 DPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLE
           420       430       440       450       460       470   

       460       470       480       490       500       510       
pF1KE3 IVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTL
       ..::  ..... . . ::.:.::..::::::: :::.:::... .. ::. ..:::::::
NP_000 VLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTL
           480       490       500       510       520       530   

       520       530       540       550       560       570       
pF1KE3 SLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFN
       : :::.::::.:..:..:.::.:...:::.::.:.::.:::::::.:::::::::::: .
NP_000 SGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNE
           540       550       560       570       580       590   

       580       590       600       610       620       630       
pF1KE3 HLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNS
       :::::.::: :::::::.:::::::::::::::.::.::::::::: ::.:::: ::::.
NP_000 HLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNG
           600       610       620       630       640       650   

       640       650       660       670       680       690       
pF1KE3 IISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPL
        : :::.:::::::::.::::::::::: :::.  .:...:..::::::::::::     
NP_000 AICSHGNLKSSNCVVDGRFVLKITDYGLESFRDL-DPEQGHTVYAKKLWTAPELLRMASP
           660       670       680        690       700       710  

       700       710       720       730       740       750       
pF1KE3 PTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQL
       :. : : .::::::::::::::::: :..::::::::::...:  :..: ::::.   . 
NP_000 PVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSH
            720       730       740       750       760       770  

       760       770       780       790       800       810       
pF1KE3 NEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVE
        ::: :::.::::.:: ::: : ::.  .:.::.:....:::::: ::::::::::.:::
NP_000 LEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVE
            780       790       800       810       820       830  

       820       830       840       850       860       870       
pF1KE3 ERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAES
            840       850       860       870       880       890  

       880       890       900       910       920       930       
pF1KE3 TPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALAL
       ::::::::::::::::::.::::::::::::::::::::::: :::. :: :.:::::::
NP_000 TPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALAL
            900       910       920       930       940       950  

       940       950       960       970       980       990       
pF1KE3 LDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQAL
       :::: ::::::::..:::::::.::::::::::::::::::::::::::::::::::.::
NP_000 LDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEAL
            960       970       980       990      1000      1010  

      1000      1010      1020      1030      1040       
pF1KE3 KIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKGPPGLL
       :::.:: :: .:.:.: :.::::::::::::::.:::::::::       
NP_000 KIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG 
           1020      1030      1040      1050      1060  

>>XP_024303329 (OMIM: 108961,602875,615923,616255) atria  (579 aa)
 initn: 3838 init1: 3838 opt: 3838  Z-score: 1729.1  bits: 330.7 E(91609): 1.5e-89
Smith-Waterman score: 3838; 100.0% identity (100.0% similar) in 579 aa overlap (469-1047:1-579)

      440       450       460       470       480       490        
pF1KE3 CAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEE
                                     ::::::::::::::::::::::::::::::
XP_024                               MFGVSSFLIFRKLMLEKELASMLWRIRWEE
                                             10        20        30

      500       510       520       530       540       550        
pF1KE3 LQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRI
               40        50        60        70        80        90

      560       570       580       590       600       610        
pF1KE3 ELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWM
              100       110       120       130       140       150

      620       630       640       650       660       670        
pF1KE3 FRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSH
              160       170       180       190       200       210

      680       690       700       710       720       730        
pF1KE3 ALYAKKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ALYAKKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQ
              220       230       240       250       260       270

      740       750       760       770       780       790        
pF1KE3 KVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSIL
              280       290       300       310       320       330

      800       810       820       830       840       850        
pF1KE3 DNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFD
              340       350       360       370       380       390

      860       870       880       890       900       910        
pF1KE3 SVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGL
              400       410       420       430       440       450

      920       930       940       950       960       970        
pF1KE3 PGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYC
              460       470       480       490       500       510

      980       990      1000      1010      1020      1030        
pF1KE3 LFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLG
              520       530       540       550       560       570

     1040       
pF1KE3 ERKGPPGLL
       :::::::::
XP_024 ERKGPPGLL
                

>>XP_005245275 (OMIM: 108960) atrial natriuretic peptide  (1035 aa)
 initn: 3096 init1: 1950 opt: 2520  Z-score: 1144.8  bits: 223.5 E(91609): 5.4e-57
Smith-Waterman score: 3980; 60.0% identity (79.1% similar) in 1048 aa overlap (6-1040:16-1029)

                         10        20        30        40        50
pF1KE3           MALPSLLLLVAALAGGVRPPGARNLTLAVVLPEHNLSYAWAWPRVGPAVA
                      ::::.  :   .:   : :::.:::::  : :: :.: :::::: 
XP_005 MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVE
               10        20        30        40        50        60

                  60           70         80        90       100   
pF1KE3 LA---VEALGRALP-VDLRFV--SSELE-GACSEYLAPLSAVDLKLYHDPDLLLGPGCVY
       ::   :.:    ::   .: :  :::   :.::.  :::.:::::  :.: ..:::::::
XP_005 LALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVY
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KE3 PAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWT
        :: :.::..:::.::::::: : ::..: :.:   .:.:::  :::.::..:: ...: 
XP_005 AAAPVGRFTAHWRVPLLTAGAPALGFGVK-DEYALTTRAGPSYAKLGDFVAALHRRLGWE
              130       140        150       160       170         

           170       180        190        200       210           
pF1KE3 ARAALLYLDARTDDRPH-YFTIEGVFEALQGS-NLSVQHQVYAREPGGPEQATHFIRA--
        .: .::   :  :. : .: .::.:  ..   :..:.:  .:..  .  . :...:.  
XP_005 RQALMLYA-YRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLS--HYTRLLRTMP
     180        190       200       210       220         230      

      220       230       240       250       260       270        
pF1KE3 -NGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNR
        .::..:::.  . .. ..: : . .: . :::::.::.::.::..:   :  :::.  :
XP_005 RKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWE--R
        240       250       260       270       280       290      

      280       290       300       310       320       330        
pF1KE3 TREQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFY
          :  . :.:::.. .:::..: :::: :: ..:   : :.:.  .  .:.: : . :.
XP_005 GDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFH
          300       310       320       330       340       350    

      340       350       360       370       380       390        
pF1KE3 DGILLYAEVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMG
       ::.::: ....::. .:::  ::  :...: .: ..:::: . .:...:::::: :: : 
XP_005 DGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDM-
          360       370       380       390       400       410    

      400       410        420       430       440       450       
pF1KE3 DLDSGDFQPAAHYSGAEKQ-IWWTGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLA
       : ..: :. . .:.:. .. .  .:: . :  : :: : : :.:: .::.:..  :::: 
XP_005 DPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLE
           420       430       440       450       460       470   

       460       470       480       490       500       510       
pF1KE3 IVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTL
       ..::  ..... . . ::.:.::..::::::: :::.:::... .. ::. ..:::::::
XP_005 VLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTL
           480       490       500       510       520       530   

       520       530       540       550       560       570       
pF1KE3 SLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFN
       : :::.::::.:..:..:.::.:...:                          ::::: .
XP_005 SGRGSNYGSLLTTEGQFQVFAKTAYYK--------------------------MRDVQNE
           540       550       560                                 

       580       590       600       610       620       630       
pF1KE3 HLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNS
       :::::.::: :::::::.:::::::::::::::.::.::::::::: ::.:::: ::::.
XP_005 HLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNG
       570       580       590       600       610       620       

       640       650       660       670       680       690       
pF1KE3 IISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPL
        : :::.:::::::::.::::::::::: :::.  .:...:..::::::::::::     
XP_005 AICSHGNLKSSNCVVDGRFVLKITDYGLESFRDL-DPEQGHTVYAKKLWTAPELLRMASP
       630       640       650       660        670       680      

       700       710       720       730       740       750       
pF1KE3 PTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQL
       :. : : .::::::::::::::::: :..::::::::::...:  :..: ::::.   . 
XP_005 PVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSH
        690       700       710       720       730       740      

       760       770       780       790       800       810       
pF1KE3 NEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVE
        ::: :::.::::.:: ::: : ::.  .:.::.:....:::::: ::::::::::.:::
XP_005 LEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVE
        750       760       770       780       790       800      

       820       830       840       850       860       870       
pF1KE3 ERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAES
        810       820       830       840       850       860      

       880       890       900       910       920       930       
pF1KE3 TPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALAL
       ::::::::::::::::::.::::::::::::::::::::::: :::. :: :.:::::::
XP_005 TPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALAL
        870       880       890       900       910       920      

       940       950       960       970       980       990       
pF1KE3 LDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQAL
       :::: ::::::::..:::::::.::::::::::::::::::::::::::::::::::.::
XP_005 LDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEAL
        930       940       950       960       970       980      

      1000      1010      1020      1030      1040       
pF1KE3 KIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKGPPGLL
       :::.:: :: .:.:.: :.::::::::::::::.:::::::::       
XP_005 KIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG 
        990      1000      1010      1020      1030      

>>XP_024303328 (OMIM: 108961,602875,615923,616255) atria  (632 aa)
 initn: 2418 init1: 2418 opt: 2427  Z-score: 1105.7  bits: 215.5 E(91609): 8.1e-55
Smith-Waterman score: 3717; 91.5% identity (91.6% similar) in 632 aa overlap (469-1047:1-632)

      440       450       460       470       480       490        
pF1KE3 CAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEE
                                     ::::::::::::::::::::::::::::::
XP_024                               MFGVSSFLIFRKLMLEKELASMLWRIRWEE
                                             10        20        30

      500       510       520       530       540       550        
pF1KE3 LQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRI
               40        50        60        70        80        90

      560       570       580       590       600       610        
pF1KE3 ELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINLDWM
              100       110       120       130       140       150

      620       630       640       650       660       670        
pF1KE3 FRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSH
              160       170       180       190       200       210

      680                                                          
pF1KE3 ALYA-----------------------------------------------------KKL
       ::::                                                     .::
XP_024 ALYASEAHPHNPLFILLLFPPRDGGRGRWSDSNIGMSPGGLGGAPFRGTWPAGFLFSEKL
              220       230       240       250       260       270

         690       700       710       720       730       740     
pF1KE3 WTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 WTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQR
              280       290       300       310       320       330

         750       760       770       780       790       800     
pF1KE3 PYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLLLRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLLLRM
              340       350       360       370       380       390

         810       820       830       840       850       860     
pF1KE3 EQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFS
              400       410       420       430       440       450

         870       880       890       900       910       920     
pF1KE3 DIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQR
              460       470       480       490       500       510

         930       940       950       960       970       980     
pF1KE3 HAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 HAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVN
              520       530       540       550       560       570

         990      1000      1010      1020      1030      1040     
pF1KE3 TASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKGPPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKGPPG
              580       590       600       610       620       630

         
pF1KE3 LL
       ::
XP_024 LL
         

>>XP_024303327 (OMIM: 108961,602875,615923,616255) atria  (635 aa)
 initn: 2475 init1: 2418 opt: 2427  Z-score: 1105.7  bits: 215.5 E(91609): 8.1e-55
Smith-Waterman score: 3701; 91.0% identity (91.2% similar) in 635 aa overlap (469-1047:1-635)

      440       450       460       470          480       490     
pF1KE3 CAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFR---KLMLEKELASMLWRIR
                                     :::::::::::   ::::::::::::::::
XP_024                               MFGVSSFLIFRPYRKLMLEKELASMLWRIR
                                             10        20        30

         500       510       520       530       540       550     
pF1KE3 WEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 WEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNK
               40        50        60        70        80        90

         560       570       580       590       600       610     
pF1KE3 KRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPRGSLQDILENDSINL
              100       110       120       130       140       150

         620       630       640       650       660       670     
pF1KE3 DWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPD
              160       170       180       190       200       210

         680                                                       
pF1KE3 DSHALYA-----------------------------------------------------
       :::::::                                                     
XP_024 DSHALYASEAHPHNPLFILLLFPPRDGGRGRWSDSNIGMSPGGLGGAPFRGTWPAGFLFS
              220       230       240       250       260       270

            690       700       710       720       730       740  
pF1KE3 KKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRN
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRN
              280       290       300       310       320       330

            750       760       770       780       790       800  
pF1KE3 GQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLL
              340       350       360       370       380       390

            810       820       830       840       850       860  
pF1KE3 LRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTI
              400       410       420       430       440       450

            870       880       890       900       910       920  
pF1KE3 YFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 YFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRN
              460       470       480       490       500       510

            930       940       950       960       970       980  
pF1KE3 GQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGD
              520       530       540       550       560       570

            990      1000      1010      1020      1030      1040  
pF1KE3 TVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKG
              580       590       600       610       620       630

            
pF1KE3 PPGLL
       :::::
XP_024 PPGLL
            

>>XP_024303326 (OMIM: 108961,602875,615923,616255) atria  (774 aa)
 initn: 3450 init1: 2418 opt: 2427  Z-score: 1104.9  bits: 215.6 E(91609): 9e-55
Smith-Waterman score: 4676; 92.6% identity (92.8% similar) in 774 aa overlap (330-1047:1-774)

     300       310       320       330       340       350         
pF1KE3 EPPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTRE
                                     ::::::::::::::::::::::::::::::
XP_024                               MNLIAGCFYDGILLYAEVLNETIQEGGTRE
                                             10        20        30

     360       370       380       390       400       410         
pF1KE3 DGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIW
               40        50        60        70        80        90

     420       430       440       450       460       470         
pF1KE3 WTGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 WTGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFR
              100       110       120       130       140       150

        480       490       500       510       520       530      
pF1KE3 ---KLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQI
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PYRKLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQI
              160       170       180       190       200       210

        540       550       560       570       580       590      
pF1KE3 FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVT
              220       230       240       250       260       270

        600       610       620       630       640       650      
pF1KE3 EYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRF
              280       290       300       310       320       330

        660       670       680                                    
pF1KE3 VLKITDYGLASFRSTAEPDDSHALYA----------------------------------
       ::::::::::::::::::::::::::                                  
XP_024 VLKITDYGLASFRSTAEPDDSHALYASEAHPHNPLFILLLFPPRDGGRGRWSDSNIGMSP
              340       350       360       370       380       390

                               690       700       710       720   
pF1KE3 -------------------KKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGP
                          .::::::::::::::::::::::::::::::::::::::::
XP_024 GGLGGAPFRGTWPAGFLFSEKLWTAPELLSGNPLPTTGMQKADVYSFGIILQEIALRSGP
              400       410       420       430       440       450

           730       740       750       760       770       780   
pF1KE3 FYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAERPDFGQIK
              460       470       480       490       500       510

           790       800       810       820       830       840   
pF1KE3 GFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVA
              520       530       540       550       560       570

           850       860       870       880       890       900   
pF1KE3 EQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNFDVY
              580       590       600       610       620       630

           910       920       930       940       950       960   
pF1KE3 KVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRLRIGVHTG
              640       650       660       670       680       690

           970       980       990      1000      1010      1020   
pF1KE3 PVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDV
              700       710       720       730       740       750

          1030      1040       
pF1KE3 EMKGKGKMRTYWLLGERKGPPGLL
       ::::::::::::::::::::::::
XP_024 EMKGKGKMRTYWLLGERKGPPGLL
              760       770    




1047 residues in 1 query   sequences
64848753 residues in 91609 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Aug 27 19:45:54 2018 done: Mon Aug 27 19:45:56 2018
 Total Scan time:  6.810 Total Display time:  0.280

Function used was FASTA [36.3.4 Apr, 2011]
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