Result of FASTA (ccds) for pF1KE1971
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1971, 538 aa
  1>>>pF1KE1971     538 - 538 aa - 538 aa
Library: human.CCDS.faa
  18921897 residues in 33420 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8464+/-0.000982; mu= 16.1218+/- 0.059
 mean_var=81.7190+/-16.253, 0's: 0 Z-trim(104.7): 52  B-trim: 10 in 1/48
 Lambda= 0.141877
 statistics sampled from 8117 (8164) to 8117 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.244), width:  16
 Scan time:  1.590

The best scores are:                                      opt bits E(33420)
CCDS42798.1 CASP8 gene_id:841|Hs109|chr2           ( 538) 3577 742.3 3.3e-214
CCDS2342.1 CASP8 gene_id:841|Hs109|chr2            ( 479) 3182 661.5 6.5e-190
CCDS2343.1 CASP8 gene_id:841|Hs109|chr2            ( 464) 1958 410.9 1.7e-114
CCDS42799.1 CASP8 gene_id:841|Hs109|chr2           ( 496) 1956 410.5 2.3e-114
CCDS2345.1 CASP8 gene_id:841|Hs109|chr2            ( 235) 1250 265.8   4e-71
CCDS2340.1 CASP10 gene_id:843|Hs109|chr2           ( 522)  732 160.0 6.4e-39
CCDS2339.1 CASP10 gene_id:843|Hs109|chr2           ( 479)  721 157.7 2.8e-38
CCDS56159.1 CASP10 gene_id:843|Hs109|chr2          ( 455)  657 144.6 2.4e-34
CCDS7580.1 CASP7 gene_id:840|Hs109|chr10           ( 336)  568 126.3 5.6e-29
CCDS58096.1 CASP7 gene_id:840|Hs109|chr10          ( 278)  566 125.9 6.4e-29
CCDS7581.1 CASP7 gene_id:840|Hs109|chr10           ( 303)  565 125.7 7.9e-29
CCDS73200.1 CASP7 gene_id:840|Hs109|chr10          ( 388)  565 125.8 9.7e-29
CCDS56160.1 CASP10 gene_id:843|Hs109|chr2          ( 478)  544 121.5 2.3e-27
CCDS2338.1 CASP10 gene_id:843|Hs109|chr2           ( 521)  531 118.9 1.5e-26
CCDS3684.1 CASP6 gene_id:839|Hs109|chr4            ( 293)  451 102.3 8.2e-22
CCDS5879.1 CASP2 gene_id:835|Hs109|chr7            ( 452)  421 96.3 8.2e-20
CCDS2337.1 CFLAR gene_id:8837|Hs109|chr2           ( 480)  411 94.3 3.6e-19
CCDS77505.1 CFLAR gene_id:8837|Hs109|chr2          ( 462)  406 93.2 7.1e-19
CCDS3836.1 CASP3 gene_id:836|Hs109|chr4            ( 277)  403 92.5 7.1e-19
CCDS159.2 CASP9 gene_id:842|Hs109|chr1             ( 333)  391 90.1 4.5e-18
CCDS158.1 CASP9 gene_id:842|Hs109|chr1             ( 416)  391 90.2 5.4e-18
CCDS87283.1 CASP3 gene_id:836|Hs109|chr4           ( 182)  363 84.2 1.5e-16
CCDS3685.1 CASP6 gene_id:839|Hs109|chr4            ( 204)  343 80.2 2.7e-15
CCDS12323.1 CASP14 gene_id:23581|Hs109|chr19       ( 242)  315 74.5 1.7e-13
CCDS56158.1 CFLAR gene_id:8837|Hs109|chr2          ( 384)  302 71.9 1.5e-12
CCDS59436.1 CFLAR gene_id:8837|Hs109|chr2          ( 366)  297 70.9   3e-12
CCDS77506.1 CASP10 gene_id:843|Hs109|chr2          ( 247)  292 69.8 4.4e-12


>>CCDS42798.1 CASP8 gene_id:841|Hs109|chr2                (538 aa)
 initn: 3577 init1: 3577 opt: 3577  Z-score: 3959.4  bits: 742.3 E(33420): 3.3e-214
Smith-Waterman score: 3577; 99.8% identity (100.0% similar) in 538 aa overlap (1-538:1-538)

               10        20        30        40        50        60
pF1KE1 MEGGRRARVVIESRRNFFLGAFPTPFPAEHVELGRLGDSETAMVPGKGGADYILLPFKKM
       :::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MEGGRRARVVIESKRNFFLGAFPTPFPAEHVELGRLGDSETAMVPGKGGADYILLPFKKM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 FLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 SKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 MDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 GDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWY
              430       440       450       460       470       480

              490       500       510       520       530        
pF1KE1 IQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 IQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
              490       500       510       520       530        

>>CCDS2342.1 CASP8 gene_id:841|Hs109|chr2                 (479 aa)
 initn: 3182 init1: 3182 opt: 3182  Z-score: 3523.2  bits: 661.5 E(33420): 6.5e-190
Smith-Waterman score: 3182; 100.0% identity (100.0% similar) in 479 aa overlap (60-538:1-479)

      30        40        50        60        70        80         
pF1KE1 HVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYI
                                     ::::::::::::::::::::::::::::::
CCDS23                               MDFSRNLYDIGEQLDSEDLASLKFLSLDYI
                                             10        20        30

      90       100       110       120       130       140         
pF1KE1 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
               40        50        60        70        80        90

     150       160       170       180       190       200         
pF1KE1 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
              100       110       120       130       140       150

     210       220       230       240       250       260         
pF1KE1 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
              160       170       180       190       200       210

     270       280       290       300       310       320         
pF1KE1 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
              220       230       240       250       260       270

     330       340       350       360       370       380         
pF1KE1 TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQE
              280       290       300       310       320       330

     390       400       410       420       430       440         
pF1KE1 APIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 APIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQT
              340       350       360       370       380       390

     450       460       470       480       490       500         
pF1KE1 RYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 RYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV
              400       410       420       430       440       450

     510       520       530        
pF1KE1 SNKDDKKNMGKQMPQPTFTLRKKLVFPSD
       :::::::::::::::::::::::::::::
CCDS23 SNKDDKKNMGKQMPQPTFTLRKKLVFPSD
              460       470         

>>CCDS2343.1 CASP8 gene_id:841|Hs109|chr2                 (464 aa)
 initn: 1953 init1: 1953 opt: 1958  Z-score: 2169.4  bits: 410.9 E(33420): 1.7e-114
Smith-Waterman score: 3046; 96.9% identity (96.9% similar) in 479 aa overlap (60-538:1-464)

      30        40        50        60        70        80         
pF1KE1 HVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYI
                                     ::::::::::::::::::::::::::::::
CCDS23                               MDFSRNLYDIGEQLDSEDLASLKFLSLDYI
                                             10        20        30

      90       100       110       120       130       140         
pF1KE1 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
               40        50        60        70        80        90

     150       160       170       180       190       200         
pF1KE1 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
              100       110       120       130       140       150

     210       220       230       240       250       260         
pF1KE1 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
       :::::::::::::::::::::::::::::::::               ::::::::::::
CCDS23 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSK---------------GEELCGVMTISD
              160       170       180                      190     

     270       280       290       300       310       320         
pF1KE1 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
         200       210       220       230       240       250     

     330       340       350       360       370       380         
pF1KE1 TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQE
         260       270       280       290       300       310     

     390       400       410       420       430       440         
pF1KE1 APIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 APIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQT
         320       330       340       350       360       370     

     450       460       470       480       490       500         
pF1KE1 RYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 RYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV
         380       390       400       410       420       430     

     510       520       530        
pF1KE1 SNKDDKKNMGKQMPQPTFTLRKKLVFPSD
       :::::::::::::::::::::::::::::
CCDS23 SNKDDKKNMGKQMPQPTFTLRKKLVFPSD
         440       450       460    

>>CCDS42799.1 CASP8 gene_id:841|Hs109|chr2                (496 aa)
 initn: 2590 init1: 1953 opt: 1956  Z-score: 2166.8  bits: 410.5 E(33420): 2.3e-114
Smith-Waterman score: 2972; 90.8% identity (90.8% similar) in 511 aa overlap (60-538:1-496)

      30        40        50        60        70        80         
pF1KE1 HVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYI
                                     ::::::::::::::::::::::::::::::
CCDS42                               MDFSRNLYDIGEQLDSEDLASLKFLSLDYI
                                             10        20        30

      90       100       110       120       130       140         
pF1KE1 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
               40        50        60        70        80        90

     150       160                                       170       
pF1KE1 QTPGRAQISAYR--------------------------------VMLYQISEEVSRSELR
       ::::::::::::                                ::::::::::::::::
CCDS42 QTPGRAQISAYRFHFCRMSWAEANSQCQTQSVPFWRRVDHLLIRVMLYQISEEVSRSELR
              100       110       120       130       140       150

       180       190       200       210       220       230       
pF1KE1 SFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDY
              160       170       180       190       200       210

       240       250       260       270       280       290       
pF1KE1 EEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLI
       :::::               ::::::::::::::::::::::::::::::::::::::::
CCDS42 EEFSK---------------GEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLI
                             220       230       240       250     

       300       310       320       330       340       350       
pF1KE1 INNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 INNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKI
         260       270       280       290       300       310     

       360       370       380       390       400       410       
pF1KE1 YQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 YQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQ
         320       330       340       350       360       370     

       420       430       440       450       460       470       
pF1KE1 ACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 ACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEG
         380       390       400       410       420       430     

       480       490       500       510       520       530       
pF1KE1 TWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPS
         440       450       460       470       480       490     

        
pF1KE1 D
       :
CCDS42 D
        

>>CCDS2345.1 CASP8 gene_id:841|Hs109|chr2                 (235 aa)
 initn: 1250 init1: 1250 opt: 1250  Z-score: 1390.6  bits: 265.8 E(33420): 4e-71
Smith-Waterman score: 1250; 100.0% identity (100.0% similar) in 198 aa overlap (60-257:1-198)

      30        40        50        60        70        80         
pF1KE1 HVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYI
                                     ::::::::::::::::::::::::::::::
CCDS23                               MDFSRNLYDIGEQLDSEDLASLKFLSLDYI
                                             10        20        30

      90       100       110       120       130       140         
pF1KE1 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
               40        50        60        70        80        90

     150       160       170       180       190       200         
pF1KE1 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
              100       110       120       130       140       150

     210       220       230       240       250       260         
pF1KE1 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
       ::::::::::::::::::::::::::::::::::::::::::::::::            
CCDS23 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNDFGQSLPNEKQT
              160       170       180       190       200       210

     270       280       290       300       310       320         
pF1KE1 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
                                                                   
CCDS23 SGILSDHQQSQFCKSTGESAQTSQH                                   
              220       230                                        

>>CCDS2340.1 CASP10 gene_id:843|Hs109|chr2                (522 aa)
 initn: 984 init1: 362 opt: 732  Z-score: 812.4  bits: 160.0 E(33420): 6.4e-39
Smith-Waterman score: 988; 37.8% identity (62.2% similar) in 519 aa overlap (59-536:17-514)

       30        40        50        60        70        80        
pF1KE1 EHVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDY
                                     :..: ..:  :  .:  .:. .:::: .  
CCDS23               MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGL
                             10        20        30        40      

       90       100       110       120       130       140        
pF1KE1 IPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERE
       .:..: :  ..:  .:..:  . .: : .  :: :::. : :   :. .::  :::.:: 
CCDS23 VPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLY-IIRQKKLLQHLNCTKEEVERL
         50        60        70        80         90       100     

      150       160       170       180       190       200        
pF1KE1 LQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKR
       :  : : ..: .: .::..:: ..  .:... :::.. . :     .:. :...  .::.
CCDS23 L--PTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKT----EMTSLSFLAFLEKQ
           110       120       130       140           150         

      210       220       230                 240                  
pF1KE1 VILGEGKLDILKRVCAQINKSLLKIINDYEE----------FSKERSSS-----------
         . : .:  :. .:  .  .::. :. :..           .::  :            
CCDS23 GKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTD
     160       170       180       190       200       210         

           250              260              270       280         
pF1KE1 ----LEGSPDEF-------SNGEELC-GVMTISD------SPREQDSESQTLDK-VYQMK
           ::. :.:        :::..   :. .. .      :    .::..:    ::.:.
CCDS23 VKTFLEALPQESWQNKHAGSNGNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMN
     220       230       240       250       260       270         

      290       300       310       320       330       340        
pF1KE1 SKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTV
        . :: :.:.:::.:.          :..::.::: ::  :. .:. : : .. :.. : 
CCDS23 RNHRGLCVIVNNHSFT----------SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTK
     280       290                 300       310       320         

      350       360        370       380       390       400       
pF1KE1 EQIYEILKIYQLMD-HSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSL
        ..  .:.  .    :.. :::. :::.::  : .:..:    :: :. :.::.:.:: :
CCDS23 VEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRL
     330       340       350       360       370       380         

       410       420       430       440       450       460       
pF1KE1 AGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNN
       : :::.::::::::.. : .. .:.:. . :  :.  .: :   :: :::::::.::: .
CCDS23 AEKPKLFFIQACQGEEIQPSVSIEADALN-P--EQAPTSLQDS-IPAEADFLLGLATVPG
     390       400       410          420        430       440     

       470       480       490       500       510       520       
pF1KE1 CVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTF
        ::.:.  ::.:::::::. :..  :: .:::.::: :: .:: . ::..  ::::::.:
CCDS23 YVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVNDDVSRRVDKQGTKKQMPQPAF
         450       460       470       480       490       500     

       530              
pF1KE1 TLRKKLVFPSD      
       :::::::::        
CCDS23 TLRKKLVFPVPLDALSL
         510       520  

>>CCDS2339.1 CASP10 gene_id:843|Hs109|chr2                (479 aa)
 initn: 984 init1: 362 opt: 721  Z-score: 800.8  bits: 157.7 E(33420): 2.8e-38
Smith-Waterman score: 1038; 39.3% identity (65.4% similar) in 483 aa overlap (59-536:17-471)

       30        40        50        60        70        80        
pF1KE1 EHVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDY
                                     :..: ..:  :  .:  .:. .:::: .  
CCDS23               MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGL
                             10        20        30        40      

       90       100       110       120       130       140        
pF1KE1 IPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERE
       .:..: :  ..:  .:..:  . .: : .  :: :::. : :   :. .::  :::.:: 
CCDS23 VPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLY-IIRQKKLLQHLNCTKEEVERL
         50        60        70        80         90       100     

      150       160       170       180       190       200        
pF1KE1 LQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKR
       :  : : ..: .: .::..:: ..  .:... :::.. . :     .:. :...  .::.
CCDS23 L--PTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKT----EMTSLSFLAFLEKQ
           110       120       130       140           150         

      210       220       230       240       250           260    
pF1KE1 VILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSP-D---EFSNGEELCGV
         . : .:  :. .:  .  .::. :   :....:.. ..   : :   :  .:::    
CCDS23 GKIDEDNLTCLEDLCKTVVPKLLRNI---EKYKREKAIQIVTPPVDKEAESYQGEE----
     160       170       180          190       200       210      

          270       280       290       300       310       320    
pF1KE1 MTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHL
         .:..  .   :.     ::.:. . :: :.:.:::.:.          :..::.::: 
CCDS23 ELVSQTDVKTFLEALPRAAVYRMNRNHRGLCVIVNNHSFT----------SLKDRQGTHK
            220       230       240       250                 260  

          330       340       350       360        370       380   
pF1KE1 DAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMD-HSNMDCFICCILSHGDKGIIY
       ::  :. .:. : : .. :.. :  ..  .:.  .    :.. :::. :::.::  : .:
CCDS23 DAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVY
            270       280       290       300       310       320  

           390       400       410       420       430       440   
pF1KE1 GTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMD
       ..:    :: :. :.::.:.:: :: :::.::::::::.. : .. .:.:. . :  :. 
CCDS23 SSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALN-P--EQA
            330       340       350       360       370            

           450       460       470       480       490       500   
pF1KE1 LSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILT
        .: :   :: :::::::.::: . ::.:.  ::.:::::::. :..  :: .:::.:::
CCDS23 PTSLQDS-IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILT
     380        390       400       410       420       430        

           510       520       530              
pF1KE1 EVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD      
        :: .:: . ::..  ::::::.::::::::::        
CCDS23 AVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
      440       450       460       470         

>>CCDS56159.1 CASP10 gene_id:843|Hs109|chr2               (455 aa)
 initn: 823 init1: 362 opt: 657  Z-score: 730.4  bits: 144.6 E(33420): 2.4e-34
Smith-Waterman score: 889; 36.1% identity (62.6% similar) in 479 aa overlap (59-536:17-447)

       30        40        50        60        70        80        
pF1KE1 EHVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDY
                                     :..: ..:  :  .:  .:. .:::: .  
CCDS56               MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGL
                             10        20        30        40      

       90       100       110       120       130       140        
pF1KE1 IPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERE
       .:..: :  ..:  .:..:  . .: : .  :: :::. : :   :. .::  :::.:: 
CCDS56 VPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLY-IIRQKKLLQHLNCTKEEVERL
         50        60        70        80         90       100     

      150       160       170       180       190       200        
pF1KE1 LQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKR
       :  : : ..: .: .::..:: ..  .:... :::.. . :     .:. :...  .::.
CCDS56 L--PTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKT----EMTSLSFLAFLEKQ
           110       120       130       140           150         

      210       220       230       240       250       260        
pF1KE1 VILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTIS
         . : .:  :. .:  .  .::. :   :....:..                   . : 
CCDS56 GKIDEDNLTCLEDLCKTVVPKLLRNI---EKYKREKA-------------------IQIV
     160       170       180          190                          

      270       280       290       300       310       320        
pF1KE1 DSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGA
         : ....::      ::      :   .... .     : .:. .: .....   .   
CCDS56 TPPVDKEAES------YQ------GEEELVSQTDVKTFLEALPQ-ESWQNKHAGSNEI--
       200                   210       220        230       240    

      330       340       350       360        370       380       
pF1KE1 LTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMD-HSNMDCFICCILSHGDKGIIYGTDG
       :. .:. : : .. :.. :  ..  .:.  .    :.. :::. :::.::  : .:..: 
CCDS56 LSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDE
            250       260       270       280       290       300  

       390       400       410       420       430       440       
pF1KE1 QEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSP
          :: :. :.::.:.:: :: :::.::::::::.. : .. .:.:. . :  :.  .: 
CCDS56 ALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALN-P--EQAPTSL
            310       320       330       340       350            

       450       460       470       480       490       500       
pF1KE1 QTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNY
       :   :: :::::::.::: . ::.:.  ::.:::::::. :..  :: .:::.::: :: 
CCDS56 QDS-IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVND
     360        370       380       390       400       410        

       510       520       530              
pF1KE1 EVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD      
       .:: . ::..  ::::::.::::::::::        
CCDS56 DVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
      420       430       440       450     

>>CCDS7580.1 CASP7 gene_id:840|Hs109|chr10                (336 aa)
 initn: 508 init1: 218 opt: 568  Z-score: 633.9  bits: 126.3 E(33420): 5.6e-29
Smith-Waterman score: 568; 36.4% identity (62.7% similar) in 327 aa overlap (222-535:26-334)

             200       210       220       230       240           
pF1KE1 LDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSS---SL
                                     .::.   ..    .  :: . : :.   :.
CCDS75      MDCVGWPPGRKWHLEKNTSCGGSSGICASYVTQMADDQGCIEEQGVEDSANEDSV
                    10        20        30        40        50     

      250       260       270       280           290       300    
pF1KE1 EGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKV----YQMKSKPRGYCLIINNHNFA
       ...::. :    : .    . . :   : . : :.:    :.:. .  : :.::::.:: 
CCDS75 DAKPDRSSFVPSLFSKKKKNVTMR---SIKTTRDRVPTYQYNMNFEKLGKCIIINNKNF-
          60        70           80        90       100       110  

          310       320       330       340       350       360    
pF1KE1 KAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHS
          .::  .     ::::  :: ::   :. : :..  ..::.  .. ..::  .  ::.
CCDS75 ---DKVTGMGV---RNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT
                   120       130       140       150       160     

          370       380       390       400       410       420    
pF1KE1 NMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNY
       :  :: : .::::....::: ::  .:: .::..: : .: .:  :::.::::::.: . 
CCDS75 NAACFACILLSHGEENVIYGKDGV-TPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTEL
         170       180        190       200       210       220    

          430       440       450       460       470       480    
pF1KE1 QKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL
       . ::  ..::   :  . : ..:. . :: :::::....:: .  :.:.:..:.:..:.:
CCDS75 DDGI--QADS--GPINDTD-ANPRYK-IPVEADFLFAYSTVPGYYSWRSPGRGSWFVQAL
            230          240        250       260       270        

          490       500            510        520       530        
pF1KE1 CQSLRERCPRGDDILTILTEVNYEV-----SNKDDKK-NMGKQMPQPTFTLRKKLVFPSD
       :. :.:.  .  .:. :::.:: .:     :..:: . .  ::.:  .  : :.: :   
CCDS75 CSILEEH-GKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ 
      280        290       300       310       320       330       

>>CCDS58096.1 CASP7 gene_id:840|Hs109|chr10               (278 aa)
 initn: 508 init1: 218 opt: 566  Z-score: 632.9  bits: 125.9 E(33420): 6.4e-29
Smith-Waterman score: 566; 37.2% identity (65.6% similar) in 288 aa overlap (263-535:4-276)

            240       250       260       270            280       
pF1KE1 IINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQ-----TLDKV---
                                     :... .:. ... . ..     : :.:   
CCDS58                            MQRGLFSDGDTSKKKKNVTMRSIKTTRDRVPTY
                                          10        20        30   

           290       300       310       320       330       340   
pF1KE1 -YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPH
        :.:. .  : :.::::.::        :. ..  ::::  :: ::   :. : :..  .
CCDS58 QYNMNFEKLGKCIIINNKNF-------DKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVY
            40        50               60        70        80      

           350       360       370       380       390       400   
pF1KE1 DDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLK
       .::.  .. ..::  .  ::.:  :: : .::::....::: ::  .:: .::..: : .
CCDS58 NDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGV-TPIKDLTAHFRGDR
         90       100       110       120       130        140     

           410       420       430       440       450       460   
pF1KE1 CPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMA
       : .:  :::.::::::.: . . ::  ..::   :  . : ..:. . :: :::::....
CCDS58 CKTLLEKPKLFFIQACRGTELDDGI--QADS--GPINDTD-ANPRYK-IPVEADFLFAYS
         150       160       170           180         190         

           470       480       490       500            510        
pF1KE1 TVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV-----SNKDDKK-N
       :: .  :.:.:..:.:..:.::. :.:.  .  .:. :::.:: .:     :..:: . .
CCDS58 TVPGYYSWRSPGRGSWFVQALCSILEEH-GKDLEIMQILTRVNDRVARHFESQSDDPHFH
     200       210       220        230       240       250        

       520       530        
pF1KE1 MGKQMPQPTFTLRKKLVFPSD
         ::.:  .  : :.: :   
CCDS58 EKKQIPCVVSMLTKELYFSQ 
      260       270         




538 residues in 1 query   sequences
18921897 residues in 33420 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:32:06 2019 done: Thu Oct 24 21:32:06 2019
 Total Scan time:  1.590 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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