Result of FASTA (omim) for pF1KE2530
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2530, 3122 aa
  1>>>pF1KE2530     3122 - 3122 aa - 3122 aa
Library: /omim/omim.rfq.tfa
  64092750 residues in 91774 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.3064+/-0.000672; mu= 3.4374+/- 0.041
 mean_var=449.4603+/-91.155, 0's: 0 Z-trim(115.1): 265  B-trim: 0 in 0/53
 Lambda= 0.060496
 statistics sampled from 26089 (26350) to 26089 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.287), width:  16
 Scan time: 13.940

The best scores are:                                      opt bits E(91774)
NP_000417 (OMIM: 156225,607855,618138) laminin sub (3122) 21710 1913.1       0
NP_001073291 (OMIM: 156225,607855,618138) laminin  (3118) 21664 1909.1       0
XP_016866341 (OMIM: 156225,607855,618138) laminin  (2587) 14830 1312.5       0
XP_005267038 (OMIM: 156225,607855,618138) laminin  (3210) 14830 1312.7       0
XP_016866340 (OMIM: 156225,607855,618138) laminin  (3212) 14830 1312.7       0
XP_011534122 (OMIM: 156225,607855,618138) laminin  (3208) 14805 1310.5       0
XP_005267039 (OMIM: 156225,607855,618138) laminin  (3206) 14789 1309.1       0
XP_016866342 (OMIM: 156225,607855,618138) laminin  (1916) 7333 658.1 4.4e-187
NP_005550 (OMIM: 150320,615960) laminin subunit al (3075) 7179 644.9 6.6e-183
XP_011524284 (OMIM: 226650,226700,245660,600805) l (3243) 1426 142.8 9.6e-32
NP_001121189 (OMIM: 226650,226700,245660,600805) l (3277) 1426 142.8 9.7e-32
NP_937762 (OMIM: 226650,226700,245660,600805) lami (3333) 1426 142.8 9.8e-32
XP_011524282 (OMIM: 226650,226700,245660,600805) l (3336) 1426 142.8 9.8e-32
XP_011524281 (OMIM: 226650,226700,245660,600805) l (3339) 1426 142.8 9.8e-32
XP_011524280 (OMIM: 226650,226700,245660,600805) l (3342) 1426 142.8 9.8e-32
XP_011524283 (OMIM: 226650,226700,245660,600805) l (3298) 1398 140.4 5.3e-31
NP_001289925 (OMIM: 226650,226700,245660,600805) l ( 488) 1356 135.7   2e-30
XP_006723861 (OMIM: 601033) laminin subunit alpha- (2300) 1329 134.1 2.8e-29
NP_005551 (OMIM: 601033) laminin subunit alpha-5 p (3695) 1329 134.4 3.7e-29
XP_006723859 (OMIM: 601033) laminin subunit alpha- (3700) 1329 134.4 3.7e-29
XP_011527121 (OMIM: 601033) laminin subunit alpha- (3609) 1322 133.8 5.6e-29
XP_011527120 (OMIM: 601033) laminin subunit alpha- (3654) 1322 133.8 5.6e-29
NP_002284 (OMIM: 150290) laminin subunit gamma-1 p (1609) 1309 132.2 7.4e-29
XP_016881232 (OMIM: 226650,226700,245660,600805) l (2626) 1162 119.6 7.3e-25
NP_002282 (OMIM: 150240,615191) laminin subunit be (1786) 1056 110.2 3.5e-22
XP_016867690 (OMIM: 150240,615191) laminin subunit (1810) 1056 110.2 3.5e-22
XP_016867691 (OMIM: 150240,615191) laminin subunit (1212) 1007 105.7 5.3e-21
NP_001278789 (OMIM: 142461,224410,255800) basement (4392)  952 101.6 3.3e-19
XP_016856610 (OMIM: 142461,224410,255800) basement (4439)  952 101.6 3.3e-19
XP_016856609 (OMIM: 142461,224410,255800) basement (4456)  952 101.6 3.3e-19
XP_011539620 (OMIM: 142461,224410,255800) basement (4574)  952 101.6 3.4e-19
NP_005520 (OMIM: 142461,224410,255800) basement me (4391)  951 101.5 3.5e-19
XP_016856611 (OMIM: 142461,224410,255800) basement (4438)  951 101.5 3.5e-19
XP_005265184 (OMIM: 150325,609049,614199) laminin  (1798)  927 98.9 8.6e-19
NP_002283 (OMIM: 150325,609049,614199) laminin sub (1798)  927 98.9 8.6e-19
XP_011514282 (OMIM: 616380) laminin subunit beta-4 (1564)  800 87.8 1.7e-15
XP_016867369 (OMIM: 616380) laminin subunit beta-4 (1567)  800 87.8 1.7e-15
XP_011514281 (OMIM: 616380) laminin subunit beta-4 (1703)  800 87.8 1.8e-15
XP_011514280 (OMIM: 616380) laminin subunit beta-4 (1723)  800 87.8 1.8e-15
XP_016867368 (OMIM: 616380) laminin subunit beta-4 (1753)  800 87.8 1.8e-15
NP_031382 (OMIM: 616380) laminin subunit beta-4 is (1761)  800 87.8 1.8e-15
NP_001304975 (OMIM: 616380) laminin subunit beta-4 (1761)  800 87.8 1.8e-15
XP_011514277 (OMIM: 616380) laminin subunit beta-4 (1772)  800 87.8 1.9e-15
NP_001304976 (OMIM: 616380) laminin subunit beta-4 (1101)  760 84.1 1.5e-14
XP_016881233 (OMIM: 226650,226700,245660,600805) l (1856)  755 83.9 2.9e-14
NP_001304977 (OMIM: 616380) laminin subunit beta-4 ( 772)  713 79.8 2.1e-13
NP_000218 (OMIM: 226650,226700,245660,600805) lami (1724)  644 74.2 2.3e-11
XP_016866343 (OMIM: 600133,615235) laminin subunit (1816)  636 73.5 3.8e-11
NP_001098677 (OMIM: 600133,615235) laminin subunit (1816)  636 73.5 3.8e-11
NP_002281 (OMIM: 600133,615235) laminin subunit al (1816)  636 73.5 3.8e-11


>>NP_000417 (OMIM: 156225,607855,618138) laminin subunit  (3122 aa)
 initn: 21710 init1: 21710 opt: 21710  Z-score: 10259.3  bits: 1913.1 E(91774):    0
Smith-Waterman score: 21710; 100.0% identity (100.0% similar) in 3122 aa overlap (1-3122:1-3122)

               10        20        30        40        50        60
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KE2 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KE2 HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KE2 FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KE2 EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KE2 NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KE2 TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KE2 ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KE2 AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KE2 ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KE2 NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KE2 EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KE2 DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KE2 VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KE2 IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440      2450      2460
pF1KE2 SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
             2410      2420      2430      2440      2450      2460

             2470      2480      2490      2500      2510      2520
pF1KE2 DLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
             2470      2480      2490      2500      2510      2520

             2530      2540      2550      2560      2570      2580
pF1KE2 CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
             2530      2540      2550      2560      2570      2580

             2590      2600      2610      2620      2630      2640
pF1KE2 TGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
             2590      2600      2610      2620      2630      2640

             2650      2660      2670      2680      2690      2700
pF1KE2 ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
             2650      2660      2670      2680      2690      2700

             2710      2720      2730      2740      2750      2760
pF1KE2 SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
             2710      2720      2730      2740      2750      2760

             2770      2780      2790      2800      2810      2820
pF1KE2 IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
             2770      2780      2790      2800      2810      2820

             2830      2840      2850      2860      2870      2880
pF1KE2 GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
             2830      2840      2850      2860      2870      2880

             2890      2900      2910      2920      2930      2940
pF1KE2 VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
             2890      2900      2910      2920      2930      2940

             2950      2960      2970      2980      2990      3000
pF1KE2 GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
             2950      2960      2970      2980      2990      3000

             3010      3020      3030      3040      3050      3060
pF1KE2 VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
             3010      3020      3030      3040      3050      3060

             3070      3080      3090      3100      3110      3120
pF1KE2 NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
             3070      3080      3090      3100      3110      3120

         
pF1KE2 AN
       ::
NP_000 AN
         

>>NP_001073291 (OMIM: 156225,607855,618138) laminin subu  (3118 aa)
 initn: 21668 init1: 17394 opt: 21664  Z-score: 10237.6  bits: 1909.1 E(91774):    0
Smith-Waterman score: 21664; 99.8% identity (99.9% similar) in 3122 aa overlap (1-3122:1-3118)

               10        20        30        40        50        60
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE2 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE2 ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE2 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE2 CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNV
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE2 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE2 ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFE
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE2 AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRV
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE2 HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKC
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE2 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KE2 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRG
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KE2 YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KE2 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELK
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KE2 HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGE
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KE2 FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIA
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KE2 EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREA
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KE2 NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KE2 TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFN
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KE2 ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNE
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KE2 AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KE2 ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVK
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KE2 NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKP
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KE2 EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYP
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KE2 DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAMLF
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KE2 VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGT
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KE2 IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKV
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440      2450      2460
pF1KE2 SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGL
             2410      2420      2430      2440      2450      2460

             2470      2480      2490      2500      2510      2520
pF1KE2 DLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
       :::::::::::::::::::    :::::::::::::::::::::::::::::::::::::
NP_001 DLKADDKIYFGGLPTLRNL----RPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKG
             2470          2480      2490      2500      2510      

             2530      2540      2550      2560      2570      2580
pF1KE2 CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQ
       2520      2530      2540      2550      2560      2570      

             2590      2600      2610      2620      2630      2640
pF1KE2 TGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
       ::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVD
       2580      2590      2600      2610      2620      2630      

             2650      2660      2670      2680      2690      2700
pF1KE2 ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPV
       2640      2650      2660      2670      2680      2690      

             2710      2720      2730      2740      2750      2760
pF1KE2 SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALL
       2700      2710      2720      2730      2740      2750      

             2770      2780      2790      2800      2810      2820
pF1KE2 IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRN
       2760      2770      2780      2790      2800      2810      

             2830      2840      2850      2860      2870      2880
pF1KE2 GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILD
       2820      2830      2840      2850      2860      2870      

             2890      2900      2910      2920      2930      2940
pF1KE2 VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQR
       2880      2890      2900      2910      2920      2930      

             2950      2960      2970      2980      2990      3000
pF1KE2 GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFH
       2940      2950      2960      2970      2980      2990      

             3010      3020      3030      3040      3050      3060
pF1KE2 VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSADT
       3000      3010      3020      3030      3040      3050      

             3070      3080      3090      3100      3110      3120
pF1KE2 NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCP
       3060      3070      3080      3090      3100      3110      

         
pF1KE2 AN
       ::
NP_001 AN
         

>>XP_016866341 (OMIM: 156225,607855,618138) laminin subu  (2587 aa)
 initn: 14750 init1: 14750 opt: 14830  Z-score: 7015.0  bits: 1312.5 E(91774):    0
Smith-Waterman score: 17005; 96.6% identity (96.6% similar) in 2587 aa overlap (624-3122:1-2587)

           600       610       620       630       640       650   
pF1KE2 KLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVL
                                     ::::::::::::::::::::::::::::::
XP_016                               MIILEGNDLSISTAQDEVYLHPSEEHTNVL
                                             10        20        30

           660       670       680       690       700       710   
pF1KE2 LLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKEESFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPT
               40        50        60        70        80        90

           720       730       740       750       760       770   
pF1KE2 DGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGEC
              100       110       120       130       140       150

           780       790       800       810       820       830   
pF1KE2 LNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICD
              160       170       180       190       200       210

           840       850       860       870       880       890   
pF1KE2 GCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGT
              220       230       240       250       260       270

           900       910       920       930       940       950   
pF1KE2 TGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCK-
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: 
XP_016 TGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKP
              280       290       300       310       320       330

                                                                   
pF1KE2 ------------------------------------------------------------
                                                                   
XP_016 NMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCVCKSGFVGKQCNLGRQVHQQEEQPRRAQ
              340       350       360       370       380       390

                                       960       970       980     
pF1KE2 ---------------------------AGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC
                                  :::::::::::::::::::::::::::::::::
XP_016 RVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC
              400       410       420       430       440       450

         990      1000      1010      1020      1030      1040     
pF1KE2 WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCA
              460       470       480       490       500       510

        1050      1060      1070      1080      1090      1100     
pF1KE2 PNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNL
              520       530       540       550       560       570

        1110      1120      1130      1140      1150      1160     
pF1KE2 CDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSS
              580       590       600       610       620       630

        1170      1180      1190      1200      1210      1220     
pF1KE2 CYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMR
              640       650       660       670       680       690

        1230      1240      1250      1260      1270      1280     
pF1KE2 EDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHAR
              700       710       720       730       740       750

        1290      1300      1310      1320      1330      1340     
pF1KE2 IIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATY
              760       770       780       790       800       810

        1350      1360      1370      1380      1390      1400     
pF1KE2 GNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNFMRQSRISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQP
              820       830       840       850       860       870

        1410      1420      1430      1440      1450      1460     
pF1KE2 GGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPND
              880       890       900       910       920       930

        1470      1480      1490      1500      1510      1520     
pF1KE2 CQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ
              940       950       960       970       980       990

        1530      1540      1550      1560      1570      1580     
pF1KE2 ECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGD
             1000      1010      1020      1030      1040      1050

        1590      1600      1610      1620      1630      1640     
pF1KE2 LARLEQMVMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LARLEQMVMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVT
             1060      1070      1080      1090      1100      1110

        1650      1660      1670      1680      1690      1700     
pF1KE2 EMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGT
             1120      1130      1140      1150      1160      1170

        1710      1720      1730      1740      1750      1760     
pF1KE2 RDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGEN
             1180      1190      1200      1210      1220      1230

        1770      1780      1790      1800      1810      1820     
pF1KE2 EEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGK
             1240      1250      1260      1270      1280      1290

        1830      1840      1850      1860      1870      1880     
pF1KE2 RQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRK
             1300      1310      1320      1330      1340      1350

        1890      1900      1910      1920      1930      1940     
pF1KE2 LAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEA
             1360      1370      1380      1390      1400      1410

        1950      1960      1970      1980      1990      2000     
pF1KE2 KDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENA
             1420      1430      1440      1450      1460      1470

        2010      2020      2030      2040      2050      2060     
pF1KE2 DARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGL
             1480      1490      1500      1510      1520      1530

        2070      2080      2090      2100      2110      2120     
pF1KE2 KKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELEDNLKK
             1540      1550      1560      1570      1580      1590

        2130      2140      2150      2160      2170      2180     
pF1KE2 NISEIKELINQARKQANSIKVSVSSGGDCIRTYKPEIKKGSYNNIVVNVKTAVADNLLFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NISEIKELINQARKQANSIKVSVSSGGDCIRTYKPEIKKGSYNNIVVNVKTAVADNLLFY
             1600      1610      1620      1630      1640      1650

        2190      2200      2210      2220      2230      2240     
pF1KE2 LGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISV
             1660      1670      1680      1690      1700      1710

        2250      2260      2270      2280      2290      2300     
pF1KE2 RALDGPKASIVPSTHHSTSPPGYTILDVDANAMLFVGGLTGKLKKADAVRVITFTGCMGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALDGPKASIVPSTHHSTSPPGYTILDVDANAMLFVGGLTGKLKKADAVRVITFTGCMGE
             1720      1730      1740      1750      1760      1770

        2310      2320      2330      2340      2350      2360     
pF1KE2 TYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFDGEGYALVSRPIRWYPNISTVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFDGEGYALVSRPIRWYPNISTVM
             1780      1790      1800      1810      1820      1830

        2370      2380      2390      2400      2410      2420     
pF1KE2 FKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSF
             1840      1850      1860      1870      1880      1890

        2430      2440      2450      2460      2470      2480     
pF1KE2 TLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARP
             1900      1910      1920      1930      1940      1950

        2490      2500      2510      2520      2530      2540     
pF1KE2 EVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSFPKPGFVELSPVPID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSFPKPGFVELSPVPID
             1960      1970      1980      1990      2000      2010

        2550      2560      2570      2580      2590      2600     
pF1KE2 VGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGART
       :::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 VGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYAILLNRGRLEVHLSTGART
             2020      2030      2040      2050      2060      2070

        2610      2620      2630      2640      2650      2660     
pF1KE2 MRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVKKLFVGGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDENRRYMQNLTVEQPIEVKKLFVGGA
             2080      2090      2100      2110      2120      2130

        2670      2680      2690      2700      2710      2720     
pF1KE2 PPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKLREDEDGAAPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPEFQPSPLRNIPPFEGCIWNLVINSVPMDFARPVSFKNADIGRCAHQKLREDEDGAAPA
             2140      2150      2160      2170      2180      2190

        2730      2740      2750      2760      2770      2780     
pF1KE2 EIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKN
             2200      2210      2220      2230      2240      2250

        2790      2800      2810      2820      2830      2840     
pF1KE2 RLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDG
             2260      2270      2280      2290      2300      2310

        2850      2860      2870      2880      2890      2900     
pF1KE2 QWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYS
             2320      2330      2340      2350      2360      2370

        2910      2920      2930      2940      2950      2960     
pF1KE2 IDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQRGTYFDGTGFAKAVGGFKVGLDLLVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDGCVRNLHMAEAPADLEQPTSSFHVGTCFANAQRGTYFDGTGFAKAVGGFKVGLDLLVE
             2380      2390      2400      2410      2420      2430

        2970      2980      2990      3000      3010      3020     
pF1KE2 FEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQW
             2440      2450      2460      2470      2480      2490

        3030      3040      3050      3060      3070      3080     
pF1KE2 HKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFR
             2500      2510      2520      2530      2540      2550

        3090      3100      3110      3120  
pF1KE2 GCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCPAN
       :::::::::::::::::::::::::::::::::::::
XP_016 GCIRSLKLTKGTGKPLEVNFAKALELRGVQPVSCPAN
             2560      2570      2580       

>>XP_005267038 (OMIM: 156225,607855,618138) laminin subu  (3210 aa)
 initn: 14750 init1: 14750 opt: 14830  Z-score: 7014.0  bits: 1312.7 E(91774):    0
Smith-Waterman score: 21163; 97.2% identity (97.2% similar) in 3154 aa overlap (57-3122:57-3210)

         30        40        50        60        70        80      
pF1KE2 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
                                     ::::::::::::::::::::::::::::::
XP_005 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
         30        40        50        60        70        80      

         90       100       110       120       130       140      
pF1KE2 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
         90       100       110       120       130       140      

        150       160       170       180       190       200      
pF1KE2 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
        150       160       170       180       190       200      

        210       220       230       240       250       260      
pF1KE2 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
        210       220       230       240       250       260      

        270       280       290       300       310       320      
pF1KE2 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
        270       280       290       300       310       320      

        330       340       350       360       370       380      
pF1KE2 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
        330       340       350       360       370       380      

        390       400       410       420       430       440      
pF1KE2 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
        390       400       410       420       430       440      

        450       460       470       480       490       500      
pF1KE2 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
        450       460       470       480       490       500      

        510       520       530       540       550       560      
pF1KE2 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
        510       520       530       540       550       560      

        570       580       590       600       610       620      
pF1KE2 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
        570       580       590       600       610       620      

        630       640       650       660       670       680      
pF1KE2 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
        630       640       650       660       670       680      

        690       700       710       720       730       740      
pF1KE2 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
        690       700       710       720       730       740      

        750       760       770       780       790       800      
pF1KE2 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
        750       760       770       780       790       800      

        810       820       830       840       850       860      
pF1KE2 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
        810       820       830       840       850       860      

        870       880       890       900       910       920      
pF1KE2 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
        870       880       890       900       910       920      

        930       940       950                                    
pF1KE2 SEVCHSQTGQCECRANVQGQRCDKCK----------------------------------
       ::::::::::::::::::::::::::                                  
XP_005 SEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCV
        930       940       950       960       970       980      

                                                                   
pF1KE2 ------------------------------------------------------AGTFGL
                                                             ::::::
XP_005 CKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGL
        990      1000      1010      1020      1030      1040      

      960       970       980       990      1000      1010        
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
       1050      1060      1070      1080      1090      1100      

     1020      1030      1040      1050      1060      1070        
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
       1110      1120      1130      1140      1150      1160      

     1080      1090      1100      1110      1120      1130        
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
       1170      1180      1190      1200      1210      1220      

     1140      1150      1160      1170      1180      1190        
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
       1230      1240      1250      1260      1270      1280      

     1200      1210      1220      1230      1240      1250        
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
       1290      1300      1310      1320      1330      1340      

     1260      1270      1280      1290      1300      1310        
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
       1350      1360      1370      1380      1390      1400      

     1320      1330      1340      1350      1360      1370        
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
       1410      1420      1430      1440      1450      1460      

     1380      1390      1400      1410      1420      1430        
pF1KE2 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
       1470      1480      1490      1500      1510      1520      

     1440      1450      1460      1470      1480      1490        
pF1KE2 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
       1530      1540      1550      1560      1570      1580      

     1500      1510      1520      1530      1540      1550        
pF1KE2 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
       1590      1600      1610      1620      1630      1640      

     1560      1570      1580      1590      1600      1610        
pF1KE2 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
       1650      1660      1670      1680      1690      1700      

     1620      1630      1640      1650      1660      1670        
pF1KE2 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
       1710      1720      1730      1740      1750      1760      

     1680      1690      1700      1710      1720      1730        
pF1KE2 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
       1770      1780      1790      1800      1810      1820      

     1740      1750      1760      1770      1780      1790        
pF1KE2 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
       1830      1840      1850      1860      1870      1880      

     1800      1810      1820      1830      1840      1850        
pF1KE2 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
       1890      1900      1910      1920      1930      1940      

     1860      1870      1880      1890      1900      1910        
pF1KE2 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
       1950      1960      1970      1980      1990      2000      

     1920      1930      1940      1950      1960      1970        
pF1KE2 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
       2010      2020      2030      2040      2050      2060      

     1980      1990      2000      2010      2020      2030        
pF1KE2 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
       2070      2080      2090      2100      2110      2120      

     2040      2050      2060      2070      2080      2090        
pF1KE2 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
       2130      2140      2150      2160      2170      2180      

     2100      2110      2120      2130      2140      2150        
pF1KE2 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
       2190      2200      2210      2220      2230      2240      

     2160      2170      2180      2190      2200      2210        
pF1KE2 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
       2250      2260      2270      2280      2290      2300      

     2220      2230      2240      2250      2260      2270        
pF1KE2 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
       2310      2320      2330      2340      2350      2360      

     2280      2290      2300      2310      2320      2330        
pF1KE2 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
       2370      2380      2390      2400      2410      2420      

     2340      2350      2360      2370      2380      2390        
pF1KE2 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
       2430      2440      2450      2460      2470      2480      

     2400      2410      2420      2430      2440      2450        
pF1KE2 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
       2490      2500      2510      2520      2530      2540      

     2460      2470      2480      2490      2500      2510        
pF1KE2 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
       2550      2560      2570      2580      2590      2600      

     2520      2530      2540      2550      2560      2570        
pF1KE2 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
       2610      2620      2630      2640      2650      2660      

     2580      2590      2600      2610      2620      2630        
pF1KE2 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
       ::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
       2670      2680      2690      2700      2710      2720      

     2640      2650      2660      2670      2680      2690        
pF1KE2 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
       2730      2740      2750      2760      2770      2780      

     2700      2710      2720      2730      2740      2750        
pF1KE2 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
       2790      2800      2810      2820      2830      2840      

     2760      2770      2780      2790      2800      2810        
pF1KE2 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
       2850      2860      2870      2880      2890      2900      

     2820      2830      2840      2850      2860      2870        
pF1KE2 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
       2910      2920      2930      2940      2950      2960      

     2880      2890      2900      2910      2920      2930        
pF1KE2 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
       2970      2980      2990      3000      3010      3020      

     2940      2950      2960      2970      2980      2990        
pF1KE2 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
       3030      3040      3050      3060      3070      3080      

     3000      3010      3020      3030      3040      3050        
pF1KE2 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
       3090      3100      3110      3120      3130      3140      

     3060      3070      3080      3090      3100      3110        
pF1KE2 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
       3150      3160      3170      3180      3190      3200      

     3120  
pF1KE2 CPAN
       ::::
XP_005 CPAN
       3210

>>XP_016866340 (OMIM: 156225,607855,618138) laminin subu  (3212 aa)
 initn: 14750 init1: 14750 opt: 14830  Z-score: 7014.0  bits: 1312.7 E(91774):    0
Smith-Waterman score: 21163; 97.2% identity (97.2% similar) in 3154 aa overlap (57-3122:59-3212)

         30        40        50        60        70        80      
pF1KE2 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
                                     ::::::::::::::::::::::::::::::
XP_016 AVRLAHELRARGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
       30        40        50        60        70        80        

         90       100       110       120       130       140      
pF1KE2 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
       90       100       110       120       130       140        

        150       160       170       180       190       200      
pF1KE2 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
      150       160       170       180       190       200        

        210       220       230       240       250       260      
pF1KE2 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
      210       220       230       240       250       260        

        270       280       290       300       310       320      
pF1KE2 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
      270       280       290       300       310       320        

        330       340       350       360       370       380      
pF1KE2 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
      330       340       350       360       370       380        

        390       400       410       420       430       440      
pF1KE2 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
      390       400       410       420       430       440        

        450       460       470       480       490       500      
pF1KE2 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
      450       460       470       480       490       500        

        510       520       530       540       550       560      
pF1KE2 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
      510       520       530       540       550       560        

        570       580       590       600       610       620      
pF1KE2 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
      570       580       590       600       610       620        

        630       640       650       660       670       680      
pF1KE2 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
      630       640       650       660       670       680        

        690       700       710       720       730       740      
pF1KE2 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
      690       700       710       720       730       740        

        750       760       770       780       790       800      
pF1KE2 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
      750       760       770       780       790       800        

        810       820       830       840       850       860      
pF1KE2 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
      810       820       830       840       850       860        

        870       880       890       900       910       920      
pF1KE2 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
      870       880       890       900       910       920        

        930       940       950                                    
pF1KE2 SEVCHSQTGQCECRANVQGQRCDKCK----------------------------------
       ::::::::::::::::::::::::::                                  
XP_016 SEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCV
      930       940       950       960       970       980        

                                                                   
pF1KE2 ------------------------------------------------------AGTFGL
                                                             ::::::
XP_016 CKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGL
      990      1000      1010      1020      1030      1040        

      960       970       980       990      1000      1010        
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
     1050      1060      1070      1080      1090      1100        

     1020      1030      1040      1050      1060      1070        
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
     1110      1120      1130      1140      1150      1160        

     1080      1090      1100      1110      1120      1130        
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
     1170      1180      1190      1200      1210      1220        

     1140      1150      1160      1170      1180      1190        
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
     1230      1240      1250      1260      1270      1280        

     1200      1210      1220      1230      1240      1250        
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
     1290      1300      1310      1320      1330      1340        

     1260      1270      1280      1290      1300      1310        
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
     1350      1360      1370      1380      1390      1400        

     1320      1330      1340      1350      1360      1370        
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
     1410      1420      1430      1440      1450      1460        

     1380      1390      1400      1410      1420      1430        
pF1KE2 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
     1470      1480      1490      1500      1510      1520        

     1440      1450      1460      1470      1480      1490        
pF1KE2 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
     1530      1540      1550      1560      1570      1580        

     1500      1510      1520      1530      1540      1550        
pF1KE2 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
     1590      1600      1610      1620      1630      1640        

     1560      1570      1580      1590      1600      1610        
pF1KE2 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
     1650      1660      1670      1680      1690      1700        

     1620      1630      1640      1650      1660      1670        
pF1KE2 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
     1710      1720      1730      1740      1750      1760        

     1680      1690      1700      1710      1720      1730        
pF1KE2 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
     1770      1780      1790      1800      1810      1820        

     1740      1750      1760      1770      1780      1790        
pF1KE2 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
     1830      1840      1850      1860      1870      1880        

     1800      1810      1820      1830      1840      1850        
pF1KE2 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
     1890      1900      1910      1920      1930      1940        

     1860      1870      1880      1890      1900      1910        
pF1KE2 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
     1950      1960      1970      1980      1990      2000        

     1920      1930      1940      1950      1960      1970        
pF1KE2 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
     2010      2020      2030      2040      2050      2060        

     1980      1990      2000      2010      2020      2030        
pF1KE2 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
     2070      2080      2090      2100      2110      2120        

     2040      2050      2060      2070      2080      2090        
pF1KE2 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
     2130      2140      2150      2160      2170      2180        

     2100      2110      2120      2130      2140      2150        
pF1KE2 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
     2190      2200      2210      2220      2230      2240        

     2160      2170      2180      2190      2200      2210        
pF1KE2 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
     2250      2260      2270      2280      2290      2300        

     2220      2230      2240      2250      2260      2270        
pF1KE2 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
     2310      2320      2330      2340      2350      2360        

     2280      2290      2300      2310      2320      2330        
pF1KE2 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
     2370      2380      2390      2400      2410      2420        

     2340      2350      2360      2370      2380      2390        
pF1KE2 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
     2430      2440      2450      2460      2470      2480        

     2400      2410      2420      2430      2440      2450        
pF1KE2 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
     2490      2500      2510      2520      2530      2540        

     2460      2470      2480      2490      2500      2510        
pF1KE2 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
     2550      2560      2570      2580      2590      2600        

     2520      2530      2540      2550      2560      2570        
pF1KE2 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
     2610      2620      2630      2640      2650      2660        

     2580      2590      2600      2610      2620      2630        
pF1KE2 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
       ::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
     2670      2680      2690      2700      2710      2720        

     2640      2650      2660      2670      2680      2690        
pF1KE2 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
     2730      2740      2750      2760      2770      2780        

     2700      2710      2720      2730      2740      2750        
pF1KE2 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
     2790      2800      2810      2820      2830      2840        

     2760      2770      2780      2790      2800      2810        
pF1KE2 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
     2850      2860      2870      2880      2890      2900        

     2820      2830      2840      2850      2860      2870        
pF1KE2 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
     2910      2920      2930      2940      2950      2960        

     2880      2890      2900      2910      2920      2930        
pF1KE2 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
     2970      2980      2990      3000      3010      3020        

     2940      2950      2960      2970      2980      2990        
pF1KE2 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
     3030      3040      3050      3060      3070      3080        

     3000      3010      3020      3030      3040      3050        
pF1KE2 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
     3090      3100      3110      3120      3130      3140        

     3060      3070      3080      3090      3100      3110        
pF1KE2 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
     3150      3160      3170      3180      3190      3200        

     3120  
pF1KE2 CPAN
       ::::
XP_016 CPAN
     3210  

>>XP_011534122 (OMIM: 156225,607855,618138) laminin subu  (3208 aa)
 initn: 14009 init1: 7904 opt: 14805  Z-score: 7002.2  bits: 1310.5 E(91774):    0
Smith-Waterman score: 21138; 97.1% identity (97.1% similar) in 3154 aa overlap (57-3122:57-3208)

         30        40        50        60        70        80      
pF1KE2 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
                                     ::::::::::::::::::::::::::::::
XP_011 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
         30        40        50        60        70        80      

         90       100       110       120       130       140      
pF1KE2 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
         90       100       110       120       130       140      

        150       160       170       180       190       200      
pF1KE2 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
        150       160       170       180       190       200      

        210       220       230       240       250       260      
pF1KE2 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
        210       220       230       240       250       260      

        270       280       290       300       310       320      
pF1KE2 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
        270       280       290       300       310       320      

        330       340       350       360       370       380      
pF1KE2 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
        330       340       350       360       370       380      

        390       400       410       420       430       440      
pF1KE2 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
        390       400       410       420       430       440      

        450       460       470       480       490       500      
pF1KE2 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
        450       460       470       480       490       500      

        510       520       530       540       550       560      
pF1KE2 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
        510       520       530       540       550       560      

        570       580       590       600       610       620      
pF1KE2 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
        570       580       590       600       610       620      

        630       640       650       660       670       680      
pF1KE2 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
        630       640       650       660       670       680      

        690       700       710       720       730       740      
pF1KE2 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
        690       700       710       720       730       740      

        750       760       770       780       790       800      
pF1KE2 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
        750       760       770       780       790       800      

        810       820       830       840       850       860      
pF1KE2 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
        810       820       830       840       850       860      

        870       880       890       900       910       920      
pF1KE2 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
        870       880       890       900       910       920      

        930       940       950                                    
pF1KE2 SEVCHSQTGQCECRANVQGQRCDKCK----------------------------------
       ::::::::::::::::::::::::::                                  
XP_011 SEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCV
        930       940       950       960       970       980      

                                                                   
pF1KE2 ------------------------------------------------------AGTFGL
                                                             ::::::
XP_011 CKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGL
        990      1000      1010      1020      1030      1040      

      960       970       980       990      1000      1010        
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
       1050      1060      1070      1080      1090      1100      

     1020      1030      1040      1050      1060      1070        
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
       1110      1120      1130      1140      1150      1160      

     1080      1090      1100      1110      1120      1130        
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
       1170      1180      1190      1200      1210      1220      

     1140      1150      1160      1170      1180      1190        
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
       1230      1240      1250      1260      1270      1280      

     1200      1210      1220      1230      1240      1250        
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
       1290      1300      1310      1320      1330      1340      

     1260      1270      1280      1290      1300      1310        
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
       1350      1360      1370      1380      1390      1400      

     1320      1330      1340      1350      1360      1370        
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
       1410      1420      1430      1440      1450      1460      

     1380      1390      1400      1410      1420      1430        
pF1KE2 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
       1470      1480      1490      1500      1510      1520      

     1440      1450      1460      1470      1480      1490        
pF1KE2 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
       1530      1540      1550      1560      1570      1580      

     1500      1510      1520      1530      1540      1550        
pF1KE2 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
       1590      1600      1610      1620      1630      1640      

     1560      1570      1580      1590      1600      1610        
pF1KE2 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
       1650      1660      1670      1680      1690      1700      

     1620      1630      1640      1650      1660      1670        
pF1KE2 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
       1710      1720      1730      1740      1750      1760      

     1680      1690      1700      1710      1720      1730        
pF1KE2 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
       1770      1780      1790      1800      1810      1820      

     1740      1750      1760      1770      1780      1790        
pF1KE2 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
       1830      1840      1850      1860      1870      1880      

     1800      1810      1820      1830      1840      1850        
pF1KE2 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
       1890      1900      1910      1920      1930      1940      

     1860      1870      1880      1890      1900      1910        
pF1KE2 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
       1950      1960      1970      1980      1990      2000      

     1920      1930      1940      1950      1960      1970        
pF1KE2 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
       2010      2020      2030      2040      2050      2060      

     1980      1990      2000      2010      2020      2030        
pF1KE2 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
       2070      2080      2090      2100      2110      2120      

     2040      2050      2060      2070      2080      2090        
pF1KE2 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
       :::::::::::::::::::::::::::::::::::::::::::::::::::  :::::::
XP_011 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKN--IADADAT
       2130      2140      2150      2160      2170        2180    

     2100      2110      2120      2130      2140      2150        
pF1KE2 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
         2190      2200      2210      2220      2230      2240    

     2160      2170      2180      2190      2200      2210        
pF1KE2 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
         2250      2260      2270      2280      2290      2300    

     2220      2230      2240      2250      2260      2270        
pF1KE2 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
         2310      2320      2330      2340      2350      2360    

     2280      2290      2300      2310      2320      2330        
pF1KE2 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
         2370      2380      2390      2400      2410      2420    

     2340      2350      2360      2370      2380      2390        
pF1KE2 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
         2430      2440      2450      2460      2470      2480    

     2400      2410      2420      2430      2440      2450        
pF1KE2 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
         2490      2500      2510      2520      2530      2540    

     2460      2470      2480      2490      2500      2510        
pF1KE2 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
         2550      2560      2570      2580      2590      2600    

     2520      2530      2540      2550      2560      2570        
pF1KE2 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
         2610      2620      2630      2640      2650      2660    

     2580      2590      2600      2610      2620      2630        
pF1KE2 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
       ::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
         2670      2680      2690      2700      2710      2720    

     2640      2650      2660      2670      2680      2690        
pF1KE2 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
         2730      2740      2750      2760      2770      2780    

     2700      2710      2720      2730      2740      2750        
pF1KE2 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
         2790      2800      2810      2820      2830      2840    

     2760      2770      2780      2790      2800      2810        
pF1KE2 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
         2850      2860      2870      2880      2890      2900    

     2820      2830      2840      2850      2860      2870        
pF1KE2 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
         2910      2920      2930      2940      2950      2960    

     2880      2890      2900      2910      2920      2930        
pF1KE2 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
         2970      2980      2990      3000      3010      3020    

     2940      2950      2960      2970      2980      2990        
pF1KE2 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
         3030      3040      3050      3060      3070      3080    

     3000      3010      3020      3030      3040      3050        
pF1KE2 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
         3090      3100      3110      3120      3130      3140    

     3060      3070      3080      3090      3100      3110        
pF1KE2 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
         3150      3160      3170      3180      3190      3200    

     3120  
pF1KE2 CPAN
       ::::
XP_011 CPAN
           

>>XP_005267039 (OMIM: 156225,607855,618138) laminin subu  (3206 aa)
 initn: 14713 init1: 10439 opt: 14789  Z-score: 6994.6  bits: 1309.1 E(91774):    0
Smith-Waterman score: 21122; 97.1% identity (97.1% similar) in 3154 aa overlap (57-3122:57-3206)

         30        40        50        60        70        80      
pF1KE2 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
                                     ::::::::::::::::::::::::::::::
XP_005 QQRQSQAHQQRGLFPAVLNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRIC
         30        40        50        60        70        80      

         90       100       110       120       130       140      
pF1KE2 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANS
         90       100       110       120       130       140      

        150       160       170       180       190       200      
pF1KE2 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKI
        150       160       170       180       190       200      

        210       220       230       240       250       260      
pF1KE2 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREI
        210       220       230       240       250       260      

        270       280       290       300       310       320      
pF1KE2 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPIVTRRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFH
        270       280       290       300       310       320      

        330       340       350       360       370       380      
pF1KE2 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTA
        330       340       350       360       370       380      

        390       400       410       420       430       440      
pF1KE2 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKT
        390       400       410       420       430       440      

        450       460       470       480       490       500      
pF1KE2 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFN
        450       460       470       480       490       500      

        510       520       530       540       550       560      
pF1KE2 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDMSGWYLTDLPGRIRVAPQQDDLDSPQQ
        510       520       530       540       550       560      

        570       580       590       600       610       620      
pF1KE2 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISISNAEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMII
        570       580       590       600       610       620      

        630       640       650       660       670       680      
pF1KE2 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESFTIHGTHFPVRRKEFMTVLANLKRVLL
        630       640       650       660       670       680      

        690       700       710       720       730       740      
pF1KE2 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVN
        690       700       710       720       730       740      

        750       760       770       780       790       800      
pF1KE2 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP
        750       760       770       780       790       800      

        810       820       830       840       850       860      
pF1KE2 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQ
        810       820       830       840       850       860      

        870       880       890       900       910       920      
pF1KE2 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSF
        870       880       890       900       910       920      

        930       940       950                                    
pF1KE2 SEVCHSQTGQCECRANVQGQRCDKCK----------------------------------
       ::::::::::::::::::::::::::                                  
XP_005 SEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPEKRFCVLCDCDPVGSVSPQCDITGRCV
        930       940       950       960       970       980      

                                                                   
pF1KE2 ------------------------------------------------------AGTFGL
                                                             ::::::
XP_005 CKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQRWAIGSSSGCPRGAYRAPAPAGTFGL
        990      1000      1010      1020      1030      1040      

      960       970       980       990      1000      1010        
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
       1050      1060      1070      1080      1090      1100      

     1020      1030      1040      1050      1060      1070        
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
       1110      1120      1130      1140      1150      1160      

     1080      1090      1100      1110      1120      1130        
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
       1170      1180      1190      1200      1210      1220      

     1140      1150      1160      1170      1180      1190        
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
       1230      1240      1250      1260      1270      1280      

     1200      1210      1220      1230      1240      1250        
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
       1290      1300      1310      1320      1330      1340      

     1260      1270      1280      1290      1300      1310        
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
       1350      1360      1370      1380      1390      1400      

     1320      1330      1340      1350      1360      1370        
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPPADLIE
       1410      1420      1430      1440      1450      1460      

     1380      1390      1400      1410      1420      1430        
pF1KE2 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN
       1470      1480      1490      1500      1510      1520      

     1440      1450      1460      1470      1480      1490        
pF1KE2 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP
       1530      1540      1550      1560      1570      1580      

     1500      1510      1520      1530      1540      1550        
pF1KE2 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD
       1590      1600      1610      1620      1630      1640      

     1560      1570      1580      1590      1600      1610        
pF1KE2 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQE
       1650      1660      1670      1680      1690      1700      

     1620      1630      1640      1650      1660      1670        
pF1KE2 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSL
       1710      1720      1730      1740      1750      1760      

     1680      1690      1700      1710      1720      1730        
pF1KE2 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE
       1770      1780      1790      1800      1810      1820      

     1740      1750      1760      1770      1780      1790        
pF1KE2 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIR
       1830      1840      1850      1860      1870      1880      

     1800      1810      1820      1830      1840      1850        
pF1KE2 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVED
       1890      1900      1910      1920      1930      1940      

     1860      1870      1880      1890      1900      1910        
pF1KE2 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNIS
       1950      1960      1970      1980      1990      2000      

     1920      1930      1940      1950      1960      1970        
pF1KE2 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL
       2010      2020      2030      2040      2050      2060      

     1980      1990      2000      2010      2020      2030        
pF1KE2 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVK
       2070      2080      2090      2100      2110      2120      

     2040      2050      2060      2070      2080      2090        
pF1KE2 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADAT
       2130      2140      2150      2160      2170      2180      

     2100      2110      2120      2130      2140      2150        
pF1KE2 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTY
       2190      2200      2210      2220      2230      2240      

     2160      2170      2180      2190      2200      2210        
pF1KE2 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVE
       2250      2260      2270      2280      2290      2300      

     2220      2230      2240      2250      2260      2270        
pF1KE2 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDANAM
       2310      2320      2330      2340      2350      2360      

     2280      2290      2300      2310      2320      2330        
pF1KE2 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSPQVEDSE
       2370      2380      2390      2400      2410      2420      

     2340      2350      2360      2370      2380      2390        
pF1KE2 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTIQFDGEGYALVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHI
       2430      2440      2450      2460      2470      2480      

     2400      2410      2420      2430      2440      2450        
pF1KE2 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNF
       2490      2500      2510      2520      2530      2540      

     2460      2470      2480      2490      2500      2510        
pF1KE2 GLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
       :::::::::::::::::::::    :::::::::::::::::::::::::::::::::::
XP_005 GLDLKADDKIYFGGLPTLRNL----RPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVT
       2550      2560          2570      2580      2590      2600  

     2520      2530      2540      2550      2560      2570        
pF1KE2 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKR
           2610      2620      2630      2640      2650      2660  

     2580      2590      2600      2610      2620      2630        
pF1KE2 RQTGQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
       ::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQTGQAYYAILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQ
           2670      2680      2690      2700      2710      2720  

     2640      2650      2660      2670      2680      2690        
pF1KE2 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDENRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVPMDFAR
           2730      2740      2750      2760      2770      2780  

     2700      2710      2720      2730      2740      2750        
pF1KE2 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVSFKNADIGRCAHQKLREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPA
           2790      2800      2810      2820      2830      2840  

     2760      2770      2780      2790      2800      2810        
pF1KE2 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQL
           2850      2860      2870      2880      2890      2900  

     2820      2830      2840      2850      2860      2870        
pF1KE2 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADI
           2910      2920      2930      2940      2950      2960  

     2880      2890      2900      2910      2920      2930        
pF1KE2 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFANA
           2970      2980      2990      3000      3010      3020  

     2940      2950      2960      2970      2980      2990        
pF1KE2 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRGTYFDGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLM
           3030      3040      3050      3060      3070      3080  

     3000      3010      3020      3030      3040      3050        
pF1KE2 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTVDGNQVEAQSPNPASTSA
           3090      3100      3110      3120      3130      3140  

     3060      3070      3080      3090      3100      3110        
pF1KE2 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS
           3150      3160      3170      3180      3190      3200  

     3120  
pF1KE2 CPAN
       ::::
XP_005 CPAN
           

>>XP_016866342 (OMIM: 156225,607855,618138) laminin subu  (1916 aa)
 initn: 13354 init1: 7084 opt: 7333  Z-score: 3480.2  bits: 658.1 E(91774): 4.4e-187
Smith-Waterman score: 12963; 95.3% identity (95.4% similar) in 1904 aa overlap (1-1816:1-1904)

               10        20        30        40        50        60
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNED
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQDM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAVGG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEESF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIAAA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL
              850       860       870       880       890       900

              910       920       930       940       950          
pF1KE2 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCK--------
       ::::::::::::::::::::::::::::::::::::::::::::::::::::        
XP_016 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKPNMWRDPE
              910       920       930       940       950       960

                                                                   
pF1KE2 ------------------------------------------------------------
                                                                   
XP_016 KRFCVLCDCDPVGSVSPQCDITGRCVCKSGFVGKQCNLGRQVHQQEEQPRRAQRVLGSPQ
              970       980       990      1000      1010      1020

                                960       970       980       990  
pF1KE2 --------------------AGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVT
                           ::::::::::::::::::::::::::::::::::::::::
XP_016 RWAIGSSSGCPRGAYRAPAPAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVT
             1030      1040      1050      1060      1070      1080

           1000      1010      1020      1030      1040      1050  
pF1KE2 GKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS
             1090      1100      1110      1120      1130      1140

           1060      1070      1080      1090      1100      1110  
pF1KE2 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPG
             1150      1160      1170      1180      1190      1200

           1120      1130      1140      1150      1160      1170  
pF1KE2 TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT
             1210      1220      1230      1240      1250      1260

           1180      1190      1200      1210      1220      1230  
pF1KE2 TQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEP
             1270      1280      1290      1300      1310      1320

           1240      1250      1260      1270      1280      1290  
pF1KE2 FYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHMA
             1330      1340      1350      1360      1370      1380

           1300      1310      1320      1330      1340      1350  
pF1KE2 APLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQS
             1390      1400      1410      1420      1430      1440

           1360      1370      1380      1390      1400      1410  
pF1KE2 RISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGP
             1450      1460      1470      1480      1490      1500

           1420      1430      1440      1450      1460      1470  
pF1KE2 TLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACP
             1510      1520      1530      1540      1550      1560

           1480      1490      1500      1510      1520      1530  
pF1KE2 LISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPY
             1570      1580      1590      1600      1610      1620

           1540      1550      1560      1570      1580      1590  
pF1KE2 GSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQM
             1630      1640      1650      1660      1670      1680

           1600      1610      1620      1630      1640      1650  
pF1KE2 VMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLT
             1690      1700      1710      1720      1730      1740

           1660      1670      1680      1690      1700      1710  
pF1KE2 RATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RATKVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFER
             1750      1760      1770      1780      1790      1800

           1720      1730      1740      1750      1760      1770  
pF1KE2 NLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDL
             1810      1820      1830      1840      1850      1860

           1780      1790      1800      1810      1820      1830  
pF1KE2 REKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTL
       :::::::::::::::::::::::::::::::::::::::::::.                
XP_016 REKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEQLPAKVIKTNQSI    
             1870      1880      1890      1900      1910          

           1840      1850      1860      1870      1880      1890  
pF1KE2 KEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQ

>>NP_005550 (OMIM: 150320,615960) laminin subunit alpha-  (3075 aa)
 initn: 6677 init1: 2247 opt: 7179  Z-score: 3405.3  bits: 644.9 E(91774): 6.6e-183
Smith-Waterman score: 9933; 46.0% identity (72.0% similar) in 3134 aa overlap (6-3120:4-3071)

               10        20        30        40        50        60
pF1KE2 MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATCGE
            ::::.:::      : ::           .:::::::.::::::: :.:::::::
NP_005   MRGGVLLVLLLC-----VAAQ----------CRQRGLFPAILNLASNAHISTNATCGE
                 10                       20        30        40   

               70        80        90       100       110       120
pF1KE2 KGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAIDGKNTWWQSPSIKNGIE
       :::::.:::::::::.::::::::::. ::.:: .::::..:::: :.:::::::.:: :
NP_005 KGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNNWWQSPSIQNGRE
            50        60        70        80        90       100   

              130       140       150       160       170       180
pF1KE2 YHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLY
       ::.:::::::.::::.::::.::::.::::::::::::: . ..::::.::.:.:::. :
NP_005 YHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRY
           110       120       130       140       150       160   

              190       200       210       220       230       240
pF1KE2 NIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARY
       :: :: :::.:  ::::::::.::.. :::.:::: ::::::::::: ::.:::::::::
NP_005 NITPRRGPPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSPKLLEFTSARY
           170       180       190       200       210       220   

              250       260       270       280       290       300
pF1KE2 IRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVGGMCICYGHARACPLDP
       ::::.::::::::::: ..:..:.:.:::::::::::.::::::::::::::: .:: : 
NP_005 IRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDE
           230       240       250       260       270       280   

              310       320       330       340       350       360
pF1KE2 ATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVA
       .:.: .:.:::::::.::..::::.::.::: ::  . . :::::::.::..:::::.::
NP_005 TTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVA
           290       300       310       320       330       340   

              370       380       390       400       410       420
pF1KE2 RRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIG
       ... :::  :.. :::::::: ::: ::::::: ::..::. :::   .::.::.:::.:
NP_005 KQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVG
           350       360       370       380       390       400   

              430         440       450       460       470        
pF1KE2 SLNEVCVKDEKHA--RRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKN
       ::. ::.::. :.  . :  ::.: :: :. : .::::  ::  :: : .:.:. .:: .
NP_005 SLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSAS
           410       420       430       440       450       460   

      480       490       500       510       520       530        
pF1KE2 EDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYGKIQ
       ..:: :::.:::::::  :.::: ::.::.: : .::.:::: :::. :.:  :  :...
NP_005 DEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVN
           470       480       490       500       510       520   

      540       550       560       570       580       590        
pF1KE2 DMSGWYLTDLPGRIRVAPQQDDLDSPQQISISNAEARQALPHSYYWSAPAPYLGNKLPAV
       .:::: .::: .  ..  ::: : . .:.::.:. . : :  .:::.::  :::::: : 
NP_005 SMSGWLVTDLISPRKIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAF
           530       540       550       560       570       580   

      600       610       620       630       640       650        
pF1KE2 GGQLTFTISYDLEEEEEDTERVLQLMIILEGNDLSISTAQDEVYLHPSEEHTNVLLLKEE
       :: : .:.:::.  :  :.. . .  .:..:: :..::  . . :.: ::. ::. :  :
NP_005 GGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRLVPE
           590       600       610       620       630       640   

      660       670       680       690       700       710        
pF1KE2 SFTIHGTHFPVRRKEFMTVLANLKRVLLQITYSFGMDAIFRLSSVNLESAVSYPTDGSIA
       .:    ..  . : ..::::::. ..:.. .:. .  :..:: ::.:. : :   :  .:
NP_005 NFQDFHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVA
           650       660       670       680       690       700   

      720       730       740       750       760       770        
pF1KE2 AAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKD
       : :: :.:: ::::.:::::   . ::.: .:::::.::.: :::  :. : : :. :  
NP_005 ADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECN-VHGVCIACAH
           710       720       730       740       750        760  

      780       790       800       810       820       830        
pF1KE2 HTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVG
       .: : .:..:::::::::..::  :::::::::.: ::::::::::. .  ..:: :  :
NP_005 NTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPG
            770       780       790       800       810       820  

      840       850       860       870       880       890        
pF1KE2 YTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYC
       :.:  :::::.::.:.:.::: :: ::.:. :.: :  : :::..: :: :  .: : .:
NP_005 YSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC
            830       840       850       860       870       880  

      900       910       920       930       940       950        
pF1KE2 ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGL
       : ::::..:::: ::::. :.:.. :: : ::: .:: :.:. :: ::.::.:  : .::
NP_005 ERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGL
            890       900       910       920       930       940  

      960       970       980       990      1000      1010        
pF1KE2 QSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSH
       .:..:: ::::.  :: :  : . ::: : :::.::.:::::::.. .:.:.:: :.: :
NP_005 DSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPH
            950       960       970       980       990      1000  

     1020      1030      1040      1050      1060      1070        
pF1KE2 LGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ
         :.:::.::.:.:::.: : :: .:  . ::..  .::.::::: :::   .:.: ::.
NP_005 TQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGH
           1010      1020      1030      1040      1050      1060  

     1080      1090      1100      1110      1120      1130        
pF1KE2 CNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV
       :.:. ::.:  : .:: :. ..: :  ::: : ::.. .:. :   :.: ..:: : :: 
NP_005 CQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKE
           1070      1080      1090      1100      1110      1120  

     1140      1150      1160      1170      1180      1190        
pF1KE2 NVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLV
       :: : .:..:: : :.: : :::::: :.: : .  ::: .  .:: ::: ..: .: .:
NP_005 NVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVV
           1130      1140      1150      1160      1170      1180  

     1200      1210      1220      1230      1240      1250        
pF1KE2 DEALQHTTTKGIVFQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIY
       ...  . ::.:. .: :...     .:. .. :::::.::.::.: .::::::::::.. 
NP_005 SQSNLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVA
           1190      1200      1210      1220      1230      1240  

     1260      1270      1280      1290      1300      1310        
pF1KE2 FEAREETGFSTYNPQVIIRGGTPTHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDP
       : . . .: :...:::.:.::   . ..:     ::  :   ..:. : :. :::.  . 
NP_005 FYSLDGVGTSNFEPQVLIKGGR-IRKQVIYMDAPAPENGVRQEQEVAMRENFWKYF--NS
           1250      1260       1270      1280      1290           

     1320      1330      1340      1350      1360      1370        
pF1KE2 RVHRTVTREDFLDILYDIHYILIKATYGNFMRQSRISEISMEVAEQGRGTTMTPP----A
         .. ::::::...: ::.::::::.::. ..:::::.:::::   :: .    :    :
NP_005 VSEKPVTREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEV---GRKAEKLHPEEEVA
    1300      1310      1320      1330      1340         1350      

         1380      1390      1400       1410      1420      1430   
pF1KE2 DLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGG-RTPGPTLGTCVPCQCNGHSSLCDPET
       .:.:.: :: :  :.::. : ::..: .   :. : : : .. ::::.::.::. :::.:
NP_005 SLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNT
       1360      1370      1380      1390      1400      1410      

          1440      1450      1460      1470      1480      1490   
pF1KE2 SICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYR
       . : ::  .:::: :. :. :::: : :  .::  ::::  :   .:::.:: ::  :.:
NP_005 GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPH-SPPASFSPTCVLEGDHDFR
       1420      1430      1440      1450       1460      1470     

          1500      1510      1520      1530      1540      1550   
pF1KE2 CTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGAT
       : ::  ::::..::::. .: :.: .::::::.:.:.:.::.   :: ..: :.:: ::.
NP_005 CDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGAS
        1480      1490      1500      1510      1520      1530     

          1560      1570      1580      1590      1600      1610   
pF1KE2 GRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPLPAPYKMLYGLE
       : .:: :.  :     .:: : :::.:.::.:: .. . :.:.:::: .:.:: .: .::
NP_005 GLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLE
        1540      1550      1560      1570      1580      1590     

          1620      1630      1640      1650      1660      1670   
pF1KE2 NMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAERTNT
       : :. :.. :  .   . : ..   .:. .. : ..:  . :.. :. ..... .::   
NP_005 NTTKYLQESLLKENMQKDLGKI---KLEGVAEETDNLQKKLTRMLASTQKVNRATERIFK
        1600      1610         1620      1630      1640      1650  

          1680      1690      1700      1710         1720      1730
pF1KE2 RAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAF---ERNLEGLQKEIDQMIKELRR
       ....:.  :..:  .   . ::.  ::.::   :: :   . .:...:..  .... .. 
NP_005 ESQDLAIAIERLQMSITEIMEKTT-LNQTL---DEDFLLPNSTLQNMQQNGTSLLEIMQI
           1660      1670       1680         1690      1700        

             1740      1750      1760      1770      1780      1790
pF1KE2 KNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLL
       ...   .. :  :: ::: ::..... . .   : : ...   . :. ..:..  :  :.
NP_005 RDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALV
     1710      1720      1730      1740      1750      1760        

             1800      1810      1820      1830      1840      1850
pF1KE2 REATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEIN
       :::  :..:.:.:. . . :.  .  ::  :.  .    . . .:  ..: :   .: ..
NP_005 REAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQ
     1770      1780      1790      1800      1810      1820        

             1860      1870      1880      1890      1900      1910
pF1KE2 SIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGI
       . ....:: : ::   : ..  .:::: .....:. .. : .::.:::...  . :: . 
NP_005 DALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRAEDHAAEFQRLADVLYSG
     1830      1840      1850      1860      1870      1880        

             1920      1930      1940      1950      1960      1970
pF1KE2 LDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGC
       :.. .:.:.:::.:  .. ::.. :.:.:..:..:.  . :.. :. .    :  ..:. 
NP_005 LENIRNVSLNATSAAYVHYNIQSLIEESEELARDAHRTVTETSLLSES----LVSNGKAA
     1890      1900      1910      1920      1930          1940    

             1980      1990      2000      2010      2020      2030
pF1KE2 LQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDT
       .:.: :.:.:...:.  .     .:. :... .  .    .. :  :..:  : :::.  
NP_005 VQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGI
         1950      1960      1970      1980      1990      2000    

             2040      2050      2060      2070      2080      2090
pF1KE2 AAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNK
         :   .:. : .:...: ..: ... : :.: . . . ...  .. .:. ...: .   
NP_005 RDKGAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMAT
         2010      2020      2030      2040      2050      2060    

             2100      2110      2120      2130      2140      2150
pF1KE2 IIADADATVKNLEQEADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSIKVSVSS
       ..:     ::..: .:. :.:.:::.: ::.::..:.:::: ::.:::::: ::::.::.
NP_005 LLAGR--KVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSA
           2070      2080      2090      2100      2110      2120  

             2160      2170      2180      2190      2200      2210
pF1KE2 GGDCIRTYKPEIKKGSYNNIVVNVKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDV
         ::::.:.:.:.. .::....::::   :::::::::.   ::::.:::.:.:.::::.
NP_005 DRDCIRAYQPQISSTNYNTLTLNVKTQEPDNLLFYLGSSTASDFLAVEMRRGRVAFLWDL
           2130      2140      2150      2160      2170      2180  

             2220      2230      2240      2250      2260      2270
pF1KE2 GSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTI
       :::  :.:.::. :::. :. : ..: :  :..::. ... . :  : :. : ::   ..
NP_005 GSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKS--P-TKTSKSPGTANV
           2190      2200      2210      2220         2230         

             2280      2290      2300      2310      2320      2330
pF1KE2 LDVDANAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTV
       :::. ....::::: :..::. ::.:  : ::.::.....: :::::. :.:: :.::  
NP_005 LDVNNSTLMFVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWNYIEREGKCRGCFG
    2240      2250      2260      2270      2280      2290         

             2340      2350       2360      2370      2380         
pF1KE2 SPQVEDSEGTIQFDGEGYALVSRPIRWYP-NISTVMFKFRTFSSSALLMYLATRDLRDFM
       : : ::   ...::: ::..: . .   : ... ... : ::: ..::.::..   .::.
NP_005 SSQNEDP--SFHFDGSGYSVVEKSL---PATVTQIIMLFNTFSPNGLLLYLGSYGTKDFL
    2300        2310      2320         2330      2340      2350    

    2390      2400      2410      2420      2430      2440         
pF1KE2 SVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDI-DTNQEEN
       :.::  :..::  :::::  ...... .:.: : .....: .::. ....:  .:...:.
NP_005 SIELFRGRVKVMTDLGSGPITLLTDRRYNNGTWYKIAFQRNRKQGVLAVIDAYNTSNKET
         2360      2370      2380      2390      2400      2410    

     2450      2460      2470      2480      2490      2500        
pF1KE2 IATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNI
           . : .  :.    : :: ::::  : .    :  :. :.. ::.:..::::. ...
NP_005 KQGETPGASSDLNRLDKDPIYVGGLPRSRVV----RRGVTTKSFVGCIKNLEISRSTFDL
         2420      2430      2440          2450      2460      2470

     2510      2520      2530      2540      2550      2560        
pF1KE2 LSSPDYVGVTKGCSLENVYTVSFPKPGFVELSPVPIDVGTEINLSFSTKNESGIILLGSG
       :   .  :: ::: :: . .::: : :..:: :  ..  .:  ..:.: : ::::: . :
NP_005 LR--NSYGVRKGCLLEPIRSVSFLKGGYIELPPKSLSPESEWLVTFATTNSSGIILAALG
               2480      2490      2500      2510      2520        

     2570      2580      2590      2600       2610      2620       
pF1KE2 GTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTGART-MRKIVIRPEPNLFHDGREHSVH
       :  .  :  :...   .. ..:  : .:::.. :  : .:: ...   .   ::. ::. 
NP_005 GD-VEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTGTCSDGQAHSIS
     2530       2540      2550      2560      2570      2580       

      2630      2640        2650       2660      2670      2680    
pF1KE2 VERTRGIFTVQVDENRRYMQNL--TVE-QPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCI
       . :.: :.:::.:::    ..:   :: . :.:..:.::: :     : :     :.:::
NP_005 LVRNRRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGEGTSLLTMRRSFHGCI
      2590      2600      2610      2620      2630      2640       

         2690      2700      2710      2720       2730      2740   
pF1KE2 WNLVINSVPMDFARPVSFKNADIGRCAHQKLREDEDGAAPAEIV-IQPEPVPTPAFPTPT
        ::..:   .::   :. ...:.  :    : :    :  ::   . :::    :::   
NP_005 KNLIFNLELLDFNSAVGHEQVDLDTCW---LSERPKLAPDAEDSKLLPEP---RAFPEQ-
      2650      2660      2670         2680      2690         2700 

          2750      2760      2770      2780      2790      2800   
pF1KE2 PVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLF
              :....    . :..::::..:::. . :... :...:..:: .:: : :::..
NP_005 -------CVVDAALEYVPGAHQFGLTQNSHFILPFNQSAVRKKLSVELSIRTFASSGLIY
                    2710      2720      2730      2740      2750   

          2810      2820      2830      2840      2850      2860   
pF1KE2 YMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYV
       :::. :.::.:..::..:  .: .:::.: :..  :. ..::.:: .:    :..:.. :
NP_005 YMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSHPALLSDGKWHTVKTDYVKRKGFITV
          2760      2770      2780      2790      2800      2810   

          2870       2880      2890      2900      2910      2920  
pF1KE2 DGASNRTISP-KKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADL
       ::  .  ..    . .::: :..:.:::: .: .:.:: .:.:: .:. .. .     : 
NP_005 DGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQARKIGNITHSIPACIGDVTVNSKQLDK
          2820      2830      2840      2850      2860      2870   

           2930      2940      2950       2960      2970      2980 
pF1KE2 EQPTSSFHVGTCFANAQRGTYFDGTGFAKAVG-GFKVGLDLLVEFEFRTTTTTGVLLGIS
       ..:.:.: :. :.: ::.::::::.:.:  :  :.::  :. . .::::.. .:::::::
NP_005 DSPVSAFTVNRCYAVAQEGTYFDGSGYAALVKEGYKVQSDVNITLEFRTSSQNGVLLGIS
          2880      2890      2900      2910      2920      2930   

            2990      3000      3010      3020      3030      3040 
pF1KE2 SQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKHRIELTV
       . :.:..:.:..: :..:::.:::::.::.:.  .   ::::.:: . ::: :::: : :
NP_005 TAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPKTATVLCDGKWHTLQANKSKHRITLIV
          2940      2950      2960      2970      2980      2990   

            3050      3060      3070      3080      3090      3100 
pF1KE2 DGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPL
       ::: : :.::.  :::.:::.:..:::.:  .::  : ..  ::::.:.: : : . .  
NP_005 DGNAVGAESPHTQSTSVDTNNPIYVGGYPAGVKQKCLRSQTSFRGCLRKLALIK-SPQVQ
          3000      3010      3020      3030      3040       3050  

            3110      3120    
pF1KE2 EVNFAKALELRGVQPVSCPAN  
         .:..:.::.::   :::    
NP_005 SFDFSRAFELHGVFLHSCPGTES
           3060      3070     

>>XP_011524284 (OMIM: 226650,226700,245660,600805) lamin  (3243 aa)
 initn: 2076 init1: 743 opt: 1426  Z-score: 691.4  bits: 142.8 E(91774): 9.6e-32
Smith-Waterman score: 3420; 26.7% identity (51.6% similar) in 3393 aa overlap (29-3039:37-3165)

                 10        20        30        40        50        
pF1KE2   MPGAAGVLLLLLLSGGLGGVQAQRPQQQRQSQAHQQRGLFPAVLNLASNALITTNATC
                                     :.  :    .: :. .:::  : : ..:::
XP_011 PRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATC
         10        20        30        40        50        60      

       60               70            80        90       100       
pF1KE2 GEKGP-------EMYCKLV--EHVPG--QPVRNPQCRICNQNSSNPNQRHPITNAIDGKN
       ::.::       :.:::::    .::  . ...  :  ::  : .: . ::.::::::..
XP_011 GERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCN--SEDPRKAHPVTNAIDGSE
         70        80        90       100         110       120    

       110       120       130       140       150        160      
pF1KE2 TWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPW
        ::::: ...: .:. :..:::: :.:..::...: ::::::  :.::::.:    :.::
XP_011 RWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPW
          130       140       150       160       170       180    

        170       180       190       200       210       220      
pF1KE2 QYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSAD
       :: : . ..::  ..   : .  . ..::.:.:.. ::.: ::::::. .:::::::.: 
XP_011 QYFAHSKVDCLKEFG---REANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAK
          190          200       210       220       230       240 

          230       240       250       260       270       280    
pF1KE2 DP--SPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDISVG
       .   :  : :::.:  ::::: :  :: . :.  :..::      ::::::::.::::.:
XP_011 NFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDP-----TVTRRYYYSIKDISIG
             250       260       270       280            290      

          290       300       310       320       330       340    
pF1KE2 GMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEAC
       :.:.: :::..: ..   .  ::::.:.:::..::.:: :..:. :: ...  . :::::
XP_011 GQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEAC
        300       310       320       330       340       350      

          350       360       370       380       390       400    
pF1KE2 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVS
       ::::.: .:::: .: :.. ::: .: : :::::::: .::::.::: :. :..:: :: 
XP_011 NCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP
        360       370       380       390       400       410      

          410                                   420                
pF1KE2 PNYPRPCQPCHCDP----------------------------IGSLN-EVCVK-------
        . :  : :: :::                            ::  :   :..       
XP_011 VDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVS
        420       430       440       450       460       470      

                430                440       450       460         
pF1KE2 ----------DEKHAR---RGLAP------GSCHCKTGFGGVSCDRCARGYTGYPDCKAC
                 : :      .:. :      : : :. :  :  :: :  :. ..: :.::
XP_011 TPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQAC
        480       490       500       510       520       530      

     470                           480                             
pF1KE2 NCSGLGS--------------------KNEDPCF--------------------------
        ::.:::                    .  : :.                          
XP_011 WCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNL
        540       550       560       570       580       590      

           490       500       510                                 
pF1KE2 GPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDEC-------------------------
       : : :: .:::  :::::  ..::...: .::.::                         
XP_011 GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKS
        600       610       620       630       640       650      

                                            520       530          
pF1KE2 --------------------------------------FCSGVSNRCQSSYWTYGKI--Q
                                             .::: :. ::    . ::.  .
XP_011 HVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQR
        660       670       680       690       700       710      

      540                    550                          560      
pF1KE2 DMSGWYLTDL------------P-GR-IRVA------PQ------------QDDLDSPQQ
         ...:. ::            : :: .: .      :.            :.:.    .
XP_011 PENNYYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLN
        720       730       740       750       760       770      

        570                   580                 590              
pF1KE2 ISISNAEA-----RQALP-------H-SYY--W-------SAPAPYLGNKLPAV------
       .. :..       : . :       : . :  :       :    .: .: ::       
XP_011 VGKSSGSLFRVILRYVNPGTEAVSGHITIYPSWGKARAAQSKEIIFLPSKEPAFVTVPGN
        780       790       800       810       820       830      

      600       610       620             630       640       650  
pF1KE2 GGQLTFTISYDLEEEEEDTERVLQLMIIL------EGNDLSISTAQDEVYLHPSEEHT--
       :    :.:.  .      .: ::  ...:      :.. :.. ...  .:  : .:..  
XP_011 GFADPFSITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQEKSVW
        840       850       860       870       880       890      

                              660       670          680       690 
pF1KE2 --NVLLLKE--------------ESFTIHGTHFPVRRKE---FMTVLANLKRVLLQITYS
         . :: ..              . : . :   ::  ..      :...:.   ...   
XP_011 GRSCLLYQHLPVTRFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLR
        900       910       920       930       940       950      

             700                710        720       730       740 
pF1KE2 FGMDAIFRLSSV---NLESA------VSYPTDGSI-AAAVEVCQCPPGYTGSSCESCWPR
       . .  . .   :   . :.:      :.  ..::. :. :.. .:  .:.   :.:    
XP_011 LRIPQVGHYVVVVEYSTEAAQLFVVDVNVKSSGSVLAGQVNIYSC--NYS-VLCRSAVID
        960       970       980       990      1000         1010   

              750        760             770       780       790   
pF1KE2 H-RRVNGTIFGGICEP-CQCFGHA------ESCDDVTGECLNCKDHTGGPYCDKCLPGFY
       :  :.  ...  . .   :  ::       . :  .  : .. .      .:      : 
XP_011 HMSRI--AMYELLADADIQLKGHMARFLLHQVCI-IPIEEFSAEYVRPQVHCIASYGRFV
            1020      1030      1040       1050      1060      1070

           800         810       820       830        840       850
pF1KE2 GEPTKGTS--EDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCP-VGYTGPRCERCAEG
       .. .  .:  ..  : :  :.. :.   :  :: .. .   :  : :   .:. .   .:
XP_011 NQSATCVSLAHETPPTALILDVLSG--RPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRG
             1080      1090        1100      1110      1120        

                 860       870          880       890       900    
pF1KE2 ---YFGQPSVPGGSCQPCQCNDNLDFSIPGS---CDSLSGSCLICKPGTTGRYCELCADG
          ..:.        :  . .   . :. :.     :. .:  .: : . :   .. :.:
XP_011 RVPHLGRYVFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHAS--FC-PHVLGCRDQVIAEG
     1130      1140      1150      1160        1170       1180     

           910       920                     930             940   
pF1KE2 YFG-DAVDAKNCQPCRCNAGGSFS--------------EVCHSQTGQ------CECRAN-
        .  :  . .     .   : :.               .. :... .       .:  : 
XP_011 QIEFDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNS
        1190      1200      1210      1220      1230      1240     

              950        960         970       980        990      
pF1KE2 --VQGQRCDK-CKAGTFGLQS--ARGCVPCNCNSFGSKSFDCE-ESGQCWCQPGVTGKKC
         .. :  .. :: .. .: .   .: .::.:.  :. .  :  :.::: :::.: :..:
XP_011 FYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQC
        1250      1260      1270      1280      1290      1300     

       1000      1010      1020      1030      1040      1050      
pF1KE2 DRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTG
        ::: :...: .  :  : :..    :.  ::.: ::: :.  .:  :  ....    .:
XP_011 TRCATGHYGFPR--CKPCSCGR--RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAG
        1310        1320        1330      1340      1350      1360 

       1060      1070         1080      1090      1100      1110   
pF1KE2 CKACNCSTVGSLDF---QCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGT
       :..::::  :...    .:. ..::: :.:...: .: .:. : . .:.:  :.:   ::
XP_011 CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGT
            1370      1380      1390      1400      1410      1420 

          1120      1130      1140      1150      1160      1170   
pF1KE2 DATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTT
       .  .::           :: : :: :::: .:. :: :.: ::  :  ::.::.:::...
XP_011 EPGVCDP---------GTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNN
                     1430      1440      1450      1460      1470  

          1180      1190      1200       1210      1220      1230  
pF1KE2 QCSEAKGLIRTWVTLKAEQTILPLVDEA-LQHTTTKGIVFQHPEIVAHMDLMREDLHLEP
       ::  ..     .: . . .  :  .:.. .  . . :       .:: .. .   .:   
XP_011 QCHSSHKRRTKFVDMLGWH--LETADRVDIPVSFNPG----SNSMVADLQELPATIHSAS
           1480      1490        1500          1510      1520      

           1240      1250       1260      1270      1280      1290 
pF1KE2 FYWKLPEQFEGKKLMAYGGKLKY-AIYFEAREETGFSTYNPQVIIRGGTPTHARIIVRHM
         :  : .. : :. .::: : : :  :    .  .   .:.: . :    :  :: .. 
XP_011 --WVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTG---QHMSIIYEET
         1530      1540      1550      1560      1570         1580 

            1300      1310      1320      1330      1340      1350 
pF1KE2 AAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTVTREDFLDILYDIHYILIKATYGNFMRQ
        .:   .: . .....: .... ..    .  :.::... .:  .  . :.. : .  ..
XP_011 NTPRPDRLHHGRVHVVEGNFRHASS----RAPVSREELMTVLSRLADVRIQGLYFTETQR
            1590      1600          1610      1620      1630       

            1360       1370      1380      1390      1400      1410
pF1KE2 SRISEISMEVA-EQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTP
         .::...: : . : :      :  .: : :: .:.: ::..: ::.::  .. :  : 
XP_011 LTLSEVGLEEASDTGSGRI----ALAVEICACPPAYAGDSCQGCSPGYYR--DHKGLYT-
      1640      1650          1660      1670      1680        1690 

             1420      1430      1440      1450      1460      1470
pF1KE2 GPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCA
           : ::::.:::::. :.  ..:: ::::.:::. ::::  ::::  ... ..:. : 
XP_011 ----GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACP
                 1700      1710      1720      1730        1740    

             1480      1490      1500      1510      1520      1530
pF1KE2 CPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECD
       ::    .:.:. .::..:  : ::. :  :: :  :::::::: :.: . ::::: : :.
XP_011 CP---HTNSFATGCVVNG-GDVRCS-CKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCN
            1750       1760       1770      1780      1790         

             1540         1550      1560      1570      1580       
pF1KE2 PYGSLPVPCDPVTGFCTC---RPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLA
         :.:   : :.:: :     . .. ...:: :               : :.  ::.:::
XP_011 SNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC---------------DSCVMTLLNDLA
    1800       1810      1820      1830                     1840   

       1590      1600      1610      1620          1630      1640  
pF1KE2 RL-EQMVMSINLTGPLPAPYKMLYGLENMTQELK----HLLSPQRAPERLIQLAEGNLNT
        . ::. .  .    : :   .:  ...:  . :    .::. . :     .  :: :. 
XP_011 TMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEG-LER
          1850      1860      1870      1880      1890       1900  

              1650      1660       1670      1680      1690        
pF1KE2 LVTEMN---ELLTRATKVTADGEQT-GQDAERTNTRAKSLGEFIKELARDAEAVNEKAIK
        .:..:   : : . ..:..   :: .....:..  :: :   ::.. :... . .   .
XP_011 ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLK---Q
           1910      1920      1930      1940      1950            

     1700      1710      1720      1730      1740      1750        
pF1KE2 LNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLF
       .. : :  ...   ..     : ..:..::: .:.  . . :: .   .. ::....   
XP_011 ISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQ
    1960      1970      1980      1990      2000      2010         

     1760      1770      1780      1790      1800      1810        
pF1KE2 GESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKK
          .:::. . ...:..: .:. :..:    :.::. . ..:: :   :.. . :.... 
XP_011 KTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQV
    2020      2030      2040      2050      2060      2070         

     1820      1830      1840      1850      1860      1870        
pF1KE2 EAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLS
       . ..: . .. . :  ... : ..:   . ...     : . ..:    .::.::. .::
XP_011 KEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELS
    2080      2090      2100      2110      2120      2130         

     1880      1890      1900      1910        1920      1930      
pF1KE2 QEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKN--ISFNATAAFKAYSNIKDYID
       .     .:.:   .::.:: .:.. .  :. :  .:..  .   :. :  :: :: . : 
XP_011 RSAGKTSLVE---EAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIK
    2140         2150      2160      2170      2180      2190      

       1940      1950      1960      1970      1980      1990      
pF1KE2 EAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLN
        :: .:..: . .. :  : :  .  : . ::   ..: ..:::::   . .:.    .:
XP_011 AAEDAANRAASASESA--LQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQ----VN
       2200      2210        2220      2230      2240          2250

       2000      2010      2020      2030      2040      2050      
pF1KE2 GLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQIT
        : ...        :: : ...   .:  . :  . ... ...  .:: :.:. : . . 
XP_011 KLTNKLP-------DLWRKIESINQQLLPLGN-ISDNMDRIRELIQQARDAASKVAVPMR
                    2260      2270       2280      2290      2300  

       2060      2070      2080      2090      2100      2110      
pF1KE2 ELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLIDKLKPI
            ..:             :... :. :.  . .    .    :..  .:        
XP_011 -----FNG-------------KSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR--------
                             2310      2320      2330              

       2120      2130      2140      2150       2160      2170     
pF1KE2 KELEDNLKKNISEIKELINQARKQANSIKVSVSSGG-DCIRTYKPEIKKGSYNNIVVN--
          :..  .:.  .  : :.  .. . : ..: .:   :. .   .  . . ..:...  
XP_011 ---ENGGTENMF-VMYLGNKDASR-DYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSE
          2340       2350       2360      2370      2380      2390 

          2180      2190      2200      2210      2220      2230   
pF1KE2 VKTAVADNLLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIV
       .: :: : . :     .. .:  ... :: .:         .. : :            :
XP_011 TKEAVMDRVKFQ----RIYQFARLNYTKGATS---------SKPETPG-----------V
            2400          2410               2420                  

          2240      2250      2260      2270       2280      2290  
pF1KE2 ASRTGRNGTISVRALDGPKASIVPSTHHSTSPPGYTILDVDA-NAMLFVGGLTGKLKKAD
        .  :::..                          :.:..:  :....:::    .:  .
XP_011 YDMDGRNSN--------------------------TLLNLDPENVVFYVGGYPPDFKLPS
      2430                                2440      2450      2460 

           2300      2310      2320      2330         2340         
pF1KE2 AVRVITFTGCMGETYFDNKPIGLWNFREKEGDCKGCTVSP---QVEDSEGTIQFDGEGYA
        .    . ::.    .... ..:.::. :  . .   : :   . :.:. .  :.: :::
XP_011 RLSFPPYKGCIELDDLNENVLSLYNFK-KTFNLNTTEVEPCRRRKEESDKNY-FEGTGYA
            2470      2480       2490      2500      2510          

    2350      2360      2370      2380      2390      2400         
pF1KE2 LVSRPIRWYPNISTVMFKFRTFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGSGMA
        :  : . .  : :    ..:  . .::..  . :   :.:... ::.. : : :.: . 
XP_011 RV--PTQPHAPIPTFGQTIQTTVDRGLLFFAENGD--RFISLNIEDGKLMVRYKLNSELP
    2520        2530      2540      2550        2560      2570     

    2410       2420        2430      2440      2450      2460      
pF1KE2 SVVSNQNH-NDGKWKSFTLS--RIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADD
       .  .  .  :.:. .:. ..  ..::.  :. ::...       :  .:. : ..     
XP_011 KERGVGDAINNGRDHSIQIKIGKLQKRMWIN-VDVQN-------TIIDGEVFDFST----
        2580      2590      2600       2610             2620       

       2470      2480      2490      2500      2510      2520      
pF1KE2 KIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLEN-
         :.::.:    .... : ...   . ::.:..   .   ...   : ::::: :: .  
XP_011 -YYLGGIP----IAIRERFNISTPAFRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDWK
           2630          2640      2650         2660      2670     

         2530         2540      2550      2560      2570      2580 
pF1KE2 -VYTVSFPKPG---FVELSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQT
        : ..:: . :   :..:.  : :   . ...:.: . :::.:              .::
XP_011 LVRSASFSRGGQLSFTDLGLPPTD-HLQASFGFQTFQPSGILL-------------DHQT
        2680      2690       2700      2710                   2720 

            2590      2600      2610      2620      2630      2640 
pF1KE2 GQAYYVILLNRGRLEVHLSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDE
             . :. : .:.  : ..  . :      :. . ::  : : :    . . . .:.
XP_011 WTRNLQVTLEDGYIELSTSDSGGPIFK-----SPQTYMDGLLHYVSVISDNSGLRLLIDD
            2730      2740           2750      2760      2770      

                2650      2660      2670      2680      2690       
pF1KE2 ----NRRYMQNLTVEQPIEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSV---P-
           : . .....  .    ..: .::.              ::::: :. .. .   : 
XP_011 QLLRNSKRLKHISSSR----QSLRLGGSN-------------FEGCISNVFVQRLSLSPE
       2780      2790          2800                   2810         

           2700      2710                2720      2730      2740  
pF1KE2 -MDFARPVSFKNADIGRCAHQK----------LREDEDGAAPAEIVIQPEPVPTPAFPTP
        .:..     .....: :. .:           : ..  .   . ..:  :: .:     
XP_011 VLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPR----
    2820      2830      2840      2850      2860      2870         

           2750      2760      2770      2780      2790      2800  
pF1KE2 TPVLTHGPCAAESEPALLIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLL
       .  . .  :.   .     :. :::   .::. . . .  .: :  . ....: .  ::.
XP_011 SVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLV
        2880      2890      2900      2910      2920      2930     

           2810      2820      2830      2840        2850      2860
pF1KE2 FYMARINHADFATVQLRNGLPYFSYDLGSGDTHTMIPTK--INDGQWHKIKIMRSKQEGI
       :. .  :  .: .. : .:   :.  ::.   .  : .:   :::.:: . . .. ..: 
XP_011 FHTGTKN--SFMALYLSKGRLVFA--LGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGR
        2940        2950        2960      2970      2980      2990 

             2870      2880      2890      2900      2910      2920
pF1KE2 LYVDGASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPA
       : :::   :  :    . ... . .:.:. : .   . . : : :. ::..:...   : 
XP_011 LVVDGLRAREGSLPGNSTISIRAPVYLGS-PPSGKPKSL-P-TNSFVGCLKNFQLDSKP-
            3000      3010      3020        3030       3040        

             2930       2940      2950        2960      2970       
pF1KE2 DLEQPTSSFHVGTCFANA-QRGTYFDGTGFAKAVGGFKV--GLDLLVEFEFRTTTTTGVL
        :  :.::: :..:...  ..: ::.  : ...: . .:  : .. . : .:  . ::.:
XP_011 -LYTPSSSFGVSSCLGGPLEKGIYFSEEG-GHVVLAHSVLLGPEFKLVFSIRPRSLTGIL
       3050      3060      3070       3080      3090      3100     

      2980      2990      3000      3010       3020      3030      
pF1KE2 LGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGVPGH-LCDGQWHKVTANKIKHR
       . :.::    . . .   :.   .:.:::   ..  . .: . :::::::.:...  .: 
XP_011 IHIGSQPGKHLCVYLEAGKVTASMDSGAG---GTSTSVTPKQSLCDGQWHSVAVTIKQHI
        3110      3120      3130         3140      3150      3160  

       3040      3050      3060      3070      3080      3090      
pF1KE2 IELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKG
       ..:                                                         
XP_011 LHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIP
           3170      3180      3190      3200      3210      3220  




3122 residues in 1 query   sequences
64092750 residues in 91774 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Jul 16 15:51:41 2019 done: Tue Jul 16 15:51:44 2019
 Total Scan time: 13.940 Total Display time:  2.420

Function used was FASTA [36.3.4 Apr, 2011]
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