Result of FASTA (omim) for
pF1KB5946
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5946, 495 aa
1>>>pF1KB5946 495 - 495 aa - 495 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8143+/-0.000393; mu= 11.5878+/- 0.024
mean_var=123.8499+/-26.514, 0's: 0 Z-trim(114.8): 420 B-trim: 0 in 0/50
Lambda= 0.115246
statistics sampled from 25349 (25780) to 25349 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.281), width: 16
Scan time: 4.490
The best scores are: opt bits E(91774)
NP_003813 (OMIM: 604453) nuclear receptor subfamil ( 495) 3315 562.8 8.7e-160
XP_011507682 (OMIM: 604453) nuclear receptor subfa ( 501) 3187 541.5 2.2e-153
XP_011507686 (OMIM: 604453) nuclear receptor subfa ( 501) 3187 541.5 2.2e-153
XP_016856393 (OMIM: 604453) nuclear receptor subfa ( 501) 3187 541.5 2.2e-153
XP_011507683 (OMIM: 604453) nuclear receptor subfa ( 501) 3187 541.5 2.2e-153
NP_995582 (OMIM: 604453) nuclear receptor subfamil ( 541) 3187 541.5 2.4e-153
NP_001263393 (OMIM: 604453) nuclear receptor subfa ( 469) 3149 535.2 1.7e-151
XP_005245119 (OMIM: 604453) nuclear receptor subfa ( 469) 3149 535.2 1.7e-151
XP_011507684 (OMIM: 604453) nuclear receptor subfa ( 469) 3149 535.2 1.7e-151
NP_004950 (OMIM: 184757,612964,612965,613957,61748 ( 461) 1900 327.5 5.4e-89
NP_775291 (OMIM: 600542,612237) nuclear receptor s ( 443) 416 80.7 9.9e-15
NP_008845 (OMIM: 601972,618357) nuclear receptor R ( 459) 415 80.6 1.1e-14
NP_001351952 (OMIM: 601972,618357) nuclear recepto ( 470) 415 80.6 1.2e-14
XP_016859709 (OMIM: 168600,601828) nuclear recepto ( 573) 414 80.5 1.5e-14
XP_006712616 (OMIM: 168600,601828) nuclear recepto ( 584) 414 80.5 1.6e-14
NP_008912 (OMIM: 600542,612237) nuclear receptor s ( 626) 413 80.4 1.8e-14
XP_016870651 (OMIM: 600542,612237) nuclear recepto ( 626) 413 80.4 1.8e-14
NP_775292 (OMIM: 600542,612237) nuclear receptor s ( 637) 413 80.4 1.9e-14
XP_005251974 (OMIM: 602778) nuclear receptor subfa ( 479) 407 79.3 3e-14
NP_775265 (OMIM: 168600,601828) nuclear receptor s ( 535) 404 78.8 4.6e-14
NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261) 399 77.8 4.7e-14
NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261) 399 77.8 4.7e-14
XP_011509548 (OMIM: 168600,601828) nuclear recepto ( 564) 404 78.8 4.8e-14
NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281) 399 77.8 4.9e-14
XP_016859708 (OMIM: 168600,601828) nuclear recepto ( 598) 404 78.8 5e-14
NP_006177 (OMIM: 168600,601828) nuclear receptor s ( 598) 404 78.8 5e-14
XP_005246678 (OMIM: 168600,601828) nuclear recepto ( 609) 404 78.8 5.1e-14
XP_005251975 (OMIM: 602778) nuclear receptor subfa ( 438) 401 78.2 5.6e-14
NP_001480 (OMIM: 602778) nuclear receptor subfamil ( 475) 401 78.3 5.9e-14
XP_016865286 (OMIM: 132890,615722) COUP transcript ( 273) 397 77.4 6.1e-14
NP_201591 (OMIM: 602778) nuclear receptor subfamil ( 480) 400 78.1 6.7e-14
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 397 77.5 7.6e-14
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 397 77.6 8.8e-14
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 397 77.6 9.2e-14
XP_024309743 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
NP_001230438 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
NP_001337054 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
XP_016856128 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
XP_016856127 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
NP_996318 (OMIM: 602969) estrogen-related receptor ( 435) 396 77.4 9.8e-14
XP_024309748 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
XP_016856130 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
NP_001230441 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
NP_996317 (OMIM: 602969) estrogen-related receptor ( 435) 396 77.4 9.8e-14
NP_001230440 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
XP_024309747 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
NP_001337052 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
XP_016856133 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
NP_001230444 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
XP_016856134 (OMIM: 602969) estrogen-related recep ( 435) 396 77.4 9.8e-14
>>NP_003813 (OMIM: 604453) nuclear receptor subfamily 5 (495 aa)
initn: 3315 init1: 3315 opt: 3315 Z-score: 2990.3 bits: 562.8 E(91774): 8.7e-160
Smith-Waterman score: 3315; 100.0% identity (100.0% similar) in 495 aa overlap (1-495:1-495)
10 20 30 40 50 60
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV
430 440 450 460 470 480
490
pF1KB5 PYNNLLIEMLHAKRA
:::::::::::::::
NP_003 PYNNLLIEMLHAKRA
490
>>XP_011507682 (OMIM: 604453) nuclear receptor subfamily (501 aa)
initn: 3180 init1: 3180 opt: 3187 Z-score: 2875.2 bits: 541.5 E(91774): 2.2e-153
Smith-Waterman score: 3187; 96.8% identity (98.4% similar) in 493 aa overlap (3-495:15-501)
10 20 30 40
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVS
:... :.. :... :::::::::::::::::::::::::::
XP_011 MLPKVETEALGLARSHGEQGQMPENMQ------VSQFKMVNYSYDEDLEELCPVCGDKVS
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 GYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 AVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 NIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 DPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 KHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQ
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 VVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFL
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB5 VLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAE
420 430 440 450 460 470
470 480 490
pF1KB5 EYLYYKHLNGDVPYNNLLIEMLHAKRA
:::::::::::::::::::::::::::
XP_011 EYLYYKHLNGDVPYNNLLIEMLHAKRA
480 490 500
>>XP_011507686 (OMIM: 604453) nuclear receptor subfamily (501 aa)
initn: 3180 init1: 3180 opt: 3187 Z-score: 2875.2 bits: 541.5 E(91774): 2.2e-153
Smith-Waterman score: 3187; 96.8% identity (98.4% similar) in 493 aa overlap (3-495:15-501)
10 20 30 40
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVS
:... :.. :... :::::::::::::::::::::::::::
XP_011 MLPKVETEALGLARSHGEQGQMPENMQ------VSQFKMVNYSYDEDLEELCPVCGDKVS
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 GYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 AVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 NIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 DPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 KHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQ
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 VVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFL
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB5 VLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAE
420 430 440 450 460 470
470 480 490
pF1KB5 EYLYYKHLNGDVPYNNLLIEMLHAKRA
:::::::::::::::::::::::::::
XP_011 EYLYYKHLNGDVPYNNLLIEMLHAKRA
480 490 500
>>XP_016856393 (OMIM: 604453) nuclear receptor subfamily (501 aa)
initn: 3180 init1: 3180 opt: 3187 Z-score: 2875.2 bits: 541.5 E(91774): 2.2e-153
Smith-Waterman score: 3187; 96.8% identity (98.4% similar) in 493 aa overlap (3-495:15-501)
10 20 30 40
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVS
:... :.. :... :::::::::::::::::::::::::::
XP_016 MLPKVETEALGLARSHGEQGQMPENMQ------VSQFKMVNYSYDEDLEELCPVCGDKVS
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 GYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 AVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 NIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 DPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 KHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQ
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 VVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFL
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB5 VLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAE
420 430 440 450 460 470
470 480 490
pF1KB5 EYLYYKHLNGDVPYNNLLIEMLHAKRA
:::::::::::::::::::::::::::
XP_016 EYLYYKHLNGDVPYNNLLIEMLHAKRA
480 490 500
>>XP_011507683 (OMIM: 604453) nuclear receptor subfamily (501 aa)
initn: 3180 init1: 3180 opt: 3187 Z-score: 2875.2 bits: 541.5 E(91774): 2.2e-153
Smith-Waterman score: 3187; 96.8% identity (98.4% similar) in 493 aa overlap (3-495:15-501)
10 20 30 40
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVS
:... :.. :... :::::::::::::::::::::::::::
XP_011 MLPKVETEALGLARSHGEQGQMPENMQ------VSQFKMVNYSYDEDLEELCPVCGDKVS
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 GYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 AVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 NIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 DPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 KHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQ
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB5 VVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFL
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB5 VLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAE
420 430 440 450 460 470
470 480 490
pF1KB5 EYLYYKHLNGDVPYNNLLIEMLHAKRA
:::::::::::::::::::::::::::
XP_011 EYLYYKHLNGDVPYNNLLIEMLHAKRA
480 490 500
>>NP_995582 (OMIM: 604453) nuclear receptor subfamily 5 (541 aa)
initn: 3301 init1: 3180 opt: 3187 Z-score: 2874.7 bits: 541.5 E(91774): 2.4e-153
Smith-Waterman score: 3187; 96.8% identity (98.4% similar) in 493 aa overlap (3-495:55-541)
10 20 30
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSY
:... :.. :... :::::::::::
NP_995 LPDRHGSPIPARGRLVMLPKVETEALGLARSHGEQGQMPENMQ------VSQFKMVNYSY
30 40 50 60 70
40 50 60 70 80 90
pF1KB5 DEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 DEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRC
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB5 PYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 PYCRFQKCLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQ
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB5 VIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 VIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGY
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB5 QTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 QTYGHFPSRAIKSEYPDPYTSSPESIMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQV
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB5 QAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 QAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLL
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB5 QNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 QNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB5 RSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 RSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQ
440 450 460 470 480 490
460 470 480 490
pF1KB5 LLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
:::::::::::::::::::::::::::::::::::::::::::
NP_995 LLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
500 510 520 530 540
>>NP_001263393 (OMIM: 604453) nuclear receptor subfamily (469 aa)
initn: 3149 init1: 3149 opt: 3149 Z-score: 2841.4 bits: 535.2 E(91774): 1.7e-151
Smith-Waterman score: 3149; 100.0% identity (100.0% similar) in 469 aa overlap (27-495:1-469)
10 20 30 40 50 60
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
::::::::::::::::::::::::::::::::::
NP_001 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
10 20 30
70 80 90 100 110 120
pF1KB5 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV
400 410 420 430 440 450
490
pF1KB5 PYNNLLIEMLHAKRA
:::::::::::::::
NP_001 PYNNLLIEMLHAKRA
460
>>XP_005245119 (OMIM: 604453) nuclear receptor subfamily (469 aa)
initn: 3149 init1: 3149 opt: 3149 Z-score: 2841.4 bits: 535.2 E(91774): 1.7e-151
Smith-Waterman score: 3149; 100.0% identity (100.0% similar) in 469 aa overlap (27-495:1-469)
10 20 30 40 50 60
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
::::::::::::::::::::::::::::::::::
XP_005 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
10 20 30
70 80 90 100 110 120
pF1KB5 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV
400 410 420 430 440 450
490
pF1KB5 PYNNLLIEMLHAKRA
:::::::::::::::
XP_005 PYNNLLIEMLHAKRA
460
>>XP_011507684 (OMIM: 604453) nuclear receptor subfamily (469 aa)
initn: 3149 init1: 3149 opt: 3149 Z-score: 2841.4 bits: 535.2 E(91774): 1.7e-151
Smith-Waterman score: 3149; 100.0% identity (100.0% similar) in 469 aa overlap (27-495:1-469)
10 20 30 40 50 60
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
::::::::::::::::::::::::::::::::::
XP_011 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
10 20 30
70 80 90 100 110 120
pF1KB5 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPESIMG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMC
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSIFLV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKNLEN
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLNGDV
400 410 420 430 440 450
490
pF1KB5 PYNNLLIEMLHAKRA
:::::::::::::::
XP_011 PYNNLLIEMLHAKRA
460
>>NP_004950 (OMIM: 184757,612964,612965,613957,617480) s (461 aa)
initn: 1857 init1: 879 opt: 1900 Z-score: 1719.2 bits: 327.5 E(91774): 5.4e-89
Smith-Waterman score: 1901; 61.5% identity (82.6% similar) in 470 aa overlap (28-494:1-460)
10 20 30 40 50 60
pF1KB5 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESC
..:::::::.:::::::::::::::::::::::
NP_004 MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESC
10 20 30
70 80 90 100 110 120
pF1KB5 KGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRGGRN
::::::::::::.::: :.:.:.::::::::::.:::::::.:::.::::::::::::::
NP_004 KGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRN
40 50 60 70 80 90
130 140 150 160 170
pF1KB5 KFGPMYKRDRALKQQKKALIRANGLKLEAMSQV-IQAMPSDLTISSAIQNIHSAS-KGLP
:::::::::::::::::: :::::.:::. . . : ..:. :::
NP_004 KFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGL-
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 LNHAALPPTDYDRSPFVTSPISMTMP-PHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPES
:: ::. . : . . :..: :: : :: : ::.::::::::.::.: :.
NP_004 ---AAGPPAG-PLGDFGAPALPMAVPGAHGPLAGY-LYPAFPGRAIKSEYPEPYASPPQP
160 170 180 190 200
240 250 260 270 280 290
pF1KB5 IMGYSYMDSYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFG
. :.: . . ...: ..:.:::.::. :::: ::.:.:.. ::. ..:. .. ..::
NP_004 GLPYGYPEPF-SGGP-NVPELILQLLQLEPDEDQVRARILGCLQEP--TKSRPDQPAAFG
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB5 LMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKEGSI
:.:.:::::..:::.::: . :.::.: ::: ::::::::::..::::::: :::::::
NP_004 LLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSI
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB5 FLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN
.:::::.:. . .:.:::. :..:. .::::: .: .::.:..:::::::..:::::.:
NP_004 LLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKF
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB5 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN
:.: ::. .::..::::::::.:.::. .:: :::: : :.::.::::.::::.:::.
NP_004 LNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLG
390 400 410 420 430 440
480 490
pF1KB5 GDVPYNNLLIEMLHAKRA
...: ::::::::.::.
NP_004 NEMPRNNLLIEMLQAKQT
450 460
495 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:50:05 2019 done: Tue Jul 16 15:50:06 2019
Total Scan time: 4.490 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]