Result of FASTA (omim) for
pF1KB8640
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8640, 203 aa
1>>>pF1KB8640 203 - 203 aa - 203 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9572+/-0.000301; mu= 16.7593+/- 0.019
mean_var=84.9320+/-17.094, 0's: 0 Z-trim(120.4): 149 B-trim: 1928 in 2/59
Lambda= 0.139168
statistics sampled from 35415 (35639) to 35415 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.418), width: 16
Scan time: 6.020
The best scores are: opt bits E(85289)
NP_006468 (OMIM: 602220) ras-like protein family m ( 203) 1416 293.1 2.1e-79
XP_011528125 (OMIM: 602220) PREDICTED: ras-like pr ( 155) 923 194.0 1.1e-49
XP_011528123 (OMIM: 602220) PREDICTED: ras-like pr ( 223) 924 194.3 1.2e-49
XP_011528124 (OMIM: 602220) PREDICTED: ras-like pr ( 223) 924 194.3 1.2e-49
NP_201572 (OMIM: 612128) ras-like protein family m ( 203) 676 144.5 1.1e-34
XP_016880790 (OMIM: 612128) PREDICTED: ras-like pr ( 203) 676 144.5 1.1e-34
XP_016880789 (OMIM: 612128) PREDICTED: ras-like pr ( 211) 434 95.9 4.9e-20
XP_016883322 (OMIM: 610388) PREDICTED: GTP-binding ( 306) 213 51.7 1.4e-06
XP_005260461 (OMIM: 610388) PREDICTED: GTP-binding ( 306) 213 51.7 1.4e-06
NP_996563 (OMIM: 612403) ras-like protein family m ( 242) 203 49.6 4.9e-06
NP_660156 (OMIM: 607862) GTP-binding protein Di-Ra ( 198) 202 49.3 4.9e-06
XP_011526015 (OMIM: 607862) PREDICTED: GTP-binding ( 232) 202 49.4 5.5e-06
XP_011527097 (OMIM: 610388) PREDICTED: GTP-binding ( 304) 192 47.5 2.6e-05
NP_055125 (OMIM: 612842) GTP-binding protein Rhes ( 266) 187 46.4 4.8e-05
XP_011528342 (OMIM: 612842) PREDICTED: GTP-binding ( 266) 187 46.4 4.8e-05
XP_005261499 (OMIM: 612842) PREDICTED: GTP-binding ( 266) 187 46.4 4.8e-05
XP_016884191 (OMIM: 612842) PREDICTED: GTP-binding ( 266) 187 46.4 4.8e-05
XP_016884190 (OMIM: 612842) PREDICTED: GTP-binding ( 278) 187 46.5 5e-05
NP_057168 (OMIM: 605550) dexamethasone-induced Ras ( 281) 187 46.5 5e-05
NP_775798 (OMIM: 616955) GTP-binding protein REM 2 ( 340) 186 46.3 6.6e-05
XP_016876548 (OMIM: 616955) PREDICTED: GTP-binding ( 372) 186 46.4 7e-05
NP_076429 (OMIM: 612404) ras-like protein family m ( 248) 182 45.4 9.2e-05
NP_001243749 (OMIM: 609591,615355) GTP-binding pro ( 183) 175 43.9 0.0002
NP_001238847 (OMIM: 179530) ras-related protein Ra ( 142) 172 43.1 0.00025
NP_001238846 (OMIM: 179530) ras-related protein Ra ( 142) 172 43.1 0.00025
XP_005267440 (OMIM: 616955) PREDICTED: GTP-binding ( 341) 176 44.3 0.00027
XP_016876547 (OMIM: 616955) PREDICTED: GTP-binding ( 373) 176 44.4 0.00028
XP_011534820 (OMIM: 616955) PREDICTED: GTP-binding ( 279) 160 41.0 0.0021
XP_011509876 (OMIM: 179551) PREDICTED: ras-related ( 195) 158 40.5 0.0022
NP_001300872 (OMIM: 165390) transforming protein R ( 187) 153 39.5 0.0043
NP_859053 (OMIM: 600164) GTP-binding protein GEM [ ( 296) 153 39.7 0.0059
NP_005252 (OMIM: 600164) GTP-binding protein GEM [ ( 296) 153 39.7 0.0059
NP_001318055 (OMIM: 612403) ras-like protein famil ( 200) 148 38.5 0.009
>>NP_006468 (OMIM: 602220) ras-like protein family membe (203 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1546.5 bits: 293.1 E(85289): 2.1e-79
Smith-Waterman score: 1416; 99.5% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 MGGSLRVAVLGAPGVGKTAIIRQFVFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_006 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALV
130 140 150 160 170 180
190 200
pF1KB8 RARPAHPALRLQGALHPARCSLM
:::::::::::::::::::::::
NP_006 RARPAHPALRLQGALHPARCSLM
190 200
>>XP_011528125 (OMIM: 602220) PREDICTED: ras-like protei (155 aa)
initn: 923 init1: 923 opt: 923 Z-score: 1013.0 bits: 194.0 E(85289): 1.1e-49
Smith-Waterman score: 923; 100.0% identity (100.0% similar) in 131 aa overlap (73-203:25-155)
50 60 70 80 90 100
pF1KB8 RPAVLLDGAVYDLSIRDGDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFD
::::::::::::::::::::::::::::::
XP_011 MRMSKDPLHPKHVSCGGSLHSWVQEEWPDAKDWSLQDTDAFVLVYDICSPDSFD
10 20 30 40 50
110 120 130 140 150 160
pF1KB8 YVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAK
60 70 80 90 100 110
170 180 190 200
pF1KB8 YNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
:::::::::::::::::::::::::::::::::::::::::
XP_011 YNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
120 130 140 150
>>XP_011528123 (OMIM: 602220) PREDICTED: ras-like protei (223 aa)
initn: 923 init1: 923 opt: 924 Z-score: 1012.2 bits: 194.3 E(85289): 1.2e-49
Smith-Waterman score: 924; 94.4% identity (95.1% similar) in 142 aa overlap (62-203:85-223)
40 50 60 70 80 90
pF1KB8 RHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVL
: : : . :::::::::::::::::::
XP_011 RGLSGASVGASSVWKSGRGSGWEGASILERVRGAGHAE---EEWPDAKDWSLQDTDAFVL
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB8 VYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRG
120 130 140 150 160 170
160 170 180 190 200
pF1KB8 WRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
180 190 200 210 220
>>XP_011528124 (OMIM: 602220) PREDICTED: ras-like protei (223 aa)
initn: 923 init1: 923 opt: 924 Z-score: 1012.2 bits: 194.3 E(85289): 1.2e-49
Smith-Waterman score: 924; 94.4% identity (95.1% similar) in 142 aa overlap (62-203:85-223)
40 50 60 70 80 90
pF1KB8 RHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVL
: : : . :::::::::::::::::::
XP_011 RGLSGASVGASSVWKSGRGSGWEGASILERVRGAGHAE---EEWPDAKDWSLQDTDAFVL
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB8 VYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRG
120 130 140 150 160 170
160 170 180 190 200
pF1KB8 WRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
180 190 200 210 220
>>NP_201572 (OMIM: 612128) ras-like protein family membe (203 aa)
initn: 615 init1: 426 opt: 676 Z-score: 743.6 bits: 144.5 E(85289): 1.1e-34
Smith-Waterman score: 676; 52.4% identity (74.5% similar) in 208 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 MGGSLRVAVLGAPGVGKTAIIRQFVFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG
: .. ::::::: ::::.::.:::..... : :: . ::: :::...: :.::.: :
NP_201 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILD-
10 20 30 40 50
70 80 90 100 110
pF1KB8 DVAGPGSS-PGGP-EEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAG
: :. : . .:: :. .:... :..:::::: :::.:::..::.: ::: :
NP_201 --FPPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 APEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR--
. :.::..:::::: :: : :: .. :::. :.:::.:::::::::.: :: :::.
NP_201 TSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV
120 130 140 150 160 170
180 190 200
pF1KB8 -CALVRARPAHPALRLQGALHPARCSLM
:: : . .: :::.::::. ::..:
NP_201 GCA--RCKHVHAALRFQGALRRNRCAIM
180 190 200
>>XP_016880790 (OMIM: 612128) PREDICTED: ras-like protei (203 aa)
initn: 615 init1: 426 opt: 676 Z-score: 743.6 bits: 144.5 E(85289): 1.1e-34
Smith-Waterman score: 676; 52.4% identity (74.5% similar) in 208 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 MGGSLRVAVLGAPGVGKTAIIRQFVFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG
: .. ::::::: ::::.::.:::..... : :: . ::: :::...: :.::.: :
XP_016 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILD-
10 20 30 40 50
70 80 90 100 110
pF1KB8 DVAGPGSS-PGGP-EEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAG
: :. : . .:: :. .:... :..:::::: :::.:::..::.: ::: :
XP_016 --FPPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 APEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR--
. :.::..:::::: :: : :: .. :::. :.:::.:::::::::.: :: :::.
XP_016 TSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSV
120 130 140 150 160 170
180 190 200
pF1KB8 -CALVRARPAHPALRLQGALHPARCSLM
:: : . .: :::.::::. ::..:
XP_016 GCA--RCKHVHAALRFQGALRRNRCAIM
180 190 200
>>XP_016880789 (OMIM: 612128) PREDICTED: ras-like protei (211 aa)
initn: 442 init1: 257 opt: 434 Z-score: 480.8 bits: 95.9 E(85289): 4.9e-20
Smith-Waterman score: 434; 49.3% identity (73.3% similar) in 150 aa overlap (1-148:60-206)
10 20 30
pF1KB8 MGGSLRVAVLGAPGVGKTAIIRQFVFGDYP
: .. ::::::: ::::.::.:::.....
XP_016 TVAEPPAPGICSPGEPQTAARTRWRSGAGGMVSTYRVAVLGARGVGKSAIVRQFLYNEFS
30 40 50 60 70 80
40 50 60 70 80
pF1KB8 ERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGPGSS-PGGP-EEWPDAKDWSLQDTDA
: :: . ::: :::...: :.::.: : : :. : . .:: :. .:... :
XP_016 EVCVPTTARRLYLPAVVMNGHVHDLQILDFP---PISAFPVNTLQEWADTCCRGLRSVHA
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB8 FVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALV
..:::::: :::.:::..::.: ::: :. :.::..:::::: :: : :: .. :.
XP_016 YILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLI
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB8 RRGWRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
XP_016 LAASL
210
>>XP_016883322 (OMIM: 610388) PREDICTED: GTP-binding pro (306 aa)
initn: 166 init1: 109 opt: 213 Z-score: 239.0 bits: 51.7 E(85289): 1.4e-06
Smith-Waterman score: 213; 32.4% identity (54.8% similar) in 188 aa overlap (6-183:82-256)
10 20 30
pF1KB8 MGGSLRVAVLGAPGVGKTAIIRQFVFGDYPERHRP
::..:: ::::::.. :. . . :.
XP_016 LNPPTQKPSPAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQ
60 70 80 90 100 110
40 50 60 70 80
pF1KB8 TDGPRLYRPAVLLDGAVYDLSIRDGDVAGPGSSPGGPEEWPDAK---DWS----LQDTDA
: : :.: : ::. : : : .. . : : .:: :: .:
XP_016 LGDPAL--PSVAED--VYE---RTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSA
120 130 140 150 160
90 100 110 120 130 140
pF1KB8 FVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLR---FGPRRALA
.:.::.: . ::. .. :: .. .:. : ..::..:::: : : : :: :
XP_016 YVIVYSIADRGSFESASELRIQLRRTHQAD--HVPIILVGNKADLARCREVSVEEGRACA
170 180 190 200 210 220
150 160 170 180 190 200
pF1KB8 ALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
.. . : ..: :: . .: .::. ..: .: :
XP_016 VV----FDCKFIETSATLQHNVAELFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARR
230 240 250 260 270
XP_016 FLARLTARSARRRALKARSKSCHNLAVL
280 290 300
>>XP_005260461 (OMIM: 610388) PREDICTED: GTP-binding pro (306 aa)
initn: 166 init1: 109 opt: 213 Z-score: 239.0 bits: 51.7 E(85289): 1.4e-06
Smith-Waterman score: 213; 32.4% identity (54.8% similar) in 188 aa overlap (6-183:82-256)
10 20 30
pF1KB8 MGGSLRVAVLGAPGVGKTAIIRQFVFGDYPERHRP
::..:: ::::::.. :. . . :.
XP_005 LNPPTQKPSPAPDDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQ
60 70 80 90 100 110
40 50 60 70 80
pF1KB8 TDGPRLYRPAVLLDGAVYDLSIRDGDVAGPGSSPGGPEEWPDAK---DWS----LQDTDA
: : :.: : ::. : : : .. . : : .:: :: .:
XP_005 LGDPAL--PSVAED--VYE---RTLTVDGEDTTLVVVDTWEAEKLDKSWSQESCLQGGSA
120 130 140 150 160
90 100 110 120 130 140
pF1KB8 FVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLR---FGPRRALA
.:.::.: . ::. .. :: .. .:. : ..::..:::: : : : :: :
XP_005 YVIVYSIADRGSFESASELRIQLRRTHQAD--HVPIILVGNKADLARCREVSVEEGRACA
170 180 190 200 210 220
150 160 170 180 190 200
pF1KB8 ALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
.. . : ..: :: . .: .::. ..: .: :
XP_005 VV----FDCKFIETSATLQHNVAELFEGVVRQLRLRRRDSAAKEPPAPRRPASLAQRARR
230 240 250 260 270
XP_005 FLARLTARSARRRALKARSKSCHNLAVL
280 290 300
>>NP_996563 (OMIM: 612403) ras-like protein family membe (242 aa)
initn: 127 init1: 63 opt: 203 Z-score: 229.4 bits: 49.6 E(85289): 4.9e-06
Smith-Waterman score: 203; 33.8% identity (63.8% similar) in 130 aa overlap (5-132:28-150)
10 20 30
pF1KB8 MGGSLRVAVLGAPGVGKTAIIRQFVFGDYPERHRPTD
...::::: :::.:.: .:. . ..:.
NP_996 MRPLSMSGHFLLAPIPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 GPRLYRPAVLLDGAVYDLSIRD--GDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDI
: .:: : ..: .:.:.: : : : : . :. . .: ...:.:::.:
NP_996 G-KLYSRLVYVEGDQLSLQIQDTPGGVQIQDSLP----QVVDSLSKCVQWAEGFLLVYSI
70 80 90 100 110
100 110 120 130 140 150
pF1KB8 CSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCG
. ::. .. : :.: ...: . .::...:::: :
NP_996 TDYDSYLSIRPLYQHIRKVHPDS--KAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLF
120 130 140 150 160 170
160 170 180 190 200
pF1KB8 YLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM
NP_996 LEISTSENYEDVCDVFQHLCKEVSKMHGLSGERRRASIIPRPRSPNMQDLKRRFKQALSP
180 190 200 210 220 230
203 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:31:40 2016 done: Sat Nov 5 21:31:41 2016
Total Scan time: 6.020 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]