Result of FASTA (omim) for pF1KE1076
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1076, 296 aa
  1>>>pF1KE1076 296 - 296 aa - 296 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1416+/-0.000362; mu= 15.8644+/- 0.023
 mean_var=59.4428+/-11.742, 0's: 0 Z-trim(112.4): 26  B-trim: 359 in 2/55
 Lambda= 0.166351
 statistics sampled from 21332 (21358) to 21332 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.25), width:  16
 Scan time:  6.790

The best scores are:                                      opt bits E(85289)
NP_057043 (OMIM: 616715) thioredoxin-related trans ( 296) 1978 483.1 2.7e-136
NP_001137484 (OMIM: 616715) thioredoxin-related tr ( 258) 1172 289.7 4.1e-78
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432)  147 43.8 0.00072
NP_110382 (OMIM: 610527) thioredoxin-related trans ( 280)  143 42.7 0.00097
NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747)  144 43.2  0.0019
NP_061854 (OMIM: 607987) dnaJ homolog subfamily C  ( 793)  144 43.2   0.002


>>NP_057043 (OMIM: 616715) thioredoxin-related transmemb  (296 aa)
 initn: 1978 init1: 1978 opt: 1978  Z-score: 2567.8  bits: 483.1 E(85289): 2.7e-136
Smith-Waterman score: 1978; 100.0% identity (100.0% similar) in 296 aa overlap (1-296:1-296)

               10        20        30        40        50        60
pF1KE1 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 FDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 IVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
              190       200       210       220       230       240

              250       260       270       280       290      
pF1KE1 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
              250       260       270       280       290      

>>NP_001137484 (OMIM: 616715) thioredoxin-related transm  (258 aa)
 initn: 1172 init1: 1172 opt: 1172  Z-score: 1523.3  bits: 289.7 E(85289): 4.1e-78
Smith-Waterman score: 1646; 86.8% identity (87.2% similar) in 296 aa overlap (1-296:1-258)

               10        20        30        40        50        60
pF1KE1 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 FDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLC
       :::::::::::::::::::::::.                                    
NP_001 FDWREVEILMFLSAIVMMKNRRSM------------------------------------
               70        80                                        

              130       140       150       160       170       180
pF1KE1 IVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --FLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
             90       100       110       120       130       140  

              190       200       210       220       230       240
pF1KE1 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
            150       160       170       180       190       200  

              250       260       270       280       290      
pF1KE1 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
            210       220       230       240       250        

>>NP_110437 (OMIM: 616412) thioredoxin domain-containing  (432 aa)
 initn: 188 init1:  94 opt: 147  Z-score: 190.4  bits: 43.8 E(85289): 0.00072
Smith-Waterman score: 147; 32.7% identity (58.2% similar) in 98 aa overlap (160-254:82-176)

     130       140       150       160       170       180         
pF1KE1 PLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGL
                                     : ::: : . :: . : . ::. :::  ..
NP_110 ADGEDGQDPHSKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYN--SM
              60        70        80        90       100           

     190       200       210       220       230       240         
pF1KE1 NFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSW---TF
       . .:: :.. .: ...  : ..  ..  ::: ::. :.::..           .:   :.
NP_110 EDAKVYVAK-VDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTL
     110        120       130       140       150       160        

        250       260       270       280       290                
pF1KE1 SEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK          
       .:: :  :                                                    
NP_110 NEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWE
      170       180       190       200       210       220        

>>NP_110382 (OMIM: 610527) thioredoxin-related transmemb  (280 aa)
 initn:  97 init1:  97 opt: 143  Z-score: 188.1  bits: 42.7 E(85289): 0.00097
Smith-Waterman score: 143; 26.8% identity (54.5% similar) in 123 aa overlap (113-234:5-115)

             90       100       110       120       130        140 
pF1KE1 SITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEY-IKYF
                                     : : . : .. :.    :   : .  .. .
NP_110                           MAPSGSLAVPLAVLVLLLWGAPWTHGRRSNVRVI
                                         10        20        30    

             150       160       170       180       190       200 
pF1KE1 NDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTD
       .:..  : :: :    :..::.: :   ::.. : . ...   .   .:..:::: .   
NP_110 TDENWRELLEGD----WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPG
           40            50        60        70        80        90

             210       220       230       240       250       260 
pF1KE1 VSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELY
       .: :. ...      :::.   . :.  .:: :                           
NP_110 LSGRFIITA------LPTIYHCKDGE--FRRYQGPRTKKDFINFISDKEWKSIEPVSSWF
                    100       110         120       130       140  

             270       280       290                               
pF1KE1 QRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK                         
                                                                   
NP_110 GPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGSYTVFALATLFSGLLLGLCMIFV
            150       160       170       180       190       200  

>>NP_001258510 (OMIM: 607987) dnaJ homolog subfamily C m  (747 aa)
 initn:  97 init1:  97 opt: 144  Z-score: 182.9  bits: 43.2 E(85289): 0.0019
Smith-Waterman score: 144; 23.3% identity (62.1% similar) in 116 aa overlap (135-249:623-732)

          110       120       130       140       150       160    
pF1KE1 FFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFA
                                     :.    .. .:..:.. . :   :...:.:
NP_001 PKSNKAYHYHSYNGWNRDAYSLRIWGLGFLPQVSTDLTPQTFSEKVLQGKN-HWVIDFYA
            600       610       620       630       640        650 

          170       180       190       200       210       220    
pF1KE1 NWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQ
        : . ::.::: . .:  ..    .. ::::   :...  .  . . : .:    . ...
NP_001 PWCGPCQNFAPEF-ELLARMIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVK----FYFYE
             660        670       680       690       700          

          230        240       250       260       270       280   
pF1KE1 GGKEAMRRPQIDKK-GRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVAST
        .:. ... ::. . ..:..  .::.                                  
NP_001 RAKRNFQEEQINTRDAKAIAALISEKLETLRNQGKRNKDEL                   
        710       720       730       740                          

>>NP_061854 (OMIM: 607987) dnaJ homolog subfamily C memb  (793 aa)
 initn:  97 init1:  97 opt: 144  Z-score: 182.5  bits: 43.2 E(85289): 0.002
Smith-Waterman score: 144; 23.3% identity (62.1% similar) in 116 aa overlap (135-249:669-778)

          110       120       130       140       150       160    
pF1KE1 FFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFA
                                     :.    .. .:..:.. . :   :...:.:
NP_061 PKSNKAYHYHSYNGWNRDAYSLRIWGLGFLPQVSTDLTPQTFSEKVLQGKN-HWVIDFYA
      640       650       660       670       680        690       

          170       180       190       200       210       220    
pF1KE1 NWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQ
        : . ::.::: . .:  ..    .. ::::   :...  .  . . : .:    . ...
NP_061 PWCGPCQNFAPEF-ELLARMIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVK----FYFYE
       700       710        720       730       740           750  

          230        240       250       260       270       280   
pF1KE1 GGKEAMRRPQIDKK-GRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVAST
        .:. ... ::. . ..:..  .::.                                  
NP_061 RAKRNFQEEQINTRDAKAIAALISEKLETLRNQGKRNKDEL                   
            760       770       780       790                      




296 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:33:36 2016 done: Sat Nov  5 19:33:37 2016
 Total Scan time:  6.790 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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