Result of FASTA (omim) for pF1KE1034
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1034, 424 aa
  1>>>pF1KE1034 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4691+/-0.000374; mu= 17.0500+/- 0.023
 mean_var=77.5265+/-15.991, 0's: 0 Z-trim(113.6): 51  B-trim: 296 in 1/54
 Lambda= 0.145663
 statistics sampled from 23017 (23059) to 23017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.27), width:  16
 Scan time:  9.460

The best scores are:                                      opt bits E(85289)
NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase,  ( 424) 2767 591.1 1.7e-168
XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 279) 1802 388.2 1.4e-107
XP_006713185 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 364) 1792 386.2 7.4e-107
XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 272) 1753 377.9 1.7e-104
NP_001123882 (OMIM: 604054) 3-ketoacyl-CoA thiolas ( 331) 1020 223.9 4.7e-58
NP_005882 (OMIM: 100678,614055) acetyl-CoA acetylt ( 397)  843 186.8 8.6e-47
NP_001290182 (OMIM: 100678,614055) acetyl-CoA acet ( 426)  827 183.4 9.3e-46
NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase,  ( 397)  805 178.8 2.2e-44
NP_000010 (OMIM: 203750,607809) acetyl-CoA acetylt ( 427)  663 149.0 2.2e-35
XP_016873170 (OMIM: 203750,607809) PREDICTED: acet ( 337)  635 143.0 1.1e-33
XP_006718898 (OMIM: 203750,607809) PREDICTED: acet ( 337)  635 143.0 1.1e-33
XP_016873172 (OMIM: 203750,607809) PREDICTED: acet ( 301)  515 117.8 3.9e-26
XP_016873171 (OMIM: 203750,607809) PREDICTED: acet ( 301)  515 117.8 3.9e-26
NP_001268441 (OMIM: 143450,609015) trifunctional e ( 459)  364 86.2 1.9e-16
NP_000174 (OMIM: 143450,609015) trifunctional enzy ( 474)  189 49.4 2.3e-05
XP_011531105 (OMIM: 143450,609015) PREDICTED: trif ( 474)  189 49.4 2.3e-05
XP_016859428 (OMIM: 143450,609015) PREDICTED: trif ( 481)  189 49.4 2.4e-05
NP_001268442 (OMIM: 143450,609015) trifunctional e ( 452)  186 48.7 3.5e-05


>>NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, pero  (424 aa)
 initn: 2767 init1: 2767 opt: 2767  Z-score: 3145.8  bits: 591.1 E(85289): 1.7e-168
Smith-Waterman score: 2767; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)

               10        20        30        40        50        60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
              370       380       390       400       410       420

           
pF1KE1 YPGN
       ::::
NP_001 YPGN
           

>>XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA   (279 aa)
 initn: 1802 init1: 1802 opt: 1802  Z-score: 2052.4  bits: 388.2 E(85289): 1.4e-107
Smith-Waterman score: 1802; 100.0% identity (100.0% similar) in 279 aa overlap (146-424:1-279)

         120       130       140       150       160       170     
pF1KE1 LSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKAR
                                     ::::::::::::::::::::::::::::::
XP_011                               MACGVESMSLADRGNPGNITSRLMEKEKAR
                                             10        20        30

         180       190       200       210       220       230     
pF1KE1 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
               40        50        60        70        80        90

         240       250       260       270       280       290     
pF1KE1 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
              100       110       120       130       140       150

         300       310       320       330       340       350     
pF1KE1 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
              160       170       180       190       200       210

         360       370       380       390       400       410     
pF1KE1 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
              220       230       240       250       260       270

         420    
pF1KE1 AAVFEYPGN
       :::::::::
XP_011 AAVFEYPGN
                

>>XP_006713185 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA   (364 aa)
 initn: 1789 init1: 1789 opt: 1792  Z-score: 2039.4  bits: 386.2 E(85289): 7.4e-107
Smith-Waterman score: 2261; 85.8% identity (85.8% similar) in 424 aa overlap (1-424:1-364)

               10        20        30        40        50        60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
       :::::::::::::::::::::::::::::::::                           
XP_006 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAG---------------------------
              250       260       270                              

              310       320       330       340       350       360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
                                        :::::::::::::::::::::::::::
XP_006 ---------------------------------LTVSDVDIFEINEAFASQAAYCVEKLR
                                            280       290       300

              370       380       390       400       410       420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
              310       320       330       340       350       360

           
pF1KE1 YPGN
       ::::
XP_006 YPGN
           

>>XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA   (272 aa)
 initn: 1753 init1: 1753 opt: 1753  Z-score: 1996.9  bits: 377.9 E(85289): 1.7e-104
Smith-Waterman score: 1753; 100.0% identity (100.0% similar) in 272 aa overlap (153-424:1-272)

            130       140       150       160       170       180  
pF1KE1 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIPMG
                                     ::::::::::::::::::::::::::::::
XP_006                               MSLADRGNPGNITSRLMEKEKARDCLIPMG
                                             10        20        30

            190       200       210       220       230       240  
pF1KE1 ITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITV
               40        50        60        70        80        90

            250       260       270       280       290       300  
pF1KE1 TQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILG
              100       110       120       130       140       150

            310       320       330       340       350       360  
pF1KE1 VLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLP
              160       170       180       190       200       210

            370       380       390       400       410       420  
pF1KE1 PEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYP
              220       230       240       250       260       270

         
pF1KE1 GN
       ::
XP_006 GN
         

>>NP_001123882 (OMIM: 604054) 3-ketoacyl-CoA thiolase, p  (331 aa)
 initn: 1621 init1: 1020 opt: 1020  Z-score: 1163.2  bits: 223.9 E(85289): 4.7e-58
Smith-Waterman score: 1966; 78.1% identity (78.1% similar) in 424 aa overlap (1-424:1-331)

               10        20        30        40        50        60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
       :::::::::::::::::::::::::::::                               
NP_001 RQCSSGLQAVASIAGGIRNGSYDIGMACG-------------------------------
              130       140                                        

              190       200       210       220       230       240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --ITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
       150       160       170       180       190       200       

              250       260       270       280       290       300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
       :::::::::::::::::::::::::::::::::                           
NP_001 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAG---------------------------
       210       220       230       240                           

              310       320       330       340       350       360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
                                        :::::::::::::::::::::::::::
NP_001 ---------------------------------LTVSDVDIFEINEAFASQAAYCVEKLR
                                               250       260       

              370       380       390       400       410       420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
       270       280       290       300       310       320       

           
pF1KE1 YPGN
       ::::
NP_001 YPGN
       330 

>>NP_005882 (OMIM: 100678,614055) acetyl-CoA acetyltrans  (397 aa)
 initn: 817 init1: 414 opt: 843  Z-score: 961.1  bits: 186.8 E(85289): 8.6e-47
Smith-Waterman score: 843; 41.7% identity (66.6% similar) in 398 aa overlap (33-416:3-391)

             10        20        30        40        50        60  
pF1KE1 RLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPD
                                     :..  ::.: . :: :  .  :..  .  .
NP_005                             MNAGSDPVVIVSAARTIIG-SFNGALAAVPVQ
                                           10         20        30 

             70        80        90       100       110       120  
pF1KE1 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ
       .: :.:.  ::: ... ::.....  :.::  : :   .: :.  . :: .::  . .  
NP_005 DLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMI
              40        50        60        70        80        90 

            130       140       150                 160       170  
pF1KE1 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR----------GNPGNITSRLME--
       :.:::.::   . .:  :. .: .: :.:.:: : .          :.     : : .  
NP_005 CGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGL
             100       110       120       130       140       150 

              180       190       200       210       220       230
pF1KE1 KEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTV
        .  ..:   ::::.::::... .::: ::  :. ::...  ::. : :. ::::: ...
NP_005 TDAFHNC--HMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVST
               160       170       180       190       200         

              240       250       260         270       280        
pF1KE1 HDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGS--TTAGNSSQVSDGAAAILLA
       .  ::    : :  ::  : ....:...:::: :  ::.  .: .:.: ..:::::..: 
NP_005 R--KGL---IEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLM
     210            220       230       240       250       260    

      290       300       310       320       330       340        
pF1KE1 RRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAF
       ..:.:.. ::  :. . :.. ::: :.::::::  ::  :. ::: .. :::::::::::
NP_005 KKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAF
          270       280       290       300       310       320    

      350       360       370       380       390       400        
pF1KE1 ASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMC
       :. .:  :..: : :::::  :::.::::::: .: : ..:::. :.: : :. ::...:
NP_005 AAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAALC
          330       340       350       360       370        380   

      410       420    
pF1KE1 IGTGMGAAAVFEYPGN
       :: ::: :        
NP_005 IGGGMGIAMCVQRE  
           390         

>>NP_001290182 (OMIM: 100678,614055) acetyl-CoA acetyltr  (426 aa)
 initn: 817 init1: 414 opt: 827  Z-score: 942.5  bits: 183.4 E(85289): 9.3e-46
Smith-Waterman score: 827; 42.2% identity (67.1% similar) in 377 aa overlap (54-416:52-420)

            30        40        50        60        70        80   
pF1KE1 APCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQL
                                     :..  .  ..: :.:.  ::: ... ::..
NP_001 RSGGRLSSPRLLRVVAPTLTFAQTSRCSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDV
              30        40        50        60        70        80 

            90       100       110       120       130       140   
pF1KE1 GDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYD
       ...  :.::  : :   .: :.  . :: .::  . .  :.:::.::   . .:  :. .
NP_001 SEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSS
              90       100       110       120       130       140 

           150                 160       170         180       190 
pF1KE1 IGMACGVESMSLADR----------GNPGNITSRLME--KEKARDCLIPMGITSENVAER
       : .: :.:.:: : .          :.     : : .   .  ..:   ::::.::::..
NP_001 IVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNC--HMGITAENVAKK
             150       160       170       180         190         

             200       210       220       230       240       250 
pF1KE1 FGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPS
       . .::: ::  :. ::...  ::. : :. ::::: ....  ::    : :  ::  : .
NP_001 WQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTR--KGL---IEVKTDEFPRHG
     200       210       220       230         240          250    

             260         270       280       290       300         
pF1KE1 TTMEGLAKLKPAFKKDGS--TTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAV
       ...:...:::: :  ::.  .: .:.: ..:::::..: ..:.:.. ::  :. . :.. 
NP_001 SNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQ
          260       270       280       290       300       310    

     310       320       330       340       350       360         
pF1KE1 VGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPL
       ::: :.::::::  ::  :. ::: .. ::::::::::::. .:  :..: : :::::  
NP_001 VGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIE
          320       330       340       350       360       370    

     370       380       390       400       410       420    
pF1KE1 GGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN
       :::.::::::: .: : ..:::. :.: : :. ::...::: ::: :        
NP_001 GGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAALCIGGGMGIAMCVQRE  
          380       390       400        410       420        

>>NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, mito  (397 aa)
 initn: 774 init1: 477 opt: 805  Z-score: 917.9  bits: 178.8 E(85289): 2.2e-44
Smith-Waterman score: 805; 39.2% identity (65.6% similar) in 395 aa overlap (38-420:7-394)

        10        20        30        40        50        60       
pF1KE1 LGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSA
                                     : :: ..:: .   : : .:: :  .:   
NP_006                         MALLRGVFVVAAKRTPFGAYG-GLLKDFTATDLSEF
                                       10        20         30     

        70        80        90        100       110       120      
pF1KE1 VMTAVLKDVNLRPEQLGDICVGNVLQPGAGAI-MARIAQFLSDIPETVPLSTVNRQCSSG
       .  :.:.  .. :: . .. .::::: .. :: .:: . .   ::. .:  :.:: :.::
NP_006 AAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSG
          40        50        60        70        80        90     

        130       140       150                  160       170     
pF1KE1 LQAVASIAGGIRNGSYDIGMACGVESMSLADR-----------GNPGNITSRLMEKEKAR
       .:....    :     .. .  :.:::: :             :.  .. . :  .   .
NP_006 FQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQ
         100       110       120       130       140       150     

         180       190       200       210       220       230     
pF1KE1 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
          .::..:.::.: .  ::::. : .:: :::.   :.. : :. :..:.   :.  ::
NP_006 HVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPI--EVKTKKG
         160       170       180       190       200         210   

         240       250       260       270       280       290     
pF1KE1 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
        :... :  ::  ::.::.: : :: :.:::::..::::.: :.:::.:...: .. ...
NP_006 -KQTMQV--DEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKK
              220       230       240       250       260       270

         300       310       320       330       340       350     
pF1KE1 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
        ..  :. . .: : :  :.::::::. ::  ::.::::...:.:. :.::::: :    
NP_006 HNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAV
              280       290       300       310       320       330

         360       370       380       390       400       410     
pF1KE1 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
        ..: :   :.:  :::.::::::: .:.: .  :..::.::: . :.: : ::: :.: 
NP_006 ERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGK-YAVGSACIGGGQGI
              340       350       360       370        380         

         420    
pF1KE1 AAVFEYPGN
       :....    
NP_006 AVIIQSTA 
     390        

>>NP_000010 (OMIM: 203750,607809) acetyl-CoA acetyltrans  (427 aa)
 initn: 594 init1: 309 opt: 663  Z-score: 756.2  bits: 149.0 E(85289): 2.2e-35
Smith-Waterman score: 663; 33.6% identity (65.7% similar) in 402 aa overlap (28-419:32-423)

                  10        20        30        40        50       
pF1KE1    MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFK
                                     : . . .  .::.: . :: :  .  :...
NP_000 AVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIG-SFLGSLS
              10        20        30        40        50         60

        60        70        80        90       100       110       
pF1KE1 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS
            .: : .. .... ...  :.. .  .::::: : :   .: : . . .: ..: .
NP_000 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
               70        80        90       100       110       120

       120       130       140       150           160          170
pF1KE1 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRGN-P-GNITSR-LME
       :.:. :.::..:.   . ..  :  :. .: :.::::    . .::. : :..  . :. 
NP_000 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
              130       140       150       160       170       180

                180       190       200       210       220        
pF1KE1 KEKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTT
       :.   :    : ::  .::.:....:.:..::..:. :  ..  :   : :  :..:::.
NP_000 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
              190       200       210       220       230       240

      230       240       250       260        270       280       
pF1KE1 TVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILL
       ::   :: . ...: .::  .  . .  . ::: .:.:. :..::.:.: ..:::::..:
NP_000 TV---KG-QPDVVVKEDEEYK-RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVL
                  250        260       270       280       290     

       290       300       310       320       330       340       
pF1KE1 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
          . :..:..  :. . ..: ..: :  . :.:.::  ..:. .::   :. ..:.:::
NP_000 MTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEA
         300       310       320       330       340       350     

       350       360       370       380       390       400       
pF1KE1 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
       :.  .   .. :.. :.:::  ::::.::::.: .::: :  : . ::. :.  ::..:.
NP_000 FSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ-GE--YGLASI
         360       370       380       390       400          410  

       410       420    
pF1KE1 CIGTGMGAAAVFEYPGN
       : : : ::.:..     
NP_000 CNGGG-GASAMLIQKL 
             420        

>>XP_016873170 (OMIM: 203750,607809) PREDICTED: acetyl-C  (337 aa)
 initn: 582 init1: 309 opt: 635  Z-score: 725.9  bits: 143.0 E(85289): 1.1e-33
Smith-Waterman score: 635; 36.3% identity (67.3% similar) in 342 aa overlap (88-419:1-333)

        60        70        80        90       100       110       
pF1KE1 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS
                                     .::::: : :   .: : . . .: ..: .
XP_016                               MGNVLQGGEGQAPTRQAVLGAGLPISTPCT
                                             10        20        30

       120       130       140       150           160          170
pF1KE1 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRGN-P-GNITSR-LME
       :.:. :.::..:.   . ..  :  :. .: :.::::    . .::. : :..  . :. 
XP_016 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
               40        50        60        70        80        90

                180       190       200       210       220        
pF1KE1 KEKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTT
       :.   :    : ::  .::.:....:.:..::..:. :  ..  :   : :  :..:::.
XP_016 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
              100       110       120       130       140       150

      230       240       250       260        270       280       
pF1KE1 TVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILL
       ::   :: . ...: .::  .  . .  . ::: .:.:. :..::.:.: ..:::::..:
XP_016 TV---KG-QPDVVVKEDEEYK-RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVL
                  160        170       180       190       200     

       290       300       310       320       330       340       
pF1KE1 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
          . :..:..  :. . ..: ..: :  . :.:.::  ..:. .::   :. ..:.:::
XP_016 MTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEA
         210       220       230       240       250       260     

       350       360       370       380       390       400       
pF1KE1 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
       :.  .   .. :.. :.:::  ::::.::::.: .::: :  : . ::. :.  ::..:.
XP_016 FSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ-GE--YGLASI
         270       280       290       300       310          320  

       410       420    
pF1KE1 CIGTGMGAAAVFEYPGN
       : : : ::.:..     
XP_016 CNGGG-GASAMLIQKL 
             330        




424 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:40:11 2016 done: Sat Nov  5 07:40:13 2016
 Total Scan time:  9.460 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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