Result of FASTA (ccds) for pF1KE1034
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1034, 424 aa
  1>>>pF1KE1034 424 - 424 aa - 424 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0512+/-0.000894; mu= 13.3288+/- 0.053
 mean_var=74.4832+/-14.941, 0's: 0 Z-trim(106.8): 28  B-trim: 0 in 0/52
 Lambda= 0.148609
 statistics sampled from 9182 (9197) to 9182 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.283), width:  16
 Scan time:  3.000

The best scores are:                                      opt bits E(32554)
CCDS2673.1 ACAA1 gene_id:30|Hs108|chr3             ( 424) 2767 602.6 2.3e-172
CCDS46794.1 ACAA1 gene_id:30|Hs108|chr3            ( 331) 1020 228.1   1e-59
CCDS5268.1 ACAT2 gene_id:39|Hs108|chr6             ( 397)  843 190.1 3.2e-48
CCDS11939.1 ACAA2 gene_id:10449|Hs108|chr18        ( 397)  805 182.0   9e-46
CCDS8339.1 ACAT1 gene_id:38|Hs108|chr11            ( 427)  663 151.6 1.4e-36
CCDS62871.1 HADHB gene_id:3032|Hs108|chr2          ( 459)  364 87.5   3e-17


>>CCDS2673.1 ACAA1 gene_id:30|Hs108|chr3                  (424 aa)
 initn: 2767 init1: 2767 opt: 2767  Z-score: 3208.1  bits: 602.6 E(32554): 2.3e-172
Smith-Waterman score: 2767; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)

               10        20        30        40        50        60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
              370       380       390       400       410       420

           
pF1KE1 YPGN
       ::::
CCDS26 YPGN
           

>>CCDS46794.1 ACAA1 gene_id:30|Hs108|chr3                 (331 aa)
 initn: 1621 init1: 1020 opt: 1020  Z-score: 1185.6  bits: 228.1 E(32554): 1e-59
Smith-Waterman score: 1966; 78.1% identity (78.1% similar) in 424 aa overlap (1-424:1-331)

               10        20        30        40        50        60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
       :::::::::::::::::::::::::::::                               
CCDS46 RQCSSGLQAVASIAGGIRNGSYDIGMACG-------------------------------
              130       140                                        

              190       200       210       220       230       240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 --ITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
       150       160       170       180       190       200       

              250       260       270       280       290       300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
       :::::::::::::::::::::::::::::::::                           
CCDS46 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAG---------------------------
       210       220       230       240                           

              310       320       330       340       350       360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
                                        :::::::::::::::::::::::::::
CCDS46 ---------------------------------LTVSDVDIFEINEAFASQAAYCVEKLR
                                               250       260       

              370       380       390       400       410       420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
       270       280       290       300       310       320       

           
pF1KE1 YPGN
       ::::
CCDS46 YPGN
       330 

>>CCDS5268.1 ACAT2 gene_id:39|Hs108|chr6                  (397 aa)
 initn: 817 init1: 414 opt: 843  Z-score: 979.2  bits: 190.1 E(32554): 3.2e-48
Smith-Waterman score: 843; 41.7% identity (66.6% similar) in 398 aa overlap (33-416:3-391)

             10        20        30        40        50        60  
pF1KE1 RLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPD
                                     :..  ::.: . :: :  .  :..  .  .
CCDS52                             MNAGSDPVVIVSAARTIIG-SFNGALAAVPVQ
                                           10         20        30 

             70        80        90       100       110       120  
pF1KE1 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ
       .: :.:.  ::: ... ::.....  :.::  : :   .: :.  . :: .::  . .  
CCDS52 DLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMI
              40        50        60        70        80        90 

            130       140       150                 160       170  
pF1KE1 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR----------GNPGNITSRLME--
       :.:::.::   . .:  :. .: .: :.:.:: : .          :.     : : .  
CCDS52 CGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGL
             100       110       120       130       140       150 

              180       190       200       210       220       230
pF1KE1 KEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTV
        .  ..:   ::::.::::... .::: ::  :. ::...  ::. : :. ::::: ...
CCDS52 TDAFHNC--HMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVST
               160       170       180       190       200         

              240       250       260         270       280        
pF1KE1 HDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGS--TTAGNSSQVSDGAAAILLA
       .  ::    : :  ::  : ....:...:::: :  ::.  .: .:.: ..:::::..: 
CCDS52 R--KGL---IEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLM
     210            220       230       240       250       260    

      290       300       310       320       330       340        
pF1KE1 RRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAF
       ..:.:.. ::  :. . :.. ::: :.::::::  ::  :. ::: .. :::::::::::
CCDS52 KKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAF
          270       280       290       300       310       320    

      350       360       370       380       390       400        
pF1KE1 ASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMC
       :. .:  :..: : :::::  :::.::::::: .: : ..:::. :.: : :. ::...:
CCDS52 AAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAALC
          330       340       350       360       370        380   

      410       420    
pF1KE1 IGTGMGAAAVFEYPGN
       :: ::: :        
CCDS52 IGGGMGIAMCVQRE  
           390         

>>CCDS11939.1 ACAA2 gene_id:10449|Hs108|chr18             (397 aa)
 initn: 774 init1: 477 opt: 805  Z-score: 935.2  bits: 182.0 E(32554): 9e-46
Smith-Waterman score: 805; 39.2% identity (65.6% similar) in 395 aa overlap (38-420:7-394)

        10        20        30        40        50        60       
pF1KE1 LGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSA
                                     : :: ..:: .   : : .:: :  .:   
CCDS11                         MALLRGVFVVAAKRTPFGAYG-GLLKDFTATDLSEF
                                       10        20         30     

        70        80        90        100       110       120      
pF1KE1 VMTAVLKDVNLRPEQLGDICVGNVLQPGAGAI-MARIAQFLSDIPETVPLSTVNRQCSSG
       .  :.:.  .. :: . .. .::::: .. :: .:: . .   ::. .:  :.:: :.::
CCDS11 AAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSG
          40        50        60        70        80        90     

        130       140       150                  160       170     
pF1KE1 LQAVASIAGGIRNGSYDIGMACGVESMSLADR-----------GNPGNITSRLMEKEKAR
       .:....    :     .. .  :.:::: :             :.  .. . :  .   .
CCDS11 FQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQ
         100       110       120       130       140       150     

         180       190       200       210       220       230     
pF1KE1 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
          .::..:.::.: .  ::::. : .:: :::.   :.. : :. :..:.   :.  ::
CCDS11 HVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPI--EVKTKKG
         160       170       180       190       200         210   

         240       250       260       270       280       290     
pF1KE1 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
        :... :  ::  ::.::.: : :: :.:::::..::::.: :.:::.:...: .. ...
CCDS11 -KQTMQV--DEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKK
              220       230       240       250       260       270

         300       310       320       330       340       350     
pF1KE1 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
        ..  :. . .: : :  :.::::::. ::  ::.::::...:.:. :.::::: :    
CCDS11 HNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAV
              280       290       300       310       320       330

         360       370       380       390       400       410     
pF1KE1 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
        ..: :   :.:  :::.::::::: .:.: .  :..::.::: . :.: : ::: :.: 
CCDS11 ERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGK-YAVGSACIGGGQGI
              340       350       360       370        380         

         420    
pF1KE1 AAVFEYPGN
       :....    
CCDS11 AVIIQSTA 
     390        

>>CCDS8339.1 ACAT1 gene_id:38|Hs108|chr11                 (427 aa)
 initn: 594 init1: 309 opt: 663  Z-score: 770.2  bits: 151.6 E(32554): 1.4e-36
Smith-Waterman score: 663; 33.6% identity (65.7% similar) in 402 aa overlap (28-419:32-423)

                  10        20        30        40        50       
pF1KE1    MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFK
                                     : . . .  .::.: . :: :  .  :...
CCDS83 AVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIG-SFLGSLS
              10        20        30        40        50         60

        60        70        80        90       100       110       
pF1KE1 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS
            .: : .. .... ...  :.. .  .::::: : :   .: : . . .: ..: .
CCDS83 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
               70        80        90       100       110       120

       120       130       140       150           160          170
pF1KE1 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRGN-P-GNITSR-LME
       :.:. :.::..:.   . ..  :  :. .: :.::::    . .::. : :..  . :. 
CCDS83 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
              130       140       150       160       170       180

                180       190       200       210       220        
pF1KE1 KEKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTT
       :.   :    : ::  .::.:....:.:..::..:. :  ..  :   : :  :..:::.
CCDS83 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
              190       200       210       220       230       240

      230       240       250       260        270       280       
pF1KE1 TVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILL
       ::   :: . ...: .::  .  . .  . ::: .:.:. :..::.:.: ..:::::..:
CCDS83 TV---KG-QPDVVVKEDEEYK-RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVL
                  250        260       270       280       290     

       290       300       310       320       330       340       
pF1KE1 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
          . :..:..  :. . ..: ..: :  . :.:.::  ..:. .::   :. ..:.:::
CCDS83 MTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEA
         300       310       320       330       340       350     

       350       360       370       380       390       400       
pF1KE1 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
       :.  .   .. :.. :.:::  ::::.::::.: .::: :  : . ::. :.  ::..:.
CCDS83 FSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ-GE--YGLASI
         360       370       380       390       400          410  

       410       420    
pF1KE1 CIGTGMGAAAVFEYPGN
       : : : ::.:..     
CCDS83 CNGGG-GASAMLIQKL 
             420        

>>CCDS62871.1 HADHB gene_id:3032|Hs108|chr2               (459 aa)
 initn: 626 init1: 148 opt: 364  Z-score: 423.2  bits: 87.5 E(32554): 3e-17
Smith-Waterman score: 623; 33.2% identity (58.2% similar) in 455 aa overlap (22-422:33-458)

                        10        20        30             40      
pF1KE1          MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAA-----DVVVVHGRRT
                                     .::: ..   . . :     .:::: : ::
CCDS62 ILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRT
             10        20        30        40        50        60  

         50          60        70        80        90       100    
pF1KE1 AICRAGRGGF--KDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIA
        .  .: .:.  . ..: :... ..                   :.:.:    . .:: :
CCDS62 PFLLSGTSGLLHRTSVPKEVVDYII------------------FGTVIQEVKTSNVAREA
             70        80                          90       100    

          110       120       130       140       150              
pF1KE1 QFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----------
        . . . . .:  ::.  : :. ::... .: : .:. :. .: ::: ::          
CCDS62 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM
          110       120       130       140       150       160    

             160       170        180                    190       
pF1KE1 ---LADRGNPGNITSRLMEKEKAR-DCLIP-------------MGITSENVAERFGISRE
          . : ..  .. .::    : : . : :             :: ... .:  :..:: 
CCDS62 RKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRL
          170       180       190       200       210       220    

       200       210       220       230       240       250       
pF1KE1 KQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGL
       .:: .:: :.. : .::..: . ...::  .  .:        :::.:.:::::. .: .
CCDS62 EQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD--------TVTKDNGIRPSS-LEQM
          230       240        250               260       270     

       260        270       280       290       300       310      
pF1KE1 AKLKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPP-D
       ::::::: :  :..::.::: ..:::.:.:.  . ::  .:    . ::..  :.  : :
CCDS62 AKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKD
          280       290       300       310       320       330    

         320       330       340       350                         
pF1KE1 IMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQ---------AAYCVE-------KL
        . .::.:: : .:.:::::..:.: ::..:::..:         . . .:       :.
CCDS62 QLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKV
          340       350       360       370       380       390    

     360        370       380       390       400       410        
pF1KE1 RLPP-EKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAV
        ::: :: :  ::...::::.: :: : :..  :.:...: . ::.:. : . :.: : .
CCDS62 GLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQ-YGLVAACAAGGQGHAMI
          400       410       420       430        440       450   

      420     
pF1KE1 FE-YPGN
        : ::  
CCDS62 VEAYPK 
              




424 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:40:11 2016 done: Sat Nov  5 07:40:11 2016
 Total Scan time:  3.000 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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