Result of FASTA (omim) for pF1KB5446
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5446, 655 aa
  1>>>pF1KB5446 655 - 655 aa - 655 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2198+/-0.000409; mu= 20.6917+/- 0.025
 mean_var=76.1993+/-15.709, 0's: 0 Z-trim(111.7): 58  B-trim: 59 in 1/49
 Lambda= 0.146926
 statistics sampled from 20312 (20370) to 20312 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.239), width:  16
 Scan time:  7.980

The best scores are:                                      opt bits E(85289)
NP_000009 (OMIM: 201475,609575) very long-chain sp ( 655) 4259 912.8       0
NP_001257376 (OMIM: 201475,609575) very long-chain ( 678) 4133 886.1       0
XP_006721579 (OMIM: 201475,609575) PREDICTED: very ( 662) 4103 879.8       0
NP_001029031 (OMIM: 201475,609575) very long-chain ( 633) 3829 821.7       0
NP_001257377 (OMIM: 201475,609575) very long-chain ( 579) 3768 808.7       0
XP_011522132 (OMIM: 201475,609575) PREDICTED: very ( 621) 3120 671.4 2.7e-192
XP_011522131 (OMIM: 201475,609575) PREDICTED: very ( 628) 3120 671.4 2.8e-192
NP_054768 (OMIM: 611103,611126) acyl-CoA dehydroge ( 621) 1697 369.7 1.7e-101
XP_016861753 (OMIM: 611103,611126) PREDICTED: acyl ( 537) 1410 308.9 3.2e-83
XP_016877645 (OMIM: 243500,607036) PREDICTED: isov ( 407)  724 163.4 1.5e-39
NP_002216 (OMIM: 243500,607036) isovaleryl-CoA deh ( 426)  717 161.9 4.4e-39
NP_000008 (OMIM: 201470,606885) short-chain specif ( 412)  714 161.2 6.7e-39
NP_001152980 (OMIM: 243500,607036) isovaleryl-CoA  ( 396)  712 160.8 8.7e-39
NP_001600 (OMIM: 600301,610006) short/branched cha ( 432)  710 160.4 1.2e-38
XP_016877643 (OMIM: 243500,607036) PREDICTED: isov ( 436)  702 158.7 4.1e-38
XP_016877641 (OMIM: 243500,607036) PREDICTED: isov ( 455)  702 158.7 4.2e-38
NP_001317103 (OMIM: 600301,610006) short/branched  ( 330)  674 152.7   2e-36
XP_006720555 (OMIM: 243500,607036) PREDICTED: isov ( 447)  648 147.3 1.2e-34
XP_005254407 (OMIM: 243500,607036) PREDICTED: isov ( 487)  641 145.8 3.5e-34
NP_001272971 (OMIM: 201450,607008) medium-chain sp ( 385)  633 144.0 9.3e-34
NP_000007 (OMIM: 201450,607008) medium-chain speci ( 421)  633 144.1   1e-33
NP_001120800 (OMIM: 201450,607008) medium-chain sp ( 425)  633 144.1   1e-33
XP_016877640 (OMIM: 243500,607036) PREDICTED: isov ( 476)  633 144.1 1.1e-33
XP_016877638 (OMIM: 243500,607036) PREDICTED: isov ( 516)  626 142.7 3.3e-33
XP_016877639 (OMIM: 243500,607036) PREDICTED: isov ( 478)  623 142.0 4.8e-33
XP_016877644 (OMIM: 243500,607036) PREDICTED: isov ( 418)  617 140.7   1e-32
XP_016877642 (OMIM: 243500,607036) PREDICTED: isov ( 447)  617 140.7 1.1e-32
NP_001272972 (OMIM: 201450,607008) medium-chain sp ( 454)  611 139.4 2.7e-32
XP_016861754 (OMIM: 611103,611126) PREDICTED: acyl ( 340)  588 134.5 6.3e-31
XP_016873036 (OMIM: 604773,611283) PREDICTED: isob ( 317)  576 131.9 3.5e-30
XP_006720558 (OMIM: 243500,607036) PREDICTED: isov ( 347)  576 131.9 3.7e-30
NP_055199 (OMIM: 604773,611283) isobutyryl-CoA deh ( 415)  576 132.0 4.3e-30
XP_005246574 (OMIM: 609576) PREDICTED: long-chain  ( 409)  565 129.7 2.1e-29
NP_001599 (OMIM: 609576) long-chain specific acyl- ( 430)  565 129.7 2.2e-29
XP_016877646 (OMIM: 243500,607036) PREDICTED: isov ( 376)  561 128.8 3.6e-29
XP_016873035 (OMIM: 604773,611283) PREDICTED: isob ( 353)  551 126.6 1.5e-28
XP_016873031 (OMIM: 604773,611283) PREDICTED: isob ( 451)  551 126.7 1.8e-28
XP_011541052 (OMIM: 604773,611283) PREDICTED: isob ( 451)  551 126.7 1.8e-28
XP_016873032 (OMIM: 604773,611283) PREDICTED: isob ( 434)  539 124.2   1e-27
XP_016859444 (OMIM: 609576) PREDICTED: long-chain  ( 289)  505 116.8 1.1e-25
NP_001289483 (OMIM: 201470,606885) short-chain spe ( 408)  481 111.8 4.9e-24
XP_016877647 (OMIM: 243500,607036) PREDICTED: isov ( 308)  466 108.6 3.6e-23
XP_016873034 (OMIM: 604773,611283) PREDICTED: isob ( 391)  446 104.4 8.1e-22
XP_016873033 (OMIM: 604773,611283) PREDICTED: isob ( 391)  446 104.4 8.1e-22
NP_001272973 (OMIM: 201450,607008) medium-chain sp ( 232)  436 102.1 2.4e-21
XP_005271562 (OMIM: 604773,611283) PREDICTED: isob ( 249)  342 82.2 2.5e-15
XP_016873038 (OMIM: 604773,611283) PREDICTED: isob ( 249)  342 82.2 2.5e-15
XP_016873037 (OMIM: 604773,611283) PREDICTED: isob ( 268)  340 81.8 3.5e-15
NP_115545 (OMIM: 614288) acyl-CoA dehydrogenase fa ( 780)  339 82.0 9.2e-15
NP_079523 (OMIM: 611181) acyl-CoA dehydrogenase fa (1059)  339 82.1 1.2e-14


>>NP_000009 (OMIM: 201475,609575) very long-chain specif  (655 aa)
 initn: 4259 init1: 4259 opt: 4259  Z-score: 4877.7  bits: 912.8 E(85289):    0
Smith-Waterman score: 4259; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)

               10        20        30        40        50        60
pF1KB5 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB5 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK
              550       560       570       580       590       600

              610       620       630       640       650     
pF1KB5 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
              610       620       630       640       650     

>>NP_001257376 (OMIM: 201475,609575) very long-chain spe  (678 aa)
 initn: 4133 init1: 4133 opt: 4133  Z-score: 4733.1  bits: 886.1 E(85289):    0
Smith-Waterman score: 4133; 100.0% identity (100.0% similar) in 635 aa overlap (21-655:44-678)

                         10        20        30        40        50
pF1KB5           MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALD
                                     ::::::::::::::::::::::::::::::
NP_001 MGKEIEAEAQRPLRQTWRPGQPPAMTAKTMSSRLTALLGQPRPGPARRPYAGGAAQLALD
            20        30        40        50        60        70   

               60        70        80        90       100       110
pF1KB5 KSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVS
            80        90       100       110       120       130   

              120       130       140       150       160       170
pF1KB5 RFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMH
           140       150       160       170       180       190   

              180       190       200       210       220       230
pF1KB5 DLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRT
           200       210       220       230       240       250   

              240       250       260       270       280       290
pF1KB5 SAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGG
           260       270       280       290       300       310   

              300       310       320       330       340       350
pF1KB5 ITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAG
           320       330       340       350       360       370   

              360       370       380       390       400       410
pF1KB5 TMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATD
           380       390       400       410       420       430   

              420       430       440       450       460       470
pF1KB5 FQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRL
           440       450       460       470       480       490   

              480       490       500       510       520       530
pF1KB5 FVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELS
           500       510       520       530       540       550   

              540       550       560       570       580       590
pF1KB5 RSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLS
           560       570       580       590       600       610   

              600       610       620       630       640       650
pF1KB5 EGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTS
           620       630       640       650       660       670   

            
pF1KB5 NPLGF
       :::::
NP_001 NPLGF
            

>>XP_006721579 (OMIM: 201475,609575) PREDICTED: very lon  (662 aa)
 initn: 4109 init1: 3634 opt: 4103  Z-score: 4698.9  bits: 879.8 E(85289):    0
Smith-Waterman score: 4103; 96.1% identity (97.6% similar) in 662 aa overlap (1-655:1-662)

               10        20        30        40        50        60
pF1KB5 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL
              490       500       510       520       530       540

              550       560          570           580       590   
pF1KB5 EQFATVVEAKLIKHKKGIVNEQF---LLQRLADGA----IDLYAMVVVLSRASRSLSEGH
       :::::::::::::::::::.:.     :.: . :      ..:  ... .::::::::::
XP_006 EQFATVVEAKLIKHKKGIVSEEAGRECLSRRGPGPGSQPAQIYFHLLLPARASRSLSEGH
              550       560       570       580       590       600

           600       610       620       630       640       650   
pF1KB5 PTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPL
              610       620       630       640       650       660

         
pF1KB5 GF
       ::
XP_006 GF
         

>>NP_001029031 (OMIM: 201475,609575) very long-chain spe  (633 aa)
 initn: 3819 init1: 3819 opt: 3829  Z-score: 4385.3  bits: 821.7 E(85289):    0
Smith-Waterman score: 4065; 96.6% identity (96.6% similar) in 655 aa overlap (1-655:1-633)

               10        20        30        40        50        60
pF1KB5 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
       ::::::::::::::::::::::::::::::::::::::::::::::              
NP_001 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQ--------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB5 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------ESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
                 50        60        70        80        90        

              130       140       150       160       170       180
pF1KB5 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
      100       110       120       130       140       150        

              190       200       210       220       230       240
pF1KB5 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
      160       170       180       190       200       210        

              250       260       270       280       290       300
pF1KB5 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
      220       230       240       250       260       270        

              310       320       330       340       350       360
pF1KB5 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
      280       290       300       310       320       330        

              370       380       390       400       410       420
pF1KB5 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
      340       350       360       370       380       390        

              430       440       450       460       470       480
pF1KB5 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK
      400       410       420       430       440       450        

              490       500       510       520       530       540
pF1KB5 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL
      460       470       480       490       500       510        

              550       560       570       580       590       600
pF1KB5 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK
      520       530       540       550       560       570        

              610       620       630       640       650     
pF1KB5 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
      580       590       600       610       620       630   

>>NP_001257377 (OMIM: 201475,609575) very long-chain spe  (579 aa)
 initn: 3768 init1: 3768 opt: 3768  Z-score: 4316.0  bits: 808.7 E(85289):    0
Smith-Waterman score: 3768; 100.0% identity (100.0% similar) in 579 aa overlap (77-655:1-579)

         50        60        70        80        90       100      
pF1KB5 LALDKSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELV
                                     ::::::::::::::::::::::::::::::
NP_001                               MFKGQLTTDQVFPYPSVLNEEQTQFLKELV
                                             10        20        30

        110       120       130       140       150       160      
pF1KB5 EPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEI
               40        50        60        70        80        90

        170       180       190       200       210       220      
pF1KB5 VGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAA
              100       110       120       130       140       150

        230       240       250       260       270       280      
pF1KB5 SIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVER
              160       170       180       190       200       210

        290       300       310       320       330       340      
pF1KB5 GFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAA
              220       230       240       250       260       270

        350       360       370       380       390       400      
pF1KB5 ALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ
              280       290       300       310       320       330

        410       420       430       440       450       460      
pF1KB5 GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTND
              340       350       360       370       380       390

        470       480       490       500       510       520      
pF1KB5 ILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVH
              400       410       420       430       440       450

        530       540       550       560       570       580      
pF1KB5 PELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRAS
              460       470       480       490       500       510

        590       600       610       620       630       640      
pF1KB5 RSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGG
              520       530       540       550       560       570

        650     
pF1KB5 VVTSNPLGF
       :::::::::
NP_001 VVTSNPLGF
                

>>XP_011522132 (OMIM: 201475,609575) PREDICTED: very lon  (621 aa)
 initn: 3881 init1: 3120 opt: 3120  Z-score: 3573.2  bits: 671.4 E(85289): 2.7e-192
Smith-Waterman score: 3821; 92.1% identity (93.1% similar) in 655 aa overlap (1-655:1-621)

               10        20        30        40        50        60
pF1KB5 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_011 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMA-
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KB5 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL
                             :.::.. . .     :.           .:   :::::
XP_011 ----------------------GRAGQRPESQRTCPPGV-----------ESEWRAVRAL
                           480       490                  500      

              550       560       570       580       590       600
pF1KB5 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEK
        510       520       530       540       550       560      

              610       620       630       640       650     
pF1KB5 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
        570       580       590       600       610       620 

>>XP_011522131 (OMIM: 201475,609575) PREDICTED: very lon  (628 aa)
 initn: 3731 init1: 3120 opt: 3120  Z-score: 3573.1  bits: 671.4 E(85289): 2.8e-192
Smith-Waterman score: 3665; 88.2% identity (90.8% similar) in 662 aa overlap (1-655:1-628)

               10        20        30        40        50        60
pF1KB5 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_011 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMA-
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KB5 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRAL
                             :.::.. . .     :.           .:   :::::
XP_011 ----------------------GRAGQRPESQRTCPPGV-----------ESEWRAVRAL
                           480       490                  500      

              550       560          570           580       590   
pF1KB5 EQFATVVEAKLIKHKKGIVNEQF---LLQRLADGA----IDLYAMVVVLSRASRSLSEGH
       :::::::::::::::::::.:.     :.: . :      ..:  ... .::::::::::
XP_011 EQFATVVEAKLIKHKKGIVSEEAGRECLSRRGPGPGSQPAQIYFHLLLPARASRSLSEGH
        510       520       530       540       550       560      

           600       610       620       630       640       650   
pF1KB5 PTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPL
        570       580       590       600       610       620      

         
pF1KB5 GF
       ::
XP_011 GF
         

>>NP_054768 (OMIM: 611103,611126) acyl-CoA dehydrogenase  (621 aa)
 initn: 948 init1: 566 opt: 1697  Z-score: 1943.0  bits: 369.7 E(85289): 1.7e-101
Smith-Waterman score: 1697; 46.6% identity (75.0% similar) in 599 aa overlap (60-653:29-617)

      30        40        50        60        70        80         
pF1KB5 QPRPGPARRPYAGGAAQLALDKSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFP
                                     : : .:     ..::  .: :..   .:::
NP_054   MSGCGLFLRTTAAARACRGLVVSTANRRLLRTSP---PVRAFAKELFLGKIKKKEVFP
                 10        20        30           40        50     

      90       100       110       120       130       140         
pF1KB5 YPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSE
       .: : ..: .. ..... :: .:: :  :  : :    . . : . :: :: :::::: :
NP_054 FPEVSQDELNE-INQFLGPVEKFFTEEVDSRKIDQEGKIPDETLEKLKSLGLFGLQVPEE
          60         70        80        90       100       110    

     150       160       170       180       190       200         
pF1KB5 LGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGE
        ::.:. ::.:.:: ::..: : .. .::.:::.::.:::.: ::. :: ::::::::::
NP_054 YGGLGFSNTMYSRLGEIISM-DGSITVTLAAHQAIGLKGIILAGTEEQKAKYLPKLASGE
          120       130        140       150       160       170   

     210       220       230       240       250       260         
pF1KB5 TVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD
        .::::::::.:::::::::. :. :   :.: :::::.::.:::::.:::::::: :.:
NP_054 HIAAFCLTEPASGSDAASIRSRATLSEDKKHYILNGSKVWITNGGLANIFTVFAKTEVVD
           180       190       200       210       220       230   

     270       280       290       300       310       320         
pF1KB5 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSG
        . :.::.:::::.::: :::.:.: :: :.::..::: :: :.....: ::.:::::.:
NP_054 -SDGSVKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVHFENTKIPVENILGEVGDG
            240       250       260       270       280       290  

     330       340       350       360       370       380         
pF1KB5 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVML
       :::::.:::.:::.:....:: .. .:  ....: .: ::.... .:::::::.: :.. 
NP_054 FKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQFNKRLSEFGLIQEKFALMAQK
            300       310       320       330       340       350  

     390       400        410       420       430       440        
pF1KB5 QYVTESMAYMVSANMDQ-GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGV
        :: :::.:.... .:: :  : .::::. :.:.:::::. ..: .::.::.:. ..   
NP_054 AYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGLGYTRDYPY
            360       370       380       390       400       410  

      450       460       470       480       490       500        
pF1KB5 ERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQ
       ::.::: ::. ::::::.:::...:: : .  :. :.     ::.  .... ..  .:..
NP_054 ERILRDTRILLIFEGTNEILRMYIALTGLQHAGRILTTRIHELKQ--AKVSTVMDTVGRR
            420       430       440       450         460       470

      510       520          530       540       550       560     
pF1KB5 LRRRAGLGSGLSLSG---LVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLL
       ::   :    :.:.:   .::: :. :..   .    :. .::. :..  : :..::..:
NP_054 LRDSLGRTVDLGLTGNHGVVHPSLADSANKFEENTYCFGRTVETLLLRFGKTIMEEQLVL
              480       490       500       510       520       530

         570       580       590       600       610       620     
pF1KB5 QRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDP
       .:.:.  :.::.:..::::::::.  :  . .:: .: .:.:.::   ... ..  : : 
NP_054 KRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANTFCVEA--YLQNLFSLSQLDK
              540       550       560       570         580        

          630       640       650       
pF1KB5 WQQE-LYRNFKSISKALVERGGVVTSNPLGF  
       .  : : ...:..:. ..:. . . ..::    
NP_054 YAPENLDEQIKKVSQQILEKRAYICAHPLDRTC
      590       600       610       620 

>>XP_016861753 (OMIM: 611103,611126) PREDICTED: acyl-CoA  (537 aa)
 initn: 718 init1: 566 opt: 1410  Z-score: 1615.1  bits: 308.9 E(85289): 3.2e-83
Smith-Waterman score: 1410; 50.4% identity (78.1% similar) in 452 aa overlap (160-607:2-449)

     130       140       150       160       170       180         
pF1KB5 ETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGI
                                     :.:: ::..: : .. .::.:::.::.:::
XP_016                              MYSRLGEIISM-DGSITVTLAAHQAIGLKGI
                                            10         20        30

     190       200       210       220       230       240         
pF1KB5 LLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLW
       .: ::. :: :::::::::: .::::::::.:::::::::. :. :   :.: :::::.:
XP_016 ILAGTEEQKAKYLPKLASGEHIAAFCLTEPASGSDAASIRSRATLSEDKKHYILNGSKVW
               40        50        60        70        80        90

     250       260       270       280       290       300         
pF1KB5 ISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAE
       :.:::::.:::::::: :.: . :.::.:::::.::: :::.:.: :: :.::..::: :
XP_016 ITNGGLANIFTVFAKTEVVD-SDGSVKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCE
              100       110        120       130       140         

     310       320       330       340       350       360         
pF1KB5 VFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQF
       : :.....: ::.:::::.::::::.:::.:::.:....:: .. .:  ....: .: ::
XP_016 VHFENTKIPVENILGEVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQF
     150       160       170       180       190       200         

     370       380       390       400        410       420        
pF1KB5 GEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ-GATDFQIEAAISKIFGSEAAWK
       .... .:::::::.: :..  :: :::.:.... .:: :  : .::::. :.:.:::::.
XP_016 NKRLSEFGLIQEKFALMAQKAYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSSEAAWQ
     210       220       230       240       250       260         

      430       440       450       460       470       480        
pF1KB5 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG
        ..: .::.::.:. ..   ::.::: ::. ::::::.:::...:: : .  :. :.   
XP_016 CVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYIALTGLQHAGRILTTRI
     270       280       290       300       310       320         

      490       500       510       520          530       540     
pF1KB5 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSG---LVHPELSRSGELAVRALEQFAT
         ::.  .... ..  .:..::   :    :.:.:   .::: :. :..   .    :. 
XP_016 HELKQ--AKVSTVMDTVGRRLRDSLGRTVDLGLTGNHGVVHPSLADSANKFEENTYCFGR
     330         340       350       360       370       380       

         550       560       570       580       590       600     
pF1KB5 VVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDT
       .::. :..  : :..::..:.:.:.  :.::.:..::::::::.  :  . .::.    .
XP_016 TVETLLLRFGKTIMEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEQGTDPA
       390       400       410       420       430       440       

         610       620       630       640       650               
pF1KB5 WCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF          
        :                                                          
XP_016 HCPLCWREAGAVSEDPLYTRISACTFQSTCRYQDCDICLSEETGSEMLSHLLLGKGCWIR
       450       460       470       480       490       500       

>>XP_016877645 (OMIM: 243500,607036) PREDICTED: isovaler  (407 aa)
 initn: 708 init1: 261 opt: 724  Z-score: 830.9  bits: 163.4 E(85289): 1.5e-39
Smith-Waterman score: 724; 32.2% identity (68.4% similar) in 395 aa overlap (79-472:17-398)

       50        60        70        80         90       100       
pF1KB5 LDKSDSHPSDALTRKKPAKAESKSFAVGMFKG-QLTTDQVFPYPSVLNEEQTQFLKELVE
                                     :: : . ... :  . : . ...::.: . 
XP_016               MVFWWRIGQATYRLWHKGPQSVCSSLTPEQAELRQTMAKFLQEHLA
                             10        20        30        40      

       110       120       130       140       150       160       
pF1KB5 PVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIV
       : .   .:..   ... .. ..:  :. : .::..:. .: . :: ::   ... ..: .
XP_016 PKA---QEID---RSNEFKNLREF-WKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEI
            50           60         70        80        90         

       170       180       190       200       210       220       
pF1KB5 GMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAAS
       .  . .::.. :::... .. ..  :..:::::::::: ::: ..:. ..::..:::..:
XP_016 SRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVS
     100       110       120       130       140       150         

       230       240       250       260       270       280       
pF1KB5 IRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERG
       .. .:  .  :..: :::.:.::.::  ::.. :.:::   : :.  ... ::::.::.:
XP_016 MKLKAEKK--GNHYILNGNKFWITNGPDADVLIVYAKT---DLAAVPASRGITAFIVEKG
     160         170       180       190          200       210    

       290       300       310       320       330       340       
pF1KB5 FGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAA
       . :.. .    :.:...::: :..:.  ..:. :.::. ..:  : :  :.  :. .:..
XP_016 MPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGG
          220       230       240       250       260       270    

       350       360       370       380       390       400       
pF1KB5 LAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQG
         : :.... ... .   :  ::.:: .: :.: :.: :    .. ....: :.   :.:
XP_016 PLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEG
          280       290       300       310       320       330    

       410       420       430       440       450       460       
pF1KB5 ATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDI
           .  :..  ....: : .:. . :: .:: :....  . : ::: ....:  ::...
XP_016 HCTAKDCAGVI-LYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEV
          340        350       360       370       380       390   

       470       480       490       500       510       520       
pF1KB5 LRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHP
        :: .                                                       
XP_016 RRLVIGRAFNADFH                                              
           400                                                     




655 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:16:21 2016 done: Sat Nov  5 07:16:22 2016
 Total Scan time:  7.980 Total Display time:  0.110

Function used was FASTA [36.3.4 Apr, 2011]
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