Result of FASTA (omim) for pF1KB4374
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4374, 414 aa
  1>>>pF1KB4374 414 - 414 aa - 414 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3664+/-0.00035; mu= 11.5665+/- 0.022
 mean_var=83.2377+/-17.425, 0's: 0 Z-trim(116.3): 221  B-trim: 2132 in 2/51
 Lambda= 0.140577
 statistics sampled from 27040 (27318) to 27040 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.32), width:  16
 Scan time:  8.420

The best scores are:                                      opt bits E(85289)
NP_064525 (OMIM: 607815) ankyrin repeat and steril ( 414) 2812 580.0 3.6e-165
NP_001190999 (OMIM: 607815) ankyrin repeat and ste ( 426) 2657 548.6 1.1e-155
XP_016875154 (OMIM: 607815) PREDICTED: ankyrin rep ( 425) 2652 547.6 2.2e-155
XP_006719577 (OMIM: 607815) PREDICTED: ankyrin rep (1184) 2579 532.9 1.5e-150
XP_016875147 (OMIM: 607815) PREDICTED: ankyrin rep (1188) 2566 530.3 9.7e-150
NP_001190996 (OMIM: 607815) ankyrin repeat and ste ( 394) 2412 498.9 9.1e-141
XP_006719575 (OMIM: 607815) PREDICTED: ankyrin rep (1200) 2411 498.9 2.8e-140
XP_006719576 (OMIM: 607815) PREDICTED: ankyrin rep (1199) 2406 497.9 5.7e-140
NP_001191010 (OMIM: 607815) ankyrin repeat and ste ( 254) 1520 317.9 1.8e-86
NP_690001 (OMIM: 607815) ankyrin repeat and steril (1248) 1521 318.4 6.4e-86
XP_016875143 (OMIM: 607815) PREDICTED: ankyrin rep (1268) 1507 315.5 4.6e-85
XP_016875142 (OMIM: 607815) PREDICTED: ankyrin rep (1272) 1507 315.5 4.6e-85
XP_006719570 (OMIM: 607815) PREDICTED: ankyrin rep (1273) 1507 315.5 4.6e-85
XP_005269089 (OMIM: 607815) PREDICTED: ankyrin rep ( 266) 1365 286.5 5.3e-77
NP_001191009 (OMIM: 607815) ankyrin repeat and ste ( 266) 1365 286.5 5.3e-77
XP_016875153 (OMIM: 607815) PREDICTED: ankyrin rep ( 429) 1366 286.8 7.1e-77
XP_016875149 (OMIM: 607815) PREDICTED: ankyrin rep ( 486) 1366 286.8 7.9e-77
NP_001190997 (OMIM: 607815) ankyrin repeat and ste ( 460) 1361 285.8 1.5e-76
XP_005269086 (OMIM: 607815) PREDICTED: ankyrin rep (1256) 1366 286.9 1.9e-76
XP_005269085 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 1366 286.9 1.9e-76
XP_016875146 (OMIM: 607815) PREDICTED: ankyrin rep (1226) 1365 286.7 2.1e-76
XP_006719573 (OMIM: 607815) PREDICTED: ankyrin rep (1235) 1364 286.5 2.4e-76
NP_001190994 (OMIM: 607815) ankyrin repeat and ste ( 290) 1352 283.9 3.6e-76
XP_006719572 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 1361 285.9 3.8e-76
NP_001190998 (OMIM: 607815) ankyrin repeat and ste ( 450) 1352 283.9 5.3e-76
XP_016875152 (OMIM: 607815) PREDICTED: ankyrin rep ( 476) 1352 284.0 5.6e-76
XP_016875150 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 1352 284.0 5.6e-76
NP_858056 (OMIM: 607815) ankyrin repeat and steril ( 510) 1352 284.0 5.9e-76
XP_016875148 (OMIM: 607815) PREDICTED: ankyrin rep ( 511) 1352 284.0 5.9e-76
NP_001191008 (OMIM: 607815) ankyrin repeat and ste ( 290) 1347 282.9 7.2e-76
NP_001190995 (OMIM: 607815) ankyrin repeat and ste ( 357) 1347 282.9 8.7e-76
XP_016875151 (OMIM: 607815) PREDICTED: ankyrin rep ( 479) 1347 282.9 1.1e-75
XP_016875145 (OMIM: 607815) PREDICTED: ankyrin rep (1250) 1352 284.1 1.3e-75
XP_011536873 (OMIM: 607815) PREDICTED: ankyrin rep (1251) 1352 284.1 1.3e-75
XP_016875141 (OMIM: 607815) PREDICTED: ankyrin rep (1281) 1352 284.1 1.4e-75
XP_006719567 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 1352 284.1 1.4e-75
XP_016875140 (OMIM: 607815) PREDICTED: ankyrin rep (1285) 1352 284.1 1.4e-75
XP_016875144 (OMIM: 607815) PREDICTED: ankyrin rep (1259) 1350 283.7 1.8e-75
XP_006719571 (OMIM: 607815) PREDICTED: ankyrin rep (1260) 1350 283.7 1.8e-75
XP_006719569 (OMIM: 607815) PREDICTED: ankyrin rep (1283) 1347 283.1 2.7e-75
XP_006719568 (OMIM: 607815) PREDICTED: ankyrin rep (1284) 1347 283.1 2.7e-75
XP_016866082 (OMIM: 608994) PREDICTED: ankyrin rep ( 593)  655 142.6 2.4e-33
XP_011512739 (OMIM: 608994) PREDICTED: ankyrin rep ( 604)  655 142.6 2.5e-33
XP_011512738 (OMIM: 608994) PREDICTED: ankyrin rep (1100)  655 142.7 4.2e-33
NP_056060 (OMIM: 608994) ankyrin repeat and SAM do (1134)  655 142.7 4.3e-33
XP_011512737 (OMIM: 608994) PREDICTED: ankyrin rep (1144)  655 142.7 4.4e-33
XP_011512736 (OMIM: 608994) PREDICTED: ankyrin rep (1145)  655 142.7 4.4e-33
XP_005249021 (OMIM: 608994) PREDICTED: ankyrin rep (1155)  655 142.7 4.4e-33
XP_006715099 (OMIM: 608994) PREDICTED: ankyrin rep (1156)  655 142.7 4.4e-33
XP_011512735 (OMIM: 608994) PREDICTED: ankyrin rep (1162)  655 142.7 4.4e-33


>>NP_064525 (OMIM: 607815) ankyrin repeat and sterile al  (414 aa)
 initn: 2812 init1: 2812 opt: 2812  Z-score: 3086.3  bits: 580.0 E(85289): 3.6e-165
Smith-Waterman score: 2812; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414)

               10        20        30        40        50        60
pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
              310       320       330       340       350       360

              370       380       390       400       410    
pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
              370       380       390       400       410    

>>NP_001190999 (OMIM: 607815) ankyrin repeat and sterile  (426 aa)
 initn: 2736 init1: 2654 opt: 2657  Z-score: 2916.2  bits: 548.6 E(85289): 1.1e-155
Smith-Waterman score: 2657; 96.8% identity (98.0% similar) in 407 aa overlap (1-407:1-399)

               10        20        30        40        50        60
pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
              310       320       330       340       350       360

              370       380       390       400       410          
pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF      
       ::::::::::::::::::::::::::::::..        .:::..:             
NP_001 GGHSSTLPESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKTLANLPWIVEPGQE
              370       380       390               400       410  

NP_001 AKRGINTKYETTIF
            420      

>>XP_016875154 (OMIM: 607815) PREDICTED: ankyrin repeat   (425 aa)
 initn: 2652 init1: 2652 opt: 2652  Z-score: 2910.8  bits: 547.6 E(85289): 2.2e-155
Smith-Waterman score: 2652; 100.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390)

               10        20        30        40        50        60
pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
              310       320       330       340       350       360

              370       380       390       400       410          
pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF      
       ::::::::::::::::::::::::::::::                              
XP_016 GGHSSTLPESFENKPSKPIPKPRVSIRKSVIDPSEQKTLANLPWIVEPGQEAKRGINTKY
              370       380       390       400       410       420

>>XP_006719577 (OMIM: 607815) PREDICTED: ankyrin repeat   (1184 aa)
 initn: 2579 init1: 2579 opt: 2579  Z-score: 2823.6  bits: 532.9 E(85289): 1.5e-150
Smith-Waterman score: 2579; 99.0% identity (99.7% similar) in 387 aa overlap (28-414:798-1184)

                  10        20        30        40        50       
pF1KB4    MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHL
                                     :. ..:::::::::::::::::::::::::
XP_006 GNSERTPSFTSEWEEIDKIMSSIDVGINNELKEMNGPRCPVQTVGQWLESIGLPQYENHL
       770       780       790       800       810       820       

        60        70        80        90       100       110       
pF1KB4 MANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAE
       830       840       850       860       870       880       

       120       130       140       150       160       170       
pF1KB4 WLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDP
       890       900       910       920       930       940       

       180       190       200       210       220       230       
pF1KB4 PQKPPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQKPPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSML
       950       960       970       980       990      1000       

       240       250       260       270       280       290       
pF1KB4 IKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIR
      1010      1020      1030      1040      1050      1060       

       300       310       320       330       340       350       
pF1KB4 NISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ
      1070      1080      1090      1100      1110      1120       

       360       370       380       390       400       410    
pF1KB4 ARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
      1130      1140      1150      1160      1170      1180    

>>XP_016875147 (OMIM: 607815) PREDICTED: ankyrin repeat   (1188 aa)
 initn: 2566 init1: 2566 opt: 2566  Z-score: 2809.3  bits: 530.3 E(85289): 9.7e-150
Smith-Waterman score: 2566; 99.7% identity (99.7% similar) in 383 aa overlap (32-414:806-1188)

              10        20        30        40        50        60 
pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG
                                     : ::::::::::::::::::::::::::::
XP_016 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG
         780       790       800       810       820       830     

              70        80        90       100       110       120 
pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
         840       850       860       870       880       890     

             130       140       150       160       170       180 
pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
         900       910       920       930       940       950     

             190       200       210       220       230       240 
pF1KB4 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
         960       970       980       990      1000      1010     

             250       260       270       280       290       300 
pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
        1020      1030      1040      1050      1060      1070     

             310       320       330       340       350       360 
pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
        1080      1090      1100      1110      1120      1130     

             370       380       390       400       410    
pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
        1140      1150      1160      1170      1180        

>>NP_001190996 (OMIM: 607815) ankyrin repeat and sterile  (394 aa)
 initn: 2412 init1: 2412 opt: 2412  Z-score: 2648.2  bits: 498.9 E(85289): 9.1e-141
Smith-Waterman score: 2412; 100.0% identity (100.0% similar) in 358 aa overlap (33-390:2-359)

             10        20        30        40        50        60  
pF1KB4 WQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGF
                                     ::::::::::::::::::::::::::::::
NP_001                              MGPRCPVQTVGQWLESIGLPQYENHLMANGF
                                            10        20        30 

             70        80        90       100       110       120  
pF1KB4 DNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSI
              40        50        60        70        80        90 

            130       140       150       160       170       180  
pF1KB4 ELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPP
             100       110       120       130       140       150 

            190       200       210       220       230       240  
pF1KB4 RSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELR
             160       170       180       190       200       210 

            250       260       270       280       290       300  
pF1KB4 GTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCA
             220       230       240       250       260       270 

            310       320       330       340       350       360  
pF1KB4 AQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGG
             280       290       300       310       320       330 

            370       380       390       400       410            
pF1KB4 HSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF        
       ::::::::::::::::::::::::::::                                
NP_001 HSSTLPESFENKPSKPIPKPRVSIRKSVIDPSEQKTLANLPWIVEPGQEAKRGINTKYET
             340       350       360       370       380       390 

>>XP_006719575 (OMIM: 607815) PREDICTED: ankyrin repeat   (1200 aa)
 initn: 2488 init1: 2406 opt: 2411  Z-score: 2639.4  bits: 498.9 E(85289): 2.8e-140
Smith-Waterman score: 2411; 96.3% identity (97.6% similar) in 376 aa overlap (32-407:806-1173)

              10        20        30        40        50        60 
pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG
                                     : ::::::::::::::::::::::::::::
XP_006 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG
         780       790       800       810       820       830     

              70        80        90       100       110       120 
pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
         840       850       860       870       880       890     

             130       140       150       160       170       180 
pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
         900       910       920       930       940       950     

             190       200       210       220       230       240 
pF1KB4 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
         960       970       980       990      1000      1010     

             250       260       270       280       290       300 
pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
        1020      1030      1040      1050      1060      1070     

             310       320       330       340       350       360 
pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
        1080      1090      1100      1110      1120      1130     

             370       380       390       400       410           
pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF       
       :::::::::::::::::::::::::::::..        .:::..:              
XP_006 GHSSTLPESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKTLANLPWIVEPGQEA
        1140      1150      1160              1170      1180       

XP_006 KRGINTKYETTIF
      1190      1200

>>XP_006719576 (OMIM: 607815) PREDICTED: ankyrin repeat   (1199 aa)
 initn: 2406 init1: 2406 opt: 2406  Z-score: 2633.9  bits: 497.9 E(85289): 5.7e-140
Smith-Waterman score: 2406; 99.7% identity (99.7% similar) in 359 aa overlap (32-390:806-1164)

              10        20        30        40        50        60 
pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG
                                     : ::::::::::::::::::::::::::::
XP_006 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG
         780       790       800       810       820       830     

              70        80        90       100       110       120 
pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
         840       850       860       870       880       890     

             130       140       150       160       170       180 
pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
         900       910       920       930       940       950     

             190       200       210       220       230       240 
pF1KB4 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
         960       970       980       990      1000      1010     

             250       260       270       280       290       300 
pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
        1020      1030      1040      1050      1060      1070     

             310       320       330       340       350       360 
pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
        1080      1090      1100      1110      1120      1130     

             370       380       390       400       410           
pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF       
       :::::::::::::::::::::::::::::                               
XP_006 GHSSTLPESFENKPSKPIPKPRVSIRKSVIDPSEQKTLANLPWIVEPGQEAKRGINTKYE
        1140      1150      1160      1170      1180      1190     

>>NP_001191010 (OMIM: 607815) ankyrin repeat and sterile  (254 aa)
 initn: 1520 init1: 1520 opt: 1520  Z-score: 1673.6  bits: 317.9 E(85289): 1.8e-86
Smith-Waterman score: 1520; 95.4% identity (97.1% similar) in 240 aa overlap (175-414:15-254)

          150       160       170       180       190       200    
pF1KB4 IWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLRTGDWGEPSITLRPPNE
                                     :: :..  .    .::::::::::::::::
NP_001                 MQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEPSITLRPPNE
                               10        20        30        40    

          210       220       230       240       250       260    
pF1KB4 ATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQ
           50        60        70        80        90       100    

          270       280       290       300       310       320    
pF1KB4 MKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHH
          110       120       130       140       150       160    

          330       340       350       360       370       380    
pF1KB4 YCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRV
          170       180       190       200       210       220    

          390       400       410    
pF1KB4 SIRKSVDLLHASHTGQEPSERHTEEALRKF
       ::::::::::::::::::::::::::::::
NP_001 SIRKSVDLLHASHTGQEPSERHTEEALRKF
          230       240       250    

>>NP_690001 (OMIM: 607815) ankyrin repeat and sterile al  (1248 aa)
 initn: 1602 init1: 1520 opt: 1521  Z-score: 1663.6  bits: 318.4 E(85289): 6.4e-86
Smith-Waterman score: 2436; 86.2% identity (86.2% similar) in 443 aa overlap (32-414:806-1248)

              10        20        30        40        50        60 
pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG
                                     : ::::::::::::::::::::::::::::
NP_690 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG
         780       790       800       810       820       830     

              70        80        90       100       110       120 
pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS
         840       850       860       870       880       890     

             130       140       150       160       170       180 
pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP
         900       910       920       930       940       950     

                                                                   
pF1KB4 PRSITLR-----------------------------------------------------
       :::::::                                                     
NP_690 PRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSK
         960       970       980       990      1000      1010     

             190       200       210       220       230       240 
pF1KB4 -------TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LERQMAQTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL
        1020      1030      1040      1050      1060      1070     

             250       260       270       280       290       300 
pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC
        1080      1090      1100      1110      1120      1130     

             310       320       330       340       350       360 
pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG
        1140      1150      1160      1170      1180      1190     

             370       380       390       400       410    
pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
        1200      1210      1220      1230      1240        




414 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:49:03 2016 done: Sat Nov  5 05:49:05 2016
 Total Scan time:  8.420 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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