Result of FASTA (omim) for pF1KB4091
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4091, 480 aa
  1>>>pF1KB4091 480 - 480 aa - 480 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6421+/-0.000561; mu= 11.8702+/- 0.034
 mean_var=191.9235+/-38.836, 0's: 0 Z-trim(113.5): 333  B-trim: 414 in 1/52
 Lambda= 0.092578
 statistics sampled from 22431 (22820) to 22431 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.268), width:  16
 Scan time:  8.240

The best scores are:                                      opt bits E(85289)
NP_005702 (OMIM: 606018) EGF-like repeat and disco ( 480) 3439 472.8 9.2e-133
NP_001265571 (OMIM: 606018) EGF-like repeat and di ( 470) 2910 402.1 1.7e-111
NP_001297249 (OMIM: 602281) lactadherin isoform c  ( 379) 1348 193.4 9.4e-49
NP_005919 (OMIM: 602281) lactadherin isoform a pre ( 387) 1334 191.5 3.5e-48
NP_001297248 (OMIM: 602281) lactadherin isoform d  ( 343) 1228 177.3 5.9e-44
NP_001297250 (OMIM: 602281) lactadherin isoform e  ( 275) 1069 156.0 1.3e-37
NP_001108086 (OMIM: 602281) lactadherin isoform b  ( 335)  929 137.4 6.1e-32
XP_016856149 (OMIM: 188055,227400,600880,601367,61 (2087)  924 137.7   3e-31
NP_000121 (OMIM: 188055,227400,600880,601367,61230 (2224)  924 137.7 3.1e-31
NP_000123 (OMIM: 134500,300841,306700) coagulation (2351)  884 132.4 1.3e-29
XP_016877695 (OMIM: 602281) PREDICTED: lactadherin ( 243)  674 103.1   9e-22
NP_063916 (OMIM: 134500,300841,306700) coagulation ( 216)  625 96.5 7.8e-20
NP_001019800 (OMIM: 602069) neuropilin-1 isoform c ( 609)  539 85.6 4.2e-16
XP_011518058 (OMIM: 602069) PREDICTED: neuropilin- ( 628)  539 85.6 4.3e-16
NP_001019799 (OMIM: 602069) neuropilin-1 isoform b ( 644)  539 85.6 4.4e-16
XP_011518057 (OMIM: 602069) PREDICTED: neuropilin- ( 656)  539 85.6 4.4e-16
XP_006717589 (OMIM: 602069) PREDICTED: neuropilin- ( 663)  539 85.7 4.5e-16
XP_016872355 (OMIM: 602069) PREDICTED: neuropilin- ( 742)  539 85.7 4.8e-16
XP_006717588 (OMIM: 602069) PREDICTED: neuropilin- ( 888)  539 85.8 5.3e-16
XP_006717587 (OMIM: 602069) PREDICTED: neuropilin- ( 889)  539 85.8 5.3e-16
XP_016872354 (OMIM: 602069) PREDICTED: neuropilin- ( 899)  539 85.8 5.4e-16
NP_001316997 (OMIM: 602069) neuropilin-1 isoform f ( 906)  539 85.8 5.4e-16
XP_006717585 (OMIM: 602069) PREDICTED: neuropilin- ( 907)  539 85.8 5.4e-16
NP_001231902 (OMIM: 602069) neuropilin-1 isoform e ( 916)  539 85.8 5.4e-16
NP_001231901 (OMIM: 602069) neuropilin-1 isoform d ( 917)  539 85.8 5.4e-16
NP_003864 (OMIM: 602069) neuropilin-1 isoform a pr ( 923)  539 85.8 5.5e-16
XP_006717584 (OMIM: 602069) PREDICTED: neuropilin- ( 924)  539 85.8 5.5e-16
XP_011510721 (OMIM: 608698) PREDICTED: discoidin,  ( 699)  478 77.5 1.3e-13
NP_563615 (OMIM: 608698) discoidin, CUB and LCCL d ( 775)  478 77.6 1.4e-13
NP_957716 (OMIM: 602070) neuropilin-2 isoform 6 pr ( 555)  361 61.8 5.7e-09
XP_016860677 (OMIM: 602070) PREDICTED: neuropilin- ( 848)  361 62.0 7.4e-09
XP_016860676 (OMIM: 602070) PREDICTED: neuropilin- ( 853)  361 62.0 7.5e-09
XP_016860675 (OMIM: 602070) PREDICTED: neuropilin- ( 901)  361 62.1 7.7e-09
NP_957719 (OMIM: 602070) neuropilin-2 isoform 5 pr ( 901)  361 62.1 7.7e-09
NP_061004 (OMIM: 602070) neuropilin-2 isoform 4 pr ( 906)  361 62.1 7.7e-09
NP_958436 (OMIM: 602070) neuropilin-2 isoform 3 pr ( 909)  361 62.1 7.8e-09
XP_016860674 (OMIM: 602070) PREDICTED: neuropilin- ( 926)  361 62.1 7.8e-09
NP_003863 (OMIM: 602070) neuropilin-2 isoform 2 pr ( 926)  361 62.1 7.8e-09
XP_005246991 (OMIM: 602070) PREDICTED: neuropilin- ( 931)  361 62.1 7.9e-09
XP_005246990 (OMIM: 602070) PREDICTED: neuropilin- ( 931)  361 62.1 7.9e-09
NP_957718 (OMIM: 602070) neuropilin-2 isoform 1 pr ( 931)  361 62.1 7.9e-09
XP_011513464 (OMIM: 602981) PREDICTED: adipocyte e (1132)  348 60.4   3e-08
NP_001120 (OMIM: 602981) adipocyte enhancer-bindin (1158)  348 60.5   3e-08
NP_000321 (OMIM: 300839,312700) retinoschisin prec ( 224)  333 57.5 4.4e-08
NP_001171628 (OMIM: 609555) probable carboxypeptid ( 660)  333 58.1 8.5e-08
NP_062555 (OMIM: 609555) probable carboxypeptidase ( 734)  333 58.2 9.1e-08
XP_011516860 (OMIM: 219730,609720,616220) PREDICTE (1220)  328 57.8   2e-07
XP_011516859 (OMIM: 219730,609720,616220) PREDICTE (1220)  328 57.8   2e-07
XP_011516858 (OMIM: 219730,609720,616220) PREDICTE (1276)  328 57.8   2e-07
NP_775960 (OMIM: 219730,609720,616220) protein cru (1285)  328 57.8   2e-07


>>NP_005702 (OMIM: 606018) EGF-like repeat and discoidin  (480 aa)
 initn: 3439 init1: 3439 opt: 3439  Z-score: 2504.5  bits: 472.8 E(85289): 9.2e-133
Smith-Waterman score: 3439; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)

               10        20        30        40        50        60
pF1KB4 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 SVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 RALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 EYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 CRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 QGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 VYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
              430       440       450       460       470       480

>>NP_001265571 (OMIM: 606018) EGF-like repeat and discoi  (470 aa)
 initn: 2897 init1: 2897 opt: 2910  Z-score: 2122.7  bits: 402.1 E(85289): 1.7e-111
Smith-Waterman score: 3348; 97.9% identity (97.9% similar) in 480 aa overlap (1-480:1-470)

               10        20        30        40        50        60
pF1KB4 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 SVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI
       :::::          :::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVVEV----------GPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI
                         70        80        90       100       110

              130       140       150       160       170       180
pF1KB4 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTH
              120       130       140       150       160       170

              190       200       210       220       230       240
pF1KB4 RALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSP
              180       190       200       210       220       230

              250       260       270       280       290       300
pF1KB4 EYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQV
              240       250       260       270       280       290

              310       320       330       340       350       360
pF1KB4 CRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDK
              300       310       320       330       340       350

              370       380       390       400       410       420
pF1KB4 QGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWT
              360       370       380       390       400       410

              430       440       450       460       470       480
pF1KB4 VYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
              420       430       440       450       460       470

>>NP_001297249 (OMIM: 602281) lactadherin isoform c [Hom  (379 aa)
 initn: 1343 init1: 851 opt: 1348  Z-score: 996.3  bits: 193.4 E(85289): 9.4e-49
Smith-Waterman score: 1348; 51.1% identity (76.7% similar) in 378 aa overlap (108-476:5-379)

        80        90       100       110       120       130       
pF1KB4 CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICT--
                                     :.: : :   :. . :  .::.:::.:   
NP_001                           MWPFPEGGNTIPILHT-DICSKNPCHNGGLCEEI
                                         10         20        30   

               140       150       160       170       180         
pF1KB4 ------DLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKW
             :.  .:.: :   . : .:. ::  :::.:.: :.:.::.:::.. ...:::.:
NP_001 SQEVRGDVFPSYTCTCLKGYAGNHCETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHW
            40        50        60        70        80        90   

     190       200       210       220       230       240         
pF1KB4 YPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIA
        :  ::::. :..:::: . ::  ::::.:: :.: ::::.::::.:..: ::.:..:.:
NP_001 VPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVA
           100       110       120       130       140       150   

     250        260       270       280       290       300        
pF1KB4 YSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLR
       :: .:. .  .. :.  ....:  :: ..:. ..: :  :..::::::::  :.  ::::
NP_001 YSLNGHEFDFIHDVNKKHKEFV--GNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLR
           160       170         180       190       200       210 

      310       320       330       340       350       360        
pF1KB4 MELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWT
       .:::::::.::..:::.:.. : : :::::: ..: .. .:.:.:  :::::::. :::.
NP_001 FELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWV
             220       230       240       250       260       270 

      370       380       390       400       410       420        
pF1KB4 SGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQR
       .:   ..:::::::    .:::::::::..:: ::::.:::.:::::. .:: ::: .  
NP_001 AGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTG
             280       290       300       310       320       330 

      430       440       450       460       470       480
pF1KB4 KDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
       ..:.: ::.:: .:.::... :: ::..:::: .:..::.:: :::::    
NP_001 SSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC    
             340       350       360       370             

>>NP_005919 (OMIM: 602281) lactadherin isoform a preprop  (387 aa)
 initn: 1343 init1: 851 opt: 1334  Z-score: 986.1  bits: 191.5 E(85289): 3.5e-48
Smith-Waterman score: 1339; 49.4% identity (72.6% similar) in 401 aa overlap (78-476:27-387)

        50        60        70        80        90        100      
pF1KB4 CECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCE-ISEAYRGDTFIGYVCK
                                     :. ::::::: :: ::.  :::.: .:.: 
NP_005     MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCT
                   10        20        30        40        50      

        110       120       130       140       150       160      
pF1KB4 CPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEG
       : .:. : ::.                                       ::  :::.:.
NP_005 CLKGYAGNHCET--------------------------------------KCVEPLGLEN
         60                                              70        

        170       180       190       200       210       220      
pF1KB4 GIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRV
       : :.:.::.:::.. ...:::.: :  ::::. :..:::: . ::  ::::.:: :.: :
NP_005 GNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWV
       80        90       100       110       120       130        

        230       240       250        260       270       280     
pF1KB4 TGVITQGAKRIGSPEYIKSYKIAYSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSF
       :::.::::.:..: ::.:..:.::: .:. .  .. :.  ....:  :: ..:. ..: :
NP_005 TGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFV--GNWNKNAVHVNLF
      140       150       160       170       180         190      

         290       300       310       320       330       340     
pF1KB4 TPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLN
         :..::::::::  :.  ::::.:::::::.::..:::.:.. : : :::::: ..: .
NP_005 ETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWG
        200       210       220       230       240       250      

         350       360       370       380       390       400     
pF1KB4 MDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFV
       . .:.:.:  :::::::. :::..:   ..:::::::    .:::::::::..:: ::::
NP_005 LHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFV
        260       270       280       290       300       310      

         410       420       430       440       450       460     
pF1KB4 GSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYG
       .:::.:::::. .:: ::: .  ..:.: ::.:: .:.::... :: ::..:::: .:..
NP_005 ASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHN
        320       330       340       350       360       370      

         470       480
pF1KB4 RITLRSELLGCTEEE
       ::.:: :::::    
NP_005 RIALRLELLGC    
        380           

>>NP_001297248 (OMIM: 602281) lactadherin isoform d prec  (343 aa)
 initn: 1224 init1: 851 opt: 1228  Z-score: 910.1  bits: 177.3 E(85289): 5.9e-44
Smith-Waterman score: 1228; 54.2% identity (80.7% similar) in 321 aa overlap (157-476:25-343)

        130       140       150       160       170       180      
pF1KB4 PCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGL
                                     .:  :::.:.: :.:.::.:::.. ...::
NP_001       MPRPRLLAALCGALLCAPSLLVALECVEPLGLENGNIANSQIAASSVRVTFLGL
                     10        20        30        40        50    

        190       200       210       220       230       240      
pF1KB4 QKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSY
       :.: :  ::::. :..:::: . ::  ::::.:: :.: ::::.::::.:..: ::.:..
NP_001 QHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAF
           60        70        80        90       100       110    

        250        260       270       280       290       300     
pF1KB4 KIAYSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHC
       :.::: .:. .  .. :.  ...  : :: ..:. ..: :  :..::::::::  :.  :
NP_001 KVAYSLNGHEFDFIHDVNKKHKE--FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTAC
          120       130         140       150       160       170  

         310       320       330       340       350       360     
pF1KB4 TLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVN
       :::.:::::::.::..:::.:.. : : :::::: ..: .. .:.:.:  :::::::. :
NP_001 TLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFN
            180       190       200       210       220       230  

         370       380       390       400       410       420     
pF1KB4 AWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDE
       ::..:   ..:::::::    .:::::::::..:: ::::.:::.:::::. .:: ::: 
NP_001 AWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDP
            240       250       260       270       280       290  

         430       440       450       460       470       480
pF1KB4 KQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
       .  ..:.: ::.:: .:.::... :: ::..:::: .:..::.:: :::::    
NP_001 RTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC    
            300       310       320       330       340       

>>NP_001297250 (OMIM: 602281) lactadherin isoform e [Hom  (275 aa)
 initn: 1074 init1: 851 opt: 1069  Z-score: 796.4  bits: 156.0 E(85289): 1.3e-37
Smith-Waterman score: 1069; 54.5% identity (80.9% similar) in 277 aa overlap (201-476:1-275)

              180       190       200       210       220       230
pF1KB4 NQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVI
                                     ..:::: . ::  ::::.:: :.: ::::.
NP_001                               MVNAWTPSSNDDNPWIQVNLLRRMWVTGVV
                                             10        20        30

              240       250        260       270       280         
pF1KB4 TQGAKRIGSPEYIKSYKIAYSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSFTPPI
       ::::.:..: ::.:..:.::: .:. .  .. :.  ....:  :: ..:. ..: :  :.
NP_001 TQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFV--GNWNKNAVHVNLFETPV
               40        50        60        70          80        

     290       300       310       320       330       340         
pF1KB4 KAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMF
       .::::::::  :.  ::::.:::::::.::..:::.:.. : : :::::: ..: .. .:
NP_001 EAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLF
       90       100       110       120       130       140        

     350       360       370       380       390       400         
pF1KB4 TWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYK
       .:.:  :::::::. :::..:   ..:::::::    .:::::::::..:: ::::.:::
NP_001 SWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYK
      150       160       170       180       190       200        

     410       420       430       440       450       460         
pF1KB4 LAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITL
       .:::::. .:: ::: .  ..:.: ::.:: .:.::... :: ::..:::: .:..::.:
NP_001 VAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIAL
      210       220       230       240       250       260        

     470       480
pF1KB4 RSELLGCTEEE
       : :::::    
NP_001 RLELLGC    
      270         

>>NP_001108086 (OMIM: 602281) lactadherin isoform b prec  (335 aa)
 initn: 933 init1: 441 opt: 929  Z-score: 694.4  bits: 137.4 E(85289): 6.1e-32
Smith-Waterman score: 1019; 41.4% identity (62.1% similar) in 401 aa overlap (78-476:27-335)

        50        60        70        80        90        100      
pF1KB4 CECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCE-ISEAYRGDTFIGYVCK
                                     :. ::::::: :: ::.  :::.: .:.: 
NP_001     MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCT
                   10        20        30        40        50      

        110       120       130       140       150       160      
pF1KB4 CPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEG
       : .:. : ::.                                       ::  :::.:.
NP_001 CLKGYAGNHCET--------------------------------------KCVEPLGLEN
         60                                              70        

        170       180       190       200       210       220      
pF1KB4 GIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRV
       : :.:.::.:::.. ...:::.: :  ::::. :..:::: . ::  ::::.:: :.: :
NP_001 GNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWV
       80        90       100       110       120       130        

        230       240       250        260       270       280     
pF1KB4 TGVITQGAKRIGSPEYIKSYKIAYSNDGKTWA-MYKVKGTNEDMVFRGNIDNNTPYANSF
       :::.::::.:..: ::.:..:.::: .:. .  .. :.  ....:  :: ..:. ..: :
NP_001 TGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFV--GNWNKNAVHVNLF
      140       150       160       170       180         190      

         290       300       310       320       330       340     
pF1KB4 TPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLN
         :..::::::::  :.  ::::.:::::::.::..:::.:.. : : :::::: ..: .
NP_001 ETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWG
        200       210       220       230       240       250      

         350       360       370       380       390       400     
pF1KB4 MDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFV
       . .:.:.:  :::::::. :::..:   ..::::.                         
NP_001 LHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQI-------------------------
        260       270       280       290                          

         410       420       430       440       450       460     
pF1KB4 GSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYG
                                  : ::.:: .:.::... :: ::..:::: .:..
NP_001 ---------------------------FPGNWDNHSHKKNLFETPILARYVRILPVAWHN
                                        300       310       320    

         470       480
pF1KB4 RITLRSELLGCTEEE
       ::.:: :::::    
NP_001 RIALRLELLGC    
          330         

>>XP_016856149 (OMIM: 188055,227400,600880,601367,612309  (2087 aa)
 initn: 934 init1: 420 opt: 924  Z-score: 682.0  bits: 137.7 E(85289): 3e-31
Smith-Waterman score: 924; 43.0% identity (68.2% similar) in 337 aa overlap (144-476:1760-2084)

           120       130       140       150       160       170   
pF1KB4 IHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQ
                                     . :  .: :.:..    :.:.  ::::..:
XP_016 GSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRM----PMGLSTGIISDSQ
    1730      1740      1750      1760      1770          1780     

           180       190       200           210       220         
pF1KB4 ITASSTHRALFGLQKWYPYYARLNKKGLINAWT----AAENDRWPWIQINLQRKMRVTGV
       : ::      : :  : :  ::::. :  :::.    :::    ::::...:... .::.
XP_016 IKASE-----F-LGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGI
        1790            1800      1810      1820      1830         

     230       240       250       260       270       280         
pF1KB4 ITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPI
        :::::.  .  :   . .:::..  .: ..: ..: . : : :: : .:   :.: :::
XP_016 QTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPI
    1840      1850      1860      1870      1880      1890         

     290       300       310       320       330       340         
pF1KB4 KAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMF
        :.:.:. :     . :::.:: :::..::: ::::..:.:.. ::::::. ..   :. 
XP_016 VARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDY-
    1900      1910      1920      1930      1940      1950         

     350       360       370       380       390       400         
pF1KB4 TWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYK
        ::: .:::. ::.:::: .  :...:::..:::   :.:.::::: :...  ..: :: 
XP_016 -WEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYT
      1960      1970      1980      1990      2000      2010       

     410       420       430       440       450       460         
pF1KB4 LAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITL
       . ::..: .:  :. ...  ::.:.:: ..  : :: ..::: .: ::..: .:   :.:
XP_016 IHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIAL
      2020      2030      2040      2050      2060      2070       

     470       480
pF1KB4 RSELLGCTEEE
       : ::.::    
XP_016 RLELFGCDIY 
      2080        

>>NP_000121 (OMIM: 188055,227400,600880,601367,612309,61  (2224 aa)
 initn: 934 init1: 420 opt: 924  Z-score: 681.7  bits: 137.7 E(85289): 3.1e-31
Smith-Waterman score: 924; 43.0% identity (68.2% similar) in 337 aa overlap (144-476:1897-2221)

           120       130       140       150       160       170   
pF1KB4 IHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQ
                                     . :  .: :.:..    :.:.  ::::..:
NP_000 GSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMDRDCRM----PMGLSTGIISDSQ
       1870      1880      1890      1900          1910      1920  

           180       190       200           210       220         
pF1KB4 ITASSTHRALFGLQKWYPYYARLNKKGLINAWT----AAENDRWPWIQINLQRKMRVTGV
       : ::      : :  : :  ::::. :  :::.    :::    ::::...:... .::.
NP_000 IKASE-----F-LGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGI
                 1930      1940      1950      1960      1970      

     230       240       250       260       270       280         
pF1KB4 ITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPI
        :::::.  .  :   . .:::..  .: ..: ..: . : : :: : .:   :.: :::
NP_000 QTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPI
       1980      1990      2000      2010      2020      2030      

     290       300       310       320       330       340         
pF1KB4 KAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMF
        :.:.:. :     . :::.:: :::..::: ::::..:.:.. ::::::. ..   :. 
NP_000 VARYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDY-
       2040      2050      2060      2070      2080      2090      

     350       360       370       380       390       400         
pF1KB4 TWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYK
        ::: .:::. ::.:::: .  :...:::..:::   :.:.::::: :...  ..: :: 
NP_000 -WEPFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYT
         2100      2110      2120      2130      2140      2150    

     410       420       430       440       450       460         
pF1KB4 LAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITL
       . ::..: .:  :. ...  ::.:.:: ..  : :: ..::: .: ::..: .:   :.:
NP_000 IHYSEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIAL
         2160      2170      2180      2190      2200      2210    

     470       480
pF1KB4 RSELLGCTEEE
       : ::.::    
NP_000 RLELFGCDIY 
         2220     

>>NP_000123 (OMIM: 134500,300841,306700) coagulation fac  (2351 aa)
 initn: 769 init1: 399 opt: 884  Z-score: 652.6  bits: 132.4 E(85289): 1.3e-29
Smith-Waterman score: 884; 44.9% identity (67.4% similar) in 325 aa overlap (157-480:2039-2349)

        130       140       150       160       170       180      
pF1KB4 PCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGL
                                     ::. :::. .: : . :::::.     .: 
NP_000 PSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQTPLGMASGHIRDFQITASGQ----YG-
     2010      2020      2030      2040      2050      2060        

        190       200       210       220       230       240      
pF1KB4 QKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSY
        .: :  :::. .: ::::.. :   . ::...:   : . :. ::::..  :  ::...
NP_000 -QWAPKLARLHYSGSINAWSTKEP--FSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQF
           2070      2080        2090      2100      2110      2120

        250       260       270       280       290       300      
pF1KB4 KIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCT
        : :: ::: :  :. ..:.  ::: ::.:..    : :.::: :.:.::.:     . :
NP_000 IIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST
             2130      2140      2150      2160      2170      2180

        310       320       330       340        350       360     
pF1KB4 LRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMF-TWEPRKARLDKQGKVN
       :::::.::.:..:: ::::.:  :.: :::::: :     .:: :: : ::::  ::. :
NP_000 LRMELMGCDLNSCSMPLGMESKAISDAQITASSYFT----NMFATWSPSKARLHLQGRSN
             2190      2200      2210          2220      2230      

         370       380       390       400       410       420     
pF1KB4 AWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDE
       ::    :. ..:::::.    ::::. :::.:..   ..:  . .. :.::..::..   
NP_000 AWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLF--F
       2240      2250      2260      2270      2280      2290      

         430       440       450       460       470       480  
pF1KB4 KQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE  
       .. : :::::: :. :   : .:::. .:..:: : ::  .:.:: :.:::  ..  
NP_000 QNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY
         2300      2310      2320      2330      2340      2350 




480 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:36:49 2016 done: Sat Nov  5 05:36:50 2016
 Total Scan time:  8.240 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com