Result of FASTA (omim) for pF1KB3799
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3799, 485 aa
  1>>>pF1KB3799 485 - 485 aa - 485 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8193+/-0.000404; mu= 16.3287+/- 0.025
 mean_var=118.9052+/-25.424, 0's: 0 Z-trim(113.9): 199  B-trim: 1347 in 1/56
 Lambda= 0.117618
 statistics sampled from 23190 (23435) to 23190 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.275), width:  16
 Scan time:  9.160

The best scores are:                                      opt bits E(85289)
XP_006724602 (OMIM: 300512) PREDICTED: WD repeat-c ( 485) 3242 561.8 1.5e-159
XP_011542249 (OMIM: 300512) PREDICTED: WD repeat-c ( 485) 3242 561.8 1.5e-159
NP_060353 (OMIM: 300512) WD repeat-containing prot ( 485) 3242 561.8 1.5e-159
XP_006724604 (OMIM: 300512) PREDICTED: WD repeat-c ( 393) 2633 458.4 1.7e-128
NP_001159898 (OMIM: 300512) WD repeat-containing p ( 393) 2633 458.4 1.7e-128
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  270 57.3 7.7e-08
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  270 57.3 7.7e-08
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  270 57.3 7.7e-08
NP_056975 (OMIM: 605585) pre-mRNA-processing facto ( 579)  210 47.4 0.00013
NP_001128304 (OMIM: 608629,608894) jouberin isofor (1053)  201 46.1 0.00057
XP_016866473 (OMIM: 608629,608894) PREDICTED: joub (1053)  201 46.1 0.00057
XP_016866472 (OMIM: 608629,608894) PREDICTED: joub (1064)  201 46.1 0.00057
XP_016866471 (OMIM: 608629,608894) PREDICTED: joub (1168)  201 46.2 0.00061
XP_016866470 (OMIM: 608629,608894) PREDICTED: joub (1178)  201 46.2 0.00061
XP_016866469 (OMIM: 608629,608894) PREDICTED: joub (1179)  201 46.2 0.00061
XP_016866467 (OMIM: 608629,608894) PREDICTED: joub (1186)  201 46.2 0.00062
XP_016866468 (OMIM: 608629,608894) PREDICTED: joub (1186)  201 46.2 0.00062
NP_001128302 (OMIM: 608629,608894) jouberin isofor (1196)  201 46.2 0.00062
XP_011534213 (OMIM: 608629,608894) PREDICTED: joub (1196)  201 46.2 0.00062
XP_011534212 (OMIM: 608629,608894) PREDICTED: joub (1196)  201 46.2 0.00062
XP_016866466 (OMIM: 608629,608894) PREDICTED: joub (1196)  201 46.2 0.00062
NP_001128303 (OMIM: 608629,608894) jouberin isofor (1196)  201 46.2 0.00062
NP_060121 (OMIM: 608629,608894) jouberin isoform a (1196)  201 46.2 0.00062
XP_016878126 (OMIM: 609540) PREDICTED: WD repeat-c ( 270)  185 42.8  0.0015
XP_011520396 (OMIM: 609540) PREDICTED: WD repeat-c ( 305)  185 42.8  0.0016
NP_001290176 (OMIM: 609540) WD repeat-containing p ( 305)  185 42.8  0.0016
NP_079510 (OMIM: 609540) WD repeat-containing prot ( 305)  185 42.8  0.0016
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540)  188 43.6  0.0017
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589)  188 43.7  0.0018
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627)  188 43.7  0.0018
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  188 43.7  0.0019
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  188 43.7  0.0019
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  188 43.7   0.002
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  188 43.7   0.002
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707)  188 43.7   0.002
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  188 43.7   0.002
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  188 43.7   0.002


>>XP_006724602 (OMIM: 300512) PREDICTED: WD repeat-conta  (485 aa)
 initn: 3242 init1: 3242 opt: 3242  Z-score: 2985.2  bits: 561.8 E(85289): 1.5e-159
Smith-Waterman score: 3242; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485)

               10        20        30        40        50        60
pF1KB3 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
              430       440       450       460       470       480

            
pF1KB3 RREQK
       :::::
XP_006 RREQK
            

>>XP_011542249 (OMIM: 300512) PREDICTED: WD repeat-conta  (485 aa)
 initn: 3242 init1: 3242 opt: 3242  Z-score: 2985.2  bits: 561.8 E(85289): 1.5e-159
Smith-Waterman score: 3242; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485)

               10        20        30        40        50        60
pF1KB3 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
              430       440       450       460       470       480

            
pF1KB3 RREQK
       :::::
XP_011 RREQK
            

>>NP_060353 (OMIM: 300512) WD repeat-containing protein   (485 aa)
 initn: 3242 init1: 3242 opt: 3242  Z-score: 2985.2  bits: 561.8 E(85289): 1.5e-159
Smith-Waterman score: 3242; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485)

               10        20        30        40        50        60
pF1KB3 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDAT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISAR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW
              430       440       450       460       470       480

            
pF1KB3 RREQK
       :::::
NP_060 RREQK
            

>>XP_006724604 (OMIM: 300512) PREDICTED: WD repeat-conta  (393 aa)
 initn: 2633 init1: 2633 opt: 2633  Z-score: 2427.8  bits: 458.4 E(85289): 1.7e-128
Smith-Waterman score: 2633; 100.0% identity (100.0% similar) in 393 aa overlap (93-485:1-393)

             70        80        90       100       110       120  
pF1KB3 GQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQ
                                     ::::::::::::::::::::::::::::::
XP_006                               MEDFEDDPRALGARGHRRSVSRGSYQLQAQ
                                             10        20        30

            130       140       150       160       170       180  
pF1KB3 MNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFAN
               40        50        60        70        80        90

            190       200       210       220       230       240  
pF1KB3 DDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMR
              100       110       120       130       140       150

            250       260       270       280       290       300  
pF1KB3 IWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSK
              160       170       180       190       200       210

            310       320       330       340       350       360  
pF1KB3 LTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSW
              220       230       240       250       260       270

            370       380       390       400       410       420  
pF1KB3 VSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGA
              280       290       300       310       320       330

            430       440       450       460       470       480  
pF1KB3 CVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRR
              340       350       360       370       380       390

          
pF1KB3 EQK
       :::
XP_006 EQK
          

>>NP_001159898 (OMIM: 300512) WD repeat-containing prote  (393 aa)
 initn: 2633 init1: 2633 opt: 2633  Z-score: 2427.8  bits: 458.4 E(85289): 1.7e-128
Smith-Waterman score: 2633; 100.0% identity (100.0% similar) in 393 aa overlap (93-485:1-393)

             70        80        90       100       110       120  
pF1KB3 GQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MEDFEDDPRALGARGHRRSVSRGSYQLQAQ
                                             10        20        30

            130       140       150       160       170       180  
pF1KB3 MNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFAN
               40        50        60        70        80        90

            190       200       210       220       230       240  
pF1KB3 DDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMR
              100       110       120       130       140       150

            250       260       270       280       290       300  
pF1KB3 IWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSK
              160       170       180       190       200       210

            310       320       330       340       350       360  
pF1KB3 LTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSW
              220       230       240       250       260       270

            370       380       390       400       410       420  
pF1KB3 VSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGA
              280       290       300       310       320       330

            430       440       450       460       470       480  
pF1KB3 CVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRR
              340       350       360       370       380       390

          
pF1KB3 EQK
       :::
NP_001 EQK
          

>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta  (334 aa)
 initn: 337 init1: 123 opt: 270  Z-score: 261.7  bits: 57.3 E(85289): 7.7e-08
Smith-Waterman score: 342; 26.0% identity (57.7% similar) in 350 aa overlap (138-483:19-333)

       110       120       130       140       150       160       
pF1KB3 HRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVF
                                     :.:.:  :.     : .. :::   .  ..
XP_005             MATEEKKPETEAARAQPTPSSSATQSKP----TPVKPNYA---LKFTL
                           10        20            30           40 

       170       180       190       200       210       220       
pF1KB3 DQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSL
         :. .::  :.:. . .  ::  : :  :..     .     ... ::  :.:: ::: 
XP_005 AGHT-KAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGK--FEKTISGHKLGISDVAWSS
               50         60        70          80        90       

       230       240       250       260       270       280       
pF1KB3 SNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHV
       ....:::.: : :..::   .:.:.. .    :  ..::.:.: ..:: : :.  ..:..
XP_005 DSNLLVSASDDKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFNP-QSNLIVSGSFDESVRI
       100       110       120        130        140       150     

       290       300       310       320       330       340       
pF1KB3 MNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLV
        ...::: .:   .. .  : :. :.  : :. ...  :  .  ..: :.:.  :.  :.
XP_005 WDVKTGKCLKTLPAH-SDPVSAVHFNRDGSLIVSSSYDG--LCRIWDTASGQCLKT--LI
         160       170        180       190         200         210

       350       360       370       380       390       400       
pF1KB3 VHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHP
         .. ::. .       . . . . .. : :.. :  .. :      ::       ..: 
XP_005 DDDNPPVSFV-------KFSPNGKYILAATLDNTL--KLWDYSKGKCLK-----TYTGHK
              220              230         240       250           

       410         420       430       440       450       460     
pF1KB3 VRSIFCPLMSFR--QGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDE
        .. .: . .:    :  .:.::::  :......  .:  :.:::::.  :.... .  :
XP_005 NEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQ--TKEIVQKLQGHTDVVISTACHPTE
         260       270       280         290       300       310   

         470         480     
pF1KB3 SLLASS--DASGMVIVWRREQK
       ...::.  . .  . .:. .  
XP_005 NIIASAALENDKTIKLWKSDC 
           320       330     

>>NP_438172 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 337 init1: 123 opt: 270  Z-score: 261.7  bits: 57.3 E(85289): 7.7e-08
Smith-Waterman score: 342; 26.0% identity (57.7% similar) in 350 aa overlap (138-483:19-333)

       110       120       130       140       150       160       
pF1KB3 HRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVF
                                     :.:.:  :.     : .. :::   .  ..
NP_438             MATEEKKPETEAARAQPTPSSSATQSKP----TPVKPNYA---LKFTL
                           10        20            30           40 

       170       180       190       200       210       220       
pF1KB3 DQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSL
         :. .::  :.:. . .  ::  : :  :..     .     ... ::  :.:: ::: 
NP_438 AGHT-KAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGK--FEKTISGHKLGISDVAWSS
               50         60        70          80        90       

       230       240       250       260       270       280       
pF1KB3 SNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHV
       ....:::.: : :..::   .:.:.. .    :  ..::.:.: ..:: : :.  ..:..
NP_438 DSNLLVSASDDKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFNP-QSNLIVSGSFDESVRI
       100       110       120        130        140       150     

       290       300       310       320       330       340       
pF1KB3 MNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLV
        ...::: .:   .. .  : :. :.  : :. ...  :  .  ..: :.:.  :.  :.
NP_438 WDVKTGKCLKTLPAH-SDPVSAVHFNRDGSLIVSSSYDG--LCRIWDTASGQCLKT--LI
         160       170        180       190         200         210

       350       360       370       380       390       400       
pF1KB3 VHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHP
         .. ::. .       . . . . .. : :.. :  .. :      ::       ..: 
NP_438 DDDNPPVSFV-------KFSPNGKYILAATLDNTL--KLWDYSKGKCLK-----TYTGHK
              220              230         240       250           

       410         420       430       440       450       460     
pF1KB3 VRSIFCPLMSFR--QGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDE
        .. .: . .:    :  .:.::::  :......  .:  :.:::::.  :.... .  :
NP_438 NEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQ--TKEIVQKLQGHTDVVISTACHPTE
         260       270       280         290       300       310   

         470         480     
pF1KB3 SLLASS--DASGMVIVWRREQK
       ...::.  . .  . .:. .  
NP_438 NIIASAALENDKTIKLWKSDC 
           320       330     

>>NP_060058 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 337 init1: 123 opt: 270  Z-score: 261.7  bits: 57.3 E(85289): 7.7e-08
Smith-Waterman score: 342; 26.0% identity (57.7% similar) in 350 aa overlap (138-483:19-333)

       110       120       130       140       150       160       
pF1KB3 HRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVF
                                     :.:.:  :.     : .. :::   .  ..
NP_060             MATEEKKPETEAARAQPTPSSSATQSKP----TPVKPNYA---LKFTL
                           10        20            30           40 

       170       180       190       200       210       220       
pF1KB3 DQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSL
         :. .::  :.:. . .  ::  : :  :..     .     ... ::  :.:: ::: 
NP_060 AGHT-KAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGK--FEKTISGHKLGISDVAWSS
               50         60        70          80        90       

       230       240       250       260       270       280       
pF1KB3 SNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHV
       ....:::.: : :..::   .:.:.. .    :  ..::.:.: ..:: : :.  ..:..
NP_060 DSNLLVSASDDKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFNP-QSNLIVSGSFDESVRI
       100       110       120        130        140       150     

       290       300       310       320       330       340       
pF1KB3 MNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLV
        ...::: .:   .. .  : :. :.  : :. ...  :  .  ..: :.:.  :.  :.
NP_060 WDVKTGKCLKTLPAH-SDPVSAVHFNRDGSLIVSSSYDG--LCRIWDTASGQCLKT--LI
         160       170        180       190         200         210

       350       360       370       380       390       400       
pF1KB3 VHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHP
         .. ::. .       . . . . .. : :.. :  .. :      ::       ..: 
NP_060 DDDNPPVSFV-------KFSPNGKYILAATLDNTL--KLWDYSKGKCLK-----TYTGHK
              220              230         240       250           

       410         420       430       440       450       460     
pF1KB3 VRSIFCPLMSFR--QGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDE
        .. .: . .:    :  .:.::::  :......  .:  :.:::::.  :.... .  :
NP_060 NEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQ--TKEIVQKLQGHTDVVISTACHPTE
         260       270       280         290       300       310   

         470         480     
pF1KB3 SLLASS--DASGMVIVWRREQK
       ...::.  . .  . .:. .  
NP_060 NIIASAALENDKTIKLWKSDC 
           320       330     

>>NP_056975 (OMIM: 605585) pre-mRNA-processing factor 17  (579 aa)
 initn: 107 init1: 107 opt: 210  Z-score: 203.7  bits: 47.4 E(85289): 0.00013
Smith-Waterman score: 214; 21.9% identity (55.3% similar) in 320 aa overlap (165-480:282-578)

          140       150       160       170       180       190    
pF1KB3 SVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRHRLACCSLD
                                     ::.. :. ..:  ::.   . : :  ::.:
NP_056 RSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHT-KGVSAVRLFPLSGHLLLSCSMD
             260       270       280        290       300       310

          200       210       220       230       240       250    
pF1KB3 GSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIRE
        .:.: . : .    ::.. ::...: :. .. ..  ..:.. :  ...: .: :.:: .
NP_056 CKIKLWE-VYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISR
               320       330       340       350       360         

          260       270         280       290       300       310  
pF1KB3 IPDPDSAELLCCTFQPVNN--NLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGRVLALSF
       . .       :  :.: ..  :: :.: . ...   .: .:. :.  . .: : : .. :
NP_056 FTNRKVP--YCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHL-GAVNTIVF
     370         380       390       400       410        420      

             320       330       340       350       360       370 
pF1KB3 -DAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSWVSREARDPS
        :   :.. ..::. :.  . .:. .  .    .  .:    ::     .:.. .. : .
NP_056 VDENRRFVSTSDDK-SLRVWEWDIPVD-FKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQ
        430       440        450        460       470       480    

             380       390       400       410       420       430 
pF1KB3 LLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGACVVTGSEDM
       .:: .  :.. : .    .: .    .  ..         : : ::.     :..:. . 
NP_056 ILIFGAQNRFRLNKKKIFKGHMVAGYACQVD---------FSPDMSY-----VISGDGNG
          490       500       510                520            530

             440       450       460        470       480     
pF1KB3 CVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDE-SLLASSDASGMVIVWRREQK
        ....:  ...:   .....:.   . . ..  : : . .   .:.. .:     
NP_056 KLNIWDW-KTTKL-YSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD    
               540        550       560       570             

>>NP_001128304 (OMIM: 608629,608894) jouberin isoform b   (1053 aa)
 initn: 129 init1:  95 opt: 201  Z-score: 192.3  bits: 46.1 E(85289): 0.00057
Smith-Waterman score: 203; 21.5% identity (49.9% similar) in 381 aa overlap (114-469:548-903)

            90       100       110       120       130         140 
pF1KB3 RSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQMNRAVYEDR--PPGSVVPTSA
                                     :. . :: . .. :. .:    .::    .
NP_001 WSKCPRNHYPSTLYVTVRGLKVPDCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPG
       520       530       540       550       560       570       

             150       160       170       180            190      
pF1KB3 AEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRH--RL---ACCSLDGS
        : :. .     :  .       :.:. .. :   :  :  :  :  :.   :: : :: 
NP_001 LEESKEVIKWKRLPGQACRIPNKHLFSLNAGE---RGCFCLDFSHNGRILAAACASRDGY
       580       590       600          610       620       630    

        200       210       220       230       240         250    
pF1KB3 ISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASE--DGRCIRE
         .   .:.    .: : ::   . :..:: ..  ....: :.: ::: .:  .   .: 
NP_001 PIILYEIPSG-RFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRV
          640        650       660       670       680       690   

          260       270       280       290       300              
pF1KB3 IPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGR-------V
       .: :  . .    :.:.  .:.:.:     ... ..    ...  :. :. .       .
NP_001 LPHP--SFVYTAKFHPAVRELVVTGCYDSMIRIWKV----EMREDSAILVRQFDVHKSFI
             700       710       720           730       740       

       310       320       330                340       350        
pF1KB3 LALSFDAPGRLLWAGDDRGSVFSF-----LFDMATG----KLTKAKRLVVHEGSPVTSIS
        .: ::. :. ...::  : .  .     . :.  .     ..:  . .  .: :.. . 
NP_001 NSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKETEFKGIPISYLE
       750       760       770       780       790       800       

      360       370       380       390       400       410        
pF1KB3 ARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSF
        .   .:      :::..  . :   :..: .  :  ..     .  . ..: . :  .:
NP_001 IHPNGKR------LLIHTKDSTL---RIMDLR-ILVARKFVGAANYREKIHSTLTPCGTF
       810             820          830        840       850       

      420       430       440       450       460       470        
pF1KB3 RQGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVI
            . .::::  :. .. : . ..:. .    ..:. :.:..  :...:         
NP_001 -----LFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEP
            860       870       880       890       900       910  

      480                                                          
pF1KB3 VWRREQK                                                     
                                                                   
NP_001 ILLYIYDFHVAQQEAEMFKRYNGTFPLPGIHQSQDALCTCPKLPHQGSFQIDEFVHTESS
            920       930       940       950       960       970  




485 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:23:27 2016 done: Sat Nov  5 05:23:28 2016
 Total Scan time:  9.160 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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