Result of FASTA (ccds) for
pF1KB3050
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3050, 540 aa
1>>>pF1KB3050 540 - 540 aa - 540 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7468+/-0.000757; mu= 17.3075+/- 0.046
mean_var=83.2004+/-16.538, 0's: 0 Z-trim(110.0): 23 B-trim: 43 in 1/49
Lambda= 0.140609
statistics sampled from 11236 (11259) to 11236 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.346), width: 16
Scan time: 2.520
The best scores are: opt bits E(32554)
CCDS46839.1 PARP3 gene_id:10039|Hs108|chr3 ( 540) 3649 749.9 1.7e-216
CCDS43097.1 PARP3 gene_id:10039|Hs108|chr3 ( 533) 3609 741.8 4.7e-214
CCDS41910.1 PARP2 gene_id:10038|Hs108|chr14 ( 583) 934 199.2 1.1e-50
CCDS45077.1 PARP2 gene_id:10038|Hs108|chr14 ( 570) 931 198.5 1.7e-50
CCDS1554.1 PARP1 gene_id:142|Hs108|chr1 (1014) 715 154.9 4.2e-37
>>CCDS46839.1 PARP3 gene_id:10039|Hs108|chr3 (540 aa)
initn: 3649 init1: 3649 opt: 3649 Z-score: 4000.1 bits: 749.9 E(32554): 1.7e-216
Smith-Waterman score: 3649; 100.0% identity (100.0% similar) in 540 aa overlap (1-540:1-540)
10 20 30 40 50 60
pF1KB3 MSLLFLAMAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTAEALKAIPAEKRIIRVDPTCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MSLLFLAMAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTAEALKAIPAEKRIIRVDPTCP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQSKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQSKIN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 HFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 HFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 RTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LAQALQAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LAQALQAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 TLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 YFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 YFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 HTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 HTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL
490 500 510 520 530 540
>>CCDS43097.1 PARP3 gene_id:10039|Hs108|chr3 (533 aa)
initn: 3609 init1: 3609 opt: 3609 Z-score: 3956.4 bits: 741.8 E(32554): 4.7e-214
Smith-Waterman score: 3609; 100.0% identity (100.0% similar) in 533 aa overlap (8-540:1-533)
10 20 30 40 50 60
pF1KB3 MSLLFLAMAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTAEALKAIPAEKRIIRVDPTCP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTAEALKAIPAEKRIIRVDPTCP
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 LSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQSKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQSKIN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 HFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 HFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 RTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 RTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEAL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 EALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 EALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 LAQALQAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 LAQALQAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 TLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 TLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGI
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 YFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 YFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARG
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 HTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 HTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL
480 490 500 510 520 530
>>CCDS41910.1 PARP2 gene_id:10038|Hs108|chr14 (583 aa)
initn: 705 init1: 138 opt: 934 Z-score: 1023.1 bits: 199.2 E(32554): 1.1e-50
Smith-Waterman score: 935; 35.2% identity (64.9% similar) in 542 aa overlap (20-540:54-577)
10 20 30 40
pF1KB3 MSLLFLAMAPKPKPWVQTEGPEKKKGRQAGREED-PFRSTA-----EAL
: . .: : ... : :: : :..
CCDS41 NNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDGMPGRSWASKRVSESV
30 40 50 60 70 80
50 60 70 80 90
pF1KB3 KAIPAEKRIIRVDPTCPLSSNPG-TQVYED----YNCTLNQTNIENNNNKFYIIQLLQD-
::. . . ::: : ... : ..:: . :. :::::.. ::::.:.::::.:
CCDS41 KALLLKGKAP-VDPEC--TAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDD
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB3 SNRFFTCWNRWGRVGEVGQ-SKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGK
..: :. : ::::::..:: : . :. ::. :.::: .:::::: .:..: . :::
CCDS41 AQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGK
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB3 YTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQPCS-LDPATQKLITNIFSKEMFKNTMAL
: ..... ..:. . . ... . ..: : :: .:.:: : . . ... :
CCDS41 YDMLQMDYATNTQD---EEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMME
210 220 230 240 250
220 230 240 250 260 270
pF1KB3 MDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHS
: ..:: :::::. :: :...:. .:. ... : ..: : ..::: :::.::
CCDS41 MKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHG-RALMEACNEFYTRIPHDFGLR
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB3 QPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVPHPLDRDYQLLKCQLQL
:: : . . :. : ..: .:.:::. :.. :. . .. : ::::. :. :.: :.
CCDS41 TPPLIRTQKELSEKIQLLEALGDIEI--AIKLVKTELQSPE---HPLDQHYRNLHCALRP
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB3 LDSGAPEYKVIQTYLEQTGS-NHR--CPTLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHG
:: . :.:::. ::..: . .: :: ...:...::.. :. : :: :::::
CCDS41 LDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFRED--LHNRMLLWHG
380 390 400 410 420
400 410 420 430 440
pF1KB3 TNMAVVAAILTSGLRIMPH----SGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFL
. :. ..::. :::: : .: :::::::. .::::.: .. . ...: ..:
CCDS41 SRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASR--LKNTGLLLL
430 440 450 460 470 480
450 460 470 480 490 500
pF1KB3 GEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVPQGQPVP
.:::::. ... ::. .. : :. .: . :.. . :.:. : . .. .
CCDS41 SEVALGQCNELLEANPKAEGLLQGKHST--KGLGKMAPSSAHFVTLNGSTVPLGPASDTG
490 500 510 520 530 540
510 520 530 540
pF1KB3 CPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL
. .. :.. .::..:. .: :.::::.:..
CCDS41 ILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW
550 560 570 580
>>CCDS45077.1 PARP2 gene_id:10038|Hs108|chr14 (570 aa)
initn: 705 init1: 138 opt: 931 Z-score: 1020.0 bits: 198.5 E(32554): 1.7e-50
Smith-Waterman score: 931; 35.4% identity (65.4% similar) in 537 aa overlap (22-540:46-564)
10 20 30 40
pF1KB3 MSLLFLAMAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTA---EALKAIPA
:.:: :: . . :. :..::.
CCDS45 ALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTEDKQDESVKALLL
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB3 EKRIIRVDPTCPLSSNPG-TQVYED----YNCTLNQTNIENNNNKFYIIQLLQD-SNRFF
. . ::: : ... : ..:: . :. :::::.. ::::.:.::::.: ..: :
CCDS45 KGKAP-VDPEC--TAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNF
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB3 TCWNRWGRVGEVGQ-SKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIE
. : ::::::..:: : . :. ::. :.::: .:::::: .:..: . :::: ...
CCDS45 SVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQ
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB3 VQAEDEAQEAVVKVDRGPVRTVTKRVQPCS-LDPATQKLITNIFSKEMFKNTMALMDLDV
.. ..:. . . ... . ..: : :: .:.:: : . . ... : : ..
CCDS45 MDYATNTQD---EEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNT
200 210 220 230 240
230 240 250 260 270 280
pF1KB3 KKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPI
:: :::::. :: :...:. .:. ... . :..: : ..::: :::.:: :: :
CCDS45 KKAPLGKLTVAQIKAGYQSLKKIEDCIRAG-QHGRALMEACNEFYTRIPHDFGLRTPPLI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB3 NSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGA
. . :. : ..: .:.:::.: .. :. . .. : ::::. :. :.: :. :: .
CCDS45 RTQKELSEKIQLLEALGDIEIA--IKLVKTELQSPE---HPLDQHYRNLHCALRPLDHES
310 320 330 340 350 360
350 360 370 380 390
pF1KB3 PEYKVIQTYLEQTGS-NHR--CPTLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAV
:.:::. ::..: . .: :: ...:...::.. :. : :: :::::. :.
CCDS45 YEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFRE--DLHNRMLLWHGSRMSN
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 VAAILTSGLRIMPH----SGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVAL
..::. :::: : .: :::::::. .::::.: .. . ...: ..:.::::
CCDS45 WVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRL--KNTGLLLLSEVAL
430 440 450 460 470
460 470 480 490 500 510
pF1KB3 GREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFS
:. ... ::. .. : : ..: . :.. . :.:. : . .. . . .
CCDS45 GQCNELLEANPKAEGLLQGKHS--TKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPD
480 490 500 510 520 530
520 530 540
pF1KB3 SSTFSQSEYLIYQESQCRLRYLLEVHL
. :.. .::..:. .: :.::::.:..
CCDS45 GYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW
540 550 560 570
>>CCDS1554.1 PARP1 gene_id:142|Hs108|chr1 (1014 aa)
initn: 609 init1: 159 opt: 715 Z-score: 779.6 bits: 154.9 E(32554): 4.2e-37
Smith-Waterman score: 867; 33.8% identity (64.6% similar) in 565 aa overlap (4-540:472-1007)
10 20
pF1KB3 MSLLFLA--MAP-----KPKPWVQTEGPEKKKG
:::: ..: : .: :.. .:. :.:
CCDS15 KMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEP-VEVVAPRGKSG
450 460 470 480 490 500
30 40 50 60 70
pF1KB3 -----RQAGR-EEDPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYED----YNCT
.. :. .:. . .. . .: . : ::: : . ..: : .. :
CCDS15 AALSKKSKGQVKEEGINKSEKRMKL--TLKGGAAVDPDSGLEHS--AHVLEKGGKVFSAT
510 520 530 540 550
80 90 100 110 120 130
pF1KB3 LNQTNIENNNNKFYIIQLLQDS--NRFFTCWNRWGRVGEV-GQSKINHFTRLEDAKKDFE
:. ..: ...:..: .:::.:. ::.. . ::::: : :..:.... ::: . :
CCDS15 LGLVDIVKGTNSYYKLQLLEDDKENRYWI-FRSWGRVGTVIGSNKLEQMPSKEDAIEHFM
560 570 580 590 600 610
140 150 160 170 180 190
pF1KB3 KKFREKTKNNWAERDHFVSHPGKYTLIEVQ-AEDEAQEAVVKVDRGPVRTVTKRVQPCSL
: ..::: : : .. :...: :. .:.. ..:: ::: :. .: : .: .:
CCDS15 KLYEEKTGNAWHSKN-FTKYPKKFYPLEIDYGQDE--EAVKKLTVNP-GTKSKLPKP---
620 630 640 650 660
200 210 220 230 240 250
pF1KB3 DPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTD
.: :: ::. : .:..:. ...:..:::::::::.:: .. : ...:.. ..
CCDS15 ---VQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSS
670 680 690 700 710 720
260 270 280 290 300 310
pF1KB3 GGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQE
.: :. ::..:::.:::.:: ..:: .:. . .::: .:: : :::.: .: . ..
CCDS15 DSQILD-LSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDD
730 740 750 760 770 780
320 330 340 350 360
pF1KB3 KTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQT-GSNHRCPTLQ--HIWKVN
.. . :.: .:. :: .....: . : ..:. :...: ...: :. :.:..
CCDS15 SSKD----PIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIE
790 800 810 820 830 840
370 380 390 400 410 420
pF1KB3 QEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYFASE
.::: .:.. ..: ::.:::::. . :.::..:::: : .: :::::::.
CCDS15 REGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADM
850 860 870 880 890 900
430 440 450 460 470 480
pF1KB3 NSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPD
::::.: . .: ..::::::: .... . ... : : :: . :.: ::
CCDS15 VSKSANYC--HTSQGDPIGLILLGEVALGNMYELKHAS-HISKLPKGKHSVKGLGKTTPD
910 920 930 940 950
490 500 510 520 530 540
pF1KB3 PTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL
:. . . ::: : :: : . ..... .::..:. .: :.:::....
CCDS15 PSAN--ISLDG--VDVPLGTGISSG-VNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTS
960 970 980 990 1000 1010
CCDS15 LW
540 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:48:55 2016 done: Sat Nov 5 04:48:55 2016
Total Scan time: 2.520 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]