Result of FASTA (omim) for pF1KE0924
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0924, 343 aa
  1>>>pF1KE0924 343 - 343 aa - 343 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6423+/-0.00033; mu= 12.9064+/- 0.021
 mean_var=181.4565+/-37.283, 0's: 0 Z-trim(121.6): 288  B-trim: 136 in 2/52
 Lambda= 0.095211
 statistics sampled from 38087 (38479) to 38087 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.451), width:  16
 Scan time:  9.630

The best scores are:                                      opt bits E(85289)
NP_006184 (OMIM: 125853,167413,612225,612227) pair ( 343) 2389 339.9 4.9e-93
XP_011514578 (OMIM: 125853,167413,612225,612227) P ( 351) 2389 339.9 4.9e-93
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401)  630 98.3 2.9e-20
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422)  630 98.4   3e-20
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422)  630 98.4   3e-20
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422)  630 98.4   3e-20
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422)  630 98.4   3e-20
NP_001267483 (OMIM: 167414,615545) paired box prot ( 348)  586 92.2 1.8e-18
NP_039246 (OMIM: 167415,218700) paired box protein ( 398)  586 92.3 1.9e-18
XP_016860368 (OMIM: 167415,218700) PREDICTED: pair ( 402)  586 92.3 1.9e-18
NP_001267482 (OMIM: 167414,615545) paired box prot ( 319)  582 91.6 2.4e-18
XP_011510094 (OMIM: 167415,218700) PREDICTED: pair ( 455)  574 90.7 6.5e-18
XP_016860367 (OMIM: 167415,218700) PREDICTED: pair ( 459)  574 90.7 6.6e-18
NP_054698 (OMIM: 167415,218700) paired box protein ( 287)  566 89.4   1e-17
NP_000269 (OMIM: 120330,167409,191830,616002) pair ( 394)  565 89.4 1.4e-17
NP_003979 (OMIM: 120330,167409,191830,616002) pair ( 396)  565 89.4 1.4e-17
NP_003980 (OMIM: 120330,167409,191830,616002) pair ( 409)  565 89.4 1.4e-17
XP_016871777 (OMIM: 120330,167409,191830,616002) P ( 424)  565 89.4 1.5e-17
NP_001291498 (OMIM: 120330,167409,191830,616002) p ( 425)  565 89.4 1.5e-17
XP_016871776 (OMIM: 120330,167409,191830,616002) P ( 427)  565 89.5 1.5e-17
XP_016871775 (OMIM: 120330,167409,191830,616002) P ( 440)  565 89.5 1.5e-17
NP_003978 (OMIM: 120330,167409,191830,616002) pair ( 417)  560 88.8 2.3e-17
NP_003981 (OMIM: 120330,167409,191830,616002) pair ( 432)  560 88.8 2.4e-17
NP_039247 (OMIM: 167415,218700) paired box protein ( 321)  558 88.3 2.4e-17
XP_016871774 (OMIM: 120330,167409,191830,616002) P ( 448)  560 88.8 2.4e-17
XP_016871773 (OMIM: 120330,167409,191830,616002) P ( 463)  560 88.8 2.5e-17
XP_011510096 (OMIM: 167415,218700) PREDICTED: pair ( 387)  558 88.4 2.7e-17
NP_003457 (OMIM: 167415,218700) paired box protein ( 450)  558 88.5   3e-17
NP_001267479 (OMIM: 167414,615545) paired box prot ( 295)  552 87.5   4e-17
NP_001267478 (OMIM: 167414,615545) paired box prot ( 324)  551 87.4 4.7e-17
XP_011510095 (OMIM: 167415,218700) PREDICTED: pair ( 444)  546 86.9 9.2e-17
XP_011510093 (OMIM: 167415,218700) PREDICTED: pair ( 500)  546 86.9   1e-16
XP_011510092 (OMIM: 167415,218700) PREDICTED: pair ( 507)  546 86.9   1e-16
NP_001267481 (OMIM: 167414,615545) paired box prot ( 328)  542 86.2 1.1e-16
NP_001267476 (OMIM: 167414,615545) paired box prot ( 357)  542 86.2 1.2e-16
NP_001267477 (OMIM: 167414,615545) paired box prot ( 362)  542 86.2 1.2e-16
XP_005251538 (OMIM: 167414,615545) PREDICTED: pair ( 390)  542 86.2 1.2e-16
NP_057953 (OMIM: 167414,615545) paired box protein ( 391)  542 86.2 1.2e-16
XP_011516199 (OMIM: 167414,615545) PREDICTED: pair ( 409)  542 86.3 1.3e-16
XP_011516198 (OMIM: 167414,615545) PREDICTED: pair ( 410)  542 86.3 1.3e-16
XP_016871778 (OMIM: 120330,167409,191830,616002) P ( 374)  538 85.7 1.8e-16
XP_016871772 (OMIM: 120330,167409,191830,616002) P ( 483)  538 85.8 2.1e-16
XP_016871771 (OMIM: 120330,167409,191830,616002) P ( 483)  538 85.8 2.1e-16
XP_016871770 (OMIM: 120330,167409,191830,616002) P ( 496)  538 85.8 2.1e-16
NP_006185 (OMIM: 167416,604625) paired box protein ( 341)  483 78.1 3.1e-14
NP_001244025 (OMIM: 167411,615560) paired box prot ( 457)  480 77.8   5e-14
NP_006183 (OMIM: 167411,615560) paired box protein ( 534)  480 77.9 5.6e-14
NP_039236 (OMIM: 167410,268220) paired box protein ( 518)  470 76.5 1.4e-13
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483)  468 76.2 1.6e-13
NP_039230 (OMIM: 122880,148820,193500,268220,60659 ( 206)  453 73.7   4e-13


>>NP_006184 (OMIM: 125853,167413,612225,612227) paired b  (343 aa)
 initn: 2389 init1: 2389 opt: 2389  Z-score: 1791.3  bits: 339.9 E(85289): 4.9e-93
Smith-Waterman score: 2389; 99.7% identity (99.7% similar) in 343 aa overlap (1-343:1-343)

               10        20        30        40        50        60
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 VAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLP
              250       260       270       280       290       300

              310       320       330       340   
pF1KE0 PQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
       :::::::::::::::::::: ::::::::::::::::::::::
NP_006 PQPNSLDSGLLCLPCPSSHCHLASLSGSQALLWPGCPLLYGLE
              310       320       330       340   

>>XP_011514578 (OMIM: 125853,167413,612225,612227) PREDI  (351 aa)
 initn: 2389 init1: 2389 opt: 2389  Z-score: 1791.2  bits: 339.9 E(85289): 4.9e-93
Smith-Waterman score: 2389; 99.7% identity (99.7% similar) in 343 aa overlap (1-343:9-351)

                       10        20        30        40        50  
pF1KE0         MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGR
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHQDGISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGR
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KE0 YYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPS
               70        80        90       100       110       120

            120       130       140       150       160       170  
pF1KE0 VSSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPS
              130       140       150       160       170       180

            180       190       200       210       220       230  
pF1KE0 QAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGA
              190       200       210       220       230       240

            240       250       260       270       280       290  
pF1KE0 SQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACL
              250       260       270       280       290       300

            300       310       320       330       340   
pF1KE0 KPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
       :::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 KPCWGHLPPQPNSLDSGLLCLPCPSSHCHLASLSGSQALLWPGCPLLYGLE
              310       320       330       340       350 

>>NP_001297088 (OMIM: 106210,120430,136520,148190,165550  (401 aa)
 initn: 873 init1: 618 opt: 630  Z-score: 484.8  bits: 98.3 E(85289): 2.9e-20
Smith-Waterman score: 812; 42.5% identity (60.6% similar) in 381 aa overlap (1-336:8-372)

                      10        20        30        40        50   
pF1KE0        MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
              .:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_001 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
       :.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_001 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
               70        80        90       100       110       120

           120        130       140       150        160           
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
       :::::::: : .: : .    . .   .    :. ..::   : : .:::.         
NP_001 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
              130       140           150       160       170      

                                              170       180        
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
                                         .:::: :.  : :::::::.: .:::
NP_001 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
        180       190       200       210       220       230      

      190       200       210       220       230       240        
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
         :: .::.  .:::  ..::::::::::::.:::. . .  . . .  .: .. .. ..
NP_001 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPS-HIP-ISSSFSTS
        240       250       260       270       280         290    

      250       260       270       280       290       300        
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPNSLDS
         .:   ::. . ..   :    .    ::     :  ::   .    ..:: : ..  .
NP_001 VYQPIPQPTTPVSSFTS-GSMLGRT--DTALTNTYSALPPMPSFTMA-NNLPMQVSAAGG
          300       310          320       330        340       350

      310       320       330       340                         
pF1KE0 GLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE                      
       ::   : :     . : ::   :.  ::                             
NP_001 GLHN-PGPR---EVRSGSGPADLI--GCVCTLESFSHYSDWLDQSSRRQSIPSLLSD
                  360       370         380       390       400 

>>NP_001245394 (OMIM: 106210,120430,136520,148190,165550  (422 aa)
 initn: 935 init1: 618 opt: 630  Z-score: 484.5  bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)

                      10        20        30        40        50   
pF1KE0        MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
              .:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_001 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
       :.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_001 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
               70        80        90       100       110       120

           120        130       140       150        160           
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
       :::::::: : .: : .    . .   .    :. ..::   : : .:::.         
NP_001 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
              130       140           150       160       170      

                                              170       180        
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
                                         .:::: :.  : :::::::.: .:::
NP_001 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
        180       190       200       210       220       230      

      190       200       210       220       230       240        
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
         :: .::.  .:::  ..::::::::::::.:::. . .     :. ..:   :  ::.
NP_001 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
        240       250       260       270            280           

      250       260       270       280       290       300        
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
       . :     ..  :  .:  :      ....     .::     :   .. :::.:. .. 
NP_001 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
     290           300          310       320           330        

       310       320       330       340                           
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE                        
       ..:   :      :. : ..: . . :  : . :                          
NP_001 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
      340             350       360       370       380       390  

NP_001 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
            400       410       420  

>>NP_001245393 (OMIM: 106210,120430,136520,148190,165550  (422 aa)
 initn: 935 init1: 618 opt: 630  Z-score: 484.5  bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)

                      10        20        30        40        50   
pF1KE0        MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
              .:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_001 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
       :.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_001 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
               70        80        90       100       110       120

           120        130       140       150        160           
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
       :::::::: : .: : .    . .   .    :. ..::   : : .:::.         
NP_001 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
              130       140           150       160       170      

                                              170       180        
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
                                         .:::: :.  : :::::::.: .:::
NP_001 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
        180       190       200       210       220       230      

      190       200       210       220       230       240        
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
         :: .::.  .:::  ..::::::::::::.:::. . .     :. ..:   :  ::.
NP_001 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
        240       250       260       270            280           

      250       260       270       280       290       300        
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
       . :     ..  :  .:  :      ....     .::     :   .. :::.:. .. 
NP_001 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
     290           300          310       320           330        

       310       320       330       340                           
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE                        
       ..:   :      :. : ..: . . :  : . :                          
NP_001 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
      340             350       360       370       380       390  

NP_001 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
            400       410       420  

>>NP_001121084 (OMIM: 106210,120430,136520,148190,165550  (422 aa)
 initn: 935 init1: 618 opt: 630  Z-score: 484.5  bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)

                      10        20        30        40        50   
pF1KE0        MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
              .:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_001 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
       :.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_001 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
               70        80        90       100       110       120

           120        130       140       150        160           
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
       :::::::: : .: : .    . .   .    :. ..::   : : .:::.         
NP_001 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
              130       140           150       160       170      

                                              170       180        
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
                                         .:::: :.  : :::::::.: .:::
NP_001 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
        180       190       200       210       220       230      

      190       200       210       220       230       240        
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
         :: .::.  .:::  ..::::::::::::.:::. . .     :. ..:   :  ::.
NP_001 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
        240       250       260       270            280           

      250       260       270       280       290       300        
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
       . :     ..  :  .:  :      ....     .::     :   .. :::.:. .. 
NP_001 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
     290           300          310       320           330        

       310       320       330       340                           
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE                        
       ..:   :      :. : ..: . . :  : . :                          
NP_001 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
      340             350       360       370       380       390  

NP_001 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
            400       410       420  

>>NP_000271 (OMIM: 106210,120430,136520,148190,165550,19  (422 aa)
 initn: 935 init1: 618 opt: 630  Z-score: 484.5  bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)

                      10        20        30        40        50   
pF1KE0        MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
              .:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
NP_000 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
       :.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
NP_000 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
               70        80        90       100       110       120

           120        130       140       150        160           
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
       :::::::: : .: : .    . .   .    :. ..::   : : .:::.         
NP_000 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
              130       140           150       160       170      

                                              170       180        
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
                                         .:::: :.  : :::::::.: .:::
NP_000 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
        180       190       200       210       220       230      

      190       200       210       220       230       240        
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
         :: .::.  .:::  ..::::::::::::.:::. . .     :. ..:   :  ::.
NP_000 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
        240       250       260       270            280           

      250       260       270       280       290       300        
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
       . :     ..  :  .:  :      ....     .::     :   .. :::.:. .. 
NP_000 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
     290           300          310       320           330        

       310       320       330       340                           
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE                        
       ..:   :      :. : ..: . . :  : . :                          
NP_000 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
      340             350       360       370       380       390  

NP_000 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
            400       410       420  

>>NP_001267483 (OMIM: 167414,615545) paired box protein   (348 aa)
 initn: 578 init1: 531 opt: 586  Z-score: 452.8  bits: 92.2 E(85289): 1.8e-18
Smith-Waterman score: 586; 38.2% identity (61.8% similar) in 322 aa overlap (1-308:20-325)

                                  10        20        30        40 
pF1KE0                    MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV
                          .:::::.::::::::  .::.::.:: .:.::::::: :.:
NP_001 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
               10        20        30        40        50        60

              50        60        70        80        90       100 
pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA
       :.:::::::::::.:: ..:  ::::::..::: :: .::. : . :..:::::. .: :
NP_001 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA
               70        80        90       100       110       120

             110       120          130       140         150      
pF1KE0 EGLCTQDKTPSVSSINRVLRA-LQE--DQGLPCTRLRSPAVLAPAVLTPHS--GSETPRG
       : .: .: .::::::::..:. .:.  .: .: .  .: ..    : . ::  : .  : 
NP_001 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASS-HSIGIQESPVPNGHSLPGRDFLRK
              130       140       150        160       170         

        160       170       180       190       200       210      
pF1KE0 THPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAK
          :       .:. .: :.:.. :.: .: :  .    .:    ::.:..  .:   . 
NP_001 QMRGD------LFTQQQLEVLDRVFERQHYSDIFT----TTEPIKPEQTTE--YSAMASL
     180             190       200           210       220         

        220       230          240       250       260       270   
pF1KE0 WRRQEKLKWEMQLPG-ASQGLTVP--RVAPGIISAQQSPGSVPTAALPALEPLGPSCYQL
           . .: ..  :  :. : .::  .  : . . . .  ..:    : . : : . :. 
NP_001 AGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYP-PHVPPAGQGSYSA
       230       240       250       260       270        280      

             280           290       300       310       320       
pF1KE0 CWATA--PERCLSDTP---PK-ACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSG
          :.  :   .: .:   :. .  .  :    :.:. : :                   
NP_001 PTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF--PNPGLLGSPYYYSAAARGAAPPAAATA
        290       300       310         320       330       340    

       330       340   
pF1KE0 SQALLWPGCPLLYGLE
                       
NP_001 YDRH            
                       

>>NP_039246 (OMIM: 167415,218700) paired box protein Pax  (398 aa)
 initn: 619 init1: 533 opt: 586  Z-score: 452.1  bits: 92.3 E(85289): 1.9e-18
Smith-Waterman score: 587; 36.8% identity (55.6% similar) in 383 aa overlap (1-321:13-385)

                           10        20        30        40        
pF1KE0             MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK
                   .::::: ::::::::  .::.:: :: .:.::::::: :.::.:::::
NP_039 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD
       ::::::.:: ..:  ::::::..::: :: .:.. : . :..:::::. .: :::.: .:
NP_039 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

      110       120        130             140         150         
pF1KE0 KTPSVSSINRVLRA-LQEDQGLP---C--TRLRSPA-VLAP--AVLTPHSGSETPRGT--
        .::::::::..:. .:.  .::   :  :.  ::. .: :  ::  :.: .    :.  
NP_039 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

                160                                  170       180 
pF1KE0 ---------HPGTGHRN--------------------------RT-IFSPSQAEALEKEF
                .::. .:.                          ::  ::  . : ::  :
NP_039 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240

             190       200         210        220       230        
pF1KE0 QRGQYPDSVARGKLATATS--LPEDTVRVWFSNRRAKWR-RQEKLKWEMQLPGASQGLTV
       .: .::.. :  . . . .   :   .   ... .:     .  :  ..     :   : 
NP_039 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNL-----STHQTY
              250       260       270       280            290     

      240         250       260             270       280       290
pF1KE0 PRVA--PGIISAQQSPGSVPTAALPALEP-LG-----PSCYQLCWATAPERCLSDTPPKA
       : ::  :  : ....::: :.  .: : :  :     ::     :  .: ::  :: : .
NP_039 PVVAAPPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQGERWW-GP-RC-PDTHPTS
         300       310       320       330       340          350  

               300          310       320       330       340   
pF1KE0 CLKPC-WGHLPPQPNSL---DSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
          :   . .:: :..    . . : .:  .   :                      
NP_039 --PPADRAAMPPLPSQAWWQEVNTLAMPMATPPTPPTARPGASPTPAC         
              360       370       380       390                 

>>XP_016860368 (OMIM: 167415,218700) PREDICTED: paired b  (402 aa)
 initn: 619 init1: 533 opt: 586  Z-score: 452.1  bits: 92.3 E(85289): 1.9e-18
Smith-Waterman score: 586; 36.6% identity (60.0% similar) in 350 aa overlap (1-337:13-346)

                           10        20        30        40        
pF1KE0             MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK
                   .::::: ::::::::  .::.:: :: .:.::::::: :.::.:::::
XP_016 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD
       ::::::.:: ..:  ::::::..::: :: .:.. : . :..:::::. .: :::.: .:
XP_016 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

      110       120        130       140        150          160   
pF1KE0 KTPSVSSINRVLRA-LQEDQGLPCTRLRSPAVLAPA-VLTPHSG---SETPRGTHPGTGH
        .::::::::..:. .:.  .::     .   :.:. .: : :.    :.:..   :. .
XP_016 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

           170       180       190       200        210       220  
pF1KE0 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRV-WFSNRRAKWRRQEK
           ... .:  . ..... ..  .        ...: :.  .:.  ::        :..
XP_016 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFS--------QHH
              190       200       210       220               230  

            230       240       250       260        270       280 
pF1KE0 LKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEP-LGPSCYQLCWATAPE-
       :.  .. :   :      ..:.  ...:  :  :   :: :.  :  .   :  ...:  
XP_016 LE-PLECPFERQHYPEAYASPSHTKGEQ--GLYP---LPLLNSTLDDGKATLTPSNTPLG
             240       250         260          270       280      

                290       300       310         320       330      
pF1KE0 RCLS--DTPPKACLKPCWGHLPPQPNSLDSGLLCL--PCPSSHCPLASLSGSQALLW-PG
       : ::  .: : .   : :      :.:  :  . .  :: .:     : .: .   : : 
XP_016 RNLSTHQTYPVVAAPPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQGER--WWGPR
        290       300       310       320       330         340    

         340                                                     
pF1KE0 CPLLYGLE                                                  
       ::                                                        
XP_016 CPDTHPTSPPADRAAMPPLPSQAWWQVRRGPAGRGALQRGSIGARWDTRSKRHTVPYS
          350       360       370       380       390       400  




343 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:31:21 2016 done: Sat Nov  5 04:31:23 2016
 Total Scan time:  9.630 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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