Result of FASTA (ccds) for pF1KE0924
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0924, 343 aa
  1>>>pF1KE0924 343 - 343 aa - 343 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4162+/-0.000781; mu= 14.1448+/- 0.047
 mean_var=174.1678+/-35.847, 0's: 0 Z-trim(114.4): 181  B-trim: 0 in 0/53
 Lambda= 0.097183
 statistics sampled from 14723 (14940) to 14723 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.459), width:  16
 Scan time:  3.010

The best scores are:                                      opt bits E(32554)
CCDS5797.1 PAX4 gene_id:5078|Hs108|chr7            ( 343) 2389 346.5 1.9e-95
CCDS31451.1 PAX6 gene_id:5080|Hs108|chr11          ( 422)  630 100.0 3.7e-21
CCDS65043.1 PAX5 gene_id:5079|Hs108|chr9           ( 348)  586 93.7 2.4e-19
CCDS46399.1 PAX8 gene_id:7849|Hs108|chr2           ( 398)  586 93.8 2.6e-19
CCDS65042.1 PAX5 gene_id:5079|Hs108|chr9           ( 319)  582 93.1 3.3e-19
CCDS42735.1 PAX8 gene_id:7849|Hs108|chr2           ( 287)  566 90.8 1.5e-18
CCDS41561.1 PAX2 gene_id:5076|Hs108|chr10          ( 394)  565 90.9   2e-18
CCDS7499.1 PAX2 gene_id:5076|Hs108|chr10           ( 396)  565 90.9   2e-18
CCDS42736.1 PAX8 gene_id:7849|Hs108|chr2           ( 321)  558 89.8 3.4e-18
CCDS46398.1 PAX8 gene_id:7849|Hs108|chr2           ( 450)  558 89.9 4.2e-18
CCDS65044.1 PAX5 gene_id:5079|Hs108|chr9           ( 295)  552 88.9 5.8e-18
CCDS65045.1 PAX5 gene_id:5079|Hs108|chr9           ( 324)  551 88.8 6.8e-18
CCDS65046.1 PAX5 gene_id:5079|Hs108|chr9           ( 328)  542 87.5 1.6e-17
CCDS65047.1 PAX5 gene_id:5079|Hs108|chr9           ( 357)  542 87.6 1.7e-17
CCDS65048.1 PAX5 gene_id:5079|Hs108|chr9           ( 362)  542 87.6 1.7e-17
CCDS6607.1 PAX5 gene_id:5079|Hs108|chr9            ( 391)  542 87.6 1.8e-17
CCDS9662.1 PAX9 gene_id:5083|Hs108|chr14           ( 341)  483 79.3 5.2e-15
CCDS74709.1 PAX1 gene_id:5075|Hs108|chr20          ( 457)  480 79.0 8.3e-15
CCDS13146.2 PAX1 gene_id:5075|Hs108|chr20          ( 534)  480 79.1 9.2e-15
CCDS44075.1 PAX7 gene_id:5081|Hs108|chr1           ( 518)  470 77.7 2.4e-14
CCDS46522.1 PAX3 gene_id:5077|Hs108|chr2           ( 483)  468 77.4 2.8e-14
CCDS2451.1 PAX3 gene_id:5077|Hs108|chr2            ( 206)  453 74.8   7e-14
CCDS46523.1 PAX3 gene_id:5077|Hs108|chr2           ( 215)  453 74.8 7.2e-14
CCDS2450.1 PAX3 gene_id:5077|Hs108|chr2            ( 403)  456 75.6 7.9e-14
CCDS2449.1 PAX3 gene_id:5077|Hs108|chr2            ( 407)  456 75.6   8e-14
CCDS42826.1 PAX3 gene_id:5077|Hs108|chr2           ( 479)  456 75.7 8.8e-14
CCDS42825.1 PAX3 gene_id:5077|Hs108|chr2           ( 484)  456 75.7 8.9e-14
CCDS2448.1 PAX3 gene_id:5077|Hs108|chr2            ( 505)  456 75.7 9.1e-14
CCDS44074.1 PAX7 gene_id:5081|Hs108|chr1           ( 505)  449 74.7 1.8e-13
CCDS186.1 PAX7 gene_id:5081|Hs108|chr1             ( 520)  449 74.7 1.8e-13
CCDS31452.1 PAX6 gene_id:5080|Hs108|chr11          ( 436)  421 70.7 2.5e-12


>>CCDS5797.1 PAX4 gene_id:5078|Hs108|chr7                 (343 aa)
 initn: 2389 init1: 2389 opt: 2389  Z-score: 1827.2  bits: 346.5 E(32554): 1.9e-95
Smith-Waterman score: 2389; 99.7% identity (99.7% similar) in 343 aa overlap (1-343:1-343)

               10        20        30        40        50        60
pF1KE0 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 PKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 RALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 FQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 VAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS57 VAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLP
              250       260       270       280       290       300

              310       320       330       340   
pF1KE0 PQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
       :::::::::::::::::::: ::::::::::::::::::::::
CCDS57 PQPNSLDSGLLCLPCPSSHCHLASLSGSQALLWPGCPLLYGLE
              310       320       330       340   

>>CCDS31451.1 PAX6 gene_id:5080|Hs108|chr11               (422 aa)
 initn: 935 init1: 618 opt: 630  Z-score: 493.3  bits: 100.0 E(32554): 3.7e-21
Smith-Waterman score: 821; 42.1% identity (60.7% similar) in 387 aa overlap (1-341:8-366)

                      10        20        30        40        50   
pF1KE0        MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRY
              .:::::.:::::::: .:::.::.:: :: :::::::::.:::::::::::::
CCDS31 MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRY
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE0 YRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSV
       :.:: ..:..:::::::.::: ::..::: : :::..:::::. .: .::.::.:. :::
CCDS31 YETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSV
               70        80        90       100       110       120

           120        130       140       150        160           
pF1KE0 SSINRVLRAL-QEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTG---------
       :::::::: : .: : .    . .   .    :. ..::   : : .:::.         
CCDS31 SSINRVLRNLASEKQQMGADGMYDKLRM----LNGQTGSWGTRPGWYPGTSVPGQPTQDG
              130       140           150       160       170      

                                              170       180        
pF1KE0 ----------------------------------HRNRTIFSPSQAEALEKEFQRGQYPD
                                         .:::: :.  : :::::::.: .:::
CCDS31 CQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPD
        180       190       200       210       220       230      

      190       200       210       220       230       240        
pF1KE0 SVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISA
         :: .::.  .:::  ..::::::::::::.:::. . .     :. ..:   :  ::.
CCDS31 VFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRR-----QASNTPSHIP--ISS
        240       250       260       270            280           

      250       260       270       280       290       300        
pF1KE0 QQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGHLPPQPN-SLD
       . :     ..  :  .:  :      ....     .::     :   .. :::.:. .. 
CCDS31 SFS----TSVYQPIPQPTTPVS---SFTSGSMLGRTDTA----LTNTYSALPPMPSFTMA
     290           300          310       320           330        

       310       320       330       340                           
pF1KE0 SGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE                        
       ..:   :      :. : ..: . . :  : . :                          
CCDS31 NNLPMQP------PVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTT
      340             350       360       370       380       390  

CCDS31 STGLISPGVSVPVQVPGSEPDMSQYWPRLQ
            400       410       420  

>>CCDS65043.1 PAX5 gene_id:5079|Hs108|chr9                (348 aa)
 initn: 578 init1: 531 opt: 586  Z-score: 460.9  bits: 93.7 E(32554): 2.4e-19
Smith-Waterman score: 586; 38.2% identity (61.8% similar) in 322 aa overlap (1-308:20-325)

                                  10        20        30        40 
pF1KE0                    MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV
                          .:::::.::::::::  .::.::.:: .:.::::::: :.:
CCDS65 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
               10        20        30        40        50        60

              50        60        70        80        90       100 
pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA
       :.:::::::::::.:: ..:  ::::::..::: :: .::. : . :..:::::. .: :
CCDS65 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA
               70        80        90       100       110       120

             110       120          130       140         150      
pF1KE0 EGLCTQDKTPSVSSINRVLRA-LQE--DQGLPCTRLRSPAVLAPAVLTPHS--GSETPRG
       : .: .: .::::::::..:. .:.  .: .: .  .: ..    : . ::  : .  : 
CCDS65 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASS-HSIGIQESPVPNGHSLPGRDFLRK
              130       140       150        160       170         

        160       170       180       190       200       210      
pF1KE0 THPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAK
          :       .:. .: :.:.. :.: .: :  .    .:    ::.:..  .:   . 
CCDS65 QMRGD------LFTQQQLEVLDRVFERQHYSDIFT----TTEPIKPEQTTE--YSAMASL
     180             190       200           210       220         

        220       230          240       250       260       270   
pF1KE0 WRRQEKLKWEMQLPG-ASQGLTVP--RVAPGIISAQQSPGSVPTAALPALEPLGPSCYQL
           . .: ..  :  :. : .::  .  : . . . .  ..:    : . : : . :. 
CCDS65 AGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYP-PHVPPAGQGSYSA
       230       240       250       260       270        280      

             280           290       300       310       320       
pF1KE0 CWATA--PERCLSDTP---PK-ACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSG
          :.  :   .: .:   :. .  .  :    :.:. : :                   
CCDS65 PTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF--PNPGLLGSPYYYSAAARGAAPPAAATA
        290       300       310         320       330       340    

       330       340   
pF1KE0 SQALLWPGCPLLYGLE
                       
CCDS65 YDRH            
                       

>>CCDS46399.1 PAX8 gene_id:7849|Hs108|chr2                (398 aa)
 initn: 619 init1: 533 opt: 586  Z-score: 460.3  bits: 93.8 E(32554): 2.6e-19
Smith-Waterman score: 587; 36.8% identity (55.6% similar) in 383 aa overlap (1-321:13-385)

                           10        20        30        40        
pF1KE0             MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK
                   .::::: ::::::::  .::.:: :: .:.::::::: :.::.:::::
CCDS46 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD
       ::::::.:: ..:  ::::::..::: :: .:.. : . :..:::::. .: :::.: .:
CCDS46 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

      110       120        130             140         150         
pF1KE0 KTPSVSSINRVLRA-LQEDQGLP---C--TRLRSPA-VLAP--AVLTPHSGSETPRGT--
        .::::::::..:. .:.  .::   :  :.  ::. .: :  ::  :.: .    :.  
CCDS46 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

                160                                  170       180 
pF1KE0 ---------HPGTGHRN--------------------------RT-IFSPSQAEALEKEF
                .::. .:.                          ::  ::  . : ::  :
CCDS46 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240

             190       200         210        220       230        
pF1KE0 QRGQYPDSVARGKLATATS--LPEDTVRVWFSNRRAKWR-RQEKLKWEMQLPGASQGLTV
       .: .::.. :  . . . .   :   .   ... .:     .  :  ..     :   : 
CCDS46 ERQHYPEAYASPSHTKGEQGLYPLPLLNSTLDDGKATLTPSNTPLGRNL-----STHQTY
              250       260       270       280            290     

      240         250       260             270       280       290
pF1KE0 PRVA--PGIISAQQSPGSVPTAALPALEP-LG-----PSCYQLCWATAPERCLSDTPPKA
       : ::  :  : ....::: :.  .: : :  :     ::     :  .: ::  :: : .
CCDS46 PVVAAPPFWICSKSAPGSRPSMPFPMLPPCTGSSRARPSSQGERWW-GP-RC-PDTHPTS
         300       310       320       330       340          350  

               300          310       320       330       340   
pF1KE0 CLKPC-WGHLPPQPNSL---DSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGLE
          :   . .:: :..    . . : .:  .   :                      
CCDS46 --PPADRAAMPPLPSQAWWQEVNTLAMPMATPPTPPTARPGASPTPAC         
              360       370       380       390                 

>>CCDS65042.1 PAX5 gene_id:5079|Hs108|chr9                (319 aa)
 initn: 557 init1: 531 opt: 582  Z-score: 458.3  bits: 93.1 E(32554): 3.3e-19
Smith-Waterman score: 582; 40.5% identity (64.5% similar) in 279 aa overlap (1-271:20-284)

                                  10        20        30        40 
pF1KE0                    MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV
                          .:::::.::::::::  .::.::.:: .:.::::::: :.:
CCDS65 MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
               10        20        30        40        50        60

              50        60        70        80        90       100 
pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA
       :.:::::::::::.:: ..:  ::::::..::: :: .::. : . :..:::::. .: :
CCDS65 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA
               70        80        90       100       110       120

             110       120          130       140         150      
pF1KE0 EGLCTQDKTPSVSSINRVLRA-LQE--DQGLPCTRLRSPAVLAPAVLTPHS--GSETPRG
       : .: .: .::::::::..:. .:.  .: .: .  .: ..    : . ::  : .  : 
CCDS65 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASS-HSIGIQESPVPNGHSLPGRDFLRK
              130       140       150        160       170         

        160       170       180       190       200       210      
pF1KE0 THPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAK
          :       .:. .: :.:.. :.: .: :  .    .:    ::.:..  .:   . 
CCDS65 QMRGD------LFTQQQLEVLDRVFERQHYSDIFT----TTEPIKPEQTTE--YSAMASL
     180             190       200           210       220         

        220       230          240       250       260       270   
pF1KE0 WRRQEKLKWEMQLPG-ASQGLTVP--RVAPGIISAQQSPGSVPTAALPALEPLGPSCYQL
           . .: ..  :  :. : .::  .  : . . . .  ..:    : . : : . :  
CCDS65 AGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYP-PHVPPAGQGSYSA
       230       240       250       260       270        280      

           280       290       300       310       320       330   
pF1KE0 CWATAPERCLSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLW
                                                                   
CCDS65 PTLTGMVPGSPYYYSAAARGAAPPAAATAYDRH                           
        290       300       310                                    

>>CCDS42735.1 PAX8 gene_id:7849|Hs108|chr2                (287 aa)
 initn: 604 init1: 533 opt: 566  Z-score: 446.7  bits: 90.8 E(32554): 1.5e-18
Smith-Waterman score: 566; 39.1% identity (64.6% similar) in 274 aa overlap (1-268:13-274)

                           10        20        30        40        
pF1KE0             MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK
                   .::::: ::::::::  .::.:: :: .:.::::::: :.::.:::::
CCDS42 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD
       ::::::.:: ..:  ::::::..::: :: .:.. : . :..:::::. .: :::.: .:
CCDS42 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

      110       120        130       140        150          160   
pF1KE0 KTPSVSSINRVLRA-LQEDQGLPCTRLRSPAVLAPA-VLTPHSG---SETPRGTHPGTGH
        .::::::::..:. .:.  .::     .   :.:. .: : :.    :.:..   :. .
CCDS42 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

           170       180       190       200        210       220  
pF1KE0 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRV-WFSNRRAKWRRQEK
           ... .:  . ..... ..  .        ...: :.  .:.  ::        :..
CCDS42 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFS--------QHH
              190       200       210       220               230  

            230       240       250       260       270       280  
pF1KE0 LKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWATAPERC
       :.  .. :   :      ..:.  ...:    : : :.:   :  :              
CCDS42 LE-PLECPFERQHYPEAYASPSHTKGEQE---VNTLAMPMATPPTPPTARPGASPTPAC 
             240       250       260          270       280        

            290       300       310       320       330       340  
pF1KE0 LSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLLYGL

>>CCDS41561.1 PAX2 gene_id:5076|Hs108|chr10               (394 aa)
 initn: 637 init1: 550 opt: 565  Z-score: 444.4  bits: 90.9 E(32554): 2e-18
Smith-Waterman score: 565; 39.6% identity (64.9% similar) in 285 aa overlap (1-280:20-291)

                                  10        20        30        40 
pF1KE0                    MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV
                          .:::::.::::::::  .::.::.:: .:.::::::: :.:
CCDS41 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
               10        20        30        40        50        60

              50        60        70        80        90       100 
pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA
       :.:::::::::::.:: ..:  ::::::..::: :: .::. : . :..:::::. .: :
CCDS41 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
               70        80        90       100       110       120

             110       120       130       140        150       160
pF1KE0 EGLCTQDKTPSVSSINRVLRALQEDQGLPCTRLRSPAVLAPA-VLTPHSGSETPRGTHPG
       ::.: .: .::::::::..:.  ..   :     . .: ::. ...: ..:  :    : 
CCDS41 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTAS--P----PV
              130       140       150       160       170          

              170          180       190       200        210      
pF1KE0 TGHRNRTIFSPSQAEAL---EKEFQRGQYPDSVARGKLATATSLPE-DTVRVWFSNRRAK
       ..  :  . : :    :   ... .. .  ..:..:.. .. :    :..:  .      
CCDS41 SSASNDPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFT
          180       190       200       210       220       230    

        220       230       240       250       260       270      
pF1KE0 WRRQEKLKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSCYQLCWA
        .. : :   .. :.  .   : ...  : : : .  :.: :  :.:. .  :   :  .
CCDS41 QQQLEALDRVFERPSYPD---VFQASEHIKSEQGNEYSLP-ALTPGLDEVKSS---LSAS
          240       250          260       270        280          

        280       290       300       310       320       330      
pF1KE0 TAPERCLSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGC
       : ::                                                        
CCDS41 TNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGN
       290       300       310       320       330       340       

>>CCDS7499.1 PAX2 gene_id:5076|Hs108|chr10                (396 aa)
 initn: 658 init1: 550 opt: 565  Z-score: 444.4  bits: 90.9 E(32554): 2e-18
Smith-Waterman score: 596; 35.4% identity (58.6% similar) in 362 aa overlap (1-300:20-373)

                                  10        20        30        40 
pF1KE0                    MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKV
                          .:::::.::::::::  .::.::.:: .:.::::::: :.:
CCDS74 MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV
               10        20        30        40        50        60

              50        60        70        80        90       100 
pF1KE0 SNGCVSKILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCA
       :.:::::::::::.:: ..:  ::::::..::: :: .::. : . :..:::::. .: :
CCDS74 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLA
               70        80        90       100       110       120

             110       120       130             140         150   
pF1KE0 EGLCTQDKTPSVSSINRVLRALQEDQGLPC-----TRLRSPA-VLAPAVLTP--HSGSET
       ::.: .: .::::::::..:.  ..   :      : . .:. ...:.. .:   :.:. 
CCDS74 EGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASND
              130       140       150       160       170       180

           160                                            170      
pF1KE0 PRGTHPGTG------------HRNRTI-------------------------FSPSQAEA
       : :..  .:            .:.. .                         :. .: ::
CCDS74 PVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEA
              190       200       210       220       230       240

        180       190            200            210       220      
pF1KE0 LEKEFQRGQYPDSVA-----RGKLATATSLPE-----DTVRVWFSNRRAKWRRQEKLKWE
       :.. :.: .:::        ... ..  :::      : :.  .:      .   ...  
CCDS74 LDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNP-ELGSNVSGT
              250       260       270       280       290          

        230           240       250       260          270         
pF1KE0 MQLPGAS----QGLTVPRVAPGIISAQQSPGSVPTAALPALEP---LGPSCYQLCWATAP
       .  : ..     . :.:   : .  . :  :: ::..: .. :   .:::   .   . :
CCDS74 QTYPVVTGRDMASTTLPGYPPHVPPTGQ--GSYPTSTLAGMVPEAAVGPSSSLM---SKP
     300       310       320         330       340       350       

     280       290       300       310       320       330         
pF1KE0 ERCLSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPGCPLL
        : :...::  :..:  .  :                                       
CCDS74 GRKLAEVPP--CVQPTGASSPATRTATPSTRPTTRLGDSATPPY                
          360         370       380       390                      

>>CCDS42736.1 PAX8 gene_id:7849|Hs108|chr2                (321 aa)
 initn: 604 init1: 533 opt: 558  Z-score: 440.1  bits: 89.8 E(32554): 3.4e-18
Smith-Waterman score: 565; 38.3% identity (62.4% similar) in 303 aa overlap (1-290:13-311)

                           10        20        30        40        
pF1KE0             MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK
                   .::::: ::::::::  .::.:: :: .:.::::::: :.::.:::::
CCDS42 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD
       ::::::.:: ..:  ::::::..::: :: .:.. : . :..:::::. .: :::.: .:
CCDS42 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

      110       120        130       140        150          160   
pF1KE0 KTPSVSSINRVLRA-LQEDQGLPCTRLRSPAVLAPA-VLTPHSG---SETPRGTHPGTGH
        .::::::::..:. .:.  .::     .   :.:. .: : :.    :.:..   :. .
CCDS42 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

           170       180       190       200        210            
pF1KE0 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRV-WFSNRRAK-----W
           ... .:  . ..... ..  .        ...: :.  .:.  ::... .     .
CCDS42 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240

       220       230       240       250       260       270       
pF1KE0 RRQEKLKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLGPSC--YQLCW
       .::.     .  :. ..:    :   :    .  : : : :   :. :: ::   .:   
CCDS42 ERQH-YPEAYASPSHTKGEQGERWW-GPRCPDTHPTS-PPADRAAMPPL-PSQAWWQEVN
               250       260        270        280        290      

         280       290       300       310       320       330     
pF1KE0 ATAPERCLSDTPPKACLKPCWGHLPPQPNSLDSGLLCLPCPSSHCPLASLSGSQALLWPG
       . :       ::: :                                             
CCDS42 TLAMPMATPPTPPTARPGASPTPAC                                   
        300       310       320                                    

>>CCDS46398.1 PAX8 gene_id:7849|Hs108|chr2                (450 aa)
 initn: 582 init1: 533 opt: 558  Z-score: 438.5  bits: 89.9 E(32554): 4.2e-18
Smith-Waterman score: 558; 50.6% identity (74.7% similar) in 178 aa overlap (1-173:13-190)

                           10        20        30        40        
pF1KE0             MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSK
                   .::::: ::::::::  .::.:: :: .:.::::::: :.::.:::::
CCDS46 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KE0 ILGRYYRTGVLEPKGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQD
       ::::::.:: ..:  ::::::..::: :: .:.. : . :..:::::. .: :::.: .:
CCDS46 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
               70        80        90       100       110       120

      110       120        130       140        150          160   
pF1KE0 KTPSVSSINRVLRA-LQEDQGLPCTRLRSPAVLAPA-VLTPHSG---SETPRGTHPGTGH
        .::::::::..:. .:.  .::     .   :.:. .: : :.    :.:..   :. .
CCDS46 TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KE0 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKL
           ... .:                                                  
CCDS46 SINGLLGIAQPGSDKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLECPF
              190       200       210       220       230       240




343 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:31:20 2016 done: Sat Nov  5 04:31:21 2016
 Total Scan time:  3.010 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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