Result of FASTA (omim) for pF1KE0738
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0738, 424 aa
  1>>>pF1KE0738 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0223+/-0.000341; mu= 19.4940+/- 0.021
 mean_var=104.9378+/-25.580, 0's: 0 Z-trim(116.2): 527  B-trim: 2879 in 2/48
 Lambda= 0.125201
 statistics sampled from 26407 (27157) to 26407 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.318), width:  16
 Scan time:  9.370

The best scores are:                                      opt bits E(85289)
NP_000698 (OMIM: 600264) vasopressin V1b receptor  ( 424) 2883 531.7 1.4e-150
NP_000697 (OMIM: 600821) vasopressin V1a receptor  ( 418) 1252 237.1 6.5e-62
NP_000907 (OMIM: 167055) oxytocin receptor [Homo s ( 389)  812 157.6 5.2e-38
XP_011532064 (OMIM: 167055) PREDICTED: oxytocin re ( 389)  812 157.6 5.2e-38
NP_001139623 (OMIM: 300538,300539,304800) vasopres ( 309)  668 131.4 3.1e-30
NP_000045 (OMIM: 300538,300539,304800) vasopressin ( 371)  668 131.5 3.4e-30
XP_006724891 (OMIM: 300538,300539,304800) PREDICTE ( 371)  668 131.5 3.4e-30
NP_997055 (OMIM: 608584,608595) neuropeptide S rec ( 371)  415 85.8   2e-16
NP_997056 (OMIM: 608584,608595) neuropeptide S rec ( 377)  415 85.8   2e-16
NP_001287864 (OMIM: 608584,608595) neuropeptide S  ( 390)  415 85.8   2e-16
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444)  355 75.1   4e-13
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461)  355 75.1 4.1e-13
NP_000397 (OMIM: 138850,146110) gonadotropin-relea ( 328)  335 71.3 4.1e-12
NP_001287862 (OMIM: 608584,608595) neuropeptide S  ( 366)  329 70.3 9.2e-12
NP_000612 (OMIM: 103780,164230,181500,182135,60678 ( 471)  327 70.1 1.4e-11
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389)  325 69.6 1.6e-11
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425)  319 68.6 3.6e-11
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425)  319 68.6 3.6e-11
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425)  319 68.6 3.6e-11
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447)  318 68.4 4.2e-11
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516)  318 68.5 4.5e-11
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389)  305 66.0 1.9e-10
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392)  305 66.0 1.9e-10
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397)  305 66.0   2e-10
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400)  305 66.0   2e-10
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403)  305 66.0   2e-10
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406)  305 66.0   2e-10
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414)  305 66.0   2e-10
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418)  305 66.0   2e-10
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420)  305 66.0   2e-10
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520)  306 66.3 2.1e-10
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446)  305 66.0 2.1e-10
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493)  305 66.1 2.3e-10
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493)  305 66.1 2.3e-10
XP_016874005 (OMIM: 118445) PREDICTED: gastrin/cho ( 381)  287 62.7 1.8e-09
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370)  286 62.5   2e-09
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin  ( 370)  286 62.5   2e-09
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370)  286 62.5   2e-09
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370)  286 62.5   2e-09
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin  ( 388)  286 62.5 2.1e-09
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin  ( 388)  286 62.5 2.1e-09
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin  ( 388)  286 62.5 2.1e-09
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399)  286 62.6 2.1e-09
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465)  285 62.5 2.7e-09
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348)  282 61.8 3.2e-09
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384)  282 61.8 3.4e-09
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384)  282 61.8 3.4e-09
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365)  280 61.4 4.3e-09
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin  ( 365)  280 61.4 4.3e-09
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479)  281 61.8 4.5e-09


>>NP_000698 (OMIM: 600264) vasopressin V1b receptor [Hom  (424 aa)
 initn: 2883 init1: 2883 opt: 2883  Z-score: 2824.6  bits: 531.7 E(85289): 1.4e-150
Smith-Waterman score: 2883; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)

               10        20        30        40        50        60
pF1KE0 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
              370       380       390       400       410       420

           
pF1KE0 TIIF
       ::::
NP_000 TIIF
           

>>NP_000697 (OMIM: 600821) vasopressin V1a receptor [Hom  (418 aa)
 initn: 1257 init1: 844 opt: 1252  Z-score: 1232.5  bits: 237.1 E(85289): 6.5e-62
Smith-Waterman score: 1254; 51.4% identity (75.5% similar) in 383 aa overlap (2-377:14-386)

                               10        20         30        40   
pF1KE0             MDSGPLWD----ANPTPRGTLSAPNATTPWLG-RDEELAKVEIGVLAT
                    .:.: :     :. : : . .  ... :    :.:::::.::.:::.
NP_000 MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KE0 VLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGP
       ....:. :: .:::.: .  :: ::::::. ::.:.:::::.::::::. :::::::.::
NP_000 TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KE0 DLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAI
       : :::.::.:::..::::.:::..:: :::.::::::..::::.. . :.::: :.:. .
NP_000 DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KE0 FSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLIC
       .: :: :.::. :: . . . :::: :  ::: :::.:: : .::: ::..: .::..::
NP_000 LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
              190       200       210       220       230       240

           230       240       250       260         270       280 
pF1KE0 HEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRG--LPSRVSSINTISRAKIRTVK
       ..:  :.. :: . .  :         . .. .:  .:  :   :::...::::::::::
NP_000 YNIWCNVRGKTASRQSKG---------AEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVK
              250                260       270       280       290 

             290       300       310       320       330       340 
pF1KE0 MTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGF
       :::::: :::.:::::: .:::::::  .   .: : ..::. :::.::::::::::: :
NP_000 MTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFF
             300       310       320       330       340       350 

             350       360       370       380       390       400 
pF1KE0 NSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRP
       ..:::   .. . :: . . .. .. .: :.: :.:                        
NP_000 SGHLLQDCVQSFPCCQNMKEKFNKEDTD-SMSRRQTFYSNNRSPTNSTGMWKDSPKSSKS
             360       370        380       390       400       410

             410       420    
pF1KE0 RPEESPRDLELADGEGTAETIIF
                              
NP_000 IKFIPVST               
                              

>>NP_000907 (OMIM: 167055) oxytocin receptor [Homo sapie  (389 aa)
 initn: 1154 init1: 494 opt: 812  Z-score: 803.3  bits: 157.6 E(85289): 5.2e-38
Smith-Waterman score: 1224; 52.3% identity (75.5% similar) in 371 aa overlap (8-378:15-368)

                      10        20        30        40        50   
pF1KE0        MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNL
                     .:. .: :. .  .:  :   :.: ::.::..::  .:.:: .:: 
NP_000 MEGALAANWSAEAANASAAPPGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNA
               10        20        30          40        50        

            60        70        80        90       100       110   
pF1KE0 AVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYL
        :::.:    .:.::. .:. ::...::.::.::::::::::::.:: ::::::: ::::
NP_000 CVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYL
       60        70        80        90       100       110        

           120       130       140       150       160       170   
pF1KE0 QVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFS
       ::..::::::.:: :.::: ::.:.:::::..  ..  : . : ::   . : ::: :::
NP_000 QVVGMFASTYLLLLMSLDRCLAICQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFS
      120       130       140       150         160       170      

           180       190       200       210       220       230   
pF1KE0 LREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVK
       ::::  ..::.:::: :  ::::.::.:: :::....:: .:.:::.::  .: .::..:
NP_000 LREV--ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLK
        180         190       200       210       220       230    

           240       250       260       270       280       290   
pF1KE0 TQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIAC
       : :  ..       . :  .. .   :   .::::.. ::.::::::::::.::::.:.:
NP_000 TAAAAAA-------EAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVC
          240              250       260       270       280       

           300       310       320       330       340       350   
pF1KE0 WAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHL
       :.::: :::::::: ::: : :   :: : :::..::::::::::: :..::. . ....
NP_000 WTPFFFVQMWSVWDANAPKEAS---AFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRF
       290       300          310       320       330       340    

           360       370       380       390       400       410   
pF1KE0 ACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
        ::..   . :: :.. : :.. ..                                   
NP_000 LCCSASYLKGRR-LGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA              
          350        360       370       380                       

>>XP_011532064 (OMIM: 167055) PREDICTED: oxytocin recept  (389 aa)
 initn: 1154 init1: 494 opt: 812  Z-score: 803.3  bits: 157.6 E(85289): 5.2e-38
Smith-Waterman score: 1224; 52.3% identity (75.5% similar) in 371 aa overlap (8-378:15-368)

                      10        20        30        40        50   
pF1KE0        MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNL
                     .:. .: :. .  .:  :   :.: ::.::..::  .:.:: .:: 
XP_011 MEGALAANWSAEAANASAAPPGAEGNRTAGPP--RRNEALARVEVAVLCLILLLALSGNA
               10        20        30          40        50        

            60        70        80        90       100       110   
pF1KE0 AVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYL
        :::.:    .:.::. .:. ::...::.::.::::::::::::.:: ::::::: ::::
XP_011 CVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYL
       60        70        80        90       100       110        

           120       130       140       150       160       170   
pF1KE0 QVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFS
       ::..::::::.:: :.::: ::.:.:::::..  ..  : . : ::   . : ::: :::
XP_011 QVVGMFASTYLLLLMSLDRCLAICQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFS
      120       130       140       150         160       170      

           180       190       200       210       220       230   
pF1KE0 LREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVK
       ::::  ..::.:::: :  ::::.::.:: :::....:: .:.:::.::  .: .::..:
XP_011 LREV--ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLK
        180         190       200       210       220       230    

           240       250       260       270       280       290   
pF1KE0 TQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIAC
       : :  ..       . :  .. .   :   .::::.. ::.::::::::::.::::.:.:
XP_011 TAAAAAA-------EAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVC
          240              250       260       270       280       

           300       310       320       330       340       350   
pF1KE0 WAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHL
       :.::: :::::::: ::: : :   :: : :::..::::::::::: :..::. . ....
XP_011 WTPFFFVQMWSVWDANAPKEAS---AFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRF
       290       300          310       320       330       340    

           360       370       380       390       400       410   
pF1KE0 ACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
        ::..   . :: :.. : :.. ..                                   
XP_011 LCCSASYLKGRR-LGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA              
          350        360       370       380                       

>>NP_001139623 (OMIM: 300538,300539,304800) vasopressin   (309 aa)
 initn: 821 init1: 352 opt: 668  Z-score: 663.9  bits: 131.4 E(85289): 3.1e-30
Smith-Waterman score: 811; 44.3% identity (68.6% similar) in 309 aa overlap (10-313:13-303)

                  10        20        30        40        50       
pF1KE0    MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLL
                   .:.  .  :  .   :   ::  ::..:...:. :.: .. .:  :: 
NP_001 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
               10        20        30        40        50        60

        60          70        80        90       100       110     
pF1KE0 TLGQLGRKR--SRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQV
       .:.. ::.   . .:.:. :: :.::::::::::::: :  : ::.::: :::::::::.
NP_001 ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
               70        80        90       100       110       120

         120       130       140       150          160       170  
pF1KE0 LSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTY---LLIAAPWLLAAIFSLPQVFIF
       ..:.::.::.:::::::. :.:.:. . .. . . .   .:.:  : .. ..::::.:::
NP_001 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVA--WAFSLLLSLPQLFIF
              130       140       150       160         170        

            180       190       200       210       220       230  
pF1KE0 SLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKV
       . :.:  :::: :::: :. ::: :.:.:: .: .:: :.  ..::  :: .::  .: :
NP_001 AQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL-V
      180       190       200       210       220       230        

            240       250       260       270       280       290  
pF1KE0 KTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIA
          . : ::   :   : .         : :.. . .   : :  .::.::.:::..:. 
NP_001 PGPSERPGG---RRRGRRT---------GSPGEGAHV---SAAVAKTVRMTLVIVVVYVL
       240          250                260          270       280  

            300       310       320       330       340       350  
pF1KE0 CWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRH
       :::::: ::.:..:: .:: :                                       
NP_001 CWAPFFLVQLWAAWDPEAPLEGGCSRG                                 
            290       300                                          

>>NP_000045 (OMIM: 300538,300539,304800) vasopressin V2   (371 aa)
 initn: 931 init1: 352 opt: 668  Z-score: 663.0  bits: 131.5 E(85289): 3.4e-30
Smith-Waterman score: 933; 44.4% identity (67.4% similar) in 356 aa overlap (10-361:13-348)

                  10        20        30        40        50       
pF1KE0    MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLL
                   .:.  .  :  .   :   ::  ::..:...:. :.: .. .:  :: 
NP_000 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
               10        20        30        40        50        60

        60          70        80        90       100       110     
pF1KE0 TLGQLGRKR--SRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQV
       .:.. ::.   . .:.:. :: :.::::::::::::: :  : ::.::: :::::::::.
NP_000 ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
               70        80        90       100       110       120

         120       130       140        150       160       170    
pF1KE0 LSMFASTYMLLAMTLDRYLAVCHPLRSLQQ-PGQSTYLLIAAPWLLAAIFSLPQVFIFSL
       ..:.::.::.:::::::. :.:.:. . ..  :      . . : .. ..::::.:::. 
NP_000 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
              130       140       150       160       170       180

          180       190       200       210       220       230    
pF1KE0 REVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKT
       :.:  :::: :::: :. ::: :.:.:: .: .:: :.  ..::  :: .::  .: :  
NP_000 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL-VPG
              190       200       210       220       230          

          240       250       260       270       280       290    
pF1KE0 QAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACW
        . : ::   :   : .         : :.. . .   : :  .::.::.:::..:. ::
NP_000 PSERPGG---RRRGRRT---------GSPGEGAHV---SAAVAKTVRMTLVIVVVYVLCW
     240          250                260          270       280    

          300       310       320       330       340       350    
pF1KE0 APFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLA
       :::: ::.:..:: .:: :   .. :.. :::..:::: ::::: .:.: .    :: : 
NP_000 APFFLVQLWAAWDPEAPLE---GAPFVLLMLLASLNSCTNPWIYASFSSSV-SSELRSLL
          290       300          310       320       330        340

           360       370       380       390       400       410   
pF1KE0 CCG-GPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
       ::. :  :                                                    
NP_000 CCARGRTPPSLGPQDESCTTASSSLAKDTSS                             
              350       360       370                              

>>XP_006724891 (OMIM: 300538,300539,304800) PREDICTED: v  (371 aa)
 initn: 931 init1: 352 opt: 668  Z-score: 663.0  bits: 131.5 E(85289): 3.4e-30
Smith-Waterman score: 933; 44.4% identity (67.4% similar) in 356 aa overlap (10-361:13-348)

                  10        20        30        40        50       
pF1KE0    MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLL
                   .:.  .  :  .   :   ::  ::..:...:. :.: .. .:  :: 
XP_006 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
               10        20        30        40        50        60

        60          70        80        90       100       110     
pF1KE0 TLGQLGRKR--SRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQV
       .:.. ::.   . .:.:. :: :.::::::::::::: :  : ::.::: :::::::::.
XP_006 ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
               70        80        90       100       110       120

         120       130       140        150       160       170    
pF1KE0 LSMFASTYMLLAMTLDRYLAVCHPLRSLQQ-PGQSTYLLIAAPWLLAAIFSLPQVFIFSL
       ..:.::.::.:::::::. :.:.:. . ..  :      . . : .. ..::::.:::. 
XP_006 VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
              130       140       150       160       170       180

          180       190       200       210       220       230    
pF1KE0 REVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKT
       :.:  :::: :::: :. ::: :.:.:: .: .:: :.  ..::  :: .::  .: :  
XP_006 RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASL-VPG
              190       200       210       220       230          

          240       250       260       270       280       290    
pF1KE0 QAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACW
        . : ::   :   : .         : :.. . .   : :  .::.::.:::..:. ::
XP_006 PSERPGG---RRRGRRT---------GSPGEGAHV---SAAVAKTVRMTLVIVVVYVLCW
     240          250                260          270       280    

          300       310       320       330       340       350    
pF1KE0 APFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLA
       :::: ::.:..:: .:: :   .. :.. :::..:::: ::::: .:.: .    :: : 
XP_006 APFFLVQLWAAWDPEAPLE---GAPFVLLMLLASLNSCTNPWIYASFSSSV-SSELRSLL
          290       300          310       320       330        340

           360       370       380       390       400       410   
pF1KE0 CCG-GPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
       ::. :  :                                                    
XP_006 CCARGRTPPSLGPQDESCTTASSSLAKDTSS                             
              350       360       370                              

>>NP_997055 (OMIM: 608584,608595) neuropeptide S recepto  (371 aa)
 initn: 477 init1: 267 opt: 415  Z-score: 416.0  bits: 85.8 E(85289): 2e-16
Smith-Waterman score: 539; 30.4% identity (63.4% similar) in 352 aa overlap (3-345:15-337)

                           10           20        30        40     
pF1KE0             MDSGPLWDANP---TPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL
                     .:   :..:   :   :..       : .    .   .. .: ...
NP_997 MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KE0 VLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDL
       :..  :: .::..  .  .:.::: .:: .::.::  ..: ..: .. : .:  : .:::
NP_997 VFTIVGNSVVLFSTWRR-KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDL
               70         80        90       100       110         

         110       120       130       140       150       160     
pF1KE0 LCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFS
       .::.:.::::. ..::::.:.....::: :. .:.. ::   :.  :.. : : :. .::
NP_997 VCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA-WSLSFLFS
     120       130       140       150       160       170         

         170       180          190       200       210       220  
pF1KE0 LPQVFIFSLREVIQGSGVLDCWA---DFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLI
       .: ..::. : .  ..: ..:::   : .. : :  :.: ... .. .:.:...  :...
NP_997 IPTLIIFGKRTL--SNGEVQCWALWPDDSY-WTP--YMTIVAFLVYFIPLTIISIMYGIV
      180       190         200          210       220       230   

            230       240       250        260       270       280 
pF1KE0 CHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAAT-TRGLPSRVSSINTISRAKIRTVK
            ... .:......      . .  : . : .. .:::         ::.:::...:
NP_997 ----IRTIWIKSKTYET------VISNCSDGKLCSSYNRGL---------ISKAKIKAIK
               240             250       260                270    

             290       300       310         320       330         
pF1KE0 MTFVIVLAYIACWAPFFSVQMWSVWDKNA--PDEDSTNVAFTISMLLGNLNSCCNPWIYM
       ....:.::.: ::.:.:   .... :.    :: .    : .: . :  :::  :: :: 
NP_997 YSIIIILAFICCWSPYF---LFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYC
          280       290          300       310       320       330 

     340       350       360       370       380       390         
pF1KE0 GFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSG
        :.: .                                                      
NP_997 VFSSSISFPCREQRSQDSRMTFRERTERHEMQILSKPEFI                    
             340       350       360       370                     

>>NP_997056 (OMIM: 608584,608595) neuropeptide S recepto  (377 aa)
 initn: 477 init1: 267 opt: 415  Z-score: 415.9  bits: 85.8 E(85289): 2e-16
Smith-Waterman score: 539; 30.4% identity (63.4% similar) in 352 aa overlap (3-345:15-337)

                           10           20        30        40     
pF1KE0             MDSGPLWDANP---TPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL
                     .:   :..:   :   :..       : .    .   .. .: ...
NP_997 MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KE0 VLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDL
       :..  :: .::..  .  .:.::: .:: .::.::  ..: ..: .. : .:  : .:::
NP_997 VFTIVGNSVVLFSTWRR-KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDL
               70         80        90       100       110         

         110       120       130       140       150       160     
pF1KE0 LCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFS
       .::.:.::::. ..::::.:.....::: :. .:.. ::   :.  :.. : : :. .::
NP_997 VCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA-WSLSFLFS
     120       130       140       150       160       170         

         170       180          190       200       210       220  
pF1KE0 LPQVFIFSLREVIQGSGVLDCWA---DFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLI
       .: ..::. : .  ..: ..:::   : .. : :  :.: ... .. .:.:...  :...
NP_997 IPTLIIFGKRTL--SNGEVQCWALWPDDSY-WTP--YMTIVAFLVYFIPLTIISIMYGIV
      180       190         200          210       220       230   

            230       240       250        260       270       280 
pF1KE0 CHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAAT-TRGLPSRVSSINTISRAKIRTVK
            ... .:......      . .  : . : .. .:::         ::.:::...:
NP_997 ----IRTIWIKSKTYET------VISNCSDGKLCSSYNRGL---------ISKAKIKAIK
               240             250       260                270    

             290       300       310         320       330         
pF1KE0 MTFVIVLAYIACWAPFFSVQMWSVWDKNA--PDEDSTNVAFTISMLLGNLNSCCNPWIYM
       ....:.::.: ::.:.:   .... :.    :: .    : .: . :  :::  :: :: 
NP_997 YSIIIILAFICCWSPYF---LFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYC
          280       290          300       310       320       330 

     340       350       360       370       380       390         
pF1KE0 GFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSG
        :.: .                                                      
NP_997 VFSSSISFPCRVIRLRQLQEAALMLCPQRENWKGTWPGVPSWALPR              
             340       350       360       370                     

>>NP_001287864 (OMIM: 608584,608595) neuropeptide S rece  (390 aa)
 initn: 493 init1: 283 opt: 415  Z-score: 415.8  bits: 85.8 E(85289): 2e-16
Smith-Waterman score: 539; 30.4% identity (63.4% similar) in 352 aa overlap (3-345:15-337)

                           10           20        30        40     
pF1KE0             MDSGPLWDANP---TPRGTLSAPNATTPWLGRDEELAKVEIGVLATVL
                     .:   :..:   :   :..       : .    .   .. .: ...
NP_001 MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
               10        20        30        40        50        60

          50        60        70        80        90       100     
pF1KE0 VLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDL
       :..  :: .::..  .  .:.::: .:: .::.::  ..: ..: .. : .:  : .:::
NP_001 VFTIVGNSVVLFSTWRR-KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDL
               70         80        90       100       110         

         110       120       130       140       150       160     
pF1KE0 LCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFS
       .::.:.::::. ..::::.:.....::: :. .:.. ::   :.  :.. : : :. .::
NP_001 VCRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIA-WSLSFLFS
     120       130       140       150       160       170         

         170       180          190       200       210       220  
pF1KE0 LPQVFIFSLREVIQGSGVLDCWA---DFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLI
       .: ..::. : .  ..: ..:::   : .. : :  :.: ... .. .:.:...  :...
NP_001 IPTLIIFGKRTL--SNGEVQCWALWPDDSY-WTP--YMTIVAFLVYFIPLTIISIMYGIV
      180       190         200          210       220       230   

            230       240       250        260       270       280 
pF1KE0 CHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAAT-TRGLPSRVSSINTISRAKIRTVK
            ... .:......      . .  : . : .. .:::         ::.:::...:
NP_001 ----IRTIWIKSKTYET------VISNCSDGKLCSSYNRGL---------ISKAKIKAIK
               240             250       260                270    

             290       300       310         320       330         
pF1KE0 MTFVIVLAYIACWAPFFSVQMWSVWDKNA--PDEDSTNVAFTISMLLGNLNSCCNPWIYM
       ....:.::.: ::.:.:   .... :.    :: .    : .: . :  :::  :: :: 
NP_001 YSIIIILAFICCWSPYF---LFDILDNFNLLPDTQERFYASVIIQNLPALNSAINPLIYC
          280       290          300       310       320       330 

     340       350       360       370       380       390         
pF1KE0 GFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSG
        :.: .                                                      
NP_001 VFSSSISFPCRANSSVYLLACDVSVLWALVLTSEKESCESWRRKGAKITGFQNDVPGEN 
             340       350       360       370       380       390 




424 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 04:23:34 2016 done: Sat Nov  5 04:23:36 2016
 Total Scan time:  9.370 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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