Result of FASTA (ccds) for pF1KE0676
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0676, 396 aa
  1>>>pF1KE0676 396 - 396 aa - 396 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.3262+/-0.00113; mu= 6.8654+/- 0.066
 mean_var=155.3411+/-35.567, 0's: 0 Z-trim(106.2): 99  B-trim: 115 in 1/49
 Lambda= 0.102904
 statistics sampled from 8750 (8847) to 8750 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.272), width:  16
 Scan time:  2.500

The best scores are:                                      opt bits E(32554)
CCDS9947.1 VRK1 gene_id:7443|Hs108|chr14           ( 396) 2664 407.9  8e-114
CCDS46291.1 VRK2 gene_id:7444|Hs108|chr2           ( 396) 1152 183.5   3e-46
CCDS1859.1 VRK2 gene_id:7444|Hs108|chr2            ( 508) 1152 183.6 3.6e-46
CCDS46292.1 VRK2 gene_id:7444|Hs108|chr2           ( 485) 1121 178.9 8.5e-45
CCDS33076.1 VRK3 gene_id:51231|Hs108|chr19         ( 424)  733 121.3 1.7e-27
CCDS12791.1 VRK3 gene_id:51231|Hs108|chr19         ( 474)  733 121.3 1.8e-27
CCDS77334.1 VRK3 gene_id:51231|Hs108|chr19         ( 412)  659 110.3 3.3e-24
CCDS11806.1 CSNK1D gene_id:1453|Hs108|chr17        ( 409)  427 75.8 7.7e-14
CCDS11805.1 CSNK1D gene_id:1453|Hs108|chr17        ( 415)  427 75.9 7.8e-14
CCDS13970.1 CSNK1E gene_id:1454|Hs108|chr22        ( 416)  419 74.7 1.8e-13
CCDS47303.1 CSNK1A1 gene_id:1452|Hs108|chr5        ( 337)  401 71.9 9.7e-13
CCDS64291.1 CSNK1A1 gene_id:1452|Hs108|chr5        ( 325)  398 71.5 1.3e-12
CCDS9363.1 CSNK1A1L gene_id:122011|Hs108|chr13     ( 337)  385 69.5   5e-12
CCDS59491.1 CSNK1G3 gene_id:1456|Hs108|chr5        ( 424)  383 69.3 7.4e-12
CCDS10192.2 CSNK1G1 gene_id:53944|Hs108|chr15      ( 422)  382 69.2 8.1e-12
CCDS4135.1 CSNK1G3 gene_id:1456|Hs108|chr5         ( 447)  376 68.3 1.6e-11
CCDS43355.1 CSNK1G3 gene_id:1456|Hs108|chr5        ( 455)  376 68.3 1.6e-11
CCDS59492.1 CSNK1G3 gene_id:1456|Hs108|chr5        ( 348)  374 67.9 1.6e-11
CCDS34218.1 CSNK1G3 gene_id:1456|Hs108|chr5        ( 423)  374 68.0 1.9e-11
CCDS12077.1 CSNK1G2 gene_id:1455|Hs108|chr19       ( 415)  373 67.8   2e-11
CCDS59493.1 CSNK1G3 gene_id:1456|Hs108|chr5        ( 311)  369 67.1 2.5e-11


>>CCDS9947.1 VRK1 gene_id:7443|Hs108|chr14                (396 aa)
 initn: 2664 init1: 2664 opt: 2664  Z-score: 2156.9  bits: 407.9 E(32554): 8e-114
Smith-Waterman score: 2664; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)

               10        20        30        40        50        60
pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK
              310       320       330       340       350       360

              370       380       390      
pF1KE0 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK
       ::::::::::::::::::::::::::::::::::::
CCDS99 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK
              370       380       390      

>>CCDS46291.1 VRK2 gene_id:7444|Hs108|chr2                (396 aa)
 initn: 1150 init1: 729 opt: 1152  Z-score: 943.8  bits: 183.5 E(32554): 3e-46
Smith-Waterman score: 1152; 55.4% identity (79.0% similar) in 314 aa overlap (12-324:4-313)

               10        20        30        40        50          
pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSS
                  . . : .:   :  :... ::  ..: .:  ::.:::: ::::   :. 
CCDS46         MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKP
                       10        20        30        40        50  

      60        70        80        90       100       110         
pF1KE0 ESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLH
       :.   ::  ::::: ..:::::.:::::::.:: . :.:::. ..: :::.: ..:::: 
CCDS46 EK---DARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLT
                60        70        80        90       100         

     120       130       140       150       160       170         
pF1KE0 DKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIK
       . .:.:::::.:.:.: :::::   :.  :...:::::..:.::.::::::.::::::::
CCDS46 EFKGRSYRFMVMERLGIDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIK
     110       120       130        140       150       160        

     180       190       200       210       220       230         
pF1KE0 ASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPS
       :.::::.:::::::::.::::.:::::.: ::.:.:.:.. :.:::::::.:::.::: :
CCDS46 AANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALS
      170       180       190       200       210       220        

     240       250       260       270       280       290         
pF1KE0 RRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEI
       ::.:.:::::::..:: :.::::.:::::  :. .:    ... . . :  :  ..  ::
CCDS46 RRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEI
      230       240       250       260       270       280        

     300       310       320       330       340       350         
pF1KE0 AKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRK
       :...  .. : : ::: :. :. ::                                   
CCDS46 AQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAA
      290       300       310       320       330       340        

>>CCDS1859.1 VRK2 gene_id:7444|Hs108|chr2                 (508 aa)
 initn: 1183 init1: 729 opt: 1152  Z-score: 942.3  bits: 183.6 E(32554): 3.6e-46
Smith-Waterman score: 1163; 47.3% identity (71.4% similar) in 406 aa overlap (12-396:4-405)

               10        20        30        40        50          
pF1KE0 MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSS
                  . . : .:   :  :... ::  ..: .:  ::.:::: ::::   :. 
CCDS18         MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKP
                       10        20        30        40        50  

      60        70        80        90       100       110         
pF1KE0 ESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLH
       :.   ::  ::::: ..:::::.:::::::.:: . :.:::. ..: :::.: ..:::: 
CCDS18 EK---DARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLT
                60        70        80        90       100         

     120       130       140       150       160       170         
pF1KE0 DKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIK
       . .:.:::::.:.:.: :::::   :.  :...:::::..:.::.::::::.::::::::
CCDS18 EFKGRSYRFMVMERLGIDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIK
     110       120       130        140       150       160        

     180       190       200       210       220       230         
pF1KE0 ASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPS
       :.::::.:::::::::.::::.:::::.: ::.:.:.:.. :.:::::::.:::.::: :
CCDS18 AANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALS
      170       180       190       200       210       220        

     240       250       260       270       280       290         
pF1KE0 RRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEI
       ::.:.:::::::..:: :.::::.:::::  :. .:    ... . . :  :  ..  ::
CCDS18 RRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEI
      230       240       250       260       270       280        

     300       310       320       330       340                350
pF1KE0 AKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLK
       :...  .. : : ::: :. :. ::      .:  : .    :.         :..    
CCDS18 AQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAA
      290       300       310       320       330       340        

              360         370        380               390         
pF1KE0 AKTITKKRKKEIEES--KEPGVED-TEWSNTQTE--------EAIQTRSRTRKRVQK   
       .: ..: ... ::..  .: ..:. . :.  . :        :: :  .: :.. :.   
CCDS18 TKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQE
      350       360       370       380       390       400        

CCDS18 PLNEVNSFPQKISYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESST
      410       420       430       440       450       460        

>>CCDS46292.1 VRK2 gene_id:7444|Hs108|chr2                (485 aa)
 initn: 1157 init1: 729 opt: 1121  Z-score: 917.7  bits: 178.9 E(32554): 8.5e-45
Smith-Waterman score: 1132; 48.4% identity (72.3% similar) in 386 aa overlap (32-396:1-382)

              10        20        30        40        50         60
pF1KE0 PRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSSE
                                     :  ..: .:  ::.:::: ::::   :. :
CCDS46                               MEGNQWVLGKKIGSGGFGLIYLAFPTNKPE
                                             10        20        30

               70        80        90       100       110       120
pF1KE0 SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD
       .   ::  ::::: ..:::::.:::::::.:: . :.:::. ..: :::.: ..:::: .
CCDS46 K---DARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTE
                  40        50        60        70        80       

              130       140       150       160       170       180
pF1KE0 KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA
        .:.:::::.:.:.: :::::   :.  :...:::::..:.::.::::::.:::::::::
CCDS46 FKGRSYRFMVMERLGIDLQKISGQNGT-FKKSTVLQLGIRMLDVLEYIHENEYVHGDIKA
        90       100       110        120       130       140      

              190       200       210       220       230       240
pF1KE0 SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR
       .::::.:::::::::.::::.:::::.: ::.:.:.:.. :.:::::::.:::.::: ::
CCDS46 ANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSR
        150       160       170       180       190       200      

              250       260       270       280       290       300
pF1KE0 RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA
       :.:.:::::::..:: :.::::.:::::  :. .:    ... . . :  :  ..  :::
CCDS46 RSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIA
        210       220       230       240       250       260      

              310       320       330       340                350 
pF1KE0 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSV---------VENGGLKA
       ...  .. : : ::: :. :. ::      .:  : .    :.         :..    .
CCDS46 QFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAAT
        270       280       290       300       310       320      

             360         370        380               390          
pF1KE0 KTITKKRKKEIEES--KEPGVED-TEWSNTQTE--------EAIQTRSRTRKRVQK    
       : ..: ... ::..  .: ..:. . :.  . :        :: :  .: :.. :.    
CCDS46 KQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEP
        330       340       350       360       370       380      

CCDS46 LNEVNSFPQKISYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTG
        390       400       410       420       430       440      

>>CCDS33076.1 VRK3 gene_id:51231|Hs108|chr19              (424 aa)
 initn: 659 init1: 502 opt: 733  Z-score: 607.2  bits: 121.3 E(32554): 1.7e-27
Smith-Waterman score: 733; 36.2% identity (65.3% similar) in 334 aa overlap (5-329:85-411)

                                         10        20        30    
pF1KE0                           MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAK
                                     .. :. ..: .   : : . .: ..:: . 
CCDS33 PKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSL-EALPTGTVLTDKSG
           60        70        80        90        100       110   

           40        50        60           70        80        90 
pF1KE0 KEWKVGLPIGQGGFGCIYLADMNSSESVGSDAP---CVVKVEPSDNGPLFTELKFYQRAA
       ..::.     . . : .: :  .:. .  :        .:.. .: : ::.: .:.::::
CCDS33 RQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKD-GRLFNEQNFFQRAA
           120       130       140       150        160       170  

             100       110        120       130       140          
pF1KE0 KPEQIQKWIRTRKLKYLGVPKYWGSGLH-DKNGKSYRFMIMDRFGSDLQKIYEANAKR-F
       :: :..:: .  .   :..:   : :.: ::    :::...  .: .::.  ... :. .
CCDS33 KPLQVNKWKKLYSTPLLAIPTCMGFGVHQDK----YRFLVLPSLGRSLQSALDVSPKHVL
            180       190       200           210       220        

     150       160       170       180       190       200         
pF1KE0 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGV
       :...:::.. :.:: ::..::.:::::.. : :.... .. .:: :. ::.:.:::: : 
CCDS33 SERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGK
      230       240       250       260       270       280        

     210       220       230       240       250       260         
pF1KE0 HKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPK
       :  : :  .  :.: .:: :.: :.: .::::.::. :::::..:: : ::: . : . .
CCDS33 HVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTE
      290       300       310       320       330       340        

     270       280       290        300       310       320        
pF1KE0 YVRDSKIRYRENIASLMDKCFPEKNKPGE-IAKYMETVKLLDYTEKPLYENLRD---ILL
        .  .: .. .. . ..  :  .  .:.: . ::...:  : : ::: :  ::.    ::
CCDS33 DIMKQKQKFVDKPGPFVGPC-GHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALL
      350       360        370       380       390       400       

         330       340       350       360       370       380     
pF1KE0 QGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKKEIEESKEPGVEDTEWSNTQTEEAIQ
       : :.                                                        
CCDS33 QDLRVSPYDPIGLPMVP                                           
       410       420                                               

>>CCDS12791.1 VRK3 gene_id:51231|Hs108|chr19              (474 aa)
 initn: 659 init1: 502 opt: 733  Z-score: 606.5  bits: 121.3 E(32554): 1.8e-27
Smith-Waterman score: 733; 36.2% identity (65.3% similar) in 334 aa overlap (5-329:135-461)

                                         10        20        30    
pF1KE0                           MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAK
                                     .. :. ..: .   : : . .: ..:: . 
CCDS12 PKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSL-EALPTGTVLTDKSG
          110       120       130       140        150       160   

           40        50        60           70        80        90 
pF1KE0 KEWKVGLPIGQGGFGCIYLADMNSSESVGSDAP---CVVKVEPSDNGPLFTELKFYQRAA
       ..::.     . . : .: :  .:. .  :        .:.. .: : ::.: .:.::::
CCDS12 RQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKD-GRLFNEQNFFQRAA
           170       180       190       200        210       220  

             100       110        120       130       140          
pF1KE0 KPEQIQKWIRTRKLKYLGVPKYWGSGLH-DKNGKSYRFMIMDRFGSDLQKIYEANAKR-F
       :: :..:: .  .   :..:   : :.: ::    :::...  .: .::.  ... :. .
CCDS12 KPLQVNKWKKLYSTPLLAIPTCMGFGVHQDK----YRFLVLPSLGRSLQSALDVSPKHVL
            230       240       250           260       270        

     150       160       170       180       190       200         
pF1KE0 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGV
       :...:::.. :.:: ::..::.:::::.. : :.... .. .:: :. ::.:.:::: : 
CCDS12 SERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGK
      280       290       300       310       320       330        

     210       220       230       240       250       260         
pF1KE0 HKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPK
       :  : :  .  :.: .:: :.: :.: .::::.::. :::::..:: : ::: . : . .
CCDS12 HVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTE
      340       350       360       370       380       390        

     270       280       290        300       310       320        
pF1KE0 YVRDSKIRYRENIASLMDKCFPEKNKPGE-IAKYMETVKLLDYTEKPLYENLRD---ILL
        .  .: .. .. . ..  :  .  .:.: . ::...:  : : ::: :  ::.    ::
CCDS12 DIMKQKQKFVDKPGPFVGPC-GHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALL
      400       410        420       430       440       450       

         330       340       350       360       370       380     
pF1KE0 QGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKKEIEESKEPGVEDTEWSNTQTEEAIQ
       : :.                                                        
CCDS12 QDLRVSPYDPIGLPMVP                                           
       460       470                                               

>>CCDS77334.1 VRK3 gene_id:51231|Hs108|chr19              (412 aa)
 initn: 596 init1: 439 opt: 659  Z-score: 548.0  bits: 110.3 E(32554): 3.3e-24
Smith-Waterman score: 659; 37.3% identity (66.7% similar) in 276 aa overlap (5-275:135-404)

                                         10        20        30    
pF1KE0                           MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAK
                                     .. :. ..: .   : : . .: ..:: . 
CCDS77 PKSSPQKTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSL-EALPTGTVLTDKSG
          110       120       130       140        150       160   

           40        50        60           70        80        90 
pF1KE0 KEWKVGLPIGQGGFGCIYLADMNSSESVGSDAP---CVVKVEPSDNGPLFTELKFYQRAA
       ..::.     . . : .: :  .:. .  :        .:.. .: : ::.: .:.::::
CCDS77 RQWKLKSFQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKD-GRLFNEQNFFQRAA
           170       180       190       200        210       220  

             100       110        120       130       140          
pF1KE0 KPEQIQKWIRTRKLKYLGVPKYWGSGLH-DKNGKSYRFMIMDRFGSDLQKIYEANAKR-F
       :: :..:: .  .   :..:   : :.: ::    :::...  .: .::.  ... :. .
CCDS77 KPLQVNKWKKLYSTPLLAIPTCMGFGVHQDK----YRFLVLPSLGRSLQSALDVSPKHVL
            230       240       250           260       270        

     150       160       170       180       190       200         
pF1KE0 SRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGV
       :...:::.. :.:: ::..::.:::::.. : :.... .. .:: :. ::.:.:::: : 
CCDS77 SERSVLQVACRLLDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGK
      280       290       300       310       320       330        

     210       220       230       240       250       260         
pF1KE0 HKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPK
       :  : :  .  :.: .:: :.: :.: .::::.::. :::::..:: : ::: . : . .
CCDS77 HVAYVEGSRSPHEGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTE
      340       350       360       370       380       390        

     270       280       290       300       310       320         
pF1KE0 YVRDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLK
        .  .:                                                      
CCDS77 DIMKQKQKLPWDSF                                              
      400       410                                                

>>CCDS11806.1 CSNK1D gene_id:1453|Hs108|chr17             (409 aa)
 initn: 331 init1: 188 opt: 427  Z-score: 361.9  bits: 75.8 E(32554): 7.7e-14
Smith-Waterman score: 471; 29.6% identity (59.3% similar) in 334 aa overlap (37-364:9-313)

         10        20        30        40        50         60     
pF1KE0 AQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSSESVGSD
                                     ...:  ::.:.:: :::. :. ..: :.  
CCDS11                       MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIK
                                     10        20        30        

          70        80        90       100       110        120    
pF1KE0 APCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKY-WGSGLHDKNGK
         ::   .:.    :  : :.:.      ..:  .        :.:   : ..  :    
CCDS11 LECVKTKHPQ----LHIESKIYK------MMQGGV--------GIPTIRWCGAEGD----
       40            50              60                70          

          130       140       150       160       170       180    
pF1KE0 SYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLL
        :  :.:. .: .:. ...  ...:: :::: :. .... .:::: ....: :.: .:.:
CCDS11 -YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFL
          80        90       100       110       120       130     

           190       200       210       220       230       240   
pF1KE0 LNY-KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD
       ..  :. . ::..:.::: .:    .:..     ..   :: ...::..: :.  ::: :
CCDS11 MGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD
         140       150       160       170       180       190     

           250       260          270       280       290       300
pF1KE0 LEILGYCMIQWLTGHLPWED---NLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA
       :: ::: .. .  : :::.      :  :: : :. ..   :  :   :   :. :.:.:
CCDS11 LESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL---C---KGYPSEFA
         200       210       220       230       240               

              310       320       330       340       350       360
pF1KE0 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK
        :..  . : . .:: :  ::... . ..  : . :  .: .... :. .:   ......
CCDS11 TYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERR
     250       260       270       280       290       300         

              370       380       390                              
pF1KE0 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK                        
       . ::                                                        
CCDS11 DREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKV
     310       320       330       340       350       360         

>>CCDS11805.1 CSNK1D gene_id:1453|Hs108|chr17             (415 aa)
 initn: 331 init1: 188 opt: 427  Z-score: 361.8  bits: 75.9 E(32554): 7.8e-14
Smith-Waterman score: 471; 29.6% identity (59.3% similar) in 334 aa overlap (37-364:9-313)

         10        20        30        40        50         60     
pF1KE0 AQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DMNSSESVGSD
                                     ...:  ::.:.:: :::. :. ..: :.  
CCDS11                       MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIK
                                     10        20        30        

          70        80        90       100       110        120    
pF1KE0 APCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKY-WGSGLHDKNGK
         ::   .:.    :  : :.:.      ..:  .        :.:   : ..  :    
CCDS11 LECVKTKHPQ----LHIESKIYK------MMQGGV--------GIPTIRWCGAEGD----
       40            50              60                70          

          130       140       150       160       170       180    
pF1KE0 SYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLL
        :  :.:. .: .:. ...  ...:: :::: :. .... .:::: ....: :.: .:.:
CCDS11 -YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFL
          80        90       100       110       120       130     

           190       200       210       220       230       240   
pF1KE0 LNY-KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRGD
       ..  :. . ::..:.::: .:    .:..     ..   :: ...::..: :.  ::: :
CCDS11 MGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD
         140       150       160       170       180       190     

           250       260          270       280       290       300
pF1KE0 LEILGYCMIQWLTGHLPWED---NLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA
       :: ::: .. .  : :::.      :  :: : :. ..   :  :   :   :. :.:.:
CCDS11 LESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL---C---KGYPSEFA
         200       210       220       230       240               

              310       320       330       340       350       360
pF1KE0 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK
        :..  . : . .:: :  ::... . ..  : . :  .: .... :. .:   ......
CCDS11 TYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERR
     250       260       270       280       290       300         

              370       380       390                              
pF1KE0 EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK                        
       . ::                                                        
CCDS11 DREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKV
     310       320       330       340       350       360         

>>CCDS13970.1 CSNK1E gene_id:1454|Hs108|chr22             (416 aa)
 initn: 339 init1: 188 opt: 419  Z-score: 355.4  bits: 74.7 E(32554): 1.8e-13
Smith-Waterman score: 476; 29.4% identity (59.1% similar) in 340 aa overlap (36-369:8-318)

          10        20        30        40        50         60    
pF1KE0 AAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYL-ADMNSSESVGS
                                     ....:  ::.:.:: ::: :.. :.: :. 
CCDS13                        MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAI
                                      10        20        30       

           70        80        90       100       110        120   
pF1KE0 DAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKY-WGSGLHDKNG
          ::   .:.    :  : :::.      ..:  .        :.:.  : ..  :   
CCDS13 KLECVKTKHPQ----LHIESKFYK------MMQGGV--------GIPSIKWCGAEGD---
        40            50              60                70         

           130       140       150       160       170       180   
pF1KE0 KSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNL
         :  :.:. .: .:. ...  ...:: :::: :. .... .:::: ....: :.: .:.
CCDS13 --YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNF
           80        90       100       110       120       130    

            190       200       210       220       230       240  
pF1KE0 LLNY-KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSRRG
       :..  :. . ::..:.::: .:    .:..     ..   :: ...::..: :.  ::: 
CCDS13 LMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRD
          140       150       160       170       180       190    

            250       260          270       280       290         
pF1KE0 DLEILGYCMIQWLTGHLPWED---NLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEI
       ::: ::: .. .  : :::.      :  :: : :. ..   :  :   :   :. :.:.
CCDS13 DLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL---C---KGYPSEF
          200       210       220       230       240              

     300       310       320       330       340       350         
pF1KE0 AKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRK
       . :..  . : . .:: :  ::... . ..  : . :  .: .... :. .    . ...
CCDS13 STYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRER
      250       260       270       280       290       300        

     360       370       380       390                             
pF1KE0 KEIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK                       
       .: :. .. :                                                  
CCDS13 REHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAGNTSPRAIS
      310       320       330       340       350       360        




396 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 17:56:47 2016 done: Wed Nov  2 17:56:47 2016
 Total Scan time:  2.500 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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