Result of FASTA (omim) for pF1KE0661
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0661, 236 aa
  1>>>pF1KE0661 236 - 236 aa - 236 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6948+/-0.000507; mu= 11.4998+/- 0.032
 mean_var=289.1153+/-70.360, 0's: 0 Z-trim(116.0): 160  B-trim: 3130 in 2/56
 Lambda= 0.075429
 statistics sampled from 26584 (26774) to 26584 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.314), width:  16
 Scan time:  3.780

The best scores are:                                      opt bits E(85289)
NP_059965 (OMIM: 612428) RNA-binding protein 38 is ( 239)  871 107.8 1.7e-23
NP_906270 (OMIM: 612428) RNA-binding protein 38 is ( 121)  599 77.7 9.6e-15
NP_001278709 (OMIM: 612428) RNA-binding protein 38 ( 271)  538 71.7 1.4e-12
XP_011527187 (OMIM: 612428) PREDICTED: RNA-binding ( 247)  366 52.9 5.9e-07
XP_005260503 (OMIM: 612428) PREDICTED: RNA-binding ( 153)  342 49.9 2.8e-06
XP_011522588 (OMIM: 607897) PREDICTED: RNA-binding ( 242)  255 40.8  0.0025
XP_016879638 (OMIM: 607897) PREDICTED: RNA-binding ( 259)  255 40.9  0.0026
NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324)  255 41.0  0.0029
XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346)  255 41.1   0.003
XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346)  255 41.1   0.003
XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343)  252 40.7  0.0038
XP_016879636 (OMIM: 607897) PREDICTED: RNA-binding ( 315)  248 40.2  0.0049


>>NP_059965 (OMIM: 612428) RNA-binding protein 38 isofor  (239 aa)
 initn: 950 init1: 790 opt: 871  Z-score: 543.0  bits: 107.8 E(85289): 1.7e-23
Smith-Waterman score: 984; 68.1% identity (79.4% similar) in 238 aa overlap (1-236:24-239)

                                      10        20        30       
pF1KE0                        MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
                              :: .:::::.:::::::::::::::::::::: ::.:
NP_059 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
               10        20        30        40        50        60

        40        50        60        70        80        90       
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: .: 
NP_059 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQT
               70        80        90       100       110       120

       100       110       120       130       140       150       
pF1KE0 GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGA--
       :::.:::::::.:::: .:.  ::.:: :.:::.:::: . :. . .:  :::.:: :  
NP_059 GFAIGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIP-AAPVPSLSS--PYIEYTPASP
              130       140       150        160         170       

         160       170       180       190       200       210     
pF1KE0 AYAQYSAAAAAAAAAAAYDQYPYAASPAAAGYVTAGGYGYAVQQPITAAAPGTAAAAAAA
       :::::  :.        :::::::::::.:.  .. .:  :: : ..::::         
NP_059 AYAQYPPAT--------YDQYPYAASPATAASFVGYSYPAAVPQALSAAAP---------
       180               190       200       210       220         

         220       230      
pF1KE0 AAAAAAFGQYQPQQLQTDRMQ
         :...: :::  ::: ::::
NP_059 --AGTTFVQYQAPQLQPDRMQ
                230         

>>NP_906270 (OMIM: 612428) RNA-binding protein 38 isofor  (121 aa)
 initn: 599 init1: 599 opt: 599  Z-score: 385.7  bits: 77.7 E(85289): 9.6e-15
Smith-Waterman score: 599; 91.8% identity (95.9% similar) in 98 aa overlap (1-98:24-121)

                                      10        20        30       
pF1KE0                        MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
                              :: .:::::.:::::::::::::::::::::: ::.:
NP_906 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
               10        20        30        40        50        60

        40        50        60        70        80        90       
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRIMQP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: .: 
NP_906 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQT
               70        80        90       100       110       120

       100       110       120       130       140       150       
pF1KE0 GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGAAY
       :                                                           
NP_906 G                                                           
                                                                   

>>NP_001278709 (OMIM: 612428) RNA-binding protein 38 iso  (271 aa)
 initn: 936 init1: 451 opt: 538  Z-score: 346.6  bits: 71.7 E(85289): 1.4e-12
Smith-Waterman score: 910; 60.0% identity (70.0% similar) in 270 aa overlap (1-236:24-271)

                                      10        20        30       
pF1KE0                        MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
                              :: .:::::.:::::::::::::::::::::: ::.:
NP_001 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
               10        20        30        40        50        60

        40        50                                        60     
pF1KE0 EEAVVITDRQTGKSRGYGF--------------------------------VTMADRAAA
       :::::::::::::::::::                                :::::::::
NP_001 EEAVVITDRQTGKSRGYGFGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAA
               70        80        90       100       110       120

          70        80        90       100       110       120     
pF1KE0 ERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQ
       :::::::::::::::::::::::::::: .: :::.:::::::.:::: .:.  ::.:: 
NP_001 ERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGLTPHYIYPP
              130       140       150       160       170       180

         130       140       150         160       170       180   
pF1KE0 AFVQPGVVIPHVQPTAAAASTTPYIDYTGA--AYAQYSAAAAAAAAAAAYDQYPYAASPA
       :.:::.:::: . :. . .:  :::.:: :  :::::  :.        :::::::::::
NP_001 AIVQPSVVIP-AAPVPSLSS--PYIEYTPASPAYAQYPPAT--------YDQYPYAASPA
              190          200       210               220         

           190       200       210       220       230      
pF1KE0 AAGYVTAGGYGYAVQQPITAAAPGTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ
       .:.  .. .:  :: : ..::::           :...: :::  ::: ::::
NP_001 TAASFVGYSYPAAVPQALSAAAP-----------AGTTFVQYQAPQLQPDRMQ
     230       240       250                  260       270 

>>XP_011527187 (OMIM: 612428) PREDICTED: RNA-binding pro  (247 aa)
 initn: 685 init1: 360 opt: 366  Z-score: 245.8  bits: 52.9 E(85289): 5.9e-07
Smith-Waterman score: 625; 70.3% identity (75.0% similar) in 148 aa overlap (1-116:24-171)

                                      10        20        30       
pF1KE0                        MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
                              :: .:::::.:::::::::::::::::::::: ::.:
XP_011 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
               10        20        30        40        50        60

        40        50                                        60     
pF1KE0 EEAVVITDRQTGKSRGYGF--------------------------------VTMADRAAA
       :::::::::::::::::::                                :::::::::
XP_011 EEAVVITDRQTGKSRGYGFGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAA
               70        80        90       100       110       120

          70        80        90       100       110       120     
pF1KE0 ERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQ
       :::::::::::::::::::::::::::: .: :::.:::::::.:::: .:         
XP_011 ERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGRKMEVFTEA
              130       140       150       160       170       180

         130       140       150       160       170       180     
pF1KE0 AFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAAAAAAAAAAAYDQYPYAASPAAA
                                                                   
XP_011 TTGFHLSLTGHNWVTGHGHHRGSEMRRQAPRTPECQADPALHLPTSHRAAQRGDPSRPCP
              190       200       210       220       230       240

>>XP_005260503 (OMIM: 612428) PREDICTED: RNA-binding pro  (153 aa)
 initn: 585 init1: 339 opt: 342  Z-score: 233.6  bits: 49.9 E(85289): 2.8e-06
Smith-Waterman score: 525; 69.2% identity (72.3% similar) in 130 aa overlap (1-98:24-153)

                                      10        20        30       
pF1KE0                        MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
                              :: .:::::.:::::::::::::::::::::: ::.:
XP_005 MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDI
               10        20        30        40        50        60

        40        50                                        60     
pF1KE0 EEAVVITDRQTGKSRGYGF--------------------------------VTMADRAAA
       :::::::::::::::::::                                :::::::::
XP_005 EEAVVITDRQTGKSRGYGFGIIFVLEGHISQALNFDGRSWNPGGIFVGEPQVTMADRAAA
               70        80        90       100       110       120

          70        80        90       100       110       120     
pF1KE0 ERACKDPNPIIDGRKANVNLAYLGAKPRIMQPGFAFGVQQLHPALIQRPFGIPAHYVYPQ
       :::::::::::::::::::::::::::: .: :                           
XP_005 ERACKDPNPIIDGRKANVNLAYLGAKPRSLQTG                           
              130       140       150                              

         130       140       150       160       170       180     
pF1KE0 AFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAAAAAAAAAAAYDQYPYAASPAAA

>>XP_011522588 (OMIM: 607897) PREDICTED: RNA-binding pro  (242 aa)
 initn: 305 init1: 189 opt: 255  Z-score: 180.6  bits: 40.8 E(85289): 0.0025
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:3-212)

               10        20        30        40        50        60
pF1KE0 MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEIEEAVVITDRQTGKSRGYGFVTMA
              :   :::::::  .:.  ....::: ::..:.:... :. :.. ::.::::. 
XP_011      MVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFE
                    10        20        30        40        50     

               70        80        90            100       110     
pF1KE0 DRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQP----GFAFGVQQLHPALIQRPF
       .. ..:..:.     :... .. .     :.:. .: :    : : :.     :..   .
XP_011 NEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMFPPGTRGRARGLPYTMDAFM---L
          60        70            80        90       100           

         120       130       140       150       160       170     
pF1KE0 GIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAAAAAAAAAAAYDQ
       :. .   ::.  .  :   :   :. .      .  . .:::.  .:::.::: ... ..
XP_011 GM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGFPAAAYGPVAAAAVAAARGSVLNS
      110        120       130           140       150       160   

               180       190       200       210       220         
pF1KE0 Y---PY---AASPAAAGYVTAGGYGYAVQQPITAAAPGTAAAAAAAAAAAAAFGQYQPQQ
       :   :     ::::... .  ::.      :  : .:: .:   . :.  .. :.:    
XP_011 YSAQPNFGAPASPAGSNPARPGGF------P-GANSPGPVADLYGPASQDSGVGNYISAA
           170       180              190       200       210      

     230                         
pF1KE0 LQTDRMQ                   
                                 
XP_011 SPQPGSGFGHGIAGPLIATAFTNGYH
        220       230       240  

>>XP_016879638 (OMIM: 607897) PREDICTED: RNA-binding pro  (259 aa)
 initn: 305 init1: 189 opt: 255  Z-score: 180.4  bits: 40.9 E(85289): 0.0026
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:20-229)

                           10        20        30        40        
pF1KE0             MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEIEEAVVITDRQT
                          :   :::::::  .:.  ....::: ::..:.:... :. :
XP_016 MTAGLRAELSGDAGPLKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTT
               10        20        30        40        50        60

       50        60        70        80        90            100   
pF1KE0 GKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQP----GFAFGV
       .. ::.::::. .. ..:..:.     :... .. .     :.:. .: :    : : :.
XP_016 NRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMFPPGTRGRARGL
               70        80        90           100       110      

           110       120       130       140       150       160   
pF1KE0 QQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAA
            :..   .:. .   ::.  .  :   :   :. .      .  . .:::.  .::
XP_016 PYTMDAFM---LGM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGFPAAAYGPVAAA
        120           130       140       150           160        

           170             180       190       200       210       
pF1KE0 AAAAAAAAAYDQY---PY---AASPAAAGYVTAGGYGYAVQQPITAAAPGTAAAAAAAAA
       :.::: ... ..:   :     ::::... .  ::.      :  : .:: .:   . :.
XP_016 AVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGF------P-GANSPGPVADLYGPAS
      170       180       190       200              210       220 

       220       230                         
pF1KE0 AAAAFGQYQPQQLQTDRMQ                   
         .. :.:                              
XP_016 QDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH
             230       240       250         

>>NP_001309179 (OMIM: 607897) RNA-binding protein Musash  (324 aa)
 initn: 305 init1: 189 opt: 255  Z-score: 179.5  bits: 41.0 E(85289): 0.0029
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:85-294)

                                      10        20        30       
pF1KE0                        MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
                                     :   :::::::  .:.  ....::: ::..
NP_001 KVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKV
           60        70        80        90       100       110    

        40        50        60        70        80        90       
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQ
       :.:... :. :.. ::.::::. .. ..:..:.     :... .. .     :.:. .: 
NP_001 EDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMF
          120       130       140       150       160           170

            100       110       120       130       140       150  
pF1KE0 P----GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDY
       :    : : :.     :..   .:. .   ::.  .  :   :   :. .      .  .
NP_001 PPGTRGRARGLPYTMDAFM---LGM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGF
              180          190        200       210           220  

            160       170             180       190       200      
pF1KE0 TGAAYAQYSAAAAAAAAAAAYDQY---PY---AASPAAAGYVTAGGYGYAVQQPITAAAP
        .:::.  .:::.::: ... ..:   :     ::::... .  ::.      :  : .:
NP_001 PAAAYGPVAAAAVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGF------P-GANSP
            230       240       250       260             270      

        210       220       230                         
pF1KE0 GTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ                   
       : .:   . :.  .. :.:                              
NP_001 GPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH
         280       290       300       310       320    

>>XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding pro  (346 aa)
 initn: 305 init1: 189 opt: 255  Z-score: 179.2  bits: 41.1 E(85289): 0.003
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:107-316)

                                      10        20        30       
pF1KE0                        MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
                                     :   :::::::  .:.  ....::: ::..
XP_005 KVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKV
         80        90       100       110       120       130      

        40        50        60        70        80        90       
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQ
       :.:... :. :.. ::.::::. .. ..:..:.     :... .. .     :.:. .: 
XP_005 EDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMF
        140       150       160       170       180           190  

            100       110       120       130       140       150  
pF1KE0 P----GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDY
       :    : : :.     :..   .:. .   ::.  .  :   :   :. .      .  .
XP_005 PPGTRGRARGLPYTMDAFM---LGM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGF
            200       210           220       230       240        

            160       170             180       190       200      
pF1KE0 TGAAYAQYSAAAAAAAAAAAYDQY---PY---AASPAAAGYVTAGGYGYAVQQPITAAAP
        .:::.  .:::.::: ... ..:   :     ::::... .  ::.      :  : .:
XP_005 PAAAYGPVAAAAVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGF------P-GANSP
          250       260       270       280       290              

        210       220       230                         
pF1KE0 GTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ                   
       : .:   . :.  .. :.:                              
XP_005 GPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH
       300       310       320       330       340      

>>XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding pro  (346 aa)
 initn: 305 init1: 189 opt: 255  Z-score: 179.2  bits: 41.1 E(85289): 0.003
Smith-Waterman score: 255; 28.8% identity (57.6% similar) in 229 aa overlap (8-225:107-316)

                                      10        20        30       
pF1KE0                        MHTTQKDTTYTKIFVGGLPYHTTDASLRKYFEVFGEI
                                     :   :::::::  .:.  ....::: ::..
XP_005 KVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKV
         80        90       100       110       120       130      

        40        50        60        70        80        90       
pF1KE0 EEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPR-IMQ
       :.:... :. :.. ::.::::. .. ..:..:.     :... .. .     :.:. .: 
XP_005 EDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECK----KAQPKEVMF
        140       150       160       170       180           190  

            100       110       120       130       140       150  
pF1KE0 P----GFAFGVQQLHPALIQRPFGIPAHYVYPQAFVQPGVVIPHVQPTAAAASTTPYIDY
       :    : : :.     :..   .:. .   ::.  .  :   :   :. .      .  .
XP_005 PPGTRGRARGLPYTMDAFM---LGM-GMLGYPNFVATYGRGYPGFAPSYGYQ----FPGF
            200       210           220       230       240        

            160       170             180       190       200      
pF1KE0 TGAAYAQYSAAAAAAAAAAAYDQY---PY---AASPAAAGYVTAGGYGYAVQQPITAAAP
        .:::.  .:::.::: ... ..:   :     ::::... .  ::.      :  : .:
XP_005 PAAAYGPVAAAAVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGF------P-GANSP
          250       260       270       280       290              

        210       220       230                         
pF1KE0 GTAAAAAAAAAAAAAFGQYQPQQLQTDRMQ                   
       : .:   . :.  .. :.:                              
XP_005 GPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIASIPGCPGKTGRSF
       300       310       320       330       340      




236 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:33:33 2016 done: Wed Nov  2 18:33:34 2016
 Total Scan time:  3.780 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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