Result of FASTA (omim) for pF1KE3228
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3228, 520 aa
  1>>>pF1KE3228     520 - 520 aa - 520 aa
Library: /omim/omim.rfq.tfa
  65951994 residues in 93482 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0481+/-0.00033; mu= 15.5829+/- 0.021
 mean_var=92.9775+/-18.811, 0's: 0 Z-trim(116.1): 40  B-trim: 0 in 0/52
 Lambda= 0.133010
 statistics sampled from 28180 (28220) to 28180 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.302), width:  16
 Scan time:  4.880

The best scores are:                                      opt bits E(93482)
NP_004557 (OMIM: 605319) 6-phosphofructo-2-kinase/ ( 520) 3488 679.7 6.3e-195
NP_001350474 (OMIM: 605319) 6-phosphofructo-2-kina ( 568) 3402 663.2 6.3e-190
NP_001300992 (OMIM: 605319) 6-phosphofructo-2-kina ( 514) 3398 662.4 9.8e-190
NP_001138915 (OMIM: 605319) 6-phosphofructo-2-kina ( 500) 3310 645.5 1.2e-184
NP_001269559 (OMIM: 605319) 6-phosphofructo-2-kina ( 534) 3309 645.3 1.4e-184
XP_016871816 (OMIM: 605319) 6-phosphofructo-2-kina ( 548) 3224 629.0 1.2e-179
NP_001309945 (OMIM: 605319) 6-phosphofructo-2-kina ( 494) 3220 628.2 1.8e-179
XP_005252521 (OMIM: 605319) 6-phosphofructo-2-kina ( 462) 3003 586.6 5.9e-167
XP_016871818 (OMIM: 605319) 6-phosphofructo-2-kina ( 501) 2382 467.4 4.7e-131
XP_016871815 (OMIM: 605319) 6-phosphofructo-2-kina ( 549) 2296 451.0 4.7e-126
XP_024303424 (OMIM: 171835) 6-phosphofructo-2-kina ( 472) 2292 450.1 7.1e-126
NP_006203 (OMIM: 171835) 6-phosphofructo-2-kinase/ ( 505) 2292 450.2 7.5e-126
XP_024303422 (OMIM: 171835) 6-phosphofructo-2-kina ( 505) 2292 450.2 7.5e-126
XP_024303423 (OMIM: 171835) 6-phosphofructo-2-kina ( 505) 2292 450.2 7.5e-126
NP_001309946 (OMIM: 605319) 6-phosphofructo-2-kina ( 337) 2268 445.4 1.3e-124
XP_024303425 (OMIM: 171835) 6-phosphofructo-2-kina ( 471) 2231 438.4 2.4e-122
NP_001018063 (OMIM: 171835) 6-phosphofructo-2-kina ( 471) 2231 438.4 2.4e-122
NP_004558 (OMIM: 605320) 6-phosphofructo-2-kinase/ ( 469) 2230 438.2 2.7e-122
NP_002616 (OMIM: 311790) 6-phosphofructo-2-kinase/ ( 471) 2226 437.5 4.6e-122
XP_024303805 (OMIM: 605319) 6-phosphofructo-2-kina ( 385) 2182 429.0 1.4e-119
XP_011517795 (OMIM: 605319) 6-phosphofructo-2-kina ( 427) 2180 428.6 1.9e-119
XP_016871817 (OMIM: 605319) 6-phosphofructo-2-kina ( 533) 2180 428.7 2.3e-119
NP_001304064 (OMIM: 605320) 6-phosphofructo-2-kina ( 462) 2170 426.7 7.8e-119
XP_024308157 (OMIM: 311790) 6-phosphofructo-2-kina ( 448) 2167 426.1 1.1e-118
XP_011532131 (OMIM: 605320) 6-phosphofructo-2-kina ( 471) 2165 425.8 1.5e-118
NP_001304065 (OMIM: 605320) 6-phosphofructo-2-kina ( 458) 2163 425.4  2e-118
XP_024309363 (OMIM: 605320) 6-phosphofructo-2-kina ( 435) 2161 425.0 2.5e-118
XP_016862105 (OMIM: 605320) 6-phosphofructo-2-kina ( 457) 2161 425.0 2.6e-118
NP_001304063 (OMIM: 605320) 6-phosphofructo-2-kina ( 498) 2161 425.0 2.7e-118
XP_016862106 (OMIM: 605320) 6-phosphofructo-2-kina ( 453) 2159 424.6 3.3e-118
XP_016862103 (OMIM: 605320) 6-phosphofructo-2-kina ( 493) 2157 424.3 4.6e-118
XP_016885067 (OMIM: 311790) 6-phosphofructo-2-kina ( 449) 1955 385.5  2e-106
XP_016885065 (OMIM: 311790) 6-phosphofructo-2-kina ( 500) 1955 385.5 2.2e-106
NP_001258734 (OMIM: 311790) 6-phosphofructo-2-kina ( 406) 1941 382.8 1.2e-105
NP_001258733 (OMIM: 311790) 6-phosphofructo-2-kina ( 449) 1840 363.4 8.8e-100
XP_016885066 (OMIM: 311790) 6-phosphofructo-2-kina ( 468) 1702 336.9 8.5e-92
NP_001304066 (OMIM: 605320) 6-phosphofructo-2-kina ( 434) 1522 302.4   2e-81
XP_016862104 (OMIM: 605320) 6-phosphofructo-2-kina ( 463) 1453 289.1   2e-77
NP_001304067 (OMIM: 605320) 6-phosphofructo-2-kina ( 278) 1404 279.6 9.2e-75
XP_005273219 (OMIM: 171835) 6-phosphofructo-2-kina ( 263) 1193 239.1 1.4e-62


>>NP_004557 (OMIM: 605319) 6-phosphofructo-2-kinase/fruc  (520 aa)
 initn: 3488 init1: 3488 opt: 3488  Z-score: 3621.3  bits: 679.7 E(93482): 6.3e-195
Smith-Waterman score: 3488; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
              430       440       450       460       470       480

              490       500       510       520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
       ::::::::::::::::::::::::::::::::::::::::
NP_004 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
              490       500       510       520

>>NP_001350474 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (568 aa)
 initn: 3428 init1: 3401 opt: 3402  Z-score: 3531.5  bits: 663.2 E(93482): 6.3e-190
Smith-Waterman score: 3402; 98.4% identity (99.4% similar) in 515 aa overlap (1-515:1-515)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
              430       440       450       460       470       480

              490       500       510       520                    
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH                    
       :::::::::::::::::::::::::..:..  . :                         
NP_001 EHVASTSAALPSCLPPEVPTQLPGQELKSGIPGRDPEPPVQPPEGQSILWIPREVTVASR
              490       500       510       520       530       540

NP_001 SGPGAAPSIPEPRLVSLPHLSGSAASGS
              550       560        

>>NP_001300992 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (514 aa)
 initn: 3425 init1: 3398 opt: 3398  Z-score: 3528.0  bits: 662.4 E(93482): 9.8e-190
Smith-Waterman score: 3398; 99.4% identity (99.6% similar) in 509 aa overlap (1-509:1-509)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
              430       440       450       460       470       480

              490       500       510       520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
       ::::::::::::::::::::::::: . :           
NP_001 EHVASTSAALPSCLPPEVPTQLPGQPLLGQACLT      
              490       500       510          

>>NP_001138915 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (500 aa)
 initn: 3310 init1: 3310 opt: 3310  Z-score: 3436.9  bits: 645.5 E(93482): 1.2e-184
Smith-Waterman score: 3310; 99.6% identity (100.0% similar) in 496 aa overlap (25-520:5-500)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
                               ..::::::::::::::::::::::::::::::::::
NP_001                     MPFRKACGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
                                   10        20        30        40

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
              110       120       130       140       150       160

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
              170       180       190       200       210       220

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
              230       240       250       260       270       280

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
              290       300       310       320       330       340

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
              350       360       370       380       390       400

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
              410       420       430       440       450       460

              490       500       510       520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
       ::::::::::::::::::::::::::::::::::::::::
NP_001 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
              470       480       490       500

>>NP_001269559 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (534 aa)
 initn: 3307 init1: 3307 opt: 3309  Z-score: 3435.5  bits: 645.3 E(93482): 1.4e-184
Smith-Waterman score: 3309; 99.2% identity (99.6% similar) in 499 aa overlap (22-520:36-534)

                        10        20        30        40        50 
pF1KE3          MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYI
                                     :.  .:::::::::::::::::::::::::
NP_001 QKEGDSQQAGALPLLCQLDTFSPKATVFGVSINPACGPKLTNSPTVIVMVGLPARGKTYI
          10        20        30        40        50        60     

              60        70        80        90       100       110 
pF1KE3 SKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKLTRYLNWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVK
          70        80        90       100       110       120     

             120       130       140       150       160       170 
pF1KE3 SYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYLAKEGGQIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKIS
         130       140       150       160       170       180     

             180       190       200       210       220       230 
pF1KE3 SPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDYKDCNSAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHI
         190       200       210       220       230       240     

             240       250       260       270       280       290 
pF1KE3 QSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSRIVYYLMNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNL
         250       260       270       280       290       300     

             300       310       320       330       340       350 
pF1KE3 KDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLRVWTSQLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQD
         310       320       330       340       350       360     

             360       370       380       390       400       410 
pF1KE3 KYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYYYRYPTGESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLK
         370       380       390       400       410       420     

             420       430       440       450       460       470 
pF1KE3 CPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPLHTVLKLTPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPT
         430       440       450       460       470       480     

             480       490       500       510       520
pF1KE3 KKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKPRINSFEEHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
         490       500       510       520       530    

>>XP_016871816 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (548 aa)
 initn: 3246 init1: 3219 opt: 3224  Z-score: 3347.2  bits: 629.0 E(93482): 1.2e-179
Smith-Waterman score: 3224; 98.0% identity (99.4% similar) in 491 aa overlap (25-515:5-495)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
                               ..::::::::::::::::::::::::::::::::::
XP_016                     MPFRKACGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
                                   10        20        30        40

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
              110       120       130       140       150       160

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
              170       180       190       200       210       220

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
              230       240       250       260       270       280

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
              290       300       310       320       330       340

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
              350       360       370       380       390       400

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
              410       420       430       440       450       460

              490       500       510       520                    
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH                    
       :::::::::::::::::::::::::..:..  . :                         
XP_016 EHVASTSAALPSCLPPEVPTQLPGQELKSGIPGRDPEPPVQPPEGQSILWIPREVTVASR
              470       480       490       500       510       520

XP_016 SGPGAAPSIPEPRLVSLPHLSGSAASGS
              530       540        

>>NP_001309945 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (494 aa)
 initn: 3243 init1: 3216 opt: 3220  Z-score: 3343.7  bits: 628.2 E(93482): 1.8e-179
Smith-Waterman score: 3220; 99.0% identity (99.6% similar) in 485 aa overlap (25-509:5-489)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
                               ..::::::::::::::::::::::::::::::::::
NP_001                     MPFRKACGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
                                   10        20        30        40

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
              110       120       130       140       150       160

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
              170       180       190       200       210       220

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
              230       240       250       260       270       280

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
              290       300       310       320       330       340

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
              350       360       370       380       390       400

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
              410       420       430       440       450       460

              490       500       510       520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
       ::::::::::::::::::::::::: . :           
NP_001 EHVASTSAALPSCLPPEVPTQLPGQPLLGQACLT      
              470       480       490          

>>XP_005252521 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (462 aa)
 initn: 3030 init1: 3003 opt: 3003  Z-score: 3119.0  bits: 586.6 E(93482): 5.9e-167
Smith-Waterman score: 3003; 99.6% identity (99.8% similar) in 450 aa overlap (1-450:1-450)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       :::::::::::::::::::::::::::. :                              
XP_005 TPVAYGCRVESIYLNVESVCTHRERSENMKGSRSSADSSRKH                  
              430       440       450       460                    

>>XP_016871818 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (501 aa)
 initn: 2382 init1: 2382 opt: 2382  Z-score: 2474.5  bits: 467.4 E(93482): 4.7e-131
Smith-Waterman score: 3315; 96.3% identity (96.3% similar) in 520 aa overlap (1-520:1-501)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       :::::::::::::::::::::::::::                   ::::::::::::::
XP_016 IAVFDATNTTRERRHMILHFAKENDFK-------------------EVKISSPDYKDCNS
              130       140                          150       160 

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
             170       180       190       200       210       220 

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
             230       240       250       260       270       280 

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
             290       300       310       320       330       340 

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
             350       360       370       380       390       400 

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
             410       420       430       440       450       460 

              490       500       510       520
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
       ::::::::::::::::::::::::::::::::::::::::
XP_016 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH
             470       480       490       500 

>>XP_016871815 (OMIM: 605319) 6-phosphofructo-2-kinase/f  (549 aa)
 initn: 3265 init1: 2294 opt: 2296  Z-score: 2384.7  bits: 451.0 E(93482): 4.7e-126
Smith-Waterman score: 3229; 94.8% identity (95.7% similar) in 515 aa overlap (1-515:1-496)

               10        20        30        40        50        60
pF1KE3 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGGQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 IAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
       :::::::::::::::::::::::::::                   ::::::::::::::
XP_016 IAVFDATNTTRERRHMILHFAKENDFK-------------------EVKISSPDYKDCNS
              130       140                          150       160 

              190       200       210       220       230       240
pF1KE3 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
             170       180       190       200       210       220 

              250       260       270       280       290       300
pF1KE3 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQ
             230       240       250       260       270       280 

              310       320       330       340       350       360
pF1KE3 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
             290       300       310       320       330       340 

              370       380       390       400       410       420
pF1KE3 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
             350       360       370       380       390       400 

              430       440       450       460       470       480
pF1KE3 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPVAYGCRVESIYLNVESVCTHRERSEDAKKGPNPLMRRNSVTPLASPEPTKKPRINSFE
             410       420       430       440       450       460 

              490       500       510       520                    
pF1KE3 EHVASTSAALPSCLPPEVPTQLPGQNMKGSRSSADSSRKH                    
       :::::::::::::::::::::::::..:..  . :                         
XP_016 EHVASTSAALPSCLPPEVPTQLPGQELKSGIPGRDPEPPVQPPEGQSILWIPREVTVASR
             470       480       490       500       510       520 

XP_016 SGPGAAPSIPEPRLVSLPHLSGSAASGS
             530       540         




520 residues in 1 query   sequences
65951994 residues in 93482 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Jun 19 14:28:11 2019 done: Wed Jun 19 14:28:12 2019
 Total Scan time:  4.880 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
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