Result of FASTA (omim) for pF1KE0477
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0477, 305 aa
  1>>>pF1KE0477 305 - 305 aa - 305 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4033+/-0.000377; mu= 14.8386+/- 0.023
 mean_var=62.1491+/-12.961, 0's: 0 Z-trim(112.7): 16  B-trim: 0 in 0/50
 Lambda= 0.162688
 statistics sampled from 21655 (21661) to 21655 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.254), width:  16
 Scan time:  6.980

The best scores are:                                      opt bits E(85289)
NP_008834 (OMIM: 609988) inorganic pyrophosphatase ( 305) 2074 495.4  6e-140
NP_789845 (OMIM: 609988) inorganic pyrophosphatase ( 334) 1084 263.0 5.8e-70
NP_789842 (OMIM: 609988) inorganic pyrophosphatase ( 232) 1077 261.3 1.3e-69
NP_789843 (OMIM: 609988) inorganic pyrophosphatase ( 168)  801 196.5 3.1e-50
NP_066952 (OMIM: 179030) inorganic pyrophosphatase ( 289)  642 159.3 8.6e-39


>>NP_008834 (OMIM: 609988) inorganic pyrophosphatase 2,   (305 aa)
 initn: 2074 init1: 2074 opt: 2074  Z-score: 2633.5  bits: 495.4 E(85289): 6e-140
Smith-Waterman score: 2074; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305)

               10        20        30        40        50        60
pF1KE0 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 VKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIAINA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 VKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIAINA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 NDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 NDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 STHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 STHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVW
              250       260       270       280       290       300

            
pF1KE0 HFLGK
       :::::
NP_008 HFLGK
            

>>NP_789845 (OMIM: 609988) inorganic pyrophosphatase 2,   (334 aa)
 initn: 1077 init1: 1077 opt: 1084  Z-score: 1377.1  bits: 263.0 E(85289): 5.8e-70
Smith-Waterman score: 2006; 91.3% identity (91.3% similar) in 334 aa overlap (1-305:1-334)

               10        20        30        40        50        60
pF1KE0 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
               70        80        90       100       110       120

              130       140                                    150 
pF1KE0 VKDGKLRYVANIFPYKGYIWNYGTLPQ-----------------------------ILSC
       :::::::::::::::::::::::::::                             ::::
NP_789 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC
              130       140       150       160       170       180

             160       170       180       190       200       210 
pF1KE0 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL
              190       200       210       220       230       240

             220       230       240       250       260       270 
pF1KE0 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF
              250       260       270       280       290       300

             280       290       300     
pF1KE0 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
       ::::::::::::::::::::::::::::::::::
NP_789 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
              310       320       330    

>>NP_789842 (OMIM: 609988) inorganic pyrophosphatase 2,   (232 aa)
 initn: 1077 init1: 1077 opt: 1077  Z-score: 1370.7  bits: 261.3 E(85289): 1.3e-69
Smith-Waterman score: 1413; 76.1% identity (76.1% similar) in 305 aa overlap (1-305:1-232)

               10        20        30        40        50        60
pF1KE0 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
       ::::::::::::::                                              
NP_789 SPFHDIPLKVNSKE----------------------------------------------
               70                                                  

              130       140       150       160       170       180
pF1KE0 VKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIAINA
                                  :::::::::::::::::::::::::::::::::
NP_789 ---------------------------ILSCGEVIHVKILGILALIDEGETDWKLIAINA
                                      80        90       100       

              190       200       210       220       230       240
pF1KE0 NDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 NDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIK
       110       120       130       140       150       160       

              250       260       270       280       290       300
pF1KE0 STHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 STHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVW
       170       180       190       200       210       220       

            
pF1KE0 HFLGK
       :::::
NP_789 HFLGK
       230  

>>NP_789843 (OMIM: 609988) inorganic pyrophosphatase 2,   (168 aa)
 initn: 801 init1: 801 opt: 801  Z-score: 1022.8  bits: 196.5 E(85289): 3.1e-50
Smith-Waterman score: 854; 54.8% identity (55.1% similar) in 305 aa overlap (1-305:1-168)

               10        20        30        40        50        60
pF1KE0 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::        
NP_789 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF--------
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KE0 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
                                                                   
NP_789 ------------------------------------------------------------
                                                                   

              130       140       150       160       170       180
pF1KE0 VKDGKLRYVANIFPYKGYIWNYGTLPQILSCGEVIHVKILGILALIDEGETDWKLIAINA
                                                                   
NP_789 ------------------------------------------------------------
                                                                   

              190       200       210       220       230       240
pF1KE0 NDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIK
                .::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 ---------NIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIK
                      60        70        80        90       100   

              250       260       270       280       290       300
pF1KE0 STHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 STHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVW
           110       120       130       140       150       160   

            
pF1KE0 HFLGK
       :::::
NP_789 HFLGK
            

>>NP_066952 (OMIM: 179030) inorganic pyrophosphatase [Ho  (289 aa)
 initn: 1105 init1: 640 opt: 642  Z-score: 817.4  bits: 159.3 E(85289): 8.6e-39
Smith-Waterman score: 1031; 54.3% identity (74.2% similar) in 291 aa overlap (32-293:1-272)

              10        20        30        40        50        60 
pF1KE0 SALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYIS
                                     :. . ::::. : : .::.:.::  :.:::
NP_066                               MSGFSTEERAAPFSLEYRVFLKNEKGQYIS
                                             10        20        30

              70        80        90       100       110       120 
pF1KE0 PFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQYV
       ::::::. ..                 ...:.:.::.:::.:::::::::.:.::::: :
NP_066 PFHDIPIYAD-----------------KDVFHMVVEVPRWSNAKMEIATKDPLNPIKQDV
               40                         50        60        70   

             130       140                           150           
pF1KE0 KDGKLRYVANIFPYKGYIWNYGTLPQ--------------------ILSC---------G
       : ::::::::.:::::::::::..::                    :  :         :
NP_066 KKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARG
            80        90       100       110       120       130   

            160       170       180       190       200       210  
pF1KE0 EVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLY
       :.: ::.:::::.:::::::::.::::..::.:....::.:::..::::::::..::: :
NP_066 EIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRY
           140       150       160       170       180       190   

            220       230       240       250       260       270  
pF1KE0 KVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPFR
       :::::::::.::::.:::.: ::...:::::. ::::. :: :: .:.: :. .:.:::.
NP_066 KVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTLSESPFK
           200       210       220       230       240       250   

            280       290       300          
pF1KE0 CTQEEARSLVESVSSSPNKESNEEEQVWHFLGK     
       :  . ::..:...   :  ::                 
NP_066 CDPDAARAIVDALP--PPCESACTVPTDVDKWFHHQKN
           260         270       280         




305 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 05:27:57 2016 done: Thu Nov  3 05:27:58 2016
 Total Scan time:  6.980 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com