Result of FASTA (ccds) for pF1KE0458
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0458, 226 aa
  1>>>pF1KE0458 226 - 226 aa - 226 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3363+/-0.000683; mu= 13.3310+/- 0.041
 mean_var=60.9962+/-12.241, 0's: 0 Z-trim(109.6): 22  B-trim: 17 in 1/49
 Lambda= 0.164219
 statistics sampled from 10970 (10990) to 10970 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.338), width:  16
 Scan time:  2.240

The best scores are:                                      opt bits E(32554)
CCDS8957.1 METTL21B gene_id:25895|Hs108|chr12      ( 226) 1534 371.5 2.5e-103
CCDS31848.1 METTL21B gene_id:25895|Hs108|chr12     ( 149)  653 162.7 1.2e-40
CCDS2376.1 METTL21A gene_id:151194|Hs108|chr2      ( 218)  540 136.0 1.9e-32
CCDS32003.1 METTL21C gene_id:196541|Hs108|chr13    ( 264)  303 79.8 1.8e-15
CCDS9696.2 VCPKMT gene_id:79609|Hs108|chr14        ( 229)  286 75.8 2.6e-14
CCDS41951.1 VCPKMT gene_id:79609|Hs108|chr14       ( 194)  273 72.7 1.9e-13
CCDS82562.1 METTL21A gene_id:151194|Hs108|chr2     (  90)  231 62.6 9.5e-11


>>CCDS8957.1 METTL21B gene_id:25895|Hs108|chr12           (226 aa)
 initn: 1534 init1: 1534 opt: 1534  Z-score: 1968.5  bits: 371.5 E(32554): 2.5e-103
Smith-Waterman score: 1534; 100.0% identity (100.0% similar) in 226 aa overlap (1-226:1-226)

               10        20        30        40        50        60
pF1KE0 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS
              130       140       150       160       170       180

              190       200       210       220      
pF1KE0 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
       ::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 KMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
              190       200       210       220      

>>CCDS31848.1 METTL21B gene_id:25895|Hs108|chr12          (149 aa)
 initn: 653 init1: 653 opt: 653  Z-score: 843.3  bits: 162.7 E(32554): 1.2e-40
Smith-Waterman score: 653; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97)

               10        20        30        40        50        60
pF1KE0 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
       :::::::::::::::::::::::::::::::::::::                       
CCDS31 LSLCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGAYGLVRETEDDVIEQELWRGMRG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 PAGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLAS
                                                                   
CCDS31 ACGHALSMSTMTPWESIKGSSVRGGCYHH                               
              130       140                                        

>>CCDS2376.1 METTL21A gene_id:151194|Hs108|chr2           (218 aa)
 initn: 449 init1: 278 opt: 540  Z-score: 696.0  bits: 136.0 E(32554): 1.9e-32
Smith-Waterman score: 540; 46.2% identity (75.4% similar) in 195 aa overlap (33-224:24-215)

             10        20        30        40        50        60  
pF1KE0 DPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALS
                                     : : .:.. : :..  .::::: :::::. 
CCDS23        MALVPYEETTEFGLQKFHKPLATFSFANHTIQIRQDW-RHLGVAAVVWDAAIV
                      10        20        30         40        50  

             70        80        90       100       110       120  
pF1KE0 LCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPA
       : .:.:   :..::....:::::::.:::.::: :. :::::  .::: ...:::::.: 
CCDS23 LSTYLEMGAVELRGRSAVELGAGTGLVGIVAALLGAHVTITDRKVALEFLKSNVQANLPP
             60        70        80        90       100       110  

              130       140        150       160       170         
pF1KE0 GGQAQ--VRALSWGIDHHVF-PANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLA
         :..  :. :.:: .   : :...::.:::::.::: ::  :: ::.:::  :..: ::
CCDS23 HIQTKTVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLQTLEHLCSNHSVILLA
            120       130       140       150       160       170  

     180       190       200       210       220       
pF1KE0 SKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA 
        ..: :.  .. :  .: ..: .. .. : ...:.::.:..:. .   
CCDS23 CRIRYER--DNNFLAMLERQFTVRKVHYDPEKDVHIYEAQKRNQKEDL
              180       190       200       210        

>>CCDS32003.1 METTL21C gene_id:196541|Hs108|chr13         (264 aa)
 initn: 192 init1: 108 opt: 303  Z-score: 391.3  bits: 79.8 E(32554): 1.8e-15
Smith-Waterman score: 303; 32.8% identity (65.7% similar) in 201 aa overlap (26-217:65-258)

                    10        20        30        40        50     
pF1KE0      MADPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAAR
                                     ::... .. : :. ..: ... :    .: 
CCDS32 KDSTGGVLEESNKIEPSLHSLQKFVPTDYASYTQE-HYRFAGKEIVIQESIESY---GAV
           40        50        60         70        80           90

          60          70        80        90       100       110   
pF1KE0 VWDAALSLCNYFE--SQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQ
       :: .:..::.:.:  .....:.  :..:.::: :.:.:.:.. :..:: :::: .: ..:
CCDS32 VWPGAMALCQYLEEHAEELNFQDAKILEIGAGPGLVSIVASILGAQVTATDLPDVLGNLQ
              100       110       120       130       140       150

           120         130        140          150       160       
pF1KE0 GNVQANVP--AGGQAQVRALSWGID-HHVFPAN---YDLVLGADIVYLEPTFPLLLGTLQ
        :.  :.   ..   .:. : :: :  . :: .   :: ::..:.:: .  .  :: :. 
CCDS32 YNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSAFYYDYVLASDVVYHHYFLDKLLTTMV
              160       170       180       190       200       210

       170        180       190       200       210       220      
pF1KE0 HLCRPHGTIYL-ASKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
       .: .: ::. : :.:.:   .:.  :   . : :.  :  .  . .:....         
CCDS32 YLSQP-GTVLLWANKFR--FSTDYEFLDKFKQVFDTTLLAEYPESSVKLFKGILKWD   
               220         230       240       250       260       

>>CCDS9696.2 VCPKMT gene_id:79609|Hs108|chr14             (229 aa)
 initn: 256 init1: 128 opt: 286  Z-score: 370.5  bits: 75.8 E(32554): 2.6e-14
Smith-Waterman score: 298; 32.8% identity (60.3% similar) in 204 aa overlap (37-224:25-226)

         10        20        30        40        50        60      
pF1KE0 DPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNY
                                     : :: . :   :  ::.  :::::. : .:
CCDS96       MADTLESSLEDPLRSFVRVLEKRDGTVLRLQQY--SSGGVGCVVWDAAIVLSKY
                     10        20        30          40        50  

         70              80        90       100       110       120
pF1KE0 FESQNVDFRG------KKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
       .:. . .  :      ..:.:::.::: ::..::  :.::..:::    . .. :.. : 
CCDS96 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNK
             60        70        80        90       100       110  

               130       140       150       160       170         
pF1KE0 P-AGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTI---
         . :..:...:.:: . . ::.  :..: :: .: : ..  :: ::. .   .  :   
CCDS96 HLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICC
            120       130       140       150       160       170  

        180       190       200          210          220       
pF1KE0 YLASKMRKEHGTESFFQHLLPQHFQLE---LAQRDED---ENVNIYRARHREPRPA 
       :    : :.   :. . .::   :..:   : ..::.   :...:   :... .   
CCDS96 YEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS
            180       190       200       210       220         

>>CCDS41951.1 VCPKMT gene_id:79609|Hs108|chr14            (194 aa)
 initn: 246 init1: 118 opt: 273  Z-score: 355.0  bits: 72.7 E(32554): 1.9e-13
Smith-Waterman score: 273; 37.1% identity (65.0% similar) in 140 aa overlap (37-169:25-162)

         10        20        30        40        50        60      
pF1KE0 DPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALSLCNY
                                     : :: . :   :  ::.  :::::. : .:
CCDS41       MADTLESSLEDPLRSFVRVLEKRDGTVLRLQQY--SSGGVGCVVWDAAIVLSKY
                     10        20        30          40        50  

         70              80        90       100       110       120
pF1KE0 FESQNVDFRG------KKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANV
       .:. . .  :      ..:.:::.::: ::..::  :.::..:::    . .. :.. : 
CCDS41 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNK
             60        70        80        90       100       110  

               130       140       150       160       170         
pF1KE0 P-AGGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLA
         . :..:...:.:: . . ::.  :..: :: .: : ..  :: ::. .          
CCDS41 HLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICC
            120       130       140       150       160       170  

     180       190       200       210       220      
pF1KE0 SKMRKEHGTESFFQHLLPQHFQLELAQRDEDENVNIYRARHREPRPA
                                                      
CCDS41 YEQRTMGKNPEIEKKYFEKFPS                         
            180       190                             

>>CCDS82562.1 METTL21A gene_id:151194|Hs108|chr2          (90 aa)
 initn: 205 init1: 205 opt: 231  Z-score: 306.4  bits: 62.6 E(32554): 9.5e-11
Smith-Waterman score: 231; 52.9% identity (79.4% similar) in 68 aa overlap (33-100:24-90)

             10        20        30        40        50        60  
pF1KE0 DPGPDPESESESVFPREVGLFADSYSEKSQFCFCGHVLTITQNFGSRLGVAARVWDAALS
                                     : : .:.. : :..  .::::: :::::. 
CCDS82        MALVPYEETTEFGLQKFHKPLATFSFANHTIQIRQDW-RHLGVAAVVWDAAIV
                      10        20        30         40        50  

             70        80        90       100       110       120  
pF1KE0 LCNYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPLALEQIQGNVQANVPA
       : .:.:   :..::....:::::::.:::.::: :: .                      
CCDS82 LSTYLEMGAVELRGRSAVELGAGTGLVGIVAALLGGGI                      
             60        70        80        90                      

            130       140       150       160       170       180  
pF1KE0 GGQAQVRALSWGIDHHVFPANYDLVLGADIVYLEPTFPLLLGTLQHLCRPHGTIYLASKM




226 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:22:54 2016 done: Thu Nov  3 07:22:54 2016
 Total Scan time:  2.240 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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