Result of FASTA (ccds) for pF1KE0425
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0425, 373 aa
  1>>>pF1KE0425 373 - 373 aa - 373 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3764+/-0.000953; mu= 15.7455+/- 0.057
 mean_var=63.9724+/-12.879, 0's: 0 Z-trim(104.6): 30  B-trim: 0 in 0/50
 Lambda= 0.160353
 statistics sampled from 7977 (7990) to 7977 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.245), width:  16
 Scan time:  2.410

The best scores are:                                      opt bits E(32554)
CCDS14717.1 NSDHL gene_id:50814|Hs108|chrX         ( 373) 2485 583.8 8.1e-167
CCDS42205.1 SDR42E1 gene_id:93517|Hs108|chr16      ( 393)  514 127.9 1.5e-29
CCDS903.1 HSD3B1 gene_id:3283|Hs108|chr1           ( 373)  324 83.9 2.5e-16
CCDS902.1 HSD3B2 gene_id:3284|Hs108|chr1           ( 372)  303 79.0 7.3e-15
CCDS10698.1 HSD3B7 gene_id:80270|Hs108|chr16       ( 369)  286 75.1 1.1e-13


>>CCDS14717.1 NSDHL gene_id:50814|Hs108|chrX              (373 aa)
 initn: 2485 init1: 2485 opt: 2485  Z-score: 3108.4  bits: 583.8 E(32554): 8.1e-167
Smith-Waterman score: 2485; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)

               10        20        30        40        50        60
pF1KE0 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
              310       320       330       340       350       360

              370   
pF1KE0 RTVQSFRHLRRVK
       :::::::::::::
CCDS14 RTVQSFRHLRRVK
              370   

>>CCDS42205.1 SDR42E1 gene_id:93517|Hs108|chr16           (393 aa)
 initn: 503 init1: 171 opt: 514  Z-score: 643.7  bits: 127.9 E(32554): 1.5e-29
Smith-Waterman score: 604; 33.8% identity (65.3% similar) in 346 aa overlap (34-360:5-348)

            10        20        30        40        50        60   
pF1KE0 AVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYA
                                     ..: .   . ::::..: ..   :   :  
CCDS42                           MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVH
                                         10        20        30    

            70          80        90         100       110         
pF1KE0 VNVFDIQQGFDN-PQ-VRFFLGDLCSRQDLYPALKG--VNTVFHCASPPPSSN---NKEL
       : .:::..  .. :. ..:. ::.   .:.  :..   :. ::: ::   :.    :..:
CCDS42 VILFDISSPAQTIPEGIKFIQGDIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNL
           40        50        60        70        80        90    

        120       130       140       150       160          170   
pF1KE0 FYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYA---MKPIDYYT
       . .::  :: :....:..  : .:. ::. .::: :  :.:: :.:::    ..: :.:.
CCDS42 IKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHP-DHYS
          100       110       120       130       140        150   

           180           190        200       210       220        
pF1KE0 ETKILQERAVLGAN----DPEKNFLTT-AIRPHGIFGPRDPQLVPILIEAARNGKMKFVI
       .:: . :. :: ::    :   . : : :.:: ::.:: . . .: ..   ..: .::: 
CCDS42 RTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVY
           160       170       180       190       200       210   

      230       240       250         260       270       280      
pF1KE0 GNGKNLVDFTFVENVVHGHILAAEQLSRDS--TLGGKAFHITNDEPIPFWTFLSRILTGL
       :. ..::.:. :.:.:..::::.: :  :.    .:. . :.. .:.  . :.  .. ::
CCDS42 GDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEGL
           220       230       240       250       260       270   

        290       300       310       320       330       340      
pF1KE0 NYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKA
       .:  :. ..:  ..: .:.:  .. .... . ..:: .:  .:  .:. ::.: :.::: 
CCDS42 GYTFPSTRLPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKE
           280       290       300       310       320       330   

          350       360       370                                  
pF1KE0 MGY--QPLVTMDDAMERTVQSFRHLRRVK                               
       .::  ::.  ...:.:                                            
CCDS42 LGYKAQPF-DLQEAVEWFKAHGHGRSSGSRDSECFVWDGLLVFLLIIAVLMWLPSSVILS
           340        350       360       370       380       390  

>>CCDS903.1 HSD3B1 gene_id:3283|Hs108|chr1                (373 aa)
 initn: 206 init1:  70 opt: 324  Z-score: 406.5  bits: 83.9 E(32554): 2.5e-16
Smith-Waterman score: 378; 27.2% identity (58.9% similar) in 353 aa overlap (40-364:6-355)

      10        20        30        40        50        60         
pF1KE0 RDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGY--AVNVF
                                     : : :..:::::.... :. .     . :.
CCDS90                          MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVL
                                        10        20        30     

              70        80            90       100         110     
pF1KE0 D------IQQGFDNPQVRFFL----GDLCSRQDLYPALKGVNTVFH--CASPPPSSNNKE
       :      ... :.. : .  :    ::. ..  :  : . :....:  :     . ...:
CCDS90 DKAFGPELREEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRE
          40        50        60        70        80        90     

         120       130       140           150       160       170 
pF1KE0 LFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDY
        .. ::  ::. ..:.: .:.:  .: :::  :     .. . :.:: :. :        
CCDS90 SIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEI-IQNGHEEEPLENTWPAP
         100       110       120       130        140       150    

             180       190           200       210       220       
pF1KE0 YTETKILQERAVLGANDPE-KN---FLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFV
       : ..: : :.:::.::  . ::   . : :.::  :.:  .  :   . ::  :. .   
CCDS90 YPHSKKLAEKAVLAANGWNLKNGGTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSS
          160       170       180       190       200       210    

       230       240       250          260       270       280    
pF1KE0 IGNGKNLVDFTFVENVVHGHILAAEQLS---RDSTLGGKAFHITNDEPIPFWTFLSRILT
       .:. .. :. ..: ::. .:::: . :.   .  .. :. ..:..: :   .  :.  :.
CCDS90 VGKFST-VNPVYVGNVAWAHILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLS
          220        230       240       250       260       270   

             290       300       310       320       330       340 
pF1KE0 ---GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCE
          ::  .. .. .:  . :....:: .. ... :.   .: :.   :.:...   .: .
CCDS90 KEFGLRLDS-RWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYK
           280        290       300       310       320       330  

             350       360       370            
pF1KE0 RAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK         
       .:.. ..:.:: . ..: ..::.                  
CCDS90 KAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
            340       350       360       370   

>>CCDS902.1 HSD3B2 gene_id:3284|Hs108|chr1                (372 aa)
 initn: 285 init1: 127 opt: 303  Z-score: 380.3  bits: 79.0 E(32554): 7.3e-15
Smith-Waterman score: 407; 29.0% identity (58.9% similar) in 355 aa overlap (40-364:5-354)

      10        20        30        40        50        60         
pF1KE0 RDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDI
                                     : : :..:.:::..:. :. .    ..  .
CCDS90                           MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRAL
                                         10        20        30    

      70        80        90                    100         110    
pF1KE0 QQGFDNPQVRFFLGDLCSRQDLY---------PALK----GVNTVFH--CASPPPSSNNK
       ...:  :..:  .. : .:  :          : ::     :..:.:  :     . ...
CCDS90 DKAF-RPELREEFSKLQNRTKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHR
            40        50        60        70        80        90   

          120       130       140           150       160       170
pF1KE0 ELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPID
       : .. ::  ::. ..:.: .:.:  .: :::  :     .. . :.:: :. :       
CCDS90 ESIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEI-IQNGHEEEPLENTWPT
           100       110       120       130        140       150  

              180       190           200       210       220      
pF1KE0 YYTETKILQERAVLGANDPE-KN---FLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKF
        :  .: : :.:::.::  . ::   . : :.::  :.:   : :   . ::  :. .  
CCDS90 PYPYSKKLAEKAVLAANGWNLKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILS
            160       170       180       190       200       210  

        230       240       250           260       270       280  
pF1KE0 VIGNGKNLVDFTFVENVVHGHILAAEQLSRDS----TLGGKAFHITNDEPIPFWTFLSRI
        .:. .. :. ..: ::. .:::: . : ::     .. :. ..:..: :   .  :. :
CCDS90 SVGKFST-VNPVYVGNVAWAHILALRAL-RDPKKAPSVRGQFYYISDDTPHQSYDNLNYI
             220       230        240       250       260       270

               290       300       310       320       330         
pF1KE0 LT---GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYS
       :.   ::  .. .. .:  . :....:: .. ...::. . :: :.   :.:...   .:
CCDS90 LSKEFGLRLDS-RWSLPLTLMYWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFS
              280        290       300       310       320         

     340       350       360       370            
pF1KE0 CERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK         
        ..:.. ..:.:: . ..: ..::.                  
CCDS90 YKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
     330       340       350       360       370  

>>CCDS10698.1 HSD3B7 gene_id:80270|Hs108|chr16            (369 aa)
 initn: 427 init1: 174 opt: 286  Z-score: 359.1  bits: 75.1 E(32554): 1.1e-13
Smith-Waterman score: 446; 30.0% identity (55.8% similar) in 353 aa overlap (34-363:6-358)

            10        20        30        40        50        60   
pF1KE0 AVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYA
                                     : :     : :: ::::.:.:..:: :   
CCDS10                          MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPR
                                        10        20        30     

               70             80          90       100         110 
pF1KE0 VN---VFDIQQG-----FDNPQVRF--FLGDLCSRQDLYPALKGVNTVFHCASPPP--SS
       ..   ::: . :     . .  ::   . ::. . ...  :. :...:.: :.     . 
CCDS10 LGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGR
          40        50        60        70        80        90     

             120       130       140          150       160        
pF1KE0 NNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI---FEGVDIKNGTEDLPYAMKP
        . . ...::  ::.::::.: ..:.. :. :::  :.    .:  .  :.:: ::    
CCDS10 ASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVH
         100       110       120       130       140       150     

      170       180       190           200       210       220    
pF1KE0 IDYYTETKILQERAVLGANDPEKN----FLTTAIRPHGIFGPRDPQLVPILIEAARNGKM
          :  .: : :  :: ::  .      ..: :.:: ::.:     .  .  .. : :  
CCDS10 RHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGW
         160       170       180       190       200       210     

          230       240       250       260        270        280  
pF1KE0 KFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTL-GGKAFHITNDEPI-PFWTFLSRI
        :    ..     ..: ::.  :.:::..: . .:: ::...   .  :   .  :  ..
CCDS10 LFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEF
         220       230       240       250       260       270     

              290       300       310       320       330       340
pF1KE0 L--TGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSC
       :   ::   . .  .:::.  .:: : .::  .. :..   : ..:. .:.:.:    : 
CCDS10 LGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVST
         280       290       300       310       320       330     

              350       360       370    
pF1KE0 ERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK 
       ..:.. .::.:: . .:.  ::.           
CCDS10 DKAQRHFGYEPLFSWEDSRTRTILWVQAATGSAQ
         340       350       360         




373 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 10:36:40 2016 done: Thu Nov  3 10:36:40 2016
 Total Scan time:  2.410 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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