Result of FASTA (omim) for pF1KB5080
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5080, 725 aa
  1>>>pF1KB5080 725 - 725 aa - 725 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8865+/-0.000471; mu= 16.1852+/- 0.029
 mean_var=77.5677+/-16.207, 0's: 0 Z-trim(110.1): 74  B-trim: 756 in 1/53
 Lambda= 0.145624
 statistics sampled from 18341 (18415) to 18341 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.565), E-opt: 0.2 (0.216), width:  16
 Scan time: 10.460

The best scores are:                                      opt bits E(85289)
NP_064551 (OMIM: 210200,609010) methylcrotonoyl-Co ( 725) 4715 1001.1       0
XP_011511294 (OMIM: 210200,609010) PREDICTED: meth ( 687) 4456 946.7       0
XP_016862364 (OMIM: 210200,609010) PREDICTED: meth ( 616) 4008 852.5       0
XP_016862363 (OMIM: 210200,609010) PREDICTED: meth ( 616) 4008 852.5       0
XP_006713765 (OMIM: 210200,609010) PREDICTED: meth ( 616) 4008 852.5       0
NP_001280202 (OMIM: 210200,609010) methylcrotonoyl ( 608) 3647 776.7       0
XP_011511295 (OMIM: 210200,609010) PREDICTED: meth ( 472) 3023 645.5 1.4e-184
NP_001121164 (OMIM: 232000,606054) propionyl-CoA c ( 702) 1603 347.3 1.3e-94
XP_016876098 (OMIM: 232000,606054) PREDICTED: prop ( 695) 1592 345.0 6.2e-94
NP_000273 (OMIM: 232000,606054) propionyl-CoA carb ( 728) 1592 345.0 6.4e-94
XP_016876103 (OMIM: 232000,606054) PREDICTED: prop ( 655) 1483 322.0 4.6e-87
XP_016876095 (OMIM: 232000,606054) PREDICTED: prop ( 718) 1483 322.1   5e-87
XP_005254116 (OMIM: 232000,606054) PREDICTED: prop ( 640) 1472 319.7 2.2e-86
XP_016876102 (OMIM: 232000,606054) PREDICTED: prop ( 669) 1472 319.7 2.3e-86
XP_016876101 (OMIM: 232000,606054) PREDICTED: prop ( 681) 1472 319.7 2.4e-86
NP_001171475 (OMIM: 232000,606054) propionyl-CoA c ( 681) 1472 319.7 2.4e-86
XP_016876100 (OMIM: 232000,606054) PREDICTED: prop ( 683) 1472 319.7 2.4e-86
XP_011519395 (OMIM: 232000,606054) PREDICTED: prop ( 699) 1472 319.7 2.4e-86
XP_016876097 (OMIM: 232000,606054) PREDICTED: prop ( 710) 1472 319.8 2.4e-86
XP_016876096 (OMIM: 232000,606054) PREDICTED: prop ( 711) 1472 319.8 2.4e-86
XP_016876094 (OMIM: 232000,606054) PREDICTED: prop ( 744) 1472 319.8 2.5e-86
XP_016876104 (OMIM: 232000,606054) PREDICTED: prop ( 624) 1470 319.3 2.9e-86
XP_016876105 (OMIM: 232000,606054) PREDICTED: prop ( 551) 1469 319.1   3e-86
XP_016876099 (OMIM: 232000,606054) PREDICTED: prop ( 689) 1308 285.3 5.6e-76
XP_016873361 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_016873358 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
NP_001035806 (OMIM: 266150,608786) pyruvate carbox (1178) 1299 283.5 3.3e-75
XP_011543388 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_016873357 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_016873360 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_005274089 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
NP_000911 (OMIM: 266150,608786) pyruvate carboxyla (1178) 1299 283.5 3.3e-75
XP_005274088 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
NP_071504 (OMIM: 266150,608786) pyruvate carboxyla (1178) 1299 283.5 3.3e-75
XP_016873359 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_006718641 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_016876106 (OMIM: 232000,606054) PREDICTED: prop ( 413)  682 153.7 1.4e-36
XP_016876107 (OMIM: 232000,606054) PREDICTED: prop ( 395)  562 128.4 5.3e-29
XP_011536567 (OMIM: 601557) PREDICTED: acetyl-CoA  (1304)  541 124.3 3.1e-27
XP_016874741 (OMIM: 601557) PREDICTED: acetyl-CoA  (2193)  541 124.4 4.9e-27
XP_011536566 (OMIM: 601557) PREDICTED: acetyl-CoA  (2249)  541 124.4   5e-27
XP_006719430 (OMIM: 601557) PREDICTED: acetyl-CoA  (2256)  541 124.4   5e-27
XP_011536565 (OMIM: 601557) PREDICTED: acetyl-CoA  (2395)  541 124.4 5.2e-27
NP_001084 (OMIM: 601557) acetyl-CoA carboxylase 2  (2458)  541 124.4 5.4e-27
XP_005253933 (OMIM: 601557) PREDICTED: acetyl-CoA  (2458)  541 124.4 5.4e-27
XP_011536561 (OMIM: 601557) PREDICTED: acetyl-CoA  (2458)  541 124.4 5.4e-27
XP_011523006 (OMIM: 200350,613933) PREDICTED: acet (2268)  534 122.9 1.4e-26
XP_005257324 (OMIM: 200350,613933) PREDICTED: acet (2268)  534 122.9 1.4e-26
NP_942135 (OMIM: 200350,613933) acetyl-CoA carboxy (2268)  534 122.9 1.4e-26
NP_942134 (OMIM: 200350,613933) acetyl-CoA carboxy (2288)  534 122.9 1.4e-26


>>NP_064551 (OMIM: 210200,609010) methylcrotonoyl-CoA ca  (725 aa)
 initn: 4715 init1: 4715 opt: 4715  Z-score: 5353.1  bits: 1001.1 E(85289):    0
Smith-Waterman score: 4715; 99.7% identity (99.7% similar) in 725 aa overlap (1-725:1-725)

               10        20        30        40        50        60
pF1KB5 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 AAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 YHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_064 YHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 DDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 DDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 KLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 RIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 RQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFE
       ::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_064 RQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 AGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB5 SGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKC
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB5 SVNGVASKAKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SVNGVASKAKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB5 FVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 FVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESD
              670       680       690       700       710       720

            
pF1KB5 KRESE
       :::::
NP_064 KRESE
            

>>XP_011511294 (OMIM: 210200,609010) PREDICTED: methylcr  (687 aa)
 initn: 4456 init1: 4456 opt: 4456  Z-score: 5059.4  bits: 946.7 E(85289):    0
Smith-Waterman score: 4456; 99.7% identity (99.7% similar) in 687 aa overlap (39-725:1-687)

       10        20        30        40        50        60        
pF1KB5 VLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEIACRVMRTA
                                     ::::::::::::::::::::::::::::::
XP_011                               MKYTTATGRNITKVLIANRGEIACRVMRTA
                                             10        20        30

       70        80        90       100       110       120        
pF1KB5 KKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPG
               40        50        60        70        80        90

      130       140       150       160       170       180        
pF1KB5 CGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSD
              100       110       120       130       140       150

      190       200       210       220       230       240        
pF1KB5 QCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEK
       ::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_011 QCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEK
              160       170       180       190       200       210

      250       260       270       280       290       300        
pF1KB5 FVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVR
              220       230       240       250       260       270

      310       320       330       340       350       360        
pF1KB5 AAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKI
              280       290       300       310       320       330

      370       380       390       400       410       420        
pF1KB5 PLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSV
              340       350       360       370       380       390

      430       440       450       460       470       480        
pF1KB5 HYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDF
       ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_011 HYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDF
              400       410       420       430       440       450

      490       500       510       520       530       540        
pF1KB5 IPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNIS
              460       470       480       490       500       510

      550       560       570       580       590       600        
pF1KB5 YTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASK
              520       530       540       550       560       570

      610       620       630       640       650       660        
pF1KB5 AKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKV
              580       590       600       610       620       630

      670       680       690       700       710       720     
pF1KB5 KAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
              640       650       660       670       680       

>>XP_016862364 (OMIM: 210200,609010) PREDICTED: methylcr  (616 aa)
 initn: 4008 init1: 4008 opt: 4008  Z-score: 4551.4  bits: 852.5 E(85289):    0
Smith-Waterman score: 4008; 99.7% identity (99.7% similar) in 616 aa overlap (110-725:1-616)

      80        90       100       110       120       130         
pF1KB5 SEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFA
                                     ::::::::::::::::::::::::::::::
XP_016                               MEKIIQVAKTSAAQAIHPGCGFLSENMEFA
                                             10        20        30

     140       150       160       170       180       190         
pF1KB5 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
               40        50        60        70        80        90

     200       210       220       230       240       250         
pF1KB5 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHVEVQ
       :::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQ
              100       110       120       130       140       150

     260       270       280       290       300       310         
pF1KB5 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
              160       170       180       190       200       210

     320       330       340       350       360       370         
pF1KB5 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
              220       230       240       250       260       270

     380       390       400       410       420       430         
pF1KB5 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
              280       290       300       310       320       330

     440       450       460       470       480       490         
pF1KB5 WAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 WAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
              340       350       360       370       380       390

     500       510       520       530       540       550         
pF1KB5 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
              400       410       420       430       440       450

     560       570       580       590       600       610         
pF1KB5 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
              460       470       480       490       500       510

     620       630       640       650       660       670         
pF1KB5 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
              520       530       540       550       560       570

     680       690       700       710       720     
pF1KB5 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
              580       590       600       610      

>>XP_016862363 (OMIM: 210200,609010) PREDICTED: methylcr  (616 aa)
 initn: 4008 init1: 4008 opt: 4008  Z-score: 4551.4  bits: 852.5 E(85289):    0
Smith-Waterman score: 4008; 99.7% identity (99.7% similar) in 616 aa overlap (110-725:1-616)

      80        90       100       110       120       130         
pF1KB5 SEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFA
                                     ::::::::::::::::::::::::::::::
XP_016                               MEKIIQVAKTSAAQAIHPGCGFLSENMEFA
                                             10        20        30

     140       150       160       170       180       190         
pF1KB5 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
               40        50        60        70        80        90

     200       210       220       230       240       250         
pF1KB5 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHVEVQ
       :::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQ
              100       110       120       130       140       150

     260       270       280       290       300       310         
pF1KB5 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
              160       170       180       190       200       210

     320       330       340       350       360       370         
pF1KB5 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
              220       230       240       250       260       270

     380       390       400       410       420       430         
pF1KB5 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
              280       290       300       310       320       330

     440       450       460       470       480       490         
pF1KB5 WAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 WAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
              340       350       360       370       380       390

     500       510       520       530       540       550         
pF1KB5 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
              400       410       420       430       440       450

     560       570       580       590       600       610         
pF1KB5 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
              460       470       480       490       500       510

     620       630       640       650       660       670         
pF1KB5 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
              520       530       540       550       560       570

     680       690       700       710       720     
pF1KB5 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
              580       590       600       610      

>>XP_006713765 (OMIM: 210200,609010) PREDICTED: methylcr  (616 aa)
 initn: 4008 init1: 4008 opt: 4008  Z-score: 4551.4  bits: 852.5 E(85289):    0
Smith-Waterman score: 4008; 99.7% identity (99.7% similar) in 616 aa overlap (110-725:1-616)

      80        90       100       110       120       130         
pF1KB5 SEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFA
                                     ::::::::::::::::::::::::::::::
XP_006                               MEKIIQVAKTSAAQAIHPGCGFLSENMEFA
                                             10        20        30

     140       150       160       170       180       190         
pF1KB5 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
               40        50        60        70        80        90

     200       210       220       230       240       250         
pF1KB5 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHVEVQ
       :::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_006 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQ
              100       110       120       130       140       150

     260       270       280       290       300       310         
pF1KB5 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
              160       170       180       190       200       210

     320       330       340       350       360       370         
pF1KB5 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
              220       230       240       250       260       270

     380       390       400       410       420       430         
pF1KB5 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
              280       290       300       310       320       330

     440       450       460       470       480       490         
pF1KB5 WAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
       :::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_006 WAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
              340       350       360       370       380       390

     500       510       520       530       540       550         
pF1KB5 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
              400       410       420       430       440       450

     560       570       580       590       600       610         
pF1KB5 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
              460       470       480       490       500       510

     620       630       640       650       660       670         
pF1KB5 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
              520       530       540       550       560       570

     680       690       700       710       720     
pF1KB5 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
              580       590       600       610      

>>NP_001280202 (OMIM: 210200,609010) methylcrotonoyl-CoA  (608 aa)
 initn: 3647 init1: 3647 opt: 3647  Z-score: 4141.6  bits: 776.7 E(85289):    0
Smith-Waterman score: 3647; 99.3% identity (99.6% similar) in 564 aa overlap (162-725:45-608)

             140       150       160       170       180       190 
pF1KB5 LSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCL
                                     ..::::::::::::::::::::::::::::
NP_001 RQMKHIPSAPLPPSRATYLWRKSFKWPRPLLHSTSKSIMAAAGVPVVEGYHGEDQSDQCL
           20        30        40        50        60        70    

             200       210       220       230       240       250 
pF1KB5 KEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVD
       :::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 KEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVD
           80        90       100       110       120       130    

             260       270       280       290       300       310 
pF1KB5 TPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAK
          140       150       160       170       180       190    

             320       330       340       350       360       370 
pF1KB5 AVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLS
          200       210       220       230       240       250    

             380       390       400       410       420       430 
pF1KB5 QEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYD
          260       270       280       290       300       310    

             440       450       460       470       480       490 
pF1KB5 PMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFIPQ
       :::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_001 PMIAKLVVWAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQ
          320       330       340       350       360       370    

             500       510       520       530       540       550 
pF1KB5 HHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTR
          380       390       400       410       420       430    

             560       570       580       590       600       610 
pF1KB5 NMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKL
          440       450       460       470       480       490    

             620       630       640       650       660       670 
pF1KB5 IILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAG
          500       510       520       530       540       550    

             680       690       700       710       720     
pF1KB5 DSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
          560       570       580       590       600        

>>XP_011511295 (OMIM: 210200,609010) PREDICTED: methylcr  (472 aa)
 initn: 3023 init1: 3023 opt: 3023  Z-score: 3434.8  bits: 645.5 E(85289): 1.4e-184
Smith-Waterman score: 3023; 99.4% identity (99.6% similar) in 463 aa overlap (1-463:1-463)

               10        20        30        40        50        60
pF1KB5 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 AAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 YHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 YHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 DDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 KLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 RIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 RQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFE
       :::::::::::::::::::::::::::::::::::::::: .:                 
XP_011 RQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNINSLHFRLAVEED        
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KB5 AGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSS

>>NP_001121164 (OMIM: 232000,606054) propionyl-CoA carbo  (702 aa)
 initn: 1632 init1: 1263 opt: 1603  Z-score: 1819.9  bits: 347.3 E(85289): 1.3e-94
Smith-Waterman score: 1610; 39.5% identity (68.1% similar) in 722 aa overlap (10-715:11-702)

                10        20        30        40        50         
pF1KB5  MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGE
                 :..:..:.::        ::.     :  .. .  : ... :.:.:::::
NP_001 MAGFWVGTAPLVAAGRRGRW--------PPQ-----QLMLSAALRTLKTFDKILVANRGE
               10        20                     30        40       

      60        70        80        90       100       110         
pF1KB5 IACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKT
       :::::.:: ::.:..:::..:..: .:.:: :::::  .::::...:::.:. :... : 
NP_001 IACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKK
        50        60        70        80        90       100       

     120       130       140       150       160       170         
pF1KB5 SAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVE
       . :::.::: :::::: :::.    : ..::::   ::. :: :  :: .   : : .. 
NP_001 TRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIP
       110       120       130       140       150       160       

     180       190       200       210       220       230         
pF1KB5 GYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSF
       :. :  .. .   . ::.:::::::::  :::::::::. ...: .. .. . .:: .::
NP_001 GFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSF
       170       180       190       200       210       220       

     240       250       260       270       280       290         
pF1KB5 NDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVR
       .:: .:::::.:.:::.:.::.::.::::..: ::.::.:::.::..::::.  . .:.:
NP_001 GDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETR
       230       240       250       260       270       280       

     300       310       320       330       340       350         
pF1KB5 KKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQ
       . .:: ::  :.::.: .::::::..:::.:: :.:::::::::::::: ::: :::. .
NP_001 RAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEM
       290       300       310       320       330       340       

     360       370       380       390        400       410        
pF1KB5 LRIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNF-MPVAGPLVHLSTPRADPSTRIET
       .:.: :  .  .: .: ..: : : :.::::: ..: .:  : : . . :   :..:...
NP_001 IRVAKGYPLRHKQADIRINGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDS
       350       360       370       380       390       400       

      420       430       440       450       460       470        
pF1KB5 GVRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPE
       :.. :...:..:::::.::.....::  :: ..  .: .: : :.  :: .: ..  . .
NP_001 GIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSR
       410       420       430       440       450       460       

      480           490       500       510       520       530    
pF1KB5 FEAGNVHTDFI----PQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQF
       :  :.. : :.    :.  :  .:..  . :..:   : .:..       .: :.:. .:
NP_001 FVKGDISTKFLSDVYPDGFKGHMLTK--SEKNQLLAIASSLFV-------AFQLRAQ-HF
       470       480       490         500              510        

          540        550       560       570       580         590 
pF1KB5 SPFSSSSGRRLNIS-YTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLG--NLYS
       .  :     . .:. .  .. :.:   .:  .:. :. . .:.... . ..: .  :: :
NP_001 QENSRMPVIKPDIANWELSVKLHD---KVHTVVASNNGSVFSVEVDGSKLNVTSTWNLAS
       520       530       540          550       560       570    

             600       610           620           630       640   
pF1KB5 EGDCTYLKCSVNGVASKAKLIILEN----TIYLFSKEGSIEI----DIPVPKYLSSVSSQ
             :. ::.:.   .. .  :     .: ...   ...:       . :..    ..
NP_001 P----LLSVSVDGTQRTVQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTE
              580       590       600       610       620       630

           650       660       670       680       690       700   
pF1KB5 ETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGA
       .:..   .:: :..  : :: :: :  :. . :. ::::.... . : ::::.:  . : 
NP_001 DTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGD
              640       650       660       670       680       690

           710       720     
pF1KB5 QANRHTPLVEFEEEESDKRESE
        ...   :::.:          
NP_001 TVGEGDLLVELE          
              700            

>>XP_016876098 (OMIM: 232000,606054) PREDICTED: propiony  (695 aa)
 initn: 1631 init1: 1262 opt: 1592  Z-score: 1807.4  bits: 345.0 E(85289): 6.2e-94
Smith-Waterman score: 1593; 40.3% identity (69.2% similar) in 685 aa overlap (47-715:28-695)

         20        30        40        50        60        70      
pF1KB5 NRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEIACRVMRTAKKLGVQTV
                                     ... :.:.::::::::::.:: ::.:..::
XP_016    MEHVLYYSRQCLMVSRNLGSVGYDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTV
                  10        20        30        40        50       

         80        90       100       110       120       130      
pF1KB5 AVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENM
       :..:..: .:.:: :::::  .::::...:::.:. :... : . :::.::: :::::: 
XP_016 AIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENK
        60        70        80        90       100       110       

        140       150       160       170       180       190      
pF1KB5 EFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHAR
       :::.    : ..::::   ::. :: :  :: .   : : .. :. :  .. .   . ::
XP_016 EFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAR
       120       130       140       150       160       170       

        200       210       220       230       240       250      
pF1KB5 RIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHV
       .:::::::::  :::::::::. ...: .. .. . .:: .::.:: .:::::.:.:::.
XP_016 EIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHI
       180       190       200       210       220       230       

        260       270       280       290       300       310      
pF1KB5 EVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYV
       :.::.::.::::..: ::.::.:::.::..::::.  . .:.:. .:: ::  :.::.: 
XP_016 EIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYS
       240       250       260       270       280       290       

        320       330       340       350       360       370      
pF1KB5 GAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEIT
       .::::::..:::.:: :.:::::::::::::: ::: :::. ..:.: :  .  .: .: 
XP_016 SAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIR
       300       310       320       330       340       350       

        380       390        400       410       420       430     
pF1KB5 LQGHAFEARIYAEDPSNNF-MPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIA
       ..: : : :.::::: ..: .:  : : . . :   :..:...:.. :...:..:::::.
XP_016 INGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDSGIQPGSDISIYYDPMIS
       360       370       380       390       400       410       

         440       450       460       470       480           490 
pF1KB5 KLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFI----PQ
       ::.....::  :: ..  .: .: : :.  :: .: ..  . .:  :.. : :.    :.
XP_016 KLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSRFVKGDISTKFLSDVYPD
       420       430       440       450       460       470       

             500       510       520       530       540        550
pF1KB5 HHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNIS-YT
         :  .:..  . :..:   : .:..       .: :.:. .:.  :     . .:. . 
XP_016 GFKGHMLTK--SEKNQLLAIASSLFV-------AFQLRAQ-HFQENSRMPVIKPDIANWE
       480         490       500               510       520       

              560       570       580         590       600        
pF1KB5 RNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLG--NLYSEGDCTYLKCSVNGVASK
        .. :.:   .:  .:. :. . .:.... . ..: .  :: :      :. ::.:.   
XP_016 LSVKLHD---KVHTVVASNNGSVFSVEVDGSKLNVTSTWNLASP----LLSVSVDGTQRT
       530          540       550       560           570       580

      610           620           630       640       650       660
pF1KB5 AKLIILEN----TIYLFSKEGSIEI----DIPVPKYLSSVSSQETQGGPLAPMTGTIEKV
       .. .  :     .: ...   ...:       . :..    ...:..   .:: :..  :
XP_016 VQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTEDTSSVLRSPMPGVVVAV
              590       600       610       620       630       640

              670       680       690       700       710       720
pF1KB5 FVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESD
        :: :: :  :. . :. ::::.... . : ::::.:  . :  ...   :::.:     
XP_016 SVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE     
              650       660       670       680       690          

            
pF1KB5 KRESE

>>NP_000273 (OMIM: 232000,606054) propionyl-CoA carboxyl  (728 aa)
 initn: 1631 init1: 1262 opt: 1592  Z-score: 1807.1  bits: 345.0 E(85289): 6.4e-94
Smith-Waterman score: 1593; 40.3% identity (69.2% similar) in 685 aa overlap (47-715:61-728)

         20        30        40        50        60        70      
pF1KB5 NRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEIACRVMRTAKKLGVQTV
                                     ... :.:.::::::::::.:: ::.:..::
NP_000 LRTLKHVLYYSRQCLMVSRNLGSVGYDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTV
               40        50        60        70        80        90

         80        90       100       110       120       130      
pF1KB5 AVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENM
       :..:..: .:.:: :::::  .::::...:::.:. :... : . :::.::: :::::: 
NP_000 AIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENK
              100       110       120       130       140       150

        140       150       160       170       180       190      
pF1KB5 EFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHAR
       :::.    : ..::::   ::. :: :  :: .   : : .. :. :  .. .   . ::
NP_000 EFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAR
              160       170       180       190       200       210

        200       210       220       230       240       250      
pF1KB5 RIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHV
       .:::::::::  :::::::::. ...: .. .. . .:: .::.:: .:::::.:.:::.
NP_000 EIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHI
              220       230       240       250       260       270

        260       270       280       290       300       310      
pF1KB5 EVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYV
       :.::.::.::::..: ::.::.:::.::..::::.  . .:.:. .:: ::  :.::.: 
NP_000 EIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYS
              280       290       300       310       320       330

        320       330       340       350       360       370      
pF1KB5 GAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEIT
       .::::::..:::.:: :.:::::::::::::: ::: :::. ..:.: :  .  .: .: 
NP_000 SAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIR
              340       350       360       370       380       390

        380       390        400       410       420       430     
pF1KB5 LQGHAFEARIYAEDPSNNF-MPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIA
       ..: : : :.::::: ..: .:  : : . . :   :..:...:.. :...:..:::::.
NP_000 INGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDSGIQPGSDISIYYDPMIS
              400       410       420       430       440       450

         440       450       460       470       480           490 
pF1KB5 KLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFI----PQ
       ::.....::  :: ..  .: .: : :.  :: .: ..  . .:  :.. : :.    :.
NP_000 KLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSRFVKGDISTKFLSDVYPD
              460       470       480       490       500       510

             500       510       520       530       540        550
pF1KB5 HHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNIS-YT
         :  .:..  . :..:   : .:..       .: :.:. .:.  :     . .:. . 
NP_000 GFKGHMLTK--SEKNQLLAIASSLFV-------AFQLRAQ-HFQENSRMPVIKPDIANWE
                520       530              540        550       560

              560       570       580         590       600        
pF1KB5 RNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLG--NLYSEGDCTYLKCSVNGVASK
        .. :.:   .:  .:. :. . .:.... . ..: .  :: :      :. ::.:.   
NP_000 LSVKLHD---KVHTVVASNNGSVFSVEVDGSKLNVTSTWNLASP----LLSVSVDGTQRT
                 570       580       590       600           610   

      610           620           630       640       650       660
pF1KB5 AKLIILEN----TIYLFSKEGSIEI----DIPVPKYLSSVSSQETQGGPLAPMTGTIEKV
       .. .  :     .: ...   ...:       . :..    ...:..   .:: :..  :
NP_000 VQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTEDTSSVLRSPMPGVVVAV
           620       630       640       650       660       670   

              670       680       690       700       710       720
pF1KB5 FVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESD
        :: :: :  :. . :. ::::.... . : ::::.:  . :  ...   :::.:     
NP_000 SVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE     
           680       690       700       710       720             

            
pF1KB5 KRESE




725 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 22:11:24 2016 done: Sat Nov  5 22:11:26 2016
 Total Scan time: 10.460 Total Display time:  0.190

Function used was FASTA [36.3.4 Apr, 2011]
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